chronic spinal cord injury (lesi medula spinalis khronis)
DESCRIPTION
Chronic Spinal Cord Injury (Lesi Medula Spinalis Khronis). Darwin Amir Bgn Ilmu Penyakit Saraf Fakultas Kedokteran Universitas Andalas. The Spinal Cord. Cervical spinal erves. Thoracic spinal nerves. Conus medullaris. Cauda equina. Lumbar spinal nerves. Sacral spinal nerves. - PowerPoint PPT PresentationTRANSCRIPT
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Chronic Spinal Cord Injury (Lesi Medula Spinalis Khronis)
Darwin AmirBgn Ilmu Penyakit Saraf
Fakultas Kedokteran Universitas Andalas
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The Spinal CordCervical spinal erves
Thoracic spinal nerves
Lumbar spinal nerves
Sacral spinal nerves
Conus medullaris
Cauda equina
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PROYEKSI DERMATOM DIPERMUKAAN KULIT
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Ascending Spinal Cord Tract
• 1st order neuron - cutaneous receptors of skin and proprioceptors spinal cord or brain stem
• 2nd order neuron - to thalamus or cerebellum
• 3rd order neuron - to somatosensory cortex of cerebrum
Conducts sensory impulses upward through 3 successive chains of neurons
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Ascending Spinal Cord Tract
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The Spinal Cord
spinal cordspinal
nerve
vertebra
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Cross Section of Spinal CordWhite matter:Myelinated axons
forming nerve tracts
Fissure and sulcusThree columns:
◦Ventral ◦Dorsal◦Lateral
Gray matter: Neuron cell cell
bodies, dendrites, axons
‘Horns’:◦ Posterior (dorsal)◦ Anterior (ventral)◦ Lateral
Commissures:◦ Gray: Central canal ◦ White(see later for white matter
pathways)
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The Nervous SystemThe Spinal Cord-part of the CNS found within the Spinal column The spinal cord communicates with the sense organs and muscles below the level of the headBell-Magendie Law-the entering dorsal roots carry sensory information and the exiting ventral roots carry motor information to the muscles and GlandsDorsal Root Ganglia-clusters of neurons outside the spinal cord
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Nerve Pathways into the Spinal Cordsensory pathway
motor pathway
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Somatic Sensory Pathway
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CORTICOSPINAL TRACTS
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Symptoms and SignsMust be mastering in mindStart by understanding anatomy and
physiology of the Nervous SystemDon’s forget the of CNS systematically
- Anatomy of CNS - Physiology of CNS - Pathophysiology of the Disease - The steps to make the diagnosis
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Sensory disturbances▪ Soft touch, pain, temperature,
position, vibration impaired below the level of lesion
▪ Band like radicular pain/segmental paraesthesia at the level of lesion
▪ localised vertebral spine pain- destructive lesions
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Motor disturbances
▪ Paraplegia/quadriplegia▪ Acute-flaccid / Areflexic-spinal shock
latter-hypertonic / hyper reflexic, loss of superficial reflexes, Babinski +, flexor/extensor spasm
▪ Extension of hip, knee occurs in high spinal & Incomplete lesion
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• Flexion of hip , knee occur in low spinal & complete lesion
• At the level of lesion – paresis, atrophy, fasciculations,and areflexia(LMN signs) in a segmental distribution because of damage to the anterior horn cells and ventral roots
Motor disturbances
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Autononomic disturbances• initially atonic, latter spastic bladder,
rectal sphincter disturbances• orthostatic hypotension• trophic skin changes• anhydrosis• impaired temperature control• vasomotor instability• sexual disturbances• I/L horner syndrome
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Causes of Chronic Lesion° Tumour ° Multiple sclerosis° Vascular disorders ° Spinal epidural hematoma/abscess° Auto immune disease ° Herniated intervertebral disc° Combine degeneration of B12 Deficiences
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Complete spinal cord transection(Transverse myelopathy)
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Complete spinal cord transection(Transverse myelopathy)
All acsending tracts from below the level of the lesion and all descending tract from above the level of lesion interrupted. Motor, sensory, autonomic functions below the level of lesion disturbed
Causes : ° tumour ° multiple sclerosis ° vascular disorders ° spinal epidural hematoma/ ° spinal
epidural abscess ° herniated intervertebral disc ° auto immune disease
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Central spinal cord lesionSpinal cord damage starts centrally
and spreads centrifugallyDecussating fibers of spinothalamic
tract involved initiallyThermo anaesthesia, analgesia in a
”vest like” or “suspended” bilateral distribution with preservation soft touch sensation and proprioception--- dissociation of sensory loss
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Central spinal cord lesionForward extension of disease anterior
horn cells involved segmental neurogenic atrophy, paresis, areflexia
Lateral extension I/L Horner syndrome Kypho scoliosis Spastic paralysis Dorsal extension I/L Position sense, vibratory loss
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Central spinal cord lesionExtreme venterolateral extension thermo anaesthesia, analgesia with
sacral sparingNeuropathic arthropathyPain
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Posterior column disease
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Posterior column diseaseTabes dorsalis-tabetic neuro syphilis,
progressive locomotor ataxiaImpaired vibration and position sense, and
decreased tactile localisationLability of mechanical sensation threshold,
tactile & postural hallucinations, persistence of mechano receptor sensation, disturbances in the knowledge of extremity movement and positions (temporal & spatial disturbances)
Sensory ataxia in dark, Romberg (+)
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Ataxic / stomping/ double tapping gaitPositive sink signIn tabes dorsalis lancinating pain, urinary
incontinence, Negative patellar and ankle DTR, hypotonic limb, hyper extensible joints
abdominal, laryngeal crises, impaired light touch perception, Argyll robertson
pupil, optic atrophy, ptosis, ophthalmoplegia
Posterior column disease
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○ Lhermitte sign or barber chair syndrome due to increased mechano sensitivity
○ Truncal and gait ataxia : also seen in mets causing cord compression
○ Impaired conduction in dorsal spino cere -bellar tract may be a primar manifestation of epidural spinal cord compression-lower extremity dysmetria and gait ataxia.
○ Pt usually have thoracic spine compression due to selective vulnerability of spinocere bellar tract in thoracic spine to compres -sive ischemia
Posterior column disease
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Hemisection of the spinal cord( Brown sequard syndrome)
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Hemisection of the spinal cord( Brown sequard syndrome)
Loss of pain, temp C/L to the hemisection- interruption of crossed spino thalamic tract
Loss of proprioception – interruption of ascending fibers of posterior column
Spastic weakness due to interruption of descending cortico spinal tract
Segmental LMN signs and sensory changes at the level of lesion due to damage of the roots and anterior horn cells at the level of lesion
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INNERVATION OF AUTONOMIC NERVOUSSYSTEM
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Thank you BrainFor all you remember
What you forgot was my fault