ABS Pueraria Mirifica Extract PF

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Anti Aging + Conditioning

ABS Pueraria Mirifica Extract PF

Technical Information:

• Code: 10642

• INCI Name: Water & Butylene Glycol & Pueraria Mirifica Root Extract

• INCI Status: Conforms

• Suggested Use Level: 1.0-10.0%

• Suggested Applications: Anti-Aging, Conditioning

Estrogens

• Primary female sex hormones

• Functions in the body:• Development of sex characteristics, such as breast tissue• Maintenance of healthy skin and bones

• Production decreases overtime during a gradual shift in hormone levels, known as menopause

• Decreased estrogen effects:• Hair growth• Wrinkle formation• Epidermal elasticity

Hormone Replacement Therapy

• Hormone Replacement Therapy (HRT) has become a common treatment used to combat symptoms of menopause and to prevent bone loss in postmenopausal women

• Contraindications of HRT which include the risk of developing breast cancer, deep vein thrombosis, pulmonary emboli and stroke have discouraged the use of certain HRTs

• These risks drove the desire to find a natural alternative to HRT

Phytoestrogens

• Phytoestrogens are chemicals produced by plants with mild estrogenic effects

• Flavonoids are the primary class of phytoestrogens

• Flavonoid sub-classes include:• Coumestans• Prenylated flavonoids• Isoflavones

• It is generally understood that phytoestrogens have structural similarities to estrogen which explains why these plant compounds would have similar effects in vivo

Pueraria Mirifica

• Commonly known as Kwao Krua

• Naturally rich in phytoestrogens

• Known for its antioxidant properties

Benefits: Reduces appearance of wrinkles Improves elasticity Increases collagen production

ABS Pueraria Mirifica Extract PFEfficacy Assay Results

Moisturization Study

-21%

2%

-7% -5%

20%

-7%

39%

26%25%

27%

17%

37%

35%

32%

6%

-30%

-20%

-10%

0%

10%

20%

30%

40%

50%

t=0 24 hours 1 week 2 weeks 3 weeks

Pe

rce

nt

(%)

Incr

eas

e

Base Lotion-Untreated Control

5.0% ABS Pueraria Mirifica PF-Untreated Control

5.0% ABS Pueraria Mirifica PF-Base Lotion

Results:ABS Pueraria Mirifica Extract PF is capable of increasing moisturizationwhen compared to both the untreated control as well as the base lotion

ProtocolEquipment: DermaLab Combo

Principle of measurement: Conductance, single frequency.

Subjects: 10 (m/f)

Test area: Volar forearms

Test quantity: 5mg

Frequency of application: Twice daily

ABS Pueraria Mirifica Extract PF

Technical Information:

• Code: 10642

• INCI Name: Water & Butylene Glycol & Pueraria Mirifica Root Extract

• INCI Status: Conforms

• Suggested Use Level: 1.0-10.0%

• Suggested Applications: Anti-Aging, Conditioning