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http://genex-umb.sourceforge.net
GenExplorerTeam Members
Prasoon Kejriwal
Sumana Adma
Ziping Zhu
Chitra Karki
Project Advisor Client
Prof. Ethan Bolker Prof. Brian White
http://genex-umb.sourceforge.net
About GenExplorerAbout GenExplorer Idea behind the project
Develop an education tool for beginning biology students
Simulation of “Central Dogma” of Molecular Biology
Why GenExplorer? Why do we think it’s a good project ?
Huge market for such an application in the education industry
Very long lifespan of the software product
Capable Team Members
About our client
http://genex-umb.sourceforge.net
Central DogmaCentral Dogma DNA Sequence
5'-AAGGCTATAACCGAGATTGATGCCTTCTTAAGAAGGTGTGAGGGGGC- 3'
3'-TTCCGATATTGGCTCTAACTACGGAAGAATTCTTCCACACTCCCCCGG- 5'
Pre-mRNA Sequence (Transcription)
5'-CCGAGAUUGAUGCCUUGAGUAGGACCUUAAGAAGGUGUGA- 3‘
mRNA Sequence (Splicing)
5'-CCGAGAUUGAUGCCUUUUUAAGAAGGUGUGAAAAAAAAAAAAAA-3'
Protein (Translation)
N-MetProLeuSerArgGlyPro-C
http://genex-umb.sourceforge.net
Are we re-inventing the wheel?Are we re-inventing the wheel?
Issues with current applications on the webDoes not allow user interactionAre not user friendly
Where do we come in?Understand the end user as closely as possibleHave a clear knowledge about the requirementMake an extremely user-friendly and flexible application
http://genex-umb.sourceforge.net
Market ProspectsMarket ProspectsBusiness Objective
Developing and providing courseware for both classroom and web-based education.
Target MarketK9-12, college students, or any other learners and educators in biology related
fields. Market Size and Opportunity
Schools where bioscience is taught Students Fast Growing Potential of Stock Market In Instructional Technology
Competitors There are about 351 companies doing educational software business.
Higher EdApollo Group (Phoenix University?)Career EducationConcorde Career CollegesCorinthian collegesDeVryEducation ManagementITT Educ. ServicesStrayer EducationUniversity of Phoenix online
http://genex-umb.sourceforge.net
Increasing Biodiversity Education MarketIncreasing Biodiversity Education Market
High school, Grade 9-12
16,380,951
College, undergraduate
14,375,764
Percent of public high school graduates taking selected Biology course is 91.2%
Earned degrees in various fields of biology conferred by degree-granting institutions in 2000-01: 42,252
(2000. US Census)http://nces.ed.gov/pubs2003/digest02/tables/dt141.asp
Growth of youth in last 10 years
http://genex-umb.sourceforge.net
Fast Growing Fast Growing Potential of Stock Market In Potential of Stock Market In Instructional TechnologyInstructional Technology
86.5%
13.5%
63.2%
36.3%
InstructionalHardware
InstructionalSoftware
Centralized Decentralized
-90%
-60%
-30%
0%
30%
60%
K9-12 -40.0 6.5% 20.8%
Higher Ed 22.4% 25.7% 45.4%
CorporateLearning
-61.0%
18.6% 48.9%
KnowledgeInfrastructure
-55.0%
10.6% 30.1%
KnowledgeSolutions
-5.9% 5.4% 14.7%
Sept. 2002
May 2003
J uly 2003
2.12.5
2.8
3.64.3
4.85.4
6.7
8.36
5.6
7.85
4.7
6.95
4.2
6.45
3.53
5.74
3.55
5.80*
0
2
4
6
8
10
91
-92
92
-93
93
-94
94
-95
95
-96
96
-97
97
-98
98
-99
99
-00
00
-01
01
-02
02
-03
03
-04
*
E-rate
District Spending
* Projected
Source: ThinkEquity Partners Knowledge Notes Newsletter Median YTD Price: Aug. 18, 2003 and July 7, 2003 compared to May 19, 2003 and Sept. 16, 2002
Source: QED Ninth Annual Technology Purchasing Forecast, 2003-2004 Preliminary Data
Instructional Technology
Expenditures in U.S. School Districts13-Year Trend Expenditures
(Billions)
http://genex-umb.sourceforge.net
TeamTeamIndividual Strong Points of Team Members
Prasoon Kejriwal Strong background knowledge Industrial experience in biotechnology
Ziping ZhuReal world experience in educational researchVery good knowledge of User Interface Design
Sumana AdmaGood knowledge of design principlesVery good knowledge of User Interface Design
Chitra KarkiVery good knowledge of User Interface DesignTaken the introductory Biol 111 and Biol 112 courses with the client
http://genex-umb.sourceforge.net
Project ManagementProject ManagementManagement Strategy
Have a detailed plan in the beginning and make sure each team member abides with itStrictly follow schedules and meet milestones.Maintain to-do listsCommunicate with the client on a regular basisFreeze requirements at an earlier stage in order to minimize risk of schedule slippage and late delivery.Compromise on scope in order to deliver a good quality product.
http://genex-umb.sourceforge.net
Project ManagementProject ManagementDesign Strategy
Spend lot of time on the system architecture design User centered design Simplicity and continuous refactoring
Development Strategy Pair programming Small releases Continuous integration
Testing Strategy Write tests ahead of coding Run tests before every small release
Risk Strategy Identifying Analyzing Planning Monitoring
http://genex-umb.sourceforge.net
MILESTONES
Scheduled Date Milestones Description
Oct 14, 03 Vision Statement Final Vision Statement signed by the customer
Oct 30, 03 Project presentationPresentation of the
project to the prospective venture capitalists
Dec 4, 03Submit requirements
document
Hard copy of Requirements document to be submitted to Prof.
Bolker
Dec 20, 03"Hello world" application
running
Testing and coding of a small program to
understand the tool better
Jan 21, 04 Iteration 1 First bug free version
Feb 1, 04First formal application
checkpointDemo of the application to Prof. Bolker and the client
Mar 11, 04Formal Alpha release demo
with documentation
Demo of the Alpha release of application to Prof. Bolker and the client
Apr 20, 04Formal Beta release demo
with documentation
Demo of the Beta release of application to Prof. Bolker and the client
May 01, 04 Production release (1.0).Presentation to public (poster, demo) shortly
thereafter.
May 11, 04 Maintenance release (1.1) Maintenance release (1.1)
http://genex-umb.sourceforge.net
GenExplorer so far…GenExplorer so far…
Project Website establishedWebpage weekly updated
First version of use cases approved by clientA major milestone achieved so far
First draft of User Interfaces madeTo be discussed with the client in next meeting
Preliminary schedule established
http://genex-umb.sourceforge.net
Features of GenExplorerFeatures of GenExplorer
User FriendlyThis application is being developed keeping in view that it would be used by beginning biology students who could be naïve computer usersInvolve users in design of interfaces
Easily available
Web based – can use the application directly on web without downloading
http://genex-umb.sourceforge.net
Features of GenExplorer Features of GenExplorer cont..cont..
Main Features Highlighting
Editing
Transcription / Splicing / Translation
Folding ( ?? )
Modes of GenExplorer Instructor / Student / TA
Interactive / Non – Interactive
Strict / Relaxed
http://genex-umb.sourceforge.net
HighlightingHighlightingDNA Sequence
5'-AAGGCTATAACCGAGATTGATGCCTTCTTAAGAAGGTGTGAGGGGGC- 3' 3'-TTCCGATATTGGCTCTAACTACGGAAGAATTCTTCCACACTCCCCCGG- 5'
Pre-mRNA Sequence (Transcription)5'-CCGAGAUUGAUGCCUUGAGUAGGACCUUAAGAAGGUGUGA- 3‘
mRNA Sequence (Splicing)5'-CCGAGAUUGAUGCCUUUUUAAGAAGGUGUGAAAAAAAAAAAAAA-3'
Protein (Translation)N-MetProLeuSerArgGlyPro-C
http://genex-umb.sourceforge.net
ConclusionConclusion
• Why invest money in GenExplorer?– Very interesting and useful project– Capable team members– Doable in the time constraint– Would be definitely used by over 350 beginning
biology students at UMass, Boston every year.
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