Medical Scientist Training Program (MSTP)

Annual Report 2014-2015

College of Graduate Studies College of Medicine

College of Graduate Studies College of Meicine

MEDICAL SCIENTIST TRAINING PROGRAM Steering Committee 2014-2015

Dr. Perry V. Halushka Director, MSTP Distinguished University Professor Dr. Robin Muise-Helmericks Associate Director, MSTP Associate Professor of Regenerative Medicine and Cell Biology Ms. Amy Connolly Assistant Director, MSTP Dr. John M. Arthur Professor of Medicine/Nephrology Dr. Steven L. Carroll Professor & Chair, Pathology & Laboratory Medicine Dr. James A. Cook Professor of Neurosciences Dr. Benjamin Clyburn Associate Professor, Medicine Associate Dean for Graduate Medical Education Faculty Development, College of Medicine Dr. Christopher Davies Professor of Biochemistry & Molecular Biology Dr. Deborah Deas Senior Associate Dean for Medical Education, College of Medicine Professor, Psychiatry & Behavioral Medicine Dr. Scott Eblen Associate Professor of Cell & Molecular Pharmacology Dr. Carol Feghali-Bostwick Kitty Trask Holt Endowed Chair Professor, Rheumatology & Immunology

Dr. Donna Kern Associate Professor, Family Medicine Associate Dean for Curriculum in the Clinical Sciences, College of Medicine Dr. Michael Kern Professor of Regenerative Medicine and Cell Biology Dr. Viswanathan Ramakrishnan Professor, Biostatistics & Epidemiology Dr. Don Rockey Professor and Chair of Medicine Dr. Baerbel Rohrer Professor of Neurosciences Dr. Cynthia Schandl Associate Professor of Pathology & Laboratory Medicine Dr. Rick Schnellmann Professor & Chair of Drug Discovery & Biomedical Sciences Dr. Joann Sullivan Assistant Dean for Extramural Program Development Dr. Stephen Tomlinson Professor of Microbiology & Immunology Dr. Graham Warren Associate Professor of Radiation Oncology Dr. Michael Yost Associate Professor of Surgery Brandon Bentzley MSTP Student Representative

College of Graduate Studies College of Medicine

MEDICAL SCIENTIST TRAINING PROGRAM COMMITTEES

2014-2015 Progress Committee Dr. Perry Halushka Dr. Robin Muise-Helmericks

Scholarship Committee Dr. Perry Halushka Dr. Robin Muise-Helmericks

Recruitment Committee Dr. Perry Halushka Dr. William Conway Dr. James Cook Dr. Melissa Cunningham Dr. Scott Eblen Dr. Carol Feghali-Bostwick Dr. Victoria Findlay Dr. Elizabeth Garrett-Mayer Dr. Michael Kern Dr. Yiannis Koutalos Dr. Amanda LaRue Dr. Robin Muise-Helmericks Dr. Arthur Riegel Dr. Baerbel Rohrer Dr. Cynthia Schandl Dr. Graham Warren Dr. Michael Yost Mr. Robert Cameron Mr. G. Russell Glenn Mr. Daniel Herr Mrs. Jamie Mills Mr. Daniel Neitzke Mr. Ken Noguchi Mr. Douglas Roberts-Wolfe Ms. Katelyn Williams Dr. Cynthia Wright – Ex-officio Dr. Deborah Deas – Ex-officio Dr. Donna Kern – Ex-officio Ms. Amy Connolly – Ex-officio Ms. Joan Graesch – Ex-officio

Seminar Committee Mr. Jacob Bowers Mr. David Hartmann Mr. Daniel Herr Representative to Graduate Council Mrs. Jamie Mills

College of Graduate Studies College of Medicine

MEDICAL SCIENTIST TRAINING PROGRAM STUDENTS

MSTP Matriculation Students Date Advisor Undergraduate School Ali Alawieh 6/13 Dr. S. Tomlinson American University of Beirut Joseph Alge 6/10 Dr. J. Arthur Wofford University/MUSC Obaidallah Aseem 6/06 Dr. S. Argraves Morehouse College Sagar Bajpai 6/15 Dr. G. Warren University of Maryland Baltimore County Tiffany Baker 6/09 Dr. L. Cunningham College of Charleston/MUSC Fahmin Basher 6/08 Dr. J. Wu University of South Carolina Thomas Beckham 6/07 Dr. J. Norris Clemson University Brandon Bentzley 6/09 Dr. G. Aston-Jones College of New Jersey-Trenton Krishna Bharani 6/13 Dr. L. Granholm Loyola University Jennifer Blakely 6/07 Dr. C. Beeson Erskine College Daniel Bonthius 7/15 Dr. H. Yao Wartburg College Jacob Bowers 6/11 Dr. C. Paulos University of Utah Laura Briggs 7/08 Dr. A. Wessels University of Florida Robert Cameron 5/11 Dr. R. Schnellmann/ Davidson College Dr. Y. Peterson Ying Chao 8/14 Dr. T. Jhou University of California San Diego Vivian Chioma 6/14 Dr. P. Kalivas University of Maryland Baltimore County Stewart Cox 7/15 Dr. B. Froeliger University of Colorado Boulder Mohammad Dahrouj 6/10 Dr. C. Crosson American University of Beirut Mohammed Dany 6/13 Dr. B. Ogretmen American University of Beirut Danielle Desjardins 6/11 Dr. Z. Ablonczy Boston University Maya Eid 6/15 Dr. T. Jhou American University of Beirut George Russell Glenn 8/10 Dr. J. Helpern/ Wofford University Dr. J. Jensen David Hartmann 7/12 Dr. A. Shih New College of Florida Daniel Herr 6/11 Dr. D. Menick University of Scranton Nathaniel Jensen 6/13 Dr. H. Cheung Brigham Young University Christopher B Johnson 6/09 Dr. D. Cole University of North Carolina-Chapel Hill Rebecca Knackstedt 6/08 Dr. M. Wargovich Denison University Hannah Knochelmann 8/15 TBA Notre Dame Craig Kutz 6/10 Dr. P. Woster Minnesota State University Moorhead Hyunwoo Tony Kwon 8/14 Dr. Z. Li University of Toronto Anthony Leonard 1/07 Dr. B. Rohrer Emory & Henry Danielle Clark Lowe 6/09 Dr. I. Singh/ Marshall University Dr. D. Jenkins Sarah Tucker Marrison 6/08 Dr. J. Norris Yale University Ahmad Mashmoushi 7/07 Dr. J. Oates American University of Beirut Allison Meadows 8/15 TBA University of Virginia Jamie Mills 6/11 Dr. S. Ethier California State University-Chico Keely Morris 6/06 Dr. S. Tomlinson Cal Tech Christopher Mullins 6/15 Dr. C Hanlon University of North Carolina Chapel Hill

Daniel Neitzke 6/10 Dr. D. Cole/ University of Virginia Dr. M. Rubinstein Ken Noguchi 5/12 Dr. P. Howe Kenyon College Elizabeth Ogunrinde 6/14 Dr. G. Gilkeson Florida State University Shikha Patel 6/13 Dr. B. Ogretmen University of South Carolina Sanket Pattanaik 6/13 Dr. M. Yost Cornell University Winston Plunkett 5/14 Dr. Z. Ablonczy University of Virginia Saleh Rachidi 6/10 Dr. Z. Li American University of Beirut Douglas Roberts-Wolfe 6/11 Dr. P. Kalivas Hampshire College Sarah Brice Russo 6/10 Dr. A. Cowart Clemson University/MUSC Jennifer Scott 8/09 Dr. G. Gilkeson University of Central Florida Joshua Smith 6/08 Dr. R. Schnellmann Wofford College Erik Strungs 6/09 Dr. R. Gourdie/ University of Minnesota-Twin Cities Dr. L. Luttrell Alton Sutter 6/07 Dr. K. Chavin College of Charleston Catherine Svetcharnik 5/15 Dr. C. Feghali-Bostwick University of Colorado Ralph Tanios 6/15 Dr. S. Carroll American University of Beirut Joseph Taylor 6/07 Dr. M. George Davidson College Danh Tran 6/13 Dr. S. Nadig University of California-Los Angeles Jonathan Turner 6/13 Dr. C. Davies West Virginia University Abigail Washispack 6/12 Dr. J. Jones University of Arkansas Ft. Smith Shannon Weber 7/15 Dr. S. Carroll University of Richmond Ryan Whitaker 6/08 Dr. R. Schnellmann University of Iowa Melanie Wiley 7/15 Dr. T. Jhou University of Maryland Baltimore County Katelyn Williams 6/12 Dr. B. Ogretmen University of Maryland Baltimore County Brandon Young 6/13 Dr. C. Davies University of Maryland Baltimore County Xiaoyi Zhang 6/08 Dr. K. Kirkwood University of South Carolina

*Deceased

Current Positions of MUSC MSTP Graduates (1982-2015)

MSTP Graduate Date Residency Current Position Samuel E. Gandy, III, MD, PhD

1982 Cornell University

Mount Sinai Professor of Alzheimer’s Research, Professor of Neurology & Psychiatry, Icahn School of Medicine at Mount Sinai

Geoffrey E. Renk, MD, PhD

1986 UCLA President, Charleston Emergency Services, Charleston, SC

Robert P. Aftring, MD, PhD 1987 Beth Israel Senior Global Program Head / Vice President, Established Medicines, Novartis Pharmaceuticals Corporation

Charles F. Burant, MD, PhD

1987 University of California San Francisco

Professor of Internal Medicine, Robert C. & Veronica Atkins Professor of Metabolism, Director of the Metabolomics and Obesity Center, University of Michigan Health System

*Kevin D. Ballard, MD, PhD 1989 Baylor College of Medicine

Deceased

Richard L. Griffith, MD, PhD

1989 University of Virginia Hospital

Practice of Internal Medicine/Immunology, Marietta, GA

*Stanley A. Katz, MD, PhD 1989 Vanderbilt University

Deceased

Margaret O. Sowell, MD, PhD

1990 Brigham and Women's Hospital

Medical Director, Global Clinical Safety and Pharmacovigilance, GlaxoSmithKline Pharmaceuticals

Richard H. Peters, MD, PhD

1991 Massachusetts General Hospital

Senior Vice President and Head of Rare Diseases at Genzyme, a Sanofi Company

N. Carolyn Schanen, MD, PhD

1991 Stanford University

Director, Center for Applied Clinical Genomics, and Principal Research Scientist & Head, Human Genetics Research Laboratory, Nemours Biomedical Research, Alfred I. DuPont Hospital for Children, Wilmington, DE; Associate Professor of Pediatrics, Thomas Jefferson University; Adjunct Associate Professor of Biological Sciences, University of Delaware

Keith A. Coffee, MD, PhD 1992 Vanderbilt University

Vice President, Scientific Affairs, PRA International

*Deceased

Stephen R. Murray, MD, PhD

1992 University of California San Francisco

Senior Medical Officer, Global Alliance for TB Drug Development, New York, NY

Jeffery L. Twiss, MD, PhD 1992 Stanford University

Professor and Head, Biology Department, Drexel University, Philadelphia, PA (2009-13); SmartState Endowed Chair in Neurotherapeutics and Professor of Biological Sciences, University of South Carolina, Columbia (eff. July 1, 2013)

William Oehlenschlager, MD, PhD

1993 Case Western Reserve University

Clinical Assistant Professor of Pediatrics, Ohio University College of Medicine; Practice of Pediatrics, Wadsworth OH

C. Richard Ross, MD, PhD 1993 Johns Hopkins University

Practice of Emergency Medicine, Modesto, CA

Kendrick A. Shunk, MD, PhD

1993 University of Chicago

Associate Professor of Medicine, University of California-San Francisco, and Director of Interventional Cardiology and Catheterization Laboratory Research, San Francisco VA Medical Center

Charles J. Beischel, MD, PhD

1994 Medical University of South Carolina

Clinical Assistant Professor of Ophthalmology, MUSC

J. Bryan Hill, MD, PhD 1995 Baylor University Assistant Professor of Clinical Pediatrics, University of South Carolina School of Medicine/Greenville Health System Children’s Hospital; Special Care Pediatric Center, Anderson, SC

Charles T. Ivester, MD, PhD

1996 University of Utah

Practice of Pulmonary, Critical Care and Sleep Medicine, Ogden, UT

Timothy C. Ball, MD, PhD 1997 Bowman Gray Assistant Professor of Medicine and Medical Director, Cardiac Catheterization Laboratory, Virginia Tech University Carilion School of Medicine and Research Institute, Roanoke, VA

Bradley S. Miller, MD, PhD 1997 Mayo Clinic Associate Professor of Pediatrics, Division of Pediatric Endocrinology, University of Minnesota

Kimberly V. Barnes, MD, PhD

1998 University of Chicago

Private Practice, Biloxi, MS

*Deceased

Gloria J. Bullock Morris, MD, PhD

1998 Thomas Jefferson University

Hematology & Oncology Associates of Central New York, Syracuse, NY

Charles E. Hill, MD, PhD 1998 Emory University Associate Professor of Pathology & Laboratory Medicine, and Director of the Molecular Diagnostics Laboratory, Emory University School of Medicine

Ana Maria Ibrado, MD, PhD

1998 Johns Hopkins University

Medical Director, Stroke Center and Clinical Decision Unit, Providence Hospital, Washington, DC

John H. Cleator, MD, PhD 1999 Cleveland Clinic Assistant Professor of Medicine (Cardiology) and Pharmacology (dual appt), Director of the Experimental Angiographic Laboratory, and Director of Interventional Cardiology Research, Vanderbilt University

Michel A. Makhlouf, MD, PhD

1999 University of Pittsburgh Magee Women's Hospital

Senior Attending Physician, OB/Gyn, Sidra Medical and Research Center, Doha, Qatar/Adjunct, Weil Cornell Med College-Qatar

Cynthia A. Schandl, MD, PhD

1999 Medical Univ. of South Carolina

Associate Professor of Pathology & Laboratory Medicine, and Director of Processed Biospecimen Services and Medical Director of Cytogenetics and Molecular Pathology, MUSC

Keith T. Borg, MD, PhD 2000 University of Cincinnati

Associate Professor, Emergency Medicine, Chief, Division of Pediatric Emergency Medicine, Interim Division Chief of Child Abuse Pediatrics, MUSC

Justin P. Favaro, MD, PhD 2000 University of Texas, Dallas Southwestern Medical Center

Assistant Consulting Professor, Department of Medicine, Duke University; Practice of Hematology Oncology

Kim M. Huffman, MD, PhD 2000 Duke University Assistant Professor of Medicine, Division of Rheumatology, Duke University Medical Center/ Staff Physician, Physical Medicine & Rehabilitation, Durham VA Medical Center

Antoine A. Makhlouf, MD, PhD

2000 University of Virginia

Practice of Urology, Houston and Sugar Land, TX

*Deceased

Donald C. Shields, MD, PhD

2000 UCLA Assistant Professor of Neurosurgery, George Washington University Medical Center

Kristie B. Blade, MD, PhD 2001 University of Washington

Practice of Internal Medicine in Lynwood, WA; affiliated with Virginia Mason Medical Center

Mark (Horney) Jameson, MD, PhD

2001 University of Virginia

Assistant Professor of Otolaryngology-Head & Neck Surgery, University of Virginia Health System

Chad E. Hudson, MD, PhD 2001 University of Maryland

Practice of Obstetrics & Gynecology, Hagerstown, MD

Deanne L. King, MD, PhD 2002 University of Arkansas

Practice of Otolaryngology, Little Rock, AR

Richard A. Walgren, MD, PhD

2002 Washington University

Medical Fellow and Medical Director, Oncology Clinical Development, Eli Lilly, Indianapolis, IN

Joseph R. Kelley, MD, PhD 2003 Medical College of Virginia

Practice of Radiation Oncology, Wichita, KS

Stewart M. Knoepp, MD, PhD

2003 Massachusetts General Hospital/Harvard

Assistant Professor of Pathology, University of Michigan

Bryce A. Nelson, MD, PhD 2003 Vanderbilt University

Associate Professor of Clinical Pediatrics, University of South Carolina School of Medicine; Adjunct Faculty, Virginia College of Osteopathic Medicine, Spartanburg, SC; Chairman, IRC-B, Greenville Hospital System Medical Director, Division of Pediatric Endocrinology & Diabetes Program, Greenville Hospital System

Christopher D. Willey, MD, PhD

2003 Vanderbilt University

Associate Professor, Radiation Oncology, Director of Kinome Core, University of Alabama Birmingham

Scott P. Commins, MD, PhD

2004 University of Virginia

Assistant Professor of Medicine and Pediatrics (dual appt), University of Virginia

Christopher A. Wells, MD, PhD

2004 Vanderbilt University

Cardiologist, American Family Care/Veterans Health Administration, Nashville, TN

Ralph J. Barker, MD, PhD 2005 MUSC/Surgery Resident 2005 MUSC Private Practice, Bradenton Trauma Surgical Group, Bradenton, FL

Kevin Becker, MD, PhD 2005 Yale Assistant Professor of Neurology, Yale University School of Medicine

*Deceased

Michael L. Bernard, MD, PhD 2005 Vanderbilt University/Internal Medicine Resident

2005 Vanderbilt University

Cardiac Electrophysiologist, Ochsner Clinic, New Orleans, LA

Christopher V. Crosby, MD, PhD

2005 Emory University Clinical Assistant Professor of Dermatology, University of California-San Diego

Michelle B. Crosby, MD, PhD

2005 Emory University Clinical Instructor of Ophthalmology, University of California-San Diego

Ron J. Feldman, MD, PhD 2005 Cleveland Clinic Assistant Professor of Dermatology, Emory University School of Medicine

Joshua M. Hubbard, MD, PhD

2005 University of Virginia

Asheville Radiology Associates, Asheville, NC

Benjamin J. Pettus, MD, PhD

2005 Washington University, St. Louis

Full Clinical Professor of Radiology, Riverside Health System, Newport News, VA

Vijay U. Rao, MD, PhD 2005 Duke University Cardiology, St. Francis Medical Group, Indianapolis, IN

Nicole Redmond, MD, PhD 2005 Emory University Assistant Professor of Preventive Medicine, University of Alabama-Birmingham

Stephen F. Shafizadeh, MD, PhD

2005 University of Chicago

Fellowship in Microsurgery, Cerebrovascular and Skull Base Surgery, Arkansas Neuroscience Institute

Justin Turner, MD, PhD 2006 Johns Hopkins Assistant Professor of Otolaryngology-Head & Neck Surgery and Biomedical Engineering (dual appt), Vanderbilt University School of Medicine

John Yordy, MD, PhD 2006 MD Anderson Radiation Oncologist, Anchorage & Valley Radiation Therapy Centers, Anchorage, AK

Zachary Bowman MD, PhD 2007 UCSD Maternal/Fetal Medicine Specialist, MAHEC Ob/Gyn Specialist, Asheville, NC

Lena Heung, MD, PhD 2007 Baystate/Tufts Affiliate

Fellow, Infectious Diseases, Memorial Sloan Kettering Cancer Center

Shantae Jenkins, MD, PhD 2007 MUSC Hospitalist, Colleton Medical Center Eric Sribnick, MD, PhD 2007 Emory University Pediatric Neurosurgeon,

Nationwide Children's Hospital, Columbus, OH

Tarek Taha, MD, PhD 2007 Indiana University

Orthopedic Trauma Surgeon, St. Mary's of Michigan Orthopedic Assoc, Saginaw, MI

*Deceased

David Arrington, MD, PhD 2008 Georgetown University/MUSC

Upper Savannah Radiological Associates, Greenwood, SC

Mary Lee Gregory, MD, PhD

2008 Baystate/Tufts Affiliate

Fellow, Neurodevelopmental Disabilities, Kennedy-Krieger Institute/Johns Hopkins Hospital

Gregor Krings, MD, PhD 2008 Mass. General Hospital/UCSF

Research Fellow, Pathology, University of California-San Francisco

John Shea, MD, PhD 2008 Allegheny General

Resident, Emergency Medicine, Allegheny General Hospital

Laura Spruill, MD, PhD 2008 MUSC Assistant Professor, Pathology & Laboratory Medicine, MUSC

Brice Williams, MD, PhD 2008 University of Utah Adjunct Faculty in Ophthalmology, University of Utah

Saeed ElOjeimy, MD, PhD 2009 University of Washington

Assistant Professor, Radiology, University of New Mexico

Amanda Galloway Hartke, MD, PhD

2009 University of Texas Southwestern-Dallas

Pediatric Hospitalist, Greenville Hospital System, Greenville, SC

Jason Guichard, MD, PhD 2009 University of Alabama-Birmingham

Cardiology Fellow, ABIM Research Pathway in Cardiovascular Diseases, University of Alabama-Birmingham

Mark Hallman, MD, PhD 2009 MUSC/Fox Chase Cancer Center

Resident, Radiation Oncology, Fox Chase Cancer Center

Youssef Zeidan, MD, PhD 2009 Stanford University

Assistant Professor, Radiation Oncology, University of Miami/Sylvester Comprehensive Cancer Center

Rany Abdallah, MD, PhD 2010 MUSC/ Lenox Hill/Rush

Fellow, Pain Management, University of Pittsburgh

Jamie Fraser, MD, PhD 2010 National Institutes of Health

Resident, Combined Pediatrics/Medical Genetics Training Program, Children's National Medical Center, Washington, DC, and National Human Genome Research Institute, National Institutes of Health, Bethesda, MD

Mona Taleb, MD, PhD 2010 Mt. Sinai Medical Center-Miami/ Wayne State

Resident, Surgery, Wayne State University

Juan Varela, MD, PhD 2010 Johns Hopkins University

Assistant Professor, Hematology/Oncology, MUSC

*Deceased

Jonathan Butler, MD, PhD 2011 Vanderbilt Resident, Adult Neurology, Vanderbilt University Medical Center

Justin Ellett, MD, PhD 2011 MUSC Resident, Urology, MUSC

Loretta Jophlin, MD, PhD 2011 Mt. Sinai Fellow, Gastroenterology & Hepatology, MUSC

Jason Lockrow, MD, PhD 2011 University of Washington

Resident, Pediatric Neurology, University of Washington

Phillip Moschella, MD, PhD 2011 University of Cincinnati

Resident, Emergency Medicine, University of Cincinnati

Michael O’Quinn, MD, PhD 2011 MUSC/VCU Resident, Internal Medicine, Virginia Commonwealth University

Brian Snarr, MD, PhD 2011 University of Texas-Southwestern

Pediatric Cardiologist, Children’s Hospital of Philadelphia

Jarrett Walsh, MD, PhD 2011 University of Iowa Resident, Otolaryngology, University of Iowa

Adnan Al-Ayoubi, MD, PhD 2012 MUSC Research Assistant Professor, St. Luke’s-Roosevelt Hospital Center

DeAnna Baker Frost, MD, PhD

2012 Duke Fellow, Rheumatology, MUSC

Christopher Gault, MD, PhD

2012 University of Pennsylvania

Resident, Pathology, University of Pennsylvania

Linda Heffernan-Stroud, MD, PhD

2012 Eastern Virginia Medical Center

Resident, Dermatology, Eastern Virginia Medical Center

Russell Jenkins, MD, PhD 2012 Mass. General Fellow, Medical Oncology, Dana Farber Cancer Institute

Khaled Moussawi, MD, PhD

2012 Mass. General Resident, Neurology, Brigham & Women’s Hospital

Thomas Mullen, MD, PhD 2012 Tufts/University of Washington

Resident, Radiation Oncology, University of Washington

Ryan Rhome, MD, PhD 2012 MUSC/Mt. Sinai Resident, Radiation Oncology, Mount Sinai Hospital

Adrian Sproul, MD, PhD 2012 MUSC/UNC Chapel Hill

Resident, Anesthesiology, UNC-Chapel Hill

Andre Eaddy, MD, PhD 2013 Vanderbilt Resident, Internal Medicine, Vanderbilt University

Joseph Palatinus, MD, PhD 2013 Beth Israel Deaconess

Physician Scientist, Cardiology, Cedars Sinai Medical Center, Los Angeles, CA

Amena Smith, MD, PhD 2013 Johns Hopkins Resident, Pediatrics, Johns Hopkins Hospital

Kyle Strickland, MD, PhD 2013 Brigham and Women’s Hospital

Fellow, Cytopathology, Brigham and Women’s Hospital

Peter Tang, MD, PhD 2013 University of Minnesota

Resident, Ophthalmology, University of Minnesota

*Deceased

Parker Wilson, MD, PhD 2013 Yale Resident, Pathology, Yale New Haven Hospital

Joseph Cheng, MD, PhD 2014 MUSC Resident, Psychiatry, Medical University of South Carolina

Anna-Maria De Costa, MD, PhD

2014 MUSC/University of Wisconsin

Resident, Radiation Oncology, University of Wisconsin

G. Daniel Grass, MD, PhD 2014 Greenville Hospital System/Moffitt Cancer Center

Resident, Radiation Oncology, Moffitt Cancer Center in Tampa

Armina Omole, MD, PhD 2014 University of Pennsylvania

Resident, Neurology, University of Pennsylvania

David Perry, MD, PhD 2014 Greenville Hospital System/MUSC

Resident, Dermatology, MUSC

Sahar Saddoughi, MD, PhD

2014 Mayo School of Medicine

Resident, Cardiothoracic Surgery, Mayo School of Medicine

Lee Wheless, MD, PhD 2014 Vanderbilt Resident, Dermatology, Vanderbilt University

Joseph Alge, MD, PhD 2015 Baylor Resident, Pediatric Physician Scientist Track, Baylor University

S. Obaidullah Aseem, MD, PhD

2015 Mayo School of Medicine

Resident, Medicine with GI Physician Scientist Track, Mayo Clinic

Tiffany Baker, MD, PhD 2015 MUSC Resident, Pathology, MUSC

Thomas Beckham, MD, PhD

2015 Memorial Sloan Kettering

Resident, Radiation Oncology, Memorial Sloan Kettering

Mohammad Dahrouj, MD, PhD

2015 Indiana Univ/Harvard

Transitional Medicine, Indiana University Resident, Ophthalmology, Harvard

Rebecca Knackstedt, MD, PhD

2015 Cleveland Clinic Resident, Plastic Surgery, Cleveland Clinic

Keely Marshall, MD, PhD 2015 Loyola/University of Pittsburgh

Transitional Medicine, Loyola University Resident, Dermatology, University of Pittsburgh

Ahmad Mashmoushi, MD, PhD

2015 University of Texas Southwestern-Dallas

Resident, Pediatrics, University of Texas Southwestern-Dallas

Alton Sutter, MD, PhD 2015 Beth Israel Deaconess

Resident, Surgery, Beth Israel Deaconess Medical Center

Joseph Taylor, MD, PhD 2015 Yale Resident, Psychiatry, Yale University

HIGHLIGHTS (2014-2015) The national prominence of the program continues to increase significantly. This year, we had 177 applications. The quality of the applicant pool remains very high. We interviewed a total of 60 applicants. The average GPA and MCAT scores of the interviewees were 3.75 and 33, respectively. We had a total of 11 new students matriculate. Their GPA and MCAT scores were 3.75 and 32.4, respectively. Of particular note, is the extensive undergraduate research experiences that the applicants had. It was clear during the recruitment process that we continue to compete with the best programs in the country. Shanon Weber, incoming first year student, was awarded the annual MUSC Physicians/MSTP scholarship as well as the Suzann Pershing Award. From the Hollings Cancer Center, Nathaniel Jensen and Hyunwoo Kwon received a Abney scholarship. The nine students who were awarded NIH predoctoral fellowships from the training grant are Sagar Bajpai, Daniel Bonthius, Stewart Cox, Hannah Knochelmann, Christopher Mullins, Winston Plunkett, Joshua Smith, Catherine Svetcharnik and Danh Tran. The website is in the process of being redesigned with input from our students. The visiting professor seminar series has been reactivated. The plan is to have one to two speakers during the upcoming year. Congratulations to Jacob Bowers, Danielle Desjardins and Doug Roberts-Wolfe who received Ruth Kirschstein NSRA fellowships. Our success rate for obtaining these NRSA fellowships is approximately twice the national average, which is 30%. Currently, 13 of our students are the recipients of a competitive intramural or extramural individual fellowship. Our new students and their undergraduate institutions are listed below.

Sagar Bajpai University of Maryland Baltimore County Daniel Bonthius Wartburg College Stewart Cox University of Colorado, Boulder Maya Eid American University of Beirut Hannah Knochelmann University of Notre Dame Allison Meadows University of Virginia Christopher Mullins University of North Carolina Chapel Hill Catherine Svetcharnik University of Colorado Ralph Tanios American University of Beirut Shannon Weber Richmond University Melanie Wiley University of Maryland Baltimore County

This year we graduated ten students.

Institution for Residency Field of Study Joseph Alge Baylor Pediatrics S. Obaidullah Aseem Mayo Clinic Internal Medicine Tiffany Baker MUSC Pathology Thomas Beckham Memorial Sloan Kettering Radiation Oncology Mohammad Dahrouj Harvard University Ophthalmology Rebecca Knackstedt Cleveland Clinic Plastic Surgery Keely Marshall University of Pittsburgh Dermatology Ahmad Mashmoushi University of Texas Southwestern Pediatrics Alton Sutter Beth Israel Deaconess Surgery Joseph Taylor Yale University Psychiatry

Joseph Taylor was named as co-recipient of the Distinguished Graduate of the Year Award. He will return in August to present the Liz Chesterman Memorial lecture to the incoming graduate students. Tiffany Baker was chosen as the 2015 Academic Excellence and Achievement in Pathology Award Gold Recipient from the American Society of Clinical Pathology. Craig Kutz was chosen as a Mission Specialist and Chief Medical Officer for NASA Human Exploration Research Analog. His role was to act as the Chief Medical Officer in simulated deep space mission for NASA. The focus was mainly on behavioral health and performance, crew communication, crew autonomy, and human factors of spaceflight. The information gathered through this mission informed NASA scientists and flight surgeons to better understand the stresses and countermeasures necessary for astronauts to visit places such as Mars or an asteroid. The monthly student seminar series, which are organized by the students, continues to be very successful. It is scheduled for the fourth Monday of each month at 5:00 p.m. Faculty from our institution presented informal research seminars at each of the meetings. These interactions have resulted in several students choosing the presenters as mentors for research projects. This year, six students who were ready to defend their dissertation presented their research. This provided an excellent venue for them to practice their presentation. It also allowed the other students in the program to learn about their colleague’s research.

7/7/14 Tucker Marrison 12/1/14 Tina Zhang 6/1/15 Ryan Whitaker 6/3/15 Joshua Smith 6/4/15 Jennifer Scott 6/8/15 Craig Kutz

Our Translational Medicine Seminar series has been a great success. Each one of our senior students paired with one of our faculty to present a clinical case. This was followed by a research discussion by the faculty member focused on the disease that was presented. The topics and speakers are listed below: 9/8/14 Alton Sutter and Satish Nadig, MD, D.Phil. Towards Operational Tolerance: minimizing systemic side-effects of conventional immunotherapy 9/22/14 Ahmad Mashmoushi and Andrew Goodwin, MD Sepsis, Mending Leaky Vessels 1/12/15 Tiffany Baker and Steven Carroll, MD, PhD Good Things in a Small Package: Cancer Genomics and Therapeutics in Mouse Models of Nervous System Neoplasia 2/16/15 Obaidullah Aseem and Gary Gilkeson, MD Cellular Therapy for Systemic Lupus 3/16/15 Rebecca Knackstedt and Sebastiano Gattoni-Celli, MD & Stephen Savage, MD The Importance of Vitamin D in Prostate Cancer 3/30/15 Joseph Alge and Milos Budisavljevic, MD New Insights into the Pathogenesis of Focal Segmental Glomerulosclerosis 4/20/15 Joseph Taylor and Gregory Sahlem, MD An Interventional Psychiatry Case Study: Using Triple Chronotherapy to Treat Suicidality and Treatment-Resistant Depression The Translational Sciences Clinics have proven to be a very rewarding and successful experience for our students. Both the students and faculty have provided very positive evaluations. During this past year six students; Craig Kutz, Tucker Marrison, Jennifer Scott, Joshua Smith, Ryan Whitaker and Tina Zhang successfully defended their Ph.D. dissertations. This has also been an exciting year for many of our students. David Hartman and Erica Herzig, Abby Washispack and Ryan Southard, and Katelyn Williams and Miguel Valenzula became engaged. Keely and Chris Marshall welcomed baby girl Etta in August, Bryce and Danielle Johnson welcomed baby boy Reid in October and Ken and Katie Noguchi welcomed baby girl Ruby in January.

Abby Washispack & Ryan Southard Ken & Ruby Noguchi

Katelyn Williams & Miguel Valenzula Finn & Reid Johnson Our students continue to garner many honors and awards that you will see listed after their names. Including the incoming class, we currently have 53 students in the program. GOALS FOR 2015-2016

• We will continue to try to identify philanthropic support for the program • Increase the size and quality of our applicant pool • Formally evaluate the program via the instrument developed at the time of the

submission of the grant • Implement the new IDP (Individual Development Plan)

AWARDS AND HONORS (2014-2015) Listed below are the many honors and awards our students have garnered during the past year. Student’s Name (Year of Matriculation) Ali Alawieh (2013) 3rd Place Poster Award. Frontiers in Neuroscience Research Day 2015 American Heart Association MAA Winter 2015 Predoctoral Fellowship 2015 Tiffany Baker (2009) Ruth L. Kirschstein National Research Service Award F30 2009-2015 Paul B. Underwood Chapter of the Gold Humanism Honor Society Secretary for PATHOS (MUSC Pathology Interest Group) 2014 Secretary for MUSC Gold Humanism Honor Society 2014 Finalist, Distinguished Graduate Award 2015 Thomas Beckham (2007) Finalist, Distinguished Graduate Award 2015 Alpha Omega Alpha Honor Society Inductee 2015 South Carolina Electric & Gas Scholarship 2014-2015 We Are Family (501(c)3) Board of Directors President 2014-2015 MUSC SafeZone Advisory Committee 2012-2015 Brandon Bentzley (2009) NIH NIDA NRSA Individual Predoctoral Training Grant (F30) – F30DA035065 2013-2016 Alpha Omega Alpha Honor Society Inductee 2015 Alpha Omega Alpha Honor Society Vice President 2015 Krishna Bharani (2013) NIH/MSTP Predoctoral Fellowship Training Grant, GM008716 2013-2015 Jacob Bowers (2011) 1st Place Graduate Student Oral Division, Perry V. Halushka Student Research Day 2014 NCI Fellowship Grant 1 F30-CA200272-01 2015 Robert Cameron (2011) NIH NRSA F30 DK104550 2014-2018 NIH HL007260 T32 Cardiovascular Training Grant Predoctoral Fellowship 2013-2014 Mohammad Dahrouj Alpha Omega Alpha Honor Society Inductee 2015 Reviewer, PLOS ONE 2014~2015

Mohammed Dany (2013) MUSC Presidential Scholar 2014-2015 ASCI/APSA Best Presentation Award ASCI/AAP/APSA Annual meeting 2015 American Physician Scientist Association Trainee Travel Award ASCI/AAP/APSA Annual meeting 2015 Central Society for Clinical and Translational Research Trainee Travel Award CSCTR 2015 Annual Meeting 2015 MUSC Student Leadership Society Honor Award 2015 MUSC Ray Greenberg Presidential Scholar Award 2015 American Society for Investigative Pathology ASIP award for outstanding research in experimental pathology. Experimental Biology meeting. Boston, MA 2014 Southeastern Medical Scientist Symposium SEMSS Best Poster Presentation Award 2014 Danielle Desjardins (2011) NIH HL007260 T32 Cardiovascular Training Grant Predoctoral Fellowship 2013-2015 MUSC Presidential Scholars Award 2014-2015 George Russell Glenn (2010) MUSC MSTP Representative to APSA 2014-2015 Jennifer Blakely Harmon (2007) NIH NIDDK F30 NRSA Predoctoral Fellowship, Award# 1F30DK091107 2011-2014 David Hartmann (2012) NIH/MSTP Predoctoral Fellowship Training Grant, GM008716 2013-2015 Gold Humanism Honor Society 2014 Travel award for American Physician Scientists Association’s Annual Meeting 2015 Daniel Herr (2011) Southeastern Predoctoral Clinical and Translational Research Award, TL1 Trainee 2013-2015 Nathaniel Jensen (2013) NIH/MSTP Predoctoral Fellowship Training Grant, GM008716 2013-2015 Christopher Bryce Johnson (2009) NIH NCI NRSA Individual Predoctoral Training Grant (F30) – F30CA177208 2013-2016 Peterson award and 1st place oral presentation, Perry V. Halushka Student Research Day 2014

Rebecca Weber Knackstedt (2008) MUSC MSTP's Women Advocacy Group, Co-Founder and Co-President, 2014-2015 Alpha Omega Alpha Honor Society Inductee 2014 Craig Kutz (2010) Southeastern Predoctoral Clinical and Translational Research Award, TL1 Trainee 2013-2015 1st Place Graduate Poster; MUSC Dept. of Medicine Research Symposium 2014 1st Place Oral Presentation; MUSC and USC Depts. of Drug Discovery 2014 2nd Place Poster; Charleston Research Institute Ralph H. Johnson VAMC Research Award 2014 MUSC College of Medicine Outstanding Student Volunteer of the Year 2015 Finalist for the Charles H. Banov, MD, Humanitarian Award 2015 Nomination by Peers for MSUC Student Leadership Society 2015 Anthony Leonard (2008) Student Travel Award to the CYTO 2014 Meeting 2014 Danielle Lowe Graduate Student Association Travel Award 2014 Ken Noguchi (2012) MUSC Hollings Cancer Center Abney Scholarship 2013-2015 Sanket Pattanaik (2013) NIH/MSTP Predoctoral Fellowship Training Grant, GM008716 2013-2015 Winston Plunkett (2014) MUSC Physicians/MSTP Scholar 2014-2015 Pershing Scholarship 2014-2015 Douglas Roberts-Wolfe (2011) Southeastern Predoctoral Clinical and Translational Research Award, TL1 Trainee 2013-2015 NIH NCI NRSA Individual Predoctoral Training Grant (F30) – 1F30DA038893 2015-2018 Jennifer Scott 2nd Place Award for Oral Presentation for PhD students. Perry V Halushka Student Research Day 2014 MUSC Department of Medicine Student Poster Presentation Award 2014

Joseph Taylor (2007) NIDA NRSA F30 Fellowship Award, National Institutes of Health, NIDA 1F30DA033748-01 2012-2015 DREAM Center Neurology Clinic Student Coordinator 2014-2015 Charles H. Banov, MD Humanitarian Award, MUSC 2014 Scholarship to the 27th Annual Update in Psychiatry: Clinical Brain Stimulation, MUSC 2014 PSY860: Interventional Psychiatry Elective Creator 2014 Co-Recipient, College of Graduate Studies Distinguished Graduate Award 2015 Jonathan Turner (2013) NIH/MSTP Predoctoral Fellowship Training Grant, GM008716 2013-2015 Abigail Washispack (2012) NIH/MSTP Predoctoral Fellowship Training Grant, GM008716 2013-2014 NIH HL007260 T32 Cardiovascular Training Grant Predoctoral Fellowship 2014-2015 Ryan Whitaker (2008) Ruth L. Kirschstein National Research Service Award F30 Fellowship, 1F30DA033748-01 2012-2016 Xiaoyi Tina Zhang (2008) Ruth L. Kirschstein NRSA Fellowship Recipient F30CA165518-01 2012-2016 American Medical Association Seed Grant Reviewer 2014-2015 1st place, Poster presentation, Senior category. James B. Edwards College of Dental Medicine Scholars Day, Charleston, SC 2014

PUBLICATIONS Our students have also been very productive in their research endeavors, as witnessed by their publication records. In 2014-2015 they authored or co-authored 59 manuscripts that have been published or are in press and an additional 25 manuscripts have been submitted. One book chapter has been published, and they submitted 82 abstracts for presentation.

Ali Alawieh (2013) Manuscripts: Alawieh, A., Musharrafieh, U., Jaber, A., and Bizri, A. Revisiting leishmaniasis in the time of war: the Syrian conflict and the Lebanese outbreak. International Journal of Infectious Diseases. 2014 Dec;29:115-9. PMID: 25449245. Razafsha M, Khaku A, Azari H, Alawieh A, Behforuzi H, Fadlallah B, Kobeissy FH, Wang KK, Gold MS. Biomarker identification in psychiatric disorders: from neuroscience to clinical practice. Journal of Psychiatric Research. 2015 Jan;21(1):37-48. PMID: 25603450.

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Alawieh A, Mondello S, Kobeissy F, Shibbani K, Bassim M. Proteomics studies in inner ear disorders: pathophysiology and biomarkers. Expert Review Proteomics. 2015 Apr;12(2):185-96. PMID: 25795149. Alawieh A, Nasser Eldine R, Youssef M, and Bizri AR. Challenges in the Treatment of Acute Fulminant Hepatitis B: Case Report and Literature Review. J Med Liban. 2015 ; 63 (2). Alawieh A, Sabra Z, Bizri A, Davies C, White R, Zaraket F. A computational model to monitor and predict trends in bacterial resistance. Journal of Global Antimicrobial Resistance. In Press 2015 Alawieh A, Sabra Z, Sabra M, Tomlinson S, Zaraket F. A Rich-Club Organization in Brain Ischemia Protein interaction Network. Scientific Reports. In Press 2015 Alawieh A, Narang A, Tomlinson S. Complementing Regeneration. Oncotarget. In Press 2015 Alawieh A, Sabra Z, Zaraket F, Hamadeh R, Bizri A. Syrian Conflict and Polio Threat to Lebanon: Current Status and Modeling of Potential Outbreak. Journal of Epidemiology and Infection. (Under Review). 2015 Alawieh A, Sabra M, Sabra Z, Tomlinson S, Zaraket F. Molecular Architecture of Spinal Cord Injury Protein Interaction Network. PLOS One. (Under Review) 2015 Alawieh A, Elvington A, Tomlinson S. Complement in Stroke: Have We Gone Anywhere? Frontiers in Immunology. (Under Review). 2015 Alawieh A, Elvington A, Zhu H, Yu J, Atkinson C, Kindy NS, Tomlinson S. Targeted complement inhibition reduces injury and improves recovery in the subacute phase of murine ischemic stroke. Stroke. (Submitted). 2015 Book Chapters: Alawieh A, Sabra Z, Zhang Z, Kobeissy F, Wang K. Neuroproteomics and Neurosystems Biology in the Quest of TBI Biomarker Discovery. In: Biomarkers of CNS injury and Neurological Disorders, CRC Press. Editors: K. Wang, Z Zhang, and F. Kobeissy. 2014, ISBN 978-1-4822-3982-9 Abstracts: Alawieh A, Sabra M, Sabra Z, Tomlinson S, Zaraket F. A Rich-club Organization of the Brain Ischemic meta-Proteome: Understanding Stroke Pathogenesis and Therapy Using Graph Theory. Perry V. Halushka Student Research Day 2014. Charleston, S.C.

Alawieh A, Elvington A, Zhu H, Yu J, Atkinson C, Kindy MS, Tomlinson S. Targeted complement inhibition reduces cerebral ischemia-reperfusion injury and improves functional outcome in sub-acute phase of murine ischemic stroke. Society for Neuroscience Meeting, Washington, D.C. 2014 Alawieh A, Sabra M, Sabra Z, Tomlinson S, Zaraket F. Novel Bioinformatics Approach Reveals Pathogenic Mechanisms in Cerebral Ischemia - A Step towards Preclinical Stroke Information Management System. International Stroke Conference, Nashville, TN. 2015 Sabra M, Alawieh A, Sabra Z, Tomlinson S, Zaraket F, Hamadeh G. Semi-Automatic Annotator for Medical Natural Language Processing Applications. American University of Beirut Research Day, 2015. Safieddine M, Zaraket F, Kanj R, Alawieh A, Hamadeh G. Recognition of Medical Records Semantics Using Relational Analysis. American University of Beirut Research Day, 2015. Alawieh A, Sabra M, Sabra Z, Zaraket F, Tomlinson S. A Rich Club Organization in Spinal Cord Injury Interactome Provides Insight into Pathophysiological Mechanisms and Potential Therapeutic Interventions. ASCI/AAP Joint Meeting, Chicago, IL, 2015. Alawieh A, Elvington A, Zhu H, Yu J, Atkinson C, Kindy MS, Tomlinson S. Inhibition of the Alternative Complement Pathway Promotes Long-term Recovery after Cerebral Ischemia Reperfusion Injury. South Carolina Center for Recovery from Stroke Annual Meeting, Charleston, SC, 2015. Alawieh A, Elvington A, Zhu H, Yu J, Atkinson C, Kindy MS, Tomlinson S. The Role of Complement Inhibition in Stroke Long-term Recovery and Response to Rehabilitation. Frontiers in Neuroscience Research Day, Charleston, SC, 2015. (3rd Place Poster Award). Obaidullah Aseem (2006) Abstract: Rosenberg RD, Broderick MC, Aseem O, Duckett AA. Exertional rhabdomyolysis in a sickle cell trait athlete. ACP 2014 SC Chapter Scientific meeting. July 2014 Tiffany Baker Manuscript: Baker TG, Roy S, Brandon CS, Kramarenko IK, Francis SP, Taleb M, Marshall KM, Schwendener R, Lee FS, Cunningham LL. Heat shock protein-mediated protection against cisplatin-induced hair cell death. Journal of the Association for Research in Otolaryngology 2015;16:67-80.

Fahmin Basher (2008) Manuscript: Zhang J, Basher F, Wu JD. NKG2D ligands in tumor immunity: two sides of a coin. Front Immunol. 2015; 6: 97. PMCID: PMC4349182 Basher F, Jeng E, Wong J, Wu JD. Cooperative therapeutic anti-tumor effect of IL-15 agonist ALT-803 and co-targeting soluble NKG2D ligand sMIC. Oncotarget (Under review). Sundararaj K, Thiyagarajan T, Molano I, Basher F, Powers TW, Drake RR, Nowling TK. FLI1 levels impact CXCR3 expression and renal infiltration of T cells and renal glycosphingolipid metabolism in the MRL/lpr lupus prone mouse strain. J Immunol (Under review). Abstracts: Basher F, Lu S, Xiao G, Zhang J, Jarzen J, Neitzke D, Rubinstein M, Wu JD. Modulation of NK Anti-Tumor Immunity by NKG2D Ligands. Perry V. Halushka Student Research Day, Charleston, SC, November 2014. Basher F, Lu S, Xiao G, Zhang J, Jarzen J, Neitzke D, Rubinstein M, Wu JD. Modulation of NK Anti-Tumor Immunity by NKG2D Ligands. Hollings Cancer Center Research Retreat, Charleston, SC, November 2014. Brandon Bentzley (2009) Manuscript: Frank E, Benabou M, Bentzley B, Bianchi M, Goldstein T, Konopka G, Maywood E, Pritchett D, Sheaves B, Thomas J. Influencing circadian and sleep-wake regulation for prevention and intervention in mood and anxiety disorders: what makes a good homeostat? Annals of the New York Academy of Sciences, 2014;1334(1), 1–25. PMC4350368 Bentzley BS, Barth KS, Back SE, Book SW. Discontinuation of Buprenorphine Maintenance Therapy: Perspectives and Outcomes. Journal of Substance Abuse Treatment, 2015;52:48–57. PMC4382404 Perkel JK, Bentzley BS, Andrzejewski ME, Martinetti MP. Delay discounting for sucrose in alcohol-preferring and nonpreferring rats using a sipper tube within-sessions task. Alcoholism, Clinical and Experimental Research. 2015;39(2), 232–238. PMC4331455 Bentzley BS, Aston-Jones G. Orexin-1 receptor signaling increases motivation for cocaine-associated cues. European Journal of Neuroscience, 2015;41(9):1149–1156. PMC4420694

Bentzley BS, Barth KS, Back SE, Aronson G, Book SW. Patient perspectives associated with intended duration of buprenorphine maintenance therapy. Journal of Substance Abuse Treatment. 2015 DOI: 10.1016/j.jsat.2015.04.002 NIHMS678860 (No PMC until published in print.) Bentzley BS, Aston-Jones G. Inhibiting subthalamic nucleus decreases cocaine demand and relapse: Therapeutic potential. Addiction Biology. (Under review) 2015 Porter-Stransky KA, Bentzley BS, Aston-Jones G. Individual differences in orexin 1 receptor modulation of motivation for the opioid remifentanil. Addiction Biology. (Under review) 2015 Abstract: Aronson G, Bentzley BS, Book SW. Buprenorphine treatment of opiate use disorder: patient perspectives. Drug Abuse Research Track Summer Research Day, Charleston, SC. 2014 Cox BM, Bentzley BS, See RE, Reichel CM, Aston-Jones G. Motivation to self-administer methamphetamine in a behavioral-economics paradigm predicts the effect of oxytocin on relapse behavior. Abstract for poster presentation, 44rd Annual Society for Neuroscience Meeting, Washington, DC. 2014 Kawa A, Bentzley BS, Robinson TE. Individual differences in motivation for cocaine assessed using a behavioral economics procedure. Abstract for poster presentation, 44rd Annual Society for Neuroscience Meeting, Washington, DC. 2014 Zimmer BA, Bentzley BS, Aston-Jones G. Orexin/hypocretin knockdown decreases cocaine seeking but does not alter cocaine taking. Abstract for poster presentation, 44rd Annual Society for Neuroscience Meeting, Washington, DC. 2014 Freeman LR, Bentzley BS, Aston-Jones G. Sex differences in demand for highly palatable food rewards: Role of orexin neurons. Abstract for poster presentation, 44rd Annual Society for Neuroscience Meeting, Washington, DC. 2014 Bentzley BS, Aston-Jones G. Oxytocin blocks stress-induced reinstatement of cocaine seeking in proportion to the magnitude of baseline reinstatement behavior. Abstract for poster presentation, 53rd Annual Society of Neuropsychopharmacology Meeting, Phoenix, AZ. 2014 Krishna Bharani (2013) Manuscripts: Baranello R, Bharani KL, Padmaraju V, Chopra N, Lahiri D, Greig N, Pappolla M, Sambamurti K. Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer’s disease. Current Alzheimer Research, 2015;12(1), 32-46. PMCID: In progress

Bharani KL, Paller KA, Reber PJ, Weintraub S, & Morrison RG. Electrophysiology of rule-based category learning as a function of age. (Under Review) 2015 Morrison RG, Reber P, Bharani KL, Paller KA. Neural dissociations in category learning: An electrophysiological approach. (Under Review) 2015 Beischel W, Mandel N, Bharani KL, Wells B, Morrison RG. Learning from your mistakes: Neural correlates of effective face-name association learning during retrieval practice. (Under Review) 2015 Jacob Bowers (2011) Manuscripts: Nelson MH, Kundimi S, Bowers JS, Rogers CE, Huff LW, Schwartz KM, Thyagarajan K, Little EC, Mehrotra S, Cole DJ, Rubinstein MP, Paulos CM. The inducible costimulator augments Tc17 cell responses to self and tumor tissue. Journal of Immunology, 2015 Feb 15; 194(4): 1737-47. PMID: 25576595. Bowers JS, Nelson MH, Kundimi S, Bailey SR, Huff LW, Schwartz KM, Cole DJ, Rubinstein MP, Paulos CM. Dendritic Cells in Irradiated Mice Trigger the Functional Plasticity and Antitumor Activity of Adoptively Transferred Tc17 Cells via IL12 Signaling. Clinical Cancer Research, Epub 2015 Apr 22. PMID: 25904754. Abstracts Bowers JS, Kundimi S, Nelson MH, Huff LW, Bailey SR, Rogers CE, Schwartz KM, Cloud CM, Little EC, Mehrotra S, Cole DJ, Rubinstein MP, Paulos CM. Lymphodepletion-induced IL-12 enhances Tc17 cell plasticity and antitumor activity. Poster Session, National MD/PhD Student Conference, Keystone CO July 18-21, 2014 Bowers JS, Nelson, MH, Diven MA, Majchrzak K, Bailey SR, Paulos CM. Th17 cells remarkably retain their capacity to eliminate late-stage melanoma. Oral Presentation, Perry V. Halushka Student Research Day, MUSC Charleston SC, November 14, 2014 Laura Briggs (2008) Manuscripts: Briggs LE, Phelps A, Lockhart M, Wessels A. Wnt/β-catenin signaling acts downstream of the Sonic Hedgehog pathway in regulating the development of the Dorsal Mesenchymal Protrusion. Developmental Dynamics. (Under revision) 2015 Robert Cameron (2011) Manuscript: Leonard AP, Cameron RB, Speiser JL, Wolf BJ, Peterson YK, Schnellmann RG, Beeson CC, Rohrer B. High Content Microscopic Analysis of Mitochondrial Morphology and Membrane Potential Using Morphological Binning. Biochem Biophys Acta 2015 1853(2): 348-60. PMCID: PMC4289477

Abstracts: Cameron RB, Schnellmann RG. Formoterol and tomoxetine induce mitochondrial biogenesis by activating Akt and guanylate cyclase. Drug Discovery and Biomedical Sciences Graduate Retreat, October 2014. Cameron RB, Beeson CC, Schnellmann RG. Formoterol Induces Renal Mitochondrial Biogenesis Through Gbg-Dependent Signaling. ASN Kidney Week. Submitted. 2015 Mohammad Dahrouj (2010) Manuscripts: Alsarraf O, Fan J, Dahrouj M, Chou CJ, Yates PW, Crosson CE. Acetylation preserves retinal ganglion cell structure and function in a chronic model of ocular hypertension. Investigative ophthalmology & visual science 2014, 55:7486-93. Alsarraf O, Fan J, Dahrouj M, Chou CJ, Menick DR, Crosson CE. Acetylation: A lysine modification with neuroprotective effects in ischemic retinal degeneration. Exp Eye Res. 2014 Oct; 127:124-31 Dahrouj M, Vislisel JM, Raecker M, Mal try AC, Goins KM. Posterior Polymorphous Corneal Dystrophy (PPMD). Feb 23, 2015; Available from: http://EyeRounds.org/cases/208-PPMD.htrn Dahrouj M, Desjardins DM, Liu Y, Crosson CE, Ablonczy Z. Receptor mediated disruption of retinal pigment epithelium function in acute glycated-albumin exposure. Exp Eye Res 2015 Jun 10;137:50-56. doi: 10.1016/j.exer.2015.06.004. [Epub ahead of print] Mohammed Dany (2013) Manuscripts: Dany M, Ogretmen B. Ceramide induced mitophagy and tumor suppression. Biochim Biophys Acta. 2015 Jan 26. Review. PubMed PMID: 25634657 PMC25634657 Dany M, Chidiac A, Nassar AH. Human papillomavirus vaccination: assessing knowledge, attitudes, and intentions of college female students in Lebanon, a developing country. Vaccine. 2015 Feb 18;33(8):1001-7. PubMed PMID: 25597945 PMC25597945. Abstracts: Dany M, Ogretmen B. Inhibition of FLT3 in Acute Myeloid Leukemia induces lethal autophagy after activating Ceramide Synthase 1 expression. Southeastern Medical Scientist Symposium. Poster presentation. Emory School of Medicine, Atlanta, GA, August 23, 2014. Dany M, Ogretmen B. Inhibition of FLT3 in Acute Myeloid Leukemia reactivates Ceramide Synthase 1 expression resulting in C18-ceramide mediated mitophagy. Hollings Cancer Center Research Symposium, Charleston, SC, November 7, 2014.

Dany M, Ogretmen B. Inhibition of FLT3 in Acute Myeloid Leukemia reactivates Ceramide Synthase 1 expression resulting in C18-ceramide mediated mitophagy. Perry V. Halushka Student Research Day, Charleston, SC, November 14, 2014. Dany M, Ogretmen B. Regulation of ceramide metabolism by FLT3 signaling in Acute Myeloid Leukemia: defining novel mechanisms of cell death and drug resistance. Lipid Signaling in Cancer/COBRE Seminar, Charleston, SC, December 16, 2014. Dany M, Ogretmen B. Lipid signaling in AML therapy and drug resistance. Grand rounds presentation - Division of Hematology/Oncology. MUSC, Charleston, SC, January 16, 2015. Dany M, Ogretmen B. Ceramide mediated lethal mitophagy in FLT3 targeted therapy for acute myeloid leukemia. Department of Biochemistry-Research and Methods Seminar. MUSC, Charleston, SC, January 13, 2015. Dany M, Ogretmen B. Inhibition of FLT3 in Acute Myeloid Leukemia reactivates Ceramide Synthase 1 expression resulting in C18-ceramide mediated mitophagy. Research Symposium-MUSC College of Medicine, Charleston, SC, February 20, 2015. Dany M, Ogretmen B. Ceramide mediated lethal mitophagy: a novel cell death mechanism in FLT3 targeted therapy for Acute Myeloid Leukemia. Experimental Biology 2015- ASIP- Boston MA, March 30, 2015. Dany M, Ogretmen B. Ceramide mediated lethal mitophagy: a novel cell death mechanism in FLT3 targeted therapy for Acute Myeloid Leukemia. ASCI/AAP/APSA Annual Meeting, Chicago, IL, April 24, 2015. Dany M, Ogretmen B. Ceramide mediated lethal mitophagy: a novel cell death mechanism in FLT3 targeted therapy for Acute Myeloid Leukemia. CSCTR Annual Meeting, Chicago, IL, April 22, 2015. Dany M, Ogretmen B. Ceramide mediated lethal mitophagy: a novel cell death mechanism in FLT3 targeted therapy for Acute Myeloid Leukemia. International Ceramide Conference- Izmir, Turkey, May 8, 2015. Danielle Desjardins (2011) Manuscripts: Nunes-Alves C, Booty M, Carpenter S, Rothchild A, Martin C, Desjardins D, Steblenko K, Kløverpris H, Madansein R, Ramsuran D, Leslie A, Correia-Neves M, Behar S & Lewinsohn D (2015) Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection. PLOS Pathogens 11:e1004849.

Dahrouj M, Desjardins DM, Liu Y, Crosson CE, Ablonczy Z. Receptor mediated disruption of retinal pigment epithelium function in acute glycated-albumin exposure. Exp Eye Res 2015 Jun 10;137:50-56. doi: 10.1016/j.exer.2015.06.004. [Epub ahead of print] George Russell Glenn (2010) Manuscripts: Geyer LL, Glenn GR, De Cecco CN, Van Horn M, Canstein C, Silverman JR, Krazinski AW, Kemper JM, Bucher A, Ebersberger U, Costello P, Bamberg F, Schoepf UJ. CT evaluation of small-diameter coronary artery stents: effect of an integrated circuit detector with iterative reconstruction. Radiology. 2015 (Epub ahead of print) Glenn GR, Helpern JA, Tabesh A, Jensen JH. Quantitative assessment of diffusional kurtosis anisotropy. NMR Biomed. 2015. 28:448-59. Hui ES, Glenn GR, Helpern JA, Jensen JH. Kurtosis analysis of neural diffusion organization. Neuroimage. 2015. 106:391-403. Glenn GR, Tabesh A, Jensen JH. A simple retrospective noise correction scheme for diffusional kurtosis imaging. Magn Reson Imaging. 2015. 33:124-33. Glenn GR, Helpern JA, Tabesh A, Jensen JH. White matter fiber tractography with diffusional kurtosis imaging. NMR Biomed. (Under Review) 2015 Jensen JH, Glenn GR, Helpern JA. Fiber ball imaging. Neuroimage. (Under Review) 2015 Glenn GR, Kuo LW, Chao YP, Lee CY, Helpern JA, Jensen JH. Comparison of Orientation Distribution Functions obtained with Diffusion Spectrum Imaging, Diffusional Kurtosis Imaging, and Diffusion Tensor Imaging. Neuroimage. (In Prep) 2015 Abstracts: Sherrier M, Adisetiyo V, Glenn R, Jensen J, Helpern J. Kurtosis fractional anisotropy: assessment of crossing fibers in the adolescent brain. Perry V. Halushka MUSC Research Day, Charleston, SC. 2014. Glenn R, Jensen J, Chao YP, Lee C, Helpern J, Kuo L. Comparison of Diffusional Kurtosis Imaging (DKI) and Diffusion Spectrum Imaging (DSI) for White Matter Fiber Tractography. International Society for Magnetic Resonance in Medicine, Toronto, CA. 2015. Glenn R, Helpern J, Tabesh A, Jensen J. Quantitative Assessment of Diffusional Kurtosis Anisotropy. International Society for Magnetic Resonance in Medicine, Toronto, CA. 2015.

Glenn R, Helpern J, Tabesh A, Jensen J. Optimization of White Matter Fiber Tractography with Diffusional Kurtosis Imaging. International Society for Magnetic Resonance in Medicine, Toronto, CA. 2015. Hui E, Glenn R, Helpern J, Jensen J. Modeling of Brain Microstructure by Kurtosis Analysis of Neural Diffusion Organization (KANDO). International Society for Magnetic Resonance in Medicine, Toronto, CA. 2015. McKinnon ET, Glenn GR, Benitez A, Jensen JH, Falangola MF, Chan CH, Helpern JA. Quantifying the Number of Crossing Fibers in the Aging Brain Using DKI Tractography. Alzheimer’s Association International Conference, Washington DC. 2015. Helpern J, Glenn R, Kuo L, Lee C, Chao Y, Jensen J. A Comparative Study of White Matter Fiber Tractography Using DTI, DKI, and DSI. American Society for Neuro Radiology, Chicago, IL. 2015. David Hartmann (2012) Abstract: Hartmann DA, Grant RI, Bhat NR, Shih AY. Vascular Amyloid Plaque Burden is Positively Correlated with Leukocyte Rolling in a Mouse Model of Alzheimer’s Disease. Perry V. Halushka Student Research Day, Charleston, SC. November 2014 Daniel Herr (2011) Manuscript: Aune SE, Herr DJ, Kutz CJ, Menick DR. Histone deacetylases exert class-specific roles in conditioning the brain and heart against acute ischemic injury. Front Neurol. 2015; 6: 145. Abstracts: Herr DJ, Aune SE, Menick DR. Inhibition of Class I Histone Deacetylases At Reperfusion Attenuates Cardiac Ischemia reperfusion Injury. Perry V. Halushka Student Research Day, Charleston, SC. November 2014 Aune SE, Herr DJ, Menick DR. Class I HDAC Inhibition Causes Selective Activation of Pro-survival Kinases at Reperfusion in Post-ischemic Hearts. Perry V. Halushka Student Research Day, Charleston, SC. November 2014 Harris LG, Herr DJ, Kasiganesan H, Menick DR. Histone Deacetylase Inhibition Improves Cardiac Function and Prevents Adverse Tissue Remodeling Post Myocardial Infarction By Differentially Regulating the Expression of the CCN Matricellular Genes. Perry V. Halushka Student Research Day, Charleston, SC. November 2014

Nathaniel Jensen (2013) Abstracts: Jensen NR, Duckworth C, Cheung HW. Identifying Novel Targets in CCNE1-amplified Ovarian Cancer. MUSC Department of Pathology Research Day, Charleston, SC, August 2014. Christopher Bryce Johnson (2009) Manuscripts: Rubinstein MP, Su EW, Suriano S, Cloud CA, Andrijauskaite K, Kesarwani P, Schwartz KM, Williams KM, Johnson CB, Li M, Scurti GM, Salem ML, Paulos CM, Garrett-Mayer E, Mehrotra S, Cole DJ. Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8+ T cells. Can Immunol Immunother. 64(5):539-49, 2015. Johnson CB, Riesenberg BP, May BR, Gilreath SC, Li G, Staveley-O’Carroll KF, Garrett-Mayer E, Mehrotra S, Cole DJ, Rubinstein MP. Effector CD8+ T cell engraftment in lymphodepleted hosts is IL-7Rα dependent. Cancer Immunology Research. In Press 2015 Su EW, Moore CJ, Suriano SJ, Johnson CB, Songalia N, Patterson A, Neitzke DJ, Garrett-Mayer E, Mehrotra S, Paulos CM, Doedens AL, Goldrath AW, Li, Z, Rubinstein MP, Cole DJ. IL-2Rα-dependent IL-2 recycling and cell-surface reservoirs enhance immunotherapy. Sci Transl Med. In Press 2015 Johnson CB, Jenkins DD, Perkel JK, Lambert D, Lee KC, Hope K, Rollins LG, Morgan PS, Brown T, Ramakrishnan V, Mulvihill DM, Katikaneni LD. Proton MR spectroscopy and outcome in term neonates with chorioamnionitis. Accepted 2015 Johnson CB, May BR, Cloud CA, Rubinstein MP, Cole DJ. Adoptive transfer of IL-7 responsive CD8+ T cells reduces the lymphodepletion intensity required for optimal tumor control. In preparation 2015 Abstract: Johnson CB, May BR, Rubinstein MP, Cole DJ. Adoptive transfer of IL-7 responsive CD8+ T cells reduces the lymphodepletion intensity required for optimal tumor control. Oral presentation, Perry V. Halushka Student Research Day, Charleston, SC, November 2014. Johnson CB, Riesenberg BP, Neitze DJ, Jeng EK, Marcus WD, Cole DJ, Wong HC, Rubinstein MP. Combinatorial therapy with an IL-15 superagonist (ALT-803) and anti-PD-L1 mAb augment T cell mediated anti-tumor immunity in mice. Society for Immunotherapy of Cancer, National Harbor, MD, November 2014.

Rebecca Weber Knackstedt (2008) Manuscript: Merry C, Perkins M, Mu L, Peterson B, Knackstedt R, Weingart C. Characterization of a novel two component system in Burkholderia cenocepacia. Current Microbiology 69 (2014). Suarez E, Knackstedt R, Jenrette J. Significant fibrosis after radiation therapy in a patient with Marfan syndrome. Radiation Oncology 32 (2014) pp. 1-5. PMCID: PMC4194304. Knackstedt R, Moseley V, Sun S, Wargovich M. The Importance of the Retinoid X Receptor Alpha in Modulating Inflammatory Signaling in Acute Murine Colitis. Digestive Diseases and Sciences 59 (2014) pp 753-759. PMCID: PMC4009739. Knackstedt R, Dixon J, O'Neill P, Herrera F. Rash with Prineo use in bilateral reduction marnmoplasty: a case series. Case Reports in Medicine 2015 (2015) pp 4 pages.PMC4397495. Brown J, Lydecker J, Turner T, Knackstedt R, O'Neil P. A novel approach to training healthcare students in the delivery of evidence-based obesity treatment. Family Medicine. 47 (2015) pp 378-82 McCord C, Gonzalez G, Knackstedt R, Delany K. Fungal infection of the hand clinically mimicking a giant cell tumor in a transplant patient. SCMA Journal. In Press 2015 Gonzalez G, Knackstedt R, Herrera F. Nerve injuries after elective procedures. SCMA Journal. Submitted 2015 Invited Lectures: Knackstedt R. Career Planning Advice. Denison University Guest Lecture. Granville, OH, Oct 2014. Abstracts: Brown J, Lydecker J, Turner T, Knackstedt R, O'Neil P. A novel approach to training healthcare students in the delivery of evidence-based obesity treatment. The Obesity Society Annual Meeting. Boston, MA. November 2014. Craig Kutz (2010) Manuscripts: Kutz CJ, Hoshouser SL, Marrow E, Woster, P. 3,5-Diamino-12,4-triazoles as a novel scaffold for potent reversible LSD1 (KDM1A) inhibitors. Med Chem Commun. 2014, 5, 1863-1870. PMID 25580204. Aune SE, Herr DJ, Kutz CJ, Menick DR. Histone deacetylases exert class-specific roles in conditioning the brain and heart against acute ischemic injury. Front Neurol. 2015; 6: 145. PMCID: PMC4485035. PMID: 26175715

Nowotarski SL, Pachaiyappan B, Holshouser SL, Kutz CJ, Li Y, Sharma SK, Casero RA, Woster PM. Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon chain architectures. Bioorg Med Chem. 2015 Apr 1;23(7):1601-12. PMID 25725609. Abstracts: Kutz CJ, Menick DR, Woster PM. Novel 3,5-diamino-1,2,4-triazole amines as drug candidates to mitigate cardiac ischemia-reperfusion injury. MUSC and University of South Carolina Departments of Drug Discovery Research Retreat, Columbia, SC. 2014 Kutz CJ, Aune SE, Wang H, Woster PM, Menick DR. Improving myocardial function in isolated rat hearts following transient ischemia-reperfusion: utilizing novel chemical probes as a means to divulge a mechanism. MUSC Department of Medicine Research Symposium, Charleston, SC. February 2014 Kutz CJ, Menkin L, OBryan E. Is the WHO Global Burden of Disease relevant in rural East Africa? Unite for Sight Global Health & Innovation Conference, Yale University, New Haven, CT. March 2015 Kutz CJ, Aune SE, Woster PM, Menick DR. Novel amine oxidase inhibitor reveals new therapeutic strategies to reduce myocardial ischemia-reperfusion damage in isolated rat hearts. Association for Clinical and Translational Sciences Annual National Meeting, Washington, DC. April 2014 Kutz CJ, Holshouser SL, Marrow E, Woster PM. 3,5-Diaminotriazoles reveal a novel class of LSD1/KDM1A inhibitors. 34th Annual National Medicinal Chemistry Symposium, Charleston, SC. May 2014 Kutz CJ, Renaud L, Wang H, Holshouser SL, Woster PM, Menick D. Novel 1,2,4-triazole scaffolds as drug candidates to prevent cardiac ischemia-reperfusion injury. Perry V. Halushka MUSC Student Research Day. Charleston, SC. November 2014 Rycenga HB, Kutz CJ, Holshouser SL, Woster PM. 3,5-Diamo-1,2,4-triazole Scaffold for LSD1 Inhibition Reveals New Small Molecule Targets for Spermine Oxidase Inhibitors. Perry V. Halushka MUSC Student Research Day. Charleston, SC. November 2014 Hyunwoo Tony Kwon (2014) Fattouh R, Kwon H (co-first author), Czuczman MA, Copeland JW, Pelletier L, Quinlan ME, Muise AM, Higgins DE, Brumell JH. The Diaphanous-related Formins Promote Protrusion Formation and Cell-to-Cell Spread of Listeria monocytogenes. J Infect Dis. 2015; 211(7):1185-95. PMID: 25281757.

Anthony Leonard (2007) Manuscript: Leonard AP, Cameron RB, Speiser JL, Wolf BJ, Peterson YK, Schnellmann RG, Beeson CC, Rohrer B. High Content Microscopic Analysis of Mitochondrial Morphology and Membrane Potential Using Machine Learning and Morphological Binning, BBA Mol. Cell Res. 2015; 1853(2):348-60 PMID: 25447550, PMCID: PMC4289477 Danielle Clark Lowe (2009) Manuscript: Jenkins D, Martin R, Wiest D, Mulvihill D, Hlavacek A, Turner R, Rollins L, Bentzley J, Hope K, Barbor A, Lowe D, Cox T, Garner S, Chang G. Fetal and Neonatal Effects of N-Acetylcysteine When Used for Neuroprotection in Maternal Chorioamnionitis. J Peds, In Revision 2015 Hughes FM, Kennis JG, Youssef MN, Lowe DW, Shaner BE, Purves JT. The NLRP3 Inflammasome Mediates Inflammation and Voiding Dysfunction in a Lipopolysaccharide-Induced Rat Model of Cystitis. PLOS ONE. Submitted 2015 Nie X, Lowe D, Rollins L, Bentzley J, Fraser J, Martin R, Singh I, Jenkins D. Sex-specific effects of N-Acetylcysteine in neonatal rats treated with hypothermia after severe hypoxia-ischemia. Neuroscience Research. Submitted 2015 Abstract: Lowe DW, Rollins L, Fraser J, Nie X, Bentzley J, Hollis B, Singh I, Jenkins D. Circulating Immune Modulators Correlate with Vitamin D Concentrations after HI Injury in the Neonatal Rat. Neuroscience 2014, Washington, DC, November 2014. Lowe DW, Wiest D, Hollis B, Wagner C, and Jenkins D. 25-OH Vitamin D Over 72 Hours in Neonatal Hypoxic Ischemic Encephalopathy. Darby Research Day 2015, Charleston SC, March 2015. Lowe DW, Nie X, Bentzley J, Hollis B, Singh I, Jenkins D. Vitamin D Metabolism Altered After HI in the Neonatal Rat. Darby Research Day 2015, Charleston SC, March 2015. Lowe DW, Wiest D, Hollis B, Wagner C, and Jenkins D. 25-OH Vitamin D Over 72 Hours in Neonatal Hypoxic Ischemic Encephalopathy. Pediatrics Academic Societies 2015, San Diego, CA, April 2015. Lowe DW, Nie X, Bentzley J, Hollis B, Singh I, Jenkins D. Vitamin D Metabolism Altered After HI in the Neonatal Rat. Pediatrics Academic Societies 2015, San Diego, CA, April 2015.

Jamie Mills (2011) Manuscripts: Irish J, Mills J, Ivey B, Wilson R, Guest S, Domkowski A, Kappler C, Hardiman G, Ethier SP. The WHSC1L1 oncogene influences expression and estrogen-independent activation of the estrogen receptor-a in SUM-44 breast cancer cells, and is associated with ERa over expression in luminal B human breast cancers. Cancer Research. Under Review 2015 Daniel Neitzke (2010) Manuscript: Su EW, Moore CJ, Suriano SJ, Johnson CB, Songalia N, Patterson A, Neitzke DJ, Garrett-Mayer E, Mehrotra S, Paulos CM, Doedens AL, Goldrath AW, Li, Z, Rubinstein MP, Cole DJ. IL-2Rα-dependent IL-2 recycling and cell-surface reservoirs enhance immunotherapy. Submitted 2015 Abstract: Neitzke D, Paulos C, Cole D, Rubinstein M. Th17 cell engraftment is improved by lymphodepletion but does not depend on IL7. Cancer Immunology and Immunotherapy: Delivering the Promise, Bethesda, MD, October 9-10, 2014 Johnson CB, Riesenberg B, Neitzke D, Jeng EK, Marcus WD, Cole DJ, Wong HC, Rubinstein MP. Combinatorial therapy with an IL-15 superagonist (ALT-803) and anti-PD-L1 mAb augment T cell mediated anti-tumor immunity in mice. Society for Immunotherapy of Cancer Annual Meeting, National Harbor, MD, November 6-9, 2014 Neitzke DJ, Paulos C, Cole D, Rubinstein M. Th17 Cell Engraftment is Improved By Host Lymphodepletion But Does Not Depend on IL7. Perry V. Halushka Student Research Day, Charleston, SC. November 2014 Basher F, Lu S, Xiao G, Zhang J, Jarzen J, Neitzke D, Rubinstein M, Wu J. Modulation of NK Anti-Tumor Immunity By NKG2D Ligands. Perry V. Halushka Student Research Day, November 2014 Sanket Pattanaik (2013) Manuscript: Liu J, Pattanaik S, Yao J, Dwyer AH, Pickhardt PJ, Choi, JR, Summers RM. Associations among pericolonic fat, visceral fat and colorectal polyps on CT colonography. Obesity 2014; 23(2):408-414. PMCID: PMC4310815. Saleh Rachidi (2010) Manuscript: Rachidi S, Sun S, Li Z. Endoplasmic reticulum heat shock protein gp96/grp94 is a pro-oncogenic chaperone not a tumor suppressor. Hepatology. 2014 Aug 28. doi: 10.1002/hep.27400. PMID: 25163410

Rachidi S, Wallace K, Day TA, Alberg AJ, Li Z. Lower circulating platelet count and antiplatelet therapy independently predict better outcomes in patients with head and neck squamous cell carcinoma. J Hematol Oncol. 2014 Sep 27;7:65. doi: 10.1186/s13045-014-0065-5. PMID: 25260646 Rachidi S, Sun S, Wu BX, Jones E, Drake RR, Ogretmen B, Cowart LA, Clarke CJ, Hannun YA, Chiosis G, Liu B, Li Z. Endoplasmic reticulum heat shock protein gp96 maintains liver homeostasis and promotes hepatocellular carcinogenesis. J Hepatol. 2014 Nov 22. pii: S0168-8278(14)00854-X. doi: 10.1016/j.jhep.2014.11.010. PMID: 25463537 Zhang Y, Wu BX, Metelli A, Thaxton JE, Hong F, Rachidi S, Ansa-Addo E, Sun S, Vasu C, Yang Y, Liu B, Li Z. GP96 is a GARP chaperone and controls regulatory T cell functions. J Clin Invest. 2015 Feb;125(2):859-69. doi: 10.1172/JCI79014. Epub 2015 Jan 20. PMID: 25607841 Rachidi S, Sood AJ, Patel KG, Nguyen SA, Hamilton H, Neville BW, Day TA. Melanotic neuroectodermal tumor of infancy: A systematic review. J Oral Maxillofac Surg. 2015 Apr 7. doi: 10.1016/j.joms.2015.03.061. PMID: 25936939 Rachidi S, Wallace K, Wrangle JM, Day TA, Alberg AJ, Li Z. Neutrophil-to-lymphocyte ratio and overall survival in all sites of head and neck squamous cell carcinoma. Head Neck. 2015 Jun 3. doi: 10.1002/hed.24159. PMID: 26040762 Rachidi S, Sood AJ, Rumbolt T, Day TA. Intramuscular myxoma of the head and neck: A systematic review of 29 reports and a new case in the paraspinal muscles. Oncol Lett. In Press 2015 Abstract: Rachidi S, Wu B, Nelson M, Riesenberg B, Paulos C, Rubinstein M, Liu B, Li Z. Platelets Subvert Cancer Immune-surveillance. Perry V. Halushka Student Research Day, Charleston, SC, November 2014 Douglas Roberts-Wolfe (2011) Manuscripts: Roberts-Wolfe DJ, Kalivas PW. Glutamate transporter GLT-1 as a therapeutic target for substance use disorders. CNS & Neurological Disorders: Drug Targets. In Press 2015 Garcia-Keller C, Cancela L, Esparza M, Bollati F, Kupchik Y, Roberts-Wolfe D, Gipson C, Brown R, Kalivas PW. Glutamatergic Mechanisms of Comorbidity Between Stress Disorders and Cocaine Addiction. Mol Psychiatry, Under Revision 2015

Abstracts: Roberts-Wolfe DJ, Gipson CD, Scofield MD, Kalivas PW. Transient synaptic potentiation in nucleus accumbens shell and core during extinction and reinstatement of cocaine seeking. Oral session presented at: Translational Science Meeting (ACTS); 2014 April 10; Washington DC. Poster session presented at: National MD/PhD Student Conference; Keystone, CO. July 18, 2014 Roberts-Wolfe DJ, Gipson CD, Scofield MD, Kalivas PW. Extinction Context Evokes Rapid Synaptic Potentiation Following Extinction From Cocaine. Perry V. Halushka Student Research Day, Charleston, SC, November 2014 Sarah Brice Russo (2010) Abstracts: Washispack AN, Russo SB, Cowart LA. The roles of Atg7 and p53 in sphingolipid-dependent autophagy. 49th Annual Southeastern Regional Lipid Conference; 2014 Nov 5-7; Cashiers, North Carolina. Oral presentation. Washispack AN, Russo SB, Cowart LA. Molecular mechanisms of Atg7 and p53 in regulation of sphingolipid-dependent autophagy. Joint 8th Annual International Ceramide Conference and 11th Annual Sphingolipid Club Meeting; 2015 May 6-10; Izmir, Turkey. Poster Presentation. Jennifer Scott (2009) Manuscript: Scott JL, Cunningham, MA, Naga OS, Wirth, JR, Eudaly, JG, Gilkeson, GS Estrogen receptor alpha deficiency modulates TLR mediated PDC-TREM expression in plasmacytoid dendritic cells in lupus prone mice. Under Review 2015 Abstracts: Scott J, Cunningham M, Naga O, Eudaly J, Wirth J, Gilkeson G. Absence of Hormone Responsive Estrogen Receptor Alpha Reduces the Activation of Plasmacytoid Dendritic Cells in Lupus Prone Mice. American College of Rheumatology, November 2014 Scott JL, Cunningham M, Naga O, Wirth J, Gilkeson G. Absence of Hormone Responsive Estrogen Receptor Alpha Reduces the Activation of Plasmacytoid Dendritic Cells in Lupus Prone Mice. Perry V. Halushka Student Research Day, Charleston, SC, November 2014 Scott J, Cunningham M, Naga O, Eudaly J, Wirth J, Gilkeson G. Estrogen Receptor Alpha Impacts Activation of Plasmacytoid Dendritic Cells in Pre-Disease Lupus Prone Mice. Keystone: Dendritic Cells and Macrophages Reunited meeting, March 2015

Joshua Smith (2008) Manuscripts: Smith JA, Stallons LJ, Collier JB, Chavin KD, Schnellmann RG. Suppression of mitochondrial biogenesis through toll-like receptor 4-dependent mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling in endotoxin-induced acute kidney injury. J Pharmacol Exp Ther. 2015; 352(2):346-57. PMCID: PMC4293437. Abstracts: Smith JA, Stallons LJ, Collier JB, Schnellmann RG. TLR4-Dependent MEK/ERK Activation Suppresses Mitochondrial Biogenesis (MB) in a Mouse Model of Sepsis-Induced Acute Kidney Injury (AKI). American Society of Nephrology Kidney Week, Philadelphia, PA, November 2014. Collier JB, Smith JA, Whitaker RM, Schnellmann RG. ERK1/2 Suppresses PGC-1α and Mitochondrial Biogenesis in Endotoxin and I/R-Induced AKI. Society of Toxicology Annual Meeting, San Diego, CA, March 2015. Smith JA, Stallons LJ, Collier JB, Schnellmann RG. Suppression Of Mitochondrial Biogenesis (MB) Through TLR4/MEK/ERK Signaling in a Mouse Model of Sepsis-induced Acute Kidney Injury. Drug Discovery and Biomedical Sciences Annual Graduate Student Retreat, Columbia, SC, October 2014. Erik Strungs (2009) Abstracts: Strungs EG, Lee MH, Luttrell LM. Beta-arrestin2 Intramolecular BRET Conformational Biosensors Correlate with GPCR-arrestin Complex Avidity. Perry V. Halushka Student Research Day. November 2014 Strungs EG, Lee MH, Luttrell LM. Beta-arrestin2 Intramolecular BRET Conformational Biosensors Correlate with GPCR-arrestin Complex Avidity. MUSC Department of Medicine Research Day, Charleston, SC, February 2015. Joseph Taylor (2007) Manuscript: Li X, Fryml L, Rodriguez JJ, Taylor JJ, Borckardt JJ, Short EB, Sahlem G, Roberts D, George MS. Safe management of a bipolar patient with prefrontal repetitive transcranial magnetic stimulation (rTMS) over 7 years and > 2 million stimuli. Brain Stimulation, doi: 10.1016/j.brs.2014.09.005. PMID is 25440291. PMCID in progress Williams NR, Taylor JJ, Lamb K, Hanlon CA, Short EB, George MS. Role of functional imaging in the development and refinement of invasive neuromodulation for psychiatric disorders. World Journal of Radiology, 2014 October 28; 6(10): 756-778. PMID 25349661,PMCID4209423.

Taylor JJ, Larrew T, Omole A, Roberts M, Kornegay A, Kornegay K, Yamada L, Revuelta GJ, Sohn, Hughes T, Edwards J. The feasibility of establishing a free clinic for uninsured patients with neurological disorders. Neurology Clinical Practice. In Press. 2015 Taylor JJ. Those Who Stay. Medical Teacher, In Press. 2015 Abstracts: Badran BW, Taylor JJ, Li X, Hanlon C, George MS. One Step Closer To Patient-Specific Brain Treatments: Interleaved Transcranial Magnetic Stimulation (TMS)/fMRI to Assess the FMRI BOLD Response Before and After High Frequency Repetitive TMS Treatment. Perry V. Halushka Student Research Day, Charleston, SC, November 2014 Badran BW, Taylor JJ, Devries W, McTeague LM, Li X, Hanlon C, George MS. Using interleaved transcranial magnetic stimulation (TMS)/fMRI to assess the BOLD response before and after a single 20 minute session of 10Hz rTMS. Society of Biological Psychiatry, May 2015 Danh Tran (2014) Manuscript: Yoo EM, Trinh KR, Tran D, Vasuthasawat A, Zhang J, Hoang B, Lichtenstein A, Morrison SL. Anti-CD138 Targeted Interferon Is A Potent Therapeutic against Multiple Myeloma. Journal of Interferon & Cytokine Research. 2015 Apr; 35(4):281-91. PMCID: PMC4390003 [Available on 2016-04-01] Abigail Washispack (2012) Abstracts: Washispack AN, Russo SB, Cowart LA. The roles of Atg7 and p53 in sphingolipid-dependent autophagy. 49th Annual Southeastern Regional Lipid Conference; 2014 Nov 5-7; Cashiers, North Carolina. Washispack AN, Russo SB, Cowart LA. Molecular mechanisms of Atg7 and p53 in regulation of sphingolipid-dependent autophagy. Joint 8th Annual International Ceramide Conference and 11th Annual Sphingolipid Club Meeting; 2015 May 6-10; Izmir, Turkey. Poster Presentation. Ryan Whitaker (2008) Manuscript: Whitaker RM, Korrapati MC, Stallons LJ, Jesinkey SR, Arthur JM, Beeson CC, Zhong Z and Schnellmann RG. Urinary ATP Synthase Subunit β is a Novel Biomarker of Renal Mitochondrial Dysfunction in Acute Kidney Injury. Toxicol Sci 2015; 145(1):108-17. Whitaker RM, Corum DC and Schnellmann RG. Mitochondrial Biogenesis as a Pharmacological Target: A New Approach to Acute and Chronic Diseases. Ann Rev Pharm Tox. In Press 2015

Whitaker RM, Stallons LJ, Kneff JE, Alge JL, Harmon JL, Rahn JJ, Arthur JM, Beeson CC, Chan SL and Schnellmann RG. Urinary mitochondrial DNA is a biomarker of renal dysfunction and mitochondrial disruption in acute kidney injury. Kidney International Under Review 2015. Abstracts: Korrapati MC, Whitaker RM, Stallons LJ, Arthur JM and Schnellmann RG. ATP Synthase Subunit Beta is a Novel Urinary Biomarker of Renal Mitochondrial Dysfunction. Society of Toxicology 53rd Annual Meeting and ToxExpo, Phoenix, AZ. March 2014 Garrett SM, Whitaker RM and Schnellmann RG. Accelerated Recovery from Acute Kidney Injury through 5-Hydroxytrypatmine 1F Receptor Agonism. American Society of Nephrology Kidney Week 2014, Philadelphia, PA. November 2014 Korrapati MC, Whitaker RM, Stallons LJ, Arthur JM and Schnellmann RG. Urinary ATP Synthase Subunit Beta is a Novel Biomarker of Mitochondrial Dysfunction in Acute Kidney Injury. American Society of Nephrology Kidney Week 2014, Philadelphia, PA. November 2014 Whitaker RM and Schnellmann RG. Activation of Inflammatory Mediators following Renal Ischemia-Reperfusion Injury Leads to Rapid Suppression of Mitochondrial Biogenic Signaling. American Society of Nephrology Kidney Week 2014, Philadelphia, PA. November 2014 Xiaoyi Zhang (2008) Manuscript: Zhang X, Hyer JM, Yu H, D’Silva NJ, Kirkwood KL. DUSP1 phosphatase regulates the proinflammatory milieu in head and neck squamous cell carcinoma. Cancer Research. 2014; 74(24):7191-7. PMCID: PMC4268021.