The Obesity Cure

Roadmap to Metabolic Health and

Sustained Weight Control with Power Amino Acids®

Dr. Scheele’s New Book:

George A. Scheele, M.D.

Dr. George A. Scheele, Creator of Factor4

Weight Control®, to combat obesity and

metabolic disease:

• Board Certified in Internal Medicine

• Princeton BA & John Hopkins MD

• Professor at Rockefeller University, Yale

University School of Medicine and Harvard

Medical School.

• Two time Nobel Associate (1974 & 1999)

• First to figure out how to separate all the

proteins in the human body (est. 20,000) by

inventing 2D gel electrophoresis

“As a medical doctor with over 30 years of

research, my personal mission is to reduce

worldwide obesity and metabolic disease. That is

why I created Factor4 Weight Control®.”

– George A. Scheele, MD

Meet Dr. Scheele

The Obesity Cure

Resolve the Long-Standing Diet Wars

• High protein/fat diets of Atkins

• Low fat diets of national policy

AIM: To Resolve the Obesity Epidemic

Call Attention to The Obesity Epidemic

Since 1980:

• Adult obesity has doubled (2x)

• Childhood obesity has tripled (3x)

• Morbid obesity has sextupled (6x)

Provide a New Approach to Weight-Loss Health

Book Purpose:

Solid Scientific Research Estimated $50 Billion of NIH Support Over 50 Years in

Digestive and Metabolic Health:

The Obesity Cure Connects the Dots

For the Clinical Breakthrough

The Basic Science

The Cure

Dietary Causes of Obesity

• Excess calories in a sedentary society

• Excess saturated & trans fat

• Excess salt

Weight Loss Paradox Explained

Contributory Factors:

Root Causes:

• Excess refined sugars & carbohydrates

• Protein Deficiency Syndrome – New!

Sugar is Addictive

• Dependency

• Cravings

• Withdrawal symptoms

• Yo-Yo metabolism (3 meals & 3-4 snacks per day)

Hallmarks of Sugar Addiction:

Hallmarks of Sugar Pathology • Increased levels of sugar & insulin in blood

• Insulin resistance to protect cells

• High blood insulin levels shut off fat metabolism

• Forever high insulin levels: Fat Forever!

The Modern American Diet (MAD)

Sugar Consumption Increased

• Over the past 100 years daily sugar consumption has increased more than

10-fold, (from 2 to 22 teaspoons per day)

• Sugar soda drinks have increased in size from 8 oz to 12 oz to 20 oz to 64 oz

• HFCS is responsible for increasing obesity rates in America since 1980

• HFCS & sugar show multiple toxic effects at high concentrations:

Glycation of proteins lead to cross-linked proteins called Advanced

Glycation Endproducts (AGEs)

The immune system seeks to destroy these foreign-looking bodies

Resulting inflammation leads to endothelial plaques and arteriosclerosis

• In 2011 two fifteen year old girls required liver transplants in UCSF for fatty liver

resulting in cirrhosis

Sugar: Pure, White & Deadly

In Higher Dosage Sugar is Toxic:

Mayor Bloomberg displays

the amount of sugar

contained in soda drinks

Sugar Addiction

• Consumers addicted to HFCS

• Food Industry addicted to profits

• Farmers addicted to government subsidies to

grow corn ($3.5 billion a year)

The Perfect Storm:

Sugar Leads to Fat Stored in 3 Places

• Fat depots throughout the body

• Fat in the Liver

• Fatty plaques throughout the arterial system

Result: Worldwide Obesity & Metabolic Disease

Selective Protein Deficiency Syndrome

2-Dimensional Gel Analysis:

A: Health

Normal Protein Pattern

Normal body weight

B: Selective Protein Deficiency Syndrome

Positive Charged Proteins Reduced by 90%

Within 12 days (gain in body weight)

C: CORRECTION with Factor4 Weight Control®

Power Amino Acids® correct protein deficiency

(Body weight returns to normal)

High Carb Diets Cause Protein Deficiency

Maintain Your Protein Team To Burn Fat

Power Amino Acids

• Essential amino acids

• Positive-charged amino acids

• Satiety amino acids

Free Amino Acids Absorbed Early (10-90 minutes):

Protein-Bound Amino Acids Absorbed Later (1-4 hours)

• Essential amino acids (9)

• Non-essential amino acids (11)

Early, Sustained & Enhanced Nutrition

Plus: Amino Acids Enhance Protein Nutrition

• Power Amino Acids increase protein digestion

& Amino acid absorption 6-fold

The Solution

• Curb appetite for refined sugars, processed

carbs, and fat

• Satisfy hunger with minimal calories

• Correct deficiencies in positive-charged

amino acids, proteins & metabolic pathways

to optimize fat metabolism

Power Amino Acids® Correct All Dietary

Causes of Obesity:

A Weight Loss Strategy That Works!

Bottom Line

Exploit nature’s feedback mechanisms to:

• Suppress appetite to avoid food cravings

• Burn fat to reduce excess body weight

• Build muscle to improve body definition

• Boost energy to tackle life

Power Amino Acids®

Scientific Research Reveals a New & Better Approach

to Weight Control and Metabolic Health:

Power Amino Acids® Essential for Weight Control!

The Product

Health & Wellness Innovation at its Best

* Claims have not been reviewed by the FDA

Timeline of Weight Loss Success

• “Sweet tooth” lost within the first few days

• Appetite suppression (comfort, satisfaction and well-being)

recognized within a few days

• Body rebuilt with pep, energy, activity, stamina &

endurance during the first month

• Body fat begins to decrease in the first week but initially

offset by increase in muscle mass

• Clothes fit better within weeks

• Body scale weight begins to decline shortly thereafter

• Weight loss adjusts when normal body weight achieved

Just a Matter of Time

Before You Meet Your Weight Loss Goals!

F4 Shake & Smoothie Strategies

• 3 to 4 shakes per day to optimize weight loss:

Meal replacement strategy for breakfast (smoothie)

Portion control for lunch (Half lunch with shake)

Snack control (shakes in lieu of snacks, particularly at night)

• Normal dinner with protein source & 2 vegetables

• Replace sugar drinks with Factor4 shakes

• Lose 5 to 10 pounds per month

• Some lose 10 to 20 pounds per month

Daily Routine for Weight Loss Strategies:

Maintenance Strategy:

• 2 shakes per day to sustain weight control

Bon Voyage to Good Health

Optimize Weight Loss Health

• Avoid sugar, processed carbs and excess salt

• Boycott cellophane foods made by the Food

Industry

• Boycott HFCS drinks made by the beverage

industry (soft drinks, energy drinks, fruit juices)

• Drink Factor4 shakes to tame appetite, satisfy

cravings, boost energy, normalize body weight,

and ensure nutritional health

Four Simple Tips to Normalize Weight:

Your Weight Loss Goals Achieved!

Weight Loss Study

• History: 25 subjects with Chronic overweight

disorders for 20-30 yrs. (historical controls)

• Within 3 months 96% of subjects lost weight

• Weight loss results:

Weight Loss Significance:

FDA Requires a 5% Loss in Body Weight in 12 Months

Conducted in 2007:

Endpoints 3 months 6 months 12 months

Weight loss in

pounds 8.4 lbs 16.2 lbs 33.4 lbs

% body weight

loss 4.5% 8.2% 16%

Weight Loss Performance

Factor4™ Outperforms Popular Diet Plans:

112 month results

NovaLife

312 month results

JAMA, March, 2007

Diet Plan Weight Loss

Factor4 Weight

Control®1

33 lbs

Factor4 Weight

Control®2

16 lbs

Atkins3 10 lbs

National

Guidelines3

6 lbs

Dean Ornish3 5 lbs

Zone3 3.5 lbs

26 month results

NovaLife

Obesity & Metabolic Syndrome

• Selective protein deficiency leads to a wide variety of

chronic degenerative disease

• Overweight disorders & obesity exist in a spectrum of

metabolic diseases associated with Metabolic Syndrome

• Includes chronic degenerative diseases that are

responsible for accelerated aging and early death

• Obesity is the most obvious manifestation of Metabolic

Syndrome

Overweight Disorders are Part of the

Metabolic Syndrome:

Two Epidemics: Obesity & Metabolic Disease

Epidemic of Metabolic Disease

Number of Cases in the US alone:

Disease Incidence

Overweight disorders 150 million

Obesity 75 million

High blood pressure 34 million

High cholesterol & TGL 30 million

High blood sugar 90 million

Type 2 Diabetes 30 million

Cardiovascular disease 57 million

Autoimmune disease 50 million

Cancer 18 million

Osteoarthritis 20 million

Gallstones 19 million

America Challenged with Chronic Degenerative Disease!

The Conclusion

Bon Voyage to Normal Body Weight,

Metabolic Health, and Anti-Aging Health

with

Power Shakes & Smoothies

Containing Power Amino Acids®

Look Younger, Live Longer & Feel Better

With Power Amino Acids®

www.factor4health.com

The Scientific Evidence

Power Amino Acids®:

• Suppress appetite centers in brain & stomach

• Correct the food-chain deficiencies in essential and positive-charged amino acids

• Close the food chain gap to increase metabolism

• Rebalance protein health between positive-charged and negative-charged proteins (selective protein deficiency syndrome corrected)

• Reset metabolic pathways to burn fat

Power Amino Acids® Stimulate

Weight Loss and Sustained Weight Control