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Page 1: Annual Report 2012 - Karolinska Institutet · Annual Report 2012 Karolinska Institutet Ref. no. 1-18/2013 Karolinska Institutet is one of the world’s leading medical universities

me

Annual Report 2012

Page 2: Annual Report 2012 - Karolinska Institutet · Annual Report 2012 Karolinska Institutet Ref. no. 1-18/2013 Karolinska Institutet is one of the world’s leading medical universities

Annual Report 2012

Karolinska Institutet

Ref. no. 1-18/2013

Karolinska Institutet is one of the world’s leading medical universities. Its mission is to contribute to the improvement of human health through research and education. Karolinska Institutet accounts for over 40 per cent of the medical academic research conducted in Sweden and offers the country´s broadest range of education in medicine and health sciences. Since 1901 the Nobel Assembly at Karolinska Institutet has selected the Nobel laureates in Physiology or Medicine.

Cover photo

Anna Eklöf has studied speech and language pathology at Karolinska Institutet. In 2012, the Swedish National Agency for Higher Education evaluated every study programme in speech and language pathology in Sweden and Karolinska Institutet got the highest grade.

Speech therapists specialise in communication disorders as well as swallowing disorders and the therapy of these disorders.

Speech and language pathology studies disorders in human speech, how these disorders arise, what causes it and how to manage them.

By injury or disease, people can be affected to the point where it isdifficult or impossible to communicate with others. The ability to communicate through language is absolutely vital for the quality of life..

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Annual Report 2012

Karolinska Institutet

Ref. no. 1-18/2013

Karolinska Institutet’s education and research 2012

Söder Hospital183FTE studentsResearch SEK 40 million 41 FTE employees

“Research” indicates total assets, excluding premises and funding for medical training and research.

KI Solna Campus1,478 FTE studentsResearch SEK 1,548 million 1,938 FTE employees

KI Huddinge Campus with Karolinska University Hospital, Huddinge3,110 FTE studentsResearch SEK 921 million 1,087 FTE employees

Karolinska University Hospital, Solna839 FTE studentsResearch SEK 1,282 million1,101 FTE employees

Danderyd Hospital235 FTE studentsResearch SEK 33 million26 FTE employees

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4 Karolinska Institutet Annual Report 2012

Karolinska Institutet in brief 5Key ratios 6Karolinska Institutet’s structure 7 President’s comments on the year 8Results of operations 10Internal management and control 11

Bachelor’s (first-cycle) and master’s (second-cycle) education 12

Research and doctoral (third-cycle) education 27

Common to all operations 39

Collaboration and innovation 41

Internationalisation 46

Quality 47

Equal opportunities 48

Sustainable development 49

Human resources and competence supply 50

Infrastructure 56

Financial report 58Notes 71The university board 80Appendix 84

Figures in the tables provided in this annual report have been rounded up, so that the totals, etc., do not appear consistent.

Table of contents

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Karolinska Institutet Annual Report 2012 5

Karolinska Institutet in brief, 2012

Bachelor’s and Master’s education

Programmes with number of degrees awarded

Professional qualifications• Occupationaltherapy 60• Audiology 18• Midwifery 56• Biomedicallaboratoryscience 52• Speechandlanguagepathology 4• Medicine 272• Optometry 29• Psychology 18• Psychotherapy 14• Radiographynursing 39• Physiotherapy 107• Nursing 14• Specialistnursing 419• Dentalhygiene 38• Dentistry 70• Dentaltechnology 13

General Qualifications• Universitydiplomas 1• Bachelor’s 351• Master’s(oneyear) 159• Master’s(twoyear) 137• BroadMaster’s(oneyear) 7

Total 1,878

(No.ofindividualstudents:1,668)

KIalsoarrangessingle-subjectcoursesforsupplementaryqualificationsandfurthereducation.

5,885full-timeequivalent(FTE)studentsand5,307annualperformanceequivalents(APEs).

305incomingstudentsand139outgoingstudentsonexchangeprogrammes.

Research and education – doctoral level

• 5295articlespublished,includingothers(2011)• 2,165activedoctoralstudents(≥10%active)• 359completeddoctoraldegreesand14licentiatedegrees

Asset management (market capitalisation)

• SEK259millioninfundmanagement• SEK1,235millioninfoundationmanagement

Staff

4,192employees(FTE),comprising:• 367professors(27%)• 159seniorlecturers(58%)• 161postdoctoralfellows(51%)• 159lecturers(75%)• 793seniorresearchfellows(53%)• 572doctoralstudents(64%)• 1,068labandtechnicalstaff(69%)• 913administrativestaff(84%)Note:Thefiguresinbracketsgivethepercentageofwomen.Totalnumberofwomen:2,662(64%)

Funding

Total:SEK5,646million,ofwhich:• 2,566directgovernmentfunding• 730researchcouncils• 389othergovernmentagencies• 738Swedishfoundationsandorganisations• 197Swedishcompanies• 540countycouncilsandmunicipalities• 432foreignfinanciers,including –194EU –162foundationsandotherorganisations –76companies• 55financialrevenue

Premises

Totalarea:213,881m2

Cost:SEK667million

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6 Karolinska Institutet Annual Report 2012

Key ratios2012 2011 2010 2009 2008

Education and research

FTE, full time equivalent, students1 5,885 5,815 5,524 5,595 5,336Cost per FTE student (SEK thousand)* 154 146 144 143 143APEs1 5,307 5,351 5,050 5,012 5,052Cost per APE (SEK thousand)* 170 159 157 159 151Number of fee-paying students 34 10New doctoral admissions 438 409 450 420 420– women 57% 61% 62% 61% 60%– men 43% 39% 38% 39% 40%Doctoral students, total > 10% activity 2,165 2,133 2,076 2,028 2,080– women 61% 62% 62% 61% 61%– men 39% 38% 38% 39% 39%Doctoral students with employment (FTEs) 572 544 519 515 491Doctoral students with grant (FTEs) 380 340 347 342 362Average study time, licentiate students (net) 3.03 2.56 2.05 2.38 2.19Average study time, doctoral students (net) 4.26 4.21 4.21 3.94 3.83Doctoral degrees awarded 359 349 367 392 352Licentiate degrees awarded 14 14 21 17 15Peer-reviewed scientific publications ** 4,090 3,901 3,801 3,789Cost per peer-reviewed scientific publication (SEK thousand)*** 1,043 1,062 1,022 925

Staff

FTEs 4,192 4,109 3,944 3,875 3,453Average staff 4,716 4,699 4,545 4,382 3,988Teaching staff: (FTEs) 846 845 801 812 753– women 46% 47% 46% 47% 48%– men 54% 53% 54% 53% 52%Teaching staff with doctoral degrees (FTEs) 714 707 665 634 573– women 41% 41% 40% 38% 38%– men 59% 59% 60% 62% 62%Professors (FTEs) 367 347 331 328 316– women 27% 26% 24% 21% 20%– men 73% 74% 76% 79% 80%

Finance

Revenue, total (SEK million), of which 5,646 5,340 5,253 4,880 4,476

Bachelor’s and Master’s education (SEK million) 954 926 851 853 850

– direct government funding (%) 87% 87% 89% 89% 89%

– external revenue (%) 13% 13% 11% 11% 11%

Doctoral education and research (SEK million) 4,692 4,415 4,402 4,027 3,626

– direct government funding (%) 37% 37% 36% 33% 36%

– external revenue (%) 63% 63% 64% 67% 64%

Costs, total (SEK million) 5,506 5,188 4,994 4,734 4,325– Staff 52% 53% 52% 53% 51%– Premises 12% 11% 11% 12% 12%Premises costs2 per m2 (SEK) 3,118 2,916 2,761 2,791 2,696Balance sheet total (SEK million), of which 5,017 4,899 4,658 4,105 3,626– unexpended grants 2,313 2,277 2,224 2,030 1,652– change in capital for the year 108 145 255 149 164– administrative capital (incl. change in cap. for the year) 1,289 1,196 1,079 812 665– of which subsidiaries (KI Holding AB) 82 97 129 122 119

1 Excluding contract education and contracted courses.2 As stated in the revenue statement. * Including costs incurred within funding for medical training and research and the dental care centre. ** Figure not given owing to delay in registration, which would otherwise distort the statistics. The figures for 2008–2010 have also been adjusted due to the aforementioned delay in registration. Also affects cost per publication.*** Including costs incurred within funding for medical training and research.

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Karolinska Institutet Annual Report 2012 7

Karolinska Institutet’s structure 2012

PRESIDENTManagement Group

Board ofHigher Education

UNIVERSITY BOARD Internalaudit

University Administration

University Library

KI Holding AB

Board ofDoctoral Education

Board ofResearch

Comparative Medicine

Councils and Committees

22 DEPARTMENTS

KI Solna CampusDepartment of cell and molecular biology (CMB)Department of physiology and pharmacology (FyFa)Department of learning, informatics, management and ethics (LIME)Department of medical biochemistry and biophysics (MBB)Department of medical epidemiology and biostatistics (MEB)Department of microbiology, tumor and cell biology (MTC)Department of environmental medicine (IMM)Department of Neuroscience (Neuro)

KI at Karolinska University Hospital (Solna) and Danderyd HospitalDepartment of public health sciences (PHS)Department of clinical neuroscience (CNS)Department of clinical science, Danderyd Hospital (KI DS)Department of woman and child health (KBH)Department of medicine, Solna (MedS)Department of molecular medicine and surgery (MMK)Department of oncology–pathology (OnkPat)

KI Huddinge Campus with Karolinska University Hospital Huddinge and Söder HospitalDepartment of biosciences and nutrition (BioNut)Department of clinical science and education, Söder Hospital (KI SÖS)Department of clinical sciences, intervention and technology (CLINTEC)Department of laboratory medicine (LABMED)Department of medicine, Huddinge (MedH)Department of neurobiology, care sciences and society (NVS)Department of dental medicine ( DENTMED)

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8 Karolinska Institutet Annual Report 2012

Strong international presenceAsIwritethisforeword,theinaugurationceremonyformypresidencyhasrecentlytakenplaceattheCityHall.Ihavebeencommissionedwiththeleadershipofastrongandexpandingmedicaluniversityinaperiodofgreatchange,whichbearsthehallmarkofmypredecessor.IwouldthereforeliketoespeciallythankProfessorHarrietWallberg-HenrikssonforallheraccomplishmentsasPresidentofouruniversity.

KarolinskaInstitutet(KI)istodayaleadingresearchuniversitywithastronginternationalpresenceandhighvisibilityinSwedishsociety.Itiswithpleasureandpride,butalsohumility,thatInowacceptthiscommissionasKI’stwenty-firstPresident.

Unique research initiative Thegovernment’slatestresearchandinnovationbillprovidesSwedenwithauniqueopportunitytoincreasetheinternationalcompetitivenessofourresearch.Togetherwiththepreviousbill,additionalannualfundsofninebillionhavebeenestimatedandasignificantportionhavebeenallocatedtolifesciences.Itisachallengeandagreatresponsibilityfortheeducationalinstitutionsandotherresearchactorstochanneltheseresourcestowardsactivitiesthatprovidethehighestqualityresearch.

SciLifeLab is becoming a national resourceThisyear,thegovernmenthasdecidedtostrengthenthefocusonScienceforLifeLaboratory(SciLifeLab)asanationalresourceforlarge-scalebasicandtranslationalcutting-edgeresearchwithinmolecularlifescience,medicineandenvironment.Thegovernment’sinvestmentisexpectedtoreachSEK300millionby2016.

InApril2012,AstraZenecajoinedtheinvestmenteffortsinSciLifeLabpreviouslydeterminedbythegovernmentandtheKnutandAliceWallenbergFoundation.Themainpriorityistosupportresearcher-initiatedtranslationalandpatient-orientedresearchwithinneurosciences,cancer,respiration,inflamma-tion,infectiousdiseases,diabetes,othermetabolicdisordersandcardiovasculardiseases.Theaimistoincreasetheunderstan-dingofdiseasemechanismsandvalidatenewtargetmoleculesfordiagnosisandtreatment.

Programme evaluationIn2012,theSwedishNationalAgencyforHigherEducationexaminednineofKI’sprogrammes;twoofwhichhavereceivedthegradeofveryhighquality,fivehavereceivedthegradeofhighqualityandtwoweregiventhegradeofpoorquality.

ThehighestgradewasachievedbytheSpeechandlanguagepathologyprogrammeandtheBachelor’seducationinPsycho-logy,whichisaverypleasingresult.However,allprogrammesatKIshouldconstitutehighqualityeducationandthelong-termgoalisforatleast50percentofallprogrammesinthefuturetoobtainthegradeofveryhighquality.Specificinterventionmeasureshavebeendevelopedfortheprogrammesthatwere

ratedpoorquality,butKIisnowworkingwithfocusedeffortstoimprovequalitywithinallprogrammes,includingelementssuchaspedagogicaldevelopmentandincreasedrelatedresearch.Inconnectiontothis,IwouldliketothankalltheKIemployeeswhoparticipatedinvariouswaysintheevaluationwork.

Collaboration with the County CouncilInthepastyear,thecooperationwithStockholmCountyCouncil(SCC)hasbeenintensified,forexamplethroughProject4D(fourdiagnoses),inordertocreatebetterconditionsforclinicalresearchanddevelopmentwithinhealthandmedicalcare.Thisappliestotheareasofheartfailureandthrombo-embolism,arthriticdiseases,type2diabetesandbreastcancer,andinformatics.Theaimoftheprojectisalsotoinvestigatehowtheresultsofclinicalresearchcanbeconvertedmorerapidlyintonewandimprovedtreatments,aswellastostrengthencollaborationwithpharmaceuticalandbiotechnologycompanies.

Mayo ClinicThecollaborationwiththeMayoClinicintheUnitedStateshasdeepened.Duringtheyear,jointmeetingstookplaceinStockholmaswellasinRochester,Minnesota.

Ajointoperationalsteeringgrouphasbeencreatedwiththetaskofstructuringandplanningfuturecooperation.Asajointventure,anannouncementwasmadeattheendoftheyearregardingtheopportunitytoapplyforfinancialaidfortravelinvolvedwithcooperationprojectswithinresearch,education,innovationandadministration.ThisisonlythefirststepandIlookforwardtocontinuedclosecooperationandnewinitiativesinthecomingyear.

Major investments in infrastructureConstructionworkhasbeenon-goingthroughouttheyear,bothwithourspectacularauditoriumandtheWiderströmBuilding,whichwillhousethedepartmentsofLearning,Informatics,ManagementandEthics(LIME)andPublicHealthSciences(PHS).InclosecooperationwithSCC,theintensiveprocessofdesigningabrandnewuniversityhospitalwillcontinue,whichwillincludealargelaboratorybuildingfortranslationalresearchwithafocusonprevalentdiseases.ThedesignofBiomedicum,whichwillbecomeoneofEurope’slargestresearchlaboratoriesforbiomedicalbasicresearch,isnowalmostcomplete.

DonationsKIhasreceivedanumberofdonationsin2012,whichcontributetoourlong-termresearchinavitalway.Iwanttotakethisopportunitytomentionafew:• Erling-PerssonFamilyFoundation,MagneticResonance Imaging(MRI)scannerforCardiovascularResearch (SEK28million)

President’s comments on the year

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Karolinska Institutet Annual Report 2012 9

• StichtingafJochnickFoundation,researchonthe underlyingcausesofdiabetes(SEK15million)• FredrikLundberg,researchonarterialaneurysm (SEK13million)• BjörnochLenaUlvaeus,researchonblooddiseases (SEK3million)• MatsSundin,collaborationwiththeUniversityofToronto onchildren’shealth(SEK2million)

Inadditiontotheselargerdonations,wehavealsoreceivednumerousdonationsandgiftsofloweramountsandIwouldliketoextendawarmthankyoutoallourdonorsforyourfinancialsupportandcommitmenttoKI.

The futureIwishtohighlightthreekeyissuesrelevanttoKI’sfuture.WeneedtostrengthenKI’spositionasaleadinginternationalresearchuniversity.Wethereforeneedtoallocateadditionalresourcestosupportingthereallypromisingyoungresearchersatthebeginningoftheircareer,inordertoensureregrowthandincreasetheopportunitiesforinternationalrecruitment.

Wealsoneedtostrengthenourfirst-cycleprogrammes,sothatwecanattractthemostenergetic,enthusiasticandcreativestudentsfromallpartsoftheworld.Thesamerequirementsofexcellencethatweplaceonresearchmustbeplacedonourprogrammes.

Furthermore,weneedtodevelopourinteractionwithhealthandmedicalcare.ThehealthcarelandscapewithinwhichKIoperatesinisundergoingrapidchange.Thenumberofindividualhealthcareprovidersisgrowingrapidly,whichcanleadtofragmentationandtherebyjeopardisetheepidemiological,clinical,andtranslationalresearchthatconstituteimportantpartsofKI’sinternationalcompetitiveability.Consequently,KIneedstodevelopanewstrategyforcollaborationwiththehealthcaresystem.

Finally,IwouldliketopointoutthatKI’ssuccess–past,presentandfuture–issolelythankstomanyindividualemployees’creativity,brilliance,enthusiasm,competitivedesire,loyaltyand,notleast,hardwork.IthereforelookforwardwithgreatconfidencetocontinuedpositivedevelopmentforbothresearchandeducationatKI.

AndersHamsten President

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10 Karolinska Institutet Annual Report 2012

The Annual Reports and Budget Documentation OrdinanceInaccordancewithChapter3,Section1oftheAnnualReportsandBudgetDocumentationOrdinance(SFS2000:605),theauthoritiesshallcommentontheresultsofoperationsrelativetotheinformationsetforthintheauthority’sinstructionsand,whereappropriate,whatthegovernmenthasspecifiedinpublicserviceagreementsorinanotherdecision.

Theprofitandlossaccountingshouldprimarilyrelatetohowtheoperation’sperformancehasevolvedintermsofvolumeandcosts.

Thereportmustbesubmittedaccordingtotheclassificationdeterminedbytheauthority,unlessthegovernmenthasdecidedotherwise.

Instructions for higher education institutions – the Higher Education ActThepublicserviceagreementof2012foruniversitiesandhighereducationinstitutions,stipulatesthattheoverallgoalsforuni-versities’andhighereducationinstitutes’operationsarefoundintheHigherEducationAct.

TheActstatesthatthetwomaintasksofuniversitiesandhighereducationinstitutionsareeducation,whichhasascientificorartisticbasisaswellasreliableexperience,andalsoresearchandartisticdevelopmentalongwithotherdevelopmentwork.

Alsoincludedinthehighereducationinstitutions’tasksisthattheymustcollaboratewiththesurroundingsociety,provideinformationontheiroperationsandendeavourfortheirresearchresults,developedattheinstitution,tobeappliedinaneffectivemanner.

Operationsshouldalso,forexample,beconductedinsuchaway• thatthereisacloserelationshipbetweenresearchand education,• thatscientificcredibilityandgoodresearchpracticesare safeguarded,• thatahighqualityisachievedwithintheoperations,• thattheavailableresourcesareutilisedeffectively,• thatsustainabledevelopmentispromotedwithinthe operations,• thatequalitybetweenwomenandmenisalwaysobserved andpromoted,and• thattheoperationspromoteanunderstandingofother countriesandinternationalconditions.

Furthermore,studentsshouldbegiventherighttoinfluencetheeducation,andtheeducationalinstitutionsshouldactivelypromoteandbroadenthescopeofrecruitment.

Strategy 2012KIhasestablishedadevelopmentstrategyfor2010–2012:Themissioninvolvescontributingtotheimprovementofpeople’shealththroughresearchandeducation.

ThevisionisforKItobeoneoftheworld’sleadinguniversitieswithinthemedicalfield.

Itisonthebasisofgoalsandreportingrequirementsinthereferredtodocumentsthatthisannualreportisdeveloped.

Results of operations

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Karolinska Institutet Annual Report 2012 11

KIisencompassedbytheInternalControlOrdinance(2007:603).Inviewoftheestablishedriskanalysisandtheimplementedandplannedworkwithapprovedcontrolactivities,theBoardofKarolinskaInstitutet’sassessmentintheannualreportisthatinternalcontrolatKIissatisfactory.

Thisyear’sworkhasbeenbasedonpreviouslyagreedrulesandguidelinesforinternalcontrolatKI,whereamorethoroughriskanalysishasbeencarriedoutduringthefinancialyear2012.ThedeparturepointfortheriskanalysishasbeenKI’smissioninaccordancewiththeHigherEducationActandOrdinance,publicserviceagreementsandtheUniversity’sdevelopmentstrategy.Inaddition,significantobservationsinconjunctionwithinternalandexternalauditinghavebeenconsidered.

Thisyear,theBoardofKarolinskaInstitutethasidentifiedelevenriskareaswheredecisionshavebeenmaderegardingtargetedcontrolactivities:namely,thelossofdegree-awardingpowers,inadequateteacheraccesswithineducation,thelackofmoderntechnologyplatformsandtoolswithineducation,limitedopportunitiesforclinicalresearchandeducation,scientificfraud,restrictiveregulationsonregistrydataandanimalactivity,thelackofresearchdocumentation,inadequatemedicalinformaticsforKI/SCC,insufficientadaptationatKIbasedonchangesinhealthcare,thelackofcompliancewiththePublicProcurementActandreclamationduetopoormanagementoffundsandreportingtoexternalfinanciers.

Duringtheyear,previouslyapprovedcontrolactivitieshavebeenfollowedupontwooccasions,wheresignificantresultshavebeenreportedtotheBoardofKarolinskaInstitutet,includingthedevelopmentofKI’sinformationsecurityandIT.

Aframeworkforinformationsecuritymeasureshasbeendevelopedwithcomprehensivepreparationsforimplementation.Intheautumnof2012,twoseniorpositionswerealsofilledwithininformationsecurityandIT.

On13February2012,theSwedishNationalAuditOfficesubmittedanauditreportcontainingobservationsrelatingtotheprocurementandpurchasingprocesswhereKI,initsofficiallettertotheNationalAuditOfficeon23April2012,hadreportedplannedandimplementedmeasureswithinthearea.Duringtheyear,workhascontinuedtosignificantlystrengtheninternalcontrolsinordertoensurethatthePublicProcurementActisfollowed.Furtherdevelopmentworkisrequired.

Inadecisionon29May2012,theOfficeoftheChancellorofJusticewasextremelycriticalofKIfordeficienciesinrecordkeepingandcaseadministration.Throughoutthefiscalyear,majoreffortshavebeeninstitutedinordertoovercometheseshortcomings.Thesemeasureshaveincludedtheclarificationofresponsibilities,traininginitiativesandareviewoftheoperations’registration.Preparationshavebeenmadefortheintroductionofanewregistrationsystemandelectronicworkflowmanage-mentsystemwhichwillbeupandrunningin2013.

Inordertoimprovetheefficiency,qualityassuranceandintegrationoftheinternalcontrolprocess,aswellasoperationalplanningandmonitoring,theBoardofKarolinskaInstitutetreachedadecisionon20February2012regardingactivitiesinKI’sannualplanfor2012–2013.TheworkhasresultedinclearerinstructionsforoperationalplanningandKI’sfirstcompre-hensiveoperationalplancontainingtasksandabudgetforthecomingyear.

Internal control

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12 Karolinska Institutet Annual Report 2012

Bachelor’s (first-cycle) and Master’s (second-cycle) education

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Bachelor’s and Master’s education

Karolinska Institutet Annual Report 2012 13

KarolinskaInstitutetisuniqueinSwedenwithrespecttoitsbroad,virtuallycomprehensiveprospectuswithinmedicineandhealthcare.

KIoffered40studyprogrammesduringtheyearandadvertisedover130separatesingle-subjectcourses.Thefocusoftheprospectusisonprogrammesthatleadtoaprofessionalqualificationaswellascontinuingeducationforthosewhoalreadyhaveaneducationwithinhealthandmedicalcare.

KIcontinuallyreviewsitsprospectusandhasinrecentyearsstrivedtoconcentratetheselectionofprogrammesonoffer.AnestablishedgoalisforKItoonlyofferprogrammeswithactiveresearchwithinthemainsubjectarea.KIisalsoendea-vouringtoadapttheprospectustothereceivers’needs,aswellasincreasetheproportionofprogrammesatthesecond-cyclelevel.

TherehavebeenfewnewinitiativesthisyearasKIhashadaperiodofover-production,whereinfundingsavingswillbeexhaustedforthenestfewyears.Twonewspecialistnursing

programmesinmedicalandsurgicalcarerespectivelywerelaunchedintheautumntermof2012.TheMasterProgrammeinHealthInformaticswasmodifiedpriorto2012andisnowaprogrammecomprisingajointdegreetogetherwithStockholmUniversity.Theaimistoprovidetheprogrammewithaclearerlinktotheon-goingresearchwithinthefieldatbothuniversities.

AsKIestimatesanover-productioninthenextfewyears,decisionshavebeenmadethataimtoadjusttheprospectustotheestablishedfundingcap.Duringtheyear,KIcommencedthephasingoutoftwobeginnersstudyprogrammes,DentalTechnologyandPublicHealthSciences.Decisionshavealsobeenreachedtosignificantlyreducethescopeofsingle-subjectcourses,butthiswillnotenterintoeffectuntil2013.

In2012,thebreakdownintodifferenttypesofprogrammesandcourses,aswellasthebreakdownofcoursesintofirst-cycleandsecond-cycle,remainedunchangedforthemostpartfrom2011,whichisillustratedinthetablesbelow.

Prospectus

Bachelor’s and Master’s courses(including courses settled against supplementary funding)

2009 2010 2011 2012

FTEs % FTEs % FTEs % FTEs %

Bachelor’s 3,603 64 3,423 62 3,480 60 3,554 60

Master’s 1,848 33 2,035 37 2,289 39 2,290 39

Unclassified 144 3 66 1 46 1 41 1

Total 5,595 100 5,524 100 5,815 100 5,885 100

Source: Ladok

Breakdown of programmes that lead to a general qualification, programmes that lead to a professional qualification and single-subject courses

2009 2010 2011 2012

FTEs % FTEs % FTEs % FTEs %

General qualification – beginner 328 6 264 5 248 4 211 4

General qualification – continuation 344 6 393 7 443 8 424 7

Professional qualification – beginner 3,939 70 3,726 67 3,832 66 3,976 68

Professional qualification – continuation 585 10 566 10 582 10 573 10

Single-subject courses 399 7 575 11 709 12 701 12

Total 5,595 100 5,524 100 5,815 100 5,885 100

Source: Ladok

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Bachelor’s and Master’s education

Karolinska Institutet Annual Report 201214

Wideningparticipationinvolvesboththerecruitmentofnewgroupsofstudents–withtheaimofreducingtherecruitmentimbalance–aswellasthecreationofgoodstudyconditionsforthosealreadystudyingattheuniversity.

During2012,KIintensifieditseffortswithregardtolanguagesupportforstudents,throughexpandinglanguagesupportinSwedish.Inaddition,KIofferslanguagesupportinEnglishstartingfrom2012.KIalsoofferslanguagesupportatadistance,anactivitythatisprimarilyaimedatstudentsstudyingabroad.Thepreviouslyavailableseminarseriesonscientificwritinghas,duringtheyear,beenprovidedwithinadditionalstudyprogrammes.Finally,KIalsooffersstudentsalectureseriesinstudyskillsandstressmanagement.

Aspartofeffortstowideningparticipation,KIhas,forexample,introducedstudentambassadors.ThestudentambassadorsvisitandpresentKI’srangeofactivitiesatuppersecondaryschoolswithinStockholmcounty.KIseeksasdiverseagroupofambassadorsaspossible,bothintermsofgenderandethnicity.Furthermore,KIcollaborateswithHuddinge,SolnaandTenstauppersecondaryschool,wherecollaborativeactivi-tiesareongoing.Theseactivitiesincludeelementssuchasinspi-rationallecturesandstudyvisits.AnotherimportantpartoftheworkwithwideningparticipationisthatKIoffersprospectivestudentstheopportunityto”shadowastudent”.

Professional qualification course for opticians

KIassessedthattherewasnoidentifiableneedtoinitiateaprofessionalqualificationcourseforopticiansin2012.

The students

Ingeneral,KI’sprogrammeshaveahighacceptanceratioandthisfigurehasincreasedsomewhatwhencomparedto2011.Thetotalnumberofqualifiedfirstchoiceapplicantshasincreasedbyslightlymorethantwopercentincomparisonwith2011.TheStudyProgrammeinMedicineandtheStudyProgrammeinPsychologyhavethehighestacceptanceratioatKI,aswellas

inanationalperspective.Followingafairlysignificantdeclinein2011–resultingfromtheintroductionoftuitionfees–theacceptanceratiofortheone-andtwo-yearMaster’sprogrammeshasincreasedagain,bothinthenationalandinternationaladmissionsrounds.

Widening participation

Acceptance ratio by programme type (qualified first-choice applicants)

2009 2010 2011 2012

Places Ratio Places Ratio Places Ratio Places Ratio

Beginner 986 4.8 1,142 5.1 1,297 4.6 1,245 4.9

Continuation - excl. Master’s (1/2 year) 678 2.1 511 2.9 618 3.1 674 2.8

Master’s (1/2 year) 225 2.8 334 2.9 362 1.9 325 2.3

Total 1,889 3.6 2,087 4.1 2,277 3.8 2,244 3.9

Sources: VHS (Swedish Agency for Higher Education Services), NyA Open

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Asshowninthediagrambelow,thepercentageofbeginnersunder24yearsofagehasincreasedsignificantlybetween2011and2012,and–withtheexceptionof2010–anincreaseisalso

notedincomparisontopreviousyears.Theincreaseinpercen-tageofyoungerstudentsmaybeduetothenewadmissionsandselectioncriteriaintroducedin2010.

StudentparticipationisanimportantpartofKI’sdraftinganddecisionmakingprocesses.StudentsatalllevelshavetheopportunitytoinfluenceKI’sdraftinganddecisionmakingbodies,includingKI’sManagementGroup.

Astrongstudentpresenceisparticularlyimportantinbodiesthathaveadirectresponsibilityformattersofeducation.KIthereforerequiresthatatleastonestudentrepresentativebepresentatmeetingsforsuchbodiestobequorate,providedthatastudentrepresentativehasbeenappointed.

In2012,womenconstituted68percentofthestudentrepresentativesindecision-makingbodies:KI’sBoard,theinternalexecutiveboardsandprogrammecommittees,anincreaseoffivepercentagepointscomparedwith2011.However,thedifferenceinnominaltermsissmall.Intheprogrammecommittees,thegenderdistributionis

representativeofthestudentpopulation–73percentbeingwo-men–whichisnotthecaseintheotheraforementionedbodies.Inordertopromotestudentinfluence,KIorganisesannualseminarsforstudentsactivewithinKI’sdraftinganddecision-makingbodies.StudentsareeducatedonapplicablelawsandprovisionsaswellasonKI’sorganisationalanddecision-makingstructure.Attheprogrammecommitteelevel,continuousdiscussionsareconductedontheimportanceofstudentinfluence.

KIhasanagreementwiththetwounionsattheUniversityregardingtheirresponsibilityforstudentparticipationandeducationalaffairs.Includedintheagreementisfinancialsupportforthesetasks,aswellasfortheStudents’andGraduateStudents’Ombudsman.Duringtheyear,anewagreementhasbeendrawnupfor2013–2015.

Breakdown by age

Student influence

Age distribution of beginners on beginner’s programmes 2012 Age distribution of beginners on continuation programmes 2012

0%

20%

40%

60%

80%

100%

2009 2010 2011 2012

< 24 years

25–34 years

>35 years

< 24 years

25–34 years

>35 years

< 24 years

25–34 years

>35 years

< 24 years

25–34 years

>35 years

0%

20%

40%

60%

80%

100%

2009 2010 2011 2012

< 24 years

< 24 years

< 24 years

< 24 years

25–34 years

25–34 years

25–34 years

25–34 years

>35 years >35 years >35 years >35 years

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Thetotalnumberofdegreesawardedhasdecreasedsignificantlywhencomparedto2011;from2,239to1,878.ThedecreaseisduetoKI–asaresultoflosingitsdegree-awardingpowers–havingnoadmissionstotheStudyProgrammeinNursingduring2009.Thisimpactsboththenumberofnursingdegrees

awardedandBachelordegreeswithnursingastheirmainfieldofstudy.Severalotherdegreeshaveincreasedinnumber.Thisyear,thefirstbatchofpsychologystudentsatKIgraduated.ThenumberofdegreesawardedperprogrammeisshowninTable7intheTablesappendix.

Degrees awarded

TheStudyProgrammeinPsychologyatKIbeganintheautumntermof2007with40places.Inthepublicserviceagreementfor2009and2010respectively,KIwasawardedanadditional15

beginnerplaces(7.5FTEstudents),whichmeansthattheplannednumberofbeginnerplacesis70.Intheautumnterm2012,84studentswereregisteredonterm1.

Admissions to the Study Programme in Psychology

Accordingtothepublicserviceagreement,KIistoreportthenumberofFTEstudentsonboththeMedicineandDentistryprogrammes.Theinformationisshowninthetabletotheright.ThewayinwhichthenumberofFTEstudentshasdevelopedovertimeispresentedinTable6oftheTablesappendix.

FTE students in the Study Programme in Medicine and Study Programme in Dentistry

Total number of FTE students in the Study Programme in Medicine and Study Programme in Dentistry 2012Study Programme in Medicine 1,516Study Programme in Dentistry 396

Source: Ladok

CommissionedworkatKIconsistsoftwoparts:contracteducationandcontractedcourses.

Therevenueforcommissionedworkhas,asshowninthediagramtotheright,decreasedsomewhatwhencomparedwith2011,andamountstooverSEK70millionin2012.Municipalitiesandcountycouncilsarethesinglelargestclients.

Commissioned work

Revenue from commissioned work, 2003–2012, excluding tuition fees

0

15

30

45

60

75

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Source: Agresso

Number of degrees awarded

Degree 2009 2010 2011 2012

Professional qualifications 1,488 1,416 1,466 1,223

General Qualifications 697 728 773 655

Total number of degrees 2,185 2,144 2,239 1,878

Total number of individuals 1,792 1,786 1,888 1,668

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Revenue from commissioned work divided by financier, 2012

County councils and municipalities 45%

Higher educational institutions 12%

Organisations and foundations 4%

Swedish companies 19%

Foreign 11% Other government agencies 9%

Source: Agresso

Intotal,revenuefromcontracteducationhasdiminished.Thisisduetoadecreaseintheextentofnon-accreditingcontracteducation.

Accreditingcontracteducationhashoweverincreasedcomparedto2011,bothintermsofrevenue,FTEstudentsandAPEs.Throughastrategicinitiativeaimedathealthcareproviders,furthercommissionshavebeengenerated.Anin-

creasehasbeenobservedinseveralsubjectfields,suchassocialpsychiatryandmedicine.Thisyear,theNationalBoardofHealthandWelfarehasbeenamajorclient,butthesecommissionsendedin2012.In2013,thecurrentrecessionisexpectedtoresultinadecreaseintheextentofaccreditingcontracteducation.

Contract education

FTE students and APEs in contract education

2009 2010 2011 2012

FTE students 181 178 235 250

APEs 192 128 202 222

Source: Ladok

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InternationalisationworkatKIisconductedinaccordancewiththe”Actionplanfortheinternationalisationoffirst-cycleandsecond-cycleeducation,2010–2012”.

Thisyear,KIandthestudentunionshavecooperatedinordertoimprovethereceptionandservicesprovidedforincomingstudents.Thisworkisvitalforattractingforeignstudents,notleastthosesubjecttotuitionfees.Furthermore,KIhascollaborateswiththeUniversityofOviedoinSpainwithintheErasmusMundusprogramme;theoneyearMaster’sprogramme”PublicHealthinDisasters”comensesin2013.Thisprogrammeleadstoajointdegree.

Inaddition,theannualactivitieshavebeencarriedout,suchasinformationmeetingsregardingteacherandstudentexchange,socialactivitiesforincomingteachersandstudents,aswellascoursesinteachinginEnglish.ThescopeofKI’slong-standingcollaborationwithMakerereUniversityinUgandahasbeenfurtherexpandedin2012withtheadditionoftwomoreofKI’sstudyprogrammes.

KIisworkingtoincreaseteacherexchange.Thenumberofoutgoingteachershas,however,halvedduringtheyearduetothegovernmentexchangeprogramme”MobilityforTeachersandStudentswithinhighereducation,2011–2012”comingtoanend.Thenumberofoutgoingstudentshasalsodeclined,while

thenumberofincomingstudentsisrelativelyconsistent(seeTable8intheTablesappendixformoreinformation).ThedeclineinexchangewithintheframeworkoftheLinnaeus-Palmeprogrammehasdecreasedowingtoseveralprojectscomingtoanendandnewprojectsbeinginthedevelopmentphase.Onlyplanningtripsandteacherexchangetakeplaceduringthisdevelopmentphase.

Inadditiontothis,anumberofKIstudentseachyearcompletepartoftheirthesisworkabroadwithinexchangeprogrammes.In2012,anumberofmedicalstudentshavealsoconducteddatacollectionabroadfortheirthesis,howevernotwithintheframeworkofanexchangeprogramme.Studentswhoparticipateininternationalcoursessuchas”GlobalHealth”and”MedicaldevelopmentinEuropeandtheEU”alsocompletepartoftheireducationabroad.

Actionhastakentodevelopanewactionplanfortheinter-nationalisationoffirst-cycleandsecond-cycleprogrammesduringtheyear.ThegoaloftheplanisforKIgraduatestohavetheabilitytoworkbothinmulticulturalenvironmentsandinaninternationalmarketwithvaryingeconomicandsocialconditions.KIshouldalsobeanattractivestudydestinationforinternationalstudents.

Student exchange, 2012

Internationalisation

N O R T H A M E R I C A

S O U T H A M E R I C AA F R I C A

E U R O P E

A S I A

O C E A N I A

21 31

4 5

225 65

14 13

25 10

16 15

OUTGOING FROM KI

INCOMING TO KI

Source: Ladok

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FTE students, 2012Total 5,885

Single-subject courses 12%

Medicine 26%

Physiotherapy 6%

Nursing 10%

Psychology 4%

Dentistry 7%Occupational therapy 3%

Other beginners’ programmes 12%

Biomedical lab science 3%

Specialist nursing (cont.) 8%

Other continuation programmes 2%

Master’s programmes 7%

Full-time equivalent students (FTEs) and annual performance equivalents (APEs)In2012,thenumberofFTEstudentswas5,885andthenumberofAPEs5,307withintheframeworkofthefundingcap.Theresultisslightlylowerthanpreviouslyforecast.Theresultfor2012isSEK11.2millionoverthefundingcap,includingremunerationforAPEsfromDecember2011.

ThenumberofFTEstudentshasincreasedsomewhatincomparisonto2011,whilethenumberofAPEshasdecreased.Thisismainlyduetothefactthattherewere39courseweeksduring2012comparedtothenormal40andthat,asaresult,

moreexaminationswillberegisteredinthecalendaryear2013.Thecalculatedremunerationfortheyear’sactivitiesamountstoSEK598,958,000.TogetherwiththeperformancesfromDecem-ber2011ofSEK1,400,000thedirectgovernmentfundingfor2012willthusbeburdenedwithSEK600,358,000.Thisgivesanoutgoingappropriationssavingof49,785,000.

Eachprogramme’sshareofthetotalnumberofFTEstudentsisillustratedinthediagrambelow.ThenumberofFTEstudentsandAPEswithinthedifferentprogrammesisshowninTable6oftheTablesappendix.

Educational assignment

Source: Ladok

Remuneration for FTE students and APEs within the funding cap including December performances, 2009–2012, SEK thousands

2009 2010 2011 2012

Funding cap 552,204 619,449 616,148 589,150

Remuneration 532,674 553,772 587,977 600,358

Under/over funding cap -19,530 -65,677 -28,171 11,208

Including supplementary appropriations during the period 2009–2011

Sources: Ladok, public service agreement

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KIhadatotalof60fee-payingstudentsin2012.Withintheframeworkoftuitionfeeactivities,sevenMaster’sprogrammeshavebeenofferedinEnglishduringtheyear.

KIalsoofferedanumberofsingle-subjectcourses,alongwithcourseswithintheframeworkoftheEuroScholarsconsortiumandStockholmSummerSchool.ThelatterisacollaborationbetweenKI,KTHRoyalInstituteofTechnologyandStockholmUniversity.

ThirtyonenewstudentswereregisteredinKI’stwo-yearMaster’sprogrammesintheautumntermof2012.Inaddition,onestudentwasregisteredinthecomplementarytrainingfordentists.Ofthe32fee-payingstudents,12hadafullscholarshipwhile20studentspaidfees.Ofthetotalnumberofregisteredstudentsinterm1oftheMaster’sprogrammesinEnglish,thirdcountrystudentsrepresented15percentin2012.Thecorrespondingfigurefor2011was14percent.In2012,thenumberofFTEstudentswas33.6andthenumberofAPEswas27.7.

Internationalstudents’satisfactionwiththequalityofeducationandreceptionserviceshasincreasedsignificantly,asreflectedintheInternationalStudentBarometer2011/12.

TheinvestmentsmadebyKIwithinoperationsfinancedbytuitionfeesarealsointendedtobenefittheuniversity’sothereducationalactivities.KI’sassessmentisthatoperationsfinancedbytuitionfeesinvolveacertainamountofextraadministrativework.

Nonewstrategicagreementshavebeensignedwithuniver-sitiesoutsidetheEU/EEAareaasaresultoftheintroductionoftuitionfees.In2012,KIhad80thirdcountrystudentswithintheframeworkofexchangeagreements,comparedwith89studentsthepreviousyear.

LessthanSEK2.8millionofthecostsin2012representremunerationtothedepartmentsprovidingthecourses.Othercostsconsistofadministrationandmarketinginitiatives.

Tuition fees for students from a third country

Revenue and costs for operations financed by tuition fees (SEK thousand) 2011 2012Revenue 1,708 5,724Costs 3,645 5,895Total -1,937 -171

Source: Agresso

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TheSwedishNationalAgencyforHigherEducation’sevaluationshavebeeninfocusthroughout2012.TenofKI’sprogrammeshavebeenaudited.Twoprogrammesreceivedthegradeof”veryhighquality”,fivereceivedthegradeof”highquality”andtwoweregiventhegradeof”poorquality”.Inonecase,theSwedishNationalAgencyforHigherEducationhasnotyetreachedadecision.

AsseveralofKI’sprogrammesleadtobothgeneralqualifi-cationsandprofessionalqualifications,theself-evaluationprocesshasbeenextensive.Thisprocesshasconstitutedavitalpartoftheinternalqualitywork,asshortcomingsidentifiedthroughtheself-evaluationhavebeenimmediatelyaddressed.KIhasdevelopedactionplansforthoseprogrammesthatreceiveda”poorquality”grade,andtheassessmentisthatthelevelofqualitywillbedeemedsatisfactorywhentheSwedishNationalAgencyforHigherEducationperformsitsfollow-upevaluation.KIwillanalyseandtakeadvantageofthesuccessfactorsfoundintheprogrammesreceivinga”veryhighquality”grade.

Measures to improve the quality of educationInordertoensureandimprovethequalityofKI’sdegreeprojectwork,allsyllabifordegreeprojectswillbeaudited,alongwithalmostonehundredtheses.ThepreliminaryresultsoftheauditsrevealthatanumberofsyllabineedtoberevisedtoachieveahighercompliancewiththequalitativetargetsoftheHigherEducationOrdinance.Furthermore,itappearsthattheprocessofsystematicqualityassuranceofdegreeprojectsmustconti-nue.Itshouldbenotedthat,astheauditreveals,shortcomingsinthesyllabidonotnecessarilyresultinqualitydeficienciesintheprojects.Thereisanon-goingdialogueregardingthestepsthatneedtobetakenbasedontheresultsoftheaudits.

Duringtheyear,KIhasworkedtodefinewhatconstitutesexcellenceineducation.Thepurposeistoprovidetheeducationalorganisationwithtoolsforcontinuedstrategicqualitymanage-ment.

Atthestartoftheyear,KIimplementedanewcriterion-referencedcourseevaluationthatiscommontoallprogrammes.Thesurveyiscurrentlybeingevaluated.MeasurestoimprovethequalityofteachingactivitiesTherearecurrentlyseveralfunctionsatKIwiththetaskofsupportingtheprofessionaldevelopmentofteachersandsupervisorsanddevelopingtheteachingqualitywithintheprogrammes.Inordertooptimisethissupport,KIhasdecidedtoorganisationallycoordinatethesefunctionsstartingin2013.

Teacher training courses and professional development In2012,tendifferentcourseswereprovidedforKIteachersinteachingandlearninginhighereducation.

TheEducationalCongressin2012,thusfarorganisedannuallybyKI,focusedonthepossibilitiesofdevelopingstudentlearningwiththehelpofIT.Thereweremorethan300participantsintheCongress,mostlycomprisingteachers,studentsandclinicalsupervisorsfromKI.

KI’sTeachers’Daywasconductedwiththetheme”Sustainableeducation–choicesforthefuture”.TheTeachers’Dayfocusedonsustainabledevelopmentinabroadperspectivethatincludedaspectsofinternationalisation,equalopportunities,entrepreneur-shipandethics.

Funding for pedagogical projects and distinctionsEachyear,KIsetsasidefundsforpedagogicaldevelopmentprojectsthataimtodevelopandimprovethequalityoffirst-cycleandsecond-cycleeducation.Fundingwasgrantedtofivedifferentprojectsin2012.InadditiontotheKI-specificfunds,StockholmCountyCouncil(SCC)allocatesprojectfundingforpedagogicalresearchanddevelopmentprojectswithinStockholm’shealthsciencesprogrammes.

KIannuallypresentsawardstoteachers,teacherteams,oradministrativestaffwhohaveconductedsignificantworkwithpedagogicaldevelopmentorrenewalwithinfirst-cycleorsecond-cycleprogrammes.

Duringtheyear,threenewmemberswereappointedtobeincludedinthePedagogicalAcademy.Establishedin2011,theaimoftheAcademyistocreateanetworkforKIteachers.

Development of learning environments and student engagementThroughout2012,workcontinuedontheproject”FutureLearningEnvironments”,whichisacollaborationwithSCC.TheprojectaimstodevelopbothformalandinformallearningenvironmentsatKIandathospitals.Twoinformalenvironmentshavebeeninauguratedthisyear,oncampusinHuddingeandSolnarespectively,andsimilarprojectswillbecarriedoutattheKarolinskaUniversityHospitalinHuddinge,Södersjukhuset(StockholmSouthGeneralHospital)andDanderydHospital.Thestudentsseemtobenefitfromtheseenvironmentsandanevaluationoftheprojecthasbeeninitiated.

Thesuccessfulseminarseries”Getinspiredbyaprofessor”thatstartedin2011hascontinueditsrunduring2012.Inorderforasmanystudentsaspossibletotakepartinthelectures,theyarebeingpublishedonKI’swebsite.

Quality

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Gender distributionMostofKI’sfirst-cycleandsecond-cycleprogrammeshaveadistortedgenderratio,wheremenareintheminority.ItisonlytheStudyProgrammeinMedicinethathasarelativelyevengenderdistribution.Overall,thechangescomparedto2011areverysmall,butdifferencescanbenotedataprogrammelevel,forexample,theproportionofwomenamongbeginnersintheDentistryprogrammeincreasedbyabout12percentagepoints.Itisdifficulttoinfluencethegenderededucationalchoices.AsimilargenderdistributiontothatofKIcanbefoundatotheruniversitieswithhealthscienceprogrammes,aswellasinthelabourmarketthestudentsencounterfollowinggraduation.

KIinitiativesaimedatencouragingamoreevengenderdistributionamongthestudentsincludealwayshavingrepresentativesfrombothsexesinthemarketingcampaignstargetingprospectivestudents.KIhasalsoconductedaspecialprojectwithpurposeofprovidingin-depthknowledgeonwhyyoungmenarenotaslikelytoapplytoprogrammesinmedicineandhealthcare.Theresultshavebeenpublishedinthebook”Passingtheballandfittingin:Masculinity,footballandgender-relatededucationchoices”.TheseresultsmayalsobeusedbyKIinthecontextoffuturerecruitmentefforts.

The non-discrimination perspective in teachingDuring2012,thenon-discriminationperspectivehashadagreaterimpactinseveralofKI’sprogrammes.Thesubjectof

non-discriminationis,forexample,addressedincoursesdealingwithpatienttreatmentissuesandthefutureprofessionalroleofthestudents,butalsoincoursesdealingwithknowledgeareaswherealinkcanbemadebetweendifferentpatientgroupsandtheoccurrenceofdisease.Severalprogrammeshavealsointroducedissuesofdiscriminationintheircourseevaluationsurveys.

Furthermore,individualstudyprogrammeshaveconductedsurveysofstudentscomprisingtheunderrepresentedsex.Thesesurveysshowthattheyhaveaneedformalerolemodelsandthepossibilityofmeetinginasingle-sexenvironment.

Asincreasedknowledgeandawarenessamongsupervisorsandteachersisoneofthemostimportantconditionsforequalopportunitiesineducation,KIoffersitsteachersandclinicalsupervisorstrainingintheseissues.In2012,approximately130teachersandsupervisorsparticipatedinthistraining.KIalsoofferstrainingtothestudents,primarilywithregardtotheDiscriminationActandanon-discriminationperspectiveineducation.In2012,around165studentsparticipatedinthistraining.Inaddition,allnewstudentsareinformedaboutdiscriminationlegislationandaboutthesupportservicesavailableatKI.

Equal opportunities in teaching

Gender distribution of beginners on beginner’s programmes, 2012

Gender distribution of beginners on continuation programmes, 2012

0 % 20% 40% 60% 80% 100%

Occupational therapy

Audiology

Biomedicine

Biomedical lab science

Speech pathology & therapy

Medicine

Optometry

Psychology

Radiology nursing

Physiotherapy

Nursing

Dental hygiene

Dentistry

Total

Women

Men

0% 20% 40% 60% 80% 100%

Midwifery

Psychotherapy

Specialist nursing

Odontological prophylactis

Master’s 1 year

Master’s 2 year

Total

Women

Men

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Dental careInaccordancewiththepublicserviceagreement,KarolinskaInstitutetisrequiredtooperateadentalcarecentreinconnectionwithitsdentistryeducation.Thedentalcarecentreshouldcatertoboththeprogramme’sneedsandtheneedforclinicalodontologicalresearchanddevelopment.Thefacilityconsistsofbothpaediatricandadultdentalcare.Servicesavailableatthedentalcarecentreincludeeverythingfromadvicetoadvancedspecialistcare.Supportfunctionsareconnectedtotheactivities.During2012,thecentre’sactivitiesinvolvedapproximately36,500patientvisits.TheappropriationitemforthedentalcarecentrewasSEK92,640andthetotalcostwasSEK111,304.Asidefromthedesignatedgovernmentfunding,KIallocatesadditionalfundstotheseactivities.

Complementary training for doctors, nurses and dentists from third countriesTogetherwiththeuniversitiesofLund,GothenburgandLinköping,KIiscommissionedwithprovidingcomplementarytrainingforindividualsfromthirdcountrieswhohavecompletedadegreeinmedicine,dentistryornursing.KIcoordinatestheeducationalinitiatives.

Thecomplementarytrainingfordoctorsinvolvesoneyear’sfulltimestudies(60credits),ofwhich30creditsareearnedthroughplacements.Theprogrammebuildsonthestudents’previousknowledgeandexperience,andgreatemphasisisplacedonstudentsintegratingtheirknowledgeandskillsinaSwedishhealthcarecontext.

Thecombinedexperienceachievedthroughtheprogrammeisconsideredpositivefrombothastudentandcoursemanagementperspective.However,theavailabilityofhighqualityplacementsis,toacertainextent,stillaproblem.Thestudent’sknowledgeoftheSwedishlanguageiscrucialbothforthestudent’sabilitytofollowtheprogrammeandwhenitcomestodeepeningtheirprofessionalknowledge.

Thecomplementarytrainingfornursesinvolvesoneyear’sfulltimestudies(60credits).Theoreticalstudiesareinter-spersedwithworkbasedelements.During2012,thesyllabusfortheprogrammehasbeenrevisedinordertoclarifytheintendedlearningoutcome.Furthermore,medicalSwedishhasbeenintegratedintoallaspectsofthecourse,andthepartsof

theprogrammetakingplaceoncampushavebeengivenamoreclinicalfocus.

Aswithpreviousyears,KIhasfoundthatagoodknowledgeofSwedishisessentialforsuccessfullycompletingtheeducation.Thecomplementarytrainingfordentistsinvolvesoneyear’sfull-timestudies(60credits)andconsistsofboththeoryandclinicalskillstraining.

Experiencesfromthesecondroundofeducationsuggestthatstudents’theoreticalandclinicalknowledgevarytoasignificantextent,andthattheeducationmustbeadaptedtothestudents’abilities.Priorto2013,KIwillrevisethesyllabiinordertofacilitateadaptationtotheneedsofindividualstudents.Aswithpreviousexperience,ithasbeenfoundthatknowledgeoftheSwedishlanguagealsovaries.Apilotprojectisbeingconductedin2012and2013togetherwithSwedishforImmigrants(SFI)inSödertäljeMunicipalityinordertoenablestudentstoimprovetheirknowledgeofSwedish.

Utilisation of funds for complementary trainingRevenueperFTEstudentamountstoalmostSEK237,000forthecomplementarytrainingfordoctors,morethanSEK131,000fortheeducationfornursesandmorethanSEK302,000fortheeducationfordentists.Themannerinwhichtheseresourceshavebeenusedispresentedbelow.Intheitem”admissions”,onlyadmissionscostsatthedepartmentallevelareincluded(overallassessment).Otheradmissionscostsareincludedintheindirectcosts.Inorderforthedataregardingtheproportionoffundsbeingusedforteachingnottobemisleading,dataonplacementsshouldalsobeincluded.

KIcontinuouslymonitorsthestudentsundertakingcomplementarytraininginordertomakeindividualadjustments–insofarasitisfinanciallypossible.During2012,KIdevelopedasurveyquestionnairethat,in2013,willbedistributedtoallwhohaveparticipatedincomplementarytraining.Thepurposeofthisstudyismainlytoinvestigatetheextenttowhichthosewhocompletedtheeducationhavefoundworkasadoctor,dentistornurse.

Special undertakings

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Reporting of certain data

Qualified applicants Registered Non-completion Number of FTE students* Graduates

Complementary training for doctors

Spring term – 18 (20) 0 9.90 16

Autumn term 72 20 0 8.50 –

Complementary training for nurses

Spring term – 25 (26) 0 13.75 24

Autumn term 33 25 0 10.63

Complementary training for dentists

Spring term – 15 (16) 0 8.25 16

Autumn term 46 16 0 6.80 –

* Number of FTE students includes students subject to tuition fees.

() indicates the number of students registered for the autumn term 2011.

Sources: Ladok, NyA

Utilisation of funds for complementary training, 2012 (% of costs)

Doctors Nurses Dentists

Planning 4 4 3

Admissions 2 0 2

Validation 0 0 0

Teaching 30 46 13

Placement 39 21 36

Other, incl. indirect costs 25 29 46

Total 100 100 100

29

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Task of developing clinical education and researchKIhasreceivedSEK1,603(thousand)(2:72ap.9)forthedevelopmentofclinicaleducationandresearch.Theneedtodevelopclinicaleducationremainshigh,whichiswhyKIdecidedtousethefundsforactivitiesattheCentreforClinicalEducation(CCE).

CCE–whichisacollaborativebodybetweenKI,StockholmCountyCouncil(SCC)andtheindividualhighereductioninstitutionsinStockholm–hasanoverallandcoordinatingresponsibilityforplacementswithinStockholmCountyhealthandmedicalcare.

Activitiesarerunwithinfouroperationalareas:Inter-professionalEducation(IPE),pedagogicalinservicetrainingforteachers,pedagogicaldevelopmentandresearch,andqualityandlogisticsinworkintegratedlearning.

WithintheInterprofessionalEducation,variousseminarsandworkshopshavebeenconductedtoincreaseskillsandawarenesswithregardtointerprofessionallearning.Withinthe

frameworkofpedagogicalinservicetraining,bothmanagersandleaderswithinhealthcareandplacementsupervisorshavebeenofferedvariousformsofprofessionaldevelopment.

Withregardtopedagogicaldevelopmentandresearch,ateacher’sacademyhasbeencreated.Theacademyconstitutesacommonplatformforteachersandsupervisorswhereissuesofapedagogicalnaturecanbediscussed.Furthermore,KI–forexample,viaCCE–hasbeeninvolvedintheconstructionofacademicmedicalcentres,whoseaimistointegrateresearch,educationanddevelopmentinprimarycare.

In2012,effortscontinuedtodevelopanevaluationinstrumentforplacements.During2013,itisestimatedthattheinstrumentwillbeimplementedinsomeoftheCountyCouncil’sactivities.Inaddition,atrainingforstudentsfocusingonthekeepingofmedicalrecords,treatment,confidentialityandhygienehasbeendeveloped.Thisprogram-mewillbetested,afterwhichitwillbeenterintooperationin2013.

Other

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TherevenueandcostdevelopmentforBachelor’s(first-cycle)andMaster’s(second-cycle)educationispresentedinthetablebelow.Therevenuefromgovernmentfundingispresentedincludingfundingformedicaltrainingandresearch.Furtherinformationcanbefoundunderthefinancialreport.

Unallocated revenue and costsProfitfromsharesinsubsidiariesandassociatedcompanies,aswellastaxcollection,isnotdistributedwithinlinesofbusiness.SeetherevenuestatementinthesectionFinancialreport.

Financial report

Total for first- and second-cycle education, SEK millions

2009 2010 2011 2012

Revenue

Direct government funding 759.2 754.0 805.5 833.1

Fees and other remuneration 84.9 83.9 100.0 100.6

Grants 8.8 12.7 20.6 19.8

Financial 0.0 0.1 0.1 0.0

Total revenue 852.9 850.7 926.2 953.6

Costs

Staff 420.3 434.0 488.2 507.7

Premises 100.5 99.6 99.0 109.2

Other operations 304.4 295.1 318.1 335.7

Financial 0.2 0.2 0.3 0.1

Depreciation 23.6 23.3 17.9 12.2

Total costs 849.0 852.1 923.5 965.0

Transfers

Government funding 4.2 4.3 7.3 7.6

Funding from other government agencies 1.9 0.0 0.0 0.0

Contributions paid -6.1 -4.3 -7.3 -7.6

Change in capital for the year

Annum 3.9 -1.4 2.6 -11.4

Balanced (IB) 134.1 137.9 136.5 139.1

Total (UB) 137.9 136.5 139.1 127.8

Source: Agresso

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Research and doctoral(third-cycle) education

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28 Karolinska Institutet Annual Report 2012

New research findings – some examplesAsamedicaluniversity,KIconductsresearchwithinabroadspectrumofsubjectscoveringalltypesofdiseases.Theresearchiscarriedoutatalllevels,frompurelyexperimentallaboratoryresearchonthemappingofdiseaseemergenceanddevelopment,tomorepatientrelatedtreatmentresearchandclinicaltrials.Hereisaselectionofnewfindingsthathavebeenpublishedinhighlyrankedscientificjournalsoverthepastyear.

Breast cancerSeveralresearchreportsonbreastcancerhavebeenpresentedduringtheyear,whichisnowthemostcommonformofcancerinwomen.Breastcancerisclassifiedaccordingtosurfacemarkersexhibitedbycancercells,whichisofcrucialimportancewithregardtochoiceoftreatment.Ithasnowbeenproventhatthesemarkerschangeduringthecourseofapatient’sdisease(JournalofClinicalOncology,June).Clinicalobservationsandageneticmutationrelevanttothediseaseprognosishavealsobeenpresented(JournalofClinicalOncology,AugustandOctober).

Twomajorclinicaltrials(Phase3)revealedthattreatmentofbreastcancerwithtwodrugsincombinationwasnomoreeffectivethantreatmentwithasingledrug(JournalofClinicalOncology,February).Nowadays,anincreasingnumberofwomensurvivefollowingbreastcancertreatment,andonestudyhasshownthatthevastmajorityreturntotheirpreviousemploymentandcontinueworkingtothesameextentasbeforethediagnosis(JournalofClinicalOncology,July).

Cancer drugsThesmallcellmoleculep53,whichprotectsagainsttumourdevelopmentandwhichismutatedinabouthalfofallcancercells,isanattractivetargetforcancermedications.Aninitialhumantrialinvolvingasubstancethatrecreatesamutatedp53hasrevealedpromisingresults(JournalofClinicalOncology,September).Severalstudieshaverevealedfactorsatthecellular,molecularandgeneticlevelthatprovideagreaterunderstandingofhowcancercellsfunctionand,thus,howtheycanbetackled(Science,November,JournalofExperimentalMedicine,February,NatureBiotechnology,FebruaryandJuly).

Quality of lifeAmajorityofthepatientswhohaveundergonesurgeryfortrachealcancerwerefound,duringafollowupafterfiveyears,toconsiderthemselveshavingahighqualityoflife.Asmallgroup,however,hadpersistentandincreasingdiscomfortfromthesurgery(JournalofClinicalOncology,JanuaryandApril).Thefactthatpeoplediagnosedwithcancerrunasignificantlyhigherriskofsuicideordeathfromcardiovasculardiseasedirectlyafterreceivingtheirdiagnosishasprovidednewknow-ledgeconsideredimportantforbothrelativesandhealthcareprofessionals(NewEnglandJournalofMedicine,April).Astudyhasshownthatwomenwhoareabouttoundergo

cancertreatmentreceivesignificantlylessinformationonhowthetreatmentwillaffecttheirfutureabilitytohavechildren,whencomparedtomeninthesamesituation(JournalofClinicalOncology,May).Theimportanceofpalliative,non-pharmacologicalcareinthefinalstageoflifehasbeendescribedintheformofbodycare,touch,asafeenvironmentandritualssurroundingdeath.(PLOSMedicine,February).

Blood diseaseApreliminaryreviewofallSwedishpatientswithchronicblooddiseases,ormyeloproliferativediseases,revealedthattheprognosisforsurvivalhasimprovedsomewhatinrecentdecades(JournalofClinicalOncology,July).

Rheumatoid arthritisAnewdrugforrheumatoidarthritis(RA)hasprovenaseffectiveasbiologicaldrugsbut,unlikethese,thenewpreparationcanbetakenintabletform(NewEnglandJournalofMedicine,August).Inanotherstudy,abiologicaldrugwasrevealedtobeeffectivewhentakenintandemwithconventionalmedication,atleastduringthefirsttwoyearsoftreatment(Lancet,May).OnestudyhasalsochangedtheevaluationofbloodclotriskinRA.Theriskwascertainlyelevatedbutwasnotrelatedtohospitalisation,somethingwhichwaspreviouslyassumed(JournaloftheAmericanMedicalAssociation,October).

Heart failureHeartfailureisoneofthemostcommoncausesofhospitalisationanddeath,andoccursinvariousforms.Ananalysisofdatafromthenationalheartfailureregistrysuggeststhatcommonlyprescribeddrugsforheartfailureandhighbloodpressurecanhaveawiderrangeofapplicationsthanpreviouslyknownandcanalsobeemployedagainst’HFPEF’,atypeofheartfailurewhichhad,todate,lackedanestablishedtreatmentplan(JournaloftheAmericanMedicalAssociation,November).Recentresultsalsosuggestthattreatmentwithaso-called’biventricularpacemaker’couldbeofvalue,evenforpatientswithamildercaseofheartfailure(EuropeanHeartJournal,October).

Blood vesselsThemappingofthearginaseenzyme,whichcounteractstheformationofprotectivenitricoxideinthebloodvessels,hasledtoacompletelynewexplanatorymodelforhowvascularcomplicationspresentindiabeticpatients(Circulation,November).

Physical activityFurtherimportancehasbeenattributedtophysicalactivitywhenitwasrevealedthatmuscularweaknessinyouthisassociatedwiththeincreasedriskofprematuredeath,mainlyduetosuicideorcardiovasculardisease(BritishMedicalJournal,November).Researchhasshownthatexerciseprovides

Research

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Karolinska Institutet Annual Report 2012 29

so-calledepigeneticchangesintheDNAofmusclecells,whichaffectstheirabilitytorespondtodifferentsignalsfromthebody(CellMetabolism,March).

ObesityAlookbackatindividualswhohaveundergonegastricbypasssurgeryrevealedthattheycontinuedtoutilisehealthservicestothesameextentaspeoplewhoreceivedconventionalobesitytreatment,despitethefactthatsurgeryoftenresultedinsustainedweightlossandthereforeareducedriskofdiseasessuchasdiabetes,coronarythrombosis,strokeandcancer(JournaloftheAmericanMedicalAssociation,September).

DiabetesAcompletelynewwaytotreatdiabeteshasbeentestedonmice.Themethodistoblockasignalpathandthuspreventfatbeingstoredinthe”wrong”placesinthebody,suchasthemusclesandheart(Nature,September).KIresearchershaveparticipatedinseveralinternationalresearchconsortiawhichhaveidentifieddifferentgeneticvariantsthataffecthowtype2diabetesdevelops(NatureGenetics,MayandAugust).

InfectionsAnanalysisofseveralinternationalstudiesofthethreeinfec-tiousdiseasesHIV,tuberculosisandhepatitisCamonghome-lessgroupsshowedthattheoccurrenceofthediseasesamongthesegroupswassignificantlyhigherthanamongthegeneralpopulation.However,theprevalenceofthesediseaseswasunevenlydistributedbetweengroupsandcountries(Lancet,August).Ithasalsobeenshownthattheincidenceofcondy-loma,genitalwarts,hasfallensharplyinyoungwomeninSwe-den,whichislikelyduetothecurrentlyavailableHPV(Humanpapillomavirus)vaccine(JournalofInfectiousDiseases,July).

Mitochondrial DNAMutationsinthegeneticmaterialofthecell’smitochondriacancauseavarietyofseriousillnessessuchasmuscularweakness,neurodegenerativediseases,cardiovasculardiseaseanddiabetes.Ithasnowbeenshownthattheriskofachildinheritingamito-chondrialdiseaseisalreadydeterminedwhenthefuturemotherisanembryo(NatureGenetics,October).

Brain cellsTheregenerationofneuronsinvariouspartsofthebrainhasbeenstudiedintensivelyinrecentyears.Ithasnowbeenshownthattheareaofthebrainneededtointerpretodourrecognitiondiffersbetweenhumansandothermammals,wherebynonewneuronsareformedthereinhumansafterbirth.Thiscouldexplainwhythehumansenseofsmellisnormallysomuchworsethanthatofananimal(Neuron,May).Awholenewgroupofneuronsinthebrainthataresignificantwithregardto,forexample,heartrateandbloodpressure,havebeendescribed(JournalofClinicalInvestigation,December).Twomolecules

havebeenidentifiedwhichareimportantforthesurvivalandregenerationofneuronsinthebrain,includingdopamine-producingneurons.ThisisadiscoverythatcouldultimatelyhaveimplicationsfortreatingdiseasessuchasParkinson’sdisease(NatureChemicalBiology,December).

Alzheimer’s diseaseAninitialclinicaltrialofapotentialvaccineforAlzheimer’sdiseaseshowedthatthevaccinewaswellreceivedbythebodyandthatanimmuneresponsedevelopedagainsttheharmfulpeptidebetaamyloid(Lancet,June).Inanotherstudy,researchshowedthatevenminorformsofamyloidarelikelytohavesignificanceforthedevelopmentofAlzheimer’sdisease,andthatthesecouldbeapotentialtargetforfuturedrugs(Neurology,June).

Mental illnessDuringdepression,thebrain’sabilitytochangeisreducedanditbecomeslessadaptablewithregardtoissuessuchasmemorystorage.Researchhasnowshownthatthisisduetotheimpairedfunctionofthebrain’ssupportcells,knowledgethatcanpavethewayfornewmethodsoftreatingdepression(MolecularPsychiatry,February).

Aclearcorrelationhasbeendiscoveredbetweenprematurebirthandanincreasedriskofmentalillnesslaterinlife,suchasbipolardisorder,psychosisanddepression.Thiscanprobablybeexplainedbyabnormalitiesinbraindevelopmentwherethenervoussystemofpretermbirthsisimmatureandextremelysensitive(ArchivesofGeneralPsychiatry,June).Potentialriskshavebeenhighlightedforcasesbothwithandwithoutdrugtreatmentduringpregnancyforwomenwithbipolardisorder.Theanalysisrevealedadifficultbalancebetweentherisksofdeepdepressionresultingfromanuntreatedillness,andtherisksofbirthdefectsorothercomplicationsresultingfromthedrugtreatment(BritishMedicalJournal,November).

AdrugcurrentlybeingtestedagainstHuntington’sdiseasehasbeenshowntoalsointeractwithareceptorrelevanttoschizophrenia,Parkinson’sdiseaseandcertainneuro-degenerativeconditions,anditwouldthereforebeofinterestforthedevelopmentoftreatmentsagainstthesediseases(MolecularPsychiatry,February).

ADHDAcomprehensiveregistrystudyhasshownthatcriminalactivityinadultswithADHD(Attention-Deficit/HyperactivityDisorder)fellsharplyduringperiodswhentheywereonmedicationfortheconditioncomparedtowhentheywerenotmedicated(NewEnglandJournalofMedicine,November).PreviousresearchhasshownthatpeoplewithADHDrunahigherriskofbecominginvolvedincriminality.

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30 Karolinska Institutet Annual Report 2012

1,00

1,25

1,50

1,75

Measuring scientific production – bibliometrics KIusesbibliometricstomeasurethespreadandimpactofitsresearchfindings.Bibliometricsinvolvestheapplicationofmathematicalandstatisticalprocedurestoarticles,booksandothermedia.Reporteddataisanalysedoveralongperiodoftime.Thenumberofarticlesisaroughmeasureofscientificproductionanddependsonavarietyoffactors,suchasthepublicationpatternswithindifferentdisciplines.ThebarsofthefigurebelowtotherightrepresentpublicationswithsomekindofaddressthatcanbelinkedtoKI.Figuresforthenumber

ofpublicationsarebasedonyearofpublication,butsincethedatabaseisupdatedwithaslighttimelag,therearenocompletestatisticsforthepastyearatthetimeofpublishingthisannualreport.Figuresfor2012willthereforenotbegiveninthecharttoavoidanydistortionofthefacts.Amoreaccurateassessmentofscientificproductionispossiblebymakingcomparisonsoveralongerperiodoftime.KIhasthereforedecidedtodrawcomparisonsforthe2002–2011period,duringwhichthetotalproductionofpublicationsincreasedby38percent.

2012 Publications

0

1000

2000

3000

4000

5000

6000

2002 2003 2004 2005 2006 2007 2008 2009 2010 2011

Other

Letter

Editorial material

Meeting abstract

Review

Article

2002 2003 2004 2005 2006 2007 2008 2009 2010 2011

Karolinska Institutet

Global average

2012 Field normalised citation score

Quality in research

The”Fieldnormalisedcitationscore”comparesthecitationrateofaparticulararticlewithpublicationsofthesameclass(i.e.thesamekindofdocumentfromthesameyearandwithinthesamesubject).Anindividualarticle’sindicatoris1ifitiscitedasmanytimesasthemeancitationrateforsimilararticles.ThediagramabovegivesthemeanfieldnormalisedcitationscoreforallarticlesfromKIperyear.Between2006and2011,KI’sscoreclimbedfrom1.46to1.55.KIthushasarelativelystablecitationrateandisclearlymaintainingitsglobalposition.Publicationsfrom2012havenotyetbeencitedtotheextentrequiredtoprovidestableandreliabledataandhavethereforebeenomittedfromtheabovediagram.

External research assessment (ERA)TheextensiveexternalevaluationofKI’sresearchwhichwascompletedin2011hasbeenfollowedupthroughdepartmentvisitsbytheDeanofResearch.Thisfollow-upfocusedonthemanagementofresearchgroupsthathadgarnishedpoorresultsintheevaluation.AnimportantissueintheERAevaluationwasthedefinitionofgroupleadersandtheirroleandresponsibility.

Thereisanobviousneedforaclearerand,withinKI,amorecoherentdefinitioninthisrespect.

Thematic Translational CentresTheeighttranslationalcentresatKIhavebeenevaluatedduringtheyear.Theevaluationrevealsthatmostcentres,inanimpressiveandefficientmanner,havecreatednewpartnerships,venues,recruitmentandjointprojects,severalofwhichwouldhardlyhaveexistedwithoutthiseffort.Severalprojectswillhaveaclearimpactinhealthcare.Theevaluationteambelievesthatitisimportantthatthisinitiativecontinues.Onecentrereceivedreducedsupportpendinganadditionalfollow-up,whileanothercentrewasnotgrantedcontinuedsupport.

Identification and recruitment of new researchersThroughtheutilisationof,forexample,selectionprocedure,threeprominentresearchersinthefieldofregenerativemedicinehavebeenrecruitedtothepositionofprofessoratKI.Animportantroleinthisworkisthenewlyformedstrategicrecruitmentgroup.Thegroup’sworkwillbebasedonKI’slong-

Source: Web of Science

Source: Web of Science

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Karolinska Institutet Annual Report 2012 31

Other

Letter

Editorial material

Meeting abstract

Review

Article

termstrategy,theERA2010evaluationandKI’sstaffinventory.Duringtheyear,thegroupconductedacompetenceinventoryanddraftedproposalsfortheintroductionofanewacademicappointmentasSeniorResearchSpecialist.

Thepossibilityofa”trainingposition”wasalsointroducedintotheHigherEducationOrdinancethisyear.Againstthisbackground,KIannouncedfundingfor20ResearchAssociatepositionsintheautumn.Fundshavealsobeenallocatedfor20positionsforyoungresearchers(”researchassociateextension”).

Research basisResearchbasisimpliesthateventhoseteacherswhosemaintaskisteachingmusthavethemeans–financiallyandtime-wise–toconducttheirownresearchandthusincreasetheconnectionbetweenteachingandcurrentresearch.

Inlightofthis,announcementshavebeenmadeofuptotwelveseniorlectureshipswithparticularfocusonteaching.

Research documentationThedevelopmentofresearchdocumentationfocusesonanimprovedsolutionforthestorageofresearchdata,includingrawdata,aswellasefficientandcompletetrackability.

AnimportantelementofthisworkistheintroductionofElectronicLaboratoryNotebooks(ELN).Attheendoftheyear,thereweremorethan1,500ELNusers.

Organisation of laboratory animal activitiesAfunctional,clearandcentrallyestablishedorganisationforanimalexperimentationisacriticalqualityissueasregardsprovidingsafeandsecureconditionsforresearch.InviewoftheEUDirectiveontheprotectionofanimals,adecisionhasbeenreachedtoestablishalocalanimalwelfarebody.OperationalactivitieswithinKIarecollectedunderaninternalorganisationalunitforcomparativemedicine.Thisunitisinchargeofallaspectsofanimalexperimentationandprovidesresearchers,doctoralstudentsandotherstaffwithservicesandguidance.

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32 Karolinska Institutet Annual Report 2012

*Scholarships are not included for 2011-2012. Direct comparisons cannot be made with 2009-2010, where scholarships have been included.

Source: Agresso

Development research funds

1,000

1,500

2,000

2,500

3,000

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

External

Government

Research funding

ThepositivedevelopmentofresearchfundingatKIcontinues.Thisappliestobothdirectgovernmentfundingandexternalfunds.Fundingfromresearchcouncilshasincreasedby50percentsince2009.Duringthisperiod,directgovernmentfundinghasalsoincreasedby30percent,therebyconstitutingalargerincreasethanthatofexternalfundsforthisperiod(7percent).

Theforeignfinanciers,however,havenotkeptpacewiththisdevelopment,havinginsteaddecreasedfundingbyapproximately11percent.ThesefiguresshowthatSweden’srelativelypositiveeconomicdevelopmentinrecentyearshasalsogivenbothpublicandprivatefinanciersopportunitiesforinvestmentwithinresearch.

Total revenue for research, 2009–2012, SEK millions

FINANCIERS 2009 2010 2011 2012Change

2011–2012

Foundations and organisations 645 654 688 692 0.6%

Foreign funding (see below) 467 496 431 416 -3.5%

Research councils 484 597 654 730 11.5%

Municipalities and county councils 559 551 427 475 3.9%

Other Government funding 304 260 298 349 17.0%

Swedish business sector 196 196 171 168 -1.5%

KI funds 57 53 67 56 -16.1%

Financial revenue 18 17 56 50 -11.0%

Total external funding 2,731 2,824 2,792 2,935 4.0%

Direct government funding 1,326 1,581 1,630 1,732 6.3%

Total 4,057 4,405 4,422 4,667 4.8%

Proportion of external funding 67% 64% 63% 63%

Total revenue from foreign funding, 2009–2012, SEK millions

EU * 234 231 224 194 -13.6%

Foundations and organisations 134 195 128 150 16.9%

Business sector 100 69 79 73 -7.7%

Total 467 496 431 416 -3.5%

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Karolinska Institutet Annual Report 2012 33

European UnionKIretaineditspositionasthelargestrecipientofEUfundsofallSwedishuniversities,andasoneofthelargestinEuropeinthecategoryof”health”.ThetotalnumberofEU-fundedprojectsatKIhasincreasedcomparedtopreviousyears.However,researchgrantshavefallenby15percentsincethebudgetaryyear2011andamountedtoSEK200millionin2012.

Thisamountincludesscholarshipsforboth2011and2012.ApproximatelyonequarterofthedecreaseiscausedbychangesintheexchangerateintheformofastrongerSwedishKronaagainsttheEuro.AnotherreasonisthatalargenumberofcooperationprojectscoordinatedbyKIexpiredin2012,whilethenewlyaddedprojectsgenerallyhadamoremodestbudget.Anexception,however,istherevenuefromtheEuropeanResearchCouncilreceivedbyindividualresearchers,whichincreasedsignificantlyin2012.ThetrendisthereforethatKIisstrengtheningitspositionwithrespecttotheamountofindividualexcellentresearchers(inso-called”bottom-up”projectswheretheresearchtopiciscontrolledbytheresearchersthemselves),butisreducingitsparticipationinexcellentresearchconstellations(so-called”top-down”projectswhereresearchtopicsaredefinedbytheEU).

European support for individual researchersEuropeangrantsforindividualresearchersareprimarilyreceivedfromtheEuropeanResearchCouncil(ERC)andtheResearchExecutiveAgency(REA).TheERCisoneofthefourpartsoftheSeventhFrameworkProgramme(FP7).Grantsareawardedtoindividualresearchers/researchgroupswhereonly”excellence”isconsideredaselectioncriterion.KIhastencurrentERCAdvancedGrantsandtwelveStartingGrants.In2012,revenuefromERCresearchgrantsamountedtoSEK51million,whichcorrespondstoanincreaseof26percentcomparedto2011.TheREAadministersanotherpillarwithintheFP7,alsocalledthePeopleProgrammeortheMarieCurieProgramme,whichaimstostrengthenindividualresearchersintheircareerdevelopmentbybroadeningexcellentresearchwithinbothindustryandacademia.In2012,thenumberofMarieCurieFellowshipsatKIincreasedfrom29to37.

InvolvementwithintheFP6wasconcludedthroughthefinalreportingoftwoprojectsin2012.KIhasparticipatedin234FP7projectsin2012.KIhasalsoactedascoordinatorfor21oftheseprojects.

Revenue from the EU (including scholarships)

0

50

100

150

200

250

2004 2005 2006 2007 2008 2009 2010 2011 2012

113,4

138,8

172,5

185,7

214,2

235,2 232,9225,6

193,7

EU

Scholarships

10,5

7,1

Source: Agresso

Number of EU projects, 2008–2012

2008 2009 2010 2011 2012

Total number of projects 260 230 204 222 234

– of which KI is coordinator 41 38 29 31 21

Source: EU database KI

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34 Karolinska Institutet Annual Report 2012

American research grantsKIisoneofthemainrecipientsofAmericanresearchgrantsinEurope.ResearchrevenuefromAmericanfinanciersamountedtoSEK58millionin2012,ofwhichSEK19.6millionwasfromtheNationalInstitutesofHealth(NIH),KI’smostimportantpartneroutsideEurope.SEK32.8millionfromAmericannon-profitorganisationsandprivatefoundationsisalsoincludedinthetotalfigure.

AsidefromNIHfunding,2012sawKIreceivefederalfundsfromtheAgencyforHealthcareResearchandQuality,theEmployeeBenefitsSecurityAdministration,theUSArmyandtheNationalScienceFoundationforatotalof38researchprojects,10ofwhichwerecoordinatedbyKI.

Funds for strategic research fieldsKIhasestablishednationalresearchinitiativeswithinsixstrategicresearchfields(SRFs,inSwedish:SFO):diabetes,neuroscience,healthcarescience,cancer,epidemiologyandstemcells/regenerativemedicine.EachSRFseekstodevelopeffectiveresearchenvironmentswithintherespectivefieldsandincreasemobilitybetweenpreclinicalandclinicalresearchandindustry.

ThestrategicresearchfundsamountedtoSEK136,420,000SEK(12,198,000)ofwhichhasbeenpaidtoco-applicantuniversities.ThedistributioninvolvesSEK4,222,000fromSRFdiabetestoUmeåUniversity,SEK2,817,000fromSRFneuro-sciencetoUmeåUniversityandSEK1,127,000toKTH,aswellasSEK4,032,000fromSRFHealthcareSciencetoUmeåUniversity.

Throughouttheyear,SEK119,998,000hasbeenexpendedwithinthesixstrategicresearchfieldsunderKI’sresponsibility,whichimpactsthechangeincapitalfortheyearpositivelyintheamountofSEK16,422,000.AmoredetailedfinancialreportissubmittedannuallytotheSwedishResearchCouncil.

ThedevelopmentoftheSRFenvironmentsandsynergieswithotherstrategicinitiativesprovideKIwithastrongbase

forcreatinginternationallypioneeringresearchprofileswithinrespectivefields.

KIparticipatesintwoadditionalSRFventureswithinmolecularbioscience(ScienceforLifeLaboratory)andwithinE-science.SciLifeLabrepresentsapoolingofresourcesfromKI,KTH,StockholmUniversityandUppsalaUniversity.TheestablishmentofSciLifeLabhasprovidedresearchersatKIwithuniqueopportunitiestoconducttechnicallychallenginglarge-scaleresearchprojectsfocusingonthestudyofgenesandprote-ins.SciLife-LabenablesresearchersatKIandtherestofSwedentohaveaccesstothemoderntechnologiesandtoolscreatedasaresultoftoday’srapidtechnologicaldevelopment.SciLifeLabworkstowardscreatingnaturalcollaborativeplatformswithseveralnationalinfrastructures,exemplifiedbyCBCS,BBMRI.seandSWEDSTRUCT(seebelowunderFundsforstrategicinfrastructure).

Funds for strategic infrastructureIn2012,KIwastaskedbytheSwedishResearchCouncil(SRC,inSwedish:VR)toestablishanationalinfrastructureinstructuralbiology,SWEDSTRUCT,financedbytheSRCandwithstrategicresourcesfromKI.TheinfrastructureisbasedonacollaborationofexistingresearchenvironmentsinStockholm,GothenburgandLund(MAXIV).Previously,KIhascoordinatedtwoadditionalnationalinfrastructures.Withinthefieldofchemicalbiology,ChemicalBiologyConsortiumSweden(CBCS)hasbeentaskedwithofferingresearcherslarge-scalebindingstudiesofchemicalmoleculestovarioustargetproteins.BiobankingandMolecularResourceInfrastructureofSweden(BBMRI.se)aimstocreateanationalstandardforthecollectionofbiobanksamples,alongwithcosteffectiveopportunitiesforlong-termstorageandsampleanalysis.

BBMRI.seissupportedbyallmedicaluniversitiesinSwedenanddifferentunitswillbeestablishedatvariouslocationsinthecountry.Eachoperationisledbyaboardofdirectors.

International Neuroinformatics Coordinating Facility (INCF)

Neuroinformaticsisaseparatepartofbioinformaticswhichhasgreatsignificanceforthedevelopmentofknowledgeonnervoussystemfunctionsanddiseaseswithinthepsychiatricandneuro-logicalfield.

INCFhas17membercountriesinEurope,NorthAmerica,AustraliaandAsia,andisfinancedthroughfeesrelatedtothecountries’investmentsinresearchanddevelopment(rollingcapitalfor2012isSEK17.8million).TheSecretariathas14employees,primarilyresearcherswithdoctoraldegrees.KIplacespremisesandadministrativeserviceatINCF’sdisposal.

During2012,INCFhasworkedthroughthefollowingpro-grammeareas:DigitalBrainAtlasing;OntologiesforNeural

Structures;Multi-scalemodeling;andStandardsforDatasharing.Morethan150leadinginternationalresearchers,mainlyfromthemembercountries,areinvolvedintheprogrammes.INCFisworkingcloselywiththeNIHandtheEUtodevelopneuro-informaticswithinamultinationalprogrammefortheanalysisoftraumaticbraininjuries.In2012,INCFalsodevelopedthesoftware”INCFDataspace”,whichcanbeinstalledonanycomputerorserver.Inthisway,neuroscientificdatacaneasilybemadeaccessibleandsearchableforallwhoareconnectedtoDataspace.Dataspaceisapartoftheinternationalcyber-infrastructureforneuroinformatics,whichisoneofINCF’sprimarymandates.

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Karolinska Institutet Annual Report 2012 35

Doctoral education

ThenumberofactivedoctoralstudentsatKIhasincreasedby6.7percentsince2009.KI’sturnoverforresearchduringthesameperiodincreasedby15percent,whilethenumberofdegreesawardeddecreasedby8.4percent.Thisimpliesacontinuedhighnumberofdoctoralstudentswhich,however,hasnotincreasedatthesamerateastheturnover.Thenumberoflicentiatedegreesisstilllow.KIcontinuestoanalysewhethertherelationshipbetweenthevolumeofdoctoralstudentsand

careeropportunitiesfollowinggraduationneedstobechanged.Aclearandcompetitivecareerpathisanessentialtoolinrealisingthepotentialofthebestyoungresearchers.Thegenderdistributionamongbothactivedoctoralstudentsandgraduatesisapproximately60percentwomenand40percentmen.Thisproportionhasremainedlargelyunchangedduringtheperiod2009to2012.AlsoseeTable10intheTablesappendix.

Active doctoral students at KI

0

500

1,000

1,500

2,000

2,500

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Theses defended at KI

0

50

100

150

200

250

300

350

400

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Total

Women

Men

Source: LADOK

Doctoral education: admissions, registered students and degrees awarded

2008 2009 2010 2011 2012

Doctoral admissions 420 420 450 409 438

– of which are licentiates 12 19 18 12 15

Registered doctoral students (active _>10%) 2,080 2,028 2,076 2,133 2,165

Licentiate degrees 15 17 21 14 14

PhD degrees 352 392 367 349 359

- of which with previous have a licentiate 18 20 12 12 3

Source: LADOK

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36 Karolinska Institutet Annual Report 2012

Actual period of studyTheactualperiodofstudyhasstabilisedatanormallevelfouryearsafteraslowincreasesince2006.Thereasonsforthestabilisationarebetterregistrationproceduresandmonitoring.

Actual period of study, doctoral education

0

1

2

3

4

5

Doctor of Philosophy

Licentiate

2006 2007 2008 2009 2010 2011 2012

Source: LADOK

Student financeTheproportionofdoctoralgrantsinrelationtodoctoralstudentshipsremainsunchangedataround78percent.Theproportionofexternalfundinghasdecreasedsince2009

from72to65percent.Thisismainlyduetothepositivedevelopmentofdirectgovernmentfundingoverthisperiod,whichhasenabledincreasedstatefunding.

Source: Agresso and Primula

Costs of doctoral educationTheaveragecostofadoctoralstudentwithemployment/doctoralgrantsworksoutatanestimatedSEK1,190,000for2011(seetotheright),anincreaseof2.5percentcomparedwiththepreviousyear.Itmaybenotedthatthecostofsalaries/doctoralgrantsdecreasedbetweenyears.Thisisnotduetoanactualreductionofthesalaries/grants,butduetothefactthat,relativelyspeaking,thenumberofdoctoralgrantsincreasedmorethanthenumberofdoctoralstudentships.

Thedataisbasedinpartonassumptions,whichiswhythecostshouldbeviewedasapproximate.Seeappendix:Costsforperformance

Source: Agresso and Primula

Costs per performance in doctoral education, SEK thousand 2011 2012

Supervision costs Salaries 151 153Operating costs 46 50Premises 25 28Depreciation 8 9Subtotal 230 240

Doctoral student costs Salaries/doctoral grants 341 327Operating costs 237 256Premises 130 143Depreciation 42 46Subtotal 750 772

Indirect costs – from salaries and operations 181 178

Total costs 1,161 1,190

Student finance, 2009–2012

2009 2010 2011 2012

Student finance by discipline SEK % SEK % SEK % SEK %

Doctoral studentship 219,711 78 227,127 78 235,539 78 241,299 77

Doctoral grant 63,203 22 63,639 22 66,218 22 70,061 23

of which is direct Government funding

79,568 28 93,715 32 108,300 36 109,646 35

of which is external funding

203,346 72 197,051 68 193,457 64 201,714 65

Total 282,914 290,766 301,757 311,360

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Karolinska Institutet Annual Report 2012 37

Quality in doctoral education

Recruitment of doctoral studentsOnegoalisthatthemainproportionofdoctoralstudentsatKIwillberecruitedincompetition.Acompetitiverecruitmentprocessisexpectedtobroadentherecruitmentbaseofdoctoralstudentsandtoimprovethematchingofdoctoralstudentandtraininglocation.Throughouttheyear,over130doctoralpositionshavebeenadvertisedviaKI’srecruitmentsystem,whichismorethandoublethatofthepreviousyear.

Plagiarism checks within doctoral educationDuringtheyear,workhascommencedtointroduceplagiarismcheckswithindoctoraleducation.Plagiarismchecksareemployedroutinelynowadayswithinalllevelsofeducation.Sincethespringtermof2012,allcourseprovidersatthedocto-rallevelhavehadaccesstotheanti-plagiarismtoolUrkund,andareexpectedtouseitforhomeassignmentswhereplagiarismcanoccur.

TheintentionisalsothatbackgroundmaterialinKI’sdoctoralthesesisscrutinized.Apilotstudywasconductedintheautumn,whereissuessuchasreliabilityofthevariousanti-plagiarismtoolsweretested.Theimpetusbehindthesemeasuresisprimarilytoincreasedoctoralstudents’incentivestowriteoriginalandthoroughtextsratherthantodetectpotentialcheating.

Monitoringofthedoctoralstudents’viewsontheeducationExitPollisasurveywhichissentouttoalldoctoralgraduatesandlicentiates.Resultsfromfouryearshavebeencompiled,2008–2011.Theresultsshowthat87percentofthedoctoralstudentsarefullyorpartiallysatisfiedwiththeirtimeasdoctoralstudentsatKI,andthat89percentwouldrecommendKItoprospectivedoctoralstudents.Giventhechoice,85percentwouldchoosetoundergothedoctoraleducationatKIagain.

Supervisor surveyApilotsurveyaimedatsupervisorswasconductedinordertoassesstheself-perceivedperformance.Theresultsshowedthatthesupervisors’ownperceptionoftheirworkwasconsistentwiththeexpectationsofthesupervisors’role.

Alumni survey of doctoral graduates at KI 2003/2004 and 2007/2008Inautumn2011,KI,togetherwiththemedicalfacultiesatuni-versitiesinGothenburg,Linköping,LundandUmeå,conductedanalumnisurvey.In2012,aninterimreportwascompiled,entitled”PhDsatKarolinskaInstitutet–theirresearchtrainingandentryintothelabourmarket”.

Theresponseswereconsistentwiththeresultsfromtheotherparticipatingmedicalfaculties.90percentofthedoctoralgraduatesfromKIwereemployed.Amongthosewhohadfoundemployment,morethan40percentworkedwithinuniversitiesandhighereducationinstitutionsand,ofthese,94percentstatedthatresearchwaspartoftheirworkduties.Lessthanathirdworkedwithinacountycouncilandaround20percentworkedwithintheprivatesector.Ofallthedoctoralgraduates,81percentstatedthattheirworkwasconnectedwiththefieldoftheirdoctoralstudies,and16percentworkedwithinanotherresearchfieldorarea.Morethan90percentweresatisfiedwiththeirdoctoraleducationandthreeoutoffourrespondedthattheyhadreceivedgoodsupervisionduringtheeducation.

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38 Karolinska Institutet Annual Report 2012

Internationalisation: research and doctoral education

New doctoral education collaboration with Stellenbosch UniversityAcomprehensiveMemorandumofUnderstandingwassignedbetweenKIandStellenboschUniversityin2011.Inordertodevelopanddeepenthiscollaboration,acooperationagreementrelatingtodoctoraleducationwassignedin2012.

Thepartnershipmeansthatdoctoralstudentscarryouttheirdoctoraleducationatbothuniversities,withsupervisorsfrombothStellenboschUniversityandKI.TheeducationisconcludedwiththedoctoralstudentsbeingawardedaPhDdegreefrombothuniversities(doubledegree).

Donation allows postdoctoral programme with the University of TorontoIn2012,formernationalteamplayerandNHLicehockeyprofessionalMatsSundindonatedasumequivalenttoSEK2.2milliontoKIandtheUniversityofTorontofortheestablishmentof”TheMatsSundinAward”.Itisapostdoctoralprogrammeforelitemedicalresearch,whereyoungpost-doctoralresearchersfromKItogetherwithcolleaguesfromtheUniversityofTorontowillconductresearchonchildhealthanddevelopment(DevelopmentHealth).

National Institutes of Health (NIH)Since2001,KIhashadanestablisheddoctoralstudentcollaborationwithNIHwithinthefieldofneurosciencewhich,inrelationtothenumberofdoctoralstudentsandfunding,constitutesthesecondlargestcollaborationconcerningdoctoraleducationatKI.DoctoralstudentsalternatebetweenKIand

NIHandaresupervisedbysupervisorsfrombothorganisations.In2012,fournewdoctoralstudentswererecruitedtojointresearchprojects.AjointKI-NIHsymposiumwasheldinOctoberatNIH.Doctoralstudents,supervisorsandscientificcoordinatorsatKIandNIHallparticipatedinthesymposium.

Activities in SingaporeKIhashadanextendedcollaborationwithNanyangTechno-logicalUniversity,NationalUniversityofSingaporeandtheAgencyforScience,TechnologyandResearch(A*STAR)inSingapore.TwojointsymposiumswereheldinSingaporeinSeptemberregardingmicrobesresearch,metabolism,regenerativemedicineandcancerresearch.Inconjunctionwiththesymposium,ameetingofalumniwasalsoarrangedforformerstudentsanddoctoralstudentsfromSingapore.

Rockefeller UniversityKIcollaborateswithRockefellerUniversityintheformofapostdoctoralexchangeagreementandthroughthelectureprogrammeNicholsonLectures.Theselecturesareheldalternatelyatthetwouniversities.

Doctoral WeekKIhostedDoctoralWeekinautumn2012,aneventarrangedannuallybytheEuropeanUniversityAssociation.Theconferencefocusedonthreecurrentissuesindoctoraleducation:inter-nationaltrends,fundingandqualityassurance.Approximately200visitorsfromaroundtheworldparticipatedinthisevent.

Equal opportunities: research and doctoral education

Theproportionofnewlyrecruitedprofessorswhoarewomenwillriseto47percentfortheperiod2012–2015.Toachievethisaspectofthegovernment’sestablishedrecruitmentgoals,aworkgroupwasformedinautumn2012todevelopaspecificactionplanwithmeasurestoachieveabettergenderbalance,bothintheshort-andlong-term.

InApril2012,theproject”Parenthoodandanacademiccareer?AstudyofparenthoodamongdoctoralstudentsatKI”wasconcluded.ThisprojectalsoaimedatachievingamoreevengenderdistributionamongtheprofessorsatKI.Thestudyexaminedhowdoctoralstudentsviewdoctoraleducationincombinationwithparenthood,theopportunitiesandobstaclestheyperceiveandwhatKIcandotofacilitateparentingasadoctoralstudent.

TheDelegationforGenderEqualityinHigherEducationhasapprovedfundsforanothergenderequalityprojectatKI,”Mentor4Equality”.ThisprojectinvestigatestheconditionsforpursuingaresearchcareeratKIbasedonagenderperspective.Themaingoaloftheprojectistogenerateknowledgeonthemechanismsandstructuresthatpreventgenderequalityin

thecontextofdoctoraleducationandthepostdoctoralperiod.Duringthecourseof2012,theparticipantsintheprogrammehaveobservedvariousformsofunequaltreatmentatKI.Theyhavealsoexaminedimagesandsymbolsfromagenderperspective.Thepervasivenessofmaledominancehasbeenperceivedtobeoverwhelming.Agroupofparticipantshasalsoexaminedseveralyears’copiesofKI’snewsmagazineKIBladet,andhowmenandwomenarepresentedinimages.

Since2010,afeatureonequalopportunitieshasbeenincludedinthemandatoryintroductionforallnewlyadmitteddoctoralstudents.Withinsupervisortraining,whichismandatoryfornewsupervisors,therearealsocoursesongenderequalityissuesandequaltreatment.Atotalof180participantshavetakenpartinthefoundationcourse,48haveparticipatedintheresearchsupervisorcourseand24havetakenpartintheleadershipcourse.

Duringtheautumntermof2012,workshopswereorganisedforthedepartments’StudyDirectorsfordoctoraleducation,regardingequalityandthehandlingofcasesinvol-vingdiscriminationandharassment.

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Common to all operations

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40 Karolinska Institutet Annual Report 2012

Theoperationalareasofresearchanddoctoraleducationarereported,includingfundingformedicaltrainingandresearchandassetmanagement.Furtherinformationcanbefoundunderthefinancialreport.AcorrectionofSEK30.3millionhasbeenmadetothe2011externalfundingonaccountofamodifiedaccountingprinciplefordoctorswithcombinedpositions.SeeNotes2and5.

Co-financingIncaseswhereexternalfinanciersdonotprovidefullfundingforresearchprojects,KIisobligedtoco-financetheprojectby

othermeansinordertocoverthefullcosts.Duringtheyear,directgovernmentfundinghasbeenusedfortheco-financingofgrant-fundedresearchamountingtoSEK60,5million(SEK53.8million),whichcorrespondstoapproximatelythreepercent(3percent)ofthetotalgrantfunding.

Unallocated revenue and costsProfitfromsharesinsubsidiariesandassociatedcompanies,aswellasrevenuecollectionoperations,isnotdistributedwithinlinesofbusiness.SeetherevenuestatementunderthesectionFinancialreport.

Total for research and doctoral education (including asset management), SEK millions

2009 2010 2011 2012

Revenue

Direct government funding 1,326.0 1,581.5 1,630.1 1,732.4

Fees and other remuneration 750.2 696.8 641.0 670.1

Grants 1,925.6 2,095.0 2,077.6 2,234.6

Financial 24.9 29.1 65.6 54.9

Total revenue 4,026.7 4,402.4 4,414.3 4,692.0

Costs

Staff 2,074.9 2,171.7 2,265.2 2,363.5

Premises 452.2 465.0 486.7 557.7

Other operations 1,251.0 1,364.0 1,326.7 1,433.2

Financial -13.5 7.4 28.3 8.9

Depreciation 120.4 134.1 157.2 177.8

Total costs 3,885.0 4,142.2 4,264.1 4,541.1

Transfers

Government funding 0.0 6.1 13.2 12.2

Funding from other government agencies 24.9 20.9 29.6 34.7

Other funding 20.0 35.5 82.9 84.7

Contributions paid -44.9 -62.5 -125.7 -131.6

Change in capital for the year

Annum 141.7 260.2 150.2 150.9

Balanced (IB) 411.1 552.9 813.1 954.3

Total (UB) 552.8 813.1 963.3 1,105.2

Source: Agresso

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Karolinska Institutet Annual Report 2012 41

Collaboration and innovation

IntroductionKarolinskaInstitutet(KI)collaboratesextensivelywithhighereducationinstitutions,hospitals,governmentagencies,companiesandorganisationsworldwide.Thiskindofco-operationisaprerequisiteforasuccessfuluniversity.Thecollaborationisbasedonthemanyinitiativestakenbyindividualteachers,researchersandresearchgroupsatthedepartments.Thefollowingsectionpresentsexamplesofjointcollaborationsorganisedattheinstitutionlevel.

KIisthelargestacademicpartnerinSwedenforresearchersinothercountries.KI’ssinglelargestpartner,StockholmCountyCouncil(SCC),isapivotalfacilitatorofimportantclinicalresearchandeducation.MorethanhalfofKI’soperationsareconductedintheclinicalenvironmentsofhospitalsandothermedicalfacilities.

KIisfoundwithinaknowledge-intensiveareafortheMedicineandlifesciencesinStockholm,closetotheUniversityHospitals,KISciencePark,KIHoldingAB,ScienceforLifeLaboratory(SciLifeLab),theSwedishInstituteforCommunicableDiseaseControlandtheEuropeanCentreforDiseasePreventionandControl,ECDC.

Withintheregion,KIalsocollaborateswithKTH,StockholmUniversity,SödertörnUniversity,StockholmSchoolofEconomicsandUppsalaUniversity.KIisalsoinvolvedinStockholmScienceCityandFlemingsbergScience.

Collaboration with Stockholm County CouncilTheobjectiveofthecollaborationbetweenKIandSCCistoimprovehealthandmedicalcarethroughresearchandeducation.TheextensiverestructuringofhealthandmedicalcareintheStockholmregionrequiresanintensifiedcollaborationbetweenKIandSCC,bothfromaholisticperspectiveandatdifferentorganisationallevels.

Distribution of resources Withintheframeworkofthecooperationorganisation,KI/SCCallocatestheresourcesforresearch,educationanddevelopment.ThisincludesALFfunding(remunerationtoSCCformedicaltrainingandclinicalresearch)andtheappropriatedfundsthatSCCsetsasideforthiscollaboration.Theorganisa-tionalsoreviewsthedistributionofdirectgovernmentfundingforeducationandresearchassignedtoKI.

R&D group/community

Karolinska Institutet KI

Stockholm County CouncilSCC

Management GroupKI/SCC

The Research Strategy Committee

The Infrastructure Committee

Board of higher education

Management level

Operational level

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42 Karolinska Institutet Annual Report 2012

Initiativesin2012includedtargetedinvestmentsinthematiccentres,theidentificationandrecruitmentofnewresearchers,resourcesupporttobothprominentprofessorsandyoungerresearchersandthestrengtheningofcorefacilities.Evaluationswerealsoperformedonthematiccentresandcorefacilities.KIhas45AdjunctProfessorswhoarecofinancedbySCC(October2012).

Education collaborationTheCentreforClinicalEducation(CCE)hasoverallresponsibilityfortheregionalcoordinationofplacementswithinthecounty’shealthandmedicalcare.Overthecourseoftheyear,CCE’steacher’sacademyhasbeenfurtherdeveloped,constitutingacommonmeetingplaceforteachersandsuper-visors.Aspartofeffortstointegrateresearch,educationanddevelopmentinprimarycare,fouracademicmedicalcentreshavebeenbuiltduringtheyear.Fouradditionalcentreshavealsobeenplanned.

The Infrastructure Committee TheInfrastructureCommitteecoordinates,initiatesandinsomecasesfinancesinvestmentsandoperatingcostswithintheareasofpropertydevelopment,animaltestingfacilities,biobanks,

informaticsandlearningenvironments.TheCouncilprovidesstrategicguidancefortheorganisationsrespectively.In2012,resourceswereconcentratedwithintwokeyareas;informaticsandbiobanks.

Furthermore,theFutureLearningEnvironmentsprojectentereditsfinalstagethroughthecompletionofanumberofenvironments(alsoseethesection”Bachelor’s(first-cycle)andMaster’s(second-cycle)education”).

CentreforPharmacoepidemiologyandtheCentreforAdvancedMedicalSimulationandTraininghavealsoreceivedsupportfromtheCouncil.

Faster path to utilisationInthespringof2012,Project4D(fourdiagnoses)wasinitiatedinordertoimproveconditionsforclinicalresearchanddevelop-mentinhealthandmedicalcare.Theaimoftheprojectisalsotoinvestigatehowtheresultsofclinicalresearchcanbeutilisedmorerapidlyintonewandimprovedtreatments,aswellastostrengthencollaborationwithpharmaceuticalandbiotechnologycompanies.Strategiesaredevelopedbyprojectgroupswithintheareasofheartfailureandthromboembolism,rheumatology,type2diabetes,breastcancerandinaprojectoninformatics.

Inaccordancewiththepublicserviceagreement,KIhassubmittedinformationtotheMinistryofEducationandResearchregar-dingtheallocationof2012’sALFfundsasfollows:Staffcosts58.2percent,Premisescosts16.2percentandOthercosts25.6percent.

Information disseminationKarolinskaInstitutetisdedicatedtodisseminatetheknowledgedevelopedattheuniversitytothepublicandprivatesectorsandtothegeneralpublic.Researchfindingsarecommunicatedtothewidercommunitythrough,forexample,variousformsofmedia.In2012,KIwasmentionedonaverage47timesadayintheSwedishnationalpress,localpress,weeklypress,newswebsitesandbroadcastmedia,amassingatotalof17,000times.KIwasalsomentionedover16,000timesininternationalmedia(Source:Retriever).Since1994,KIhasproducedMedicalScience,apopularsciencemagazineissuedquarterly,withacirculationof22,600.Duringtheyear,KIhasalsopublishedanEnglishcollectionedition.ManyoftheKI’sresearchers

andteachers,inadditiontotheirregularassignments,arealsoinvolvedinpublicdebateasauthorsofjournalarticlesandbooks,aslecturers,andthroughparticipationintradefairsandconferences.

In2012,KIparticipatedinseveralcollaborativeprojectsaimedatdisseminatingknowledgetoawiderpublic,includingaseriesoflecturesfortheSwedishPublicEducationalBroadcastingCompanyandthePublicTVKnowledgeChannel,aresearchcompetitionforchildrenincollaborationwiththemagazineKamratposten,andtheactivitydayForskarFredag(TheScientist’sFriday)incooperationwiththeassociationPublicandScience,whichattractedabout5,500visitors.

Innovation support and collaboration with the private sector AgreatdealoftheresearchdoneatKIisconductedincollaborationwithSwedishandoverseascompanies,whichprovidesconsiderableknowledge-exchangeopportunitiesandsourcesoffinancing.In2012,theprivatesectorinvested

Development of RE&D funds at SCC, 2009–2012, SEK millions

2009 2010 2011 2012

Revenue

ALF funds 542.2 562.7 566.6 574.4

SCC funds 1,008.2 1,046.4 983.9 1,010.7

External funds 269.2 177.2 308.5 219.2

Total revenue 1,819.6 1,786.3 1,859.0 1,804.3

Source: report from Stockholm County Council, SCC

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Karolinska Institutet Annual Report 2012 43

SEK274millioninresearchatKI,ofwhichSEK76millionbycompaniesbasedabroad.KIofferscontracteducationwhich,in2012,amountedtoSEK63million,morethan20percentofwhichwasfromclientswithintheprivatesector.

SciLifeLabInspring2012,thegovernmentannouncedthatSciLifeLab–runjointlybyKI,KTH,StockholmUniversityandUppsalaUniversity–wouldbecomeanationalresearchcentrefrom2013onwards.Inadditiontothefundsallocatedbythegovernment,theKnutandAliceWallenbergFoundationwillalsoinvestintechnologylaboratoriesinSciLifeLab.ThepharmaceuticalcompanyAstraZenecaaimstoinvestSEK40-80millionayear,overthenextfiveyears,inresearchprojectswithintheframeworkofSciLifeLab.Thiscompany,likemanyotherpharmacompanies,hasrecentlyrestructuredtheirportfoliosofresearchandresearchfacilities.AstraZenecaannouncedearlierinthespringthat,during2012,thecompanywillphaseoutresearchatseveralfacilitiesintheworld,includinginSödertälje.

KI HoldingKarolinskaInstitutetHoldingAB(KIHAB)owns,sellsandmanagessharesandparticipationsinprojectandservice

companies,thepurposeofwhichistoputknowledgeandresearchresultstogoodusebycommerciallyexploitingtheprojectsorknowledgeproducedfromKarolinskaInstitutet.KIHABhasfourwhollyownedsubsidiaries:KarolinskaInstitutetInnovationsAB,KarolinskaInstitutetScienceParkAB,KarolinskaInstitutetUniversityPressAB,andKarolinskaInstitutetHousingAB.Theconsolidatedturnoverin2102wasSEK43million(SEK46million).ThegroupsoperatingresultwasSEK-32million(SEK-8million),partlyduetopoorstockperformance.

ThegovernmenthaspreviouslyallocatedSEK9milliontoKItobeusedfortheutilisationofresearchfindings.ThesefundsweretransferredtoKIHABasshareholdercontributionsfollowingacorporatereview,inaccordancewiththepublicserviceagreementfor2009.During2011and2012,KIHABtransferredtheentireamountasagroupcontributiontoKIInnovationsABandKIScienceParkAB.

Companiesseekingcollaborationwithresearchers,orresearcherswhowishtocollaboratewithcompaniesordevelopcommerciallyviableideas,areofferedsupportfromKI’sinnovationsystemwhichiscomprisedoffivekeyactors.

Unit for Bioentrepreneurship

Research and education in entrepreneurship.

The Innovation Office

Support for private sector collaboration, information and guidance in innovation issues.

Karolinska Institutet Innovations AB

Incubator. Support for commercialisations and corporatisations. Licensing. Mature companies are sold to market participants, including Karolinska Development.

Karolinska Institutet Science Park AB

Provides premises, installations and Facility Management for life science companies.

Karolinska Development AB

Investment firm with a company portfolio, several originating from KI Innovations AB.

Education and research within innovation and entrepreneurshipTheUnitforbioentrepreneurship(UBE)isanacademicunitatKIfocusingoneducation,developmentandresearch,includingatwo-yearinternationalMaster’sprogramme.Duringtheyear,aprojectaimingtoimplemententrepreneurshipatKI’sfirstcycleprogrammeshasbeenlaunchedatelevenofKI’sfirstcycleprogrammes.In2012,UBEreceivedgrantsfromtheSöderbergFoundation;tostudyopeninnovationbetweenindustryandacademia,thehealthcareinnovationsystemandthefurtherdevelopmentofmanagementeducationforfuturedoctors.

Service for ideas, advice and enterprisesThroughtheInnovationOffice,KIoffersresearchersandstudentssupportwithideadevelopmentandcollaborationwiththeprivatesector.Italsooffersguidanceforcompaniesseekingacademicpartners.TheInnovationOfficehasbeenfinanced

withseparatestatefunding;SEK5millionfortheperiod2009–2011,andSEK7.3millionfor2012.KIhasmatchedthisfigurewithfundsfromitsownresources.During2012,135advisorycaseswerehandledbytheInnovationOffice,110ofwhichwererelatedtoadvicearoundearlyphaseideasand25wererelatedtobusinesscollaborationsbasedonestablishedresearchatKI(23in2011).TheInnovationOfficeworkstogetherwithUpp-salaUniversityingivingpatentadviceandwithUppsalaBioaroundBio-Xprojectapplications.

TheInnovationOfficeisalsopartneredwithKTHintheKunskapslotsenprojectandcollaborateswithSödertörnUniversityontheEntréQproject.SinceitsestablishmentinNovember2010,theInnovationOfficehas,bywayoftradefairs,seminars,departmentvisits,etc.,hadcontactwith3,512peoplewiththeaimofraisingawarenessandincreasingtheflowofideas.

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44 Karolinska Institutet Annual Report 2012

KI’s incubator for commercial projectsKIhasanincubatorofferingcommercialadviceandprojectmanagementintheformofKarolinskaInstitutetInnovationsAB.ResearchbasedideasfromresearchersatKIandotherresearchinstitutionsintheNordiccountriesareevaluatedhere.In2012,KIInnovationsABevaluated77ideasandhad11activeprojectsattheturnoftheyear.KIInnovationsABisresponsiblefortheallocationoffundsfromVinnovatopromisingresearchfindingsinordertoevaluatecommercialpotential.

KIInnovationsABhasevaluatedmorethan1,300ideassincethecompanywasformedin1996.

KI Science ParkKarolinskaInstitutetScienceParkABislocatedbothinSolnaandinFlemingsberg.InDecember2012therewere63companiesintheKIScienceParkemployingatotalof420people.

KIScienceParkoffersbusinessesbothhardandsoftinfrastructure,ameetingplaceforknowledgetransferandexperienceexchange,andLifeScience-specificsupportfunctions.TogetherwithSödertörnUniversity,KIScienceParkalsorunsaservicesectorincubatorinFlemingsberg,whereforexampletwoprojectsfromAstraZenecaarereceivinghelpingettingtheiroperationsofftheground.GrantshavebeenobtainedfromtheEUtodevelopaddedvalueforthecompanies.

In2012,ScienceParkarranged31seminaractivitieswithatotalof540participants.

Karolinska Development AB – a listed investment company KarolinskaDevelopment’sgoalistocreatevalueforinvestors,patientsandresearchersbydevelopinginnovationsfromworldclassscienceintoproductsthatcanbesoldorout-licensedwithhighreturns.Theportfolio,whichon31December2012com-prised34projects,15ofwhichwereinclinicaldevelopment,isstrongwithinthefieldsofcancerandotherareasofsignificantmedicalneed.SinceApril2011,theKarolinskaDevelopmentsharehasbeenquotedonNASDAQOMXStockholm(ticker:KDEV).

Flemingsberg Science FoundationAsKIannouncedinthe2011AnnualReport,KIhasthisyearappliedtothegovernmentforsupportfortheFlemingsbergScienceFoundationbywayoftheStockholmScienceCityFoundation.TheaimistosupportthedevelopmentoftheFlemingsbergareaasaresearchandeducationalenvironment.

Accordingtoinformation,thematteriscurrentlybeingprocessedintheGovernmentOffices.In2012,KIhaspaidsupportpursuanttotheaboveintheamountofSEK0.5million.

Selected key ratios: collaboration, number/SEK millions/% 2009 2010 2011 2012

A Externally financed research, total 2,731 2,824 2,792 2,935

– from companies, total 296 265 250 241

– from overseas companies 100 69 79 73

B Contract research 567 425 422 395

– from companies, total 177 133 129 124

C Contract education, total revenue 50 51 69 63

– from companies, total 15 17 17 14

D Contract education (FTE students) 180 178 235 250

E Adjunct Professors (headcount) 69 52 57 64

– of which are financed by SCC 42 38 42 45

F Doctoral students employed in the private sector

and public organisations (annual working units) 416 419 442 452

G EU projects (FP6, FP7 och EU health programme) 230 204 222 234

– as coordinator 38 29 31 21

H Ideas advice cases treated at KI Innovations AB

and the Innovation Office 88 97 157 178

I KI Innovations AB active projects at turn of year 29 21 13 11

J Companies within KI Science Park 53 56 65 63

K Employed by companies within KI Science Park* 145 585 580 420

L Scientific articles, percentage co-published with

parties outside of KI (%) 82 82 84 83

M Scientific articles, percentage co-published with

parties outside of Sweden (%) 60 60 62 63

Sources: A-D: Ekonomisystemet Agresso. E: KI Academic Appointments and Announcements Office, F: Ladok Student Database, G: KI Researcher Support Office,

H-K: Data from respective operations, L, M: University Library (Web of Science). H refers to the net number, 43 of which are funded by Vinnova’s programme

Verification for Growth. Advice for early phase ideas, established at the Innovation Office from 2011. Data for 2009 and 2010 relating only to KI Innovations AB.

Note: The decline in B, Contract research, is partly due to a modified accounting principle with regard to funding from SCC.

*Data on the number of employees is collected by survey.

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InternationalisationQuality

Equal opportunitiesSustainable development

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46 Karolinska Institutet Annual Report 2012

01–1011–5051–200201–1 0001000 +

InternationalisationactivitieswithinKIaimtoimprovequalityanddiversitywithinresearch,educationandadministration,withthegoalofstrengtheningtheuniversity’scompetitiveness.AtKI,thereisalongtraditionofinternationalcontactsandscientificexchangeswithresearchers,teachers,doctoralstudentsandstudentsinothercountries.Themapshowsanoverviewofinternationalcollaborationsintermsofthenumberofcopublicationswithdifferentcountries.

New cooperation agreements have been signedMuchofKI’sresearchisconductedincollaborationwithpartnersaroundtheworld.Forthemostpart,collaborativeinteractionsbetweenindividualresearchersandresearchgroupstakesplacewithoutagreementsgoverningthecooperation.Insomecases,however,thereisaneedtostrengthenstrategicresearchfieldsandeducationalcollaborationsthroughformalcooperationagreements,withtheaimofcreatingstrongandstablelinksbetweenthepartnerinstitutions.2012sawthesigningofcomprehensivedeclarationsofintentoragreementsonco-operationwithinresearchand/oreducationwith,amongothers,StellenboschUniversityinSouthAfrica,theChineseUniversityofHongKongandtheUniversityofIllinois.Enhanced co-operation with the Mayo ClinicIn2011,KIandtheMayoClinic,USA,decidedtodeepenandbroadentheirco-operationwithinresearch,education,administrationandinnovation.Anoperationalsteeringgroupwascreatedtoworkwiththestrategicplanningwhichthisentailed.Withintheframeworkofthecooperation,theopportunitytoapplyforfundsfortravelexpensesrelatedtocooperationprojectswasannouncedforthefirsttimein

December.Jointmeetingshavealsotakenplacethroughouttheyear.Forexample,theMayoClinicwasvisitedbythepresidentalongwithmembersofKI’smanagementandStockholmCountyCouncil’spoliticalleadership.Duringtheyear,anannualjointmeetingwasarrangedinRochesterwithatotalofapproximately100participants,whereresearch,educationandinnovationwerethetopicsofdiscussion.

International visits and delegation missionsEachyear,KIreceivesalargenumberofvisitrequestsfromuniversitiesandotherorganisations.Duringtheyear,delegationsfromuniversitiesinBrazil,Australia,HongKong,JapanandUganda,tonamebutafew,havepaidavisittoKI.Inaddition,KIhasreceivedvisitsfrom,amongothers,Canada’sMinisterofHealth,theWHOSecretary-GeneralandthePresidentofFinland.

Thisyear,severaldelegationmissionswerecarriedouttodifferentpartsoftheworld,includingvisitstotheChineseUniversityofHongKongandSeoulNationalUniversity.KIalsosentrepresentativestoShanghaiJiaoTongUniversity,theSchoolofMedicine’s60thanniversary,andtoPekingUniversityHealthScienceCenter’s100-yearanniversary.

Erasmus MundusKIiscurrentlypartofanumberofErasmusMunduscollabo-rationsinvolving,forexample,India,SouthAfricaandEurope.ErasmusMundusisanEU-fundedcooperationandmobilityprogrammeinthefieldofhighereducation,operatinginconsortiaofEuropeanandnon-Europeaneducationalinstitutions.

Co-publication countries for Karolinska Institutet researchers 2009–2012Certain data included herein are derived from th Web of Science prepared by THOMSON REUTERS, Inc (Thomson), Philadelphia, Pennsylvania, USA: THOMSON REUTERS 2011. All rights reserved.

Number of publications

Long standing tradition of international contacts and scientific exchanges

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Quality

Karolinska Institutet Annual Report 2012 47

In2012,KIwasgrantedcontinuedfundingformobilityanddegree-awardingeducationalprogrammesatadoctorallevelincollaborationwiththeUniversityofSouthAfrica.

Inaddition,aone-yearMaster’sprogrammeisbeinginitiated–PublicHealthinDisasters–togetherwiththeuniversityofOviedoochUniversitécatholiquedeLouvain.Theprogrammewillbegininautumn2013andwillleadtoajointdegreebetweenKIandtheUniversityofOviedo.

Organisation of internationalisation issuesTheinternaloperationalboardsforhighereducation,researchanddoctoraleducationareresponsibleforinternationalisationwithintherespectiveareasofresponsibility.Inaddition,thereisanInternationalStrategyCommittee(IS)specificallyresponsibleforstrategicinternationalisationissues.TheCommittee’smissionistocoordinatetheinternationalisationeffortsatKI,whichinvolvesprioritisingtheproposalsreceivedonuniversity-widecollaborations.

ThedeparturepointforqualityworkatKIisthattheoperationscancontinuallybeimproved.Aprerequisiteforachievingsuccessfulqualityworkisthatitisanintegratedpartofregularoperations.Therequirementsforqualityareformulatedinvariouspolicyandstrategydocuments.Theresponsibilityforqualitywithincoreoperationslieswiththethreeoperationalboards.

EvaluationExternalevaluationshaveaffectedthisyear’sactivitiesbothwithinresearchandeducation.TheresultsoftheexternalevaluationofKI’sresearch(ERA)havebeenfollowedupduringthecourseoftheyear.

In2012,theSwedishNationalAgencyforHigherEducationauditedtenoftheUniversity’sfirst-cycleandsecond-cycleprogrammes.Experiencesgainedfromtheseevaluationswillbetakenintoconsiderationintheon-goingqualitywork.Alsoseethesection”Bachelor’s(first-cycle)andMaster’s(second-cycle)education”.

Operational management Adetailedriskanalysishasbeencarriedoutduringtheyear.ThisriskassessmenthascreatedacommonpictureofwheremeasuresneedtobetakeninordertoachieveKI’sgoals,therebyexposingsignificantqualitydeficienciesintheoperations.Throughtheplanningandmonitoringofeachoperation,con-trolmeasuresaretakeninordertomanagetheidentifiedriskareas.Alsoseethesection”Internalmanagementandcontrol”.Anon-goingreviewofKI’smanagementmodelhasbeenconductedduringtheyearinordertoimproveandassurethequalityofoperationalplanningandinternalcontrol.

Effortstodevelopqualityindicatorshavecontinuedwiththecirculationofproposalsfortheconsiderationofthepartiesinvolved.In2013,theseindicatorscouldbeemployedinconnectionwithqualitycontrol.ImplementationoftheOperationsInformationSystem(VIS)hasbeenunderwayduringtheyearandthefirstparthasalreadybeenlaunched.Thismakesitpossibletomonitoreducationalmissionsaswellascertainstaffstatistics.Thesystemshouldenableaccesstokeyratios,qualityindicatorsandquantitativeinformationonKIandthedepartments’activities.

OrganisationBasedonefficiencyandsavingsrequirements,theUniversityAdministrationhasconductedanorganisationalreviewinautumn2012.Theaimsoftheneworganisation,whichentersintoeffectinMarch2013,includeprovidingeffectiveandqualitativesupporttothecoreoperationsandoperationalboardsaswellasincreasedresultsorientation.Theorganisationwillalsoendeavourtoincreasecoordinationinordertofacilitateabetterresponsetoimportantrecommendationsreceivedfromauditbodies.Furtherdescriptionsofqualityworkcanbefoundundertherespectiveoperationalareas.

Quality an integrated part of operations

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Equal opportunities

48 Karolinska Institutet Annual Report 2012

KIworksactivelyandpurposefullytoachieveequaloppor-tunitiesforemployeesandstudents.ThisworkisbasedonthecriteriafordiscriminationasdictatedbytheDiscriminationAct.Duringtheperiod2012–2015,muchattentionisgiventothesubjectofgender,withrespecttodiscriminatorypractices.Thereasonforthisisthatthegovernmenthasestablishedarecruitmentgoalforprofessorswhich,inKI’scase,meansthat47percentofnewlyrecruitedprofessorsshouldbewomen.

OrganisationThePresidenthastheultimateresponsibilityforensuringthattargetedequalityworkisconductedatKI.

TheCouncilforEqualOpportunities,whichisdirectlysubordinatetothePresident,engagesinstrategicinitiativesbasedonthesevencriteriafordiscriminationstipulatedintheDiscriminationAct.

TheCouncilincludesrepresentativesfromtheoperationalboards,departmentsandUniversityAdministration,studentunionsandunionorganisations.TheCouncilworksinageneralcapacitybutalsoprovidesdirecttosupporttodepartmentsandprogrammesetc.

Itstasksincludethedevelopmentofanactionplanforequalopportunities.TheCouncilalsoactsasasupportfunctionforthePresidentwithregardtoreferralsandinvestigationsconsideredrelevantforequalopportunities.Atthedepartmentallevel,theHeadofDepartmentisresponsibleforworkpertainingtoequalopportunities.Therearealsooneormoreequalopportunitiesrepresentativesfoundateachdepartment.

Gender distribution in drafting and decision-making bodies as well as at management level TheproportionofwomenamongDeansandViceDeanswas17percentattheendof2012;allDeansandtwooutofthreeViceDeansaremen.Thegenderdistributionamongoperationalboardmembersiscalculatedtobewithintherangeof40–60percent.TheproportionofwomeninKI’sManagementGrouphasdroppedfrom56percentin2011to33percentin2012.

Inaccordancewiththecurrentregulationsforheadofdepartmentassignmentandformsforrecruitmentofdepartmentheads,therecruitmentgroupforeachpostingshallselectatleasttwocandidatesforthepositioncomprisingonemanandonewoman.Theproportionofwomenamongdepartmentheadsis32percent,whichrepresentsanincreaseof5percentcomparedwiththepreviousyear.

Launch of online educationInordertoincreaseawarenessandknowledgeofdiscriminationlawandhowKIhandlesandinvestigatesindividualcasesofdiscrimination,aweb-basededucationalprogrammehasbeendeveloped.TheprogrammeisaimedatbothstaffandstudentsatKI.ThisonlineeducationcanbeviewedasanintroductiontotheDiscriminationAct.Togainadeeperknowledgeoflegislation,normsandvalues,KIoffersseminarsandlecturesonequalopportunitiesasithasdoneinthepast.

Project with focus on disabilityInautumn2012,KIinitiatedaprojectwhichfocusesonthediscriminationcriteriondisability.Withinthisproject,measureshavebeenplannedwithintwoareas.

Thisispartlytofacilitateareturntoworkfollowinganillnessthatledtopermanentdisability,andpartlytopreventdiscrimi-nationintherecruitmentcontext.Thesemeasuresarefinancedthroughjointpartysecurityfunds.

SeminarsInadditiontoseminarsandlecturesaimedatspecifictargetgroups,in2012,KIarrangedtheopenlecture”Equalrightsandopportunitiesandaworkenvironmentfreefromdiscrimination–amatterofcourseatKI?”

KIalsoofferedequalityrepresentativestheopportunitytoattendaseminaronagediscriminationintheworkplace.

Furtherdescriptionsofissuessurroundingequalitycanbefoundundertherespectiveoperationalareas,aswellasunderHumanResourcesandcompetencesupply.

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Karolinska Institutet Annual Report 2012 49

Sustainable development

Goodpublichealthisbothaprerequisiteandagoalofsustainabledevelopment.Therearecurrentlysignificantimprovementsbeingmadeinhumanhealthonaglobalscale.Atthesametime,diseasessuchastuberculosis,malariaandHIVposeathreattopublichealthintheworld’spoorerregions,whilecardiovasculardisease,canceranddiabetesimpactthesocietiesofrichercountries.KI’sresearchandeducationhelpidentify,describe,preventandcurethesediseasesandarethereforeofparamountimportanceforsustainabledevelopment.

Duringtheyear,KI’seducationalprogrammescontinuedintheireffortstointegratesustainabledevelopmentintoeducation.Thegoalisforallprogrammestoclarifythesustainabilityissueswhichareofparticularrelevanceandwhetherthereareintendedlearningoutcomesthatconnecttotheseissues.Thepurposeofthisistobettercommunicatetheprogrammes’”sustainabilitycontent”tocurrentandpotentialstudents,andifnecessary,formulatesupplementarycourseelementsandlearningoutcomes.

KI’ssustainabilityworkhasstronglinkstotheUniversity’sworkwithinternationalisation,equalopportunities,entrepreneurshipandethics.Atthisyear’sTeachers’Dayonthethemeof”sustainableeducation”,participantsdiscussedtheneedandopportunitiesforworkinginanintegratedmannerwiththeseareas.

InApril,theMinistryoftheEnvironmentandtheMinistryforForeignAffairshostedtheinternationalconference”Stockholm+40–PartnershipForumforSustainableDevelopment”inmemoryofthefirstUNGlobalConferenceontheHumanEnvironmentinStockholmin1972.Inconjunctionwiththeconference,thegovernmentinvitedSweden’suniversitiesandhighereducationinstitutionstoorganiselocaleventstoemphasisetherelevanceofeducationandresearchforsustainabledevelopment.AnumberofseminarswereorganisedatKIonthethemeofsustainabledevelopment,whereexamplesfromKI’sresearch,educationandcampusworkwerepresented.

Sustainable campusKIalsocontributestosustainabledevelopmentbytakingenvironmentalandsocialresponsibility,realisedinthewayinwhichweconductouroperations.

Withregardtoitslaboratory-intensiveactivities,KIhasarelativelyhighenergyconsumption,whereinthereisscopeforimprovingenergyandenvironmentalperformanceaswellasfinancialsavings.Energyefficiencyisthereforeanimportantrequirementinnewconstructionandrenovation.

Furthermore,KIconductsenergy-savingprojectsinexistingbuildingstogetherwithKI’slandlord.

Inco-operationwiththelandlordAkademiskaHus,KIhascommencedacomprehensiveinitiativeaimedatimprove-

ments,suchastheenergyrecoveryinairconditioningsystemsthroughoutCampusSolna.Theprojectisscheduledtocontinuethrough2013andisexpectedtoprovideenergysavingsofapproximately4,000,000kWh/year,equivalenttoalmostsixpercentofthetotalenergyconsumptionofthepremisesKIrentsfromAkademiskaHus.In2012,effortswerealsointensifiedwithrespecttoaddressingventilatedworkplaceswherenegativeremarksonsafetyfunctionshadbeennoted.Thisworkwillcontinuein2013.MinimalenergyusewithregardtoequipmentandfurnishingshasalsobeenanimportantrequirementfortherenovationofthehousesW-bergandRetzius.

Attheendoftheyear,amajorenergy-savingprojectwasinitiatedinCampusHuddinge.Theprojectwillrununtil2014andisexpectedtoleadtoa40percentlowerenergyconsumptionintheaffectedbuildingatAlfredNobelsallé8.

AnotherpriorityareawithinKI’ssustainabilityworkistominimisetheenvironmentalandhealthriskswithinlaboratoryoperations.Theinternalenvironmentalauditin2011showedthatriskassessmentsregardingworkinlaboratoriesmustbeperformedtoagreaterextentthanisdonetoday.

Theriskassessmentsaimtoensurethatsubstancesharm-fultotheenvironmentalandhealtharehandledinasafeandresponsiblymanner.Inordertoovercomethisshortcoming,severaleducationalandinformationalactivitieshavebeenconducted.

KIaimstoincreasetheproportionofsource-separatedwastesoastoenableahigherdegreeofmaterialrecycling.Thepossibilitiesforstudentstosource-separatetheirwastehavepreviouslybeenlimited,andhavenowbeenimprovedbothonCampusSolnaandinHuddinge.

Management systemAsignificantpartofKI’ssustainabilityworktakesplacewithintheframeworkofKI’sEnvironmentalandsustainabilitymanagementsystem.Thesystemhasbeenbuiltupinaccordancewiththeinternationalstandardforenvironmentalmanagement–ISO14001.

Theyear’senvironmentalauditwithregardtotheserequirementswasconductedduringtheautumn.Theauditrevealedthattheenvironmentalmanagementsystemhasdevelopedpositivelysincethepreviousyear’saudit.Bothknow-ledgeandcommitmentregardingissuesofenvironmentandsustainabledevelopmenthaveincreasedwithintheorganisation

However,effortstoestablishanumberofkeyelementsinthemanagementsystemmustbecontinued,suchastheintroductionofadeviationmanagementsystemanddocumentcontrolprocedures.

Research and education for sustainable development

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Human resources and competence supply

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Karolinska Institutet Annual Report 2012 51

Human resources and competence supply

FTE staff by category

2009 Wmn (%) 2010 Wmn (%) 2011 Wmn (%) 2012 Wmn (%) Change 2011–12

Professor, pre-clinical 188 23 190 28 203 27 214 29 6%

Professor, clinical 140 18 142 20 144 23 153 24 6%

Senior lecturer, pre-clinical 110 60 112 57 134 62 122 62 -9%

Senior lecturer, clinical 38 40 41 49 38 44 37 41 -4%

Research associate 117 51 138 52 165 52 161 51 -3%

Lecturer 219 80 180 75 166 75 159 75 -4%

Senior research fellow 685 50 708 51 741 54 793 53 7%

Doctoral student 515 67 519 65 544 64 572 64 5%

Admin staff 858 84 896 84 971 83 913 84 -6%

Technical staff 1,005 71 1,020 73 1,003 71 1,068 69 6%

Total 3,875 65 3,944 65 4,109 65 4,192 64 2%

Note: The figures above include all employees, regardless of work hours or length of tenure, but exclude people with assistantships linked to postgraduate grants, adjunct or acting teachers, and employees on leave of absence, parental leave, sick leave, early retirement, etc. With regard to the number of other employees, only those on full leave of absence (rather than parental and sick leave) have been omitted. The figures for all employees (FTE and other) refer to October 2011. The calculation of FTEs, however, does not include staff on sick or parental leave, in accordance with Statistics Sweden’s instructions.

InOctober2012,KIhad4,768employees,anincreaseof65whencomparedwiththesameperiodin2011.Thiscorrespondsto4,192annualFTEemployees,anincreaseof83(twopercentagepoints)on2011.

ThelargestpercentageincreasesareattributabletotheSeniorLecturer(pre-clinical)andSeniorResearchFellowcategories.ThecategorySeniorLecturers(pre-clinical)hasdecreasedby12annualFTEemployees,whichcorrespondsto-9percent.ThecategorySeniorResearchFellowshasincreasedby52annualFTEemployees,correspondingto7percent.

Thestaffturnoverforpermanentstaffwasapproximately14percent.Thisrepresentsanincreaseofonepercentagepointcomparedto2012.Thetotalturnoverofstaff,includingstaffonfixed-termcontracts(anddoctoralstudentswithemployment)wasapproximately23percent,whichisanincreaseofonepercentagepoint.Throughouttheyear,347individualshave

beenemployedwithpermanentcontractsand407haveresigned.Inadditiontoemployees,alargenumberofindividualswithoutaformalemploymentarrangementparticipateinKI’soperations.Thisprimarilyincludesvisitingresearchers,scholarshipstudentsandunpaidAssociateProfessors.Furthermore,countycouncilemployees,suchasnurses,physiotherapistsanddoctors,alsoparticipateinresearchandeducation.

InOctober2012,KIhad572doctoralstudentships,whichisanincreaseof28annualFTEemployeescomparedwith2011,and380doctoralstudentswithstudygrants,representinganincreaseof40annualFTEemployees.Ofthosedoctoralstudents,65percent(254individuals)combinedtheirgrantswithanassistantship.Inaddition,therearedoctoralstudentswithalternativesourcesoffunding,suchasscholarships,otheremploymentatKIoranothereducationalinstitutionorthroughclinicalplacement.

Breakdown by genderAsinpreviousyears,abouttwothirdsofemployeesarewomen.Therationoffemaleprofessorsis27percent,whichisanincreaseoflessthantwopercentagepointscomparedto2011.IntheSeniorLecturer,ResearchAssociateandSeniorResearch

Fellowcategories,thegenderdistributionfallswithintheintervalof40–60percent.Amonglecturers,doctoralstudents(employed)andtechnicalandadministrativestaff,womenrepresentanoverwhelmingmajority,evenifamarginalreductioninthegenderimbalanceisnotedwhencomparedto2011.

Report on human resources

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52 Karolinska Institutet Annual Report 2012

Human resources and competence supply

TherighttopromotionwasremovedfromtheHigherEduca-tionOrdinanceasof1January2011,whereinKIchosenottoreinstatetherightorpossibilityofpromotioninitsorderofadmissionsandemployment.Inconnectionwiththeexpiryofthepreviousemploymentplan,arecordnumberofapplications

werereceivedforpromotiontoSeniorLecturerandProfessor,whererecruitmentdecisionshavebeentakenin2011and2012.Despitethelargenumberofpromotedprofessorsin2011,therehasofyetbeennomarkedreductioninprofessorshipsbeingfilledthroughadvertisementin2012.

New teachers

Newly appointed Professors and Senior Lecturers, including promoted

2009 Wmn (%) 2010 Wmn (%) 2011 Wmn (%) 2012 Wmn (%)

Professor

Advertised position 7 0 10 20 6 17 13 15

Promotion 12 42 20 55 26 42 11 55

Guest 2 0 12 17 3 0 3 0

Total 21 24 42 36 35 34 27 30

Senior Lecturer

Advertised position 7 43 11 55 11 55 16 50

Promotion 7 71 12 75 38 79 3 33

Total 14 57 23 65 49 74 19 47

*Including persons who applied for an advertised lectureship but who were promoted directly to Professor, and including persons recruited from a professorship funded by the Swedish Research Council. The number of promoted Senior Lecturers is one less than that of 2011.

Adm personal

Tekn personal

Doktorand

Forskare

Adjunkt

Fo-assistent

Lektor

Professor

Kvinnor (tot 2 678) Män (tot 1 514)

200600800 600200400 0 400 800

Professor

Senior lecturer

Postdoctoral fellow

Junior lecturer

Senior research fellow

Doctoral student

Technical staff

Administrative staff

800 600 400 200 0 200 400 600 800

F 100 M 267 = 367

F 91 M 67 = 159

F 82 M 79 = 161

F 119 M 40 = 159

F 422 M 371 = 793

F 369 M 203 = 572

F 731 M 336 = 1 068

F 762 M 151 = 913

Female, total 2,678

Male, total 1,514

2012 Staff categories: breakdown by gender Total: 4,192

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Karolinska Institutet Annual Report 2012 53

Human resources and competence supply

Adjuncts, professors and senior lecturers

2009 Wmn (%) 2010 Wmn (%) 2011 Wmn (%) 2012 Wmn (%)

Professor

New adjunct position 4 0 8 38 18 28 9 44

Renewed adjunct position 4 25 7 29 16 25 7 17

Total 8 13 15 34 34 27 16 32

Senior lecturer

New Adjunct position 6 33 6 33 13 46 5 40

Renewed Adjunct position 6 0 5 40 2 50 6 33

Total 12 17 11 36 15 47 11 36

ThegovernmenthasestablishedarecruitmentgoalforKIwhereatleast47percentoftheprofessorsemployedduring2012–2015aretobewomen.ThegoalincludespromotedprofessorsandVisitingProfessors,butnotAdjunctProfessors.In2012,theproportionofemployed(includingVisitingProfessors)andpromotedprofessorswhoarewomentotals30percent.ThePresident’sCouncilforEqualOpportunitieshasappointedaworkinggroupmandatedtodevelopproposalsforactivemeasurestoincreasetheproportionofwomenamongnewprofessorsatKI.

ThenumberofSeniorLecturersrecruitedthroughanadvertisedpositionincreasedslightlycomparedtopreviousyears.ThisisdespitethelargenumberofSeniorLecturerswhogainedpositionsthroughpromotionin2011.TheproportionofwomenamongnewlyappointedSeniorLecturersreached47percentin2012.Thefour-yeartrainingpositionofResearch

AssociatewasremovedfromtheHigherEducationOrdinanceinJanuary2011,butduetotransitionrules,newResearchAssociatescouldbeemployeduntil31October2011.ThepositionwasreintroducedintheOrdinanceon15August2012underthetitleteachingpositionforacquisitionofqualifications.Initsorderofadmissionsandemployment,KIhascontinuedtousethetitleResearchAssociateforthisposition.Inautumn2012,KImadeaninvestmentthroughthecentraladvertisementoffundsfor20positionsasResearchAssociate.Additionalfundsareexpectedtobeallocatedtothisendin2013.Duringtheyear,selectionprocedurehasbeenusedononeoccasion.Theselectedprofessorisaman.

Therewere64AdjunctProfessorsattheyear’sendwhichcorrespondsto15annualFTEemployees,aswellas36AdjunctSeniorLecturerscorrespondingto9annualFTEemployees.

Number of teachers holding PhDs and proportion of all teachers, 2009–2012 (annual FTE employees)

Year Number PhD’s Proportion of total (%)

2009 634 78

2010 665 83

2011 707 84

2012 714 84

PostdoctoralThenumberandproportionofteachersholdingPhDsconti-nuestoincrease(annualFTEemployees).ThisgroupincludesProfessors,SeniorLecturers,ResearchAssociatesandAdjuncts.TeacherswhohavenotcompletedadoctorateareonlyfoundintheAdjunctcategory.

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54 Karolinska Institutet Annual Report 2012

Human resources and competence supply

Sickness absence (%) 2009–2012

2009 2010 2011 2012

Total 2.4 2.0 1.9 1.8

Long-term sickness absence 63.7 57.0 48.9 32.1

Women 3.1 2.7 2.4 2.4

Men 1.1 0.9 1.0 0.8

Employees <29 years old 1.6 1.5 1.2 1.2

Employees 30–49 years old 1.8 1.5 1.5 1.6

Employees >50 years old 3.5 2.9 2.7 2.3

Long-term sickness absence relates to a continuous period of sixty days or more of the total sickness absence period. Sickness absence for women and men is stated as a percentage of the combined regular work hours within the group. The figures do not indicate the sickness absence for women and men as a percentage of the total sickness absence. Sickness absence in age groups is calculated correspondingly.

Sickness absenceSicknessabsencecontinuestodecreaseoverallduring2012,themostsignificantchangerelatingtolong-termsicknessabsence.LikelyreasonsincludechangesimplementedintheregulationsandthefactthatKIworksproactivelywithrehabilitation.In

general,KIhasalowlevelofsicknessabsencebutthedata,inparticularfromshort-termabsence,canbeuncertainduetotheacademicstaff ’sworkhoursnotbeingregulatedtothesameextentasotherstaff.Insomecases,thedayofqualifyingperiodisexchangedforholidaydaysorcompensatoryleave.

InaccordancewiththeAnnualReportsandBudgetDocumentationOrdinance(2000:605),allgovernmentagenciesmustreportandanalysethemeasurestakeninordertoensurethattherequiredcompetenceisavailabletoachievethegoalsoftheoperation.

Inordertoattract,recruitandretaincompetence,KIwishestohighlightactionswithinthefollowingareas:• Recruitmentandmanpower• Leadershipdevelopment• Workenvironmentandhealth• VisitingResearcherServices• Participationandinfluence

Recruitment and manpowerTheprocessof”Supportforthedevelopmentofmanpowerplans”hascometoanend.ThesystemsupportfunctionformappingtheformaleducationforemployeesatKIhasbeendeveloped,andmuchofthisinformationhasbeencollected.However,worktodevelopasystemsupportfunctioninordertoproducecomprehensivemanpowerplanshasnotyetbeencompleted.

Anewrecruitmentsystem,NetRecruiter,hasenteredintooperationduringtheyear.Thepurposeofthesystemistosupportthecommonrecruitmentprocessdevelopedinthe

formofaweb-basedrecruitmentguide,whichaimstoimprovetheefficiencyandqualityassuranceofKI’srecruitmentsandshortenleadtimes.ThedevelopmentofKI’srecruitmentprocess/guidehascontinuedthroughouttheyear.

WorkwithinrecruitmenthasalsoincludedEmployerbrandingintheformofagreementswithvarioussocialmedia,wheretextsandfilmshavebeenproduced.KIhasalsoparticipatedinvariousjobfairsandsimilarevents.Inaddition,therecruitmentfeatureofKI’sexternalwebsitehasbeendevelopedinordertoattractpotentialemployees.

Introductionprogrammesareconductedeachtermforallnewemployeeswithinalloccupationalcategories,andspecificindividualintroductionprogrammesarebeingdevelopedbynewheadsofadministrationthatincludeamentorsystemtofacilitatetheacclimatisationofnewemployees.

Oneprojectrelatingtotheadvertisementandrecruitmentofdoctoralpositionsisalsounderway.TheaimisforKItocompetitivelyreleasethedoctoralpositionsandco-announcetheadvertisements.Thedateoftheintroductionisplannedfor2014.

Leadership development Abasicrangeofleadershipdevelopmentprogrammeshavebeenofferedandconductedduringtheyear,includingtheNational

Sickness absence

Reporting of competence supply

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Karolinska Institutet Annual Report 2012 55

Human resources and competence supply

DefenceCollege’sleadershipconcept”DevelopmentalLeadership(DL)”,whichisanewfeatureoftheoperations,aswellasaprogrammeincontractualmattersrelatingtomanagerialresponsibility.Theproportionofmanagers/leaderswhoin2012participatedinsomeformofleadershipdevelopmentprogrammeisapproximately23percent(140managers/leadersofabout600),whichisgenerallythesameproportionasin2011.

Inaddition,anumberofmanagers/leadershaveundergoneworkenvironmentprogrammes.Duringtheyear,adeepeningofthemandatoryworkenvironmenteducationhasbeenintro-ducedwithspecialfocusonpsychosocialworkenvironment.Inadditiontoeducationalprogrammes,leadershipseminarshavealsobeenconducted,aswellaseducationalinitiativestogetherwithotheruniversities.

Work environment and healthIn2012,initiativeswithintheareasofsleep,stressandexhaustionhavebeenprioritisedbasedonKI’s2011employeesurvey.Accordingtothesurveyresults,therewasagroupofapproximatelyfivehundredpeoplewhoexperiencedsleepdisordersseveraltimesaweekduetothenatureoftheirofwork.Initially,ourgoalhasbeentooffertheindividualandworkgrouptoolsandstrategiestocounteractunhealthystress.KI’semployeeshavebeenofferedtheopportunitytoparticipateinsleepschools,workshopsfocusingonearlysignals,andstressmanagement(includingMBSRmethods).

Overall,123employeesparticipatedinaneight-weekprogrammefocusingonsleepandstressmanagement,andcloseto30workgroups(450employees)tookpartinvariousworkshops.

Apilotprojectwasinitiatedin2012underthetitle”Developmentofleadership,teamandindividualresources–Productionofamodeltostrengthentheorganisationalclimateandtheeffectiveutilisationofskills.”Withintheframeworkforthisproject,anindepthmappingoftwodepartmentswasperformedduring2012,whichwillbefollowedbyappropriateinterventionsin2013.

MonitoringofthesystematicworkenvironmentinitiativeswithinKIhasbeenachievedthroughmeetingsinautumn2012involvingallthedepartmentalworkenvironmentgroups.Reportsandplanningofnecessaryinterventionswilltakeplace

inthebeginningof2013.KI’scentralWorkEnvironmentCommitteehasbegunworktodevelopanewguidelineregar-dingworkenvironmentandhealth,whichwillreplaceKI’searlierworkenvironmentpolicy.Thiswillbeimplementedduring2013.KIcoordinateswithPreviawithintheareaofcompanyhealth-care.Intermsofcost,Previa’sinitiativesduringtheyearcanbebrokendownintothefollowing;3percentforpromotionalinitiatives,57percentforpreventativeinitiatives,and40percentforrehabilitationwork.Asanewservice,PreviahasalsointroducedaspecificmanagementsupportinitiativewithinKI.

A new health promotion organisationBasedonguidelinesinaccordancewiththeWHOandNICE(NationalInstituteforHealthandClinicalExcellence,England),KI’smanagementdecidedonanewhealthpromotionorganisationon29Octoberasaclearsignalvalueandasanimportantpartoftheworkwithcreatinganattractiveworkplace.Themainfeaturesofthisneworganisationincludeahealthpromotionreimbursementforallemployees,opportunitiesforworkplace-basedtrainingforstaffandstudents,andcontinuedtargetedhealthpromotioneffortsthroughoutKI.

Visiting Researcher ServicesVisitingResearcherServicesprovidesinformationforin-cominginternationaldoctoralstudentsandresearchers,aswellassupportforstaffatthehostdepartments.During2012,fourintroductiondayswerearrangedfornewcomersandaseminarwasorganisedfordepartmentstaffincollaborationwiththeSwedishMigrationBoardandTaxAgency.Throughthisservice,theopportunityforincomingdoctoralstudentsandvisitingresearcherstounderstandauthorityregulationscanberealised,alongwithprovidingthemanintroductiontolifeinSwedenandatKI.

Participation and influenceDuringtheautumn,some40headsofadministrationandHRmanagersatKIreceivedaneducationintheEmploymentCo-determinationintheWorkplaceActandcollaboration.ThiseducationwasconductedtogetherwiththeSwedishAgencyforGovernmentEmployers.

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56 Karolinska Institutet Annual Report 2012

Infrastructure

Duringtheyear,KIhascontinueditsworkontheestablishedstrategyaimedatcreatinganinternationallyeffectiveinfra-structurewithintheareasofresearchlaboratories,learningenvironments,laboratoryanimalfacilities,biobanks,genomic/proteomicplatformsandinformatics.Planning,whichprimarilyimpactsCampusSolna,hastakenplaceincloseassociationwithStockholmCountyCouncil.TheinvestmentswillbebasedonKI’sownneedsbutwillsimultaneouslysupportthevisionthatKIshareswithmanystakeholders,whichistostrengthenStockholmasaworld-leadinglifesciencecluster.

Duringtheyear,anumberofmajorconstructionprojectsenteredthefinalstage,andthesebuildingsareexpectedtobecomeoperationalin2013.TheseincludeKI’snewauditorium,theWiderströmBuilding,andthethirdhouse,Gamma,withinthecomplexcalledKISciencePark.TheneedfornewpremiseshasbeenaccentuatedduringtheyearasaresultofincreasedactivitiesandexpansionoftheScienceforLifeLaboratory.Untilthenextmajorbuildingcomplex,Biomedicum,isestablishedin2018,KIisgoingtoexperienceaverystrainedpremisessituation.Thenewbuildingsthatwillbecompletedin2013arealreadyfullyleased.

Thestrategicinvestmentinvolvingthemodernisationandexpansionoflaboratoryanimalfacilities,whoseplanningbeganthreeyearsago,isalsointhefinalstageofitsfirstphase.On1January2012,KItookovertheprimatefacilityAstridFagraeus

LaboratoryfromtheSwedishInstituteforCommunicableDiseaseControl,andananimalhousecalledWbergwasalsoopenedattheendoftheyear.Asaresult,KIhasbeenabletoincreaseitscapacitysignificantly.Theprospectsforconductingresearchwithlaboratoryanimalshavethusincreasedwithregardtobothmodernrequirementsfromauthoritiesandbeingabletocatertothehealthofbothlaboratoryanimalsandstaff.Withtheseinvestments,KIwillhaveaccesstobiologicalmodelsthatmodernmedicalresearchwillinevitablydemand.Thesefacilitiesareconsideredstateoftheartwithinthefield.SciLifeLabwillsoonbecreatingaplatformfor,amongotherthings,genomicsandproteomics,thatwillbeabletocompetewiththebestintheworld,evenifthecapacityisnotaslargeassomeinternationalcounterparts.ItwillconstituteanationalfacilitywithitsbaseinStockholm–Uppsala.Thetechnicalplatformnowrequiresstrongerintegrationwith,forexample,researchwithinthefieldsofmedicineandenvironment.

Thestrategicworkiscurrentlyfocusedontwooftheinfra-structuresnecessaryforresearch;biobanksandinformatics.Withinthebiobankarea,thecontinuedexpansionofinfra-structureforsamplestakenintheframeworkofresearchprojectshasbeenunderway,whileanintegratedapproachtoabroadercollectionofhealthcaresamplesforfutureresearchisnotyetinplace.Duringtheyear,ajointworkgrouphasbeenformedforinformaticsissues.

Strategy

Infrastructure

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Karolinska Institutet Annual Report 2012 57

Infrastructure

Premises

KI’s auditoriumInconjunctionwithKI’s200thanniversary,KIreceivedadonationfromtheErling-PerssonFamilyFoundation.Thedonationpertainstoanewauditoriumwith1,000seats,officeandconferencepremises,arestaurantandaFacultyclub.In2012,theexteriorofthebuildingwascompletedandtheconstruction’sspectacularformandfacadeemerged.ThebuildingisexpectedtobereadyinJune2013.

Learning environmentTheFutureLearningEnvironmentsprojectisacollaborativeventurebetweenKIandSCCwhichhasdevelopeddifferenttypesofenvironment,bothinformalandformal,withfuturelearningenvironmentsinmind.In2012,twooftheseinformalenvironmentshavebeenrealisedinSolnaandHuddinge.KIhasalsocommencedtheimplementationofformalenvironmentsintheformofninesmallerandmedium-sizedlecturehalls.

The Widerström BuildingDuringtheyear,abuildingforPublicHealthScienceswaserec-tedonCampusSolna,containinglearningenvironmentsandof-fices.Thepremiseswillenterintooperationinthestartof2013.Withinthebuilding,KIwillbesharingpremiseswithSCCandtheSwedishInstituteforCommunicableDiseaseControl.KarolinskaInstitutetSciencePark(KISP)

TheScienceParkconsistsofthreebuildings;Alpha,BetaandGamma.ThemostsignificantoperationaladaptionshavebeenimplementedinAlfainpreparingsuitablepremisesfortheScienceforLifeLaboratory.BetaisbeingleasedforresearchbySwedishOrphanBiovitrum(SOBI).Theconstructionofthelastbuilding,Gamma,ison-going.TenantswillincludetheScienceforLifeLaboratoryandKISP,whoseappropriationofthepremisesisplannedintwophasesduring2013.

Biomedicum – KI’s new high-tech laboratory for experimental researchIn2012,theBiomedicumprojecthasinvolvedagreatdealofplanningandsigningofagreements,andisnowawaitingthegovernment’sapprovalofthelease.Biomedicumcomprisestwoblocks;alaboratorybuildingandaspeciallaboratoryanimalfacility.Overall,theprojectencompassesapproximately78,000squaremetersandacompletiondateisestimatedfor2018.

Wberg animal house PhaseoneintheWbergproject,therenovationoftheoldWallenberglaboratory,wascompletedandreadyformovinginattheturnoftheyear2012/13.Thesecondphase,theupdatingofcurrentanimalfacilities,isestimatedtobecompletebymid-2013.

KI’s portfolio of premises and costs

YearArea sq.m.

(MUA)Cost (SEK m.) Percentage of

total costs

2009 198,009 553 12

2010 204,494 565 11

2011 200,859 586 11

2012 213,881 667 12

Premises costs include rent, electricity, media and janitorial services, etc.

Source: KI’s property management system and Agresso

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Financial report

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Karolinska Institutet Annual Report 2012 59

Financial report

KarolinskaInstitutet’sturnoverfor2012wasSEK5,646million(SEK5,340million).ApositivechangeincapitalofSEK108millionwasreportedforthefinancialyear.SEK–31.5millionofKI’searningsisattributabletoKI’ssubsidiaryKarolinskaInstitutetHoldingAB.Inthissection,Agressoshouldbeconsideredasthesourceunlessotherwisestated.

RevenueKarolinskaInstitutet’soperatingrevenueroseby5.7percentcomparedwith2011.Duringtheperiod2009–2012,thetotalincreaseinoperatingrevenuewasSEK766millionor15.7percent.

Direct government fundingTheincreaseinfunding(excludingfundingformedicaltrainingandresearch)fortheyearwasSEK129million,or6.9percentcomparedwith2011.Ofthepreviousyears’fundingsavingswithinfirst-cycleandsecond-cycleeducation,SEK11.2millionhasbeenreturned.ThisisbecauseKIexceededthe’fundingcap’atsettlementofFTEstudentsandAPEs.KIhadSEK49.8mil-lionremaininginfundingsavingsattheendof2012–seealsofundingreportandNote1.Theincreaseinallocationoffundsforresearchanddoctoraleducation,SEK105.6million,isattributabletoinvestmentswithinstrategicresearch,quality

relatedallocationandpriceandsalaryconversion(0.9percent).CooperationwithintheframeworkofthemedicaltrainingandresearchagreementisreportedunderthesectionCollabo-ration.

External funding, fees and grantsIn2012,externalrevenuefromfeesandgrantsrosebySEK186millioncomparedwith2011.Duringtheyear,anumberofexternalprojectswerecompleted,whichimpactedrevenuefavourably.ThecompletedassignmentfromStockholmCountyCouncilregardingKarolinskaInstitutet’sSchoolofPublicHealthisanexample.

FinancingforthetakeoverofoperationsfromtheSwedishInstituteforCommunicableDiseaseControlhasbeenreceivedasgrantfundingin2012.In2013,thesefundswillbereceivedasgovernmentfunding.

Financial FinancialrevenueamountedtoSEK55millionin2012.Thebig-gestindividualitemunderrevenuewasSEK47.0million(SEK55.3million)ininterestrevenueontheinterestaccountwiththeSwedishNationalDebtOffice.Theannualaverageinterestrateontheinterestaccountfor2012was1.47percent(1.78percent).

Revenue, SEK millions

2009 2010 2011 2012

Education and research funding 1,535 1,765 1,861 1,990

Clinical education and research funding 550 570 575 576

Total funding 2,085 2,335 2,436 2,566

External funding, fees and grants 2,770 2,888 2,839 3,025

Financial 25 29 66 55

Total external funding 2,795 2,918 2,905 3,080

Total revenue 4,880 5,253 5,340 5,646

Funding/Total revenue 43% 44% 46% 45%

External funding/Total revenue 57% 56% 54% 55%

A correction of SEK 30.3 million has been made to the 2011 external funding on account of a modified accounting principle for doctors with combined positions. See Note 2.

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60 Karolinska Institutet Annual Report 2012

Financial report

Financing diagram KI’s revenue is divided up by financing category in the following chart. The largest individual external sources of funding are listed in the appendix, Table 11.

Karolinska Institutet’s revenue for 2012, SEK 5,646 million in total (2011, SEK 5,340 million)

Government funding

45% (46%)

Research councils 13% (12%)

Other government agencies 7% (6%)

Swedish foundations & organisations 13% (13%)

Foreign foundations & organisations 6% (6%)

Swedish companies 4% (4%)

Foreign companies 1% (2%)

Municipalities & county councils

10% (10%)

Financial revenue 1% (1%)

Theincreaseincostsin2012was6.1percentcomparedwiththepreviousyear.Duringtheperiod2009–2012,KI’scostshaverisenbySEK772million,or16.3percent.

StaffStaffcostsincreasedbySEK118millionor4.3percentcomparedwiththepreviousyear.InOctober2012,KIhad4,768employees,anincreaseof65whencomparedwiththesameperiodin2011.Asalaryreviewhasbeenenteredintothebookson1October2012withanestimatedaverageincreaseof2.8percentforthelastthreemonthsoftheyear.

PremisesAttheendoftheyear,KI’spremisesportfoliototalled213,881m².PremisescostsroseintotalbyapproximatelySEK81millioncomparedwith2011.Inadditiontoindexincreasesforrent,theincreaseincostswasduetoexpandedactivitiesincludingtheScienceforLifeLaboratoryandthetakeoverofoperationssuchastheAstridFagraeusLaboratory.Renovationsofexistingpremisesalsoimpactedpremisescostsastheyarereportedasadditionalrent.

Other operationsOtheroperatingcostsrosebySEK124millioncomparedwith2011,andrepresentanequalpercentageofthecostsasin2011.

FinancialFinancialcostsfellbySEK20millioncomparedwith2011.Thisreductionislargelyduetolowercostsrelatingtoexchangelossesonthesaleofsecurities,SEK1.2million(SEK15.6million).Themarketvalueoftheshareportfoliohasexceededtheoriginalbookvaluein2012,whichledtothe2011write-downoffinancialsecuritiesofSEK1.5millionbeingreversedbythesameamount.InterestexpensesonloansintheSwedishNationalDebtOfficehavedecreasedduetoloweraverageinterestratesin2012,1.47percent(1.78percent).

Costs

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Karolinska Institutet Annual Report 2012 61

Financial report

Therevenuestatementfortheyearisbrokendownbybusinessareainaccordancewiththetablebelow.Thepositivechangeincapital,SEK108million(144.5million),relatesmostlytoresearchandthird-cycleeducation,SEK150.9million.KI’sassetmanagementisalsoreportedwithinthis.Thechangeincapitalhasarisenprimarilywithingovernmentfunding-financedresearchandcanbetracedtothemajorinvestmentmadeinthelatestResearchBill.Thedelayinusingtheinvestedfundsalsoexplainsthepositivechangeincapitalfortheyear.Itcannowbenotedthatoperationsaregrowingatafasterratethanpreviously,whichconstitutesamorerapidutilisationof

funding.Externalgrant-financedandcontract-financedprojectsthathavebeenconcludedduringtheyear,andwhichhavefundsremaining,aretakenupasrevenueduringtheyearandhaveapositiveimpactonthechangeincapital.Negativechangeincapitalwithinfirst-andsecond-cycleeducation,SEK11.4million,istracedtothefactthataccumulatedequityisusedtofinancetheyear’sactivities.KI’ssubsidiary,KarolinskaInstitutetHoldingAB,reportedalossofSEK31.5million.Thisamountconsistsofthe2012preliminaryresultsandadjustedfixedincomefor2011.

Change in capital

Cost trend, SEK millions

2009 % 2010 % 2011 % 2012 %

Staff 2,495 53 2,606 52 2,753 53 2,871 52

Premises 553 12 565 11 586 11 667 12

Other operations 1,555 33 1,659 33 1,645 32 1,769 32

Financial -13 0 8 0 29 1 9 0

Depreciation 144 3 158 3 175 3 190 3

Total costs 4,734 4,994 5,188 5,506

A correction of SEK 30.3 million has been made to the 2011 staff costs on account of a modified accounting principle for doctors with combined positions. See Note 5.

Revenue statement by business area 2012, SEK millions

TotalBachelor’s (first-cycle) and Master’s

(second-cycle) educationResearch and doctoral

(third-cycle) education

Revenue

Direct government funding 2,565.5 833.1 1,732.4

Fees and other remuneration 770.7 100.6 670.1

Grants 2,254.4 19.8 2,234.6

Financial 54.9 0.00 54.9

Total revenue 5,645.6 953.6 4,692.0

Costs

Staff 2,871.2 507.7 2,363.5

Premises 666.9 109.2 557.7

Other operations 1,768.9 335.7 1,433.2

Financial 9.0 0.1 8.9

Depreciation 190.0 12.2 177.8

Total costs 5,506.1 965.0 4,541.1

Change in capital for the year (excluding subsidiaries and revenue collection)

139.5 -11.4 150.9

Results from participations in subsidiaries and associated companies

-31.5

Results from revenue collection operations 0.0

Change in capital for the year (including subsidiaries and revenue collection)

108.0

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62 Karolinska Institutet Annual Report 2012

Financial report

ThepositivechangeincapitalfortheyearforKI’sordinaryoperationsishigherthantheforecastcontainedintheinterimreport.ThebiggestdeviationintermsofrevenueistheitemExternalfunding,feesandgrants.Thedeviationismainlyduetorevenuefromprojectstakenupasincomebeinghigherthanestimatedintheinterimreport.

Theyear’sstaffcostswereslightlylowerthanexpected,explainedbythereducednumberofemployeesthanhadbeenforecast.

Premisescostswerehigherthanexpectedmainlyduetothemajorinfrastructuralinvestmentscurrentlyunderway,whereinitcanbedifficulttoaccuratelypredictcosts.

Theoutcomeforotheroperationsisprimarilyduetoagreaterincreaseinpurchasedservicesthanexpected.

Advances from external sources of funding and liquid assetsUnexpendedgrantsanddeferredcontractrevenuerelatetonon-accruedcostsforactivitieswhereremunerationispaidinadvancebythefinanciers.CompletedexternalprojectsmeanthattheitemDeferredcontractrevenuedecreases,whichisreflectedinincreasedrevenueintherevenuestatement.

Accruedgrants/contractsrelatestoaccruedcostsforgrant-financedandcontract-financedactivities,whereremunerationisreceivedafterwardsandwhereagreements/contractsexisttoconfirmthis.

Thetableshowsthetrendforadvancesfromgrants/contracts,reducedbyon-goingworkwhichisinvoiced/orderedafterwardsandliquidassets.

Comments on the differences between outcome and forecast

Revenue statement 2012, SEK millions

Outcome Forecast Difference

Revenue

Direct government funding 2,566 2,566

External funding, fees and grants 3,025 2,943

Financial 55 60

Total revenue 5,646 5,569 77

Costs

Staff 2,871 2,905

Premises 667 640

Other operations 1,769 1,730

Financial 9 11

Depreciation 190 186

Total costs 5,506 5,472 34

Change in capital 140 97 43

Advances and liquid assets, SEK millions

2009 2010 2011 2012

Unexpended grants 2,030 2,224 2,277 2,313

Deferred contract revenue 333 362 358 294

Accrued grants -168 -216 -205 -208

Accrued contracts -6 -4 -9 -8

Net advances 2,189 2,366 2,421 2,391

Liquid assets, bank and Swedish National Debt Office 2,550 3,064 3,384 3,388

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Karolinska Institutet Annual Report 2012 63

Financial report

KarolinskaInstitutetadministersindividualdonationsintendedformedicalscienceatKI.Donationsaredividedupinto:1. FundsreportedwithinKIasanauthority.2. Independentfoundationsthataretheirownlegalentities, withadministrationlinkedtoKI.Forfunds,whichareadministeredandreportedwithinKI,

boththereturnandthecapitalmaybeused.Thefoundationsareseparatelegalentities,andissuetheirownseparateannualreports.Thefoundations’distributedreturntoKIisincludedasexternalgrantsinKI’sreporting.ThefoundationsarereportedinsummarybelowtogiveafullpictureofKI’sdonationcapital,regardlessofthelegalform.

Asset management

Paid research grants In2012,paidresearchgrantsincreasedbySEK143millioncomparedwith2011.GrantfundsfromtheSwedishResearchCouncilincreasedbySEK60millioncomparedto2011.

ThetakeoverofoperationsfromtheSwedishInstituteforCommunicableDiseaseControlhasimpactedgrantfundingpositivelybySEK33million.Thisfundingwillbereceivedasdirectgovernmentfundingfrom2013.GrantfundingfromPerssonFamilyFoundationsincreasedbySEK29million.

Administrative capitalTheaccumulatedadministrativecapitalincludingchangeincapitalfortheyearisSEK1,288.6million,dividedupasfollows:

• SubsidiariesSEK55.5million• AssetmanagementSEK30.2million• OrdinaryoperationsSEK1,202.9million

SeeNotes10and24.

Growth of invested funds during 2012Attheendoftheyear,themarketvalueofsharefundsandinte-rest-bearingfundsreportedwithinKI’sfundmanagementstoodatSEK259.0million(SEK272.4million).During2012,thenetoutflow(differencebetweenpurchasedandsoldfunds)wasminusSEK28.6millionandthechangeinvaluewasplusSEK16million.Managedinvestmentfundportfoliosarein-vestedupto49.3percentinmutualfundsinSwedenandothercountries,and41.1percentinSwedishinterest-bearingassets.Alternativeinvestmentsaccountfor9.6percentoftheportfolio.Return

Thetotalreturnontheinvestmentfundportfoliowas+6.4percentin2012,whichis0.5percentagepointslowerwhencomparedtothereferenceindex.

Funds

Reference index for total administration 2012

SinceOctober2012,thecompositionofthereferenceindexhasbeen:Swedishinterest-bearing OMRXBond 40Shares MSCIWorldNDR (expressedinSEK) 50Alternativeinvestments SSVX12M +3percentagepoints (yearoveryear) 10

DuringJanuary–September2012,theproportionofalternativeinvestmentswaslower:Swedishinterest-bearing OMRXBond 40Shares MSCIWorldNDR (expressedinSEK) 55Alternativeinvestments SSVX12M +3percentagepoints (yearoveryear) 5

Paid research grants, SEK millions

2009 2010 2011 2012

Research grants 2,284 2,236 2,207 2,350

Return in per cent compared with the reference index

2009 2010 2011 2012

KI’s funds 14.9 1.9 -3.8 6.4

Reference index 13.3 4.1 0.9 6.9

Return is stated net, i.e. including dividends and deductions for administrative costs. Share indices are stated inclusive of reinvested dividends.

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64 Karolinska Institutet Annual Report 2012

Financial report

Distribution of the investment fund portfolio, 31/12/2012

Cash 2,7%

Interest-bearing securities 38,4%

Alternative investments 9,6%

Swedish share funds10%

Global share index funds 39,3%

Thereare235associatedfoundationsoutsideofKI’sscopeofrfeporting,theseissueseparateannualaccountsandannualreports.Nonewfoundationswereestablishedduring2012.NewdonationsplacedwithexistingfoundationstotallingSEK13.7millionwerereceived.Incomparisonwith2011,netwealthhasincreasedbySEK69million,or5.9percent,afterdividendsbutincludingnewdonations.Attheendoftheyear,foundationfundsconsistedofSwedishshares22percent(31),foreignshares41percent(38),hedgefunds8percent(4),interest-bearingsecurities27percent(24)andliquidassets2percent(3).Throughouttheyear,SEK35.8millionwasdistributedtoKIfromthefoundations.Itistheindividualpurposeofeach

foundationthatgovernstheaimandemphasisofthegrant.ForfoundationswithadministrationlinkedtoKI,KIhasreceivedremunerationofSEK0.9millionforadministrativecosts.

Foundations

Distributions from KI’s funds During 2012, SEK 55.8 million was distributed internally at KI. This is divided up by purpose in accordance with the table below.

Allocations from KI’s funds, SEK millions

2009 2010 2011 2012

Research 36.2 32.6 45.4 35.7

First-level education 0.8 0.9 1.1 0.1

Other 20.0 20.0 20.0 20.0

Total 57.0 53.5 66.5 55.8

Research purpose Donor Amount, SEK millions

Donation Professorship in medical science and in clinical medical research T&R Söderberg Foundation 33.0

Medical research and doctoral education Foundation of Tyra and Gustav Svensson’s Memory 16.9

Young gifted researchers W.K. Bowes Foundation 5.3

Cognitive neuroscience Jochnick Foundation 5.0

Scholarships to students from non-EU countries Friends of Karolinska Institutet 4.5

Cancer research Sune and Charlotta Hays Foundation 3.4

Research within haematology Dr Åke Olsson’s Foundation 2.6

Medical research, preferably rheumatic diseases, heart disease and cancer Ulla and Karl Svanlund’s Foundation 2.0

Uppdrag Besegra Stroke (Mission Conquer Stroke) Swedish Heart-Lung Foundation 2.0

Incoming funds to asset managementIn 2012, KI received paid funds to asset management of SEK 90.9 million (85.9). Individual donations of SEK 2 million or more are reported to the right..

Foundations, SEK million

2009 2010 2011 2012

Net wealth 1,231 1,244 1,166 1,235

Funding granted* 52.8 47.5 45.1 35.8

*Amounts for 2009–2011 are adjusted with regard to research grants to KI from external foundations. They have previously been erroneously reported here.

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Karolinska Institutet Annual Report 2012 65

Financial report

Revenue statement, SEK thousands

Outcome Outcome

01/01/2012 01/01/2011

31/12/2012 31/12/2011

Revenue from operations

Revenue from funding (Note 1) 2,565,547 2,435,581

Revenue from fees and other remuneration (Note 2) 770,747 740,940

Revenue from grants (Note 3) 2,254,418 2,098,274

Financial revenue (Note 4) 54,902 65,662

Total revenue 5,645,615 5,340,456

Operating costs

Staff costs (Note 5) -2,871,225 -2,753,350

Premises costs (Note 6) -666,949 -585,653

Other operating costs (Note 7) -1,768,913 -1,644,846

Financial costs (Note 8) -9,010 -28,665

Depreciation and write-downs (Notes 11-13) -189,991 -175,106

Total costs -5,506,088 -5,187,621

Operational outcome 139,527 152,835

Results from shares and participations in wholly-owned

and part-owned companies -31,542 -8,525

Revenue collection operations (Note 9)

Revenue from fees etc. and other revenue not at the disposal of the authority 2,117 2,067

Funding credited to the Government budget from revenue collection operations -2,114 -1,871

Balance 3 196

Transfers

Funding received from the Government budget for financing grants 19,801 20,565

Funding received from the authorities for financing grants 34,745 29,577

Other funding received for financing grants 84,661 82,928

Contributions paid -139,206 -133,071

Balance 0 0

CHANGE IN CAPITAL FOR THE YEAR (Note 10) 107,989 144,506

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66 Karolinska Institutet Annual Report 2012

Financial report

Balance sheet, SEK thousands

ASSETS 31/12/2012 31/12/2011

Intangible fixed assets (Note 11)

Capitalised expenditure for development 3,828 4,457

Rights and other intangible fixed assets 2,972 4,085

Total intangible fixed assets 6,800 8,543

Tangible fixed assets

Improvement expenditure on property owned by others (Note 12) 42,631 61,073

Machinery, equipment, fixtures and fittings, etc. (Note 13) 662,921 605,589

Fixed assets under construction (Note 14) 65,272 31,438

Total tangible fixed assets 770,824 698,101

Financial fixed assets

Shares and participations in wholly-owned and part-owned companies (Note 15) 55,458 102,443

Other long-dated securities holdings (Note 16) 236,251 244,959

Total financial fixed assets 291,709 347,403

Receivables

Accounts receivable 145,359 121,845

Receivables from other authorities (Note 17) 95,014 80,074

Other receivables (Note 18) 303 772

Total receivables 240,676 202,691

Cut-off items

Prepaid expenses (Note 19) 151,478 128,600

Accrued revenue from grants (Note 20) 207,733 204,561

Other accrued revenue (Note 21) 10,512 14,787

Total cut-off items 369,724 347,948

Settlement with the Government

Settlement with the Government (Note 22) -50,130 -90,435

Total settlement with the Government -50,130 -90,435

Cash and bank

Balance of Swedish National Debt Office interest account (Note 23) 3,244,073 3,191,142

Cash, postgiro and bank 143,503 193,232

Total cash and bank 3,387,576 3,384,374

TOTAL ASSETS 5,017,179 4,898,625

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Karolinska Institutet Annual Report 2012 67

Financial report

Balance sheet, SEK thousands

CAPITAL AND LIABILITIES 31/12/2012 31/12/2011

Administrative capital (Notes 10+24)

Government capital 5,238 5,238

Profit participation in wholly-owned and part-owned companies 82,000 96,969

Balanced change in capital 1,093,334 949,303

Change in capital according to the revenue statement 107,989 144,506

Total administrative capital 1,288,561 1,196,016

Provisions

Provisions for pensions and similar obligations (Note 25) 7,438 11,548

Other provisions (Note 26) 39,776 38,013

Total provisions 47,214 49,561

Liabilities etc.

Swedish National Debt Office loans (Note 27) 442,336 400,245

Liabilities to other authorities 105,610 95,777

Accounts payable 247,332 192,978

Other liabilities 137,349 177,032

Total liabilities, etc. 932,627 866,032

Cut-off items

Accrued costs (Note 28) 133,031 139,522

Unexpended grants (Note 29) 2,313,002 2,276,622

Other prepaid revenue (Note 30) 302,743 370,871

Total cut-off items 2,748,777 2,787,016

TOTAL CAPITAL AND LIABILITIES 5,017,179 4,898,625

Contingent liabilities (Note 31) 183,900 None

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68 Karolinska Institutet Annual Report 2012

Financial report

Accounting principles

ThisannualreporthasbeenpreparedinaccordancewiththeSwedishAnnualReportsandBudgetDocumentationOrdinance(2000:605).KarolinskaInstitutetfollowsgenerallyacceptedaccountingprinciplesinaccordancewiththeSwedishNationalFinancialManagementAuthority’sgeneraladviceon§6oftheSwedishBookkeepingOrdinance(2000:606).

Revenueandcostsareperiodisedinaccordancewiththeaccrualsconcept.Thecut-offamountisSEK20,000,000.

ThelimitationamountfordirectdepreciationagainstequityissetatSEK20,000,000.

Valuation of receivables and liabilitiesReceivableshavebeenenteredattheamountwhich,afterindividualexamination,isexpectedtobepaid.Inthosecaseswhereinvoicesorequivalenthavebeenreceivedafterthesetcut-offdate(04/01/2013)orwheretheamountofthereceivableorliabilitywasnotknownexactlywhentheaccountswereproduced,theseamountsarereportedascut-offitems.Foreigncurrencyreceivablesandliabilitieshavebeenvaluedattheexchangerateonthebalancesheetdate.

Valuation of bank balances in foreign currenciesForeigncurrencybankaccountbalanceshavebeenvaluedattheexchangerateonthebalancesheetdate.

DonationsTheacquisitionvalueofadonationisvaluedatthemarketvalueatthetimeofacquisition.Inthecaseofbequeathedgifts,thetimeofacquisitionisdeemedtobethedistributionoftheestate.

Valuation of intangible fixed assetsIntangiblefixedassetsareassetsdevelopedbyKIwhichareintendedtoincreaseKI’sadministrativeservicepotential.Thefinanciallifetimeshallbeatleastthreeyears,andtheacquisi-tionvalueshallbeatleastSEK20,000,000.TheacquisitionvalueincludesbothexternalpurchasesandKI’sowndirectcosts.Installationsaredepreciatedlinearlyatamaximumoffiveyearsfromthemonthofacquisition.

Valuation of tangible fixed assetsAssets,excludingcomputers,whichareintendedforpermanentusewithanacquisitionvalueofatleastSEK20,000,000andhaveanestimatedfinanciallifetimeofthreeyearsorlongeraredefinedasfixedassets.ComputerswithanacquisitionvalueofuptoSEK30,000,000arereportedascostsimmediatelywhentheestimatedfinanciallifetimeislessthanthreeyears.

ObjectswhichconstituteafunctioningunitwithacombinedacquisitionvalueofSEK20,000,000ormoreareclassifiedasfixedassets.Theseassetsarereportedattheiracquisitionvaluelessaccumulateddepreciationaccordingtoplan.Fixedassetsaredepreciatedlinearlyovertheassessedfinanciallifetime.

Depreciationtimesformachinery,equipment,fixturesandfittings,etc.areappliedaccordingtoestimatedlifetimesofthreeyears,fiveyearsortenyears.

Financial fixed assets• Bonds:Onpurchase,thepurchasesumisenteredinthebalancesheetasafinancialasset.Onselling,thefinancialassetsarereducedbythebookvalueandanydifferenceisenteredinthebalancesheetsasacapitalgainoracapitalloss.• Shares/participations:Onpurchase,thepurchasesumisenteredinthebalancesheetasafinancialasset.Onselling,thefinancialassetsarereducedbythebookvalueandthedifferenceisenteredinthebalancesheetsasacapitalgainoracapitalloss.• Depreciation and appreciation:Ifthetotalmarketvalueoftheportfolioisconsiderablylessthanthebookvalueanditisnotcertainwhetherthisdecreaseispermanent,adepreciationisperformed.Adepreciationisenteredbyreducingfinancialassetsinthebalancesheetagainstanincreaseinfinancialcostsintherevenuestatement.Depreciationsandappreciationsarereversedbydecreasingorincreasingfinancialcostswhenthemarketvaluerises.

Externally financed operationsWhenperiodisinggrantsorfees,therevenuefortheperiodisdeterminedbythecostsfortheperiod.Surplusgrantrevenueorfeerevenueisperiodisedasunexpendedgrants/feesorotherprepaidrevenue.

Unexpendedrevenuethatarenotgrantsorfeesistakenupasrevenueagainstthechangeincapitalfortheyear.

Forprojectswherepaymentisreceivedafterwardsandwherethisisconfirmedbyanagreement/contract,thecostsareperiodisedagainstotheraccruedrevenue(inthecaseoffeefinancing)orasaccruedgrantrevenue(inthecaseofgrantfinancing).Ifthereisnoagreement/contract,thecostsaretakenupasrevenueandaffectthechangeincapitalfortheyear.

Karolinska Institutet Holding ABOn1January1998,KarolinskaInstitutettookovertheadministrationofKarolinskaInstitutetHoldingABfromtheMinistryofIndustryandCommerce.Intheannualreport,detailsofparticipationsinsubsidiariesarereportedasshareinearningsinaccordancewiththeequitymethod.TheholdingisreportedinthebalancesheetundertheitemsParticipationsinsubsidiaries,GovernmentcapitalandProfitparticipationinsubsidiaries.

ImprovementexpenditureonpropertyownedbyothersImprovementexpenditureonpropertyownedbyothersistreatedasadirectcostwhenitamountstoamaximumofSEK500,000.Investmentstotallingahigheramountwillbedealtwithviarentsurcharges.

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Karolinska Institutet Annual Report 2012 69

Financial report

Reporting of combined positionsIn2012,KIchangedaccountingprinciplesforSPVpremiumswhichapplytodoctorsholdingcombinedpositions(doctorswhoseservicesaresharedbetweenKarolinskaInstitutetandStockholmCountyCouncil,SCC),inaccordancewithdirectivesfromtheSwedishNationalFinancialManagementAuthority(ESV).Thereasonforthechangeinaccountingprincipleswasbecause,asof2011,thepensionpremiumsareincludedinthecounterpartyreportingwithSPV.Previously,KIpostedSPVpremiumstoSCCasannon-governmentaltaxexemptallowance.TheamendmentaffectstheitemOtherrevenuefromfeesandremunerationthathasbeenreduced,seeNote2.In2012,SCC’spensionpremiumswerereportedasacostreductionwhichaffectstheitemEmployerfees,pensionpre-miumsandotherfeesinaccordancewithlawsandagreements,seeNote5.Correctionstothe2011figuresaremadeintherevenuestate-mentandrelatednotes,aswellasthefinancialtables.Exemptionfromcertainprovisionsforuniversitiesandhighereducationinstitutionsinaccordancewiththepublicserviceagreement

Universitiesandhighereducationinstitutionsaregrantedexemptionfromtheprovisiononsettlementoffundinginaccordancewith§§5and16oftheSwedishAppropriationOrdinance(1996:1189).Settlementagainstfundingandfundingitemsforfundspaidouttotheeducationalinstitution’sSwedishNationalDebtOfficeinterestaccountshalltakeplaceinconnectionwiththemonthlypaymentstotherelevanteducationalinstitution’sSwedishNationalDebtOfficeinterestaccount.

Universitiesandhighereducationinstitutionsaregracctedexemptionfrom§11oftheSwedishAppropriationOrdinance(1996:1189)insuchawaythattheeducationalinstitutionmaytransferbothsurplusproductionandunusedfundingcaps(fundingsaving)toamaximumvalueoftenpercentofthefundingcaptothesubsequentbudgetyear,withoutspecifically

requestingthegovernment’sconsent.Universitiesandhighereducationinstitutionsaregrantedexemptionfromtheprovisionsofchapter2,§4,paragraphthreeoftheSwedishAnnualReportsandBudgetDocumentationOrdinance(2000:605)thattheannualreportmustincludeanaccountofkeyratios.UniversitiesandhighereducationinstitutionsmustinsteadprovideinformationinaccordancewithAppendix6.

Universitiesandhighereducationinstitutionsaregrantedexemptionfromtheprovisionsofchapter2,§4oftheSwedishAnnualReportsandBudgetDocumentationOrdinance(2000:605)toproduceandsubmittothegovernmentafundsstatementintheannualreport.

InformationInaccordancewiththeSwedishNationalFinancialManagementAuthority’sguidanceonmulti-financedoperations(ESV2006:28),allsourcesoffinancingshouldbeusedinparallel.Oneofthereasonsforthisistogiveanaccuratepictureofhowtheresourcesareused.KIhassignificantsourcesofexternalfinancing,particularlyforgrant-financedresearch,wherefundinghasbeenappliedforandgrantedforresearchwithinaspecificsubject.Grantedfundingissubjecttoconditionsinaccordancewithagreements,andmustbeusedinaccordancewiththeplandecidedonintheagreement.Grantfundingreceivedisnotdirectlylinkedtoperformance,butislinkedtothecostsresearchersappliedforinordertocarryoutresearchwithinaspecificsubject.Againstthisbackground,KIdoesnotfullyapplyparallelconsumptionsincegrantsareusuallygrantedforspecificcostsandnotforperformance.

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70 Karolinska Institutet Annual Report 2012

Financial report

Accounting against funding and revenue headings (SEK thousands)

ACCOUNTING AGAINST REVENUE HEADINGS

Revenue heading Revenue

2,542,001 Patient fees for dentistry education 2,114

2394,01 Interest revenue 0

Total 2,114

CHARGEABLE ACTIVITIES WHERE REVENUE IS NOT AT KI’S DISPOSAL

Activity

Surplus/deficit until

2010

Surplus/deficit until

2011 Budget Outcome Budget Outcome

Surplus/deficit

2012

Closing surplus/

deficit 2012

Dental care centre

Patient fees -309 196 2,000 2,117 2,000 2,114 3 199

REVENUE 2012 COSTS 2012

16.2:15 First-level (first- andsecond- cycle) education(framework)

16.2:15 1 Funding cap* 89,805 589,150 0 -28,812 650,143 600,358 49,785

16.2:16 Research and doctoral (third-cycle) education (framework) 0

16.2:16 2 Basic resource 0 1,307,185 1,307,185 1,307,185 0

16.2:71 Special mandate for universities and higher education institutions

16.2:71 17 Dental care centre 0 92,640 92,640 92,640 0

16.2:71 18 Test after doctors' period of practice following medical school

0 4,468 4,468 4,468 0

Total 0 97,108 0 0 97,108 97,108 0

16.2:72 Remuneration for clinical education and research

0

16.2:72 6 Karolinska Institutet 574,400 327 574,727 574,727 0

16.2:72 9 Task of developing clinical education and research 0

5,9705,970

5,9700

16.2:55 11 Further education of nursing staff* 327 0 -327 0 0 0

Total 327 580,370

0

580,697 580,697 0

Total 90,132 2,573,813 0 -28,812 2,635,133 2,585,348 49,785

*) Since 2010, there are two discrepancies with the Government report in Hermes regarding the opening transfer amount and the withdrawal amount. The discrepancy is SEK +428 thousand for 16.2:15.1, which corrects itself in the withdrawal of SEK 28,812 thousand. For 16.2:55 11, the discrepancy is SEK -16 thousand, which has been adjusted payment-wise during the year. This table shows the adjustment of the opening transfer amount in accordance with ESV’s instructions. Pursuant to this, data is consistent with Hermes regarding the closing transfer amount.

Openingtransferamount

Allocation for the yearin accordancewith public service agreement

Re- allocated amount

With-drawal

Total avaliable amount

Expend-iture

Closingtransferamount

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Karolinska Institutet Annual Report 2012 71

Notes

Note 1. Revenue from funding31/12/2012 31/12/2011

Bachelor’s (first-cycle) and Master’s (second-cycle) education 697,466 675,539

Research and doctoral (third-cycle) education 1,291,751 1,185,376

Remuneration for clinical education and research 576,330 574,666

2,565,547 2,435,581

NOTES (SEK THOUSANDS)

A. Available funds (including agreed additional budget) Funding cap for the year 589,150

+ any included funding saving 60,993 Total (A) 650,143

B. Total outcome for first- and second-cycle education

Remuneration for APEs from December in the previous budget year 1,400

Outcome total remuneration in accordance with table 1 598,958

+ any use of previous surplus production 0

Total (B) 600,358 Total (A-B) 1 49,7851 Positive total transferred to table of funding saving below. Negative total transferred to table of surplus production below.

Table. Funding saving

Total closing funding saving (A-B) 49,785

– any funding saving above 10% of the funding cap 2

Closing funding saving 49,785

Table. Surplus production

Total closing surplus production

– any surplus production above 10% of the funding cap 2

Closing surplus production 0

2 The portion of the funding saving and surplus production that the educational institution may not retain without the Government’s approval.

Table 2aCalculation of funding savings and surplus production (SEK thousands)

Funding cap (SEK thousands) 589,150The report shows that the educational institution exceeds the funding cap by (SEK thousands) 9,808The report shows that the educational institution is below the funding cap by (SEK thousands) 0

Table 1aReport of the number of full-time students (FTSs) and annual performance equivalents (APEs)Outcome in relation to the period 01/01/2011 to 31/12/2011

EDUCATION AREA Outcome FTE Outcome APE FTE remuneration (SEK thousands)

APE remuneration(SEK thousands)

Outcome totalremuneration

Humanities 28 26 665 499 1,164Social sciences 517 472 12,120 9,028 21,147Natural sciences 425 383 21,278 16,193 37,471Technology 133 114 6,677 4,819 11,495Care 1,792 1,624 95,412 74,920 170,332Odontology 437 395 19,242 20,282 39,525Medicine 2,553 2,292 151,927 165,896 317,823

Total 5,885 5,307 307,321 291,637 598,958

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72 Karolinska Institutet Annual Report 2012

Notes

31/12/2012 31/12/2011

Revenue from fees and remuneration in accordance with§ 4 of the Swedish Fees Ordinance 82,791 63,024

Other revenue from fees and remuneration 687,956 677,916

770,747 740,940

Other revenue from fees and remuneration consists primarily of contract revenue.

Note 2. Revenue from fees and other remuneration

The increase in § 4 revenue is due to increased rental income and increased tuition fees for students from third countries. The item Other revenue from fees and remuneration for 2011 has been revised due to changes in accounting principles in 2012 regarding SPV premiums for doctors holding combined positions. These are reported as a cost reduction under Staff costs, also see Note 5.

Chargeable activities where revenue is at KI’s disposal, SEK thousandThe accumulated surplus of chargeable activities amounts to SEK 95,393 thousand, which represents 18.6 per cent of the operation’s turnover of SEK 514,137 thousand. Part of the surplus will be used in the context of enhanced cooperation with SCC within Public Health Sciences. It will also be used for the co-financing of projects where full cost coverage is not achieved. The surplus will be used, for example, in the development of new courses within the framework of contract education.

Activity

Surplus/deficit

until 2010

Surplus/deficit

2011Revenue

2012Costs 2012

Surplus/deficit 2012

Accumulated closing

surplus/deficit2012

First-or second-cycle education

Commissioned education 4,417 225 6,925 8,593 -1,668 2,974

Vocational college, KY, etc.

Contract education 9,113 43 63,146 52,273 10,873 20,029

Education for students who are obliged to pay tuition fees -1,479 -1,937 5,724 5,895 -171 -3,587

Sum 12,051 -1,669 75,795 66,760 9,034 19,416

Research and third-cycle education

Contract research 53,704 330 395,270 373,063 22,207 76,241

Sum 53,704 330 395,270 373,063 22,207 76,241

Activities where full cost coverage requirements do not apply

Swedish Scholastic Aptitude TestsLetting apartments 1

- exchange programmes and visiting researchers 0 0 339 339 0 0

Letting apartments 1

- Government Decision (U2010/4277/UH)Optician centre 76 -95 453 698 -245 -264

Other activities in accor-dance with Appendix 4 2 42,280 42,280

Sum 76 -95 43,072 43,317 -245 -264

Notes, see opposite side.

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Karolinska Institutet Annual Report 2012 73

Notes

¹ Karolinska Institutet does not deal with the actual letting of accommodation for international students and visiting researchers, but procures this as a service from Karolinska Institutet Housing AB (formerly University Accommodation Center AB,UAC), a wholly-owned company within KI Holding AB. KI paid a fee of SEK 3,492,000 for this during 2012 (SEK 3,000,000/year for 2010 and 2011). In addition, KI has had miscellaneous costs of SEK 261,000 (SEK 257,000). These costs are paid for by funding. Since letting takes place in this way, it is not classified in KI’s accounts as fee-financed activities. KI Housing makes 277 (271) apartments available to KI, of which 64 (58) are researcher apartments and 213 (213) are student rooms. In total, KI Housing rented out apart-ments/rooms to 808 (816) international students and visiting researchers during 2012 (the reservation system was replaced in Jan-Feb, which is why an estimate has been made for this period). The occupancy rate was around 88 per cent. In addition, KI rented out accommodation during 2012 for visiting researchers for a total of SEK 339,000 (SEK 216,000). The cost is assessed to be the same. The need for apartments/rooms is expected to increase in line with increased international exchanges and cooperation.

² During 2012, KI rented out premises to external tenants for a total of SEK 42,280,000 (SEK 37,849,000). There is no separate cost accounting for this activity but full cost coverage is taken as the starting point, which is why the cost i specified in line with the revenue. KI’s policy is to rent out entire buildings if possible in order to have full right of disposition over its premises portfolio. Vacancies which may then arise are used as a premises provision for future needs through renting.

Note 3. Revenue from grants31/12/2012 31/12/2011

Revenue from grants from other authorities 983,626 818,684

Revenue from grants, non-Government 1,270,792 1,279,589

2,254,418 2,098,274

The reduction in interest revenue at the Swedish National Debt Office is due to a lower rate of interest on the interest account in 2012 compared with 2011. The annual average interest rate on the interest account for 2012 was 1.47 per cent (1.78 per cent). Capital gain on disposal of financial fixed assets was SEK 2.7 million (SEK 6.5 million) and accounts for the decrease in other financial revenue.

Note 4. Financial revenue31/12/2012 31/12/2011

Interest on Swedish National Debt Office interest account 46,971 55,329

Other financial revenue 7,931 10,333

54,902 65,662

31/12/2012 31/12/2011

Salary costs excluding employer fees, pension premiums and other fees in accordance with laws and agreements 1,833,872 1,752,782

Employer fees, pension premiums and other fees in accordance with laws and agreements 894,596 860,645

Doctoral grant 70,061 66,218

Other staff costs 72,696 73,705

2,871,225 2,753,350

Note 5. Staff costs

In 2012, staff costs increased by SEK 117.9 million, or 4.3 per cent, compared with the previous year. In October 2012, KI had 4,768 employees, an increase of 65 when compared with the same period in 2011. The item Employer fees, pension premiums and other fees for 2011 has been revised due to changes in accounting principles in 2012 regarding SPV pre-miums for doctors holding combined positions. These are reported as cost reductions instead of revenue. See Note 2.

At the end of the year, KI’s premises portfolio totalled 213,881 m² (200,859 m²). Premises costs rose in total by approximately SEK 81 million compared with 2011. The cost increase is primarily due to increased premises occupancy and on-going infrastructure investments. Also see the section on infrastructure.

Note 6. Premises costs

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74 Karolinska Institutet Annual Report 2012

Notes

Note 7. Other operating costs31/12/2012 31/12/2011

Remuneration for clinical education and research(medical training and research agreement funding) 574,400 566,553

Other operating costs 1,194,513 1,078,293

1,768,913 1,644,846

Note 9. Revenue collection operations

The balance relates to the net change in potential bad debt losses for non-payment of patient fees at the Department of Odontology.

31/12/2012 31/12/2011

Interest on Swedish National Debt Office loans 5,917 7,138

Other financial costs 3,093 21,528

9,010 28,665

Note 8. Financial costs

In 2012, financial costs fell by SEK 19.7 million compared with 2011. The reduction is due to a lower rate of interest on loans at the Swedish National Debt Office. The annual average interest rate on call loans was 1.47 per cent (1.78 per cent). This reduction in the item Other financial costs is largely due to lower costs relating to exchange losses on the sale of securities, SEK 1.2 million (SEK 15.6 million). The reversal of 2011’s write-down of securities results in a negative impact amounting to SEK -1.5 million.

Note 10. Change in capital by business area

Balanced change in capital (A)

Change in capital for the year (B) Total (A+B)

Activity

First- and second-cycle education

Education in accordance with public service agreement 125,339 -20,583 104,756

Commissioned work 13,798 9,205 23,003

Total 139,137 -11,378 127,759

Research/third-cycle education

Doctoral education and research 900,276 128,698 1,028,975

Contract research 54,034 22,207 76,241

Total 954,311 150,905 1,105,216

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Karolinska Institutet Annual Report 2012 75

Notes

Note 12. Improvement expenditure on property owned by others

Applied depreciation periods: 10 years 31/12/2012 31/12/2011

Opening acquisition value 102,278 102,570

Acquisitions for the year 0 -292

Transfer from installations in progress 0 0

Minus acquisition value of scrapped/sold equipment -17,253 0

Closing acquisition value 85,025 102,278

Opening accumulated depreciation -41,205 -31,132

Minus opening accumulated depreciation for scrapped/sold equipment 7,814 0

Depreciation for the year -9,004 -10,073

Closing accumulated depreciation -42,395 -41,205

Book value 42,631 61,073

Sold/retired assets

Capital gain 0 0

Capital loss 9,429 0

Note 11. Intangible fixed assets

Applied depreciation periods: 5 years 31/12/2012 31/12/2011

Opening acquisition value 38,500 34,355

Acquisitions for the year 389 4,145

Minus acquisition value of retired/sold rights -5,917 0

Closing acquisition value 32,972 38,500

Opening accumulated depreciation -29,957 -25,290

Minus accumulated depreciation for retired/sold rights 5,917 0

Depreciation for the year -2,132 -4,667

Closing accumulated depreciation -26,172 -29,957

Book value 6,800 8,543

Retirement refers partly to Effica (patient debiting system for dental care) and partly to database licenses for bibliometric analysis, SEK 5,917 thousand in total.

Note 13. Machinery, equipment, fixtures and fittings, etc.

Applied depreciation periods: 3 years, 5 years, 10 years 31/12/2012 31/12/2011

Opening acquisition value 2,010,676 1,909,570

Acquisitions for the year 224,460 157,831

Transfer from installations in progress 20,859 15,486

Minus acquisitions value of scrapped/sold equipment -57,276 -72,211

Closing acquisition value 2,198,720 2,010,676

Opening accumulated depreciation -1,405,087 -1,316,255

Minus accumulated depreciation for scrapped/sold equipment 48,143 71,534

Depreciation for the year -178,855 -160,366

Closing accumulated depreciation -1,535,799 - 1,405,087

Book value 662,921 605,589

Sold/retired assets

Capital gain 0 74

Capital loss 8,729 603

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76 Karolinska Institutet Annual Report 2012

Notes

Note 14. Fixed assets under construction31/12/2012 31/12/2011

Opening acquisition value 31,438 19,557

Acquisitions for the year 54,694 27,367

Transfer to assets account -20,859 -15,486

Accumulated acquisition value 65,272 31,438

Fixed assets under construction include improvements to KI’s campus areas. These projects run for several years, which is why the transfer to the assets account may be lower than the opening balance.

Karolinska Institutet Holding AB (100 %) 31/12/2012 31/12/2011

Nominal value 3,000 at SEK 100 each 300 300

Book value 55,458 102,443

Note 15. Shares and participations in wholly-owned and part-owned companies

Shares in KI Holding are valued at SEK 47 million lower than at the previous closing of the accounts. This is due to the KI Holding group’s equity capital having diminished by SEK 47 million during the year, of which SEK 34 million resulted from holdings in Karolinska Development being valued at a lower amount. At the year’s start, Karolinska Development was valued at the market price of SEK 24,00 per share, and at year’s end the market price was 15,30 per share.

According to the preliminary as yet unrevised revenue statement and balance sheet for 2012, Karolinska Institutet Holding AB shows a result of SEK -32.4 million (SEK -6.9 mil-lion). Net sales for the year preliminarily total SEK 42.8 million (SEK 47.4 million). The preliminary net sales for the year was, in total, SEK 73.5 million (SEK 122.9 million), with preliminary equity of SEK 55.5 million (SEK 103.3 million). The comparison figures in brackets relate to 2011’s confirmed balance sheet figures. For a more detailed description of Karolinska Institutet Holding AB, see the section entitled Collaboration.

Note 16. Other long-dated securities holdings (relates to asset management)

Shares and participations 31/12/2012 31/12/2011

Book value 143,607 141,525

Market value 152,534 141,525

Bonds, etc.

Book value 92,645 103,434

Market value 99,331 108,194

The investment fund portfolio had developed positively during 2012, and the market value exceeded the book value. 2011’s write-down of the book value of securities holdings (SEK 1.5 million) has consequently been appreciated in 2012.

31/12/2012 31/12/2011

Other receivables 303 772

Note 18. Other receivables

31/12/2012 31/12/2011

VAT receivables 81,325 69,374

Other government receivables 13,689 10,700

95,014 80,074

Note 17. Receivables from other authorities

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Karolinska Institutet Annual Report 2012 77

Notes

Note 19. Prepaid costs31/12/2012 31/12/2011

Prepaid premises costs 130,867 120,419

Other prepaid costs 20,611 8,181

151,478 128,600

31/12/2012 31/12/2011

Accrued revenue from grants, other government authority 25,584 32,913

Accrued revenue from grants, non-government 182,149 171,648

207,733 204,561

Note 20. Accrued revenue from grants

Here, accrued costs are reported for grant-financed activities where remuneration is received afterwards and where agreements/contracts exist to confirm this.

Note 21. Other accrued revenue31/12/2012 31/12/2011

Accrued contract revenue 8,230 9,340

Other accrued revenue 2,282 5,446

10,512 14,787Under the item Accrued contract revenue, accrued costs are reported for contract-financed activities where remuneration is received afterwards and where agreements/contracts exist to confirm this.

Note 22. Settlement with the Government31/12/2012 31/12/2011

Revenue collection

Opening balance -16,690 -14,820

Reported against revenue headings (-) -2,114 -1,871

Funds from interest account credited to revenue headings (+) 1 0 **)

Liabilities relating to Revenue collection -18,803 -16,690

Funding in interest-bearing flows

Opening balance *) -90,132 -71,796

Reported against funding (+) 2,585,348 2,456,146

Funding credited to the interest account (-) -2,573,813 -2,455,505

Repayment of funding 28,812 -18,961

Liabilities related to funding in interest-bearing flows -49,785 -90,116

Other receivables/liabilities on the government’s central account at the Riksbank

Opening balance 16,372 14,495

Deposits in non-interest-bearing flows (+) 2,162 1,882

Payments in non-interest-bearing flows (-) -76 -5

Claims on the government’s central account at the Riksbank 18,458 16,372

Balance -50,130 -90,435

With regard to first-level education funding, KI has exceeded the funding cap by SEK 11,208 thousand, including December performances from 2011. In addition, KI has settled SEK 327 thousand relating to an opening funding saving from the special funds for education of healthcare professionals (2:55 funding item 11). In relation to funding for first-level education (the funding cap), 2012 saw KI repay that part of the closing funding amount for 2011 that exceeded 10 per cent of the year’s revenue (SEK 28,812 thousand).

*) During the year, a previous discrepancy (SEK 16 thousand) against the Government report in Hermes was adjusted. This table shows the adjustment of the opening transfer amount. Hence the difference between the closing funding savings in 2011 and the opening funding savings of 2012. See also the funding report.

**) Correction of the 2011 amount. Should be 0.

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78 Karolinska Institutet Annual Report 2012

Notes

31/12/2012 31/12/2011

Opening provision 11,548 14,694

Change in pension provisions for the year -2,530 -1,229

Pension payments for the year -1,579 -1,916

Closing provision 7,438 11,548

Note 25. Provisions for pensions and similar obligations

Note 27. Swedish National Debt Office loans31/12/2012 31/12/2011

Opening balance 400,245 376,343

New loans 175,100 131,285

Repayments for the year -133,009 -107,383

Liabilities to the Swedish National Debt Office 442,336 400,245

Granted loan framework at the Swedish National Debt Office 520,000 440,000

31/12/2012 31/12/2011

Disposal of radiation source 2,000 2,000

Skills exchange and skills development initiatives 37,776 36,013

Closing provision 39,776 38,013

Note 26. Other provisions

Note 24. Administrative capital

Government capital

Profit partici-pation in

subsidiaries

Balanced change

in capital

Change in capital according to the

Swedish Financial Accounting

Standards Council

Total administrative

capital

Opening balance 5,238 96,969 949,303 144,506 1,196,016

Previous year’s allocation 475 144,031 -144,506 0

Corrected opening balance 5,238 97,444 1,093,334 0 1,196,016

Change in equity, subsidiary -15,444 -15,444

From the National Public Art Council

Change in capital for the year 107,989 107,989

Closing balance sheet total 5,238 82,000 1,093,334 107,989 1,288,561

Change during the year 0 -14,969 144,031 -36,517 92,545

Change in capital by business area is detailed in Note 10.

Note 23. Balance of Swedish National Debt Office interest account

31/12/2012 31/12/2011

Balance of Swedish National Debt Office interest account 3,244,073 3,191,142

of which short-term liquidity needs 0 0

Granted, unused credit on Swedish National Debt Office interest accounts stands at SEK 153.8 million.

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Karolinska Institutet Annual Report 2012 79

Notes

Note 30. Other prepaid revenue31/12/2012 31/12/2011

Prepaid contract revenue, other government authority 54,372 55,035

Prepaid contract revenue, non-government 239,661 302,956

Other prepaid revenue, other government authority 547 5,290

Other prepaid revenue, non-government 8,163 7,591

302,743 370,871

Prepaid contract revenue relates to non-accrued costs for contract-financed activities where remuneration is paid in advance.

Note 28. Accrued costs31/12/2012 31/12/2011

Accrued salaries 21,171 28,828

Holiday pay liabilities 83,343 84,161

Accrued cost to the National Government Employee Pensions Board for pension funds 3,032 10,522

Other accrued costs 25,484 16,012

133,031 139,522

Note 29. Unexpended grants31/12/2012 31/12/2011

Unexpended grants, other government authority 786,534 773,373

Unexpended grants, non-government 1,313,438 1,279,324

Unexpended grants asset management 213,030 223,925

2,313,002 2,276,622

These liabilities relate to non-accrued costs for grant-financed activities where remuneration is paid in advance.

Note 31. Contingent liabilities

31/12/2012 31/12/2011

Contingent liabilities 183,900 0

Contingent liabilities relate to commitments regarding the construction of the upcoming Biomedicum building.

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80 Karolinska Institutet Annual Report 2012

The university board

Remuneration paid to the Board of Karolinska Institutet in 2012 and details of other commissions (The commissions listed are board memberships and council memberships for other government authorities, as well as directorships of Swedish and foreign limited companies.)

The University Board

SusanneEberstein VästernorrlandPoliceBoard,chair 66,000Chair TheNationalSwedishPoliceBoard,member SwedishCommissionforSecurityandIntegration,member JudicialAppointmentsBoard,member HarrietWallberg-Henriksson KarolinskaInstitutetHoldingAB,member 1,565,666Presidentuntil31/12/2012 TheBoardofStockholmScienceCityFoundation,member StockholmSchoolofEntrepreneurshipSSES,member BiomedicalSciencesInternationalAdvisoryCouncil,Singapore,adviser TheTransparencyCouncilofStockholmCountyAdministrativeBoard,member TheDanishCouncilforResearchPolicyAndersHamsten PartnerandchairmanoftheboardinMedScientia 912,033Presidentfrom01/01/2013 ScientificAdvisoryBoard CarnegieHealthcareFunds,member Heart-LungFoundation’sResearchCouncil,member ProfessorNannaSvartzFoundation,member KingGustafV80yrFoundation,deputyboardmember Lisa&JohanGrönbergFoundation,director SalusAnsvarFoundation,director

AnnikaAndersson, PantorEngineeringAB,chair 28,000ViceChair DanAndersson TheSwedishCancerSociety’sfinanceboard 28,000

EliasArnér BiochimicaetBiophysicaActa–GeneralSubjects,Elsevier,editor 770,184 IMCOCorporationLtdAB,director PRIMABarn-ochVuxenpsykiatriAB,director

AndersBlanck WelfareDevelopmentCouncil,member 28,000 TheAnti-CorruptionInstitute,member SwecareAB,member SwecareFoundation,member EvaFernvall e-HealthInstitute,LinnaeusUniversityofKalmar,chair 28,000 IQ,subsidiaryoftheSwedishAlcoholRetailMonopoly,member EskilFranck Governmentappointedspecialinvestigatorformoreeffective 28,000 methodsagainstviolentextremism

Other commissions Salary/Fee SEK

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Karolinska Institutet Annual Report 2012 81

The university board

Hans-GustafLjunggren MemberScientificAdvisoryBoard,UmeåCenterforMicrobialResearch 734,280 (UMCR) MemberInternationalAdvisoryBoard,HannoverBiomedicalResearchSchool MemberBoard,ScandinavianFoundationforImmunology President,theSocietyforNaturalImmunity HeadofResearch,CellProtectNordic PharmaceuticalAB(StartupBiotech) TorbjörnRosdahl Noexternalcommissions 28,000 MarieWahren-Herlenius ToreNilssonFoundation,director 723,648 RocognitionAB,director JanAndersson, CentreforTranslationalMolecularMedicine,theNetherlands, 1,145,769VicePresident,Adjunct scientificadviseruntil31/12/2012 TheFlemingsbergScienceFoundation,member TheCarnegieFoundation,scientificadviser TheCenterforMolecularMedicine,director JournalofInternalMedicine,editor

KerstinTham TheVårdalFoundation’sideatesting–Challengesofageing,coordinator 1,031,941VicePresident,Adjunct BoardofEuropeanMasterofScienceinOccupationalTherapy,memberfrom01/01/2013 STROKEassociation’sresearchcouncil,member

TobiasBrosjö Noexternalcommissions 28,582until31/12/2012

FeliciaFixell Noexternalcommissions 43,999until31/12/2012

ÅsaSamuelsson Noexternalcommissions 337,017until31/12/2012

ErikHellsing CaféPartnerScandinaviaAB,deputyboardmember 224from01/01/2013

ArashHellysaz HopeGroupAB,deputyboardmember 196,040from01/01/2013

HampusEksell Noexternalcommissionsfrom01/01/2013

Other commissions Salary/Fee SEK

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82 Karolinska Institutet Annual Report 2012

The University BoardBack row: Anders Blanck (government appointee); Torbjörn Rosdahl (government appointee); Christina Hammarstedt (staff representative*); Patriq Fagerstedt, (staff representative*); Eskil Franck (government appointee); Dan Andersson, (government appointee); Gunnar Stenberg (staff representative*); Erik Hellsing (student representative); Hampus Eksell (student representative); Bengt Norrving (University Director, primary rapporteur)

Front row: Elias Arnér (faculty representative); Kerstin Tham (Vice-President, additional member); Annika Andersson (government appointee); Anders Hamsten (President, ex-officio member); Susanne Eberstein (Chair-person, government appointee); Eva Fernvall (government appointee); Hans-Gustaf Ljunggren (faculty representative); Arash Hellysaz (student representative);

Absent: Marie Wahren-Herlenius (faculty representative)

* Staff representatives have no voting right

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Karolinska Institutet Annual Report 2012 83

Decision on the annual report and assessment of internal control

The University Board hereby submits its annual report for 2012. We confirm that the annual report provides a true and fair impression of the authority’s results, costs, revenue and financial position. We also judge the authority’s internal management and control to be satisfactory.

Stockholm, 18 February 2013

SusanneEberstein,Chair EvaFernvallAndersHamsten,President EskilFranckAnnikaAndersson ErikHellsingDanAndersson ArashHellysazEliasArnér Hans-GustafLjunggrenAndersBlanck TorbjörnRosdahlHampusEksell MarieWahren-Herlenius

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84 Karolinska Institutet Annual Report 2012

Appendix

Aswithpreviousyears,KIreportsthefollowingperformancemeasures:• costperfull-timestudent(excludingcontracteducationand commissionededucation)• costperannualperformanceequivalent(excludingcontract educationandcommissionededucation)• costperpeer-reviewedscientificpublication• costofadoctoralstudentwithaneducationgrantor employmentatKI

Definitions Full-timeequivalentsandannualperformanceequivalentsaretheperformancescarriedoutduringtheyearandaredefinedinaccordancewiththepublicserviceagreement.CostsrelatetocostsreportedfortheyearwithintheoperationalareaofGovernmentFunding-financedfirst-/Bachelor’sandsecond-cycle/Master’seducation.Costsalsoincludegrant-financedandfee-financedcostsassociatedwiththeactivity.However,contracteducationandcommissionededucationarenotinclu-ded.

Itshouldbenotedthatfull-timestudentsandannualperformanceequivalentshavebeenrelatedtocostsindividually.Itisnotthereforepossibletorelatecostsperfull-timestudentandannualperformanceequivalenttothepricetagsusedinthegovernment’sallocationofresourcestotheeducationalinstitutions.Inthiscontext,itshouldbenotedthatthecostsarealsoincludedintheclinicalsectionsofphysicianandspeechtherapisteducation(correspondingtothefundingformedicaltrainingandresearch)anddentistryeducation(thedentalcarecentre).

Themeasurementsofcostsperfull-timestudentandannualperformanceequivalentaredeemedtoberelativelysecure,astheconstituentelementsrelatetothecurrentyearandareconventional.

Costperpeer-reviewedscientificpublicationincludesallcostsrelatedtoresearchandeducationatthird-cyclelevel,includingcontractresearch.Thereisnoseparationoftheactualcoursecomponentsindoctoraleducationbecausetheycannotbereadfromtheaccountingsystem.

Intheconceptofscientificpublication,KIhaschosentotakearticlesandoverviewarticlesfromitsbibliometricdatabasebasedondatafromThomsonReuters’citationdatabases(WebofScience).

KIhasalsochosentoreport,underKeyratios,thenumberofpublicationsunfractionated(withouttakingintoaccounttheproportionofapublicationattributabletoauthorsattheeducationalinstitutioninquestion).KIhasnotreportedanyinformationregardingpublicationsforthelastyear(2011)asthereisadelayinreceivingreports.

Themeasurement“costperpeer-reviewedscientificpublica-tion”shouldbeviewedwithcautionsincethereisnodirectlinkbetweentheyear’scostsandthesameyear’spublishedarticles.

Theresearchworkinvolvedinanarticlemayhavetakenmanyyears.Inviewoftheabove,thismeasurementshouldberegardedasanapproximatevalue.

Finally,itshouldbeemphasisedthattheseperformancemeasurementsdonotsayanythingaboutthequalityofoperations.Thedevelopmentofthethreemeasurementsiscommentedonbelow. 2012 2011 2010 2009 2008

Cost per FTE student,

SEK thousands 154 146 144 143 143

Cost per annual performance

equivalent, SEK thousands 170 159 157 159 151

Cost per peer-reviewed scientific

publication, SEK thousands 1,043 1,062 1,022 925

(Excerpt from Key ratios)

Costs per full-time student and annual performance equivalentThecostperfull-timestudentandannualperformanceequivalenthasincreasedby8and13percentrespectivelyduringtheperiod.Theincreasebetween2011and2012isrelativelyhigherthanthepreviousyear’sfigure,butsomecautionshouldbeexercisedwhenmakingcomparisonsbetweentwoyears.Inthecaseof2012,forexample,thenumberofcourseweekswas39whilethelevelofperformancesimultaneouslydiminished.AlsorefertothesectiononBachelor’s(first-cycle)andMaster’s(second-cycle)education.

Cost per peer-reviewed scientific publicationThenumberofpublicationshasincreasedduringtheperiod,whilethecostshavealsosomewhatincreased,resultinginahigherunitcost.However,KI’sinternalmanagementmodelinresourceallocationbetweendepartmentsputsapremiumonqualityintheformofcitationsandthejournals’reputationandimpact,ratherthanthenumberofarticles.Between2010and2011,theunitcostdecreasedasaresultoftherelativeincreaseinpublishing.KIisnotreportingtheoutcomeforthepastyearbecausethereisadelayintheregistrationofthenumberofpublications.Itshouldbenotedthatthecostperpublicationonlyprovidesanindicationofproductivityandnotthescientificimpact.Alsoseethesectiononresearchanddoctoral(third-cycle)education.

Performance and costs within education at third-cycle level and cooperationAsinpreviousyears,KIhasreportedthecostforadoctoralstudentwithemploymentoragrantunderthesectiondoctoraleducation.

For2012,thecostforeducationprovisionwasanaverageofSEK327,000fordoctoralstudentswithemploymentoraneducationgrantatKI(weightedaverage).Thesecostscanbe

Costs for performance

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Karolinska Institutet Annual Report 2012 85

Appendix

obtaineddirectlyfromthefinancialandstaffreportingsystem(572doctoralstudentswithemploymentand380witheducationgrantsinOctober2012.)Inaddition,therearethefollowingcosts:• supervision• operatingcosts• premises• equipment(depreciationcosts)• indirectcosts.

Supervisoryworkhasbeenestimatedatapproximately20percentofanannualFTEworkloadbasedonasurveyconductedatKIin2011.Therefore,theaveragesalarycostforasupervisorisestimatedatSEK153,000.

OperatingandpremisescostsalongwithdepreciationareproportionedbasedonthenumberofannualFTEemployees,includingdoctoralstudentswitheducationgrantswithintheoperationalarearesearchanddoctoraleducation.Thesamecalculationisusedfordoctoralstudentsasforsupervisors.

ThetotalcostforadoctoralstudentincludingsupervisorcostscanthusbeestimatedatSEK1190(thousand)afteroverheadchargeshavebeenaddedforindirectcosts(SEK1,161(thousand)in2011).

Thedataisbasedinpartonassumptions,whichiswhythecostshouldbeviewedasapproximate.Atableofcostsandcommentscanbefoundunderthesectiondoctoraleducation.

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Karolinska Institutet Annual Report 2012

This publication is an abridged version of the document

delivered to the Swedish Government in February, 2013

Compiled by

University Administrative Department

Karolinska Institutet

171 77 Stockholm

ki.se

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Photo

Gunnar Ask, Olle Nordell, Ulf Sirborn, Erik G Svensson, Thinkstock

Graphic design

Carina Persson,

Communications and Public Relations Office, Karolinska Institutet

Print

Davidsons Tryckeri

ISBN 978-91-85681-53-2

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