Vision Hema

Blood cell image analysis systems

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VISION HEMATOLOGY

West Medica

West Medica feels strongly that innovation is the key to a brighter future and improves the quality of life for everyone. Development of “Vision” solutions for digital microscopy is a top priority and the main focus of West Medica.

Technology is an increasingly influential factor in many fields as new methods are established every day and that’s the reason why West Medica always tries to be one-step ahead. New analytical procedures are regularly introduced onto the market and as a result customers are often looking for solutions to keep up-to-date on the latest scientific developments.

Our market experience and extensive knowledge through research and close cooperation with end-users and field specialists allow us to develop and deliver high quality products. Throughout the years West Medica has participated in numerous congresses and exhibitions, as well as organized many seminars, workshops and master classes. We strongly feel that through Vision solutions we share our knowledge and experience with the world.

Continuous analysis and evaluation of our customers’ demands as well as close observation of market trends secures routine expansion of our product portfolio. We develop systems for specific applications that can be grouped in 6 categories. Namely: hematology, microscopy, cytogenetics, quality control, clinical laboratory and general medicine. Each system is a result of company’s field experience and extensive research as well as analysis of customers’ needs. To cater for individual necessities of each client, our systems are flexible enough to satisfy those requirements.

Our product portfolio, at this moment, includes complete systems for:

1. blood cell image analysis (Vision Hema)2. analysis, reports and management of digital albums in microscopy

(Vision Album, Vision Report, Vision Bio)3. analysis, reports and management of digital albums in fluorescence

microscopy (Vision Epi)4. chromosome analysis (Vision KaryoFISH)5. internal laboratory quality control (Vision QC)6. urine analysis (Vision Uri+)7. sperm analysis (Vision Sperm+)8. dermatoscopy (Vision Derma)9. ophthalmoscopy (Vision Omega)10. digital cameras, software and instruments

Coming developments include: automated chromosome analysis, analysis of human body fluids, bone marrow and urine sediment, solution for bacterial colonies analysis, as well as specialized products for cytology, histology, gynecology and other fields.

Digital microscopy

Digital microscopy is a digital environment for managing and analyzing microscopy data, which is obtained using a microscope, a camera, software and a computer.

Digital microscopy allows you to attain qualitative and quantitative results, which are either impossible to receive by other means or cost and time consuming.

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Improve your daily work

Close attention to an absolute completion of our product means that each step in a Vision system is closely supervised. Hardware production and delivery, software development and testing, installation of the system, user training, consultation and after-sales service and maintenance are most significant to us. Help and support of each client is always a priority. Success of our customers is seen as our own and that is why we do our best to exceed their expectations by ensuring market competitiveness and long-term performance of each system.

HardwareDevelopment and manufacturing of hardware (microscopes, digital cameras and other instruments to complement/simplify the analysis procedure) consume significant amounts of resources in both energy and materials. There are ongoing efforts to improve the effectiveness of operation as well as time and cost of the running. All elements of the system are mutually compatible to use in conjunction with one another.

SoftwareSoftware is necessary for an error-free operation of the system. Storage of digital samples presents users with an option of extensive documentation and a possibility of network capabilities. Improved algorithms guarantee quality control and unbiased analysis results. An overall platform for all software makes it easy to upgrade very quickly. Every system can be reconfigured at a later point in time to support a different set of tasks.

Installation and user trainingWe don't believe in «one-size-fits-all» and for that reason trainings and workshops are frequently organized in one of our offices or at your site. Our professional in-house training experts design tailored programs reflective of your individual practice and the unique end-user tasks. Requests and wishes of our partners form the basis of cooperation.

After-sales supportOur wide distribution network allows us to provide our customers with constant product availability and an efficient after-sales service with qualified personnel. Our specialists are glad to share their extensive experience and expertise. Mutually beneficial understanding and investment in relations with any professional are always important for us, with no differences for big or small business. Our sales network continuously broadens, as we always search for new distributors.

Vision systems are designed to maximize the use of advanced technology features and capabilities, optimise and standardize workflow and staff productivity as well as foster professional growth. Specialists that are looking for professional development and recognize new digital technologies are presented with unlimited resources in their field.

Your friendship and trust are very significant to us and our goal is to provide you with high quality and professional support.

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Vision Hem! systems

Efficient and professional solution for the hematology laboratory!

Our flagship Vision Hema is a blood cell identification and pre-classification system. Its aim is to automate and simplify a complex procedure of blood smear analysis. You work with a unified system where priority is given to efficiency and workflow optimization and standardization.

Vision Hema 1 — digital system for blood cell image analysis with loading of 1 slide. Cost-effective solution for small-sized laboratories

Vision Hema 8 — digital system for blood cell image analysis with simultaneous loading of up to 8 slides. Optimal solution for small- and medium-sized laboratories

Vision Hema 200 — digital system for blood cell image analysis with autoloader for loading of up to 200 slides. Effective solution for large-sized laboratories

Vision Hema Assist — digital system for blood cell image study. Budget solution for laboratories

Applications

clinical laboratory

hematology

oncology

blood transfusion stations

pharmaceutics

veterinary

research

education

remote consultations

specialist training

telemedicine

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Main benefits

1 Workflow automation and standardization

2 Automatic generation of blood cell gallery

3 Identification and pre-classification of leucocytes, erythrocytes and platelets

4 Morphological analysis of WBC and RBC

5 Quick validation of analysis results

6 Significant reduction in the qualified personnel's workload

7 Quality control and no “human error” factor

8 Report generation according to individual requirements

9 Full compliance with the rules and protocols of blood cell image analysis

10 Telemedicine and remote consultations with colleagues, education and medical councils

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Vision Hema 1

Vision Hema 8

— loading of 1 slide— bar code reader (option)

— simultaneous loading of up to 8 slides— Walk Away mode— bar code reader (option)— automated oil dispenser (option)

Cost-effective solution for small-sized laboratories

Optimal solution for small- and medium-sized laboratories

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Vision Hema 200

Vision Hema Assist

— standardization and automation of blood smear study— a significant reduction in study complexity and personnel’s workload

— !utoloader for loading of up to 200 slides— Walk Away mode— Random Access— STAT testing— continuous loading mode— bar code reader— automated oil dispenser

Budget solution for laboratories

Effective solution for large-sized laboratories

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Workflow automation and standardization

Preparation of microscopic blood smear slides

One of the most important analysis stages in a laboratory is the pre-analytical phase as it affects the speed and quality of the analysis process. Use standardized tools to prepare and stain a blood smear.

Scanning and cell identification

Vision Hema automatically scans a microscopic sample, collects data for analysis, sorts blood cells and saves results in the database.

It’s much easier to view an automatically generated gallery of blood cells on the computer screen rather than to spend hours looking into microscope eyepieces. Vision Hema offers a wider cell differential count and the possibility to view cells provides an additional visual control if there LV�D�QHHG�WR�FRQ¿UP�the analysis

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Only 5 easy steps

Validation of WBC, RBC and platelets

The specialist is free from routine monotonous work. Analysis results are displayed in galleries of cells and arranged in groups. All you need to do is review and verify the results.

Report generation

Report is generated based on analysis results, which you can send to your colleagues by email or simply print out.

Benefits of Internet connection

Connect several workplaces to a remote server and hold video conferences with colleagues from around the world, exchange analysis results, publish your research on specialized online networks.

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Easy and convenient operation

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Analysis status

Analysis status is used for convenient management of a laboratory workflow

new

in process

scanning

pause

scanned

error

completed

delayed

Comments

Leave your comments and marks right on the blood cell image

Warnings and flags

Visual signals when analysis results are out of the reference range

Show group

Enable/disable the display of blood cell group

It only takes a click to see patient records and analysis results

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Detection control

Color indication of cell type

Quality assessment of sample preparation and leucocytes distribution.

Main toolbar

Basic working tools. Management of patients records, analysis results and functions of blood cell image analysis. Connection to a hematology analyzer. Report generation.

Patients

All patient data is presented in chart form that can be adjusted individually by choosing the required fields: ID, name, surname, date of birth, age, etc. Folders, filters and sorting will help you search quickly.

Analyses

All analyses are presented in chart form and contain the following fields: ID, status, warning flag, analysis date and comments. Scheduled tests are formed into a worksheet.

Results

Results have several modes to review and correct the information: general analysis information, final page with analysis results, gallery to verify obtained results, detection control shows the scanning path and distribution of found leucocytes, morphological analysis of found objects.

Blood cell gallery

Gallery shows identified objects according to groups. Place your comments and marks right on the blood cell image.

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Neutrophiles

Lymphocytes

Monocytes

Eosinophiles

Basophiles

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Blood cell identification and pre-classification

WBC with differentiation in 15 groups*:

1. Band neutrophiles2. Segmented neutrophiles3. Eosinophiles4. Basophiles5. Monocytes6. Blasts7. Promyelocytes8. Prolymphocytes9. Myelocytes10. Metamyelocytes11. Lymphocytes12. Large granular lymphocytes13. Plasma cells14. Reactive lymphocytes15. Unknown

RBC with differentiation in 6 groups

1. Erythrocytes — Identification by size (normocytes, microcytes, macrocytes, megalocytes) — Identification by color (normochromic, polychromatophilic, hypochromic,

hyperchromic) — Identification by shape (microspherocytes, target cells, ovalocytes,

stomotocytes, sickle cells, schistocytes, acanthocytes, echinocytes, teardrop cells)

2. Proerythroblasts3. Basophilic erythroblasts4. Polychromatophilic erythroblasts5. Oxyphilic erythroblasts6. Erythrocytes with inclusions — Howell-Jolly bodies — Cabot rings — Basophilic granules

Platelets with differentiation in 3 groups

1. Normal2. Microgeneration3. Macrogeneration

more then 20 types

of blood cells

* Accuracy of identification for normal groups (S.NEU, B.NEU, LYM, MON, EOS, BASO) is 90-95%. Identification and validation for pathological and young groups is made by a qualified specialist. Following the requirements of pre-analytical stage is obligatory for accurate identification.

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Scanning profiles

Adaptive scanning system determines erythrocyte distribution level and slide edges

Platelet Erythrocyte

Scanning magnification (objective) 40x, 50x or 100x.

Quantity of cells for analysis.

Sample scanning path.

Profile settings include the choosing of:

Leucocytes

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Analysis results

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Result interpretation and comments

Brief conclusion for a report on the analysis results and recommendations for further examination.

Templates

Customize a set of frequently used text fields

Text templates for the report speed up the process by selecting a standard conclusion or recommendation.

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Final results

CBC data

Absolute concentration values of various cells and hemoglobin, as well as the traditional values of various indices calculated, determined by hematology analyzer.

WBC differential

Relative ration of different WBC classes.

Erythrocytes

Erythrocyte changes according to the data from morphological research.

Price-Jones curve

Erythrocytes distribution according to diameter, with indication of mean value.

Erythrocytes with inclusions

The frequency of erythrocyte detection depends on the type of the most common erythrocytes inclusions (Jolly bodies, Cabot rings, basophilic granules).

Erythrocyte parameters

Quantitative presentation of most important features of erythrocyte morphology (according to size, hemoglobin content and form).

Erythrocytes by size

Quantitative description of type and degree of anisocytosis severity.

Erythrocytes by color

Quantitative description of erythrocyte distribution by staining degree, characterization of anisochromia and appearance of polychromatophiles.

Erythrocytes by shape

Frequency of erythrocyte appearance with an abnormal cell form, characterizing quantitative type and degree of poikilocytosis.

Platelets

Distribution of various platelet generation according to their relative content.

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Results of blood cell image analysis performed by Vision Hema system and counting of cells by an expert match by 90-100%. The system considerably reduces the workload of highly skilled personnel

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Blood cell validation

Validation

Identification of blood cells is primarily made according to the algorithms included in Vision Hema system, forming image galleries. After the scanning process for blood smear is completed, laboratory personnel performs the validation of analysis results, makes corrections if necessary and confirms the analysis results.

Tree of analysis objects

You can add new groups of blood cells for manual classification, place non-identified cells in these groups and carry out morphological measurements. Each folder can include unlimited number of sub-folders.

Multi-gallery mode

Working with several galleries simultaneously. Quicksort between the galleries.

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Drag&Drop

Validation

Simply grab a cell with the mouse and drag it to the required cell group.

“Hot” keys

Validation is made in “one click”, and object moves from one folder to another.

Masks

Displays masks of nucleus and cytoplasm of the cell.

Quick preview

Magnification of a single cell allows to quickly assess morphology of the object.

Marks and comments

Color marks and comments.

Show on slide

Live microscopy of objects presented in the gallery.

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Morphological analysis

Classify analysed objects using required criteria to generate a report. Select a required number of groups and define a measurement range for each one of them:

— size of selected objects— location— optical parameters— quantity

The system will measure and display results visually in a histogram form and breakdown the gallery into appropriate groups.

You can save frequently used methods to make them easily accessible in the future.

Morphological analysis

Morphological cell analysis is one of the most important parts in hematological research. Vision Hema system provides this possibility

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Analysis example

Neutrophile research

1 Select cell group for analysis.

2Choose analysis method: classification and/or measurements.

3Classify objects into groups, selecting a range for each one.

4 Select measurement parameters that are of interest.

5 Generate and print out your analysis report.

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Vision Hema+

Expand the capacity of your laboratory by connecting a hematology analyzer with Vision Hema system. A modern approach to diagnosis that combines microscopy, digital image processing and analytical data from hematology analyzer.

Various features

Quality control

Assessment of diagnostic sensitivity, specificity and efficiency. Signals about problems and errors to correct blood smear preparation procedure or service the functional parts of the system.

Veterinary application*

Collection and identification of animal's blood cells. Scientific research and complete blood count.

Leucocyte distribution

Detection control to assess leucocyte distribution and quality of sample preparation. Color indication of cell type.

Scanning while working

While blood smear is being scanned, you can still work with other samples and analyses, prepared earlier.

Diagnoses

Adjustable reference guide of diagnoses allows to track the formulation, modification or clarification of the diagnosis.

* Information on request

Atlas

Atlas of microscopic objects has a customizable hierarchic structure. Add the required sections and text comments to microscopic images.

Refractory anemia with excess blasts

Acute leukemia

Iron-deficiency anemia

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Virtual sample preparation

Scanning of microscopic slides and generation of digital samples

A digital sample is indispensable when you have an object that can’t be seen entirely in the field of view with the required magnification — it is just not possible to see it completely without creating a “virtual sample”

I keep microscopic slides as digital samples RQ�P\�RI¿FH�FRPSXWHU��I organize them the way I want and I always ¿QG�ZKDW�,�DP�ORRNLQJ�for easily. Digital slides never fade or get damaged like the glass. I do not worry about breaking or losing it

Working with frames

The feature “show on slide” allows to find the requested field of view during repeated microscopy.

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Connecting several working places to a remote server allows an organization of a single information environment for the medical institution

Analyses are performed on one working place, for example, in laboratory, and a doctor can make validation on another one — for example, in his office

Data import/export to other information networks (LIS/HIS).

Laboratory 1

Laboratory 2

Laboratory 3

Remote access and network capabilities

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Medical councils

Discuss difficult cases simultaneously with several specialists

Formulate an accurate diagnosis, as well as tactics and strategy for further examination and treatment, together with your colleagues.

Education

Education today is easier and more effective using modern technologies

Demonstration and discussion of the practical and theoretical material on the screen makes the learning process clearer and easier.

Organize video conferences with colleagues from around the world.

Publish your research on specialized online networks.

Share information with people wherever they are. Send your reports by email.

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Report form

Report name

Laboratory logo

Analysis information

Patient information

Date and time of sample collection/delivery/report

Institution information

Comments about a patient/sample, etc.

CBC data

WBC differential

Leucocyte gallery

Erythrocytes

Price-Jones curve

Vision system offers report templates for every case — from simple analysis on 1/3 of the page to detailed conclusions on the research carried out. Use a standard report form or design it yourself according to your requirements.

Platelets

Erythrocytes by size

Erythrocytes by color

Erythrocytes by shape

Interpretation of results

Comments

Diagnoses

Previous diagnoses

Validation

Date and time of validation

Signature

Page number

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Report

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Report example 1

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Report example 2

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Comparative characteristics

Description

Motorized biological microscope with “infinitive” optics and Vision digital camera. Preview live video on monitor screen. Loading 1 slide.

Motorized biological microscope for 8 slides with “infinitive” optics and Vision digital camera. Preview live video on monitor screen. Simultaneous loading of up to 8 slides.

Motorized biological microscope with “infinitive” optics and Vision digital camera. Preview live video on monitor screen. Barcode reader for automated sample identification. Autoloader for loading of up to 200 slides.

Personal computer with Vision software and a high resolution monitor. Scanning the blood smear.

Identification and pre-classification of blood cells, including differentiation of leucocytes, erythrocytes and platelets.

Morphological analysis of blood cells. Classification of objects according to a required criteria.

Atlas of microscopic objects. Customizable diagnoses reference guide.

Audible indication of service system messages, for example an end of the scanning process or error.

Special application: scientific research and animal blood studies (option).

“Hot” keys, masks, quick preview, color marks and comments for captured cells in the sample. Drag&Drop feature.

Quality control assesses correctness of blood smear preparation and functions of the system.

Detection control to assess leucocyte distribution and quality of sample preparation. “Show on slide” feature.

Autofocus.

Complete blood count form. Customizable reference guide to generate reports, following your personal requirements.

Report: information about laboratory, patient and analysis, WBC differential, images, erythrocytes, Price-Jones curve, identification of erythrocytes by size, color and shape, interpretation of results, comments, diagnoses, date and time and signature.

Report text templates — adjustable set of most commonly used text fields.

Data storage in the database, statistic handling, quick search, remote connection to the Internet and integration into other information networks (LIS/HIS).

Remote access and network capabilities. Connecting several working places to a remote server.

Walk Away mode. Scanning series of slides without continuous presence of the operator.

Random Access. Various scanning and analysis modes for each slide.

STAT testing. Testing of urgent samples.

Continuous slide loading mode. Loading slides in a queue during scanner operation. Organization of continuous process for blood cell image analysis.

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Vision Hema 1 Vision Hema 8 Vision Hema 200 Vision Hema Assist

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V-Sampler Instrument for preparation of standardized blood smears

— standardized process for blood smear preparation of high quality

— simultaneous preparation of 2 smears

— setting of thickness and size of the smear

— compact and lightweight

— simple and easy to use

Quality blood smear in 3 simple steps

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Place a drop of blood on the target area

Depress the lever carefully but firmly and release it

Get a clean, thin film containing a large area

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Ordering information

Description Code

Vision Hema 1 systemSet includes: MT5300M motorized trinocular microscope with specimen stage for 1 slide, Vision digital camera, Vision Hema software, PC and monitor.

70.0101.02

Vision Hema 8 systemSet includes: Zeiss AxioScope motorized trinocular microscope with specimen stage for 8 slides, Vision digital camera, Vision Hema software, PC and monitor.

70.8101.00

Vision Hema 200 systemSet includes: Zeiss AxioImager motorized trinocular microscope with specimen stage, autoloader for 200 slides, Vision digital camera, automated oil dispenser, barcode reader, barcode label printer, Vision Hema software, PC and monitor.

70.2101.01

Vision Hema AssistSet includes: MT4300M motorized trinocular microscope with specimen stage for 1 slide, Vision digital camera, Vision Hema Assist software, PC and monitor.

70.0106.00

Additional

V-SamplerInstrument for preparation of standardized blood smears.

80.0001.00

Automated oil dispenser 80.0006.00

Barcode reader 80.0004.00

Barcode label printer 80.0005.00

VISION HEMATOLOGY

Title

www.vision-at.com

WEST MEDICAFranz-Siegel-Gasse 12380 Perchtoldsdorf, Austriatel.: +43 (1) 804 81 84fax: +43 (1) 804 81 85vienna@westmedica.com

Official distributor

We reserve the right to change specification without notice.

Rev 4.1/10.2012 EN