TRACK your polycythemia vera (PV) over time—this provides

an ongoing record of your disease status and can help you spot trends within your health.

TALK to your Healthcare Professional about any health trends you may have noticed while tracking your PV—this helps you play a more active

role in your ongoing care.

Watch for TRENDS within your health when you are tracking your condition—this can help

identify issues that may warrant discussion with your

Healthcare Professional.

The MPN10 is a tool to help assess and track the 10 most clinically relevant MPN symptoms* and their severity over time.

TRENDS to watch for: changes in individual PV symptoms, several symptoms, or an increase in your overall MPN10 score over time

TRACKING your blood counts over time may highlight noteworthy trends for discussion with your Healthcare Professional.

Polycythemia vera (PV) is a rare, chronic blood cancer where the bone marrow produces too many red blood cells. You may also have too many white blood cells and platelets (blood clotting cells) in your blood. PV is part of a group of diseases

called myeloproliferative neoplasms, or MPNs.

MPN10 Symptoms:

*You may experience additional symptoms that a�ect your daily life.

Please contact your Healthcare Professional if any of your symptoms are severe.

TRACKING your PV symptoms can help you monitor your condition over time.

TRACKING changes in the frequency of certain medical procedures may reveal a need to review your current PV management plan.

TALK with your Healthcare Professional regularly about how your PV symptoms are a�ecting you and how they may be changing over time. Sharing all of your results helps ensure that nothing important gets overlooked. Learn more about tracking your symptoms at PVSymptomTracker.com.

High white blood cell count (also called leukocytosis) may increase the risk of blood clots in patients with PV

White Blood Cells

Also called leukocytes, these

cells help fight infection

High hematocrit may be associated

with an increased risk of blood clots, which

can lead to heart attack, stroke, or other clotting complications

Hematocrit

Volume of red blood cells in the blood, stated as

a percentage

In rare cases, extremely high

platelet counts may lead to increased risk of bleeding

Platelets

Cells that help with blood

clotting

Phlebotomy

A procedure in which your hematocrit is

lowered by removing blood from your body.

This process is similar to that of donating blood.

TRENDS to watch for:

Why does this matter?

TRENDS to watch for: a consistent change in your hematocrit, white blood cell count, and/or platelet count

Changes in frequency or less e�ective in maintaining

hematocrit control

Because PV is a progressive condition, it may worsen over time. Tracking your PV can help you identify any trends in your disease and help ensure that you’re having the right conversations with your Healthcare Professional. Remember, when you spot a trend, it’s important to share this information with your Healthcare Professional and discuss any impact it may have on your current management plan.

Voices of MPN and the Voices of MPN logo are registered trademarks of Incyte.© 2018, Incyte Corporation. All rights reserved. MAT-HEM-00117 07/18

Fatigue (tiredness)

Inactivity

Problems concentrating

Itching (especially after a warm shower)

Early feeling of fullness with eating

Abdominal pain or discomfort

Unintentional weight loss (in the last 6 months)

Bone pain (widespread, not joint pain or arthritis)

Fever (>100°F) 0 (absent) 10 (daily) Night sweats

Take an active role in your ongoing PV care. TRACK your condition, watch for meaningful TRENDS, and TALK to your Healthcare Professional about the changes you may have noticed. Use the PV tracking tool available at PVSymptomTracker.com.

TALK with your Healthcare Professional about setting individualized blood count targets and goals for you and be sure to discuss any trends in your counts over time. Learn more about tracking your blood counts at PVSymptomTracker.com.

Three Important Ways to Take an Active Role in Your Care

TRACK, TREND, TALK:

Symptoms

Blood Counts

Procedures

TALK with Your Healthcare Professional