metabolismo de alcohol

7/25/2019 Metabolismo de Alcohol

1/40

UNIVERSIDAD NACIONALAUTNOMA DE MXICOFACULTAD DE ESTUDIOS

SUPERIORES IZTACALA


2/40

Absorcin y ds!ino d"

#"co$o"E" cons%&o d" #"co$o" &'i(# 'or )*# or#" yds'%+s s )# #" !r#c!o di,s!i)o 'rinci'#"&n!"# #bsorcin s d# n " in!s!ino d",#do

L# #bsorcin s &di#n! di-%sin '#si)#


3/40

Ds'%+s d #bsorbrs n " in!s!inod",#do '#s# #" !orrn! s#n,%*no .

&in%!os ds'%+s y "# &/0i concn!r#cins#n,%*n# s d# n!r 12 # 32 &in%!os


4/40

META4OLISMO DE

ETANOL


5/40

MEOS d'ndin! d P5.2

E!#no" in$ib " &!#bo"is&o d -/rcos con co&'!ircon n(is d'ndin!s d" ci!ocro&o P5.2


6/40


7/40

In!rod%ccin E" !#no" s o0id# # #c!#"d$ido 'or &diod 1 sis!s n(i&/!icos6

78 E" sis! d "# #"co$o" ds$idro,n#s#9AD:; 9ci!oso"; d "# 8 E" sis! Microso" O0id#!i)o d" E!#no"9MEOS; 9REL? ci!ocro&o P5.2 >E7; 9.@>.=;8

18 E" sis! d "#s c#!#"#s#s 9'ro0isos;


8/40

M!#bo"is&o :'/!ico d"

E!#no"

E" 2= d" !#no" in,rido s &!#bo"i(# n "$*,#do 'or "#s n(is AD: y ALD:


9/40

E" #c!#"d$ido s o0id#do ##c!#!o 'or "# n(i

ds$idro,n#s# d" #c!#"d$ido9ALD:;8E" #c!#"d$ido s %n co&'%s!o#"!#&n! r#c!i)o y s !0ico


10/40

A"co$o" Ds$idro,n#s#L# AD: s "oc#"i(# 'r-rn!&n! n "ci!oso"8

Con)ir! " !#no" n #c!#"d$ido8R


11/40

Sis! o0id#!i)o

&icroso"8E" sis! MEOS s "oc#"i(# n "#scis!rn#s d" REL? s %n sis!

ind%cib" 'or " s%s!r#!o y s%'rinci'#" n(i s " ci!ocro&oP5.2@>E7 9CP>E7;8

E" $*,#do 'os " G= d" CP>E7!o!#" d" c%r'o8 T#&bi+n s!/'rsn! n " crbro y " '%"&n8


12/40

L# CP>E7 !in -c!o #c!i)#dor d'roc#rcin,nos co&o "# N@di&!i" ni!ros#&in# y dso")n!s or,/nicos co&o " !!r#c"or%ro d

c#rbono8Es %n# d "#s n(is


13/40

M!#bo"is&o :'/!ico d"

E!#no" 9MEOS; Nor"&n! " !#no" s &!#bo"i(#'r-rn!&n! 'or "# AD: $'/!ic# y n&nor c#n!id#d 'or " sis! MEOS y#


14/40

Sis! d c#!#"#s#L# c#!#"#s# s %n# n(i


15/40

Mc#nis&o d #ccinL# c#!#"#s# %!i"i(# %n &c#nis&oO>H CAT@F@OO: :>O


16/40

Es! 'r0ido d $irro sin!r&di#rio y s conoc co&oCo&'%s!o I? c%#ndo $#y 'oco'r0ido " co&'%s!o I '%d srrd%cido 'or " !#no"8 Un &'"o

d s!o s d# n " $*,#do


17/40

C%#ndo s in$ib " co&'%s!o I s $#c

s "n!o "# "i&in#cin d" !#no" 'or "o!#n!o c%#ndo $#y concn!r#cions d #"co$o",r#nds s!# n(i &'i(# # !r#b##ro0id#ndo #" #"co$o"


18/40

Consc%nci#s&!#b"ic#s d"

cons%&o d#"co$o"CADA RAMO DE ETANOL APORTA G87JCAL8


19/40

>= d" #"co$o" cons%&ido s "i&in#do

Rs!o s &!#bo"i(# n " $*,#do8

No '%d sr #"cn#doS %!i"i(# con Bns nr,+!icos8


20/40

Dsn%!ricin

DBcinci# d6

M!ionin#6 Po!nci# !r#ns-orcin d,r#s# d" $*,#do8

A,o!#&in!o d ni)"s d ,"%!#!in y

)i!#&in# A8M!#bo"is&o d riboK#bin#? 'irido0in#?Vi!8 C? Vi!8 D? J? !i#&in#? 47>


21/40

Ds$idro,n#s# A"co$"ic# NAD:

E0cso d o0id#cin $'/!ic# d !#no" ")#ndo ni)"sd NAD:

Cocin! "#c!ico'ir%)ico s ")#

nr# #cidosis

Rd%c "# c#'#cid#d d0cr!#r Ac8 rico

9$i'r%ric&i#; Crisis

o!os#


22/40

E")# @,"icro-os-#!o8 Ac8 r#sos

I&'id s*n!sis 'ro!ic#8 REDOX

Dis&in%cin d Ac8Pir)ico

9@; Prod%ccin :'/!ic# d #"b&in#?!r#ns-rrin#? "i'o'ro!*n#s8


23/40

Ac!#"d$*do S O0id#

Rd%ccin n &i!ocondri#s n

$'#!oci!os A%&n!o d NAD: n s#n,r?rd%c #c!i)id#d &i!ocondri#" d-os-ori"#cion o0id#!i)# y @ o0id#cin8


24/40

In!r#c!# con A/8 "%!#!ion

P#r!ici'# n ds!o0iBc#cion d r#dic#"s"ibrs

A%&n!# 'ro0id#cin 'or incr&n!o dNADP:

A%&n!# &!#bo"is&o b#s#"? y'rod%ccin d c#"or n " or,#nis&o8


25/40

A"!r#cin d Sis! in&%n8In&%nos%'rsin

InK%nci# d #"co$o" n CI

Es!r+s o0id#!i)o

Dis-%ncin d n%!rB"os8

A%&n!# " ris,o d c#ncro,+nsis


26/40

con "os&dic#&n!os


27/40

L#s in!r#ccions


28/40

ModiBc#cions n "

&!#bo"is&oSon "#s


29/40

D'rsin n SNCL#s in!r#ccions &/s i&'or!#n!s


30/40

F/rcosS*n!os

En-r&d#dsMdic#&n!os

9No&br ,n+rico;

A",%n#s d "#sr#ccions 'osib"ssi s &(c"#n con

#"co$o"

A"r,i#s? rs-r*os? ,ri' Lor#!#din# L!#r,o? ros?#%&n!o d" ris,o dsobrdosis8

Ansid#d y 'i"'si# C"on#('#&Di#('#&

L!#r,o? disn#8

In-ccions J!ocon#(o"M!ronid#(o"

T#


31/40

FACTORES PSICOLICOSPSIQUITRICOS8


32/40

Los -#c!ors 'sico",icos son "os #,n!s


33/40

In!rno Lo ,n+!ico8


34/40

Psico",ico 4## #%!os!i

S#!is-#cr "# c%riosid#d'ro'i#

Q%rr sc#'#r d "# r#"id#d


35/40

Problema psiquitrico primario

Prob"s d 'rc'cin y %icio id#s6d"ir#n!s? '#r#noids y #"%cin#cions8


36/40

Por "o


37/40

Co&orbi"id#dLos !r#s!ornos r"#cion#dos s di)idn n dos6Tr#s!ornos 'or cons%&o d s%s!#nci#sTr#s!ornos ind%cidos 'or s%s!#nci#s8

Prob" sobr "os !r#s!ornos dob"s $##%&n!#do8


38/40

Tr#s!ornos 'or cons%&o d

s%s!#nci#sD'ndnci#

Ab%so


39/40

Tr#s!ornos ind%cidos 'or

s%s!#nci#sIn!o0ic#cinD"iri%&

D&nci#

Tr#s!orno #&n+sico

Tr#s!orno #-c!i)o

Tr#s!orno 'sic!ico

Tr#s!orno #nsiosoTr#s!orno s0%#"

Tr#s!orno d" s%o


40/40

4ib"io,r#-*#:rn/nd( Tri#n# M#n%"? A"!r#cions M!#b"ic#s n "#"co$o"is&o? Ins!i!%!o d N%!ricin :i,in d#"i&n!os? R)is!# C%b#n# A"i&n!o y N%!ricin 73372

ARAN? C8 MIQUEL? M8 CORREA? M8 SANC:IS@SEURA?

C8 A"co$o" y &!#bo"is&o $%no? Adiccions? >22>74io

metabolismo de alcohol

Documents