Biology 320113.2 Endocrine glands

(pituitary)

p. 427-431

Pituitary is connected to Hypothalamus

Pituitary has 2 lobes

Control of the Anterior is

different from the posterior

Posterior pituitary stores hormones for release

Where the pituitary fits in the big picture!!

Real pituitary

Portal system or vessels

Master Gland

OxytocinAntidiuretic

ACTHTSHHGH

LH/FSHProlactin

Gigantism

12 year old boy 6’ 5”

Too much HGH in youth

usually caused by tumour

Acromegalyenlarged hands, feet & face

Too much HGH as adultUsually caused by tumour

treat tumor or hGH blocking drugs

Pituitary dwarfismtoo little HGH as child

tumor or missing pituitarynote normal proportions

Genetic dwarfism

note out of proportionbig head regular body,

short legs & arms

Prolactin stimulates lactogenesisNormally dopamine inhibits prolactinsuckling stimultes nerves on nipple

hypothalmus stimultes the production of prolactin

Neuroendocrine reflex

Anti-diuretic hormoneproduced in Posterior Pituitary

causes body to retain water

too much salt detected by HYPOADH produced

too little salt detected less ADH produced

Diabetes insipidus=insufficient Anti-diuretic

produced

Oxytocin1 function

Oxytocin2nd function

Oxytocin; Affiliation hormone

Web sites• http://www.umm.edu/endocrin/pitgland.htm• http://arbl.cvmbs.colostate.edu/hbooks/pathphys/endocrine/hypopit/• http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/P/Pituitary.html• http://www.pituitary.org.uk/disorders/