pcca exclusive base dosage form(s) ideal in formulations ......• quick absorption, smooth texture,...

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Eclusive PCCA Bases Quick-Reference Poster | © PCCA 2019 See PCCA Document #99650 for a short booklet highlighting PCCA’s most popular bases. PCCA Exclusive Base Dosage Form(s) Ideal in Formulations For Common APIs Example Formulas Atrevis Hydrogel PCCA #30-4986 Superior testosterone delivery backed up by independent testing Alcohol-free for better stability and less irritation Quick absorption, smooth texture, and no greasy residue Topical gel Testosterone replacement Testosterone • PCCA Formula #12674 Testosterone 0.5% to 20% (Bracketed) • PCCA Formula #12676 Testosterone 5%/Anastrozole 0.05%/HCG 500 U/Gm • PCCA Formula #12681 Testosterone 5%/Finasteride 0.1% Clarifying Base PCCA #30-4845 Topical base that moisturizes and supports healthy skin May improve the appearance of red, blotchy skin • Easily accommodates antimicrobials, benzoyl peroxide, tretinoin, alpha and beta hydroxy acids, and more Topical cream • Acne/problem skin • Rosacea • Aging skin prone to acne • Benzoyl peroxide • Salicylic acid • Tretinoin • Erythromycin • PCCA Formula #11800 Clindamycin 1%/Benzoyl Peroxide 5%/Superoxide Dismutase 0.5%/Vitamin D3 0.5% • PCCA Formula #11710 Niacinamide 5%/Glycosaminoglycans 5%/Dimethyl Sulfone 2%/Biotin 0.2% • PCCA Formula #11713 Sodium Hyaluronate 0.05%/Collagen/Aloe Vera/Glycolic Acid/Vitamin E Lipoderm ® PCCA #30-3338 Validated vehicle for deep-penetrating topical formulations and transdermal formulations Patented transdermal technology backed by numerous peer- reviewed studies Over 15 formulas with extended beyond-use dates Transdermal cream • Acute or chronic pain • Anxiety • Nausea • Veterinary medicine • Analgesics and anesthetics • Anxiolytics • Antiemetics • PCCA Formula #10835 Ketamine HCl 5%/Gabapentin 10%/Clonidine HCl 0.2%/ Baclofen 2% • PCCA Formula #12375 Promethazine HCl 12.5 mg/Gm to 25 mg/Gm Topical (Bracketed) • PCCA Formula #12373 Methimazole 2.5 mg/0.1 Gm to 10 mg/0.1 Gm (Bracketed) Lipoderm ActiveMax ® PCCA #30-4482 Developed for APIs in salt form at high concentrations Uses the same patented transdermal system as Lipoderm • Eight formulas with extended beyond-use dates APIs that are in a salt form (e.g., Cl, Na) • PCCA Formula #10287 Diclofenac Sodium 5%/Gabapentin 5%/Amitriptyline HCl 2% • PCCA Formula #11090 Flurbiprofen 10%/Baclofen 2%/Cyclobenzaprine HCl 2%/ Tetracaine 2% • PCCA Formula #10673 Clomiphene Citrate 5% LoxaSperse ® PCCA #30-4701 Powder base that provides topical delivery to the nasal and sinus cavities when reconstituted Reduces particle size and increases dispersibility and solubility of APIs Easy to store and carry with prolonged beyond-use date in powder/capsule preparation • Commonly compounded with PCCA XyliFos ® (PCCA #30-4894) Nasal nebulization and irrigation Chronic sinus conditions • Antifungals • Antibiotics • Corticosteroids • PCCA Formula #12850 Mupirocin 5 mg/Budesonide 0.6 mg Capsules Size #1 • PCCA Formula #12855 Tobramycin 20 mg/Budesonide 0.6 mg Capsules Size #1 • PCCA Formula #12857 Clindamycin 30 mg/Budesonide 0.6 mg Capsules Size #1 LoxOral ® PCCA #30-4774 Powder base that makes capsules easier to prepare and saves time Reduces static, making micronized powders easier to work with Provides even distribution and improved dissolution of APIs Oral capsules • Oral hormone replacement therapy (HRT) • General systemic medication • Veterinary medicine • Progesterone • Estriol • Estradiol • PCCA Formula #11296 Estriol/Estradiol [80%/20%] 2 mg/Progesterone 100 mg/ Testosterone 0.5 mg/DHEA 25 mg Slow Release Capsules Size #0 • PCCA Formula #10797 Progesterone 100 mg Slow Release Capsules Size #1 • PCCA Formula #10805 Naltrexone HCl 0.5 mg Capsules Size #1 MucoLox PCCA #30-4782 Unique liquid-gel base that adheres to mucosa up to 24 times longer than other products Increases contact time between APIs and mucosa Can be diluted with water to adjust viscosity • Commonly compounded with VersaBase ® Gel (PCCA #30-3656) to create vaginal gels • Oral, vaginal or rectal gel • Oral mouthwash or spray • Esophageal/gut suspension • Vaginal HRT • Oral mucositis • Proctitis • Hormones • Anesthetics • Corticosteroids • PCCA Formula #11115 Estriol 0.05% Vaginal Gel • PCCA Formula #12066 Stanford Modified Oral Rinse (Lab Study) • PCCA Formula # 12228 Budesonide 1 mg/10 mL to 2 mg/10 mL Oral Suspension (Bracketed) PracaSil ® -Plus PCCA #30-4655 Anhydrous topical silicone base that provides superior moisturization and protection Contains pracaxi oil that is rich in skin-friendly fatty acids and lipids • Promotes a soothing and nurturing environment Topical gel • All scars, including new, old, keloid, hypertrophic and surgical • Burns and diabetic wounds • Stretch marks • Corticosteroids and antioxidants • Anesthetics and NSAIDs • Antibiotics and antifungals • PCCA Formula #10826 Fluocinolone Acetonide 0.01%/Hydroquinone 4%/ Tretinoin 0.05% • PCCA Formula #10419 Tretinoin 0.1% • PCCA Formula #10234 Tamoxifen Citrate 0.1%/Tranilast 1%/Caffeine Citrated 0.1%/Lipoic Acid 0.5% SuspendIt ® PCCA #30-4825 Oral-suspension base that thins when shaken and thickens when standing Minimizes sedimentation and allows for rapid redispersion of APIs with agitation • All-natural sweetness derived from monk fruit Oral suspension • Pediatric compounding • Hospice and oncology • Veterinary medicine • Proton-pump inhibitors • Corticosteroids • Anticonvulsants • PCCA Formula #11262 Omeprazole 2 mg/mL to 10 mg/mL (Bracketed) • PCCA Formula #12539 Phenobarbital 1 mg/mL to 50 mg/mL (Bracketed) • PCCA Formula #5374 Cisapride 10 mg/mL (Vet) VersaBase ® Cream PCCA #30-3641 Elegant yet durable topical cream that is stable over a broad pH range (3.5-12) • Noncomedogenic, hypoallergenic, nonirritating and odor-free Formulated without oil, petrolatum, parabens and propylene glycol • Topical cream • Vaginal cream • Hormone Replacement Therapy (HRT) • General topical compounding • Estriol • Estradiol • Progesterone • PCCA Formula #12116 Estriol/Estradiol [50%/50%] 0.25 mg/0.5 Gm to 1 mg/0.5 Gm Topical Cream (Bracketed) • PCCA Formula #12114 Progesterone 10 mg/Gm to 100 mg/Gm Topical Cream (Bracketed) • PCCA Formula #12227 Amitriptyline HCl 0.25% to 5% Vaginal Cream (Bracketed) XemaTop PCCA #30-4891 Topical base containing a skin-friendly blend of boswellic acid, avenanthramides from oats, phosphatidylglycerol and film formers Moisturizes while nourishing the skin’s structural integrity May improve the appearance of red, irritated, flaky skin Topical cream • Eczema • Psoriasis • Xerosis (dry skin) • Corticosteroids • Vitamins B, D and E, and derivatives • Zinc pyrithione • PCCA Formula #12371 Cyanocobalamin 0.07% to 1% (Bracketed) • PCCA Formula #12374 Pentoxifylline 5% to 15% (Bracketed) • PCCA Formula #11788 Zinc Pyrithione 0.2%/Clobetasol Propionate 0.05%/ Cyanocobalamin 0.07% = FormulaPlus BUD Study Exclusive PCCA Bases Quick-Reference Poster | For studies on these bases, visit pccarx.com/science.

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Page 1: PCCA Exclusive Base Dosage Form(s) Ideal in Formulations ......• Quick absorption, smooth texture, and no greasy residue Topical gel Testosterone replacement Testosterone • PCCA

Eclusive PCCA Bases Quick-Reference Poster | © PCCA 2019See PCCA Document #99650 for a short booklet highlighting PCCA’s most popular bases.

PCCA Exclusive Base Dosage Form(s) Ideal in Formulations For Common APIs Example Formulas

Atrevis™ HydrogelPCCA #30-4986

• Superior testosterone delivery backed up by independent testing

• Alcohol-free for better stability and less irritation

• Quick absorption, smooth texture, and no greasy residue

Topical gel Testosterone replacement Testosterone

• PCCA Formula #12674 Testosterone 0.5% to 20% (Bracketed)

• PCCA Formula #12676 Testosterone 5%/Anastrozole 0.05%/HCG 500 U/Gm

• PCCA Formula #12681 Testosterone 5%/Finasteride 0.1%

Clarifying Base™

PCCA #30-4845

• Topical base that moisturizes and supports healthy skin

• May improve the appearance of red, blotchy skin

• Easily accommodates antimicrobials, benzoyl peroxide, tretinoin, alpha and beta hydroxy acids, and more

Topical cream

• Acne/problem skin

• Rosacea

• Aging skin prone to acne

• Benzoyl peroxide

• Salicylic acid

• Tretinoin

• Erythromycin

• PCCA Formula #11800 Clindamycin 1%/Benzoyl Peroxide 5%/Superoxide Dismutase 0.5%/Vitamin D3 0.5%

• PCCA Formula #11710 Niacinamide 5%/Glycosaminoglycans 5%/Dimethyl Sulfone 2%/Biotin 0.2%

• PCCA Formula #11713 Sodium Hyaluronate 0.05%/Collagen/Aloe Vera/Glycolic Acid/Vitamin E

Lipoderm®

PCCA #30-3338

• Validated vehicle for deep-penetrating topical formulations and transdermal formulations

• Patented transdermal technology backed by numerous peer-reviewed studies

• Over 15 formulas with extended beyond-use datesTransdermal cream

• Acute or chronic pain

• Anxiety

• Nausea

• Veterinary medicine

• Analgesics and anesthetics

• Anxiolytics

• Antiemetics

• PCCA Formula #10835 Ketamine HCl 5%/Gabapentin 10%/Clonidine HCl 0.2%/ Baclofen 2%

• PCCA Formula #12375 Promethazine HCl 12.5 mg/Gm to 25 mg/Gm Topical (Bracketed)

• PCCA Formula #12373 Methimazole 2.5 mg/0.1 Gm to 10 mg/0.1 Gm (Bracketed)

Lipoderm ActiveMax®

PCCA #30-4482

• Developed for APIs in salt form at high concentrations

• Uses the same patented transdermal system as Lipoderm

• Eight formulas with extended beyond-use dates

APIs that are in a salt form (e.g., Cl, Na)

• PCCA Formula #10287 Diclofenac Sodium 5%/Gabapentin 5%/Amitriptyline HCl 2%

• PCCA Formula #11090 Flurbiprofen 10%/Baclofen 2%/Cyclobenzaprine HCl 2%/Tetracaine 2%

• PCCA Formula #10673 Clomiphene Citrate 5%

LoxaSperse®

PCCA #30-4701

• Powder base that provides topical delivery to the nasal and sinus cavities when reconstituted

• Reduces particle size and increases dispersibility and solubility of APIs

• Easy to store and carry with prolonged beyond-use date in powder/capsule preparation

• Commonly compounded with PCCA XyliFos® (PCCA #30-4894)

Nasal nebulization and irrigation Chronic sinus conditions

• Antifungals

• Antibiotics

• Corticosteroids

• PCCA Formula #12850 Mupirocin 5 mg/Budesonide 0.6 mg Capsules Size #1

• PCCA Formula #12855 Tobramycin 20 mg/Budesonide 0.6 mg Capsules Size #1

• PCCA Formula #12857 Clindamycin 30 mg/Budesonide 0.6 mg Capsules Size #1

LoxOral®PCCA #30-4774

• Powder base that makes capsules easier to prepare and saves time

• Reduces static, making micronized powders easier to work with

• Provides even distribution and improved dissolution of APIs

Oral capsules

• Oral hormone replacement therapy (HRT)

• General systemic medication

• Veterinary medicine

• Progesterone

• Estriol

• Estradiol

• PCCA Formula #11296 Estriol/Estradiol [80%/20%] 2 mg/Progesterone 100 mg/Testosterone 0.5 mg/DHEA 25 mg Slow Release Capsules Size #0

• PCCA Formula #10797 Progesterone 100 mg Slow Release Capsules Size #1

• PCCA Formula #10805 Naltrexone HCl 0.5 mg Capsules Size #1

MucoLox™

PCCA #30-4782

• Unique liquid-gel base that adheres to mucosa up to 24 times longer than other products

• Increases contact time between APIs and mucosa

• Can be diluted with water to adjust viscosity

• Commonly compounded with VersaBase® Gel (PCCA #30-3656) to create vaginal gels

• Oral, vaginal or rectal gel

• Oral mouthwash or spray

• Esophageal/gut suspension

• Vaginal HRT

• Oral mucositis

• Proctitis

• Hormones

• Anesthetics

• Corticosteroids

• PCCA Formula #11115 Estriol 0.05% Vaginal Gel

• PCCA Formula #12066 Stanford Modified Oral Rinse (Lab Study)

• PCCA Formula # 12228 Budesonide 1 mg/10 mL to 2 mg/10 mL Oral Suspension

(Bracketed)

PracaSil®-PlusPCCA #30-4655

• Anhydrous topical silicone base that provides superior moisturization and protection

• Contains pracaxi oil that is rich in skin-friendly fatty acids and lipids

• Promotes a soothing and nurturing environment

Topical gel

• All scars, including new, old, keloid, hypertrophic and surgical

• Burns and diabetic wounds

• Stretch marks

• Corticosteroids and antioxidants

• Anesthetics and NSAIDs

• Antibiotics and antifungals

• PCCA Formula #10826 Fluocinolone Acetonide 0.01%/Hydroquinone 4%/Tretinoin 0.05%

• PCCA Formula #10419 Tretinoin 0.1%

• PCCA Formula #10234 Tamoxifen Citrate 0.1%/Tranilast 1%/Caffeine Citrated 0.1%/Lipoic Acid 0.5%

SuspendIt®

PCCA #30-4825

• Oral-suspension base that thins when shaken and thickens when standing

• Minimizes sedimentation and allows for rapid redispersion of APIs with agitation

• All-natural sweetness derived from monk fruit

Oral suspension

• Pediatric compounding

• Hospice and oncology

• Veterinary medicine

• Proton-pump inhibitors

• Corticosteroids

• Anticonvulsants

• PCCA Formula #11262 Omeprazole 2 mg/mL to 10 mg/mL (Bracketed)

• PCCA Formula #12539 Phenobarbital 1 mg/mL to 50 mg/mL (Bracketed)

• PCCA Formula #5374 Cisapride 10 mg/mL (Vet)

VersaBase® CreamPCCA #30-3641

• Elegant yet durable topical cream that is stable over a broad pH range (3.5-12)

• Noncomedogenic, hypoallergenic, nonirritating and odor-free

• Formulated without oil, petrolatum, parabens and propylene glycol

• Topical cream

• Vaginal cream

• Hormone Replacement Therapy (HRT)

• General topical compounding

• Estriol

• Estradiol

• Progesterone

• PCCA Formula #12116 Estriol/Estradiol [50%/50%] 0.25 mg/0.5 Gm to 1 mg/0.5 Gm Topical Cream (Bracketed)

• PCCA Formula #12114 Progesterone 10 mg/Gm to 100 mg/Gm Topical Cream (Bracketed)

• PCCA Formula #12227 Amitriptyline HCl 0.25% to 5% Vaginal Cream (Bracketed)

XemaTop™

PCCA #30-4891

• Topical base containing a skin-friendly blend of boswellic acid, avenanthramides from oats, phosphatidylglycerol and film formers

• Moisturizes while nourishing the skin’s structural integrity

• May improve the appearance of red, irritated, flaky skin

Topical cream

• Eczema

• Psoriasis

• Xerosis (dry skin)

• Corticosteroids

• Vitamins B, D and E, and derivatives

• Zinc pyrithione

• PCCA Formula #12371 Cyanocobalamin 0.07% to 1% (Bracketed)

• PCCA Formula #12374 Pentoxifylline 5% to 15% (Bracketed)

• PCCA Formula #11788 Zinc Pyrithione 0.2%/Clobetasol Propionate 0.05%/Cyanocobalamin 0.07%

= FormulaPlus™ BUD StudyExclusive PCCA Bases Quick-Reference Poster | For studies on these bases, visit pccarx.com/science.