solid state medical imaging: x-ray and endoscopy 2014 report by yole developpement

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Overview of the technical & economic requirements for Medical Imaging applications October 2014 Solid State Medical Imaging: X-Ray and Endoscopy SAMPLE The Medical Image Sensors market is expected to double over the next five years. M&A are increasing. Discover how Medical Imaging is being reshaped! Le Quartz - 75 cours Emile Zola - 69100 LYON-Villeurbanne Tel: +33 472 83 01 80 - Fax: +33 472 83 01 83 Web: www.yole.fr

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Solid State Medical Imaging: X-ray and Endoscopy

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Page 1: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

Overview of the technical & economic requirements for Medical Imaging applications

October 2014

Solid State Medical Imaging: X-Ray and Endoscopy

SAMPLEThe Medical Image Sensors market is expected to double over the next five years. M&A

are increasing. Discover how Medical Imaging is being reshaped!

Le Quartz - 75 cours Emile Zola - 69100 LYON-Villeurbanne

Tel: +33 472 83 01 80 - Fax: +33 472 83 01 83

Web: www.yole.fr

Page 2: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

© 2014 • 2Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.

Table of content

1) Executive Summary ………………...........................p.4

2) Introduction, Definitions & Methodology …….…p.16

3) What’s Happened in the Last Two Years?...........p.39

4) Medical Image Sensor technologies overview….p.13– CCD image sensors

– CMOS image sensors

– Amorphous silicon flat panels

– Technologies comparison

– Specificity of X-ray imaging

5) Medical Image Sensors Market Overview ...…….p.35– Global imaging market

o Forecasts in revenue/volume

– Endoscopy market

o Split by technology (CCD & CMOS)

o Forecasts in revenue/volume/wafer shipments

– X-ray imaging marketo Split by technology (CCD, CMOS and a-Si)

o Forecasts in revenue/volume/wafer shipments

– CCD medical image sensors market

o Forecasts in revenue /volume split by product category

– CMOS medical image sensors marketo Forecasts in revenue and in volume split by product

category

– a-Si flat panel sensors market

o Forecasts in revenue and in volume split by product

category

6) Market segmentation ....................................p.64– Market drivers by segment

– Technology positioning

7) Product categories description .....................p.72– Focus on endoscopy applications

o Rigid endoscopes

Market revenue/volume

Market drivers

Players

Technologies

o Flexible endoscopes

Market revenue/volume

Market drivers

Players

Technologies

o Camera pills

Market revenue/volume

Market drivers

Players

Technologies

o Disposable endoscopes

Market revenue/volume

Market drivers

Players

Technologies

-

Page 3: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

© 2014 • 3Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.

Table of content

– Focus on X-ray imagingo Dental X-ray imaging Market revenue/volume

Market drivers

Players

Technologies

o Medical X-ray imaging Market revenue/volume

Market drivers

Players

Technologies

8) Medical Image Sensors Supply Chain Analysis..p.267– Rigid endoscopes

– Flexible endoscopes

– Camera pills

– Disposable endoscopes

– X-ray intraoral detectors

– X-ray flat panel detectors

9) Medical Image Sensors Value Chain Analysis...p.279– Disposable endoscope value chain

– Flexible endoscope value chain

– Rigid endoscope value chain

– CMOS camera pill value chain

– A Si flat static panel detector value chain

– A Si flat dynamic panel detector value chain

– CMOS panel intra oral detector value chain

10) Medical Image Sensors Challenges….p.287

11) Summary and Conclusions………………p.299

Page 4: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

© 2014 • 4Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.

Some Companies Cited in the Report

AGFA, Alcon, Austria Microsystems, CMOSIS (Awaiba), BioVision Technologies LLC , Caeleste, CapsoVision Inc., Carestream Health, Circon, Cyber Medical,

Dongbu Hitek, e2v, EndoOptiks, Escalon, FiberTech, Fujifilm, Fujinon, General Electrics, GI View, Giotto, Given Imaging, GMM, Hamamatsu, Hitachi, Hologic, Hoya Life Sciences, Imix, IntroMedic, Intuitive Surgical ,Invendo Medical, ISDI,

Italray, Jinshan Group, Karl Storz, Konica Minolta, Medigus, Micro-Imaging Solutions, Olympus, ON semiconductor (Cypress), OSAT, VT & Aptina, Palodex,

Panasonic, Perkin Elmer (Dexela), Philips, Primax, Pyxalis, RF Systems labs, Richard Wolf, Samsung, Shimadzu, Siemens, Sony, STMicro, Stryker, Swissray,

Teledyne DALSA, Toshiba, TowerJazz, Trixell, True sense imaging, TSMC, Varian, Vatech Human ray, Villa, VIM’S, X-Fab, Ziehm Imaging…

Page 5: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

© 2014 • 5Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.

Medical Image SensorsScope of the report

• This report will focus exclusively on direct Imaging applications.

• Microscopy is excluded from that report because is hardly ever used in vivo, primarily it is used in vitro.

• Indirect imaging applications will not be developed in this report as their evolution rather relies on softwareprocessing optimization.

Direct Imaging / Hardware DependantIndirect Imaging / Software

Dependant

Microscopy Endoscopy X-Ray based methods MRIUltrasound

ImagingNuclear

Medicine

Stan

dal

on

e

DisposableCamera

pillsDisposable endoscopes

Re-usableFlexible

endoscopesRigid

endoscopes

X-Ray imagers for intra-oral

imagingX-Ray imagers for 3D & large area imaging

Doppler ultrasound

Integrated into a large system

MicroscopesX-Ray imagers for 2D extra-oral imaging

CTMRI syste

mPET Scan

Application

Optical Imaging X-ray Imaging

Page 6: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

© 2014 • 6Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.

Image Sensor Technologies by Market

The table below links applicative markets and Medical Image Sensor (MIS) technologies:

CCD MIS CMOS MIS A-Si MIS

Camera pillsmarket

X X

Disposable endoscopes market

X

Flexible endoscopes market

X X

Rigid endoscopes market

X X

intra-oral imagingmarket

X

X-ray 3D CBCT extra-oral imaging

X X X

2D extra-oralmarket

X

3D & large areamarket

X X X

En

do

sc

op

y

Ap

pli

ca

tio

n

X-R

ay I

ma

gin

g

Ap

pli

ca

tio

n

Page 7: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

© 2014 • 7Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.

Value Chain Analysis

Technology penetration per markets and market shares are provided.

Page 8: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

© 2014 • 8Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.

Market Forecast for equipment / sensorsIn value / volume / wafers shipments

Instruments Markets…

Sensors Markets…

…splited by Medical Image Sensors technologies

Page 9: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

© 2014 • 9Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.

Value Chain Analysis

Detailed Value Chains have been added

Page 10: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

© 2014 • 10Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.

Detailed Supply Chain

Updated supply chain are available for each

product category

Page 11: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

© 2014 • 11Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.

Supply Chain evolution is described

Our analysis on the supply chain evolution and the potential next targets are presented

Page 12: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

© 2014 • 12Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.

Technology TrendsX-Ray Imaging Technologies Overview

CCD Image

Intensified

Camera

a-Si FPD

CMOS FPD

• Three main components : 1. Scintillator to convert x-ray into visible

light

2. Fiber Optic Taper for mignification

3. CCD sensor for light to electron

conversion

• High resolution

• Buky, low field of viewCCD sensor

Fiber Optic Taper

Scintillator

X-Ray

ADC Processing

• Two components: 1. Scintillator to convert x-ray into visible

light

2. a-Si matrix array: passive pixels

(photodiodes convert light into electrons +

one TFT switch per pixel)

• Very large panel, simple, economical

• Low resolution, image lag, slow

X-Ray

Scintillator

a-Si array

• Two components: 1. Scintillator for x-ray to visible light

conversion

2. CMOS image sensor: active pixel

(photodiodes convert light into electrons +

several transistors per pixel convert charges

to voltage, on-pixel ADC & amplifier)

• High speed/resolution

• Limited size needs sensor tiling,

expensive

X-Ray

Scintillator

CMOS image

sensor

+

-

+

-

+

-

Page 13: Solid State Medical Imaging: X-ray and Endoscopy 2014 Report by Yole Developpement

© 2014 • 13Medical Imaging September 2014 Copyrights © Yole Développement SA. All rights reserved.

About The Author

Benjamin ROUSSEL

He is leading the MedTech activity (microfluidic and medical technologies) at Yole Développement. He holds a pharmacy diploma from the University Claude Bernard Lyon, complemented by a master degree in Technology and Innovation Management from EM Lyon Business School.Contact: [email protected]