sakura webinar series competitor update single slide ... · target customers he 600 •innovators...
TRANSCRIPT
Sakura webinar seriesCompetitor update Single slide stainer VENTANA HE 600
Anamaria Grigore
Strategic Product Manager Staining, Coverslipping and Digital Imaging
Sakura webinar series
Goal: Continue to extend and protect our leadingposition in routine Staining & Coverslipping
• Use phone line if your online audio is poor
• Lines are muted
• Post your question, a selection of the questions will be answered at the end
• You will receive a copy of this presentation
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Today’s presenter:
Name: Anamaria GrigoreFunction: Strategic Product Manager Staining, Coverslipping and Digital Imaging
Staining spectrum
Staining
Routine H&E
IHC
Special stainsDNA-RNA:
In situ hybridization
Staining spectrum
Staining
Routine H&E
IHC
Special stainsDNA-RNA:
In situ hybridization
Tissue groups or specific parts
confirm type and future treatment
Proteins on cell level, mostly used to specify
cancer type
Specific genes or dna defects
General morphology qualitative diagnosis
2 staining methods
Single slide staining
• Each slide treated like an individual specimen
Dip & Dunk (linear) staining
• Batch of slides immersed in a bath of staining solution
Ventana HE600
Throughput & Time to first result
Drying oven
Customizable protocols
Ventilation needed
Power supply
Waste disposal
Eco friendly as option
Glass coveslipping
Recyclable reagent bottles
Caregiver
Values & benefits Single slide staining (Roche HE600)
Quality Safety Lean
Single slide stainer Close platform RFID technology
Recyclable reagent bottles No cross contamination due
to staining RFID technology
Validated protocol Change of reagents during a
run Caregiver remote support Minimum end user
maintenance
Values & benefits Prisma Film
High throughput/speed 1 Preventive Maintenance
(PM) per year of 4 hours Standard power supply
Open platform (both H&E and special stains)
Coverslipping choice (glass of film)
Choice of reagents and slides
Proven technology High installed base >1000
units in SFE territory MTBR›52 weeks
Productivity Flexibility Reliability
• Chance of cross contamination is very small (0.01% to 1.2% of slides)1
• Most contamination takes place at Grossing table and during Microtomy (water bath) Processing and Staining & Coverslipping has no significant impact. 2
• Conclusion: Changing to Single Slide Staining will not bring significant benefits to overcome cross contamination
Grossing Processing Embedding Microtomy Staining & Coverslipping
Truth or fiction:Cross contamination reduction
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1 Layfield LJ, et al, Extraneous Tissue A Potential Source for Diagnostic Error in Surgical Pathology, Am J Clin Pathol. 2011; 136(5):767-772)2 Gephardt GN, and Zarbo RJ., Extraneous Tissue in Surgical Pathology, Arch Pathol Lab Med. 1996; 120: 1009-1014
30% 60%
Truth or fiction:Cross contamination reduction
HE600 concept looks great, yet…
• Sponsored studies by Roche were performed with new charged slides ,not reflecting daily practice
• Chance of cross contamination in staining is very small (confirmed by many studies and customers)
• Most contamination takes place at grossing, embedding, microtomy
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Target customers HE 600
• Innovators and early adopters ≈ 15% of the market
• Small and medium labs
• Symphony accounts for replacement
• Roche reference sites
• Customers scared of cross-contamination
Target customers Prisma & Film
• Early and late majority ≈ 70% of the market
• Small, medium and large labs
• DRS and SCA customers
• All customers that want/ need a reliable and flexible
solution for staining & coverslipping
Prisma & Film Value proposition
Value proposition
Small labs Flexibility/H&E and special stains in one/quality/reliability
Medium and large labs High throughput and speed/quality/reliability
Customers scared of cross-contamination Floaters represent a potential source of diagnostic error and occur in 0.01% to 1.2% of slides*Customers for Tissue-Tek AutoTEC a120, Autosection
All labs Productivity/Quality/Reliability
*A Potential Source for Diagnostic Error in Surgical Pathology Lester J. Layfield, MD,1 Benjamin L. Witt, MD,1 Kenneth G. Metzger, HTL(ASCP),2and Gina M. Anderson, HT(ASCP)2
Comparative analysis
Prisma & Film Roche HE 600
Throughput and speed √ -
Reliability √ Not yet proven
H&E & special stains & cytologyin one platform
√ -
Consistency of results √ √
Choice of reagents, slides, coverslipping method √ -
Environmental friendly (reagents and fumes) √ √
LIS connectivity√
√ only with VENTANA VANTAGE or VENTANA Connect Software
STAT in coverslipping √ -
Take away message
Continue to extend and protect our leadingposition in routine Staining & Coverslipping
Wrap-up
• You will receive a copy of this presentation and the publication on floaters and cross contamination.
• For unanswered questions please contact [email protected]
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