reviewers, volume 10 (1996)
TRANSCRIPT
Reviewers, Volume 10" (1996) The editors would like to thank the Editorial Board and the following scientists who were kind enough to review papers and provide advice during 1996.
*From October 18, 1995 to October 17, 1996
Adler, Paul Allshire, Robin Ah, Fred Alwine, James Ammerer, Gustave Anderson, David Anderson, Kathryn Anderson, Phillip Andrews, Brenda Ares, Manuel Amdt, Kim Artavanis-Tsakonas,
Spyridon Artzt, Karen Ashburner, Michael Austin, Stuart Ausubel, Frederick Avery, Leon Avner, Philip Baker, Tania Baldwin, Albert, Jr. Baltimore, David Bannerjee, Utpal Banuett, Flora Barbacid, Mariano Bardwell, James Bargmann, Cori Barlow, Denise Barres, Barbara Bartolomei, Marisa Barton, Mary K. Basler, Konrad Bate, Michael Beach, David Beato, Miguel Becker, Peter Beddington, Rosa Beggs, Jean Behringer, Richard Bell, Steve Benezra, Robert Benson, Spencer Berget, Susan Berk, Arnold Bemards, Rene Bernstein, Alan Berry, Marla Besmer, Peter Beug, Hartmut Bickmore, Wendy Bienz, Marianne Bier, Ethan Bingham, Paul Bird, Adrian
Bishop, Douglas Black, Douglas Blackwell, Keith Blobel, Gunter Blumenthal, Thomas Bock, August Bodmer, Rolf Boeke, Jeff Bohmann, Dirk Bolen, Joseph Botchan, Michael Bothwell, A1 Bouck, Noel Brady, Scott Brandriss, Marjorie Bravo, Rodrigo Brent, Rodger Brewin, Nick Brockdroff, Neil Buckingham, Margaret Buratowski, Stephen Burden, Steven Burgoyne, Paul Burley, Stephen Butler, Mark Cantley, Lewis Capecchi, Mario Carey, Michael Carlson, Marian Carr, Anthony Carroll, Sean Cashmore, Tony Cedar, Howard Chandler, Vicki Chant, John Chater, Keith Chen, Jasmine Cho, Ken Chorey, Joanne Clayton, David Cleary, Michael Coen, Donald Coffin, John Cole, Charles Collins, Kathy Cooley, Lynn Corces, Victor Corey, Suzanne Costantini, Frank Courey, Albert Crabtree, Gerald Craig, Elizabeth Craig, Nancy Cross, Frederick Damsky, Caroline Dangl, Jeff Darnell, James Darnell, Robert Davies, Kay de Lange, Titia Deng, Xiong-W DeRobertis, Eddy Desplan, Claude Dixit, Vishva
Donahue, Thomas Donehower, Lawrence Draetta, Giulio Dreyfuss, Gideon Driever, Wolfgang Drubin, David Duboule, Denis Dunn, Ashley Dunphy, William Dynlacht, Brian Dyson, Nicholas Dzierzak, Elaine Ebright, Richard Eisenman, Robert Elgin, Sally Elion, Elaine Emerson, Beverly Engel, Douglas Ephrussi, Anne Errington, Jeffrey Ewen, Mark Farmer, Stephen Fearon, Eric Felsenfeld, Gary Firtel, Richard Fishman , Mark Flavell, Richard Franke, Werner Frasch, Manfred Freedman, Len Freidberg, Errol Friend, Stephen Fuchs, Elaine Furuya, Masaki Gall, Joseph Galloway, Denise Geiduschek, Peter Gerace, Larry Gibbs, Clarence Gilman, Michael Glass, Christopher Glover, David Gober, James Goff, Stephen Gold, Lawrence Goldfarb, Mitchell Goldstein, Joseph Goodman, Richard Gordon, Colin Gorovsky, Martin Gottschling, Daniel Grabowski, Paula Gralla, Jay Graves, Barbara Green, Michael Greenblatt, Jack Greenwald, Iva Greider, Carol Gridley, Thomas Griep, Anne Groner, Bernard Grossman, Alan Grummt, Ingrid Grunstein, Michael
GENES & DEVELOPMENT 3219
Gruss, Peter Guthrie, Chris Haber, lames Hahn, Steven Hake, Sarah Hall, Alan Hanahan, Doug Hannon, Gregory Hannun, Yosef Hargreaves, lohn Harper, Wade Harrison, Stephen Hartenstein, Volker Haselkorn, Robert Hauschka, Stephen Hawley, Scott Hayday, Adrian Hearing, Patrick Hengartner, Michael Henikoff, Steve Hernandez, Nouria Herskowitz, Ira Higgs, Doug Hill, Robert Hinnebusch, Alan Hinton, Barry Hirano, Tatsuya Hoch, James Hoeijmakers, lan Hoffman, Michael Hogan, Brigid Holder, Nigel Holmgren, Robert Hope, Ian Howley, Peter Hoyt, Andrew Hughes, Steve Hunter, Tony Hurt, Edward Hurwitz, lerard Hyman, Linda Hynes, Richard Ihle, James Ingraham, Holly Ish-Horowicz, David Jacks, Tyler Jackson, Ian Jackson, Stephen lacobson, Alan lackle, Herbert Jaenisch, Rudolph Jentsch, Stefan lessen, Kristijian Johnson, Gary Johnson, Peter Johnson, Reid Johnston, Lee Johnston, Mark Jones, Katherine loyner, Alexandra lurgens, Gerd Kahmann, Regine Kalderon, Dan Kaplan, Jerry Karpen, Gary Kastan, Michael
Kaufman, Paul Keller, Walter Kenyon, Cynthia Kessin, Richard Kidwell-Brown, Margaret Kim, Stuart Kimelman, David Kimmel, Alan Kimmel, Charles Kingsley, David Kingston, Robert Kintner, Christopher Klein, Hannah Kolodner, Richard Konderosi, Adam Konopka, James Koopman, Peter Korsmeyer, Stanley Kowalcykowski, Stephen Krainer, Adrian Krasnow, Mark Krumlauf, Robb Kustu, Sydney Lamond, Angus Landy, Art Lane, Daniel Lane, David Lassar, Andrew Lazenbnik, Yuri Leavitt, Andrew Leder, Phil Lee, David Lees, Jackie Lehmann, Alan Lehner, Christian Lemke, Greg Leptin, Maria Levin, David Levine, Arnold Levy, David Lewis, Susanna Lis, John Losick, Richard Lovell-Badge, Robin Lowe, Scott Lowry, Douglas Luhrmann, Reinhard Lustig, Art Lyon, Mary Maas, Richard MacDonald, Paul MacLeod, K. Maizels, Nancy Mak, Tak Malim, Michael Mangelsdorf, David Maniatis, Tom Mann, Jeffrey Marshall, Chris Martin, David Massague, Joan Mathews, Michael Mattaj, Iain Matthias, Patrick Meinke, David Melton, Doug
Mendenhall, Michael Miller, Lois Mirsky, Rhona Mitchell, Aaron Mizuuchi, Kiyoshi Mlodzik, Marek Model, Peter Modolell, Juan Mohun, Tim Moon, Randall Moore, Melissa Morimoto, Richard Moses, Harold Moses, Kevin Moss, Tom Murray, Andrew Murre, Cornelius Nabel, Gary Nasmyth, Kim Neuberger, Michael Neufeld, Elizabeth Nevins, Joseph Newlon, Carol Newman, Andrew Newport, John Nilsen, Timothy Niswander, Lee Nomura, Masayasu Nurse, Paul Nusse, Roel O'Farrell, Patrick Olson, Eric Oren, Moshe Orkin, Stuart Orr-Weaver, Terry Pabo, Carl Pace, Norman Parker, Malcolm Parker, Peter Parker, Roy Parkinson, Sandy Paro, Renato Parslow, Tristan Pavletich, Nikola Pendergast, Ann Marie Perlman, Philip Perlmann, Thomas Perrimon, Norbert Peterson, Craig Pfahl, Magnus Phillips, Simon Pillus, Lorraine Poellinger, Lorenz Polakis, Paul Posakony, James Priess, James Pringle, John Proudfoot, Nicholas Ptashne, Mark Pugh, B. Franklin Quail, Peter Rabbitts, Terry Raff, Martin Rajewsky, Klaus Ramakrishnan, Venki Reed, Robin
3220 GENES & DEVELOPMENT
Reed, Steve Reeder, Ronald Reik, Wolf Reinberg, Danny Reines, Daniel Reznikoff, William Rice, Andrew Rigby, Peter Rine, Jasper Rio, Donald Roberts, James Robertson, Elizabeth Roeder, Robert Rong, Li Roop, Dennis Rorschneider, Lawrence Rosbash, Michael Rose, Mark Rosenberg, Naomi Rosenfeld, M. Geoff Rossant, Janet Rushlow, Christine Russell, Marjorie Russell, Paul Ruvkun, Gary Rymond, Brian Sachs, Alan Sandmeyer, Suzanne Sanes, Josh Sarnow, Peter Schechter, Alan Schedl, Andreas Schedl, Paul Schedl, Timothy Schlessinger, Joseph Sch6pbach, Trudi Schwab, Martin Schwarz-Sommer,
Zsuzsanna Scott, Matthew Semenza, Gregg Shackleford, Gregory Shilo, Ben-Zion Shimkets, Lawrence Shimura, Yoshiro Shore, David Siebenlist, Ulrich Sigler, Paul Silhavy, Thomas Silver, Pamela Simons, Kai Simpson, Patricia Simpson, Robert Singh, Harinder Sive, Hazel Skene, Barbara Skowronski, Jacek Slack, Jonathan Smale, Steven Smith, Jim Smith, Mitchell Snyder, Michael Sollner-Webb, Barbara Sorger, Peter Speck, Nancy Speigelman, Bruce
Spradling, Allan Sprague, George St. Johnston, Daniel Stadtman, Theresa Stark, Mike Staskawicz, Brian Stellar, Hermann Stenlund, Arne Sternberg, Paul Sternglanz, Rolf Stillman, Bruce Strasser, Andreas Strickland, Sidney Struhl, Gary Struhl, Kevin Studer, Michelle Stunnenberg, Henk Surani, Azim Tessier-Lavignc, Marc Thomas, Christopher Thompson, Craig Thummel, Carl Tollervey, David Tomlinson, Andrew Treisman, Richard Tryggvason, Karl Tye, Bik-Kwoon Ullu, Elizabetta Van Aelst, Linda Van Dyke, Terry van Heyningen, Veronica Varmus, Harold Vennstrom, Bjom Verma, Inder Vogt, Peter Wagner, Erwin Wahl, Geoffrey Walbot, Virginia Wasserman, Steven Weber, Klaus Weigel, Detlef Weinberg, Robert Weinert, Ted Weissman, Charles Weissman, irving Wensink, Peter West, Stephen Westerfield, Monte Weston, Kathleen White, Eileen White, Rob Wickens, Marvin Wieczorck, Helmut Wieschaus, Eric Willison, Keith Winston, Fred Wisniewski, Henryk Witte, Owcn Wolffe, Alan Wong, Winnie Wood, Richard Wormington, Michael Wright, Christopher Yamamoto, Keith Yanagida, Mitsuhiro Yaniv, Moshe
Yanofsky, Martin Young, Richard Yuspa, Stuart Zakian, Virginia Ziff, Edward Zinn, Kai
GENES & DEVELOPMENT 3221
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3222 GENES & DEVELOPMENT
Author Index, Volume 10 (1996) Abrams, J.M., 1773 Adams, J.M., 70 Adler, H.8., 1455 Aebersold, R., 1084 Aguilar-Cordova, E., 553 Ahringer, J., 1120 Akimani, H., 528 Alarcon, C.M., 279 Alexandre. C., 2003 Alexandropoulos, K., 1341 Algate, P.A., 1084 Allende, M.L., 3141 Alley, M.R.K., 1532 Alwine, J.C., 325, 1369 Alzhanova-Ericsson, A.T.,
2881 Amano, S., 1724 Amberg, D.C., 1608 Ammerer, G., 129 Amsterdam, A., 3141 Anderson, J.E., 1173 Andresen, J.M., 2903 Andrew, D.J., 103 Apone, L.M., 2368 Arber, S., 289 Ares, M., Jr., 220 Arndt, K.T., 1904 Arroyo, E., 1751 Asano, M., 1422 Ashley, T., 2411, 2423 Assa-Munt, N., 16 Aubry, L., 118 Azpiazu, N., 3183 Badiani, P., 2732 Bagni, C., 1411 Bai, Y., 2025 Baker, J.C., 1880 Baltimore, D., 963, 1341,
2401, 2411 Banerjee, U., 1194 Barberis, A., 2359 Bardwell, L., 2831 Barolo, S., 3195 Barrett, T., 2732 Basson, M., 1953 Baumeister, R., 1395 Beach, D., 1633 Beall, E.L., 921 Beard, C., 1008 Beaulieu, N., 1930 Becker, T., 3141 Behringer, R.R., 2577 Beijersbergen, R.L., 2969 Beiman, M., 2993 Belfort, M., 351, 2158 Bentley, N.J., 2423 Berget, S.M., 208 Bergstrom, D.E., 1260 Berk, A.J., 2491 Bermingham, J.R., Jr., 1751 Bemards, R., 2969 Beug, H., 2462 Biehs, B., 2922 Bier, E., 2922
Birchmeier, C., 1184 Bitgood, M.J., 647 Blackburn, E.H., 1822 Blackman, R.K., 1260 Blakely, G., 762 Blatter, E.E., 16 B6hm, T., 1516 Boeke, J.D., 620 Bogue, M.A., 553 Boise, L.H., 2621 Bommakanti, M., 129 Bonten, E., 3156 Boscheron, C., 1796 Bossard, P., 1670 Bouhidel, K., 1812 Bowman, T., 826 Braincrd, E.E., 2411, 2423 Brass, A.L., 2335 Breitwieser, W., 2179 Brewer, B.J., 1595 Brill, S.J., 2222 Brissette, J.L., 2212 Broach, J.R., 382, 1021 Brodbeck, C., 2707 Brody, M.S., 2265 Bronson, R.T., 1621, 1633,
2055, 2411 Brook, A., 2505 Brown, J.D., 2805 Brown, S.A., 1479 Brun, R.P., 974 Bryant, G.O., 2491 Brzoska, P.M., 2564 Buck, S.W., 1297 Bullrich, F., 1724 Bunker, C.A., 905 Burgeson, R.E., 1724 Burke, T.W., 711 Burley, S.K., 2491 Burson, L.M., 887 Cairns, B.R., 2117, 2131 Camper, S.A., 313 Cannon, K., 37 Cao, J., 1049 Cao, Z., 37 Cardenas, M.E., 279 Carey, M., 2540, 2769 Carlberg, K., 1084 Carlson, M., 3105 Caroni, P., 289 Cart, A.M., 2423 Carthew, R.W., 2167 Castaho, I.B., 2564 Cate, R.L., 2577 Cech, T.R., 2870 Cepek, K.L., 2079 Chambon, P., 80, 2326 Chan, Y.R., 2055 Chang, H.C., 272 Chang, J., 777 Chao, D.T., 2859 Chasman, D.I., 2079 Chen, H., 2564 Chen, J., 974
Chen, J.-Y., 2326 Chen, P., 1773 Chen, P.-L., 2794 Chen, X., 2438 Chen, Y., 2794 Cheng, G., 963 Chi, T., 2540 Chin, W., 80 Chin-Sang, I.D., 2314 Christenson, E.R., 2423 Christiano, A.M., 1724 Christman, M.F., 2564 Chung, D., 3051 Clark, A.M., 118 Clarkin, K.C., 934 Cleghon, V., 566 Clurman, B.E., 1979 Clyman, J., 351 Cobrinik, D., 1633 Cocker, J.H., 1516 Coffer, P., 1455 Cohen, J.B., 338 Cohen, M., 129 Cohen-Fix, O., 3081 Cole, C.N., 1608 Coleman, J.R., 1670 Colot, H.V., 1699 Cook, J.G., 2831 Copeland, T.D., 566 Cornet, F., 1152 Cosgrove, D., 2981 Costantini, F., 154 Coursen, J.D., 1219 Crabtree, G.R., 2117 Craig, N.L., 2145 Crespo, P., 1455 Crompton, T., 948 Cygan, J.A., 1260 Daga, A., 1194 D'Agati, V.; 154 Dahanukar, A., 2610 Dai, P., 528 Damania, B., 1369 Daneholt, B., 2881 Danska, J.S., 2038 Darlington, G.J., 804 Dash, A.B., 1858 Datar, S.A., 1966 Dausman, J., 1008 Davis, R.J., 2732 d'Azzo, A., 3156 De Baere, I., 755 Decimo, D., 80 DeArmond, S.J., 1736 DeBoy, R.T., 2145 Decatur, A.L., 2348 Degenstein, L., 165 Deng, K., 1657 Denis, G.V., 261 Desbarats, L., 447 Devine, S.E., 620 Di Como, C.J., 1904 Di Cunto, F., 3065 Di Leonardo, A., 934
Dierich, A., 80 Diffley, J.F.X., 1516, 2819 Diller, J.D., 1595 Dodd, J.A., 887, 2551 Doe, C.Q., 3003 Doherty, D., 421 Dominski, Z., 3028 Donaldson, T., 2302 Donehower, L.A., 553 Dotto, G.P., 2212, 3065 Doucas, V., 196 Drouin, J., 1284 Du, W., 1206 Duboule, D., 2326 Dudek, H., 816 Dugich-Djordjevic, M.M.,
3129 Dull, M., 1382 Dumstrei, K., 1194 Dunphy, W.G., 1503 Duronio, R.J., 2505 Dyson, N., 1206, 1621, 1633,
2505 Eady, R.A.J., 1724 Eagelson, K., 1049 Ebright, R.H., 16 Eckhaus, M., 836 Eckner, R., 2478 Edgar, B.A., 1966 Edmondson, D.G., 1247 Eichele, G., 176 Eidemiller, J., 185 Eilers, M., 447 Eisenbeis, C.F., 2335 Elledge, S.J., 2632 Ellis, R., 974 Elmore, L., 1219 Endo, S., 1645 Ephrussi, A., 2179 Erdjument-Bromage, H., 1049 Errington, J., 794 Evans, R.M., 196, 974 Fangman, W.L., 1595 Fankhauser, C., 2707 Fantino, E., 887 Farihas, I., 1382 Farrell, S., 2359 Fay, D.S., 395 Feger, G., 421 Feld, R., 244 Ferguson, B.M., 1595 Ferguson, K.C., 1543 Fernandez-Salguero, P., 60 Feucht, A., 794 Field, D.J., 489 Fiering, S., 185 Filosi, N., 407 Finegold, M.J., 2577 Firtel, R.A., 118 Fischer, D., 1143 Fisher-Adams, G., 686 Fitzsimmons, D., 2198 Flaggs, G., 2423 Flesken-Nikitin, A., 1835
GENES & DEVELOPMENT 3223
Foiani, M., 395 Forman, B.M., 974 Fornerod, M., 3156 Forrester, K., 1219 Fox, C.H., 60 Frampton, J., 2720 Francois, V., 2922 Frasch, M., 3183 Fraser, P., 2894 Fredericks, W.J., 2067 Freedman, L.P., 129 Friedman, J.R., 2067 Friedman, K.L., 1595 Friend, S., 2382 Friesen, J.D., 489 Fritz, A., 2759 Fuchs, E., 165 Gaal, T., 16 Gaget, R.F., 208 Gaiano, N., 3141 Galceran, J., 1382 Gallagher, P.A., 2167 Gallie, B.L., 3051 Gansmuller, A., 80 Garrett, K., 1173 Gaskins, C., 118 Gasser, S.M., 1796 Gaubatz, S., 447 Gauthier, Y., 1284 Gayko, U., 566 G6rard, M., 2326 Geiduschek, E.P., 725 Gibson, M., 1219 Gilson, E., 1297, 1796 Girard, L., 1930 Gish, B., 1773 Gisselbrecht, S., 3003 G6mez-Skarmeta, J.L., 2935 G6decke, S., 1184 Godley, L.A., 836 Gonzalez, F.J., 60 Goodrich, L.V., 301 Gordon, J.I., 985 Gotta, M., 1796 Gourse, R.L., 16 Gozani, O., 244 Graf, T., 2720 Grallert, B., 2644 Grandal, I., 2038 Gray, S., 700 Greco, T.L., 313 Green, M.R., 261, 517, 2368 Gribnau, J., 2894 Grisham, J., 245 Grondona, J.M., 80 Gronemeyer, H., 2326 Gross, C.A., 3170 Grosschedl, R., 1382 Grossman, A.D., 2014 Grosveld, F., 2894 Grosveld, G., 3156 Groudine, M., 185, 1979 Grumbling, G., 2302 Grunkemeyer, J.A., 2981 Grunstein, M., 686, 1327 Gruszynski-DeFeo, E., 672
Gu, C., 2222 Gu, L., 826 Gualdi, R., 1670 Guermah, M., 2389 Guidos, C., 2038 Guo, L., 165 Gutkind, J.S., 1455 Ha, I., 3041 Haag, T.A., 672 Hacohen, N., 2912 Hafen, E., 2759 Haga, T., 1736 Hagman, J., 2198 Hagstrom, K., 3202 Hamada, Y., 1670 Hamer, J.E., 2696 Hammerschmidt, M., 647,
2452 Han, J., 461 Han, Z., 2732 Hanahan, D., 2105 Hanna, Z., 1930 Hannon, G., 1633 Hansen, S.K., 2903 Hara, Y., 60 Harkness, T.A.A., 686 Harland, R.M., 1880 Harlow, E., 1621, 1633 Harper, J.W., 1491 Harris, A.W., 2055 Harris, C.C., 1219 Hartenstein, V., 672 Hartley, L., 70 Harvey, R.P., 70 Hateboer, G., 2969 Hatini, V., 1467 Hawley, R.S., 2383 Hayashi, S., 659 Hayday, A.C., 948 Haynes, M., 220 Hazel, T.G., 3129 He, T.-C., 1945 Heid, p.J., 1543 Heintz, N., 2389 Heitman, J., 279 Henderson, D.W., 1455 Hengge-Aronis, R., 1143 Henry, M., 1233 Hentsch, B., 70 Hermiston, M.L., 985 Herzlinger, D., 1467 Hill, R.E., 435 Hinman, A., 2971 Hogaard, A., 1162 Hodsdon, W., 2198 Hoeijmakers, J.H.J., 1219 Hoekstra, M.F., 2423 Hoemann, C., 1930 Hoffman, E.S., 948 Hoffmann, A., 2389 Hofmann, F., 851, 2949 Hogan, B.L.M., 1580, 1657 Holmes, S.G., 1021 Holtzman, D.A., 2423 Hopkins, N., 3141 Hopper, A.K., 1608
3224 GENES & DEVELOPMENT
Hoppler, S., 2805 Horstmann, H., 2179 Horvitz, H.R., 578, 1073,
1289, 1953 Hou, D.-X., 528 Hsu, T., 1411 Hu, M.C.-T., 2251 Huang, E., 1433 Huang, M.T.F., 2038 Huang, X.-P., 2067 Huang, Y.-J., 351 Hudson, D.L., 1724 Huh, S.O., 1467 Hunter, W.J., 2981 Hwang, D.-Y., 338 Igel, H., 220 Imbalzano, A.N., 905, 1479 Ingham, P.W., 2003 Ingledue, T.C., III, 3028 Inostroza, J.A., 1049 Ip, Y.T., 2732 Irish, V.F., 1812 Isaac, D.D., 103 Ishii, S., 528 Ishov, A.M., 196 Izaurralde, E., 1683 Jacinto, A., 2003 Jacks, T., 1621, 1633, 2055 Jackson-Grusby, L., 1008 Jaenisch, R., 1008, 1991 Jallepalli, p.v., 541 Jan, L.Y., 421 Jan, Y.N., 421 Jarmolowski, A., 1683 Jayaraman, L., 2438 Jenni, M., 2759 Jensen, D.E., 2067 Jia, X., 16 Jiang, R., 3105 Jiang, Y.W., 604 Jiang, Z., 3051 Joazeiro, C.A.P., 725 Johe, K.K., 3129 Johnson, R.C., 2769 Johnson, R.L., 301 Jolicoeur, P., 1930 Jones, K.A., 37 Jones, N., 2289 Josso, N., 2577 Joyner, A.L., 3077 Juguilon, H., 196 Kablar, B., 1173 Kadonaga, J.T., 37, 711 Kadowaki, T., 3116 Kafatos, F.C., 1411 Kaiser, D., 740 Kalla, K.A., 1751 Kamimura, J., 2212 Kane, M.F., 407 KaneioIshii, C., 528 Kang, C.M., 2265 Karim, F.D., 272 Karlovich, C.A., 1194 Karrim, J., 2105 Kassavetis, G.A., 725 Kassis, J., 1108
Kastner, P., 80 Kataoka, Y., 659 Kauffmann, R.C., 2167 Kaufman, T.C., 176 Kaufmann, J., 873 Kawakami, K., 3141 Ke, N., 634 Keck, J.G., 37 Keegan, K.S., 2423 Kehrli, E., 2335 Kelly, T.J., 541 Kerkhoven, R.M., 2969 Kerr, K., 2600 Keys, D.A., 887, 2551 Kieser, A., 1455 Kim, J.B., 1096 Kim, J.M., 634 Kimelman, D., 1433 Kimsey, H., 740 Kimura, S., 60 Kingston, R.E., 905, 1479,
2782 Kinzler, K., 1945 Kirschner, M.W., 3081 Kiseleva, E., 2881 Kiyokawa, H., 3065 Klein, R., 2849 Klemm, J.D., 27 Klingensmith, J., 3116 Knauf, U., 2782 Knight, S.A.B., 1917 Knowles, G., 2038 Ko, L.J., 1054, 2438 Kobayashi, M., 1783 Koch, C., 129 Koff, A., 948, 3065 Kojima, T., 1645 Kolch, W., 1455 Kolodner, R., 407, 1433 Kondo, K., 1783 Kopp, J.B., 836 Kornak, J.M., 2981 Kornberg, R.D., 2131 Korsmeyer, S.J., 2859 Koshland, D., 3081 Kosman, D.J., 1917 Kowalczykowski, S.C., 1890 Kozak, C.A., 1930 Krall, L., 245 Krasnow, M., 2912 Kratochwil, K., 1382 Kraut, R., 659 Kremmer, E., 1455 Krezel, W., 80 Krishnan, V.V., 16 Kron, S.J., 2831 Kuempel, P., 1162 Kuo, A., 2117 Kwon, L.F., 1917 Kwon, Y.T., 816 Kyriakis, J., 2782 Labb6, S., 1917 Labosky, P.A., 1657 Lagrange, T., 2657 Lai, E., 1467 Laird, P.W., 1008
Lamonerie, T., 1284 Lanct6t, C., 1284 Landsman, D., 1049 Lane, E.B., 1724 Lawrence, P.A., 3183 Lazazzera, B.A., 2014 Lee, B.-S., 887 Lee, D., 2212 Lee, M.-H., 129, 1621, 1633 Lee, M.S., 1233 Lee, T., 2912 Lee, W.-H., 1835, 1870, 2794 Lehmann, R., 3077 Lei, H., 1008 Leid, M., 80 Leigh, I.M., 1724 Leng, X., 1491 Leu, T.M.J., 948 Levin, P.A., 478 Levine, A.J., 2971 Levine, M., 700, 3195 Levinson, R.S., 2131 Levitt, P., 1049 Lewis, J.D., 1683 Li, B., 1310 Li, E., 1008 Li, J., 2212 Li, R., 70 Li, S., 1835 Li, S., 2167 Li, X.-Y., 517 Liaw, L., 1657 Lilly, M.A., 2514 Lim, S.-K., 154 Lin, C.-S., 154 Ling, X., 686 Linke, S.P., 934 Lints, T.J., 70 Lioubin, M.N., 1084 Liu, C.-Y., 1835 Liu, M., 129 Liu, X.-D., 592 Liu, Y., 1395 Livingston, D.M., 851, 2478,
2949 Lobel, L., 2189 Losick, R., 478, 2348 Lou, H., 208 Louarn, J., 1152 Louarn, J.-M., 1152 Lowell, C.A., 1845 Lu, H.-C., 176 Lu, J., 2222 Lu, Q., 1327 Lundblad, V., 3094 Lupold, S.E., 1219 Lustig, A.J., 1310 Lutz, B., 176 Lutz, C.S., 325 Lynch, K.W., 2089 Lyons, I., 70 Ma, X.-J., 1327 Macdonald, P.M., 2600 Madden, K., 777 Magis, W., 185 Magnin, T., 794
Maillet, L., 1796 Maira, S.-M., 2198 Majerus, P.W., 1051 Maniar, H.S., 2222 Maniatis, T., 1356, 2089 Manley, J.L., 325, 862, 1569,
2588 Marcand, S., 1297, 1796 Marini, F., 395 Mark, M., 80 Markussen, F.-H., 2179 Marsischky, G.T., 407 Martel, L.S., 2491 Martelli, F., 2949 Marth, J.D., 3051 Martin, D.I.K., 185 Marzluff, W.F., 3028 Matsui, W., 1271 Mattaj, I.W., 1683 Matzuk, M.M., 2577 Maul, G.G., 196 McEachern, M.J., 1822 McGonigle, B., 1812 McGrath, J.A., 1724 McGuigan, C., 1683 McKay, R.D.G., 3129 McKnight, S.L., 367 McLean, W.H.I., 1724 McMahon, A.P., 313, 647,
2452 McMahon, J.A., 301,313 McMillan, J.R., 1724 Meehan, D.T., 2981 Megeney, L.A., 1173 Mellerick, D.M., 1108 Merli, C., 1260 Mermelstein, F., 1049 Meyer, C.F., 2251 Meyn, M.S., 2411, 2423 Michaud, N.R., 2684 Michelson, A.M., 3003 Milenkovic, L., 301 Millar, J.B.A., 2289 Miller, D., 176 Miller, J.R., 1433, 2527 Milliman, C.L., 2859 Minichiello, L., 2849 Minn, A.J., 2621 Mischak, H., 1455 Mishina, Y, 2577 Missero, C., 3065 Mitchell, P., 502 Miyake, T., 1783 Mlodzik, M., 50 Modha, D., 461 Modolell, J., 2935 Montell, D.J., 2912 Moon, R.T., 1433, 2527, 2805 Moose, S.P., 3018 Moretti, P., 1297 Morris, D.K., 3094 Morrison, D.K., 566, 2684 Moss, S.B., 2423 Mueller, J.E., 351, 2158 Muffler, A., 1143 Mukai, S., 1621
Mullen, J.R., 2222 Muller, M., 3202 Muller, T., 3129 Mulligan, G., 1621, 1633 Murayama, A., 1783 Murphy, M., 2971 Murthy, K.G.K., 325 Mushinski, J.F., 1455 Nacht, M., 2055 Nagappan, O., 1162 Naik, P., 2105 Nakanishi, M., 804 Nasmyth, K., 129, 1516 Navas, T., 2632 Neilson, E.G., 2067 Ness, S.A., 1858 Neville, M., 220 Nevins, J.R., 1422 Newhouse, M.W., 313 Newton, E.M., 2782 Nguyen, T.T., 887 Nickels, J.T., 382 Nielsen, M., 1162 Nikitin, A.Yu, 1870 Nikolic, M., 816 Nogi, Y., 887 Nomura, M., 887, 2551 Nordstrom, W., 1773 Norris, I.L., 862 Nuez, B., 2894 Nurse, P., 2644 Nyland, S.V.M., 1595 O'Connell, S., 1751 O'Connor, J.P., 325 Oda, H., 659 Odenwald, W.F., 1108 O'Farrell, P.H., 2505 Oft, M., 2462 Ohno, M., 997 Olde, B., 1108 Oldread, E., 2478 Oliner, J.D., 2903 Omatyar, L., 672 Oren, M., 826 Orphanides, G., 2657 Orrico, F.C., 1858 Owaribe, K., 1724 Owen, M.J., 948 Owens, J., 836 Pabo, C.O., 27 Paglino, J.J., 836 Panning, B., 1991 Parker, M.M., 351 Parker, S.B., 1491 Passoni, L., 948 Patra, D., 1503 Patte, J., 1152 paull, T.T., 2769 Pazin, M.J., 37 Peli, J., 2462 Perez, D., 461 Perkins, L.A., 566 Perrimon, N., 566, 3116 Peters, J.-M., 3081 Petfalski, E., 502 Philipova, D., 2222
Philipsen, S., 2894 Phillips, R.A., 3051 Piatti, S., 1516 Pineau, T., 60 Plasterk, R.H.A., 755 Plug, A.W., 2423 Polyak, K., 1945 Powell, F.L., 1751 Price, C.W., 2265 Pritchard, D.K., 1131 Prives, C., 1054, 2438 Prusiner, S.B., 1736 Ptashne, M., 2359 Pulkkinen, L., 1724 Qiu, W.R., 2251 Quinn, J.C., 435 Ramos, Y.F.M., 816 Ramqvist, T., 2720 Rao, L., 461 Rauscher, F.J., iii, 2067 Ray, R.P., 1711 Reed, R., 244 Reese, J.C., 2368 Reichmann, E., 2462 Reinberg, D., 1049, 2657 Rey, R., 2577 Riesgo-Escovar, J.R., 2759 Riethmacher, D., 1184 Riley, D.J., 2794 Rio, D.C., 921 Roberts, J.M., 1979 Roeder, R.G., 2389 Roemer, T., 777 Rohrschneider, L.R., 1084 Romo, A., 196 Rosbash, M., 1699 Rosenfeld, M.G., 1751 Ross, W., 16 Roth, D.B., 553 Roth, S.Y., 1247 Rothman, J.H., 1543 Rouvi6re, P., 3170 Rubin, G.M., 272, 2684 Rudaz, C., 2462 Rudnicki, M.A., 1173 Rugg, E.L., 1724 Rusconi, C.P., 2870 Russell, P., 2276 Ruvkun, G., 1395, 3041 Saavedra, C., 1608 Sabbatini, P., 461 Sadoff, B.U., 2564 Sager, B.M., 2237 Saigo, K., 1645 Samuels, M., 2289 Samuelson, G.C., 2981 Sanchez, Y., 2632 Sawa, H., 2189 Sayers, R., 2981 Scalzo, D., 185 Schatz, D.G., 948 Schedl, P., 3202 Schek, N., 325 Scherer, S.S., 1751 Schier, A.F., 3077 Schleiffer, A., 129
GENES & DEVELOPMENT 3225
Schlissel, M., 2055 Schneider, R.J., 1557 Schnepp, B., 2302 Schiipbach, T., 1711 Schubiger, G., 1131 Schultz, M.C., 686 Schwarz, H., 2462 Scott, M.P., 301 Segall, J.E., 118 Segil, N., 2389 Seicher, D.W., 2067 Seitz, T., 1455 Serbedzija, G.N., 2452 Shaham, S., 578, 1073 Shao, J., 873 Shapiro, L., 1532 Sharp, P.A., 2079 Sheaff, R.J., 1979 Sheridan, P.L., 37 Sherratt, D., 762 Shieh, J.-C., 2289 Shilo, B.-Z., 93, 2993 Shimura, Y., 997 Shiozaki, K., 2276 Shore, D., 1297 Shvarts, A., 2969 Silver, P.A., 1233 Simanis, V., 2707 Simard, C., 1930 Simcox, A., 2302 Simkovich, N., 2359 Singh, H., 2335 Sisco, P.H., 3018 Skeath, J.B., 3003 Slack, F.J., 740 Sluss, H.K., 2732 Smale, S.T., 873 Smibert, C.A., 2600 Smith, D., 2158 Smith, F.J.D., 1724 Smith, J.R., 804 Smith, M.M., 1247 Snyder, M., 777 Sogaard-Andersen, L., 740 Soares, V.C., 1467 Sohrmann, M., 2707 Solomon, J.M., 2014 Solomon, N.M., 272 Sonnenberg-Riethmacher, E.,
1184 Soriano, P., 1845 Spence, A.M., 2314 Spiegelman, B.M., 974, 1096 Spradling, A.C., 2514 St-Arnaud, R., 1763 Starr, D.B., 1271 Steffan, J.S., 2551 Stepanova, L., 1491 Stephens, C., 1532 Stern, D.F., 395 Stillman, D.J., 604 Storb, U., 2335 Strasser, A., 2055 Stutz, F., 1699 Sun, X., 2881 Sun, Z., 395
Sutherland, J.D., 1411 Suzuki, T., 1783 Symington, L.S., 2025 Symonds, H., 826 Szymanski, P., 3195 Tacke, R., 1569 Takada, S., 313 Takagaki, Y., 2588 Takahashi, F., 1645 Takahashi, T., 528 Takahisa, M., 1783 Takeda, T., 2289 Takeichi, M., 659 Talbot, W.S., 3077 Tan, T.-H., 2251 Tanaka, Y., 528 Tang, H., 16 Taylor, D., 2732 Taylor, E.M., 2423 Tecklenburg, M., 1162 Telling, G.C., 1736 Tempst, P., 1049 Tepass, U., 672 Therrien, M., 272, 1284, 2684 Thiele, D.J., 592, 1917 Thomas, J.R., 1271 Thompson, C.B., 2621 Thorner, J., 2831 Thress, K., 1979 Timchenko, N.A., 804 Tjian, R., 50, 2903 T6r6k, T., 672 Toda, T., 2289 Togashi, S., 1783 Tollervey, D., 502 Tontonoz, P., 974 Toone, W.M., 2289 Torchia, M., 1736 Torres, M., 1443 Tracy, R.B., 1890 Tremblay, J.J., 1284 Tremblay, P., 1736 Trimborn, T., 2894 Tsai, L.-H., 816 Tsai, S., 1084 Tsou, A., 934 Tucker, K.L., 1008 Tung, K.-S., 1608 Ueda, R., 1783 Uemura, T., 659 Uitto, J., 1724 van der Spoel, A., 3156 Van Dyke, T., 245, 826 Varmus, H.E., 836 Vermeulen, W., 1219 Verrijzer, C.P., 873 Vidal, M., 1206 Vincent, J.-p., 3183 Virbasius, C.-M.A., 2368 Virta-Pearlman, V., 3094 Visa, N., 2881 Vogelstein, B., 1945 Volk, T., 2993 Vos, J.C., 755 Voytas, D.F., 634 Vu, L., 887
Wade, M., 245 Wahl, G.M., 934 Waldman, T., 1945 Walter, B., 1184 Walters, M.C., 185 Wang, J., 220 Wang, l., 2588 Wang, K., 2859 Wang, W., 2117 Wang, X., 2251 Wang, X.W., 1219 Wang, Z., 2949 Wang, Z-F., 3028 Ward, J.M., 60 Wassarman, D.A., 272 Wasylyk, B., 2198 Weinberg, R.A., 1633 Weitzman, M.D., 196 Weizman, I., 93 Wells, S.E., 220 West, J.D., 435 Weston, K., 2732 Wharton, R.P., 1422, 2610 Wheat, W., 2198 White, E., 1,461 Whitfield, M.L., 3028 Wightman, B., 3041 Wijgerde, M., 2894 Wilde, M., 804 Wilder, E., 3116 Wilk, R., 93 Wilkinson, M.G., 2289 Williams, B.O., 1621 Williams, C.J., 2038 Wilson, J.E., 2600 Wolkow, C.A., 2145 Wong, M.H., 985 Wright, R., 1532 Wu, H., 245 Wu, Y., 2359 Wurtz, T., 2881 Xie, J.-E., 1206 Xiong, Y., 245 Xu, G., 1219 Xu, J.-R., 2696 Xu, Y., 2401, 2411 Xue, D., 1073 Xue, Y., 2117 Yamamoto, K.R., 1271, 2131 Yang, X., 2265 Yao, T.-P., 2478 Yasukawa, T., 528 Yeh, H., 1219 Yeung, K., 1049 Yin, C., 826 Yin, X.-M., 2859 Yokomori, K., 50 Yost, C., 1443 Yotov, W.V., 1763 Younger-Shepherd, S., 421 Yudkin, M.D., 794 Yueh, A., 1557 Zakany, J., 2326 Zachary, K., 3116 Zacksenhaus, E., 3051 Zaret, K.S., 1670
Zeidler, M.P., 50 Zeng, Y., 1835 Zhang, J., 2167 Zhang, S.-D., 1108 Zhao, G.-Q., 1657 Zheng, M., 1670 Zhou, J., 3195 Zhou, S., 2117, 2903 Zhu, C., 553 Zou, S., 634 Zuo, P., 1356 Zweiger, G., 1532
3226 GENES & D E V E L O P M E N T
Subject Index, Volume 10 (1996)
ACT3 gene, epigenetic effects on yeast transcription caused by muta- tions (Jiang and Stillman), 604- 619
Actin, LIM-mediated binding of MLP to cytoskeleton (Arber and Ca- roni), 289-300
Actin-related protein, epigenetic effects on yeast transcription caused by mutations (Jiang and Stillman), 604-619
Activating transcription factor-2 Spcl regulation of S. pombe homolog
Atfl (Shiozaki and Russell), 2276-2288
role of DNA-binding domain as inhib- itory region (Li and Green), 517- 527
Activation, transcriptional by aCTD-DNA interactions in E. coli
(Gaal et al.), 16-26 CBP as a coactivator of c-Myb (Dai et
al.), 528-540 cell-cycle regulation of SBF binding
(Koch et al.), 129-141 during Drosophila embryogenesis
(Pritchard and Schubiger), 1 1 3 1 - 1 1 4 2
functional TBP epitopes for Pol II ac- tivity (Bryant et al.), 2491-2504
inhibition by the ATF-2 DNA-binding domain (Li and Green), 517-527
regulation of transcriptional pausing on nucleosomal templates (Brown et al.), 1479-1490
role of TFIIA-TFIID complex forma- tion in gene activation (Chi and Carey), 2540-2550
specificity of Myc (Desbarats et al.), 447-460
Activators, gene-specific, findings pre- sented at Cold Spring Harbor meeting (McKnight), 367-381 Meeting commentary
Activin, participation of Madr2 in signal- ing pathway (Baker and Har- land), 1880-1889
Activity, context-dependent, altered in- tracellular receptor activation (Start et al.), 1271-1283
ADD1, role in adipocyte differentiation (Kim and Spiegelman), 1096- 1107
Adenine DNA methyltransferases, CcrM as target of Lon protease in C. crescentus (Wright et al.), 1532-1542
Adenovirus POD organization and viral DNA rep-
lication (Doucas et al.}, 196- 207
regulation of E2F degradation by trans-
forming proteins (Hateboer et al.), 2960-2970
use of ribosome jumping for transla- tion of late mRNAs (Yueh and Schneider), 1557-1567
Adhesion proteins, role of plx in tracheal function (Zhang et al.), 1108- 1119
Adipogenesis. See also Differentiation, adipocyte
differential activity of multiple PPAR isoforms (Brun et al.), 974-984
role of Rb interaction with C/EBPs in adipocyte terminal differentia- tion lChen et al.), 2794-2804
Adipose tissue, differential adipogenic ac- tivity of multiple PPAR isoforms (Bran et al.), 974-984
AINTEGUMENTA, similarity of maize Gtossyt5 tMoose and Siscol, 3018-3027
Alport syndrome, COL4A3-deficient mice as model (Cosgrove et al.), 2981- 2992
AML1, homologous domains found in Drosophila Lozenge (Daga et al.), 1194-1205
Anaphase, regulation in S. cerevisiae by APC-dependent degradation of Pdslp (Cohen-Fix et al.), 3081- 3093
Anaphase-promoting complex, role in Pdslp degradation in (Cohen- Fix et al.), 3081-3093
Anchoring site, binding by U2 snRNP proteins (Gozani et al.), 233-243
Anti-cancer agents, p53-dependent cell cycle arrest induced by ribonu- cleotide depletion (Linke et al.), 934-947
Anticodon, as signal sequence for tRNA import into mitochondria (Rusconi and Cech), 2870-2880
Antimetabolites, induction of p53-de- pendent cell-cycle arrest by ri- bonucleotide depletion [Linke et al.), 934-947
Antisigma factor, interaction of SpoIIAB with ~r in B. subtilis (Decatur and Losick), 2348-2358
APC. See Anaphase-promoting complex APETALA2, similarity of maize Glossyl 5
(Moose and Sisco), 3018-3027 APETALA3, nuclear colocalization with
PISTILLATA (McGonigle et al.), 1812-1821
Apoptosis. See also Programmed cell death
Bcl-xL and p53 in mitotic checkpoint control (Minn et al.), 2621-2631
BID as novel death agonist possessing only a BH3 domain (Wang et al.), 2859-2869
effects of wild-type p53 transgene ex-
pression (Godley et al.), 836- 850
functional interaction of E1B 19K with Bax (Han et al.), 461-477
genetic determinants of p53 induction (Polyak et al.), 1945-1952; Erra- tum, 2818
induction by ectopic E2F expression in Drosophila (Asano et al.1, 1422- 1432
negative regulation of MAP4 expres- sion by p53 (Murphy et al.), 2971-2980
opposing cell-death activities in C. el- egans neurons (Shaham and Horvitz), 578-591
p53 levels and extent of tumor cell re- sponse (Chen et al.), 2438-2451
in plO7-null mice (Lee et al.), 1621- 1632
in R b ' / mice (Nikitin and Lee), 1870-1879
regulation of skeletal muscle cell pro- liferation by Rb (Zackenhaus et al.), 3051-3064
regulators and pathways (White), 1-15 Review
rise and fall during multistage tumor- igenesis (Naik et al.), 2105-2116
role of grim in Drosophila (Chen et al.),
1773-1782 p53 (Ko and Prives), 1054-1072 Re-
view TrkB and TrkC in promoting neuron
survival (Minichello and Klein), 2849-2858
XPB and XPD in p53-dependent pathway (Wang et al.), 1219- 1232
substrate specificities of CED-3/ICE- like proteases (Xue et al.), 1073- 1083
suppression by E26 v-Myb (Frampton et al.), 2720-2731
tissue-specific inactivation of p53 tu- mor suppression in mice (Bow- man et al.), 826-835
up-regulation by dominant interfering Myb (Taylor et al.), 2732-2744
Appressorium, formation during rice blast fungus M. grisea infection (Xu and Hamer), 2696-2706
Arabidopsis, nuclear colocalization of APETALA3 and PISTILLATA (McGonigle et al.), 1812-1821
araucan, positive regulation of by Dpp and Ci during wing patterning (G6mez-Skarmeta and Mod- olell), 2935-2945
Arches, branchial, role of pescadillo de- velopment in zebrafish (Allende et al.), 3141-3155
ASF. See ASF/SF2
GENES & DEVELOPMENT 3227
ASF/SF2, role in activation of polyadenylation by in-
tron enhancer (Lou et al.), 208- 219
cell viability (Wang et al.), 2588-2599 in splicing (Manley and Tacke), 1569-
1579 Review Asymmetric cell division. See Cell divi-
sion, asymmetric Asymmetry, coupling of cell lineage
asymmetry with transcription of unc-86 (Baumeister et al.), 1395-1410
Ataxia telangiectasia. See ATM Atf-1, regulation by Spcl in S. pombe
(Shiozaki and Russell), 2276-- 2288
ATF2. See Activating transcription fac- tor-2
ATM association with meiotically pairing
chromosomes (Keegan et al.), 2423-2437
effects of gene inactivation in mice (Xu et al.), 2411-2422
role in cell-cycle regulation (Xu and Balti-
more), 2401-2410 different cell types and functional
links to p53 (Hawley and Friend), 2383-2388 Review
Atr, association with meiotically pairing chromosomes (Keegan et al.), 2423-2437
Attenuator, Fab-7 as boundary element in Drosophila
(Zhou et al.), 3195-3201 as chromatin domain boundary in
Drosophila (Hagstrom et al.), 3202-3215
Axial growth, role of Axl2p in bud-site selection in yeast (Roemer et al.), 777-793
Axis formation, role of ~-catenin and Xgsk-3 in Xenopus (Yost et al.), 1443-1454
AXL2, role in axial growth site selection in yeast (Roemer et al.), 777- 793
B
B cells Pax-5 recruitment of Ets proteins to
mb-I promoter (Fitzsimmons et al.), 2198-2211
proteins, sequence-specific DNA bind- ing of POU domain coactivator OCA-B (Cepek et al.), 2079- 2088
role of p3OO/CBP and bHLH proteins in differentiation (Eckner et al.), 2478-2490
Bacillus subtilis
bifunctionality of SpoIIE in asymmet- ric cell division and cell-specific transcription (Feucht et al.), 794-803
bipolar localization of FtsZ (Levin and Losick), 478-488
interaction of SpoIIAB with (r F (Deca- tur and Losick), 2348-2358
role of extracellular peptide in differ- ent development pathways (So- lomon et al.), 2014-2024
signaling by serine kinases and phos- phatases in response to stress (Yang et al.), 2265-2275
BAFs. See BRGl-associated factors bagpipe, role in segmentation and speci-
fication of Drosophila meso- derm (Azpiazu et al.), 3183- 3194
Bar, positive regulation by Drosophila Lozenge (Daga et al.), 1194- 1205
Base pairing, of U2 and U6 snRNAs dur- ing splicing (Field and Friesen), 489-501
Basement membrane, effects of collagen COL4A3 gene inactivation in mice (Cosgrove et al.), 2981- 2992
basket, as encoding Drosophila JNK (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.), 2759- 2768
Bax interaction with E1B 19K (Han et al.),
461-477 up-regulation by p53 (Ko and Prives),
1054-1072 Review Bcl-2 family
functional interaction of E1B 19K with Bax (Han et al.), 461-477
role in apoptosis (White), 1-15 Review cell-death activities in developing C.
elegans neurons (Shaham and Horvitz), 578-591
Bcl-x L BID as novel death agonist possessing
only a BH3 domain (Wang et al.), 2859-2869
regulation of apoptosis during multistage tumori-
genesis (Naik et al.), 2105-2116 bcl-2 by dominant interfering Myb
(Taylor et al.), 2732-2744 role in mitotic checkpoint control
(Minn et al.), 2621-2631 up-regulation of bcl-2 by E26 v-Myb
(Frampton et al.), 2720-2731 Belousov-Zhabotinsky reaction, propa-
gation of traveling waves (Sager), 2237-2250 Review
B-Catenin perturbation of distribution by forced
expression of E-cadherin (Her- miston et al.), 985-996
regulation by Xgsk-3 (Yost et al.), 1443-1454
role in signal transduction during em- bryogenesis (Miller and Moon), 2527-2539 Review
~-Globin, role of EKLF in human gene competition (Wijgerde et al.), 2894-2902
~-Globin 5'HS2 enhancer, in the study of position-effect variegation (Wai- ters et al.), 185-195
BH3 domain, in novel death agonist BID (Wang et al.), 2859-2869
bHLH proteins. See Helix-loop-helix pro- teins, basic
bicoid, novel related homeo box factor Ptxl (Lamonerie et al.}, 1284- 1295
BID, novel death agonist possessing only a BH3 domain {Wang et al.), 2859-2869
Bithorax complex, Fab-7 attenuation of enhancer-promoter in-
teractions in Drosophila (Zhou et al.), 3195-3201
chromatin domain boundary in Droso- phila (Hagstrom et al.), 3202- 3215
BMP-4, activation of Lefl expression (Kratochwil et al.), 1382-1394
Bmp4, regulation by zebrafish dino and swirl (Hammerschmidt et al.), 2452-2461
BMPs. See Bone morphogenetic proteins Bone morphogenetic proteins
regulation of Bmp4 by dino and swir/ in zebrafish (Hammerschmidt et al.), 2452-2461
role in embryonic development (Hogan), 1580-1594 Review
role of Bmp8b in spermatogenesis and fertility in mice (Zhao et al.), 1657-1669
Boundary elements, Fab-7 attenuation of enhancer-promoter in-
teractions in Drosophila (Zhou et al.), 3195-3201
chromatin domain boundary in Droso- phila (Hagstrom et al.), 3202- 3215
Branchial arches. See Arches, branchial Branchpoint sequences, binding up-
stream by U2 snRNP proteins and spliceosome assembly (Goz- ani et al.), 233-243
Brcal, effects of gene inactivation in mice (Liu et al.), 1835-1843
Breathless, role in patterning cell migra- tion and branching in Droso- phila (Lee et al.), 2912-2921
BRGl-associated factors, similarity to yeast SWI/SNF factors (Wang et al.), 2117-2130
BSAP, recruitment of Ets proteins to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211
3228 GENES & DEVELOPMENT
B u d site inhibition of ATF-2 activation by its
DNA-binding domain (Li and Green), 517-527
role of Axl2p in selection (Roemer et al.), 777-793
bZIP protein. See Leucine zipper protein, basic
C
C-factor. See C-signaling C-signaling
branched pathway in Myxococcus (Sogaard-Andersen et al.), 740- 754
traveling wave propagation in Myxo- coccus morphogenesis tSager}, 2237-2250 Review
c-Jun amino-terminal kinases activation by HPK1 (Hu et al.), 2251-
2264 Drosophila pathway mediating mor-
phogenesis and an immune re- sponse (Sluss et al.), 2745-2758
regulation of Atfl by Styl in S. pombe (Wilkinson et al.), 2289-2301
c-Myb, role of EVES motif in regulation (Dash et al.), 1858-1869
c-myc collaboration with NotchI for onco-
genesis (Girard et al.), 1930- 1944
specificity in gene activation by Myc (Desbarats et al.), 447-460
c-ros, role of in epithelial development (Sonnenberg-Riethmacher et al.), 1184-1193
c - s r c
effects of gene disruptions in mice (Lowell and Soriano), 1845- 1857 Review
regulation of eye development by re- lated Drosophila gene Dsrc41 (Takahashi et al.), 1645-1656
C/EBPs. See CCAAT/enhancer-binding proteins
Cadherins colocalization of Drosophila Dsrc41
and DE-cadherin in developing eyes (Takahashi et al.), 1645- 1656
role in intestinal epithelial cell migra- tion (Hermiston et al.), 985-996
Caenorhabditis elegans coupling of cell lineage asymmetry
with unc-86 transcription (Bau- meister et al.), 1395-1410
in vitro transposition of Tcl (Vos et al.), 755-761
opposing cell-death activities in devel- oping neurons (Shaham and Horvitz), 578-591
posterior patterning by vab-7 (Ahr- inger), 1120-1130
role of FEM-2 in sex determination (Chin-
Sang and Spence), 2314-2325 lin-14 3' UTR in down-regulation of
translation (Ha et al.), 3041- 3050
lin-17 in asymmetric cell division in (Sawa et al.), 2189-2197
sere-4 in neuronal and mesodermal development (Basson and Hor- vitz), 1953-1965
SL1 trans-spliced leader RNA in em- bryogenesis (Ferguson et al.), 1543-1556
substrate specificities of CED-3/ICE- like proteases (Xue et al.), 1073- 1083
Calcitonin alternative splicing of pre-mRNA (Lou
et al.), 208-219 gene-related peptide, generation
through alternative splicing of calcitonin pre-mRNA (Lou et al.), 208-219
cAMP. See Cyclic AMP Cancer. See also Carcinogenesis; Onco-
genesis; Specific oncogenes; Tu- morigenesis
ATM as susceptibility gene (Hawley and Friend), 2383-2388 Re- view
breast, effects of Brcal gene inactiva- tion in mice (Liu et al.), 1835- 1843
p53-dependent cell cycle arrest in- duced by ribonucleotide deple- tion (Linke et al.), 934-947
rearrangement of Notch l in mouse thymomas in MMTV/myc transgenic mice (Girard et al.), 1930-1944
redundancy of MSH3 and MSH6 in MSH2-dependent mismatch re- pair (Marsischky et al.), 407- 420
tissue-specific inactivation of p53 tu- mor suppression in mice (Bow- man et al.), 826-835
Cap-binding complex, nuclear Mudl3p as yeast homolog of CBP20
(Colot et al.), 1699-1708 role in pre-mRNA recognition and
splicing (Lewis et al.), 1683- 1698
Cap-binding protein, requirement for ri- bosome jumping in virus-in- fected and heat-shocked cells (Yueh and Schneider), 1557- 1567
Cap-prevented recombination. See Re- combination, cap-prevented
Carboxy-terminal domain, role in Pol II transcription (Orphanides et al.), 2657-2683 Review
Carcinogenesis, neuroendocrine role of Rb (Nikitin and Lee), 1870-1879
Caulobacter crescentus, role of Lon pro- tease in cell-cycle control of DNA methylation (Wright et al.), 1532-1542
caupolican, positive regulation of by Dpp and Ci during wing pat- terning (G6mez-Skarmeta and Modolell), 2935-2945
CBC. See Cap-binding complex, nuclear CBP. See CREB-binding protein CBP20, identification of yeast homolog
Mudl3p (Color et al.), 1699- 1708
CCAAT/enhancer-binding proteins, role of
C/EBP-~ in elevation of p21 (Tim- chenko et al.), 804-815
interaction with Rb in adipocyte ter- minal differentiation (Chen et al.), 2794-2804
CcrM, as target of Lon protease in Cau- lobacter (Wright et al.), 1532- 1542
CD40, role of TANK in CD40L-medi- ated NF-KB activation (Cheng and Baltimore), 963-973
Cdc2 kinase, inhibition by Ruml (Jalle- palli and Kelly), 541-552
Cdc2/cyclin B complexes, regulation by Xenopus Sucl homolog Xe-p9 (Patra and Dunphy), 1503-151
Cdc6, role in promoting replication during the cell
cylce (Piatti et al), 1516--1531 regulation of eukaryotic DNA replica-
tion (Diffley), 2819-2830 Review Cdc7, role in regulation of eukaryotic
DNA replication (Diffley), 2819-2830 Review
Cdcl0, AXL2 as high copy suppressor in spa2~ cdcl0-10 mutant strains (Roemer et al.), 777-793
Cdc 18, interaction with Rum 1 (Jallepalli and Kelly), 541-552
Cdc25, degradation of maternal mRNAs in maternal/zygotic transition (Edgar and Datar), 1966-1977
Cdc28p, role in regulation of eukaryotic DNA replication (Diffley), 2819-2830 Review
CDC37, encoding of protein kinase-tar- geting subunit of Hsp90 by mammalian homolog (Stepa- nova et al.), 1491-1502
CDC55, as encoding the regulatory sub- unit of ceramide-activated pro- tein phosphatase in S. cerevi- siae (Nickels and Broach), 382- 394
CDK inhibitors. See Cyclin-dependent kinase inhibitors
cdk2 regulation of cyclin E turnover by the
ubiquitin pathway (Clurman et al.), 1979-1990
role in control of pRB and E2F function
GENES & DEVELOPMENT 3229
during G 1 exit (Hofmann and Livingston), 851-861
cdk3, dominant-negative inhibition of E2F-1 in Rb-independent man- ner (Hofmann and Livingston), 851-861
cdk5, regulation of neurite outgrowth (Nikolic et al.), 816-825
CDKs. See Cyclin-dependent kinases CED-3, substrate specificities of ICE-like
proteases (Xue et al.), 1073-1083 ced-3, role in cell-death activities in de-
veloping C. elegans neurons (Shaham and Horvitz), 578-591
ced-4, role in cell-death activities in de- veloping C. elegans neurons (Shaham and Horvitz), 578-591
ced-9, role in cell-death activities in de- veloping C. elegans neurons (Shaham and Horvitz), 578-591
Cell adhesion, role of cadherins in intesti-
nal epithelium (Hermiston et al.), 985-996
cycle arrest from p21 overexpression in
transgenic mice (Wu et al.), 245-260
arrest induced by ribonucleotide de- pletion (Linke et al.), 934-947
Bcl-x L and p53 in mitotic check- point control {Minn et al.), 2621-2631
cdk-dependent cyclin E ubiquitina- tion (Clurman et al.), 1979- 1990
cdk2 and cdk3 action in G 1 (Hof- mann and Livingston), 851-861
ceramide-activated protein phos- phatase mediates ceramide-in- duced G 1 arrest in Saccharomy- ces cerevisiae (Nickels and Broach), 382-394
coincident regulation with clonality during T-cell receptor develop- ment (Hoffman et al.), 948-962
cyclin E requirement for E2F-in- duced S phase (Duronio et al.), 2505-2513
determinants of late origin activa- tion in yeast (Friedman et al.), 1595-1607
induction of S phase by ectopic E2F expression in Drosophila {Asano et al.), 1422-1432
influence of p53 levels on arrest (Chen et al.), 2438-2451
modulators of histone function in yeast (Ma et al.), 1327-1340
p53-dependent arrest induced by ri- bonucleotide depletion (Linke et al.), 934-947
parallel sensory branches for DNA damage signaling in S. cerevi- siae (Navas et al.), 2632-2643
protection of E2F-1 from ubiquitin-
proteasome degradation path- way by Rb {Hofmann et al.), 2949-2959
regulation by ATM (Xu and Baltimore),
2401-2410 of E2F degradation by Rb family
proteins and adenovirus trans- forming proteins (Hateboer et al.), 2960-2970
of S-phase onset by fission yeast ORC1 homolog orpl (Grallert and Nurse), 2644-2654
of SBF binding (Koch et al.), 129- 141
of skeletal muscle cell prolifera- tion by Rb (Zackenhaus et al.), 3051-3064
by Xenopus Sucl homolog Xe-p9 {Patra and Dunphy), 1503-151
requirement for yeast TAFn90 (Apone et al.), 2368-2380
role of Lon protease in control of DNA
methylation (Wright et al.), 1532-1542
p21 in keratinocyte growth and differentiation {Missero et al.), 3065-3075
p53 (Ko and Prives), 1054-1072 Review
rapamycin-sensitive TOR func- tion in yeast (Alarcon et al.), 279-288
Rb interaction with C/EBPs in ad- ipocyte terminal differentiation (Chen et al.), 2794-2804
Rum 1 inhibition of Cdc2 kinase and interaction with Cdcl8 {Jalle- palli and Kelly), 541-552
termination of early program in Drosophila embryogenesis (Ed- gar and Datar), 1966-1977
timing of replication promotion by Cdc6 {Piatti et al.), 1516-1531
truncation of S phase during the Drosophila endocycle (Lilly and Spradling), 2514-2526
division asymmetric
coupling of cell lineage asymme- try with unc-86 transcription (Baumeister et al.), 1395-1410
role of lin-I 7 in C. elegans (Sawa et al.), 2189-2197
role of SpoIIE in Bacillus subtilis (Feucht et al.), 794-803
bipolar localization of FtsZ in Bacil- lus subtilis (Levin and Losick), 478-488
fate cadherins role in intestinal epitheli-
al cell migration (Hermiston et al.), 985-996
signal transduction role through ~-catenin during embryogenesis
(Miller and Moon), 2527-2539 Review
growth defects in ATM-deficient mice (Xu
et al.), 2411-2422 interactions, regulation by Dsrc41
in developing Drosophila eyes (Takahashi et al.), 1645-1656
invasion, regulation of tumor cell plasticity by TGF-[3 and Ha-Ras (Oft et al.), 2462-2477
regulation by ATM (Xu and Balti- more), 2401-2410
migration Breathless role in the Drosophila
tracheal system (Lee et al.), 2912-2921
C-signaling role and traveling wave propagation in Myxococcus (Sager), 2237-2250 Review
cadherins role in intestinal epithe- lium (Hermiston et al.), 985-996
cAMP role and traveling wave prop- agation in Dictyostelium (Sager), 2237-2250 Review
Heartless role in Drosophila devel- opment (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017
polarity, regulation by lin-I 7 in C. el- egans (Sawa et al.), 2189-2197
rearrangement, epithelial E-cadherin role in Drosophila (Ue-
mura et al.), 659-671; (Tepass et al.), 672-685
signaling during Drosophila oogenesis (Ray
and Schfipbach), 1711-1723 Re- view
in hepatic specification of gut endo- derm (Gualdi et al.), 1670-1682
role of extracellular peptide in differ- ent development pathways in B. subtilis (Solomon et al.), 2014- 2024
specificity conversion of ~NAC to myotube-
specific factor (Yotov and St-Ar- naud), 1763-1772
Pax-5 recruitment of Ets proteins to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211
role of novel bicoid-related homeo box factor Ptxl (Lamonerie et al.), 1284-1295
sequence-specific DNA binding of B-cell POU domain coactivator OCA-B {Cepek et al.), 2079- 2088
tissue-specific inactivation of p53 tu- mor suppression in mice (Bow- man et al.), 826--835
Central nervous system. See Nervous system, central
Ceramide-activated protein phos-
3230 GENES & DEVELOPMENT
phatase. See Protein phos- phatase, ceramide-activated
Cerebellum, role of TrkB and TrkC in promoting granule neuron sur- vival (Minichello and Klein), 2849-2858
CF. See Core factor CF2, role in EGF-R-activated dorsoven-
tral patterning (Hsu et al.), 1411-1421
Chaperone proteins, p50 Cdc37 as protein kinase-targeting subunit of Hsp90 (Stepanova et al.), 1491- 1502
Checkpoints activation by V(D)] recombination in
scid mice (Guidos et al.), 2038- 2054
Bcl-x L and p53 in control (Minn et al.), 2621-2631
cooperativity of p53 and SCID genes in tumorigenesis (Nacht et al.), 2055-2066
cyclin E role in truncation of S phase during the Drosophila endocy- cle (Lilly and Spradling), 2514- 2526
parallel sensory branches for DNA damage signaling in S. cerevi- siae (Navas et al.), 2632-2643
regulation of S-phase onset by fission yeast ORC1 homolog orpl (Grallert and Nurse), 2644-2654
Spk1/Rad53 regulation by Mecl-de- pendent protein phosphoryla- tion (Sun et al.), 395-406
topoisomerases role in chromosome condensation in S. cerevisiae (Castaflo et al.), 2564-2576
• preferred selection by RecA protein (Tracy and Kowalczykowski), 1890-1903
Cholesterol metabolism, mediation of SREBP transcriptional activity by CBP (Oliner et al.), 2903- 2911
Chromatin activator-dependent regulation of tran-
scriptional pausing on nucleo- somal templates (Brown et al.), 1479-1490
findings presented at Cold Spring Har- bor meeting (McKnight), 367- 381 Meeting commentary
function of Swp73 in yeast Swi/Snf complex (Cairns et al.), 2131- 2144
identification of mammalian SWI/ SNF complexes (Wang et al.), 2117-2130
in transcriptional activation and re- pression (Kingston et al.), 905- 920 Review
interaction of Tupl with histones H3 and H4 (Edmondson et al.), 1247-1259
NF-KB p50 role in nucleosome arrange- ment of HIV-1 enhancer (Pazin et al.), 37-49
role in hepatic specification of gut en- doderm (Gualdi et al.), 1670- 1682
silent, preferential integration of Ty5 (Zou et al.), 634-645
Chromosome association of Atr and Atm with mei-
otic pairs (Keegan et al.), 2423- 2437
condensation, role of topoisomerases in S. cerevisiae (Castafio et al.), 2564-2576
fragmentation in ATM-def icient mice (Xu et al.), 2411-2422
localization of TFIID and inhibition of activator-dependent transcrip- tion (Segil et al.), 2389-2400
organization dif resolvase site insertions in E. coli
(Kuempcl et al.), 1162-1171; Corrigendum, 1709
restriction of dif site activity in E. coli (Cornet et al.), 1152-1161
walk, to identify determinants con- trolling activation of yeast rep- lication origins (Friedman et al.), 1595-1607
ci. See cubitus interruptus CIF, role in TFIID-dependent initiator
function (Kaufmann et al.), 873- 886
CIP- 1. See p21 CKIs. See Cyclin-dependent kinase in-
hibitors Clb5. See Cyclins Clb6. See Cyclins Cleavage-polyadenylation specificity
factor, interaction with U1 snRNP (Lutz et al.), 325-337
Clnl. See Cyclins Cln2. See Cyclins Cln3. See Cyclins CNS. See Nervous system, central Coactivators, transcriptional
findings presented at Cold Spring Har- bor meeting (McKnight), 367- 381 Meeting commentary
interaction of CBP with (Dai et al.), 528-540
mediation of SREBP transcriptional activity by CBP (Oliner et al.), 2903-2911
role of TFIIA in Ras-mediated photore- ceptor determination (Zeidler et al.), 50-59
sequence-specific DNA binding of B-cell POU domain coactiva- tor OCA-B (Cepek et al.), 2079- 2088
Coconversion, biases accompanying in- tron homing (Mueller et al.), 2158-2166
Cofactors
role of EVES motif in c-Myb regulation (Dash et al.), 1858-1869
transcriptional findings presented at Cold Spring
Harbor meeting (McKnight), 367-381 Meeting commentary
role of CIF in TFIID-dependent ini- tiator function (Kaufmann et al.), 873-886
COL4A3, effects of gene inactivation in mice (Cosgrove et al.), 2981-2992
Collagen, effects of COL4A3 gene inac- tivation in mice (Cosgrove et al.), 2981-2992
Competence and sporulation stimulat- ing factor, role of extracellular peptide in different develop- ment pathways in B. subtil is (Solomon et al.), 2014-2024
Competence, genetic, role of extracellu- lar peptide in B. subtiIis (So- lomon et al.), 2014-2024
Conjugation Atfl regulation by
Spcl in S. pombe (Shiozaki and Rus- sell), 2276--2288
Styl in S. p o m b e (Wilkinson et al.), 2289-2301
conjugating plasmids as preferred tar- gets for Tn7 (Wolkow et al.), 2145-2157
Copper transport, role of yeast protein Ctr3 (Knight et al.), 1917-1929
Core factor, requirement for TBP in UAF-dependent recruitment (Steffan et al.), 2551-2563
Corepressors, role of KAP-1 for KRAB domain (Friedman et al.), 2067- 2078
Corkscrew, analysis of interaction with Torso (Cleghon et al.), 566--577
Corrigenda Gertler et al., 2234 Kuempel et al., 1709
CPP32, similarity CED-3 substrate spec- ificity (Xue et al.), 1073-1083
CPR. See Recombination, cap-prevented CPSF. See Cleavage-polyadenylation
specificity factor CREB-binding protein
as a coactivator of c-Myb (Dai et al.), 528-540
role in cell differentiation (Eckner et al.),
2478-2490 mediation of SREBP transcriptional
activity (Oliner et al.), 2903- 2911
Crk, phosphorylation of Sin (Alexandro- poulos and Baltimore), 1341- 1355
Crypt-villus, role of cadherins in intesti- nal epithelial cell migration (Hermiston et al.), 985-996
CSF. See Competence and sporulation stimulating factor
GENES & DEVELOPMENT 3231
csgA branched C-factor signaling pathway
in Myzococcus (Sogaard-Ander- sen et al.), 740-754
C-signaling and traveling wave propaga- tion in Myzococcus {Sager), 2237-2250 Review
CTD. See RNA polymerase, carboxy-ter- minal domain
CTR3, role of protein product in copper transport in yeast (Knight et al.), 1917-1929
cubitus interruptus activation of patched in response
Hedgehog signaling (Alexandre et al.), 2003-2013
positive regulation of araucan and caupolican (G6mez-Skarmeta and Modolell), 2935-2945
CUS1, role of gene product in spliceo- some assembly (Wells et al.), 220-232
Cyclic AMP regulation of rice blast fungus M.
grisea infection (Xu and Hamer), 2696-2706
traveling wave propagation in Dictyo- stelium (Sager), 2237-2250 Re- view
Cyclin-dependent kinase inhibitors effect of p21 overexpression in trans-
genie mice (Wu et al.), 245-260 role of p21 in keratinocyte growth and
differentiation (Missero et al.), 3065-3075
Ruml inhibition of Cdc2 kinase and interaction with Cdc18 (Jalle- palli and Kelly), 541-552
vitamin D 3 induction of p21 (Liu et al.), 142-153
Cyclin-dependent kinases activation by Cdc6 during the cell
cylce (Piatti et al.), 1516-1531 cdk2 and cdk3 action in G1 (Hofmann
and Livingston), 851-861 Cdk4 as target of Cdc37 in mouse fi-
broblasts (Stepanova et al.), 1491-1502
cell-cycle regulation of SBF binding (Koch et al.), 129-141
regulation of neurite outgrowth by cdk5/p35 kinase (Nikolic et al.), 816-825
role of Xenopus Sucl homolog Xe-p9 in cell cycle control (Patra and Dunphy), 1503-1515
Cyclins cdk-dependent cyclin E ubiquitination
(Clurman et al.), 1979-1990 cell-cycle regulation through SBF
(Koch et al.), 129-141 Clb/Cdc28 in displacing SBF from pro-
moters during G2 (Koch et al.), 129-141
cyclin E requirement for E2F-induced
S phase (Duronio et al.), 2505- 2513
effect of p21 overexpression on cyclin- CDK complex activity (Wu et al.), 245-260
p53-dependent induction of cyclin G (Ko and Prives), 1054-1072 Re- view
role of cyclin E in S phase during the Drosophila endocycle (Lilly and Spradling), 2514-2526
Cyclins, D-type, coexpression of Cdc37 with cyclin D1 in proliferating cells (Stepanova et al.), 1491- 1502
Cysteine proteases role in
apoptosis (White), 1-15 Review cell-death activities in developing C.
elegans neurons (Shaham and Horvitz), 578-591
substrate specificities of CED-3/ICE- like proteases (Xue et al.), 1073- 1083
Cytokinesis, role of drnfl/midl in posi- tioning of division septum in fission yeast (Sohrmann et al.), 2707-2719
Cytoskeleton, role of plectin in mem- brane adherence (McLean et al.), 1724-1735
Danio rerio prospects for insertional mutagenesis
(Schier et al.), 3077-3080 Mini- review
role of pescadillo and dead eye in em- bryonic development (Allende et al.), 3141-3155
dead eye, role in zebrafish development (Allende et al.), 3141-3155
Decapentaplegic positive regulation of araucan and
caupolican (G6mez-Skarmeta and Modolell), 2935-2945
prevention of autoactivation by sog (Biehs et al.), 2922-2934
decapentaplegic, activation by Cubitus interruptus (Alexandre et al.), 2003-2013
Delta, in Drosophila wing development (Doherty et al.), 421-434
Dentate gyrus, role of TrkB and TrkC in promoting neuron survival (Minichello and Klein), 2849- 2858
Development, general cloning of a novel human kinase gene
with homology to Drosophila female sterile homeotic (Denis and Green), 261-271
effects of in vivo mutagenesis of re-
quired HoxD complex regula- tory element (Gdrard et al.), 2326-2334
mechanism of hepatic specification of gut endoderm (Gualdi et al.), 1670-1682
Rasl-mediated signaling by PP2A (Wassarman et al.), 272-278
role of Heartless in Drosophila cell migra-
tion and mesodermal lineage development (Beiman et al.), 2993-3002; (Gisselbrecht et al.), 3003-3017
lin-14 3' UTR temporal gradient for- mation in C. elegans (Ha et al.), 3041-3050
pescadillo and dead eye in zebrafish embryogenesis (Allende et al.), 3141-3155
p53 (Ko and Prives), 1054--1072 Re- view
Development, specific. See also Specific organisms
axial, mouse Wnt-3a gene dosage reg- ulation (Greco et al.), 313-324
bone, role of Src-family kinases (Low- ell and Soriano), 1845-1857 Re- view
cartilage, role of p107 and p130 in mice (Cobrinik et al.), 1633- 1644
embryonic requirement for Hlx during mouse
visceral organogenesis (Hentsch et al.), 70-79
role of BMPs (Hogan), 1580-1594 Review
epithelial, role of c-ros (Sonnenberg- Riethmacher et al.), 1184--1193
eye effects on photoreceptor specifica-
tion through regulation of Lozenge role in Drosophila (Daga et
al.), 1194-1205 mouse Pax6 role (Quinn et al.), 435-
446 Rasl regulation of prospero tran-
scription in Drosophila (Kauff- mann et al.), 2167-2178
regulation by Dsrc41 in Drosophila (Takahashi et al.), 1645-1656
TFIIA role in Ras-mediated photore- ceptor determination (Zeidler et al.), 50-59
hair, regulation of inductive tissue in- teractions by Lefl expression (Kratochwil et al.), 1382-1394
immune system, coincident regula- tion of cell cycle and clonality during T-cell receptor develop- ment (Hoffman et al.), 948-962
kidney abnormalities in wild-type p53
transgenic mice (Godley et al.), 836-850
3232 GENES & DEVELOPMENT
regulation by Winged Helix protein BF-2 (Hatini et al.), 1467-1478
role of BMPs (Hogan), 1580-1594 Review
leaf, role of Glossyl5 in maize (Moose and Sisco), 3018-3027
liver, effect of p21 overexpression in transgenic mice (Wu et al.), 245-260
lymphoid, role of Src-family kinases (Lowell and Soriano), 1845- 1857 Review
male, role of FEM-2 phosphatase in C. elegans (Chin-Sang and Spence), 2314-2325
mesodermal, role of C. elegans sere-4 (Basson and Horvitz), 1953- 1965
nasal, role of mouse Pax6 (Quinn et al.), 435-446
neural opposing cell-death activities in C.
elegans neurons (Shaham and Horvitz), 578-591
regulation of neurite outgrowth by cdk5/p35 kinase (Nikolic et al.), 816-825
role of BMPs (Hogan), 1580-1594 Review Src-family kinases (Lowell and So-
riano), 1845-1857 Review neuronal
role of C. elegans sere-4 (Basson and Horvitz), 1953-1965
role of TrkB and TrkC in promot- ing neuron survival (Minichello and Klein), 2849-2858
postimplantation, abnormalities in Brcal-null mice (Liu et al.), 1835-1843
prokaryotic, branched signaling path- way in Myxococcus (Sogaard- Andersen et al.), 740-754
skeletal, role of BMPs (Hogan), 1580- 1594 Review
T-cell, cooperativity of p53 and SCID in lymphomagenesis (Nacht et al.), 2055-2066
tail bud, role of mouse Wnt-3a (Greco et al.), 313-324
tooth regulation of inductive tissue inter-
actions by Lefl expression (Kra- tochwil et al.), 1382-1394
role of BMPs (Hogan), 1580-1594 Review
tracheal, role of Breathless in pattern- ing cell migration and branch- ing in Drosophila (Lee et al.), 2912-2921
vertebrate, induction of patched by hedgehog in mice (Goodrich et al.), 301-,312
wing regulation of araucan and caupoli-
can during Drosophila pattern
formation {G6mez-Skarmeta and Modolell), 2935-2945
role of Delta in Drosophila (Doherty et al.), 421-434
Dictyostelium discoideum role of cAMP and traveling wave prop-
agation in morphogenesis (Sager), 2237-2250 Review
signal transduction regulation by ERK2 (Gaskins et al.), 118-128
dif, in Xer site-specific recombination (Blakely and Sherratt), 762-773
dif site restriction of activity in E. coli (Cornet
et al.), 1152-1161 resolvase site insertions in E. coli
(Kuempel et al.), 1162-1171; Corrigendum, 1709
Differentiation adipocyte
role of ADD1/SREBP1 (Kim and Spiegelman), 1096-1107
role of Rb interaction with C/EBPs (Chen et al.), 2794-2804
B-cell, role of p300/CBP and bHLH proteins (Eckner et al.), 2478- 2490
cellular, effects of wild-type p53 trans- gene expression {Godley et al.), 836-850
central nervous system, role of single factors in stem cell differentia- tion (Johe et al.), 3129-3140
differential adipogenic activity of mul- tiple PPAR isoforms (Brun et al.), 974-984
effects of erythropoietin receptor gene inactivation on primitive and definitive erythropoiesis (Lin et al.), 154-164
epithelial regulation by nude locus product
Whn (Brissette" et al.), 2212- 2221
role of c-ros (Sonnenberg-Riethma- cher et al.), 1184-1193
keratinocyte, role of Src-farnily ki- nases (Lowell and Soriano), 1845-1857 Review
muscle, role of p3OO/CBP and bHLH proteins (Eckner et al.), 2478- 2490
of myelomonocytes induced by vita- min D 3 (Liu et al.), 142-153
myoblast, role of NAC proteins (Yotov and St-Arnaud), 1763-1772
neuronal regulation of neurite outgrowth by
cdk5/p35 kinase (Nikolic et al.), 816-.825
role of Lozenge in Drosophila (Daga et al.), 1194-1205
prokaryotic, branched signaling path- way in Myxococcus (Sogaard- Andersen et al.), 740-754
role of cadherins in intestinal epithe-
lium {Hermiston et al.), 985- 996
role of p53 (Ko and Prives), 1054-1072 Review
sexual, role of MIS in mammalians (Mishina et al.), 2577-2587
skeletal muscle, regulation by Rb (Zackenhaus et al.), 3051- 3064
thymocytes, p53 rescue of V(D)J rear- rangement in scid mice (Bogue et al.), 553-565
DIG1 and DIG2, novel MAP kinase tar- gets in S. cerevisiae (Cook et al.), 2831-2848
dino, role in zebrafish development IHammerschmidt et al.), 2452- 2461
dmfl/midl , role in positioning of divi- sion septum in fission yeast (Sohr- mann et al.), 2707-2719
DNA bending, role in transcriptional stimu-
lation by NHP6A/B (Paull et al.), 2769-2781
binding cooperativity of the Oct-1 POU sub-
domains (Klemm and Pabo), 27- 36
sequence specificity of B-cell coacti- vator OCA-B (Cepek et al.), 2079-2088
-binding domains activation of patched by Cubitus in-
terruptus in response Hedgehog signaling (Alexandre et al.), 2003-2013
altered intracellular receptor activa- tion (Starr et al.), 1271-1283
inhibition of ATF-2 transcriptional activation (Li and Green), 517- 527
breaks, double-stranded, activation of DNA damage checkpoint by V(D)] recombination (Guidos et al.), 2038-2054
damage in ATM-deficient mice (Xu et al.),
2411-2422 p53 levels and extent of tumor cell
apoptotic response (Chen et al.), 2438-2451
parallel sensory branches for signal- ing in S. cerevisiae tNavas et al.), 2632-2643
role of p53 in radiation-induced dif- ferentiation in scid mice (Bogue et al.), 553-565
and Spkl/Rad53 regulation by Mecl-dependent protein phos- phorylation (Sun et al.), 395-406
helicases, role of XPB and XPD in p53- dependent apoptosis (Wang et al.), 1219-1232
methylation, role
GENES & D E V E L O P M E N T 3233
in activation of Xist (Panning and Jaenisch), 1991-2002
in establishing genomic imprinting (Tucker et al.), 1008-1020
of Lon protease in Caulobacter (Wright et al.), 1532-1542
methyltransferase, activity during oo- genesis and spermatogenesis (Tucker et al.), 1008-1020
polymerase ~, parallel sensory branches for signaling in S. cer- evisiae (Navas et al.), 2632- 2643
protein kinase activation of DNA damage check-
point by V(D)! recombination in scid mice (Guidos et al.), 2038- 2054
cooperativity of p53 and SCID genes in tumorigenesis (Nacht et al.), 2055-2066
repair bypass of scid defect by induction of
p53 DNA damage response pathways (Bogne et al.), 553- 565
effects of ATM gene inactiva- tion (Xu and Baltimore), 2401- 2410
encoding of Ku p70 homolog IRBP by Drosophila mus309 (Beall and Rio), 921-933
p53 role (Ko and Prives), 1054-1072 Review
XPB and XPD roles in p53-depen- dent apoptosis (Wang et al.), 1219-1232
replication parallel sensory branches for DNA
damage signaling in S. cerevi- siae (Navas et al.), 2632-2643
promotion by Cdc6 during the cell cycle (Piatti et al.), 1516-1531
regions of yeast RPA subunits with similarity to E. coli SSB pro- tomer (Philipova et al.), 2222- 2233
regulation and specification of eu- karyotic origins (Diffley), 2819- 2830 Review
Spk 1 / Rad53 regulation by Mec 1-de- pendent protein phosphoryla- tion (Sun et al.), 395-406
ribosomal, role of TBP in expression in S. cerevisiae (Steffan et al.), 2551-2563
topoisomerases, role in mitotic chro- mosome condensation in S. cer- evisiae (Castafio et al.), 2564- 2576
DNA-PK. See DNA protein kinase Domains, chromosomal, determinants
of late origin activation in yeast (Friedman et al.), 1595-1607
Dominant-negative mutants cdk2 and cdk3 cell cycle function
(Hofmann and Livingston), 851- 861
regulation of neurite outgrowth by cdk5/p35 kinase (Nikolic et al.), 816--825
role of ADD1/SREBP1 in adipocyte differentiation (Kim and Spiegelman), 1096-1107
Dorsal, activation by Toll, tube, and pelle (Norris and Manley), 862-872
Dorsal closure, mediation by Drosophila JNK pathway (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.), 2759-2768
Dorsal-ventral axis, prevention of Dpp autoactivation by Drosophila sog (Biehs et al.), 2922-2934
Double-strand break repair, role in in- tron mobility (Mueller et al.), 351-364
doublesex, assembly of specific SR pro- tein complexes at the splicing enhancer (Lynch and Maniatis), 2089-2101
Drl, corepressor requirement (Mermel- stein et al.), 1033-1048
Drl-associated polypeptide 1, require- ment for Drl-mediated repres- sion (Mermelstein et al.), 1033- 1048
DRAP1. See Drl-associated polypeptide 1
Drosophila activation of dorsal by Toll, tube, and
pelle (Norris and Manley), 862- 872
assembly of specific SR protein com- plexes at the doublesex splicing enhancer (Lynch and Maniatis), 2089-2101
binding of TFIID to downstream basal promoter element (Burke and Kadonaga), 711-724
cloning of a novel human kinase gene with homology to female sterile homeotic (Denis and Green), 261-271
compensatory signaling sites on Torso (Cleghon et al.), 566-577
cyclin E requirement for E2F-induced S phase (Duronio et al.), 2505- 2513
degradation of maternal mRNAs in maternal/zygotic transition (Edgar and Datar), 1966-1977
E-cadherin in epithelial cell rearrange- ment (Uemura et al.), 659-671; (Tepass et al.), 672-685
encoding of bHLH-PAS protein by trachealess
(Wilk et al.), 93-102 Ku p70 homolog IRBP by DNA re-
pair mutant mus309 (Beall and Rio), 921-933
Fab-7 attenuation of enhancer-pro- moter interactions in (Zhou et
al.), 3195-3201 gradual activation of transcription dur-
ing embryogenesis (Pritchard and Schubiger), 1131-1142
independent regulation of neighboring genes (Merli et al.), 1260--1270
induction of S phase and apoptosis by ectopic E2F expression in Drosophila (Asano et al.), 1422- 1432
intercellular signaling and polariza- tion of body axes during oogen- esis (Ray and Sch6pbach), 1711- 1723 Review
JNK pathway mediating morphogene- sis and an immune response (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.), 2759- 2768
posterior patterning by vab-7 (Ahr- inger), 1120-1130
prevention of Dpp autoactivation and suppression of neurogenesis by sog (Biehs et al.), 2922-2934
Rasl regulation of prospero transcrip- tion during eye development (Kauffmann et al.), 2167-2178
RB-related gene RBF (Duet al.), 1206-- 1218
regulation of eye development by Dsrc41 (Taka-
hashi et al.), 1645-1656 Rasl-mediated signaling by PP2A
(Wassarman et al.), 272-278 rescue of labial null by chicken or-
tholog Hoxb-1 (Lutz et al.), 176- 184
role of Breathless in patterning cell migra-
tion and branching in the tra- cheal system (Lee et al.), 2912- 2921
CF2 in EGF-R-activated dorsoven- tral patterning (Hsu et al.), 1411-1421
grim in cell death (Chen et al.), 1773-1782
Heartless in cell migration and me- sodermal lineage development (Beiman et al.), 2993-3002; (Gisselbrecht et al.), 3003-3017
Lozenge in eye development (Daga et al.), 1194-1205
plx in tracheal function (Zhang et al.), 1108-1119
porcupine in Wingless processing (Kadowaki et al.), 3116-3128
short-range repressors in regulation of complex loci (Gray and Levine), 700-710
TFIIA during RAS-mediated photo- receptor determination (Zeidler et al.), 50-59
trachealess in embryonic tube for- mation (Isaac and Andrew), 103-117
3234 GENES & DEVELOPMENT
Reviewers, Volume 10" (1996) The editors would like to thank the Editorial Board and the following scientists who were kind enough to review papers and provide advice during 1996.
*From October 18, 1995 to October 17, 1996
Adler, Paul Allshire, Robin Alt, Fred Alwine, James Ammerer, Gustave Anderson, David Anderson, Kathryn Anderson, Phillip Andrews, Brenda Ares, Manuel Arndt, Kim Artavanis-Tsakonas,
Spyridon Artzt, Karen Ashburner, Michael Austin, Stuart Ausubel, Frederick Avery, Leon Avner, Philip Baker, Tania Baldwin, Albert, Jr. Baltimore, David Bannerjee, Utpal Banuett, Flora Barbacid, Mariano Bardwell, James Bargmann, Cori Barlow, Denise Barres, Barbara Bartolomei, Marisa Barton, Mary K. Basler, Konrad Bate, Michael Beach, David Beato, Miguel Becker, Peter Beddington, Rosa Beggs, Jean Behringer, Richard Bell, Steve Benezra, Robert Benson, Spencer Berget, Susan Berk, Arnold Bernards, Rene Bernstein, Alan Berry, Marla Besmer, Peter Beug, Hartmut Bickmore, Wendy Bienz, Marianne Bier, Ethan Bingham, Paul Bird, Adrian
Bishop, Douglas Black, Douglas Blackwell, Keith Blobel, Gunter Blumenthal, Thomas Bock, August Bodmer, Rolf Boeke, Jeff Bohmann, Dirk Bolen, Joseph Botchan, Michael Bothwell, A1 Bouck, Noel Brady, Scott Brandriss, Marjorie Bravo, Rodrigo Brent, Rodger Brewin, Nick Brockdroff, Neil Buckingham, Margaret Buratowski, Stephen Burden, Steven Burgoyne, Paul Burley, Stephen Butler, Mark Cantley, Lewis Capecchi, Mario Carey, Michael Carlson, Marian Carr, Anthony Carroll, Sean Cashmore, Tony Cedar, Howard Chandler, Vicki Chant, John Chater, Keith Chen, Jasmine Cho, Ken Chorey, Joanne Clayton, David Cleary, Michael Coen, Donald Coffin, John Cole, Charles Collins, Kathy Cooley, Lynn Corces, Victor Corey, Suzanne Costantini, Frank Courey, Albert Crabtree, Gerald Craig, Elizabeth Craig, Nancy Cross, Frederick Damsky, Caroline Dangl, Jeff Darnell, James Darnell, Robert Davies, Kay de Lange, Titia Deng, Xiong-W DeRobertis, Eddy Desplan, Claude Dixit, Vishva
Donahue, Thomas Donehower, Lawrence Draetta, Giulio Dreyfuss, Gideon Driever, Wolfgang Drubin, David Duboule, Denis Dunn, Ashley Dunphy, William Dynlacht, Brian Dyson, Nicholas Dzierzak, Elaine Ebright, Richard Eisenman, Robert Elgin, Sally Elion, Elaine Emerson, Beverly Engel, Douglas Ephrussi, Anne Errington, Jeffrey Ewen, Mark Farmer, Stephen Fearon, Eric Felsenfeld, Gary Firtel, Richard Fishman, Mark Flavell, Richard Franke, Werner Frasch, Manfred Freedman, Len Freidberg, Errol Friend, Stephen Fuchs, Elaine Furuya, Masaki Gall, Joseph Galloway, Denise Geiduschek, Peter Gerace, Larry Gibbs, Clarence Gilman, Michael Glass, Christopher Glover, David Gober, James Goff, Stephen Gold, Lawrence Goldfarb, Mitchell Goldstein, Joseph Goodman, Richard Gordon, Colin Gorovsky, Martin Gottschling, Daniel Grabowski, Paula Gralla, Jay Graves, Barbara Green, Michael Greenblatt, Jack Greenwald, Iva Greider, Carol Gridley, Thomas Griep, Anne Groner, Bernard Grossman, Alan Grummt, Ingrid Grunstein, Michael
GENES & DEVELOPMENT 3219
Gruss, Peter Guthrie, Chris Haber, James Hahn, Steven Hake, Sarah Hall, Alan Hanahan, Doug Hannon, Gregory Hannun, Yosef Hargreaves, John Harper, Wade Harrison, Stephen Hartenstein, Volker Haselkorn, Robert Hauschka, Stephen Hawley, Scott Hayday, Adrian Hearing, Patrick Hengartner, Michael Henikoff, Steve Hernandez, Nouria Herskowitz, Ira Higgs, Doug Hill, Robert Hinnebusch, Alan Hinton, Barry Hirano, Tatsuya Hoch, James Hoeijmakers, Jan Hoffman, Michael Hogan, Brigid Holder, Nigel Holmgren, Robert Hope, Ian Howley, Peter Hoyt, Andrew Hughes, Steve Hunter, Tony Hurt, Edward Hurwitz, Jerard Hyman, Linda Hynes, Richard Ihle, James Ingraham, Holly Ish-Horowicz, David Jacks, Tyler Jackson, Ian Jackson, Stephen Jacobson, Alan Jackle, Herbert Jaenisch, Rudolph Jentsch, Stefan Jessen, Kristijian Johnson, Gary Johnson, Peter Johnson, Reid Johnston, Lee Johnston, Mark Jones, Katherine Joyner, Alexandra Jurgens, Gerd Kahmann, Regine Kalderon, Dan Kaplan, Jerry Karpen, Gary Kastan, Michael
Kaufman, Paul Keller, Walter Kenyon, Cynthia Kessin, Richard Kidwell-Brown, Margaret Kim, Stuart Kimelman, David Kimmel, Alan Kimmel, Charles Kingsley, David Kingston, Robert Kinmer, Christopher Klein, Hannah Kolodner, Richard Konderosi, Adam Konopka, James Koopman, Peter Korsmeyer, Stanley Kowalcykowski, Stephen Krainer, Adrian Krasnow, Mark Krumlauf, Robb Kustu, Sydney Lamond, Angus Landy, Art Lane, Daniel Lane, David Lassar, Andrew Lazenbnik, Yuri Leavitt, Andrew Leder, Phil Lee, David Lees, Jackie Lehmann, Alan Lehner, Christian Lemke, Greg Leptin, Maria Levin, David Levine, Arnold Levy, David Lewis, Susanna Lis, John Losick, Richard Lovell-Badge, Robin Lowe, Scott Lowry, Douglas Luhrmann, Reinhard Lustig, Art Lyon, Mary Maas, Richard MacDonald, Paul MacLeod, K. Maizels, Nancy Mak, Tak Malim, Michael Mangelsdorf, David Maniatis, Tom Mann, Jeffrey Marshall, Chris Martin, David Massague, Joan Mathews, Michael Mattaj, Iain Matthias, Patrick Meinke, David Melton, Doug
Mendenhall, Michael Miller, Lois Mirsky, Rhona Mitchell, Aaron Mizuuchi, Kiyoshi Mlodzik, Marek Model, Peter Modolell, Juan Mohun, Tim Moon, Randall Moore, Melissa Morimoto, Richard Moses, Harold Moses, Kevin Moss, Tom Murray, Andrew Murre, Cornelius Nabel, Gary Nasmyth, Kim Neuberger, Michael Neufeld, Elizabeth Nevins, Joseph Newlon, Carol Newman, Andrew Newport, John Nilsen, Timothy Niswander, Lee Nomura, Masayasu Nurse, Paul Nusse, Roel O'Farrell, Patrick Olson, Eric Oren, Moshe Orkin, Stuart Oft-Weaver, Terry Pabo, Carl Pace, Norman Parker, Malcolm Parker, Peter Parker, Roy Parkinson, Sandy Paro, Renato Parslow, Tristan Pavletich, Nikola Pendergast, Ann Marie Perlman, Philip Perlmann, Thomas Perrimon, Norbert Peterson, Craig Pfahl, Magnus Phillips, Simon Pillus, Lorraine Poellinger, Lorenz Polakis, Paul Posakony, James Priess, James Pringle, John Proudfoot, Nicholas Ptashne, Mark Pugh, B. Franklin Quail, Peter Rabbitts, Terry Raff, Martin Rajewsky, Klaus Ramakrishnan, Venki Reed, Robin
3220 GENES & DEVELOPMENT
Reed, Steve Reeder, Ronald Reik, Wolf Reinberg, Danny Reines, Daniel Reznikoff, William Rice, Andrew Rigby, Peter Rine, Jasper Rio, Donald Roberts, James Robertson, Elizabeth Roeder, Robert Rong, Li Roop, Dennis Rorschneider, Lawrence Rosbash, Michael Rose, Mark Rosenberg, Naomi Rosenfeld, M. Geoff Rossant, Janet Rushlow, Christine Russell, Marjorie Russell, Paul Ruvkun, Gary Rymond, Brian Sachs, Alan Sandmeyer, Suzanne Sanes, Josh Sarnow, Peter Schechter, Alan Schedl, Andreas Schedl, Paul Schedl, Timothy Schlessinger, Joseph Schfipbach, Trudi Schwab, Martin Schwarz-Sommer,
Zsuzsanna Scott, Matthew Semenza, Gregg Shackleford, Gregory Shilo, Ben-Zion Shimkets, Lawrence Shimura, Yoshiro Shore, David Siebenlist, Ulrich Sigler, Paul Silhavy, Thomas Silver, Pamela Simons, Kai Simpson, Patricia Simpson, Robert Singh, Harinder Sive, Hazel Skene, Barbara Skowronski, Jacek Slack, Jonathan Smale, Steven Smith, Jim Smith, Mitchell Snyder, Michael Sollner-Webb, Barbara Sorger, Peter Speck, Nancy Speigelman, Bruce
Spradling, Allan Sprague, George St. Johnston, Daniel Stadtman, Theresa Stark, Mike Staskawicz, Brian Stellar, Hermann Stenlund, Arne Sternberg, Paul Sternglanz, Rolf Stillman, Bruce Strasser, Andreas Strickland, Sidney Struhl, Gary Struhl, Kevin Studer, Michelle Stunnenberg, Henk Surani, Azim Tessier-Lavigne, Marc Thomas, Christopher Thompson, Craig Thummel, Carl Tollervey, David Tomlinson, Andrew Treisman, Richard Tryggvason, Karl Tye, Bik-Kwoon Ullu, Elizabetta Van Aelst, Linda Van Dyke, Terry van Heyningen, Veronica Varmus, Harold Vennstrom, Bjorn Verma, Inder Vogt, Peter Wagner, Erwin Wahl, Geoffrey Walbot, Virginia Wasserman, Steven Weber, Klaus Weigel, Detlef Weinberg, Robert Weinert, Ted Weissman, Charles Weissman, Irving Wensink, Peter West, Stephen Westerfield, Monte Weston, Kathleen White, Eileen White, Rob Wickens, Marvin Wieczorek, Helmut Wieschaus, Eric Willison, Keith Winston, Fred Wisniewski, Henryk Witte, Owen Wolffe, Alan Wong, Winnie Wood, Richard Wormington, Michael Wright, Christopher Yamamoto, Keith Yanagida, Mitsuhiro Yaniv, Moshe
Yanofsky, Martin Young, Richard Yuspa, Stuart Zakian, Virginia Ziff, Edward Zinn, Kai
GENES & DEVELOPMENT 3221
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3222 GENES & DEVELOPMENT
Author Index, Volume 10 (1996) Abrams, J.M., 1773 Adams, J.M., 70 Adler, H.S., 1455 Aebersold, R., 1084 Aguilar-Cordova, E., 553 Ahringer, J., 1120 Akimani, H., 528 Alarcon, C.M., 279 Alexandre. C., 2003 Alexandropoulos, K., 1341 Algate, P.A., 1084 Allende, M.L., 3141 Alley, M.R.K., 1532 Alwine, J.C., 325, 1369 Alzhanova-Ericsson, A.T.,
2881 Amano, S., 1724 Amberg, D.C., 1608 Ammeter, G., 129 Amsterdam, A., 3141 Anderson, J.E., 1173 Andresen, J.M., 2903 Andrew, D.J., 103 Apone, L.M., 2368 Arber, S., 289 Ares, M., Jr., 220 Arndt, K.T., 1904 Arroyo, E., 1751 Asano, M., 1422 Ashley, T., 2411, 2423 Assa-Munt, N., 16 Aubry, L., 118 Azpiazu, N., 3183 Badiani, P., 2732 Bagni, C., 1411 Bai, Y., 2025 Baker, J.C., 1880 Baltimore, D., 963, 1341,
2401, 2411 Banerjee, U., 1194 Barberis, A., 2359 Bardwell, L., 2831 Barolo, S., 3195 Barrett, T., 2732 Basson, M., 1953 Baumeister, R., 1395 Beach, D., 1633 Beall, E.L., 921 Beard, C., 1008 Beaulieu, N., 1930 Becker, T., 3141 Behringer, R.R., 2577 Beijersbergen, R.L., 2969 Beiman, M., 2993 Belfort, M., 351, 2158 Bentley, N.J., 2423 Berget, S.M., 208 Bergstrom, D.E., 1260 Berk, A.J., 2491 Bermingham, J.R., Jr., 1751 Bernards, R., 2969 Beug, H., 2462 Biehs, B., 2922 Bier, E., 2922
Birchmeier, C., 1184 Bitgood, M.J., 647 Blackburn, E.H., 1822 Blackman, R.K., 1260 Blakely, G., 762 Blatter, E.E., 16 B6hm, T., 1516 Boeke, J.D., 620 Bogue, M.A., 553 Boise, L.H., 2621 Bommakanti, M., 129 Bonten, E., 3156 Boscheron, C., 1796 Bossard, P., 1670 Bouhidel, K., 1812 Bowman, T., 826 Brainerd, E.E., 2411, 2423 Brass, A.L., 2335 Breitwieser, W., 2179 Brewer, B.J., 1595 Brill, S.J., 2222 Brissette, J.L., 2212 Broach, J.R., 382, 1021 Brodbeck, C., 2707 Brody, M.S., 2265 Bronson, R.T., 1621, 1633,
2055, 2411 Brook, A., 2505 Brown, J.D., 2805 Brown, S.A., 1479 Brun, R.P., 974 Bryant, G.O., 2491 Brzoska, P.M., 2564 Buck, S.W., 1297 Bullrich, F., 1724 Bunker, C.A., 905 Burgeson, R.E., 1724 Burke, T.W., 711 Burley, S.K., 2491 Burson, L.M., 887 Cairns, B.R., 2117, 2131 Camper, S.A., 313 Cannon, K., 37 Cao, J., 1049 Cao, Z., 37 Cardenas, M.E., 279 Carey, M., 2540, 2769 Carlberg, K., 1084 Carlson, M., 3105 Caroni, P., 289 Cart, A.M., 2423 Carthew, R.W., 2167 Castaflo, I.B., 2564 Cate, R.L., 2577 Cech, T.R., 2870 Cepek, K.L., 2079 Chambon, P., 80, 2326 Chan, Y.R., 2055 Chang, H.C., 272 Chang, J., 777 Chao, D.T., 2859 Chasman, D.I., 2079 Chen, H., 2564 Chen, J., 974
Chen, J.-Y., 2326 Chen, P., 1773 Chen, P.-L., 2794 Chen, X., 2438 Chen, Y., 2794 Cheng, G., 963 Chi, T., 2540 Chin, W., 80 Chin-Sang, I.D., 2314 Christenson, E.R., 2423 Christiano, A.M., 1724 Christman, M.F., 2564 Chung, D., 3051 Clark, A.M., 118 Clarkin, K.C., 934 Cleghon, V., 566 Clurman, B.E., 1979 Clyman, J., 351 Cobrinik, D., 1633 Cocker, J.H., 1516 Coffer, P., 1455 Cohen, J.B., 338 Cohen, M., 129 Cohen-Fix, O., 3081 Cole, C.N., 1608 Coleman, J.R., 1670 Colot, H.V., 1699 Cook, J.G., 2831 Copeland, T.D., 566 Cornet, F., 1152 Cosgrove, D., 2981 Costantini, F., 154 Coursen, J.D., 1219 Crabtree, G.R., 2117 Craig, N.L., 2145 Crespo, P., 1455 Crompton, T., 948 Cygan, J.A., 1260 Daga, A., 1194 D'Agati, V.,- 154 Dahanukar, A., 2610 Dai, P., 528 Damania, B., 1369 Dancholt, B., 2881 Danska, J.S., 2038 Darlington, G.J., 804 Dash, A.B., 1858 Datar, S.A., 1966 Dausman, J., 1008 Davis, R.J., 2732 d'Azzo, A., 3156 De Baere, I., 755 Ddcimo, D., 80 DeArmond, S.J., 1736 DeBoy, R.T., 2145 Decatur, A.L., 2348 Degenstein, L., 165 Deng, K., 1657 Denis, G.V., 261 Desbarats, L., 447 Devine, S.E., 620 1)i Como, C.J., 1904 Di Cunto, F., 3065 Di Leonardo, A., 934
Dierich, A., 80 Diffley, J.F.X., 1516, 2819 Diller, J.D., 1595 Dodd, J.A., 887, 2551 Doe, C.Q., 3003 Doherty, D., 421 Dominski, Z., 3028 Donaldson, T., 2302 Donehower, L.A., 553 Dotto, G.P., 2212, 3065 Doucas, V., 196 Drouin, J., 1284 Du, W., 1206 Duboule, D., 2326 Dudek, H., 816 Dugich-Djordjevic, M.M.,
3129 Dull, M., 1382 Dumstrei, K., 1194 Dunphy, W.G., 1503 Duronio, R.J., 2505 Dyson, N., 1206, 1621, 1633,
2505 Eady, R.A.J., 1724 Eagelson, K., 1049 Ebright, R.H., 16 Eckhaus, M., 836 Eckner, R., 2478 Edgar, B.A., 1966 Edmondson, D.G., 1247 Eichele, G., 176 Eidemiller, J., 185 Eilers, M., 447 Eisenbeis, C.F., 2335 Elledge, S.J., 2632 Ellis, R., 974 Elmore, L., 1219 Endo, S., 1645 Ephrussi, A., 2179 Erdjument-Bromage, H., 1049 Errington, J., 794 Evans, R.M., 196, 974 Fangman, W.L., 1595 Fankhauser, C., 2707 Fantino, E., 887 Farifias, I., 1382 Farrell, S., 2359 Fay, D.S., 395 Feger, G., 421 Feld, R., 244 Ferguson, B.M., 1595 Ferguson, K.C., 1543 Fernandez-Salguero, P., 60 Feucht, A., 794 Field, D.J., 489 Fiering, S., 185 Filosi, N., 407 Finegold, M.J., 2577 Firtel, R.A., 118 Fischer, D., 1143 Fisher-Adams, G., 686 Fitzsimmons, D., 2198 Flaggs, G., 2423 Flesken-Nikitin, A., 1835
GENES & D E V E L O P M E N T 3223
Foiani, M., 395 Forman, B.M., 974 Fomerod, M., 3156 Forrester, K., 1219 Fox, C.H., 60 Frampton, J., 2720 Francois, V., 2922 Frasch, M., 3183 Fraser, P., 2894 Fredericks, W.J., 2067 Freedman, L.P., 129 Friedman, J.R., 2067 Friedman, K.L., 1595 Friend, S., 2382 Friesen, J.D., 489 Fritz, A., 2759 Fuchs, E., 165 Gaal, T., 16 Gagel, R.F., 208 Gaiano, N., 3141 Galceran, J., 1382 Gallagher, P.A., 2167 Gallie, B.L., 3051 Gansmuller, A., 80 Garrett, K., 1173 Gaskins, C., 118 Gasser, S.M., 1796 Gaubatz, S., 447 Gauthier, Y., 1284 Gayko, U., 566 G6rard, M., 2326 Geiduschek, E.P., 725 Gibson, M., 1219 Gilson, E., 1297, 1796 Girard, L., 1930 Gish, B., 1773 Gisselbrecht, S., 3003 G6mez-Skarmeta, J.L., 2935 G6decke, S., 1184 Godley, L.A., 836 Gonzalez, F.J., 60 Goodrich, L.V., 301 Gordon, J.I., 985 Gotta, M., 1796 Gourse, R.L., 16 Gozani, O., 244 Graf, T., 2720 Grallert, B., 2644 Grandal, I., 2038 Gray, S., 700 Greco, T.L., 313 Green, M.R., 261, 517, 2368 Gribnau, J., 2894 Grisham, J., 245 Grondona, J.M., 80 Gronemeyer, H., 2326 Gross, C.A., 3170 Grosschedl, R., 1382 Grossman, A.D., 2014 Grosveld, F., 2894 Grosveld, G., 3156 Groudine, M., 185, 1979 Grumbling, G., 2302 Grunkemeyer, J.A., 2981 Grunstein, M., 686, 1327 Gruszynski-DeFeo, E., 672
Gu, C., 2222 Gu, L., 826 Gualdi, R., 1670 Guermah, M., 2389 Guidos, C., 2038 Guo, L., 165 Gutkind, J.S., 1455 Ha, I., 3041 Haag, T.A., 672 Hacohen, N., 2912 Hafen, E., 2759 Haga, T., 1736 Hagman, J., 2198 Hagstrom, K., 3202 Hamada, Y., 1670 Hamer, J.E., 2696 Hammerschmidt, M., 647,
2452 Han, J., 461 Han, Z., 2732 Hanahan, D., 2105 Hanna, Z., 1930 Hannon, G., 1633 Hansen, S.K., 2903 Hara, Y., 60 Harkness, T.A.A., 686 Harland, R.M., 1880 Harlow, E., 1621, 1633 Harper, J.W., 1491 Harris, A.W., 2055 Harris, C.C., 1219 Hartenstein, V., 672 Hartley, L., 70 Harvey, R.P., 70 Hateboer, G., 2969 Hatini, V., 1467 Hawley, R.S., 2383 Hayashi, S., 659 Hayday, A.C., 948 Haynes, M., 220 Hazel, T.G., 3129 He, T.-C., 1945 Heid, p.J., 1543 Heintz, N., 2389 Heitman, J., 279 Henderson, D.W., 1455 Hengge-Aronis, R., 1143 Henry, M., 1233 Hentsch, B., 70 Hermiston, M.L., 985 Herzlinger, D., 1467 Hill, R.E., 435 Hinman, A., 2971 Hogaard, A., 1162 Hodsdon, W., 2198 Hoeijmakers, J.H.J., 1219 Hoekstra, M.F., 2423 Hoemann, C., 1930 Hoffman, E.S., 948 Hoffmann, A., 2389 Hofmann, F., 851, 2949 Hogan, B.L.M., 1580, 1657 Holmes, S.G., 1021 Holtzman, D.A., 2423 Hopkins, N., 3141 Hopper, A.K., 1608
3224 GENES & DEVELOPMENT
Hoppler, S., 2805 Horstmann, H., 2179 Horvitz, H.R., 578, 1073,
1289, 1953 Hou, D.-X., 528 Hsu, T., 1411 Hu, M.C.-T., 2251 Huang, E., 1433 Huang, M.T.F., 2038 Huang, X.-P., 2067 Huang, Y.-J., 351 Hudson, D.L., 1724 Huh, S.O., 1467 Hunter, W.J., 2981 Hwang, D.-Y., 338 Igel, H., 220 Imbalzano, A.N., 905, 1479 Ingham, P.W., 2003 Ingledue, T.C., III, 3028 Inostroza, J.A., 1049 Ip, Y.T., 2732 Irish, V.F., 1812 Isaac, D.D., 103 Ishii, S., 528 Ishov, A.M., 196 Izaurralde, E., 1683 Jacinto, A., 2003 Jacks, T., 1621, 1633, 2055 Jackson-Grusby, L., 1008 Jaenisch, R., 1008, 1991 Jallepalli, P.V., 541 Jan, L.Y., 421 Jan, Y.N., 421 Jarmolowski, A., 1683 Jayaraman, L., 2438 Jenni, M., 2759 Jensen, D.E., 2067 Jia, X., 16 Jiang, R., 3105 Jiang, Y.W., 604 Jiang, Z., 3051 Joazeiro, C.A.P., 725 Johe, K.K., 3129 Johnson, R.C., 2769 Johnson, R.L., 301 Jolicoeur, P., 1930 Jones, K.A., 37 Jones, N., 2289 Josso, N., 2577 Joyner, A.L., 3077 Juguilon, H., 196 Kablar, B., 1173 Kadonaga, J.T., 37, 711 Kadowaki, T., 3116 Kafatos, F.C., 1411 Kaiser, D., 740 Kalla, K.A., 1751 Kamimura, J., 2212 Kane, M.F., 407 Kanei-Ishii, C., 528 Kang, C.M., 2265 Karim, F.D., 272 Karlovich, C.A., 1194 Karrim, J., 2105 Kassavetis, G.A., 725 Kassis, J., 1108
Kastner, P., 80 Kataoka, Y., 659 Kauffmann, R.C., 2167 Kaufman, T.C., 176 Kaufmann, J., 873 Kawakami, K., 3141 Ke, N., 634 Keck, J.G., 37 Keegan, K.S., 2423 Kehrli, E., 2335 Kelly, T.J., 541 Kerkhoven, R.M., 2969 Kerr, K., 2600 Keys, D.A., 887, 2551 Kieser, A., 1455 Kim, J.B., 1096 Kim, J.M., 634 Kimelman, D., 1433 Kimsey, H., 740 Kimura, S., 60 Kingston, R.E., 905, 1479,
2782 Kinzler, K., 1945 Kirschner, M.W., 3081 Kiseleva, E., 2881 Kiyokawa, H., 3065 Klein, R., 2849 Klemm, J.D., 27 Klingensmith, J., 3116 Knauf, U., 2782 Knight, S.A.B., 1917 Knowles, G., 2038 Ko, L.J., 1054, 2438 Kobayashi, M., 1783 Koch, C., 129 Koff, A., 948, 3065 Kojima, T., 1645 Kolch, W., 1455 Kolodner, R., 407, 1433 Kondo, K., 1783 Kopp, J.B., 836 Kornak, J.M., 2981 Kornberg, R.D., 2131 Korsmeyer, S.J., 2859 Koshland, D., 3081 Kosman, D.J., 1917 Kowalczykowski, S.C., 1890 Kozak, C.A., 1930 Krall, L., 245 Krasnow, M., 2912 Kratochwil, K., 1382 Kraut, R., 659 Kremmer, E., 1455 Krezel, W., 80 Krishnan, V.V., 16 Kron, S.J., 2831 Kuempel, P., 1162 Kuo, A., 2117 Kwon, L.F., 1917 Kwon, Y.T., 816 Kyriakis, J., 2782 LabbG S., 1917 Labosky, P.A., 1657 Lagrange, T., 2657 Lai, E., 1467 Laird, P.W., 1008
Lamonerie, T., 1284 Lanct6t, C., 1284 Landsman, D., 1049 Lane, E.B., 1724 Lawrence, P.A., 3183 Lazazzera, B.A., 2014 Lee, B.-S., 887 Lee, D., 2212 Lee, M.-H., 129, 1621, 1633 Lee, M.S., 1233 Lee, T., 2912 Lee, W.-H., 1835, 1870, 2794 Lehmann, R., 3077 Lei, H., 1008 Leid, M., 80 Leigh, I.M., 1724 Leng, X., 1491 Leu, T.M.J., 948 Levin, P.A., 478 Levine, A.J., 2971 Levine, M., 700, 3195 Levinson, R.S., 2131 Levitt, P., 1049 Lewis, J.D., 1683 Li, B., 1310 Li, E., 1008 Li, J., 2212 Li, R., 70 Li, S., 1835 Li, S., 2167 Li, X.-Y., 517 Liaw, L., 1657 Lilly, M.A., 2514 Lira, S.-K., 154 Lin, C.-S., 154 Ling, X., 686 Linke, S.P., 934 Lints, T.J., 70 Lioubin, M.N., 1084 Liu, C.-Y., 1835 Liu, M., 129 Liu, X.-D., 592 Liu, Y., 1395 Livingston, D.M., 851, 2478,
2949 Lobel, L., 2189 Losick, R., 478, 2348 Lou, H., 208 Louarn, J., 1152 Louarn, J.-M., 1152 Lowell, C.A., 1845 Lu, H.-C., 176 Lu, J., 2222 Lu, Q., 1327 Lundblad, V., 3094 Lupold, S.E., 1219 Lustig, A.J., 1310 Lutz, B., 176 Lutz, C.S., 325 Lynch, K.W., 2089 Lyons, I., 70 Ma, X.-J., 1327 Macdonald, P.M., 2600 Madden, K., 777 Magis, W., 185 Magnin, T., 794
Maillet, L., 1796 Maira, S.-M., 2198 Majerus, P.W., 1051 Maniar, H.S., 2222 Maniatis, T., 1356, 2089 Manley, I.L., 325, 862, 1569,
2588 Marcand, S., 1297, 1796 Marini, F., 395 Mark, M., 80 Markussen, F.-H., 2179 Marsischky, G.T., 407 Martel, L.S., 2491 Martelli, F., 2949 Marth, J.D., 3051 Martin, D.I.K., 185 Marzluff, W.F., 3028 Matsui, W., 1271 Mattaj, I.W., 1683 Matzuk, M.M., 2577 Maul, G.G., 196 McEachern, M.]., 1822 McGonigle, B., 1812 McGrath, J.A., 1724 McGuigan, C., 1683 McKay, R.D.G., 3129 McKnight, S.L., 367 McLean, W.H.I., 1724 McMahon, A.P., 313, 647,
2452 McMahon, I.A., 301,313 McMillan, J.R., 1724 Meehan, D.T., 2981 Megeney, L.A., 1173 Mellerick, D.M., 1108 Merli, C., 1260 Mermelstein, F., 1049 Meyer, C.F., 2251 Meyn, M.S., 2411, 2423 Michaud, N.R., 2.684 Michelson, A.M., 3003 Milenkovic, L., 301 Millar, J.B.A., 2289 Miller, D., 176 Miller, J.R., 1433, 2527 Milliman, C.L., 2859 Minichiello, L., 2849 Minn, AJ., 2621 Mischak, H., 1455 Mishina, Y, 2577 Missero, C., 3065 Mitchell, P., 502 Miyake, T., 1783 Mlodzik, M., 50 Modha, D., 461 Modolell, J., 2935 Montell, D.J., 2912 Moon, R.T., 1433, 2527, 2805 Moose, S.P., 3018 Moretti, P., 1297 Morris, D.K., 3094 Morrison, D.K., 566, 2684 Moss, S.B., 2423 Mueller, J.E., 351, 2158 Muffler, A., 1143 Mukai, S., 1621
Mullen, J.R., 2222 Muller, M., 3202 Muller, T., 3129 Mulligan, G., 1621, 1633 Murayama, A., 1783 Murphy, M., 2971 Murthy, K.G.K., 325 Mushinski, I.F., 1455 Nacht, M., 2055 Nagappan, O., 1162 Naik, P., 2105 Nakanishi, M., 804 Nasmyth, K., 129, 1516 Navas, T., 2632 Neilson, E.G., 2067 Ness, S.A., 1858 Neville, M., 220 Nevins, J.R., 1422 Newhouse, M.W., 313 Newton, E.M., 2782 Nguyen, T.T., 887 Nickels, J.T., 382 Nielsen, M., 1162 Nikitin, A.Yu, 1870 Nikolic, M., 816 Nogi, Y., 887 Nomura, M., 887, 2551 Nordstrom, W., 1773 Norris, J.L., 862 Nuez, B., 2894 Nurse, P., 2644 Nyland, S.V.M., 1595 O'Connell, S., 1751 O'Connor, J.P., 325 Oda, H., 659 Odenwald, W.F., 1108 O'Farrell, P.H., 2505 Oft, M., 2462 Ohno, M., 997 Olde, B., 1108 Oldread, E., 2478 Oliner, J.D., 2903 Omatyar, L., 672 Oren, M., 826 Orphanides, G., 2657 Orrico, F.C., 1858 Owaribe, K., 1724 Owen, M.J., 948 Owens, J., 836 Pabo, C.O., 27 Paglino, l.J., 836 Panning, B., 1991 Parker, M.M., 351 Parker, S.B., 1491 Passoni, L., 948 Patra, D., 1503 Patte, J., 1152 Paull, T.T., 2769 Pazin, M.J., 37 Peli, l., 2462 Perez, D., 461 Perkins, L.A., 566 Perrimon, N., 566, 3116 Peters, J.-M., 3081 Petfalski, E., 502 Philipova, D., 2222
Philipsen, S., 2894 Phillips, R.A., 3051 Piatti, S., 1516 Pineau, T., 60 Plasterk, R.H.A., 755 Plug, A.W., 2423 Polyak, K., 1945 Powell, F.L., 1751 Price, C.W., 2265 Pritchard, D.K., 1131 Prives, C., 1054, 2438 Prusiner, S.B., 1736 Ptashne, M., 2359 Pulkkinen, L., 1724 Qiu, W.R., 2251 Quinn, J.C., 435 Ramos, Y.F.M., 816 Ramqvist, T., 2720 Rao, L., 461 Rauscher, F.J., III, 2067 Ray, R.P., 1711 Reed, R., 244 Reese, J.C., 2368 Reichmann, E., 2462 Reinberg, D., 1049, 2657 Rey, R., 2577 Riesgo-Escovar, J.R., 2759 Riethmacher, D., 1184 Riley, D.J., 2794 Rio, D.C., 921 Roberts, J.M., 1979 Roeder, R.G., 2389 Roemer, T., 777 Rohrschneider, L.R., 1084 Romo, A., 196 Rosbash, M., 1699 Rosenfeld, M.G., 1751 Ross, W., 16 Roth, D.B., 553 Roth, S.Y., 1247 Rothman, J.H., 1543 Rouvi~re, P., 3170 Rubin, G.M., 272, 2684 Rudaz, C., 2462 Rudnicki, M.A., 1173 Rugg, E.L., 1724 Rusconi, C.P., 2870 Russell, P., 2276 Ruvkun, G., 1395, 3041 Saavedra, C., 1608 Sabbatini, P., 461 Sadoff, B.U., 2564 Sager, B.M., 2237 Saigo, K., 1645 Samuels, M., 2289 Samuelson, G.C., 2981 Sanchez, Y., 2632 Sawa, H., 2189 Sayers, R., 2981 Scalzo, D., 185 Schatz, D.G., 948 Schedl, P., 3202 Schek, N., 325 Scherer, S.S., 1751 Schier, A.F., 3077 Schleiffer, A., 129
GENES & DEVELOPMENT 3225
Schlissel, M., 2055 Schneider, R.J., 1557 Schnepp, B., 2302 Schfipbach, T., 1711 Schubiger, G., 1131 Schultz, M.C., 686 Schwarz, H., 2462 Scott, M.P., 301 Segall, J.E., 118 Segil, N., 2389 Seicher, D.W., 2067 Seitz, T., 1455 Serbedzija, G.N., 2452 Shaham, S., 578, 1073 Shao, J., 873 Shapiro, L., 1532 Sharp, P.A., 2079 Sheaff, R.J., 1979 Sheridan, P.L., 37 Sherratt, D., 762 Shieh, J.-C., 2289 Shilo, B.-Z., 93, 2993 Shimura, Y., 997 Shiozaki, K., 2276 Shore, D., 1297 Shvarts, A., 2969 Silver, P.A., 1233 Simanis, V., 2707 Simard, C., 1930 Simcox, A., 2302 Simkovich, N., 2359 Singh, H., 2335 Sisco, P.H., 3018 Skeath, J.B., 3003 Slack, F.J., 740 Sluss, H.K., 2732 Smale, S.T., 873 Smibert, C.A., 2600 Smith, D., 2158 Smith, F.J.D., 1724 Smith, J.R., 804 Smith, M.M., 1247 Snyder, M., 777 S~gaard-Andersen, L., 740 Soares, V.C., 1467 Sohrmann, M., 2707 Solomon, J.M., 2014 Solomon, N.M., 272 Sonnenberg-Riethmacher, E.,
1184
Soriano, P., 1845 Spence, A.M., 2314 Spiegelman, B.M., 974, 1096 Spradling, A.C., 2514 St-Arnaud, R., 1763 Starr, D.B., 1271 Steffan, J.S., 2551 Stepanova, L., 1491 Stephens, C., 1532 Stern, D.F., 395 Stillman, D.J., 604 Storb, U., 2335 Strasser, A., 2055 Stutz, F., 1699 Sun, X., 2881 Sun, Z., 395
Sutherland, J.D., 1411 Suzuki, T., 1783 Symington, L.S., 2025 Symonds, H., 826 Szymanski, P., 3195 Tacke, R., 1569 Takada, S., 313 Takagaki, Y., 2588 Takahashi, F., 1645 Takahashi, T., 528 Takahisa, M., 1783 Takeda, T., 2289 Takeichi, M., 659 Talbot, W.S., 3077 Tan, T.-H., 2251 Tanaka, Y., 528 Tang, H., 16 Taylor, D., 2732 Taylor, E.M., 2423 Tecklenburg, M., 1162 Telling, G.C., 1736 Tempst, P., 1049 Tepass, U., 672 Therrien, M., 272, 1284, 2684 Thiele, D.J., 592, 1917 Thomas, J.R., 1271 Thompson, C.B., 2621 Thorner, J., 2831 Thress, K., 1979 Timchenko, N.A., 804 Tjian, R., 50, 2903 T6r6k, T., 672 Toda, T., 2289 Togashi, S., 1783 Tollervey, D., 502 Tontonoz, P., 974 Toone, W.M., 2289 Torchia, M., 1736 Torres, M., 1443 Tracy, R.B., 1890 Tremblay, J.l., 1284 Tremblay, P., 1736 Trimborn, T., 2894 Tsai, L.-H., 816 Tsai, S., 1084 Tsou, A., 934 Tucker, K.L., 1008 Tung, K.-S., 1608 Ueda, R., 1783 Uemura, T., 659 Uitto, J., 1724 van der Spoel, A., 3156 Van Dyke, T., 245, 826 Varmus, H.E., 836 Vermeulen, W., 1219 Verrijzer, C.P., 873 Vidal, M., 1206 Vincent, J.-P., 3183 Virbasius, C.-M.A., 2368 Virta-Pearlman, V., 3094 Visa, N., 2881 Vogelstein, B., 1945 Volk, T., 2993 Vos, J.C., 755 Voytas, D.F., 634 Vu, L., 887
Wade, M., 245 Wahl, G.M., 934 Waldman, T., 1945 Walter, B., 1184 Walters, M.C., 185 Wang, J., 220 Wang, J., 2588 Wang, K., 2859 Wang, W., 2117 Wang, X., 2251 Wang, X.W., 1219 Wang, Z., 2949 Wang, Z-F., 3028 Ward, J.M., 60 Wassarman, D.A., 272 Wasylyk, B., 2198 Weinberg, R.A., 1633 Weitzman, M.D., 196 Weizman, 1., 93 Wells, S.E., 220 West, J.D., 435 Weston, K., 2732 Wharton, R.P., 1422, 2610 Wheat, W., 2198 White, E., 1,461 Whitfield, M.L., 3028 Wightman, B., 3041 Wijgerde, M., 2894 Wilde, M., 804 Wilder, E., 3116 Wilk, R., 93 Wilkinson, M.G., 2289 Williams, B.O., 1621 Williams, C.J., 2038 Wilson, J.E., 2600 Wolkow, C.A., 2145 Wong, M.H., 985 Wright, R., 1532 Wu, H., 245 Wu, Y., 2359 Wurtz, T., 2881 Xie, J.-E., 1206 Xiong, Y., 245 Xu, G., 1219 Xu, J.-R., 2696 Xu, Y., 2401, 2411 Xuc, D., 1073 Xue, Y., 2117 Yamamoto, K.R., 1271, 2131 Yang, X., 2265 Yao, T.-P., 2478 Yasukawa, T., 528 Yeh, H., 1219 Yeung, K., 1049 Yin, C., 826 Yin, X.-M., 2859 Yokomori, K., 50 Yost, C., 1443 Yotov, W.V., 1763 Younger-Shepherd, S., 421 Yudkin, M.D., 794 Yueh, A., 1557 Zakany, J., 2326 Zachary, K., 3116 Zacksenhaus, E., 3051 Zaret, K.S., 1670
Zeidler, M.P., 50 Zeng, Y., 1835 Zhang, J., 2167 Zhang, S.-D., 1108 Zhao, G.-Q., 1657 Zheng, M., 1670 Zhou, J., 3195 Zhou, S., 2117, 2903 Zhu, C., 553 Zou, S., 634 Zuo, P., 1356 Zweiger, G., 1532
3226 GENES & DEVELOPMENT
Subject Index, Volume 10 (1996)
ACT3 gene, epigenetic effects on yeast transcription caused by muta- tions (Jiang and Stillman), 604- 619
Actin, LIM-mediated binding of MLP to cytoskeleton (Arber and Ca- roni), 289-300
Actin-related protein, epigenetic effects on yeast transcription caused by mutations (Jiang and Stillman), 604-619
Activating transcription factor-2 Spcl regulation of S. pombe homolog
Atfl (Shiozaki and Russell), 2276-2288
role of DNA-binding domain as inhib- itory region (Li and Green), 517- 527
Activation, transcriptional by c, CTD-DNA interactions in E. coli
(Gaal et al.), 16-26 CBP as a coactivator of c-Myb (Dai et
al.), 528-540 cell-cycle regulation of SBF binding
(Koch et at.), 129-141 during Drosophila embryogenesis
(Pritchard and Schubiger), 1131-1142
functional TBP epitopes for Pol II ac- tivity (Bryant et al.), 2491-2504
inhibition by the ATF-2 DNA-binding domain (Li and Green), 517-527
regulation of transcriptional pausing on nucleosomal templates (Brown et al.), 1479-1490
role of TFIIA-TFIID complex forma- tion in gene activation (Chi and Carey), 2540-2550
specificity of Myc (Desbarats et al.), 447-460
Activators, gene-specific, findings pre- sented at Cold Spring Harbor meeting (McKnight), 367-381 Meeting commentary
Activin, participation of Madr2 in signal- ing pathway (Baker and Har- land), 1880-1889
Activity, context-dependent, altered in- tracellular receptor activation (Starr et al.), 1271-1283
ADD1, role in adipocyte differentiation (Kim and Spiegelman), 1096- 1107
Adenine DNA methyltransferases, CcrM as target of Lon protease in C. crescentus (Wright et al.), 1532-1542
Adenovirus POD organization and viral DNA rep-
lication (Doucas et al.), 196- 207
regulation of E2F degradation by trans-
forming proteins (Hateboer et al.), 2960-2970
use of ribosome jumping for transla- tion of late mRNAs (Yueh and Schneider), 1557-1567
Adhesion proteins, role of plx in tracheal function (Zhang et al.l, 1108- 1119
Adipogenesis. See also Differentiation, adipocyte
differential activity of multiple PPAR isoforrns (Brun et al.), 974-984
role of Rb interaction with C/EBPs in adipocyte terminal differentia- tion (Chen et al.), 2794--2804
Adipose tissue, differential adipogenic ac- tivity of multiple PPAR isoforrns (Bran et al.), 974-984
AINTEGUMENTA, similarity of maize Glossyl5 (Moose and Sisco), 3018-3027
Alport syndrome, COL4A3-deficient mice as model (Cosgrove et al.), 2981- 2992
AML1, homologous domains found in Drosophila Lozenge (Daga et al.), 1194-1205
Anaphase, regulation in S. cerevisiae by APC-dependent degradation of Pdslp (Cohen-Fix et al.), 3081- 3093
Anaphase-promoting complex, role in Pdslp degradation in {Cohen- Fix et al.), 3081-3093
Anchoring site, binding by U2 snRNP proteins (Gozani et al.), 233-243
Anti-cancer agents, p53-dependent cell cycle arrest induced by ribonu- cleotide depletion (Linke et al.), 934-947
Anticodon, as signal sequence for tRNA import into mitochondria (Rusconi and Cech), 2870-2880
Antimetabolites, induction of p53-de- pendent cell-cycle arrest by ri- bonucleotide depletion (Linke et al.), 934-947
Antisigma factor, interaction of SpoIIAB with cr in B. subtilis (Decatur and Losick), 2348-2358
APC. See Anaphase-promoting complex APETALA2, similarity of maize Glossyl 5
(Moose and Sisco), 3018-3027 APETALA3, nuclear colocalization with
PISTILLATA (McGonigle et al.), 1812-1821
Apoptosis. See also Programmed cell death
Bcl-x L and p53 in mitotic checkpoint control (Minn et al.), 2621-2631
BID as novel death agonist possessing only a BH3 domain (Wang et al.), 2859-2869
effects of wild-type p53 transgene ex-
pression (Godley et al.), 836- 850
functional interaction of E1B 19K with Bax (Han et al.), 461-477
genetic determinants of p53 induction (Polyak et al.), 1945-1952; Erra- tum, 2818
induction by ectopic E2F expression in Drosophila (Asano et al.), 1422- 1432
negative regulation of MAP4 expres- sion by p53 (Murphy et al.), 2971-2980
opposing cell-death activities in C. el- egans neurons (Shaham and Horvitz), 578-591
p53 levels and extent of tumor cell re- sponse (Chen et al.), 2438-2451
in plO7-null mice (Lee et al.), 1621- 1632
in Rb +/- mice (Nikitin and Lee), 1870-1879
regulation of skeletal muscle cell pro- liferation by Rb (Zackenhaus et al.}, 3051-3064
regulators and pathways (White), 1-15 Review
rise and fall during multistage tumor- igenesis (Naik et al.), 2105-2116
role of grim in Drosophila (Chen et al.),
1773-1782 p53 (Ko and Prives), 1054--1072 Re-
view TrkB and TrkC in promoting neuron
survival (Minichello and Klein), 2849-2858
XPB and XPD in p53-dependent pathway (Wang et al.), 1219- 1232
substrate specificities of CED-3/ICE- like proteases (Xue et al.), 1073- 1083
suppression by E26 v-Myb (Frampton et al.), 2720-2731
tissue-specific inactivation of p53 tu- mor suppression in mice (Bow- man et al.1, 826--835
up-regulation by dominant interfering Myb (Taylor et al.), 2732-2744
Appressorium, formation during rice blast fungus M. grisea infection (Xu and Hamer), 2696-2706
Arabidopsis, nuclear colocalization of APETALA3 and PISTILLATA (McGonigle et al.), 1812-1821
araucan, positive regulation of by Dpp and Ci during wing patterning (G6mez-Skarmeta and Mod- olell), 2935-2945
Arches, branchial, role of pescadillo de- velopment in zebrafish (Allende et al.), 3141-3155
ASF. See ASF/SF2
GENES & DEVELOPMENT 3227
ASF/SF2, role in activation of polyadenylation by in-
tron enhancer (Lou et al.), 208- 219
cell viability (Wang et al.), 2588-2599 in splicing (Manley and Tacke), 1569-
1579 Review Asymmetric cell division. See Cell divi-
sion, asymmetric Asymmetry, coupling of cell lineage
asymmetry with transcription of unc-86 (Baumeister et al.), 1395-1410
Ataxia telangiectasia. See ATM Atf-1, regulation by Spcl in S. pombe
(Shiozaki and Russell), 2276- 2288
ATF2. See Activating transcription fac- tor-2
ATM association with meiotically pairing
chromosomes (Keegan et al.), 2423-2437
effects of gene inactivation in mice (Xu et al.), 2411-2422
role in cell-cycle regulation (Xu and Balti-
more), 2401-2410 different cell types and functional
links to p53 (Hawley and Friend), 2383-2388 Review
Atr, association with meiotically pairing chromosomes (Keegan et al.), 2423-2437
Attenuator, Fab-7 as boundary element in Drosophila
(Zhou et al.), 3195-3201 as chromatin domain boundary in
Drosophila (Hagstrom et al.), 3202-3215
Axial growth, role of Axl2p in bud-site selection in yeast (Roemer et al.), 777-793
Axis formation, role of [3-catenin and Xgsk-3 in Xenopus (Yost et al.), 1443-1454
AXL2, role in axial growth site selection in yeast (Roemer et al.), 777- 793
B
B cells Pax-5 recruitment of Ets proteins to
mb-1 promoter (Fitzsimmons et al.), 2198-2211
proteins, sequence-specific DNA bind- ing of POU domain coactivator OCA-B (Cepek et al.), 2079- 2088
role of p300/CBP and bHLH proteins in differentiation (Eckner et al.), 2478-2490
Bacillus subtilis
bifunctionality of SpoIIE in asymmet- ric cell division and cell-specific transcription (Feucht et al.), 794-803
bipolar localization of FtsZ (Levin and Losick), 478-488
interaction of SpoIIAB with (r F (Deca- tur and Losick), 2348-2358
role of extracellular peptide in differ- ent development pathways (So- lomon et al.), 2014-2024
signaling by serine kinases and phos- phatases in response to stress (Yang et al.), 2265-2275
BAFs. See BRGl-associated factors bagpipe, role in segmentation and speci-
fication of Drosophila meso- derm (Azpiazu et al.), 3183- 3194
Bar, positive regulation by Drosophila Lozenge (Daga et al.), 1194- 1205
Base pairing, of U2 and U6 snRNAs dur- ing splicing (Field and Friesen), 489-501
Basement membrane, effects of collagen COL4A3 gene inactivation in mice (Cosgrove et al.), 2981- 2992
basket, as encoding Drosophila JNK (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.1, 2759- 2768
Bax interaction with E1B 19K (Han et al.),
461-477 up-regulation by p53 (Ko and Prives),
1054-1072 Review Bcl-2 family
functional interaction of E1B 19K with Bax (Han et al.I, 461--477
role in apoptosis (White), 1-15 Review cell-death activities in developing C.
elegans neurons (Shaham and Horvitz), 578-591
BcI-x L BID as novel death agonist possessing
only a BH3 domain (Wang et al.), 2859-2869
regulation of apoptosis during multistage tumori-
genesis [Naik et al.), 2105-2116 bcl-2 by dominant interfering Myb
(Taylor et al.), 2732-2744 role in mitotic checkpoint control
(Minn et al.), 2621-2631 up-regulation of bcl-2 by E26 v-Myb
(Frampton et al.), 2720-2731 Belousov-Zhabotinsky reaction, propa-
gation of traveling waves (Sager), 2237-2250 Review
~-Catenin perturbation of distribution by forced
expression of E-cadherin (Her- miston et al.I, 985-996
regulation by Xgsk-3 (Yost et al.), 1443-1454
role in signal transduction during em- bryogenesis (Miller and Moon), 2527-2539 Review
B-Globin, role of EKLF in human gene competition (Wijgerde et al.), 2894-2902
[3-Globin 5'HS2 enhancer, in the study of position-effect variegation (Wai- ters et al.), 185-195
BH3 domain, in novel death agonist BID (Wang et al.), 2859-2869
bHLH proteins. See Helix-loop-helix pro- teins, basic
bicoid, novel related homeo box factor Ptxl (Lamonerie et al.), 1284- 1295
BID, novel death agonist possessing only a BH3 domain (Wang et al.), 2859-2869
Bithorax complex, Fab-7 attenuation of enhancer-promoter in-
teractions in Drosophila (Zhou et al.), 3195-3201
chromatin domain boundary in Droso- phila (Hagstrom et al.), 3202- 3215
BMP-4, activation of Lefl expression (Kratochwil et al.), 1382-1394
Bmp4, regulation by zebrafish dino and swirl (Hammerschmidt et al.), 2452-2461
BMPs. See Bone morphogenetic proteins Bone morphogenetic proteins
regulation of Bmp4 by dino and swirl in zebrafish (Hammerschmidt et al.), 2452-2461
role in embryonic development (Hogan), 1580-1594 Review
role of Bmp8b in spermatogenesis and fertility in mice (Zhao et al.L 1657-1669
Boundary elements, Fab-7 attenuation of enhancer-promoter in-
teractions in Drosophila (Zhou et al.), 3195-3201
chromatin domain boundary in Droso- phila (Hagstrom et al.), 3202- 3215
Branchial arches. See Arches, branchial Branchpoint sequences, binding up-
stream by U2 snRNP proteins and spliceosome assembly (Goz- ani et al.), 233-243
Brcal, effects of gene inactivation in mice (Liu et al.), 1835-1843
Breathless, role in patterning cell migra- tion and branching in Droso- phila (Lee et al.), 2912-2921
BRGl-associated factors, similarity to yeast SWI/SNF factors (Wang et al.), 2117-2130
BSAP, recruitment of Ets proteins to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211
3228 GENES & DEVELOPMENT
Bud site inhibition of ATF-2 activation by its
DNA-binding domain (Li and Green), 517-527
role of Axl2p in selection (Roemer et al.), 777-793
bZIP protein. See Leucine zipper protein, basic
C
C-factor. See C-signaling C-signaling
branched pathway in Myxococcus (Sogaard-Andersen et al.), 740- 754
traveling wave propagation in Myxo- coccus morphogenesis (Sager), 2237-2250 Review
c-Jun amino-terminal kinases activation by HPK1 (Hu et al.), 2251-
2264 Drosophila pathway mediating mor-
phogenesis and an immune re- sponse (Sluss et al.), 2745-2758
regulation of Atfl by Styl in S. pombe (Wilkinson et al.), 2289-2301
c-Myb, role of EVES motif in regulation (Dash et al.), 1858-1869
c-myc collaboration with Notch l for onco-
genesis (Girard et al.), 1930- 1944
specificity in gene activation by Myc (Desbarats et al.), 447-460
c-ros, role of in epithelial development (Sonnenberg-Riethmacher et al.), 1184-1193
C-SrC
effects of gene disruptions in mice (Lowell and Soriano), 1845- 1857 Review
regulation of eye development by re- lated Drosophila gene Dsrc41 (Takahashi et al.), 1645-1656
C/EBPs. See CCAAT/enhancer-binding proteins
Cadherins colocalization of Drosophila Dsrc41
and DE-cadherin in developing eyes (Takahashi et al.), 1645- 1656
role in intestinal epithelial cell migra- tion (Hermiston et al.), 985-996
Caenorhabditis elegans coupling of cell lineage asymmetry
with unc-86 transcription (Bau- meister et al.), 1395-1410
in vitro transposition of Tel (Vos et al.), 755-761
opposing cell-death activities in devel- oping neurons (Shaham and Horvitz), 578-591
posterior patterning by vab-7 (Ahr- inger), 1120-1130
role of FEM-2 in sex determination (Chin-
Sang and Spence), 2314-2325 lin-14 3' UTR in down-regulation of
translation (Ha et al.), 3041- 3050
lin-17 in asymmetric cell division in (Sawa et al.), 2189-2197
sere-4 in neuronal and mesodermal development (Basson and Hor- vitz), 1953-1965
SL1 trans-spliced leader RNA in em- bryogenesis (Ferguson et al.), 1543-1556
substrate specificities of CED-3/ICE- like proteases (Xue et al.), 1073- 1083
Calcitonin alternative splicing of pre-mRNA (Lou
et al.), 208-219 gene-related peptide, generation
through alternative splicing of calcitonin pre-mRNA (Lou et al.), 208-219
cAMP. See Cyclic AMP Cancer. See also Carcinogenesis; Onco-
genesis; Specific oncogenes; Tu- morigenesis
ATM as susceptibility gene (Hawley and Friend), 2383-2388 Re- view
breast, effects of Brcal gene inactiva- tion in mice (Liu et al.), 1835- 1843
p53-dependent cell cycle arrest in- duced by ribonucleotide deple- tion (Linke et al.), 934-947
rearrangement of Notchl in mouse thymomas in MMTV/myc transgenic mice (Girard et al.}, 1930-1944
redundancy of MSH3 and MSH6 in MSH2-dependent mismatch re- pair (Marsischky et al.), 407- 420
tissue-specific inactivation of p53 tu- mor suppression in mice (Bow- man et al.), 826-835
Cap-binding complex, nuclear Mudl3p as yeast homolog of CBP20
(Colot et al.), 1699-1708 role in pre-mRNA recognition and
splicing (Lewis et al.), 1683- 1698
Cap-binding protein, requirement for ri- bosome jumping in virus-in- fected and heat-shocked cells (Yueh and Schneider), 1557- 1567
Cap-prevented recombination. See Re- combination, cap-prevented
Carboxy-terminal domain, role in Pol II transcription (Orphanides et aL), 2657-2683 Review
Carcinogenesis, neuroendocrine role of Rb (Nikitin and Lee), 1870-1879
Caulobacter crescentus, role of Lon pro- tease in cell-cycle control of DNA methylation (Wright et al.), 1532-1542
caupolican, positive regulation of by Dpp and Ci during wing pat- terning (G6mez-Skarmeta and Modolell), 2935-2945
CBC. See Cap-binding complex, nuclear CBP. See CREB-binding protein CBP20, identification of yeast homolog
Mudl3p (Colot et al.), 1699- 1708
CCAAT/enhancer-binding proteins, role of
C/EBP-c~ in elevation of p21 (Tim- chenko et al.), 804--815
interaction with Rb in adipocyte ter- minal differentiation (Chen et al.), 2794-2804
CcrM, as target of Lon protease in Caw lobacter (Wright et al.), 1532- 1542
CD40, role of TANK in CD40L-medi- ated NF-KB activation (Cheng and Baltimore), 963-973
Cdc2 kinase, inhibition by Rum1 (Jalle- palli and Kelly), 541-552
Cdc2/cyclin B complexes, regulation by Xenopus Sucl homolog Xe-p9 (Patra and Dunphy), 1503-151
Cdc6, role in promoting replication during the cell
cylce (Piatti et al), 1516-1531 regulation of eukaryotic DNA replica-
tion (Diffley), 2819-2830 Review Cdc7, role in regulation of eukaryotic
DNA replication (Diffley), 2819-2830 Review
Cdcl0, AXL2 as high copy suppressor in spa2~ cdcl0-10 mutant strains (Roemer et al.), 777-793
Cdc 18, interaction with Rum 1 (Jallepalli and Kelly), 541-552
Cdc25, degradation of maternal mRNAs in maternal/zygotic transition (Edgar and Datar), 1966-1977
Cdc28p, role in regulation of eukaryotic DNA replication (Diffley), 2819-2830 Review
CDC37, encoding of protein kinase-tar- geting subunit of Hsp90 by mammalian homolog (Stepa- nova et al.), 1491-1502
CDC55, as encoding the regulatory sub- unit of ceramide-activated pro- tein phosphatase in S. cerevi- siae (Nickels and Broach), 382- 394
CDK inhibitors. See Cyclin-dependent kinase inhibitors
cdk2 regulation of cyclin E turnover by the
ubiquitin pathway (Clurman et al.), 1979-1990
role in control of pRB and E2F function
GENES & DEVELOPMENT 3229
during GI exit (Hofmann and Livingston), 851-861
cdk3, dominant-negative inhibition of E2F-1 in Rb-independent man- ner (Hofmann and Livingston), 851-861
cdk5, regulation of neurite outgrowth (Nikolic et al.), 816-825
CDKs. See Cyclin-dependent kinases CED-3, substrate specificities of ICE-like
proteases (Xue et al.), 1073--1083 ced-3, role in cell-death activities in de-
veloping C. elegans neurons (Shaham and Horvitz), 578-591
cecl-4, role in cell-death activities in de- veloping C. elegans neurons (Shaham and Horvitz), 578-591
cecl-9, role in cell-death activities in de- veloping C. elegans neurons (Shaham and Horvitz), 578-591
Cell adhesion, role of cadherins in intesti-
nal epithelium (Hermiston et al.1, 985-996
cycle arrest from p21 overexpression in
transgenic mice (Wu et al.), 245-260
arrest induced by ribonucleotide de- pletion (Linke et al.), 934-947
Bcl-x L and p53 in mitotic check- point control (Minn et al.), 2621-2631
cdk-dependent cyclin E ubiquitina- tion (Clurman et al.), 1979- 1990
cdk2 and cdk3 action in G 1 IHof- mann and Livingston), 851-861
ceramide-activated protein phos- phatase mediates ceramidedn- duced G L arrest in Saccharomy- ces cerevisiae (Nickels and Broach), 382-394
coincident regulation with clonality during T-cell receptor develop- ment (Hoffman et al.I, 948-962
cyclin E requirement for E2F-in- duced S phase (Duronio et al.), 2505-2513
determinants of late origin activa- tion in yeast (Friedman et al.), 1595-1607
induction of S phase by ectopic E2F expression in Drosophila (Asano et al.), 1422-1432
influence of p53 levels on arrest (Chen et al.), 2438-2451
modulators of histone function in yeast (Ma et al.), 1327-1340
p53-dependent arrest induced by ri- bonucleotide depletion (Linke et al.), 934-947
parallel sensory branches for DNA damage signaling in S. cerevi- siae (Navas et al.), 2632-2643
protection of E2F-1 from ubiquitin-
proteasome degradation path- way by Rb (Hofmann et al.), 2949-2959
regulation by ATM (Xu and Baltimore),
2401-2410 of E2F degradation by Rb family
proteins and adenovirus trans- forming proteins (Hateboer et al.), 2960--2970
of S-phase onset by fission yeast ORC1 homolog orpl (Grallert and Nurse), 2644-2654
of SBF binding (Koch et al.), 129- 141
of skeletal muscle cell prolifera- tion by Rb (Zackenhaus et al.), 3051-3064
by Xenopus Sucl homolog Xe-p9 (Patra and Dunphy), 1503-151
requirement for yeast TAFn90 (Apone et al.), 2368-2380
role of Lon protease in control of DNA
methylation (Wright et al.), 1532-1542
p21 in keratinocyte growth and differentiation (Missero et al.), 3065-3075
p53 (Ko and Prives), 1054-1072 Review
rapamycin-sensitive TOR func- tion in yeast (Alarcon et al.), 279-288
Rb interaction with C/EBPs in ad- ipocyte terminal differentiation (Chen et al.), 2794-2804
Rum 1 inhibition of Cdc2 kinase and interaction with Cdcl8 (Jalle- palli and Kelly), 541-552
termination of early program in Drosophila embryogenesis (Ed- gar and Datar), 1966-1977
timing of replication promotion by Cdc6 (Piatti et al.), 1516-1531
truncation of S phase during the Drosophila endocycle (Lilly and Spradling), 251 4-2526
division asymmetric
coupling of cell lineage asymme- try with unc-86 transcription (Baumeister et al.), 1395-1410
role of lin-17 in C. elegans (Sawa et al.), 2189-2197
role of SpoIIE in Bacillus subtilis (Feucht et al.), 794-803
bipolar localization of FtsZ in Bacil- lus subtilis (Levin and Losick), 478-488
fate cadherins role in intestinal epitheli-
al cell migration (Hermiston et al.), 985-996
signal transduction role through ~-catenin during embryogenesis
(Miller and Moon), 2527-2539 Review
growth defects in ATM-deficient mice (Xu
et al.), 2411-2422 interactions, regulation by Dsrc41
in developing Drosophila eyes (Takahashi et al.I, 1645-1656
invasion, regulation of tumor cell plasticity by TGF-~ and Ha-Ras (Oft et al.), 2462-2477
regulation by ATM IXu and Balti- more), 2401-2410
migration Breathless role in the Drosophila
tracheal system (Lee et al.), 2912-2921
C-signaling role and traveling wave propagation in Myxococcus (Sager), 2237-2250 Review
cadherins role in intestinal epithe- lium (Hermiston et al.), 985-996
cAMP role and traveling wave prop- agation in Dictyostelium (Sager), 2237-2250 Review
Heartless role in Drosophila devel- opment (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017
polarity, regulation by lin-17 in C. e/- egans (Sawa et al.), 2189-2197
rearrangement, epithelial E-cadherin role in Drosophila (Ue-
mura et al.), 659-671; (Tepass et al.), 672-685
signaling during Drosophila oogenesis (Ray
and Sch~ipbach), 1711-1723 Re- view
in hepatic specification of gut endo- derm (Gualdi et al.), 1670--1682
role of extracellular peptide in differ- ent development pathways in B. subtilis (Solomon et al.), 2014-- 2024
specificity conversion of aNAC to myotube-
specific factor (Yotov and St-Ar- naud), 1763-1772
Pax-5 recruitment of Ets proteins to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211
role of novel bicoid-related homeo box factor Ptxl (Lamonerie et al.), 1284-1295
sequence-specific DNA binding of B-cell POU domain coactivator OCA-B (Cepek et al.), 2079- 2088
tissue-specific inactivation of p53 tu- mor suppression in mice (Bow- man et al.), 826-835
Central nervous system. See Nervous system, central
Geramide-activated protein phos-
3230 GENES & DEVELOPMENT
phatase. See Protein phos- phatase, ceramide-activated
Cerebellum, role of TrkB and TrkC in promoting granule neuron sur- vival (Minichello and Klein), 2849-2858
CF. See Core factor CF2, role in EGF-R-activated dorsoven-
tral patterning (Hsu et al.), 1411-1421
Chaperone proteins, p50 Cdr as protein kinase-targeting subunit of Hsp90 (Stepanova et al.), 1491- 1502
Checkpoints activation by V(D)J recombination in
scid mice (Guidos et al.), 2038- 2054
Bcl-x L and p53 in control (Minn et al.), 2621-2631
cooperativity of p53 and SCID genes in tumorigenesis (Nacht et al.), 2055-2066
cyclin E role in truncation of S phase during the Drosophila endocy- cle {Lilly and Spradling), 2514- 2526
parallel sensory branches for DNA damage signaling in S. cerevi- siae (Navas et al.), 2632-2643
regulation of S-phase onset by fission yeast ORC1 homolog orpl (Grallert and Nurse), 2644-2654
Spkl/Rad53 regulation by Mecl-de- pendent protein phosphoryla- tion (Sun et al.), 395-406
topoisomerases role in chromosome condensation in S. cerevisiae (Castaho et al.), 2564-2576
• preferred selection by RecA protein (Tracy and Kowalczykowski), 1890-1903
Cholesterol metabolism, mediation of SREBP transcriptional activity by CBP (Oliner et al.), 2903- 2911
Chromatin activator-dependent regulation of tran-
scriptional pausing on nucleo- somal templates {Brown et al.), 1479-1490
findings presented at Cold Spring Har- bor meeting (McKnight), 367- 381 Meeting commentary
function of Swp73 in yeast Swi/Snf complex (Cairns et al.), 2131- 2144
identification of mammal ian SWI/ SNF complexes (Wang et al.), 2117-2130
in transcriptional activation and re- pression {Kingston et al.), 905- 920 Review
interaction of Tupl wi th histones H3 and H4 (Edmondson et al.), 1247-1259
NF-KB p50 role in nucleosome arrange- ment of HIV-1 enhancer (Pazin et al.), 37-49
role in hepatic specification of gut en- doderm (Gualdi et al.), 1670- 1682
silent, preferential integration of Ty5 (Zou et al.), 634-645
Chromosome association of Atr and Atm with mei-
otic pairs (Keegan et al.), 2423- 2437
condensation, role of topoisomerases in S. cerevisiae (Castaho et al.), 2564-2576
fragmentation in A TM-deficient mice (Xu et al.), 2411-2422
localization of TFIID and inhibition of activator-dependent transcrip- tion (Segil et al.), 2389-2400
organization dif resolvase site insertions in E. coli
(Kuempel ct al.), 1162-1171; Corrigendum, 1709
:restriction of dif site activity in E. coli (Cornet et al.), 1152-1161
walk, to identify determinants con- trolling activation of yeast rep- lication origins (Friedman et al.), 1595-1607
ci. See cubitus interruptus CIF, role in TFIID-dependent initiator
function (Kaufmann et al.), 873- 886
CIP-1. See p21 CKIs. See Cyclin-dependent kinase in-
hibitors ClbS. See Cyclins Clb6. See Cyclins Cleavage-polyadenylation specificity
factor, interaction with U1 snRNP (Lutz et al.), 325-337
Clnl . See Cyclins Cln2. See Cyclins Cln3. See Cyclins CNS. See Nervous system, central Coactivators, transcriptional
findings presented at Cold Spring Har- bor meeting (McKnight), 367- 381 Meeting commentary
interaction of CBP with (Dai et al.), 528-540
mediation of SREBP transcriptional activity by CBP (Oliner et al.), 2903-2911
role of TFIIA in Ras-mediated photore- ceptor determination (Zeidler et al.), 50-59
sequence-specific DNA binding of B-cell POU domain coactiva- tot OCA-B (Cepek et al.), 2079- 2088
Coconvcrsion, biases accompanying in- tron homing (Mueller et al.), 2158-2166
Cofactors
role of EVES motif in c-Myb regulation (Dash et al.), 1858-1869
transcriptional findings presented at Cold Spring
Harbor meeting (McKnight), 367-381 Meeting commentary
role of CIF in TFIID-dependent ini- tiator function (Kaufmann et al.), 873-886
COL4A3, effects of gene inactivation in mice {Cosgrove et al.), 2981-2992
Collagen, effects of COL4A3 gene inac- t ivation in mice (Cosgrove et al.), 2981-2992
Competence and sporulation stimulat- ing factor, role of extracellular peptide in different develop- ment pathways in B. subtilis {Solomon et al.), 2014-2024
Competence, genetic, role of extracellu- lar peptide in B. subtil is (So- lomon et al.), 2014-2024
Conjugation Atfl regulation by
Spcl in S. pombe (Shiozaki and Rus- sell), 2276-2288
Styl in S. p o m b e {Wilkinson et al.), 2289-2301
conjugating plasmids as preferred tar- gets for Tn7 (Wolkow et al.), 2145-2157
Copper transport, role of yeast protein Ctr3 (Knight et al.), 1917-1929
Core factor, requirement for TBP in UAF-dependent recruitment (Steffan et al.), 2551-2563
Corepressors, role of KAP-1 for KRAB domain {Friedman et al.), 2067- 2078
Corkscrew, analysis of interaction with Torso (Cleghon et al.), 566-577
Corrigenda Gertler et al., 2234 Kuempel et al., 1709
CPP32, similari ty CED-3 substrate spec- ificity (Xue et al.), 1073-1083
CPR. See Recombination, cap-prevented CPSF. See Cleavage-polyadenylation
specificity factor CREB-binding protein
as a coactivator of c-Myb (Dai et al.), 528-540
role in cell differentiation (Eckner et al.),
2478-2490 mediation of SREBP transcriptional
activity (Oliner et al.), 2903- 2911
Crk, phosphorylation of Sin (Alexandro- poulos and Baltimore), 1341- 1355
Crypt-villus, role of cadherins in intesti- nal epithelial cell migration (Hermiston et al.), 985-996
CSF. See Competence and sporulation st imulat ing factor
GENES & DEVELOPMENT 3231
csgA branched C-factor signaling pathway
in Myxococcus (Sogaard-Ander- sen et al.), 740-754
C-signaling and traveling wave propaga- tion in Myxococcus {Sager), 2237-2250 Review
CTD. See RNA polymerase, carboxy-ter- minal domain
CTR3, role of protein product in copper transport in yeast (Knight et al.), 1917-1929
cubitus interruptus activation of patched in response
Hedgehog signaling {Alexandre et al.), 2003-2013
positive regulation of araucan and caupolican (G6mez-Skarmeta and Modolell), 2935-2945
CUS1, role of gene product in spliceo- some assembly {Wells et al.), 220-232
Cyclic AMP regulation of rice blast fungus M.
grisea infection (Xu and Hamer), 2696-2706
traveling wave propagation in Dictyo- stelium (Sager), 2237-2250 Re- view
Cyclin-dependent kinase inhibitors effect of p21 overexpression in trans-
genic mice (Wu et al.), 245-260 role of p21 in keratinocyte growth and
differentiation (Missero et al.), 3065-3075
Ruml inhibition of Cdc2 kinase and interaction with Cdcl8 (Jalle- palli and Kelly), 541-552
vitamin D 3 induction of p21 (Liu et al.), 142-153
Cyclin-dependent kinases activation by Cdc6 during the cell
cylce {Piatti et al.), 1516-1531 cdk2 and cdk3 action in G l (Hofmann
and Livingston), 851-861 Cdk4 as target of Cdc37 in mouse fi-
broblasts (Stepanova et al.), 1491-1502
cell-cycle regulation of SBF binding (Koch et al.), 129-141
regulation of neurite outgrowth by cdk5/p35 kinase (Nikolic et al.), 816-825
role of Xenopus Sucl homolog Xe-p9 in cell cycle control (Patra and Dunphy), 1503-1515
Cyclins cdk-dependent cyclin E ubiquitination
{Clurman et al.), 1979-1990 cell-cycle regulation through SBF
{Koch et al.), 129-141 Clb/Cdc28 in displacing SBF from pro-
moters during G2 (Koch et al.), 129-141
cyclin E requirement for E2F-induced
S phase (Duronio et al.), 2505- 2513
effect of p21 overexpression on cyclin- CDK complex activity (Wu et al.), 245-260
p53-dependent induction of cyclin G (Ko and Prives), 1054-1072 Re- view
role of cyclin E in S phase during the Drosophila endocycle (Lilly and Spradling), 2514-2526
Cyclins, D-type, coexpression of Cdc37 with cyclin D1 in proliferating cells (8tepanova et al.), 1491- 1502
Cysteine proteases role in
apoptosis (White), 1-15 Review cell-death activities in developing C.
elegans neurons (Shaham and Horvitz), 578-591
substrate specificities of CED-3/ICE- like proteases (Xue et al.), 1073- 1083
Cytokinesis, role of dmfl /midl in posi- tioning of division septum in fission yeast {Sohrmann et al.), 2707-2719
Cytoskeleton, role of plectin in mem- brane adherence (McLean et al.), 1724-1735
Danio rerio prospects for insertional mutagenesis
(Schier et al.), 3077-3080 Mini- review
role of pescadillo and dead eye in em- bryonic development (Allende et al.), 3141-3155
dead eye, role in zebrafish development (Allende et al.), 3141-3155
Decapentaplegic positive regulation of araucan and
caupolican {G6mez-Skarmeta and Modolell), 2935-2945
prevention of autoactivation by sog (Biehs et al.}, 2922-2934
decapentaplegic, activation by Cubitus interruptus (Alexandre et al.), 2003-2013
Delta, in Drosophila wing development (Doherty et al.), 421-434
Dentate gyms, role of TrkB and TrkC in promoting neuron survival (Minichello and Klein), 2849- 2858
Development, general cloning of a novel human kinase gene
with homology to Drosophila female sterile homeotic (Denis and Green), 261-271
effects of in vivo mutagenesis of re-
quired HoxD complex regula- tory element (G6rard et al.), 2326-2334
mechanism of hepatic specification of gut endoderm (Gualdi et al.), 1670-1682
Rasl-mediated signaling by PP2A (Wassarman et al.), 272-278
role of Heartless in Drosophila cell migra-
tion and mesodermal lineage development (Beiman et al.), 2993-3002; (Gisselbrecht et al.), 3003-3017
lin-14 3' UTR temporal gradient for- mation in C. elegans (Ha et al.), 3041-3050
pescadillo and dead eye in zebrafish embryogenesis (Allende et al.), 3141-3155
p53 (Ko and Prives), 1054-1072 Re- view
Development, specific. See also Specific organisms
axial, mouse Wnt-3a gene dosage reg- ulation (Greco et al.), 313-324
bone, role of Src-family kinases (Low- ell and Soriano), 1845-1857 Re- view
cartilage, role of p107 and p130 in mice (Cobrinik et al.), 1633- 1644
embryonic requirement for Hlx during mouse
visceral organogenesis (Hentsch et al.), 70-79
role of BMPs {Hogan), 1580-1594 Review
epithelial, role of c-ros (Sonnenberg- Riethmacher et al.), 1184-1193
eye effects on photoreceptor specifica-
tion through regulation of Lozenge role in Drosophila (Daga et
al.), 1194-1205 mouse Pax6 role (Quinn et al.), 435-
446 Rasl regulation of prospero tran-
scription in Drosophila (Kauff- mann et al.), 2167-2178
regulation by Dsrc41 in Drosophila (Takahashi et al.), 1645-1656
TFIIA role in Ras-mediated photore- ceptor determination (Zeidler et al.), 50-59
hair, regulation of inductive tissue in- teractions by Lefl expression (Kratochwil et al.), 1382-1394
immune system, coincident regula- tion of cell cycle and clonality during T-cell receptor develop- ment (Hoffman et al.), 948-962
kidney abnormalities in wild-type p53
transgenic mice (Godley et al.), 836-850
3232 GENES & DEVELOPMENT
regulation by Winged Helix protein BF-2 (Hatini et al.), 1467-1478
role of BMPs (Hogan), 1580-1594 Review
leaf, role of GlossyI5 in maize {Moose and Sisco), 3018-3027
liver, effect of p21 overexpression in transgenic mice (Wu et al.), 245-260
lymphoid, role of Src-family kinases {Lowell and Soriano), 1845- 1857 Review
male, role of FEM-2 phosphatase in C. elegans (Chin-Sang and Spence), 2314-2325
mesodermal, role of C. elegans sere-4 IBasson and Horvitzl, 1953- 1965
nasal, role of mouse Pax6 (Quinn et al.), 435-446
neural opposing cell-death activities in C.
elegans neurons (Shaham and Horvitz), 578-591
regulation of neurite outgrowth by cdkS/p35 kinase (Nikolic et al.), 816-825
role of BMPs (Hogan), 1580-1594 Review Src-family kinases {Lowell and So-
riano), 1845-1857 Review neuronal
role of C. elegans sere-4 (Basson and Horvitz), 1953-1965
role of TrkB and TrkC in promot- ing neuron survival IMinichello and Klein), 2849-2858
postimplantation, abnormalities in BrcaZ-null mice (Liu et al.), 1835-1843
prokaryotic, branched signaling path- way in Myxococcus (Sogaard- Andersen et al.), 740-754
skeletal, role of BMPs {Hogan), 1580- 1594 Review
T-cell, cooperativity of p53 and SCID in lymphomagenesis (Nacht et al.), 2055-2066
tail bud, role of mouse Wnt-3a (Greco et al.), 313-324
tooth regulation of inductive tissue inter-
actions by Lefl expression (Kra- tochwil et al.), 1382-1394
role of BMPs (Hogan), 1580-1594 Review
tracheal, role of Breathless in pattern- ing cell migration and branch- ing in Drosophila (Lee et al.), 2912-2921
vertebrate, induction of patched by hedgehog in mice (Goodrich et al.), 301-312
wing regulation of araucan and caupoli-
can during Drosophila pattern
formation (G6mez-Skarmeta and Modolell), 2935-2945
role of Delta in Drosophila (Doherty et al.), 421-434
Dictyostelium discoideum role of cAMP and traveling wave prop-
agation in morphogenesis (Sager), 2237-2250 Review
signal transduction regulation by ERK2 (Gaskins et al.), 118-128
dif, in Xer site-specific recombination (Blakely and Sherratt), 762-773
dif site restriction of activity in E. coli {Cornet
et al.), 1152-1161 resolvase site insertions in E. coli
(Kuempel et al.), 1162-1171; Corrigendum, 1709
Differentiation adipocyte
role of ADD1/SREBP1 (Kim and Spiegelman), 1096-1107
role of Rb interaction with C/EBPs (Chen et al.), 2794-2804
B-cell, role of p300/CBP and bHLH proteins (Eckner et al.), 2478- 2490
cellular, effects of wild-type p53 trans- gene expression (Godley et al.), 836-850
central nervous system, role of single factors in stem cell differentia- tion (Johe et al.), 3129-3140
differential adipogenic activity of mul- tiple PPAR isoforms (Brunet al.), 974-984
effects of erythropoietin receptor gene inactivation on primitive and definitive erythropoicsis {Lin et al.), 154-164
epithelial regulation by nude locus product
Whn (Brissette-et al.), 2212- 2221
role of c-ros (Sonnenberg-Riethma- cher et al.), 1184-1193
keratinocyte, role of Src-family ki- nases (Lowell and Soriano), 1845-1857 Review
muscle, role of p300/CBP and bHLH proteins (Eckner et al.), 2478- 2490
of myelomonocytes induced by vita- min D 3 (Liu et al.), 142-153
myoblast, role of NAC proteins (Yotov and St-Arnaud), 1763-1772
neuronal regulation of neurite outgrowth by
cdk5/p35 kinase (Nikolic et al.), 816-825
role of Lozenge in Drosophila (Daga et al.), 1194-1205
prokaryotic, branched signaling path- way in Myxococcus {Sogaard- Andersen et al.), 740-754
role of cadherins in intestinal epithe-
lium (Hermiston et al.), 985- 996
role of p53 (Ko and Prives), 1054-1072 Review
sexual, role of MIS in mammalians (Mishina et al.), 2577-2587
skeletal muscle, regulation by Rb (Zackenhaus et al.), 3051- 3064
thymocytes, p53 rescue of V(D)J rear- rangement in scid mice (Bogue et al.), 553-565
DIG1 and DIG2, novel MAP kinase tar- gets in S. cerevisiae (Cook et al.), 2831-2848
dino, role in zebrafish development {Hammerschmidt et al.}, 2452- 2461
dmfl/midl , role in positioning of divi- sion septum in fission yeast {Sohr- mann et al.), 2707-2719
DNA bending, role in transcriptional stimu-
lation by NHP6A/B (Paull et al.), 2769-2781
binding cooperativity of the Oct-1 POU sub-
domains {Klemm and Pabo), 27- 36
sequence specificity of B-cell coacti- vator OCA-B (Cepek et al.), 2079-2088
-binding domains activation of patched by Cubitus in-
terruptus in response Hedgehog signaling (Alexandre et al.), 2003-2013
altered intracellular receptor activa- tion (Starr et al.), 1271-1283
inhibition of ATF-2 transcriptional activation (Li and Green), 517- 527
breaks, double-stranded, activation of DNA damage checkpoint by V(D)I recombination (Guidos et al.), 2038-2054
damage in ATM-deficient mice {Xu et al.),
2411-2422 p53 levels and extent of tumor cell
apoptotic response (Chen et al.), 2438-2451
parallel sensory branches for signal- ing in S. cerevisiae (Navas et al.), 2632-2643
role of p53 in radiation-induced dif- ferentiation in scid mice (Bogue et al.), 553-565
and Spkl/Rad53 regulation by Mecl-dependent protein phos- phorylation (Sun et al.), 395-406
helicases, role of XPB and XPD in p53- dependent apoptosis (Wang et al.), 1219-1232
methylation, role
GENES & DEVELOPMENT 3233
in activation of Xist (Panning and Jaenisch), 1991-2002
in establishing genomic imprinting (Tucker et al.), 1008-1020
of Lon protease in Caulobacter (Wright et al.), 1532-1542
methyltransferase, activity during oo- genesis and spermatogenesis (Tucker et al.), 1008-1020
polymerase ~, parallel sensory branches for signaling in S. cer- evisiae {Navas et al.), 2632- 2643
protein kinase activation of DNA damage check-
point by V(D)J recombination in scid mice (Guidos et al.), 2038- 2054
cooperativity of p53 and SCID genes in tumorigenesis (Nacht et al.), 2055-2066
repair bypass of scid defect by induction of
p53 DNA damage response pathways (Bogue et al.), 553- 565
effects of ATM gene inactiva- tion (Xu and Baltimore), 2401- 2410
encoding of Ku p70 homolog IRBP by Drosophila mus309 (Beall and Rio), 921-933
p53 role (Ko and Prives), 1054-1072 Review
XPB and XPD roles in p53-depen- dent apoptosis (Wang et al.), 1219-1232
replication parallel sensory branches for DNA
damage signaling in S. cerevi- siae (Navas et al.), 2632-2643
promotion by Cdc6 during the cell cycle (Piatti et al.), 1516-1531
regions of yeast RPA subunits with similarity to E. coli SSB pro- tomer (Philipova et al.), 2222- 2233
regulation and specification of eu- karyotic origins (Diffley), 2819- 2830 Review
Spk 1 / Rad53 regulation by Mec 1-de- pendent protein phosphoryla- tion (Sun et al.), 395406
ribosomal, role of TBP in expression in S. cerevisiae (Steffan et al.), 2551-2563
topoisomerases, role in mitotic chro- mosome condensation in S. cer- evisiae (Castafio et al.), 2564- 2576
DNA-PK. See DNA protein kinase Domains, chromosomal, determinants
of late origin activation in yeast (Friedman et al.), 1595-1607
Dominant-negative mutants cdk2 and cdk3 cell cycle function
(Hofmann and Livingston), 851- 861
regulation of neurite outgrowth by cdk5/p35 kinase (Nikolic et al.), 816-825
role of ADD1/SREBP1 in adipocyte differentiation (Kim and 8piegelman), 1096--1107
Dorsal, activation by Toll, tube, and pelle (Norris and Manley), 862-872
Dorsal closure, mediation by Drosophila JNK pathway (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.), 2759-2768
Dorsal-ventral axis, prevention of Dpp autoactivation by Drosophila sog (Biehs et al.), 2922-2934
Double-strand break repair, role in in- tron mobility (Mueller et al.), 351-364
doublesex, assembly of specific SR pro- tein complexes at the splicing enhancer (Lynch and Maniatis), 2089-2101
Drl, corepressor requirement (Mermel- stein et al.), 1033-1048
Drl-associated polypeptide 1, require- ment for Drl-mediated repres- sion (Mermelstein et al.), 1033- 1048
DRAP1. See Drl-associated polypeptide 1
Drosophila activation of dorsal by Toll, tube, and
pelle (Norris and Manley), 862- 872
assembly of specific SR protein com- plexes at the doublesex splicing enhancer (Lynch and Maniatis), 2089-2101
binding of TFIID to downstream basal promoter element (Burke and Kadonaga), 711-724
cloning of a novel human kinase gene with homology to female sterile homeotic (Denis and Green), 261-271
compensatory signaling sites on Torso (Cleghon et al.), 566-577
cyclin E requirement for E2F-induced S phase (Duronio et al.), 2505- 2513
degradation of maternal mRNAs in maternal/zygotic transition (Edgar and Datar), 1966-1977
E-cadherin in epithelial cell rearrange- ment (Uemura et al.), 659-671; (Tepass et al.), 672-685
encoding of bHLH-PAS protein by trachealess
(Wilk et al.), 93-102 Ku p70 homolog IRBP by DNA re-
pair mutant mus309 (Beall and Rio), 921-933
Fab-7 attenuation of enhancer-pro- moter interactions in (Zhou et
al.), 3195-3201 gradual activation of transcription dur-
ing embryogenesis (Pritchard and Schubiger), 1131-1142
independent regulation of neighboring genes (Merli et al.), 1260-1270
induction of S phase and apoptosis by ectopic E2F expression in Drosophila (Asano et al.), 1422- 1432
intercellular signaling and polariza- tion of body axes during oogen- esis {Ray and Sch6pbach), 1711- 1723 Review
JNK pathway mediating morphogene- sis and an immune response (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.), 2759- 2768
posterior patterning by vab-7 (Ahr- inger), 1120-1130
prevention of Dpp autoactivation and suppression of neurogenesis by sog (Biehs et al.), 2922-2934
Rasl regulation of prospero transcrip- tion during eye development (Kauffmann et al.), 2167-2178
RB-related gene RBF (Duet al.), 1206- 1218
regulation of eye development by Dsrc41 (Taka-
hashi et al.), 1645-1656 Rasl-mediated signaling by PP2A
(Wassarman et al.), 272-278 rescue of labial null by chicken or-
tholog Hoxb-1 (Lutz et al.), 176- 184
role of Breathless in patterning cell migra-
tion and branching in the tra- cheal system (Lee et al.), 2912- 2921
CF2 in EGF-R-activated dorsoven- tral patterning (Hsu et al.), 1411-1421
grim in cell death (Chen et al.), 1773-1782
Heartless in cell migration and me- sodermal lineage development (Beiman et al.), 2993-3002; (Gisselbrecht et al.), 3003-3017
Lozenge in eye development (Daga et al.), 1194-1205
plx in tracheal function (Zhang et al.), 1108-1119
porcupine in Wingless processing (Kadowaki et al.), 3116-3128
short-range repressors in regulation of complex loci (Gray and Levine), 700-710
TFIIA during RAS-mediated photo- receptor determination (Zeidler et al.), 50-59
trachealess in embryonic tube for- mation (Isaac and Andrew), 103-117
3234 GENES & DEVELOPMENT
Vein in EGF pathway (Schnepp et al.), 2302-2313
segmentation and specification of me- soderm (Azpiazu et al.), 3183- 3194
translational regulation of nanos mRNA (Dahanukar and Whar- ton), 2610-2620
translational repression of unlocalized nanos mRNA (Smibert et al.), 2600-2609
truncation of S phase during the en- docycle (Lilly and Spradling), 2514-2526
DSBs. See DNA breaks, double-stranded Dsre41, regulation of Drosophila eye
(Takahashi et al.), 1645-1656 Dysplasia, of retinal tissue in p107 null
mice (Lee et al.), 1621-1632
E-box-binding proteins, specificity in gene activation by Myc (Desbar- ats et al.), 447-460
E-cadherin, in Drosophila epithelial cell rearrangement (Uemura et al.), 659-671; (Tepass et al.), 672- 685
E1A, role of p300/CBP and bHLH pro- teins in cell differentiation (Eckner et al.), 2478-2490
E1B 19K protein, functional interaction with Bax (Han et al.), 461-477
E26 leukemia virus, suppression of apo- ptosis by v-Myb (Frampton et al.), 2720-2731
E2F -induced S phase and requirement for
cyclin E (Duronio et al.), 2505- 2513
induction of S phase and apoptosis by ectopic expression in Droso- phila (Asano et al.), 1422-1432
protection of E2F-1 from ubiquitin- proteasome degradation path- way by Rb (Hofmann et al.), 2949-2959
regulation of degradation by Rb family proteins
and adenovirus transforming proteins (Hateboer et al.), 2960- 2970
in Drosophila by Rb-related gene (Du et al.), 1206-1218
E2F-1, DNA binding ability in presence of dominant-negative cdk3 (Hof- mann and Livingston), 851-861
Effective concentration, thermodynamic contribution of the linker in Oct-1 POU domain DNA bind- ing (Klemm and Pabo), 27-36
EGF. See Epidermal growth factor EGF receptor. See Epidermal growth fac-
tor receptor egr-1, induction by PKC-~ overexpres-
sion (Kieser et al.), 1455-1466 EKLF. See Erythroid Krfppel-like factor Elk-l, Pax-5 recruitment to a B-cell-spe-
cific promoter (Fitzsimmons et al.), 2198-2211
Embryogenesis abnormalities in Brcal-null mice (Liu
et al.), 1835-1843 degradation of maternal Cdc25
mRNAs in Drosophila mater- nal/zygotic transition (Edgar and Datar), 1966-1977
effect of dominant-negative Wnt on MyoD induction in Xenopus (Hoppler et al.), 2805-2817
gradual activation of transcription in Drosophila (Pritchard and Schu- biger), 1131-1142
role of BMPs (Hogan), 1580-1594 Review pescadillo and dead eye in zebrafish
(Allende et al.), 3141-3155 signal transduction through ~-cate-
nin (Miller and Moon), 2527- 2539 Review
SL1 RNA in C. elegans (Ferguson et al.), 1543-1556
trachealess in Drosophila (Wilk et al.), 93-102
translational regulation of nanos mRNA (Dahanukar and Whar- ton), 2610-2620
translational repression of unlocalized nanos mRNA (Smibert et al.), 2600-2609
Endocycle, role of cyclin E in truncation of S phase (Lilly and Spradling), 2514-2526
Endoderm, mechanism of hepatic speci- fication in gut development (Gualdi et al.), 1670-1682
Enhancers Fab-7
attenuation of interactions with pro- moter in Drosophila (Zhou et al.), 3195-3201
as chromatin domain boundary in Drosophila (Hagstrom et al.), 3202-3215
in the study of position-effect variega- tion (Wakers et al.), 185-195
Epidermal growth factor, role of Vein in Drosophila signaling pathway (Schnepp et al.), 2302-2313
Epidermal growth factor receptor, role of CF2 in EGF-R-activated dorso- ventral patterning (Hsu et al.), 1411-1421
Epidermis, effects of keratinocyte growth factor gene inactivation (Guo et al.), 165-175
Epidermolysis bullosa, plectin mutation
in MD-EBS in humans (McLean et al.), 1724-1735
Epididymis, role of c-ros in epithelial de- velopment (Sonnenberg-Rieth- reacher et al.), 1184-1193
Epistasis tests, to confirm branched sig- naling pathway in Myxococcus (Sogaard-Andersen et al.), 740- 754
Epithelial-mesenchymal interactions, regulation of inductive tissue interactions by Lefl expression (Kratochwil et al.), 1382-1394
Epithelium intestinal, role of cadherins in cell mi-
gration (Hermiston et al.), 985- 996
mammary, regulation of tumor cell plasticity by TGF-~ and Ha-Ras (Oft et al.}, 2462-2477
nasal, role of mouse Pax6 in develop- ment (Quinn et al.), 435-446
regulation of growth and differentia- tion by nude locus product Whn (Brissette et al.), 2212-2221
role of c-ros in development (Sonnenberg-
Riethmacher et al.), 1184-1193 E-cadherin in development in
Drosophila (Uemura et al.}, 659-671; (Tepass et al.), 672-685
seminiferous, degeneration in RXR~- deficient mice {Kastner et al.), 80--92
EpoR. See Erythropoietin receptor Epstein-Barr virus, transcriptional acti-
vation by ZEBRA protein (Chi and Carey), 2540-2550
ERK, stimulation resulting in phospho- rylation of HSF1 (Knauf et al.), 2782-2793
ERK2, regulation of developmental path- ways in Dictyostelium discoi- deum (Gaskins et al.), 118-128
Errata Lane et at., 365 Goodrich et al., 904 Kaufmann et al., 1296 McGonigle et al., 2235 Polyak et al., 2818
Erythroid Krfippel-like factor, role in human [3-globin gene competi- tion (Wijgerde et al.), 2894- 2902
Erythropoiesis, effects of erythropoietin receptor gene inactivation (Lin et al.), 154-164
Erythropoietin receptor, effects of gene disruption on primitive and de- finitive erythropoiesis (Lin et al.), 154-164
Escherichia coli ~CTD DNA-binding determinants of
RNA polymerase (Gaal et al.), 16-26
GENES & DEVELOPMENT 3235
dif resolvase site insertions (Kuempel et al.), 1162-1171; Corrigen- dum, 1709
HF-1 role in rpoS translation (Muffler et al.), 1143-1151
preferred selection of X recombination hotspot by RecA protein (Tracy a n d Kowalczykowski), 1890- 1903
restriction of dif site activity (Cornet et al.}, 1152-1161
SurA role in outer membrane porin as- sembly (Rouvihre and Gross), 3170-3182
Estl, single-stranded telomere end-bind- ing protein properties (Virta- Pearlman et al.), 3094-3104
Ets family PU.1 ternary complex formation with
Pip (Brass et al.), 2335-2347 recrui tment by Pax-5 to a B-cell-spe-
cific promoter (Fitzsimmons et al.}, 2198-2211
even-skipped, role in segmentation and specification of Drosophila me- soderm (Azpiazu et al.), 3183- 3194
EVES motif, role in regulation of c-Myb (Dash et al.), 1858-1869
Exons coconversion biases accompanying in-
tron homing (Mueller et al.), 2158-2166
role of hrp45 in binding and nucleocy- toplasmic transport of mRNA (Alzhanova-Ericsson et al.), 2881-2893
Exonuclease, 3 ' -~5' , role in 5.85 RNA synthesis {Mitchell et al.), 502- 513
Export, nuclear Npl3p as mediator of RNA export (Lee
et al.), 1233-1246 role of RNA helicase-like protein
HRH1 (Ohno and Shimura), 997-1007
regulation of mRNA export during stress in yeast (Saavedra et al.), 1608-1620
extramacrochaetae, role of Drosophila tamou in activating pathway (Takahisa et al.), 1783-1795
F
Fab-7 at tenuation of enhancer-promoter in-
teractions in Drosophila (Zhou et al.), 3195-3201
as chromatin domain boundary in Drosophila (Hagstrom et al.), 3202-3215
Fat body, role of serpent in Drosophila (Azpiazu et al.), 3183-3194
FEM-2, role in C. elegans sex determina-
tion (Chin-Sang and Spence), 2314-2325
FEM-3, role of interaction with FEM-2 in C. elegans sex determination (Chin-Sang and Spence}, 2314-- 2325
Fertility effect of Bmp8b inactivation in mice
(Zhao et al.), 1657-1669 male, role of c-ros (Sonnenberg-Rieth-
macher et al.), 1184-1193 FGF receptor. See Fibroblast growth fac-
tor receptor Fibroblast growth factor receptor, role of
Drosophila homolog Heartless in cell migration and mesoder- mal lineage development (Be- iman et al.), 2993-3002; (Gissel- brecht et al.), 3003-3017
Fibroblasts, human, p53-dependent cell cycle arrest induced by ribonu- cleotide depletion (Linke et al.), 934-947
Fission yeast. See Yeast, fission fkh. See fork head flp recombinase, to delete enhancers in
the study of position-effect var- iegation (Wakers et al.), 185- 195
Fins, role in p150 ship signal transduction (Lioubin et al.), 1084-1095
Footprinting, genomic, for analysis of cell-cycle regulation of SBF binding (Koch et al.), 129-141
Forebrain, ventral, role of T/EBP in orga- nogenesis (Kimura et al.), 60-69
fork head. control of trachealess expres- sion in the Drosophila salivary duct {Isaac and Andrew), 103- 117
frizzled, similarity of lin- 17 in C. elegans (Sawa et al.), 2189-2197
Fruiting body aggregation, role in C-fac- tor signaling in Myxococcus (Sogaard-Andersen et al.), 740- 754
frz locus, mapping of class I C-factor sig- naling mutat ions in Myxococ- cus (Sogaard-Andersen et al.), 740-754
FrzCd, C-signaling and traveling wave propagation in Myxococcus {Sager), 2237-2250 Review
FtsZ, bipolar localization in B. subtilis (Levin and Losick), 478-488
Go/G ,, p53-dependent cell-cycle arrest induced by ribonucleotide de- pletion (Linke et al.), 934-947
G2, displacement of SBF from promoters during (Koch et al.), 129-141
GADD45, p53-dependent induction (Ko and Prives}, 1054-1072 Review
GAGA factor, role in altering chromatin structure (Kingston et al.), 905- 920 Review
G a l l l P findings presented at Cold Spring Har-
bor meeting (McKnight), 367- 381 Meeting commentary
gene activation by interaction with GAL4 (Farrell et al.), 2359-2367
GAL4, gene activation by interaction with GALl lP (Farrell et al.), 2359-2367
Galactosialidosis, role of mutan t human neuraminidase gene (Bonten et al.), 3156-3169
Gene disruption. See also Gene inactivation
Bmp8b inactivation in mice (Zhao et al.), 1657-1669
EKLF inactivation on [3-globin tran- scription in mice {Wijgerde et al.), 2894-2902
p107 inactivation in mice (Lee et al.), 1621-1632
simultaneous inactivation of p107 and p130 in mice (Cobrinik et al.), 1633-1644
expression activator-dependent regulation of
transcriptional pausing on nu- cleosomal templates (Brown et al.), 1479-1490
differential adipogenic activity of mult iple PPAR isoforms (Brun et al.), 974-984
role of histone amino termini {Ling et al.), 686-699
inactivation. See also Gene disruption ATM disruption in mice {Xu et al.),
2411-2422 Bmp8b disruption in mice (Zhao et
al.), 1657-1669 EKLF disruption on [~-globin tran-
scription in mice (Wijgerde et al.), 2894-2902
erythropoietin receptor (Lin et al.), 154-164
Hlx homeo box gene in mice (Hentsch et al.), 70-79
keratinocyte growth factor (Guo et al.), 165-175
p107 disruption in mice (Lee et al.), 1621-1632
RXR[3 in mice (Kastner et al.), 80-92 simultaneous disruption of p107 and
p130 in mice (Cobrinik et al.), 1633-1644
thyroid-specific enhancer-binding fac- tor in mice (Kimura et al.), 60-69
rearrangement, productive T-cell re- ceptor [3-chain formation (Hoff- man et al.), 948-962
regulation, independent regulation of neighboring genes (Merli et al.), 1260-1270
replacement, targeted, to study inde-
3236 GENES & DEVELOPMENT
pendent regulation of neighbor- ing genes (Merli et al.), 1260- 1270
Genetic imprinting. See Imprinting, ge- netic
Genomic footprinting. See Footprinting, genomic
Genomic stability, role of p53 (Ko and Prives), 1054-1072 Review
Germ cell, male, effect of BmpSb inacti- vation in mice (Zhao et al.), 1657-1669
Germ-line passage, requirement for es- tabl ishment of methylat ion of imprinted genes (Tucker et al.), 1008-1020
GLI family, activation of patched by Cu- bitus interruptus in response Hedgehog signaling (Alexandre et al.), 2003-2013
Globin gene competition, role of EKLF (Wijgerde et al.), 2894-2902
Glossyl5, role in maize leaf develop- ment (Moose and Sisco), 3018- 3027
Glucocorticoid receptor mechanism for interpreting signaling
information {Starr et al.), 1271- 1283
role of Swp73 in transcriptional acti- vation (Cairns et al.), 2131-2144
Glucose, regulation of yeast SNF1 inter- actions (Jiang and Carlson), 3105-3115
Glycogen synthase, regulation of ~-cate- nin by Xgsk-3 (Yost et al.), 1443-1454
Glycoproteins, role of Axl2p in bud-site selection in yeast (Roemer et al.), 777-793
gpdl, induction by Styl and Atfl in S. pombe (Wilkinson et al.), 2289- 2301
GR. See Glucocorticoid receptor Grb2, role of inositol phosphatases in
signal transduction (Majerus), 1051-1053 Minireview
grim, novel cell death gene in Droso- phila (Chen et al.), 1773-1782
Group I introns, as mobile genetic ele- ments (Mueller et al.), 351-364
Growth arrest, genetic determinants of p53 in-
duction (Polyak et al.), 1945- 1952; Erratum, 2818
cones, regulation of neurite outgrowth by cdkS/p35 kinase (Nikolic et al.), 816--825
factors, role of single factors in CNS stem-cell differentiation {Johe et al.), 3129-3140
inhibition, resulting from p21 eleva- tion by C/EBP~ (Timchenko et al.), 804-815
GT sequences, selection as preferred DNA pairing sequences by E.
coli RecA protein (Tracy and Kowalczykowski), 1890-1903
Gut, hypoplasia in mice deficient for HIx (Hentsch et al.), 70-79
H
HI9, role of DNA methylat ion in regu- lating expression (Tucker et al.), 1008-1020
Hair, effects of keratinocyte growth fac- tor gene inactivation (Guo et al.), 165-175
Heart role of Heartless in Drosophila devel-
opment (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017
specification in Drosophila (Azpiazu et al.), 3183-3194
Heartless, role in Drosophila cell migra- tion and mesodermal lineage development (Beiman et al.), 2993-3002; (Gisselbrecht et al.), 3003-3017
Heat shock effect on subcellular localization of
poly(A) + RNA in yeast (Saave- dra et al.), 1608-1620
factors regulation of HSF1 by phosphoryla-
tion (Knauf et al.), 2782-2793 role in activation of metal lothionein
by oxidative stress (Liu and Thiele), 592-603
use of HSF1 activation domain to readthrough transcriptional paus- ing (Brown et al.), 1479-1490
genes activator-dependent release of tran-
scriptional pausing on the hsp70 gene {Brown et al.), 1479- 1490
findings presented at Cold Spring Harbor meeting (McKnight), 367-381 Meeting commentary
ribosome jumping in treated cells (Yueh and Schneider), 1557- 1567
hedgehog, role in segmentation and specification of Drosophila me- soderm (Azpiazu et al.), 3183- 3194
Hedgehog family
PKA as a negative regulator (Ham- merschmidt et al.), 647-658
role of signaling in activation of patched by cubitus interruptus (Alexandre et al.), 2003-2013
signaling induction of patched in mice (Goo-
drich et al.}, 301-312 positive regulation of araucan and
caupolican by Ci (G6mez-
Skarmeta and Modolell), 2935- 2945
Helicase, role of RNA helicase-like pro- tein HRH1 in nuclear export (Ohno and Shimura), 997-1007
Hel ix- loop-hel ix proteins, basic bHLH-PAS protein as inducer of
Drosophila tracheal cell fates (Wilk et al.), 93-102
role of ADD1/SREBP1 in adipocyte dif-
ferentiation (Kim and Spiegel- man), 1096-1107
in cell differentiation Eckner et al.), 2478-2490
Helix-loop--helix/leucine zipper pro- teins, specificity m gene activa- tion by Myc (Desbarats et al.), 447-460
Hematopoeisis, impairment in mice de- ficient for Hlx (Hentsch et al.), 70-79
Hematopoietic cells, activation of JNK/ SAPK pathway by HPK1 (Hu et al.), 2251-2264
Hematopoietic progenitor kinase 1, acti- vation of JNK/SAPK pathway (Hu et al.), 2251-2264
Hepatocytes, cell-cycle arrest from p21 overexpression in transgenic mice (Wu et al.), 245-260
Heterochromatin, role of silencers in in- heritance of repression in yeast (Holmes and Broach), 1021- 1032
High mobil i ty group proteins, transcrip- tional s t imulat ion by NHP6A/B (Paull et al.), 2769-2781
Hippocampus, role of TrkB and TrkC in promoting neuron survival (Minichello and Klein), 2849- 2858
Histone mRNA, SLBP as novel RNA- binding protein required for pro- cessing (Wang et al.), 3028-3040
Histones role of amino termini in nucleosome
assembly (Ling et al.), 686-699 Swel regulator interaction with H3
and H4 amino termini (Ma et al.), 1327-1340
Tupl interaction with H3 and H4 (Ed- mondson et al.), 1247-1259
HIV. See Human immunodeficiency vi- rus
HLH/LZ proteins. See Helix-loop-he- l ix/ leucine zipper proteins
hnRNPs. See Ribonucleoproteins HO, role of Swp73 in expression (Cairns
et al.), 2131-2144 Holoenzyme
gene activation by GAL4--GAL11P in- teraction (Farrell et al.), 2359- 2367
role in Pol II transcription (Orphanides et al.), 2657-2683 Review
GENES & DEVELOPMENT 3237
Homeo box genes Hlx is essential for expansion of
mouse embryonic liver and gut (Hentsch et al.), 70-79
novel bicoid-related homeo box factor Ptxl (Lamonerie et al.), 1284-- 1295
posterior patterning by vab-7 (Ahr- inger), 1120-1130
regulation of araucan and caupolican during Drosophila wing devel- opment (G6mez-Skarmeta and Modolell), 2935-2945
HOM-C genes, rescue of Drosophila la- bial null by chicken ortholog Hoxb-1 (Lutz et al.), 176--184
Hox genes in vivo mutagenesis of required HoxD
complex regulatory element (G4rard et al.), 2326-2334
rescue of Drosophila labial null by chicken ortholog Hoxb-I (Lutz et al.), 176-184
Hoxb-1, chicken, rescue of Drosophila labial null (Lutz et al.), 176-184
HoxD complex, in vivo mutagenesis of required regulatory element (G4rard et al.), 2326--2334
HPK1. See Hematopoietic progenitor ki- nase 1
HPR1, role of protein product in yeast telomeric size control (Li and Lustig), 1310-1326
HRH1, role in nuclear export (Ohno and Shimura), 997-1007
HSF. See Heat shock factors HSF1, regulation by phosphorylation
(Knauf et al.), 2782-2793 HSL1, interaction of protein product
with histone amino termini (Ma et al.), 1327-1340
HSL7, interaction of protein product with histone amino termini (Ma et al.), 1327-1340
Hsp70 gene family hsp70 activator-dependent release of
transcriptional pausing (Brown et al.), 1479-1490
nucleocytoplasmic export of SSA4 mRNA during stress in yeast (Saavedra et al.), 1608-1620
Hsp90, p50 Cdr as protein kinase-target- ing subunit (Stepanova et al.), 1491-1502
Human immunodeficiency virus, chro- matin reconfiguration and tran- scriptional activation of the HIV-1 enhancer by NF-KB (Pa- zin et al.), 37-49
ICE-related cysteine proteases induction by BID, a novel death ago-
nist possessing only a BH3 do-
main (Wang et al.), 2859-2869 role in
apoptosis (White), 1-15 Review cell-death activities in developing C.
elegans neurons (Shaham and Horvitz), 578-591
substrate specificities (Xue et al.), 1073-1083
IGF-BP3, as transcriptional target of p53 (Ko and Prives), 1054-1072 Re- view
Igf2, role of DNA methylation in regu- lating gene expression (Tucker et al.), 1008-1020
Igf2r, role of DNA methylation in regu- lating gene expression (Tucker et al.), 1008-1020
Immune response, mediation by Drosophila JNK pathway (Sluss et al.), 2745-2758
Immune system coincident regulation of cell cycle and
clonality during T-cell receptor development (Hoffman et al.), 948-962
defects in ATM-deficient mice (Xu et al.), 2411-2422
role of ATM (Hawley and Friend), 2383-2388 Review
Immunofluorescence microscopy, to study localization of FtsZ in B. subtilis (Levin and Losick), 478- 488
Immunoglobulin production, role of Pip ternary complex formation with PU.1 (Brass et al.), 2335-2347
Imprinting, genetic, role of DNA meth- ylation (Tucker et al.), 1008- 1020
Imprinting, genomic, role of DNA meth- ylation (Tucker et al.), 1008-1020
Induction of egr-1 by PKC-~ overexpression
(Kieser et al.), 1455-1466 of junB by PKC-~ overexpression
(Kieser et al.), 1455-1466 of metanephric mesenchyme differen-
tiation by Winged Helix protein BF-2 (Hatini et al.}, 1467-1478
IFN. See Interferon Initiator element, role
binding of Drosophila TFIID to down- stream basal promoter element (Burke and Kadonaga), 711-724
CIF as cofactor for TFIID-dependent function [Kaufmann et al.), 873- 886
Inositol polyphosphate 5-phosphatases p150 ship and Fms signal transduction
{Lioubin et al.), 1084-1095 role in signal transduction (Majerus),
1051-1053 Minireview Inositols
inositol polyphosphate 5-phosphatases (Majerus), 1051-1053 Minire- view
p150 ship and Fms signal transduction (Lioubin et al.), 1084-1095
Inr. See Initiator element Insertional mutagenesis. See Mutagene-
sis, insertional Insulators, Fab-7
attenuation of enhancer-promoter in- teractions in Drosophila (Zhou et al.), 3195-3201
as chromatin domain boundary in Drosophila (Hagstrom et al.), 3202-3215
Integration, transposon targeting of retrotransposon Tyl to up-
stream regions of RNA pol II- transcribed genes (Devine and Boeke), 620-633
of Ty5 into regions of silent chromatin (Zou et al.), 634-645
Intercellular signaling, cAMP and travel- ing wave propagation in Dicty- ostelium (Sager), 2237-2250 Re- view
Interferon effect on expression of PML and POD
reorganization (Doucas et al.), 196-207
regulatory factor family, Pip autoinhi- bition and ternary complex for- mation with PU.1 (Brass et al.), 2335-2347
Intestines, role of cadherins in epithelial cell migration (Hermiston et al.), 985-996
Intracellular receptor family, common mechanism for interpreting sig- naling information at response elements [Starr et al.), 1271- 1283
Intracellular transduction, cAMP and traveling wave propagation in Dictyostelium (Sager), 2237- 2250 Review
Intron enhancer, role in activation of polya-
denylation {Lou et al.), 208-219 exon coconversion biases accompany-
ing homing (Mueller et al.), 2158-2166
homing, pathways in T4 phage (Muel- let et al.), 351-364
Inverted repeat-binding protein, as Drosophila homolog of Ku p70 (Beall and Rio), 921-933
IP5Pases. See Inositol polyphosphate 5-phosphatases
IR family. See Intracellular receptor fam- ily
IRBP. See Inverted repeat-binding pro- tein
IRF family. See Interferon regulatory fac- tor family
islet [~ cells, rise and fall of apoptosis dur- ing multistage tumorigenesis (Naik et al.), 2105-2116
Isomerase, peptidyl-prolyl, role of SurA
3238 GENES & DEVELOPMENT
in protein folding in E. coli (Rouvi6re and Gross), 3170- 3182
Isomerase, prolyl, mammalian RAFT1 as target of FKBPl2-rapamycin (Alarcon et al.1, 279-288
JNKs. See c-Jun amino-terminal kinases junB, induction by PKC-~ overexpres-
sion (Kieser et al.), 1455-1466
K
KAP-1, identification as KRAB domain corepressor (Friedman et al.), 2067-2078
Keratinocyte growth factor, effects of gene inactivation (Guo et al.), 165-175
Keratinocytes p21 role in growth and differentiation
(Missero et al.), 3065-3075 regulation of epithelial growth and dif-
ferentiation by nude locus prod- uct Whn (Brissette et al.), 2212- 2221
Src-family kinases role in differentia- tion (Lowell and Soriano), 1845- 1857 Review
KGF. See Keratinocyte growth factor Kidney, COL4A3-deficient mice as
model for Alport syndrome (Cosgrove et al.), 2981-2992
Kinase suppressor of Ras, role in MAPK signaling pathway (Therrien et al.), 2684-2695
Kinases Atr- and Atm-associated activity (Kee-
gan et al.), 2423-2437 characterization of a novel nuclear ki-
nase in human cells (Denis and Green), 261-271
Digl and Dig2 as substrates of Kssl in S. cerevisiae (Cook et al.), 2831- 2848
function of human TOR homolog RAFT1 (Alarcon et al.), 279-288
glucose regulation of yeast SNF1 com- plex interactions (Jiang and Carlson), 3105-3115
interaction of Swel regulators with histone amino termini (Ma et al.), 1327-1340
regulation of Atfl by Styl in S. pombe (Wilkinson
et al.), 2289-2301 [3-catenin by Xgsk-3 (Yost et al.),
1443-1454 role of Xenopus Sucl homolog Xe-p9
in cell cycle control (Patra and Dunphy), 1503-1515
serine, role in stress response signaling
in B. subtilis (Yang et al.), 2265- 2275
Spkl/Rad53 regulation by Mecl-de- pendent protein phosphoryla- tion (Sun et al.), 395-406
Src-family, effects of gene disruptions in mice (Lowell and Soriano), 1845-1857 Review
tyrosine, regulation of Drosophila eye development by Dsrc41 (Taka- hashi et al.), 1645-1656
Kluyveromyces lactis, role of cap-pre- vented recombination in telom- ere maintenance (McEachern and Blackburn), 1822-1834
KRAB domain. See Krfippel-associated box domain
Krfippel, as transcriptional repressor (Gray and Levine), 700-710
Kr/ippel-associated box domain, identifi- cation of KAP-1 as corepressor (Friedman et al.), 2067-2078
KSR. See Kinase suppressor of Ras Ku, encoding of p70 homolog IRBP by
Drosophila mus309 Beall and Rio), 921-933
L
labial, rescue of gene inactivation in Drosophila by chicken ortholog Hoxb-1 (Lutz et al.), 176-184
LCR. See Locus control region Lefl, regulation of inductive tissue inter-
actions (Kratochwil et al.), 1382-1394
Lens, role of mouse Pax6 in eye develop- ment (Quinn et al.), 435-446
Leucine zipper proteins basic
cloning of Atfl and Atf21 in S. pombe (8hiozaki and Russell), 2276-2288
regulation of Atfl by Styl in S. pombe (Wilkinson et al.), 2289- 2301
role of ADD1/SREBP1 in adipocyte differentiation (Kim and Spiegelman), 1096-1107
Leukemia elevation of a novel nuclear kinase in
acute and chronic lymphocytic (Denis and Green), 261-271
suppression of myeloid cell apoptosis by E26 v-Myb (Frampton et al.), 2720-2731
LIM motifs, two interacting surfaces of (Arber and Caroni), 289-300
LIM proteins, specificity of LIM-based interactions (Arber and Caroni), 289--300
Limb buds, role of BMPs in patterning (Hogan), 1580-1594 Review
lin-4, role of duplex formation with lin- 14 in down-regulation of trans-
lation (Ha et al.), 3041-3050 lin-14, role of 3' UTR in down-regulation
of translation (Ha et al.), 3041- 3050
lin-17, role in asymmetric cell division in C. elegans (Sawa et al.), 2189-2197
LIN-44, LIN-17 as receptor for asymmet- ric cell division in C. elegans (Sawa et al.), 2189-2197
Lineage analysis, posterior patterning by vab-7 (Ahringer), 1120-1130
Lipid metabolism, in Sertoli cells of RXR[3-deficient mice (Kastner et al.), 80-92
Liver accelerated apoptosis in plO7-null
mice (Lee et al.), 1621-1632 hypoplasia in mice deficient for Hlx
(Hentsch et al.), 70-79 mechanism of hepatic specification of
gut endoderm (Gualdi et al.), 1670-1682
regeneration, effect of p21 overexpres- sion in transgenic mice (Wu et al.), 245-260
Localization nuclear
colocalization of APETALA3 and PISTILLATA (McGonigle et al.), 1812-1821
of Madr2 in response to activin (Baker and Harland), 1880-1889
subcellular anticodon as signal sequence for
tRNA import into mitochon- dria (Rusconi and Cech), 2870- 2880
of TFIID and inhibition of activator- dependent transcription (Segil et al.), 2389-2400
translational regulation of nanos mRNA (Dahanukar and Whar- ton), 2610-2620
translational repression of unlocalized nanos mRNA (Smibert et al.), 2600-2609
Locus control region, role of EKLF in hu- man [3-globin gene competition (Wijgerde et al.), 2894-2902
Lon protease, role of in cell-cycle control of DNA methylation (Wright et al.), 1532-1542
Lozenge, role in Drosophila eye develop- ment (Daga et al.), 1194-1205
Lung, role of T/EBP in organogenesis (Kimura et al.), 60-69
Lymphocytes activation of DNA damage checkpoint
by V(D)J recombination in scid mice (Guidos et al.), 2038-2054
effects of ATM disruption in mice (Xu et al.), 2411-2422
role of ATM (Hawley and Friend), 2383-2388 Review
Lymphoma
GENES & DEVELOPMENT 3239
in ATM-deficient mice (Xu et al.), 2411-2422
role of ATM (Hawley and Friend), 2383-2388 Review
Lymphomagenesis, cooperativity of p53 and SCID genes (Nacht et al.), 2055-2066
Lysosome, identification of human neur- aminidase gene and role in sial- idosis (Bonten et al.), 3156-3169
M
Madr2, participation in the activin signal transduction pathway (Baker and Harland), 1880-1889
Magnaporthe grisea, MAP kinase and cAMP regulation of infection (Xu and Hamer), 2696-2706
MAGUK proteins. See Membrane-asso- ciated guanylate kinase proteins
Maize, role of Glossyl5 in leaf develop- ment (Moose and Sisco), 3018- 3027
MAP kinase pathway DIGI and DIG2 as two novel targets
in S. cerevisiae (Cook et al.), 2831-2848
Drosophila JNK pathway mediating morphogenesis and an immune response (Sluss et al.), 2745- 2758; {Riesgo-Escovar et al.), 2759-2768
inhibition of JNK/SAPK activation by HPK1 (Hu et al.), 2251-2264
Rasl regulation of prospero transcrip- tion during Drosophila eye de- velopment (Kauffmann et al.), 2167-2178
regulation of Atfl by Spcl in S. pombe (Shiozaki
and Russell), 2276-2288 Atfl by Styl in S. pombe (Wilkinson
et al.), 2289-2301 developmental pathways by ERK2
in Dictyostelium discoideum {Gaskins et al.), 118-128
rice blast fungus M. grisea infection (Xu and Hamer), 2696-2706
role of KSR (Therrien et al.), 2684- 2695
stimulation of Raf/ERK resulting in phosphorylation of HSF 1 (Knauf et al.), 2782-2793
MAP4. See Microtubule-associated pro- tein
Maternal/zygotic transition, role of deg- radation of maternal Cdc25 mRNAs (Edgar and Datar), 1966-1977
Mating-type locus effects of telomere proximity and Sir
protein concentration on silenc- ing {Maillet et al.), 1796-1811
role of
Rapl protein in silencing (Marcand et al.), 1297-1309
silencers in inheritance of repres- sion in yeast (Holmes and Broach), 1021-1032
Max, role in specific gene activation by Myc {Desbarats et al.), 447-460
rob-1 promoter, Pax-5 recruitment of Ets proteins (Fitzsimmons et al.), 2198-2211
MD-EBS. See Muscular dystrophy; see also Epidermolysis bullosa
mdm-2, as transcriptional target of p53 {Ko and Prives), 1054-1072 Re- view
Mdx, and MyoD in muscle regeneration (Megeney et al.), 1173-1183
Mecl, regulation of Spkl/Rad53 (Sun et al.), 395-406
Mec2, regulation by Mecl-dependent protein phosphorylation {Sun et al.), 395-406
Meioisis association with paired chromosomes
(Keegan et al.), 2423-2437 effects of ATM disruption in mice (Xu
et al.), 2411-2422 regulation by Spcl through Atfl tran-
scription in S. pombe {Shiozaki and Russell), 2276-2288
role of ATM in recombination (Haw- ley and Friend), 2383-2388 Re- view
MEK, effects of KSR cooperation with Ras (Therrien et al.), 2684-2695
Membrane-associated guanylate kinase proteins, identification of Drosophila ZO-1 homolog ta- mou (Takahisa et al.), 1783- 1795
Menadione, strong activation of yeast CUP1 (Liu and Thiele), 592-603
Mesenchyme, stromal, essential role in kidney morphogenesis (Hatini et al.}, 1467-1478
Mesoderm effect of dominant-negative Wnt on
development in Xenopus em- bryos (Hoppler et al.), 2805- 2817
paraxial, role of mouse Wnt-3a in for- mation (Greco et al.), 313-324
role of C. elegans sem-4 in development
(Basson and Horvitz), 1953- 1965
Heartless in Drosophila develop- ment (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017
Madr2 in induction (Baker and Hat- land), 1880-1889
segmentation and specification in Drosophila (Azpiazu et al.), 3183-3194
Messenger RNA
increase in polyadenylation efficiency (Lutz et al.), 325-337
precursors effects of U1 snRNA on 5' splice site
selection (Hwang and Cohen), 338-350
nuclear cap-binding complex role in recognition and splicing (Lewis et al.), 1683-1698
redundant interactions between U2 and U6 snRNAs during splicing (Field and Friesen), 489-501
SLBP role in processing histone pre- mRNA (Wang et al.), 3028-3040
U2AF 35-kD subunit role in splicing (Zuo and Maniatis), 1356-1368
RNA helicase-like protein HRH1 role in nuclear export (Ohno and Shimura), 997-1007
translational repression of unlocalized nanos mRNA (Smibert et al.), 2600-2609
U2AF 35-kD subunit role in splicing (Zuo and Maniatis), 1356-1368
Metal response elements, use of the met- allothionein enhancer to study position-effect variegation (Wai- ters et al.), 185-195
Metal-binding proteins, activation of metallothionein by oxidative stress via HSF (Liu and Thiele), 592-603
Metallothionein activation by oxidative stress via HSF
{Liu and Thiele), 592-603 enhancer, in the study of position-ef-
fect variegation (Walters et al.), 185-195
Metanephros, induction of differentia- tion by Winged Helix protein BF-2 (Hatini et al.), 1467-1478
Methylation activation of Xist by DNA hypometh-
ylation (Panning and Jaenisch), 1991-2002
role of Lon protease in Caulobacter (Wright et al.), 1532-1542
Methyltransferase activity during oogenesis and sper-
matogenesis (Tucker et al.), 1008-1020
CcrM as target of Lon protease in Cau- lobacter (Wright et al.), 1532- 1542
Microtubule -associated protein, negative regula-
tion of MAP4 expression by p53 (Murphy et al.), 2971-2980
negative regulation of MAP4 expres- sion by p53 (Murphy et al.), 2971-2980
Migration, neuronal, effects of Tst-1/ Oct-6/SCIP deletion in mice {Bermingham et al.), 1751-1762
MIS. See Mfillerian-inhibiting substance Mismatch repair
3240 GENES & DEVELOPMENT
eukaryotic, biochemistry and genetics (Kolodner), 1433-1442 Review
prokaryotic, similarities of eukaryotic pathways (Kolodner), 1433- 1442 Review
redundancy of MSH3 and MSH6 (Mar- sischky et al.), 407--420
Mitochondria, anticodon as signal se- quence for tRNA import (Rusconi and Cech), 2870-2880
Mitosis Bcl-x L and p53 in checkpoint control
(Minn et al.), 2621-2631 inhibit ion of activator-dependent tran-
scription (Segil et al.), 2389- 2400
role of topoisomerases in chromosome condensation in S. cerevisiae (Castaho et al.), 2564-2576
MLP, LIM-mediated interaction with the actin cytoskeleton (Arber and Caroni), 289-300
MMTV. See Mouse mammary tumor vi- rus
Morphogenesis branching, role of Breathless in Droso-
phila (Lee et al.), 2912-2921 C-signaling and traveling wave propa-
gation in Myxococcus (Sager), 2237-2250 Review
cAMP and and traveling wave propa- gation in Dictyostelium (Sager), 2237-2250 Review
cell, role of Axl2p in bud site selection in yeast (Roemer et al.), 777- 793
egg cylinder, failure in Brcal-null mice (Liu et al.), 1835-1843
epithelial, role of E-cadherin in Droso- phila (Uemura et al.), 659-671; {Tepass et al.), 672-685
mediation by Drosophila JNK path- way (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.), 2759- 2768
prevention of Dpp autoactivation and suppression of neurogenesis by Drosophila sog (Biehs et al.), 2922-2934
Mouse mammary tumor virus, rear- rangement of Notchl in mouse thymomas in transgenic mice (Girard et al.), 1930-1944
MREs. See Metal response elements mRNA. See Messenger RNA MSH2, role in mismatch repair and re-
dundancy of MSH3 and MSH6 (Marsischky et al.), 407-420
MSH3, redundancy with MSH6 in MSH2-dependent mismatch re- pair (Marsischky et al.), 407- 420
MSH6, redundancy with MSH3 in MSH2-dependent mismatch re- pair (Marsischky et al.), 407- 420
M611erian-inhibiting substance, role in mammalian sexual differentia- tion (Mishina et al.), 2577-2587
MUD13, identification of protein prod- uct as yeast homolog of CBP20 (Color et al.), 1699-1708
Multiprotein complexes, LIM motifs as specific adaptor elements (Arber and Caroni), 289-300
Muscle cells, role of p300/CBP and bHLH pro-
teins in differentiation (Eckner et al.), 2478-2490
effect of dominant-negative Wnt on development in Xenopus em- bryos (Hoppler et al.), 2805- 2817
regeneration, role of MyoD in myo- genic stem cell function (Megeney et al.), 1173-1183
role of Heartless in Drosophila devel- opment (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017
skeletal regulation of development by Rb
(Zackenhaus et al.), 3051-3064 role of MyoD in myogenic stem cell
function (Megeney et al.), 1173- 1183
Muscular dystrophy plectin mutat ion in MD-EBS in hu-
mans (McLean et al.), 1724- 1735
role of MyoD in myogenic stem cell function (Megeney et al.), 1173- 1183
Musculature, visceral, role of bagpipe in Drosophila (Azpiazu et al.), 3183-3194
Mutagen sensitivity, encoding of Ku p70 homolog IRBP by Drosophila mus309 (Beall and Rio), 921- 933
Mutagenesis insertional
identification of pescadillo and dead eye in zebrafish (Allende et al.), 3141-3155
prospects for use in zebrafish (Schier et al.), 3077-3080 Minireview
redundancy of MSH3 and MSH6 in MSH2-dependent mismatch re- pair (Marsischky et al.), 407- 420
MutHLS, comparison of E. coli and eu- karyotic mismatch repair path- ways (Kolodner), 1433-1442 Re- view
MutL proteins, eukaryotic homologs (Kolodner), 1433-1442 Review
MutS proteins, eukaryotic homologs (Kolodner), 1433-1442 Review
Myb. See also c-Myb CBP as coactivator (Dai et al.), 528-540 regulation of bcl-2 by dominant inter-
fering form (Taylor et al.), 2732- 2744
suppression of apoptosis by E26 v-Myb (Frampton et al.), 2720-2731
Myc. See also c-myc specificity in gene activation (Desbar-
ats et al.), 447-460 Myelination, peripheral, regulation by
Tst-1/Oct-6/SCIP in mice (Ber- mingham et al.), 1751-1762
Myeloid cells regulation of bcl-2 by dominant inter-
fering Myb (Taylor et al.), 2732- 2744
role of Src-family kinases in develop- ment (Lowell and Soriano), 1845-1857 Review
suppression of apoptosis by E26 v-Myb (Frampton et al.), 2720-2731
Myelomonocytes, vi tamin D 3 and in- duced differentiation of U937 cells (Liu et al.), 142-153
MyoD induction blocked by dominant-nega-
tive Wnt in Xenopus embryos (Hoppler et al.), 2805-2817
role in myogenic stem cell function (Megeney et al.), 1173-1183
Myogenesis Heartless role in Drosophila develop-
ment (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017
p300/CBP and bHLH proteins roles in muscle cell differentiation (Eck- ner et al.), 2478-2490
regulation of skeletal muscle cell dif- ferentiation by Rb (Zackenhaus et al.), 3051-3064
Myoglobin, putative skNAC binding sites in promoter (Yotov and St- Arnaud), 1763-1772
Myxococcus xanthus branched C-factor signaling pathway
in (Sogaard-Andersen et al.), 740-754
C-signaling and traveling wave propa- gation (Sager), 2237-2250 Re- view
MZT. See Maternal /zygotic transition
N
NAC. See Nascent polypeptide-associ- ated complex
nanos, repression of unlocalized mRNA translation by smaug (Smibert et al.), 2600-2609
Nascent polypeptide-associated com- plex, conversion of ~NAC to myotube-specific factor (Yotov and St-Arnaud), 1763-1772
Nematodes. See also Caenorhabditis el- egans
in vitro transposition of Tcl in C. ele- gans (Vos et al.), 755-761
GENES & DEVELOPMENT 3241
opposing cell-death activities in devel- oping neurons (Shaham and Horvitz), 578-591
Nephron, regulation of development by Winged Helix protein BF-2 (Ha- tini et al.), 1467-1478
Nervous system, central accelerated apoptosis in p107 null
mice (Lee et al.), 1621-1632 plx role in tracheal function (Zhang et
al.), 1108-1119 single factors role in stem cell differ-
entiation (Johe et al.), 3129- 3140
Net, Pax-5 recruitment to a B-cell-spe- cific promoter (Fitzsimmons et al.), 2198-2211
Neuraminidase, identification of human gene and role in sialidosis (Bon- ten et al.), 3156-3169
Neuregulin, similarity of Drosophila Vein (Schnepp et al.), 2302-2313
Neurite outgrowth, regulation cdk5/p35 kinase (Nikolic et al.), 816-825
Neurodegeneration, modulation by in- teractions between wild-type and mutant prion proteins in mice (Telling et al.), 1736-1750
Neuroectoderm role of E-cadherin in development in
Drosophila (Tepass et al.), 672- 685
suppression of neurogenesis by Droso- phila sog (Biehs et al.), 2922- 2934
Neurogenesis coupling of cell lineage asymmetry
with unc-86 transcription (Bau- meister et al.), 1395-1410
suppression by Drosophila sog (Biehs et al.), 2922-2934
Neurons role of C. elegans sere-4 in develop-
ment (Basson and Horvitz), 1953-1965
role of TrkB and TrkC in promoting survival (Minichello and Klein), 2849-2858
Neurotrophins, role of TrkB and TrkC in promoting neuron survival (Mini- chello and Klein), 2849-2858
NF-KB. See also rel/NFKB proteins induction by TANK (Cheng and Balti-
more), 963-973 -mediated chromatin reconfiguration
and transcriptional activation of HIV-1 enhancer (Pazin et al.), 37-49
NHP6A/B. See Nonhistone proteins 6A and 6B
Nodal, asymmetric expression in verte- brate embryo (Hogan), 1580- 1594 Review
Nonhistone proteins 6A and 6B, role in transcriptional stimulation in S. cerevisiae (Paull et al.), 2769-2781
Notch, role of ligand Delta in Drosophila wing development (Doherty et al.), 421-434
Notchl, rearrangement in mouse T-cell lymphoma (Girard et al.), 1930- 1944
NPL3, role of protein product in RNA export in yeast (Lee et al.), 1233-1246
Nuclear division, role of topoisomerases in chromosome condensation in S. cerevisiae (Castaho et al.), 2564-2576
Nuclear export. See Export, nuclear Nuclear hormone receptors, differential
adipogenic activity of multiple PPAR isoforms (Brune t al.), 974-984
Nuclear organization, POD organization and adenoreplication (Doucas et al.), 196-207
Nuclear pore, role of hrp45 in nucleocy- toplasmic transport of mRNAs (Alzhanova-Ericsson et al.), 2881-2893
Nuclear receptors. See Receptors, nu- clear
Nucleases, competition in coconversion biases accompanying intron hom- ing (Mueller et al.), 2158-2166
Nucleocytoplasmic ratio, role in gradual activation of transcription in Drosophila (Pritchard and Schu- biger), 1131-1142
Nucleocytoplasmic transport, role of hrp45 in accompanying pre- mRNA to nuclear pores (Alzha- nova-Ericsson et al.), 2881-2893
Nucleosomes in chromatin structure (Kingston et
al.), 905-920 Review role
of histone amino termini in assem- bly (Ling et al), 686-699
in transcriptional pausing (Brown et al.), 1479-1490
Nude mouse, regulation of epithelial growth and differentiation by nude locus product Whn (Bris- sette et al.), 2212-2221
NURF, role in altering chromatin struc- ture (Kingston et al.), 905-920 Review
Nutrients, stimulation of Tap42 associ- ation with PP2A (DiComo and Amdt), 1904-1916
O
OCA-B, sequence-specific DNA binding (Cepek et al.), 2079-2088
Oct-1 POU domain-DNA interactions
(Klemm and Pabo), 27-36 sequence-specific DNA binding of
B-cell POU domain coactivator OCA-B (Cepek et al.), 2079- 2O88
Oct-2, sequence-specific DNA binding of B-cell POU domain coactivator OCA-B (Cepek et al.), 2079- 2088
Oct-6, effects of gene deletion in mice (Bermingham et al.), 1751-1762
Olfactory tract, effects of Tst-1/Oct-6/ SCIP deletion in mice (Berming- ham et al.), 1751-1762
Oncogenesis, collaboration of c-myc with Notchl in MMTV/myc transgenic mice (Girard et al.), 1930-1944
Oocyte determination, role of cyclin E in S phase during the Drosophila endocycle (Lilly and Spradling), 2514--2526
Oogenesis CF2 role in EGF-R-activated dorsoven-
tral patterning (Hsu et al.), 1411-1421
defects in ATM-deficient mice (Xu et al.), 2411-2422
intercellular signaling and polariza- tion of body axes in Drosophila (Ray and Schiipbach), 1711- 1723 Review
Oskar protein-protein interactions in Drosophila pole plasm forma- tion (Breitwieser et al.), 2179- 2188
ORC regulation of S-phase onset by fission yeast ORC1
homolog orpl (Grallert and Nurse), 2644-2654
and specification of eukaryotic replica- tion origins (Diffley), 2819- 2830 Review
Organogenesis BMPs {Hogan), 1580-1594 Review Hlx in mice (Hentsch et al.), 70-79 pescadillo and dead eye in zebrafish
(Allende et al.), 3141-3155 T/EBP in mice (Kimura et al.), 60-69
Organs, sensory regulation of araucan and caupolican
during Drosophila wing pat- terning (G6mez-Skarmeta and Modolell), 2935-2945
role of Drosophila tamou in formation (Takahisa et al.), 1783-1795
Origins, replication determinants of late activation (Fried-
man et al.), 1595-1607 regulation and specification of eukary-
otic origins (Diffley), 2819-2830 Review
orpl, regulation of S-phase onset in fis- sion yeast (Grallert and Nurse), 2644-2654
orthodenticle, novel related homeo box factor Ptxl (Lamonerie et al.), 1284-1295
3242 GENES & DEVELOPMENT
Oskar, role of protein-protein interac- tions in Drosophila pole plasm formation (Breitwieser et al.), 2179-2188
Osmotic regulation, role of HF-I in E. coli (Muffler et al.J, 1143-1151
OSS1, interaction of protein product with histone amino termini (Ma et al.), 1327-1340
Otx-1, novel related homeo box factor Ptxl (Lamonerie et al.), 1284- 1295
Otx-2, novel related homeo box factor Ptxl (Lamonerie et al.), 1284- 1295
Outer membrane porins, role of SurA in assembly in E. coli (Rouvihre and Gross), 3170-3182
Oxidative stress, activation of metal- lothionein via HSF (Liu and Thiele), 592-603
P
P element disruption of trachealess in Droso-
phila (Isaac and Andrew), 103- 117
severe reduction of excision in mus309 mutants (Beall and Rio), 921-933
p21 elevation by C/EBP~ and inhibition of
cell proliferation (Timchenko et al.), 804-815
overexpression in transgenic mice (Wu et al.), 245-260
as p53 response gene IKo and Prives), 1054-1072 Review
role in ATM function {Xu and Baltimore),
2401-2410 keratinocyte growth and differentia-
tion (Missero et al.), 3065-3075 p53-dependent cell-cycle arrest in-
duced by ribonucleotide deple- tion (Linke et al.), 934-947
p53-dependent tumor cell apoptotic response {Chen et al.), 2438- 2451
p53-induced growth arrest (Polyak et al.), 1945-1952; Erratum, 2818
vitamin D 3 induction of (Liu et al.), 142-153
p53 abnormal kidney development in
transgenic mice (Godley et al.), 836-850
activation of DNA damage checkpoint by V(D)J recombination (Guidos et al.), 2038-2054
cooperativity with SCID defect in tu- morigenesis (Nacht et al.), 2055-2066
current advances (Ko and Prives), 1054-1072 Review
-dependent cell-cycle arrest induced by ribonucleotide depletion (Linke et al.), 934-947
functional interaction of E1B 19K with Bax (Han et al.), 461-477
genetic determinants of growth arrest versus apoptosis (Polyak et al.), 1945-1952; Erratum, 2818
levels and extent of tumor cell apop- totic response (Chen et al.), 2438-2451
negative regulation of MAP4 expres- sion (Murphy et al.), 2971-2980
rise and fall of apoptosis during multi- stage tumorigenesis (Naik et al.), 2105-2116
role in apoptosis (White), 1-15 Review ATM function (Hawley and Friend),
2383-2388 Review; (Xu and Bal- timore), 2401-2410
mitotic checkpoint control (Minn et al.), 2621-2631
radiation-induced differentiation and rescue of V(D)J rearrange- ment in scid mice (Bogue et al.), 553-565
role of XPB and XPD in apoptosis (Wang et al.), 1219-1232
tissue-specific inactivation of tumor suppression in mice (Bowman et al.), 826-835
p107 effect of targeted disruption in mice
(Lee et al.), 1621-1632 shared role of protein product with
p130 in limb development in mice tCobrinik et al.), 1633- 1644
p130, shared role of protein product with p107 in limb d~velopment in mice (Cobrinik et al.), 1633- 1644
p130 c~, role of related protein Sin in c-Src activation (Alexandropou- los and Baltimore), 1341-1355
pl50Ship
Fms signal transduction (Lioubin et al.), 1084-1095
role of inositol phosphatases in signal transduction (Majerus), 1051- 1053 Minireview
p300 interaction with SREBP (Oliner et al.),
2903-2911 role in cell differentiation (Eckner et
al.), 2478-2490 p35 kinase. See cdk5 p50 Cdc37, protein kinase-targeting sub-
unit of Hsp90 (Stepanova et al.), 1491-1502
PAS proteins, bHLH-PAS protein as in- ducer of Drosophila tracheal cell fates (Wilk et al.), 93-102
patched activation by Gubitus interruptus in
response Hedgehog signaling (Alexandre et al.), 2003-2013
induction by hedgehog in mice (Good- rich et al.), 301-312
Pattern formation posterior patterning by vab-7 (Ahr-
inger), 1120-1130 regulation of araucan and caupolican
during Drosophila wing pat- terning (G6mez-Skarmeta and Modolell), 2935-2945
rescue of Drosophila labial null by chicken ortholog Hoxb-1 (Lutz et al.), 176-184
role of CF2 in EGF-R-activated Drosophila
dorsoventral patterning (Hsu et al.), 1411-1421
Drosophila Lozenge (Daga et al.), 1194-1205
Patterning dorsoventral
CF2 role in EGF-R-activated dorso- ventral patterning (Hsu et al.), 1411-1421
dino and swirl roles in zebrafish (Hammerschmidt et al.), 2452- 2461
embryonic, polarization of body axes during Drosophila oogenesis (Ray and Sch~ipbach), 1711- 1723 Review
role of BMPs (Hogan), 1580-1594 Re- view
wing, role of Delta in Drosophila (Doherty et al.), 421--434
Pax genes, role of Pax6 in mouse devel- opment (Quinn et al.), 435--446
Pax-5, recruitment of Ets proteins to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211
Pax6, role in mouse development (Quinn et al.), 435--446
Pdslp, control of anaphase initiation in S. cerevisiae by APC-dependent degradation (Cohen-Fix et al.), 3081-3093
pelle kinase, functional interactions with Toll receptor and tube (Norris and Manley), 862-872
Periplasm, role of SurA in protein folding in E. coli {Rouvihre and Gross), 3170-3182
Peroxisome proliferation-activated re- ceptor, differential adipogenic activity of multiple isoforms (Brunet al.), 974-984
pescadillo, role in zebrafish develop- ment (Allende et al.), 3141- 3155
PEV. See Position-effect variegation Phage T4, exon coconversion biases ac-
companying intron homing (Mueller et al.), 2158-2166
GENES & DEVELOPMENT 3243
Phosphatases ceramide-activated mediates G1 arrest
in Saccharomyces cerevisiae (Nickels and Broach), 382-394
FEM-2 role in C. elegans sex determi- nation (Chin-Sang and Spence), 231 4-2325
inositol phosphatases role in signal transduction (Majerus), 1051- 1053 Minireview
nutrient stimulation of Tap42 associ- ation with PP2A (DiComo and Arndt), 1904-1916
p 1 $0 ship and Fms signal transduction (Lioubin et al.), 1084-1095
serine, role in stress response signaling in B. subtilis (Yang et al.), 2265- 2275
SpoIIE in Bacillus subtilis (Feucht et al.}, 794-803
Phosphorylation analysis of key residues for Torso sig-
naling (Cleghon et al.), 566- 577
Digl and Dig2 as substrates of Kssl in S. cerevisiae (Cook et al.), 2831- 2848
regulation of B-catenin by Xgsk-3 (Yost et al.),
1443-1454 HSF1 (Knauf et al.}, 2782-2793
role in activation of dorsal by Toll, tube and
pelle (Norris and Manley), 862- 872
cdk-dependent cyclin E ubiquitina- tion (Clurman et al.), 1979- 1990
role of FEM-2 phosphatase in C. e/e- gans sex determination (Chin- Sang and Spence), 2314-2325
of Spkl/Rad53 as regulated by Mecl (Sun et al.), 395-406
SpoIIE as phosphatase in Bacillus sub- tills (Feucht et al.}, 794-803
of SR proteins (Manley and Tacke), 1569-1579 Review
of TFIID and inhibition of activator- dependent transcription (Segil et al.}, 2389-2400
Photoreceptor cells effects on specification through regu-
lation of Rasl-mediated signal- ing by PP2A (Wassarman et al.), 272-278
role of Drosophila Lozenge in cell-fate determination (Daga et al.), 1194-1205
Phyllopod, role in upregulation of pros- pero transcription during Drosophila eye development (Kauffmann et al.), 2167-2178
Pip, autoinhibition and ternary complex formation with PU.1 (Brass et al.), 2335-2347
PISTILLATA, nuclear colocalization
with APETALA3 (McGonigle et al.), 1812-1821
Pituitary abnormalities in Rb +/- mice (Nikitin
and Leel, 1870-1879 expression of bicoid-related homeo
box factor Ptxl (Lamonerie et al.}, 1284--1295
role of T/EBP in organogenesis (Kimura et al.), 60-69
PKA. See Protein kinase A PKI, in Hedgehog signaling as dominant-
negative form of PKA (Hammer- schmidt et al.), 647-658
Plant pathogens, MAP kinase and cAMP regulation of rice blast fungus M. grisea infection (Xu and Hamer), 2696-2706
Plasma membrane proteins, role of Axl2p in bud-site selection in yeast (Roemer et al.), 777- 793
Plasmids, conjugating, as preferred tar- gets for Tn7 (Wolkow et al.), 2145-2157
Plasticity, phenotypic, regulation by TGF-~ and Ha-Ras (Oft et al.), 2462-2477
Plectin, loss and epidermolysis bullosa with muscular dystrophy (McLean et al.), 1724-1735
PMKI, role in rice blast fungus M. grisea infection (Xu and Hamer), 2696-2706
PML. See Promyelocytic leukemia nu- clear protein
POD. See Promyelocytic leukemia onco- genic domain
Polar granules, role of Oskar protein- protein interactions in assem- bly (Breitwieser et al.), 2179- 2188
Polarity, cell, role of Axl2p in bud-site selection in yeast (Roemer et al.), 777-793
Pole plasm, role of Oskar interaction with Vasa in formation (Breitwieser et al.), 2179-2188
pollux, role in tracheal function (Zhang et al.), 1108-1119
Poly(A) + RNA effect of stress on subcellular localiza-
tion in yeast (Saavedra et al.), 1608-1620
nuclear accumulation in Npl3p tem- perature-sensitive mutants (Lee et al.}, 1233-1246
Polyadenylation effects of CPSF interaction with the
U1 snRNP-A protein (Lutz et al.), 325-337
splice-site containing poly(A) en- hancer (Lou et al.), 208-219
Polycomb genes, role in transcriptional repression (Kingston et al.), 905-920 Review
Polyomavirus, role of Src-family kinases in tumorigenesis (Lowell and Soriano), 1845-1857 Review
Polypyrimidine tract-binding protein, in- hibition of polyadenylation cleavage (Lou et al.), 208-219
POMC gene. See Pro-opiomelanocortin gene
porcupine, encoding of putative trans- membrane protein involved in Wingless processing (Kadowaki et al.), 3116-3128
Porins, role of SurA in outer membrane assembly in E. coli (Rouvi6re and Gross), 3170-3182
Position effect, telomeric effect on transcriptional silencing
(Maillet et al.), 1796-1811 role of Rapl protein (Marcand et al.),
1297-1309 Position-effect variegation, suppression
by transcriptional enhancers (Wakers et al.), 185-195
Potentiator, mutation in GALl 1 that al- lows GAL4 interaction (Farrell et al.), 2359-2367
POU domain proteins cooperative binding of Oct-1 POU sub-
domains {Klemm and Pabo), 27- 36
coupling of cell lineage asymmetry with unc-86 transcription (Bau- meister et al.), 1395-1410
effects of Tst-1/Oct-6/SCIP deletion in mice (Bermingham et al.), 1751-1762
sequence-specific DNA binding of B-cell coactivator OCA-B (Ce- pek et al.), 2079-2088
PP2A. See Protein phosphatase type 2A PP2C. See Protein phosphatase type 2C PPAR. See Peroxisome proliferation-ac-
tivated receptor PPCA. See Protective protein/cathepsin A pre-mRNA. See Messenger RNA, precur-
sors Pre-RCs. See Prereplicative complexes Preinitiation complex
NHP6A/B role in assembly in S. cere- visiae (Paull et al.), 2769-2781
UAF role in formation (Keys et al.), 887-903
Prereplicative complexes assembly at eukaryotic replication or-
igins (Diffley), 2819-2830 Re- view
promotion by Cdc6 during the cell cy- cle (Piatti et al.), 1516-1531
Prions de novo generation of infectivity (Tell-
ing et al.), 1736-1750 role of human Prp homolog HRH1 in
nuclear export (Ohno and Shimura), 997-1007
Programmed cell death. See also Apop- tosis
3244 GENES & DEVELOPMENT
Bcl-x L and p53 in checkpoint control (Minn et al.), 2621-2631
BID as novel death agonist possessing only a BH3 domain (Wang et al.), 2859-2869
functional interaction of E1B 19K with Bax (Han et al.), 461-477
grim role in Drosophila (Chen et al.}, 1773-1782
opposing cell-death activities in C. el- egans neurons (Shaham and Horvitz), 578-591
p53 levels and extent of tumor cell ap- optotic response (Chen et al.), 2438-2451
regulators and pathways (White), 1-15 Review
substrate specificities of CED-3/ICE- like proteases (Xue et al.), 1073- 1083
suppression by E26 v-Myb (Frampton et al.), 2720-2731
XPB and XPD role in p53-dependent pathway (Wang et al.), 1219- 1232
Proliferation, cellular effects of erythropoietin receptor gene
inactivation (L ine t al.), 154- 164
inhibition through p21 elevation by C/EBPa (Timchenko et al.), 804-815
role of ATM in regulation (Xu and Bal- timore), 2401-2410
Prolyl isomerases. See Isomerase, prolyl
Promoter binding of Drosophila TFIID to down-
stream basal element (Burke and Kadonaga), 711-724
codirection of TFIIIB binding to tRNA genes by TBP and TFIIIC (Joazeiro et al.), 725-739
RNA polymerase ~ subunit binding in E. coli (Gaal et al.), 16-26
specificity, independent regulation of neighboring genes (Merli et al.), 1260-1270
Promoter/enhancer interaction, inde- pendent regulation of neighbor- ing genes (Merli et al.), 1260- 1270
Promyelocytic leukemia nuclear protein, and adenovirus repli-
cation (Doucas et al.), 196-- 207
oncogenic domain, and adenovirus replication Doucas et al.), 196- 207
Pro-opiomelanocortin gene, transcrip- tional regulation by Ptxl (Lam- onerie et al.), 1284-1295
prospero, Rasl regulation during Droso- phila eye development {Kauff- mann et al.), 2167-2178
Proteases, role of Lon protease in cell-
cycle control of DNA methyl- ation (Wright et al.), 1532- 1542
Proteasome protection of E2F-1 from degradation
pathway by Rb (Hofmann et al.), 2949-2959
regulation of cyclin E turnover by cdk2 (Clurman
et al.), 1979-1990 E2F degradation by Rb family pro-
teins and adenovirus transform- ing proteins (Hateboer et al.), 2960-2970
Protective protein/cathepsin A, interac- tion with human neuramini- dase (Bonten et al.), 3156- 3169
Protein degradation
APC-dependent proteolysis of Pdslp (Cohen-Fix et al.), 3081-3093
protection of E2F-1 from ubiquitin- proteasome degradation path- way by Rb (Hofmann et al.), 2949-2959
regulation of E2F degradation by Rb family proteins and adenovirus transforming proteins (Hateboer et al.), 2960-2970
folding, role of SurA in E. cob (Rou- vihre and Gross), 3170-3182
import, inhibition following cellular stress in yeast (Saavedra et al.), 1608-1620
Protein kinase A, as a negative regulator of Hedgehog signaling (Ham- merschmidt et al.), 647-658
Protein kinase C, suppression of v-raf transformation by PKC-~ (Kieser et al.), 1455-1466
Protein kinases. See Kinases Protein kinases, stress activated
activation by HPK1 (Hu et al.), 2251- 2264
regulation of Atfl by Styl in S. pombe (Wilkinson et al.), 2289-2301
Protein phosphatase, ceramide-activated mediation of G~ arrest in Saccharomy-
ces cerevisiae (Nickels and Broach), 382-394
Protein phosphatase type 2A nutrient stimulation of Tap42 associ-
ation with PP2A (DiComo and Arndt), 1904-1916
regulation of Rasl-mediated signaling (Wassarman et al.), 272-278
Protein phosphatase type 2C, role of FEM-2 in C. elegans sex de- termination (Chin-Sang and Spence), 2314-2325
Protein phosphatases. See Phosphatases Protein stabilization, extension of p21
half-life by C/EBPa (Tim- chenko et al.), 804-815
Protein synthesis, ribosome jumping in
virus-infected and heat-shocked cells (Yueh and Schneider), 1557-1567
Protein-DNA interactions, cooperativi- ty of the Oct-1 POU subdo- mains (Klemm and Pabo), 27- 36
Protein-protein interactions Digl and Dig2 as substrates of Kssl in
S. cerevisiae (Cook et al.), 2831- 2848
FEM-2 and FEM-3 in C. elegans sex de- termination (Chin-Sang and Spence), 2314-2325
function of the U2AF 35-kD subunit (Zuo and Maniatis), 1356-1368
glucose regulation of yeast SNF1 com- plex interactions (Jiang and Carlson), 3105-3115
mediation of SREBP transcriptional activity by CBP (Oliner et al.), 2903-2911
with Oskar in Drosophila pole plasm formation (Breitwieser et al.), 2179-2188
Pax-5 recruitment of Ets proteins to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211
PU.1 ternary complex formation with Pip (Brass et al.), 2335-2347
role of EVES motif in c-Myb regulation
(Dash et al.), 1858-1869 Rb interaction with C/EBPs in adi-
pocyte terminal differentiation (Chen et al.), 2794-2804
Sin in c-Src activation (Alexandropou- los and Baltimore), 1341-1355
specificity of LIM-LIM interactions (Arber and Caroni), 289-,300
SpoIIAB with CF in B. subtilis (Decatur and Losick), 2348-2358
stimulation of phosphatase activity in B. subtilis (Yang et al.), 2265- 2275
Proteins, tissue-specific conversion of aNAC to myotube-spe-
cific factor (Yotov and St-Ar- naud), 1763-1772
sequence-specific DNA binding of B-cell POU domain coactivator OCA-B (Cepek et al.), 2079- 2088
Prothymosin-a gene, specific activation by Myc (Desbarats et al.), 447-460
PrP genes. See Prions PTB. See Polypyrimidine tract binding
protein Ptxl, novel bicoid-related homeo box
factor (Lamonerie et al.), 1284- 1295
PU.1, ternary complex formation with Pip (Brass et al.), 2335-2347
pyp2, induction by Sty1 and Atfl in S. pombe (Wilkinson et al.), 2289- 2301
GENES & DEVELOPMENT 3245
r7 photoreceptor. See also Photoreceptor cells
RAD9, parallel sensory branches for DNA damage signaling in S. cerevisiae (Navas et al.), 2632- 2643
RAD52, role of protein product homolog in RAD51-independent recom- bination in yeast (Bai and Sym- ington), 2025-2037
Rad53, regulation by Mecl-dependent protein phosphorylation (Sun et al.), 395--406
Radiation, ionizing, role of p53 in radia- tion-induced differentiation in scid mice (Bogue et al.), 553- 565
Raf comparison of KSR (Therrien et al.),
2684-2695 effect of PP2A on signaling (Wassar-
man et al.), 272-278 stimulation resulting in phosphoryla-
tion of HSF1 (Knauf et al.), 2782-2793
RAFT1 kinase domain, rapamycin-sensi- tive TOR function in yeast (Alarcon et al.), 279-288
RAG proteins. See Recombinase activat- ing gene proteins
Ran/TC4 GTPase system, role in regula- tion of mRNA during stress in yeast (Saavedra et al.), 1608- 1620
Rap l protein, role in silencing at non- telomeric regions (Marcand et al.), 1297-1309
Rapamycin sensitivity role of Tot signaling in nutrient stim-
ulation of Tap42 association with PP2A (DiComo and Arndt), 1904-1916
TOR function in yeast (Alarcon et al.), 279-288
Rapid deletion, telomeric, novel mecha- nism for telomere size control in yeast (Li and Lustig), 1310- 1326
Ras aggressive tumorigenic behavior of
p21-deficient keratinocytes af- ter transformation (Missero et al.), 3065-3075
cooperation with TGF-[~ in regulation of tumor cell plasticity (Oft et al.), 2462-2477
cooperativity with KSR (Therrien et al.), 2684-2695
effect of PP2A on signaling (Wassar- man et al.), 272-278
Rasl regulation of prospero transcrip- tion during Drosophila eye de- velopment (Kauffmann et al.), 2167-2178
role of TFIIA in photoreceptor deter- mination (Zeidler et al.), 50-59
Rasl signaling and transcription during development (Kauffmann et al.), 2167-2178
Ras pathway, Lozenge interaction to de- termine photoreceptor cell (Daga et al.), 1194-1205
Rb dephosphorylation during p53-depen-
dent cell cycle arrest induced by ribonucleotide depletion (Linke et al.), 934-947
differential effects of cdk2 and cdk3 on E2F function during G~ exit (Hofmann and Livingston), 851- 861
functional overlap of p107 in mice (Lee et al.), 1621-1632
protection of E2F-1 from ubiquitin- proteasome degradation path- way (Hofmann et al.), 2949- 2959
regulation of E2F degradation (Hateboer et al.l,
2960-2970 skeletal muscle-cell development in
mice (Zackenhaus et al.), 3051- 3064
related Drosophila gene RBF (Due t al.), 1206-1218
role in apoptosis (White), 1-15 Review of interaction with C/EBPs in adipo-
cyte terminal differentiation (Chen et al.), 2794-2804
Rb family regulation of E2F degradation by p107
and p130 (Hateboer et al.), 2960-2970
shared role of p107 and p130 in limb development in mice (Cobrinik et al.), 1633-1644
RBF, Drosophila Rb-related gene (Duet al.), 1206-1218
rDNA. See DNA, ribosomal RecA protein, preferred DNA pairing se-
quences (Tracy and Kowal- czykowski), 1890-1903
Receptor tyrosine kinases Breathless role in patterning cell mi-
gration and branching in Droso- phila (Lee et al.), 2912-2921
c-ros role in epithelial development (Sonnenberg-Riethmacher et al.), 1184-1193
compensatory signaling sites on Torso (Cleghon et al.), 566-577
Heartless role in Drosophila develop- ment (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017
regulation of Rasl-mediated signaling by PP2A in Sevenless pathway (Wassarman et al.), 272-278
TrkB and TrkC role in promoting neu-
ton survival (Minichello and Klein), 2849-2858
Vein role in Drosophila EGF pathway (Schnepp et al.), 2302-2313
Receptors, nuclear, in vivo mutagenesis of required HoxD complex reg- ulatory element (G6rard et al.), 2326-2334
Recombinase activating gene proteins
activation of DNA damage check- point by V(D)J recombination (Guidos et al.), 2038-2054
role of RAG2 in T-cell receptor [3-chain gene rearrangement (Hoffman et al.), 948-962
in Xer site-specific recombination (Blakely and Sherratt), 762-773
Recombination cap-prevented, role in telomere main-
tenance (McEachern and Black- burn), 1822-1834
exon coconversion biases accompany- ing intron homing (Mueller et al.), 2158-2166
meiotic effects of ATM disruption in mice
(Xu et al.), 2411-2422 role of ATM (Hawley and Friend),
2383-2388 Review role in telomere maintenance
(McEachern and Blackburn), 1822-1834
role of Rad52 homolog in RAD51-in- dependent process in yeast {Bai and Symington), 2025-2037
selection of preferred DNA pairing se- quences by E. coli RecA protein (Tracy and Kowalczykowski), 1890-1903
site-specific determinants of Xer selectivity
(Blakely and Sherratt), 762-773 restriction of dif site activity in E.
coli (Cornet et al.), 1152-1161 V(D)!
activation of p53-dependent DNA damage checkpoint (Guidos et al.), 2038-2054
requirement of p53 for rescue in scid mice (Bogue et al.), 553-565
Regionalization, role of c-ros in epitheli- al development (Sonnenberg- Riethmacher et al.), 1184-1193
Regulation, negative, role of EVES motif in c-Myb regulation (Dash et al.), 1858-1869
rel/NFKB proteins activation of dorsal by Toll, tube, and
pelle (Norris and Manley), 862- 872
NFKB-mediated chromatin reconfigu- ration and transcriptional acti- vation of HIV- 1 enhancer (Pazin et al.), 37-49
Replication. See also DNA replication
3246 GENES & DEVELOPMENT
conjugating plasmids as preferred tar- gets for Tn7 {Wolkow et al.), 2145-2157
determinants of late origin activation {Friedman et al.), 1595-1607
overexpression of Ruml and re-repli- cation in fission yeast (Jallepalli and Kelly), 541-552
parallel sensory branches for DNA damage signaling in S. cerevi- siae (Navas et al.), 2632-2643
POD organization and adenoreplica- tion (Doucas et al.), 196-207
promotion by Cdc6 during the cell cy- cle (Piatti et al.), 1516-1531
recombination-dependent, as a path- way for intron mobility (Muel- let et al.), 351-364
regions of yeast RPA subunits with similarity to E. coli SSB pro- tomer (Philipova et al.), 2222- 2233
regulation and specification of eukary- otic origins (Diffley), 2819-2830 Review
Replication protein A, yeast domains with similarity to the E. coli SSB protomer (Philipova et al.), 2222-2233
Replicon model, of eukaryotic replica- tion (Diffley), 2819-2830 Re- view
Repressed state, role of silencers in in- heritance (Holmes and Broach), 1021-1032
Repression, transcriptional altered intracellular receptor activa-
tion properties (Start et al.), 1271-1283
CF2 role in EGF-R-activated dorsoven- tral patterning (Hsu et al.), 1411-1421
corepressor requirement for Drl (Mer- melstein et al.), 1033-1048
effects of telomere proximity and Sir protein concentration on silenc- ing (Maillet et al.), 1796-1811
identification of KAP-1 as KRAB do- main corepressor (Friedman et al.), 2067-2078
interaction of Tupl with histones H3 and H4 (Edmondson et al.), 1247-1259
short-range repressors role in Droso- phila embryos (Gray and Levine), 700-710
silencers role in yeast {Holmes and Broach), 1021-1032
Repressor, maternal, titration of during Drosophila embryogenesis (Pritchard and Schubiger), 1131-1142
Resolvase, dif site insertions in E. coli (Kuempel et al.), 1162-1171; Corrigendum, 1709
Respiration, effects of Tst-1/Oct-6/SCIP
deletion in mice {Bermingham et al.), 1751-1762
Retina, dysplasia in p107-null mice (Lee et al.), 1621-1632
Retrotransposons integration of Ty5 into regions of si-
lent chromatin (Zou et al.), 634- 645
targeting of Tyl to upstream regions of RNA pol III-transcribed genes (Devine and Boeke), 620--633
Retroviruses, frequent provirus inser- tional mutagenesis in MMTV/ myc transgenic mice {Girard et al.), 1930-1944
Ribonucleoproteins, role of hrp45 in binding to exonic pre-mRNA and nucleocytoplasmic trans- port {Alzhanova-Ericsson et al.), 2881-2893
Ribosomal DNA. See DNA, ribosomal Ribosomal RNA. See RNA, ribosomal Ribosome jumping, in virus-infected and
heat shocked cells (Yueh and Schneider), 1557-1567
Ribosome shunting. See Ribosome jumping
Rice blast fungus, MAP kinase and cAMP regulation of M. grisea infection (Xu and Hamer), 2696-2706
RING finger proteins, identification of KAP-1 as KRAB domain core- pressor (Friedman et al.), 2067- 2078
RING3, a novel nuclear kinase in human cells (Denis and Green), 261-271
RNA -binding proteins
HF-I role in rpoS translation (Muff- ler et al.), 1143-1151
SLBP role in processing histone pre-mRNA (Wang et al.), 3028- 3040
bulged, role in down-regulation of LIN-14 (Ha et al.), 3041-3050
export hrp45 role in accompanying pre-
mRNA to nuclear pores (Alzha- nova-Ericsson et al.), 2881-2893
Npl3p as mediator (Lee et al.), 1233- 1246
regulation during stress in yeast (Saavedra et al.), 1608-1620
RNA helicase-like protein HRH1 role (Ohno and Shimura), 997- 1007
helicase, role of RNA helicase-like protein HRH1 in nuclear export (Ohno and Shimura), 997-1007
import, anticodon as signal sequence for targeting tRNA to mito- chondria (Rusconi and Cech), 2870-2880
localization, anticodon as signal se-
quence for tRNA import into mitochondria (Rusconi and Cech), 2870--2880
polymerase carboxy-terminal domain, NMR
analysis of novel DNA-binding domain (Gaal et al.), 16-26
DNA-binding determinants of the {~ subunit in E. coli (Gaal et al.), 16-26
findings presented at Cold Spring Harbor meeting (McKnight), 367-381 Meeting commentary
gene activation by Pol II holoen- zyme recruitment (Farrell et al.), 2359-2367
Pol II general transcription factors (Orphanides et al.), 2657-2683 Review
role of TBP in Pol I transcription of rDNA in S. cerevisiae (Steffan et al.), 2551-2563
role of UAF in pol I preinitiation complex formation (Keys et al.), 887-903
targeting of Tyl integration to up- stream regions of pol III-tran- scribed genes (Devine and Boeke), 620-633
processing SL1 RNA role in C. elegans embryo-
genesis (Ferguson et al.), 1543- 1556
3'--~5' exonuclease role in 5.8S RNA synthesis {Mitchell et al.), 502-513
ribosomal SL1 RNA role in C. elegans embryo-
genesis (Ferguson et al.), 1543- 1556
3'---~5' exonuclease role in 5.8S RNA synthesis {Mitchell et al.), 502-513
RNA-protein interactions, role of the U2AF 35-kD subunit (Zuo and Maniatis), 1356-1368
RNPs. See Ribonucleoproteins RPA. See Replication protein A RRN5, role of protein product in RNA
pol I preinitiation complex for- mation {Keys et al.), 887-903
RRN9, role of protein product in RNA pol I preinitiation complex for- mation {Keys et al.), 887-903
RRNIO, role of protein product in RNA pol I preinitiation complex for- mation (Keys et al.), 887-903
rRNA. See RNA, ribosomal RRP4 gene, role of protein product in
5.8S RNA synthesis {Mitchell et al.), 502-513
RS domains, role in splicing (Manley and Tacke), 1569-1579 Review
Ruml, inhibition of Cdc2 kinase and in- teraction with Cdcl8 (Jallepalli and Kelly), 541-552
GENES & DEVELOPMENT 3247
Runt, homologous domains found in Lozenge (Daga et al.), 1194- 1205
RXRB, effects of gene inactivation in mice (Kastner et al.), 80-92
S phase determinants of late origin activation
in yeast (Friedman et al.), 1595- 1607
regulation of onset by fission yeast ORC1 homolog orpl (Grallert and Nurse), 2644-2654
role of E2F and cyclin E in Drosophila (Duronio et al.), 2505-2513
timing of replication promotion by Cdc6 during the cell cycle (Pi- atti et al.), 1516-1531
truncation during the Drosophila en- docycle (Lilly and Spradling), 2514-2526
Saccharomyces cerevisiae. See also Yeast, budding
activation of CUP1 in strains lacking SOD1 (Liu and Thiele), 592-603
APC-dependent degradation of Pdslp (Cohen-Fix et al.), 3081-3093
ceramide-activated protein phos- phatase (Nickels and Broach), 382-394
CUS1 gene product role in spliceo- some assembly (Wells et al.), 220-232
determinants of late origin activation (Friedman et al.), 1595-1607
DIG1 and DIG2 as two novel MAP ki- nase targets (Cook et al.), 2831- 2848
epigenetic effects on transcription caused by mutations in a nu- clear actin-related protein (Jiang and Stillman), 604-619
function of human TOR homolog RAFT1 (Alarcon et al.), 279-288
function of Swp73 in Swi/Snf complex (Cairns et al.), 2131-2144
glucose regulation of SNF1 complex interactions (Jiang and Carlson), 3105-3115
histone amino-termini role in nucleo- some assembly (Ling et al.), 686-699
identification of Mudl3p as homolog of CBP20 (Color et al.), 1699- 1708
in vivo function of yTAFn90 (Apone et al.), 2368-2380
interaction of Swel regulators with histone amino
termini (Ma et al.), 1327-1340 Tupl with histones H3 and H4 (Ed-
mondson et al.), 1247-1259
masked expression of copper transport gene by Ty2 (Knight et al.), 1917-1929
NHP6A/B role in transcriptional stim- ulation (Paull et al.), 2769-2781
Npl3p role in RNA export (Lee et al.}, 1233-1246
parallel sensory branches for DNA damage signaling (Navas et al.), 2632-2643
preferential integration of Ty5 into re- gions of silent chromatin (Zou et al.), 634-645
protein product homolog role in RAD51-independent recombi- nation (Bai and Symington), 2025-2037
Rap l protein role in silencing at non- telomeric regions {Marcand et al.), 1297-1309
redundancy of MSH3 and MSH6 in mismatch repair (Marsischky et al.I, 407-420
regions of RPA subunits with similar- ity to E. coli SSB protomer (Phil- ipova et al.), 2222-2233
regulation and specification of replica- tion origins (Diffley), 2819- 2830 Review
regulation of mRNA export during stress (Saavedra et al.), 1608- 1620
silencers role in inheritance of repres- sion (Holmes and Broach), 1021-1032
single-stranded telomere end-binding protein properties of Est 1 (Virta- Pearlman et al.), 3094-3104
Spkl/Rad53 regulation by Mecl-de- pendent protein phosphoryla- tion (Sun et al.), 395-406
targeting of retrotransposon Tyl to up- stream regions of RNA pol II- transcribed genes (Devine and Boekel, 620-633
TBP role in rDNA transcription (Stef- fan et al.), 2551-2563
3'-+ 5' exonuclease role in 5.8S RNA synthesis (Mitchell et al.), 502- 513
Tor signaling role in nutrient stimula- tion of Tap42 association with PP2A (DiComo and Arndt), 1904-1916
U2 snRNP proteins role in spliceo- some assembly (Gozani et al.), 233-243
UAF role in RNA pol I preinitiation complex formation (Keys et al.), 887-903
Sadl, regulation by Mecl-dependent pro- tein phosphorylation (Sun et al.), 395M06
SAP 145 binding upstream of branchpoint se-
quence (Gozani et al.), 233-243
homology of Saccharomyces cerevi- siae CUS1 gene product (Wells et al.), 220-232
SAPIa, inability of Pax-5 to recruit to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211
SAPKs. See Protein kinases, stress-acti- vated
Satellite cells, role of MyoD in myogenic stem cell function (Megeney et al.), 1173-1183
SBF. See SCB-binding factor SC35, role in splicing (Manley and
Tacke), 1569-1579 Review SCB-binding factor, cell-cycle regulation
(Koch et al.}, 129-141 Schizosaccharomyces pombe. See also
Yeast, fission d m f l / m i d l role in positioning of divi-
sion septum (Sohrmann et al.), 2707-2719
regulation of Atfl by Spcl in response to stress
(Shiozaki and Russell), 2276- 2288
Atfl by stress-activated kinase Styl (Wilkinson et al.), 2289-2301
S-phase onset by ORC1 homolog orpl (Grallert and Nurse), 2644- 2654
Rum l inhibition of Cdc2 kinase and interaction with Cdcl8 (Jalle- palli and Kelly), 541-552
Schwann cells, effects of Tst-1/Oct-6/ SCIP deletion in mice (Berming- ham et al.), 1751-1762
SCID activation of DNA damage checkpoint
by V(D)J recombination in lym- phocyte precursors (Guidos et al.), 2038-2054
cooperativity with p53 in tumorigene- sis (Nacht et al.), 2055-2066
mice (scid}, role of p53 in radiation-in- duced differentiation and rescue of V(D)J rearrangement (Bogue et al.), 553-565
SCIP, effects of gene deletion in mice (Bermingham et al.), 1751-1762
Scr. See Sex combs reduced Scrapie, de novo generation of prion in-
fectivity in mice (Telling et al.), 1736-1750
SDI- 1. See p21 Secondary structure, mRNA, role of HF-I
in rpoS translation (Muffler et al.), 1143-1151
Segment-polarity genes, role of porcu- pine in Wingless processing (Ka- dowaki et al.), 3116--3128
Segmentation Fab-7
attenuation of enhancer-promoter interactions in Drosophila (Zhou et al.), 3195-3201
as chromatin domain boundary in
3248 GENES & DEVELOPMENT
Drosophila (Hagstrom et al.), 3202-3215
role of bagpipe and serpent in Droso- phila (Azpiazu et al.), 3183- 3194
Selectivity, determinants in Xer site-spe- cific recombination (Blakely and Sherratt), 762-773
sere-4, role in neuronal and mesodermal development (Basson and Hor- vitz), 1953-1965
Sensory organs. See Organs, sensory Septation, role of SpoIIE in asymmetric
cell division (Feucht et al.), 794- 8O3
Septins, role of Axl2p in bud-site selec- tion in yeast (Roemer et al.), 777-793
serpent, role in segmentation and specifi- cation of Drosophila mesoderm (Azpiazu et al.), 3183-3194
Serrate, complementarity of Delta in Drosophila wing development (Doherty et at.), 421-434
Sertoli cells, accumulation of lipids in RXR~-deficient mice (Kastner et al.), 80-92
Seven-transmembrane proteins, encoded by lin-I7 in C. elegans (Sawa et al.), 2189-2197
Sevenless regulation of prospero through activa-
tion Rasl/MAP kinase pathway in R7 photoreceptors (Kauff- mann et al.), 2167-2178
role of PP2A in signaling pathway (Wassarman et al.), 272-278
seven-up, negative regulation by Droso- phila Lozenge (Daga et at.), 1194-1205
Sex combs reduced, control of trachea- less expression in the Droso- phila salivary duct (Isaac and Andrew), 103-117
Sex determination assembly of specific SR protein com-
plexes at the doublesex splicing enhancer (Lynch and Maniatis), 2089-2101
role of FEM-2 in C. elegans (Chin-Sang and Spence), 2314-2325
Sexual differentiation. See Differentia- tion, sexual
Sey phenotype. See Small eye phenotype SF2. See ASF/SF2 SH2 domain, in novel pl3OC~-related
protein Sin (Alexandropoulos and Baltimore), 1341-1355
SH3 domain, role in interaction of c-Src with Sin (Alexandropoulos and Baltimore), 1341-1355
Shc, role of inositol phosphatases in signal transduction (Majerus), 1051-1053 Minireview
short gastrulation, prevention of Dpp au- toactivation and suppression of
neurogenesis (Biehs et al.), 2922-2934
shotgun, as encoding Drosophila E-cad- herin (Uemura et al.), 659-671; (Tepass et al.), 672-685
Shuttling, of Npl3p between cytoplasm and nucleus in yeast (Lee et al.), 1233-1246
Sialidosis, role of mutant human neur- aminidase gene (Bonten et al.), 3156-,3169
~-factor HF-I role in rpoS translation (Muffler
et al.), 1143-1151 interaction of SpoIIAB with (r F in B.
subtilis (Decatur and Losick), 2348-2358
regulation of sigma B by stress response signaling in B. subtitis (Yang et al.), 2265-2275
release of cr ~ by SpolIE phosphoryla- tion of SpoIAA-P (Feucht et al.), 794-803
Signal sequence, role of anticodon for tRNA import into mitochon- dria (Rusconi and Cech), 2870- 2880
Signal transduction activation of
dorsal by Toll, tube, and pelle (Nor- ris and Manley), 862-872
JNK/SAPK pathway by HPK1 (Hu et al.), 2251-2264
analysis of residues important for Torso signaling (Cleghon et al.), 566-577
~-catenin role in embryogenesis (Mil- ler and Moon), 2527-2539 Re- view
characterization of a novel nuclear ki- nase in human cells (Denis and Green), 261-271
conserved signaling through ceramide- activatcd protein phosphatase in Saccharomyces cerevisiae (Nickels and Broach), 382-394
Delta and Serrate as compartment-spe- cific signals in the wing disc (Doherty et al.), 421-434
DIG1 and DIG2 as two novel MAP ki- nase targets in S. cerevisiae (Cook et al.), 2831-2848
FEM-2 phosphatase role in C. elegans sex determination (Chin-Sang and Spence), 2314-2325
function of human TOR homolog RAFT1 kinase (Alarcon et al.), 279-288
inositol phosphatases role (Majerus), 1051-1053 Minireview
JNK pathway mediating morphogene- sis and an immune response in Drosophila (Sluss et al.), 2745- 2758; (Riesgo-Escovar et al.), 2759-2768
MAP kinase and cAMP regulation of
rice blast fungus M. grisea infec- tion (Xu and Hamer), 2696- 2706
MIS pathway role in mammalian sex- ual differentiation (Mishina et al.), 2577-2587
p150 ship and Fms signal transduction (Lioubin et al.), 1084-1095
parallel sensory branches for DNA damage signaling in S. cerevi- siae (Navas et al.), 2632-2643
participation of Madr2 in the activin pathway (Baker and Harland), 1880-t889
regulation of Atfl by Spcl in S. pombe (Shiozaki
and Russell), 2276-2288 Atfl by Styl in S. pombe (Wilkinson
et al.), 2289-2301 developmental pathways by ERK2
in Dictyostelium discoideum (Gaskins et al.), 118-128
Rasl-mediated signaling by PP2A (Wassarman et al.), 272-278
in response to stress in B. subtilis (Yang et al.), 2265-2275
role in MAPK signaling pathway (Therrien et al.), 2684-2695
tamou role in Drosophila develop- ment (Takahisa et al.), 1783- 1795
Signaling ~3-catenin and Xgsk-3 role in Xenopus
(Yost et al.), 1443-1454 CF2 role in EGF-R-activated dorsoven-
tral patterning (Hsu et al.), 1411-1421
compartment-specific, role of Delta in Drosophila wing development (Doherty et al.), 421-434
effects of erythropoietin receptor gene inactivation (Lin et al.), 154- 164
Heartless role in Drosophila develop- ment (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017
intercellular branched C-factor signaling path-
way in Myxococcus (Sogaard- Andersen et al.), 740-754
induction of patched by hedgehog in mice (Goodrich et al.), 301-312
midline, PKA regulation of Hedgehog signaling in vertebrates (Ham- merschmidt et al.), 647-658
Silencers, transcriptional, preferential integration of Ty5 into regions of silent chromatin (Zou et al.), 634-645
Silencing and chromatin structure (Kingston et
al.), 905-920 Review Rap l protein role at nontelomeric re-
gions (Marcand et al.), 1297- 1309
GENES & DEVELOPMENT 3249
silencers role in inheritance of repres- sion in yeast (Holmes and Broach), 1021-1032
suppression of position-effect varie- gation by transcriptional en- hancers (Wakers et al.), 185- 195
telomeres role {Maillet et al.}, 1796- 1811
of X-linked genes in response to DNA hypomethylation (Panning and Jaenisch), 1991-2002
Sin protein, role in c-Src activation (A1- exandropoulos and Baltimore), 1341-1355
SIN4, incomplete penetrance of tran- scriptional defect suppression in mutant yeast strains (Jiang and Stillman), 604-619
Sina, rote in up-regulation of prospero transcription during Drosophila eye development {Kauffmann et al.), 2167-2178
Single-stranded DNA-binding protein properties of Estl (Virta-Pearlman et
al.), 3094-3104 similarity of yeast RPA to E. coli SSB
protomer (Philipova et al.), 2222-2233
Sir proteins and chromatin structure (Kingston et
al.), 905-920 Review effect of protein concentration on si-
lencing (Maillet et al.), 1796- 1811
increased rate of telomeric rapid dele- tion caused by Sir3p mutations (Li and Lustig), 1310-1326
sequestration at telomeres by Rap 1 pro- tein (Marcand et al.), 1297-1309
SIT4 association of protein product with
Tap42 (DiComo and Amdt), 1904-1916
as encoding the catalytic subunit of ce- ramide-activated protein phos- phatase in S. cerevisiae (Nickels and Broach}, 382-394
Size control, telomeric, novel mecha- nism in yeast (Li and Lustig), 1310-1326
Skin, absence of plectin in MD-EBS pa- tients (McLean et al.), 1724- 1735
SL RNA. See Spliced leader RNA SL1 RNA, role of in C. elegans embryo-
genesis (Ferguson et al.), 1543- 1556
SL2 RNA, substitution for SL1 RNA in C. elegans embryogenesis (Fer- guson et al.), 1543-1556
SLBP. See Stem-loop binding protein Small eye phenotype, caused by muta-
tions in mouse Pax6 {Quinn et al.), 435--446
Small lung cell carcinoma, in Rb +/-
mice (Nikitin and Lee), 1870- 1879
Small nuclear RNA CUS1 as suppressor of U2 snRNA
cold-sensitive mutations (Wells et al.), 220-232
effects of U I snRNA on 5' splice site selection {Hwang and Cohen), 338-350
redundant interactions between U2 and U6 snRNAs during splicing (Field and Friesen), 489-501
U 1 snRNA role in 5' splice site selection {Hwang and Cohen), 338-350
smaug protein, translational repression of unlocalized nanos mRNA {Smibert et al.l, 2600-2609
Snail, as transcriptional repressor (Gray and Levine), 700-710
SNF1, glucose regulation of protein-pro- tein interactions (Jiang and Carlson), 3105-3115
snRNA. See Small nuclear RNA snRNP protein complexes, role in spli-
ceosome assembly (Gozani et al.), 233-243
snRNPs, and activation of polyadenyla- tion by intron enhancer (Lou et al.), 208-219
Somites, role of BMPs in patterning (Hogan), 1580--1594 Review
Somitogenesis, caudal, role of mouse Wnt-3a (Greco et al.), 313-324
Spa2, AXL2 as high copy suppressor in spa2~ cdclO-lO mutant strains (Roemer et al.), 777-793
Spcl, regulation of Atfl in S. pombe (Shiozaki and Russell), 2276- 2288
Spermatogenesis defects in ATM-deficient mice (Xu et
al. }, 2411-2422 effects of
Bmp8b inactivation in mice (Zhao et al.), 1657-1669
RXR~3 inactivation in mice (Kastner et al.), 80-92
Spkl, regulation by Mecl-dependent protein phosphorylation {Sun et al.), 395-406
Splice site, 5', role of CBC in facilitating UlsnRNP association (Lewis et al.), 1683-1698
Spliced leader RNA, role of SL1 RNA in C. elegans embryogenesis (Fer- guson et al.), 1543-1556
Spliceosomal complex A, role of U2 snRNP proteins in assembly (Gozani et al.), 233-243
Spliceosome CUS1 role gene product in assembly
(Wells et al.), 220-232 RNA helicase-like protein HRH1 role
in facilitating release of spliced mRNA (Ohno and Shimura), 997-1007
U2 snRNP proteins role in assem- bly(Gozani et al.), 233-243
Splicing ASF/SF2 role in cell viability (Wang et
al.), 2588-2599 assembly of specific SR protein com-
plexes at the doublesex en- hancer (Lynch and Maniatis), 2089-2101
CUS1 gene product role in spliceo- some assembly (Wells et al.), 220-232
differential, conversion of oLNAC to myotube-specific factor by in- clusion of proline-rich exon (Yotov and St-Arnaud), 1763- 1772
effects of U1 snRNA on 5' splice site selection (Hwang and Cohen), 338-350
enhancers, interactions with SR pro- teins (Manley and Tacke), 1569-1579 Review
function of the U2AF 35-kD subunit (Zuo and Maniatis), 1356-1368
HRH1 role in facilitating release of spliced mRNA from the spliceo- some (Ohno and Shimura), 997- 1007
hrp45 role in binding to exonic pre- mRNA and nucleocytoplasmic transport (Alzhanova-Ericsson et al.), 2881-2893
Mudl3p as yeast homolog of CBP20 (Colot et al.), 1699-1708
nuclear cap-binding complex role in pre-mRNA recognition (Lewis et al.), 1683-1698
redundant interactions between U2 and U6 snRNAs (Field and Frie- sen), 489-501
splice-site containing poly[A) en- hancer (Lou et al.), 208-219
SR proteins (Manley and Tacke), 1569-1579 Review
U2 snRNP proteins in spliceosome assembly (Gozani et al.), 233- 243
SpoA, dependence of switch to bipolar localization of FtsZ in B. subti- lis (Levin and Losick), 478-488
SpoIIAB, interaction of SpoIIAB with O "F
in B. subti l is (Decatur and Losick}, 2348-2358
Sporulation bifunctionality of SpoIIE in asymmet-
ric cell division and cell-specific transcription (Feucht et al.), 794--803
and bipolar localization of FtsZ in B. subti l is (Levin and Losick), 478--488
role of extracellular peptide in B. sub- tilis (Solomon et al.), 2014-- 2024
SR proteins
3250 GENES & DEVELOPMENT
ASF/SF2 role in cell viability (Wang et al.), 2588-2599
assembly of specific complexes at the doublesex splicing enhancer (Lynch- and Maniatis), 2089- 2101
hrp45 role in binding to exonic pre- mRNA and nucleocytoplasmic transport (Alzhanova-Ericsson et al.), 2881-2893
role in splicing (Manley and Tacke), 1569-1579 Review
U2AF 35-kD subunit in splicing (Zuo and Maniatis), 1356-1368
SRB proteins, findings presented at Cold Spring Harbor meeting (McKnight), 367-381 Meeting commentary
Src, role of Sin in c-Src activation (Alex- andropoulos and Baltimore), 1341-1355
SREBP 1, role in adipocyte differentiation (Kim and Spiegelman), 1096- 1107
SREBPs. See Sterol regulatory element binding proteins
SSA1, nucleocytoplasmic export of mRNA during stress in yeast (Saavedra et al.}, 1608-1620
SSA4, nucleocytoplasmic export of mRNA during stress in yeast (Saavedra et al.), 1608-1620
SSB. See Single-stranded DNA-binding protein
SSN6/TUP1 and chrornatin structure (Kingston et
al.), 905-920 Review interaction of Tupl with histones H3
and H4 (Edmondson et al.), 1247-1259
Start, activation of bound SBF during (Koch et al.), 129-141
Staufen, role of interaction with Oskar in Drosophila pole plasm for- mation (Breitwieser et al.}, 2179-2188
Stem-loop binding protein, role in processing histone pre-mRNA (Wang et al.), 3028-3040
Sterility, male, in RXR[~-deficient mice (Kastner et al.), 80-92
Sterol regulatory element binding pro- teins, mediation of transcrip- tional activity by CBP (Oliner et al.), 2903-2911
Stress response regulation of Atfl by Spcl in S. pombe
(Shiozaki and Russell), 2276- 2288
regulation of Atfl by Styl in S. pombe (Wilkinson et al.), 2289-2301
serine kinases and phosphatases in B. subtilis (Yang et al.), 2265-2275
Styl, regulation of Atfl in S. pornbe (Wilkinson et al.), 2289-2301
Substrate specificities, of CED-3/ICE-
like proteases (Xue et al.), 1073- 1083
SucI/Cksl proteins, role of Xenopus ho- molog Xe-p9 in cell cycle con- trol (Patra and Dunphy), 1503- 1515
Superoxide dismutase, activation of CUP1 in yeast lacking SOD1 (Liu and Thiele), 592-603
SurA, role in outer membrane porin as- sembly in E. coli (Rouvihre and Gross), 3170-3182
SV40 enhancer, in the study of position-ef-
fect variegation (Wakers et al.), 185-195
large T antigen release of active E2F in presence of
dominant-negative cdk2 (Hof- mann and Livingston), 851-861
TAF-like function (Damania and A1- wine), 1369-1381
Swel kinase, interaction of regulators with histone amino termini (Ma et al.), 1327-1340
SWI/SNF complex function of Swp73 component in yeast
(Cairns et al.), 2131-2144 identification of mammalian counter-
parts (Wang eta!.), 2117-2130 role in activator-dependent release of
transcriptional pausing (Brown et al.}, 1479-1490
role in restructuring chromatin (Kings- ton et al.), 905-920 Review
swirl, role in zebrafish development (Hammerschmidt et al.1, 2452- 2461
Swp73p, function in yeast Swi/Snf com- plex (Cairns et al.), 2131-2144
Synthesis-dependent strand annealing, role in intron mobility (Mueller et al.), 351-364
Synthetic lethality, for isolating histone amino termini-interacting pro- teins (Ma et al.), 1327-1340
T
T antigen. See SV40 large T antigen T cells
cooperativity of p53 and SCID in lym- phomagenesis (Nacht et al.1, 2055-2066
rearrangement of Notch1 in mouse thymomas (Girard et al.), 1930- 1944
regulation of bcI-2 by domnant inter- fering Myb (Taylor et al.), 2732- 2744
T-cell receptor, coincident regulation of cell cycle and clonality during development (Hoffman et al.), 948-962
T/EBP. See Thyroid-specific enhancer- binding factor
T4 phage, intron mobility (Mueller et al.), 351-364
TAFs. See TATA-box-binding protein- associated factors
Tail bud, role of mouse Wnt-3a in forma- tion (Greco et al.), 313-324
tamou, Drosophila homolog of ZO-1 (Takahisa et al.), 1783-1795
TANK, induction of NF-KB (Cheng and Baltimore), 963-973
Tap42, nutrient stimulation of Tap42 as- sociation with PP2A (DiComo and Arndt), 1904-1916
Target selection, preference of Tn7 for conjugating plasmids {Wolkow et al.), 2145-2157
Targeting, of Tyl integration to up- stream regions of RNA pol III- transcribed genes (Devine and Boeke), 620-633
TATA box assembly of the TFIID-TFIIA complex
(Chi and Carey), 2540-2550 role of CIF as cofactor for TFIID-
dependent initiator function {Kaufmann et al.), 873-886
TATA-box-binding protein functional epitopes for Pol II transcrip-
tion (Bryant et al.), 2491-2504 role in
binding of Drosophila TFIID to downstream basai promoter el- ement (Burke and Kadonaga}, 711-724
directing TFIIIB binding to tRNA genes (Joazeiro et al.), 725- 739
Pol II transcription (Orphanides et al.), 2657-2683 Review
rDNA transcription in S. cerevisiae (Steffan et al.1, 2551-2563
TATA-box~ protein-associated fac- tors
in vivo function of yeast TAFn90 (Apone et al.), 2368-2380
role in binding of Drosophila TFIID to down-
stream basal promoter element (Burke and Kadonaga), 711-724
inhibition of activator-dependent transcription (Segil et al.), 2389- 2400
Pol II transcription (Orphanides et al.), 2657-2683 Review
role of CIF as cofactor for TFIID- dependent initiator function (Kaufmann et al.), 873-886
similar function of SV40 large T anti- gen (Damania and Alwine), 1369-1381
TATA-less genes, codirection of TFIIIB binding to tRNA genes by TBP and TFIIIC (Joazeiro et al.), 725- 739
TBP. See TATA-box-binding protein Tcl /mar iner family, in vitro transposi-
GENES & DEVELOPMENT 3251
tion of Tcl in C. elegans (Vos et al.), 755-761
Telomeres preferential integration of Ty5 into re-
gions of silent chromatin (Zou et al.), 634-645
role in silencing (Maillet et al.), 1796- 1811
role of cap-prevented recombination in maintenance (McEachern and Blackburn), 1822-1834
single-stranded telomere end-binding protein properties of Est 1 {Virta- Pearlman et al.), 3094-3104
size control in yeast (Li and Lustig), 1310-1326
Telorneric position effect. See Position effect, telomeric
Telomeric rapid deletion. See Rapid de- letion, telomeric
TER1, effect of deletion in Kluyveromy- ces lactis (McEachern and Blackburn), 1822-1834
Testis degeneration caused by Bmp8b inacti-
vation in mice (Zhao et al.), 1657-1669
role of MIS in mammalian sexual dif- ferentiation (Mishina et al.), 2577-2587
Tetrahymena, anticodon as signal se- quence for tRNA import into mitochondria (Rusconi and Cech), 2870-2880
TFC4, and flexible alignments between TFIIIB and TFIIIC (Joazeiro et al.), 725-739
TFE-3, comparison to Myc in gene acti- vation (Desbarats et al.), 447- 460
TFIIA functional TBP epitopes for Pol II tran-
scription (Bryant et al.), 2491- 2504
role in Pol II transcription (Orphanides et
al.), 2657-2683 Review Ras-mediated photoreceptor deter-
mination (Zeidler et al.), 50-59 role of complex formation with TFIID
in gene activation (Chi and Carey), 2540-2550
TFIIB findings presented at Cold Spring Har-
bor meeting (McKnight), 367- 381 Meeting commentary
role in Pol II transcription (Orphanides et al.), 2657-2683 Review
TFIID binding to downstream basal promoter
element in Drosophila (Burke and Kadonaga), 711-724
CIF role as cofactor for initiator func- tion (Kaufmann et al.), 873- 886
complex formation role with TFIIA in
gene activation (Chi and Carey), 2540--2550
findings presented at Cold Spring Har- bor meeting (McKnight), 367- 381 Meeting commentary
functional TBP epitopes for Pol II tran- scription (Bryant et al.), 2491- 2504
inhibition of activator-dependent tran- scription (Segil et al.}, 2389- 2400
role in Pol II transcription (Orphanides et al.), 2657-2683 Review
TAF-like function for SV40 large T anti- gen (Damania and Alwine), 1369-1381
TFIIE, role in Pol II transcription (Or- phanides et al.), 2657-2683 Re- view
TFIIH in Pol II transcription (Orphanides et
al.), 2657-2683 Review role of XPB and XPD in p53-dependent
apoptosis (Wang et al.), 1219- 1232
TFIIIB, codirection of binding to tRNA genes by TBP and TFIIIC (Joazeiro et al.), 725-739
TFIIIC, role in directing TFIIIB binding to tRNA genes (Joazeiro et al.), 725-739
TGF-~. See Transforming growth factor
TGF-[3. See Transforming growth factor 13 family
Thymocytes coincident regulation of cell cycle and
clonality during T-cell receptor development (Hoffman et al.), 948-962
p53 rescue of V(D)J rearrangement in scid mice (Bogue et al.), 553- 565
Thyroid-specific enhancer-binding fac- tor, role of in organogenesis (Kimura et al.), 60--69
Tissue specificity conversion of aNAC to myotube-spe-
cific factor (Yotov and St-Ar- naud), 1763-1772
effect of liver-specific p21 overexpres- sion in transgenic mice (Wu et al.), 245-260
Pax-5 recruitment of Ets proteins to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211
PU. 1 ternary complex formation with lymphoid-restricted IRF Pip (Brass et al.), 2335-2347
sequence-specific DNA binding of B-cell POU domain coactivator OCA-B (Cepek et al.), 2079- 2088
Tn7, conjugating plasmids as preferred targets (Wolkow et al.), 2145- 2157
TNFR. See Tumor necrosis factor recep- tor
Toll receptor, functional interactions with pelle kinase and tube (Nor- ris and Manley), 862-872
TOP1, role in mitotic chromosome con- densation in S. cerevisiae (Castafio et al.), 2564-2576
Topoisomerases, role in chromosome condensation in S. cerevisiae (Castafio et al.), 2564-2576
Tor proteins rapamycin-sensitive function in yeast
(Alarcon et al.), 279-288 role in stimulation of Tap42 associa-
tion with PP2A {DiComo and Arndt), 1904-1916
torpedo/DER signaling system, role in polarization of body axes during Drosophila oogenesis (Ray and Schtipbach), 1711-1723 Review
Torso, analysis of key residues for signal- ing (Cleghon et al.), 566-577
TPD3, as encoding the regulatory sub- unit of ceramide-activated pro- tein phosphatase in S. cerevi- siae (Nickels and Broach), 382- 394
Trachea expression of bHLH-PAS protein by
trachealess in Drosophila (Wilk et al.), 93-102
role of Breathless in patterning cell mi- gration and branching in Droso- phila (Lee et al.), 2912-2921
trachealess as encoding bHLH-PAS protein (Wilk
et al.), 93-102 role in embryonic tube formation
(Isaac and Andrew), 103-117 TRAF family, TRAF2 as TANK co-in-
ducer of NF-KB activation (Cheng and Baltimore), 963-973
trans-splicing, role of SL1 RNA in C. el- egans embryogenesis (Ferguson et al.), 1543-1556
Transcription activation of
dorsal by Toll, tube, and pelle (Nor- ris and Manley), 862-872
metallothionein by oxidative stress via HSF (Liu and Thiele), 592- 603
activator-dependent release of tran- scriptional pausing (Brown et al.), 1479-1490
altered intracellular receptor activa- tion (Starret al.), 1271-1283
basal machinery binding of Drosophila TFIID to
downstream basal promoter el- ement (Burke and Kadonaga), 711-724
codirection of TFIIIB binding to tRNA genes by TBP and TFIIIC (Joazeiro et al.), 725-739
3252 GENES & DEVELOPMENT
corepressor requirement for Drl (Mermelstein et al.), 1033- 1048
functional TBP epitopes for Pol II transcription (Bryant et a].), 2491-2504
inhibit ion of activator-dependent transcription (Segil et al.), 2389- 2400
role in Pol II transcription (Or- phanides et al.), 2657-2683 Re- view
role of CIF as cofactor for TFIID-depen-
dent initiator function (Kauf- mann et al.}, 873-886
TFIIA in Ras-mediated photore- ceptor determinat ion (Zeidler et al.), 50--59
TFIIA-TFIID complex formation in gene activation (Chi and Carey), 2540--2550
TAF-like function for SV40 large T antigen (Damania and Alwine), 1369-1381
binding of Drosophila TFIID to down- stream basal promoter ele- ment (Burke and Kadonaga), 711-724
CBP as a coactivator of c-Myb (Dai et al.), 528-540
cell-specific, role of SpoIIE in regulat- ing ~-factor in B. subtilis (Feucht et al.), 794-803
codirection of TFIIIB binding to tRNA genes by TBP and TFIIIC {Joazeiro et al.), 725-739
conversion of ~NAC to myotube-spe- cific transcription factor (Yotov and St-Arnaud), 1763-1772
corepressor requirement for Drl-medi- ated repression (Mermelstein et al.), 1033-1048
coupling of cell lineage asymmetry with unc-86 transcription (Baumeister et al.), 1395-1410
effect of enhancers on position-effect variegation (Wakers et al.), 185- 195
epigenetic effects in yeast caused by mutat ions in nuclear actin-re- lated protein (Jiang and Still- man), 604-619
factors activation of dorsal by Toll, tube and
pelle (Norris and Manley), 862- 872
bHLH-PAS protein as inducer of Drosophila tracheal cell fates (Wilk et al.), 93-102
bipolar localization of FtsZ in B. subtilis (Levin and Losick), 478-488
CBP as a coactivator of c-Myb (Dai et al.), 528-540
conversion of RNAC to myotube-
specific factor (Yotov and St-Ar- naud), 1763-1772
function of Swp73 in yeast Swi/Snf complex (Cairns et al.), 2131- 2144
gene activation by GAL4-GALl lP interaction (Farrell et al.), 2359- 2367
identification of mammalian SWI/ SNF complexes (Wang et al.), 2117-2130
inhibition of ATF-2 activation by its DNA-binding domain {Li and Green), 517-527
interaction of SpoIIAB with cr F (De- catur and Losick), 2348-2358
KrGppel and snail as transcriptional repressors (Gray and Levine), 700-710
mediation of SREBP transcriptional activity by CBP (Oliner et al.), 2903-2911
novel bicoid-related homeo box fac- tor Ptxl (Lamonerie et al.), 1284-1295
nuclear colocalization of AP- ETALA3 and PISTILLATA (McGonigle et al.), 1812-1821
Pip autoinhibition and ternary com- plex formation with PU. 1 (Brass et al.), 2335-2347
regulation of Atfl by Spcl in S. pombe
(Shiozaki and Russell), 2276- 2288
Atfl by Styl in S. pombe (Wilkin- son et al.), 2289-2301
epithelial growth and differentia- tion by nude locus product Whn (Brissette et al.), 2212-2221
HSF1 by phosphorylation (Knauf et al.), 2782-2793
kidney development by BF-2 (Ha- tini et al.), 1467-1478
relationship of trachea Jess gene product to Drosophila single- minded protein (Isaac and An- drew), 103-117
relationship of trachealess gene product to human hypoxia-in- ducible factor- 1~ (Isaac and An- drew), 103-117
RNA Pol II general factors (Or- phanides et al.), 2657-2683 Re- view
role of ADD1/SREBP1 in adipocyte dif-
ferentiation (Kim and Spiegel- man), 1096-1107
CF2 in EGF-R-activated dorsoven- tral patterning (Hsu et al.), 1411-1421
EKLF in human 6-globin gene competition (Wijgerde et al.), 2894-2902
Rb interaction with C/EBPs in ad-
ipocyte terminal differentiation (Chen et al.), 2794-2804
UAF in RNA pol I preinitiation complex formation (Keys et al.), 887-903
use of HSF1 activation domain to readthrough transcriptional pausing (Brown et al.), 1479- 1490
findings presented at Cold Spring Har- bor meeting (McKnight), 367- 381 Meeting commentary
function of Swp73 in yeast Swi/Snf complex (Cairns et al.), 2131- 2144
functional TBP epitopes for Pol II activity (Bryant et al.), 2491- 2504
gene activation by GAL4-GAL11P in- teraction (Farrell et al.), 2359- 2367
identification of mammal ian SWI/ SNF complexes (Wang et al.), 2117-2130
in vitro, reconsti tution of initiator ac- tivity (Kaufmann et al.), 873- 886
in vivo function of yeast TAFn90 (Apone et al.), 2368-2380
independent regulation of neighboring genes (Merli et al.), 1260-1270
interaction of Tupl with histones H3 and H4 (Edmondson et al.), 1247-1259
localization of TFIID and inhibit ion of activation {Segil et al.), 2389- 2400
masked expression of yeast copper transport gene by Ty2 (Knight et al.), 1917-1929
mechanism of hepatic specification of gut endoderm (Gualdi et al.), 1670-1682
mediation of SREBP activity by CBP (Oliner et al.), 2903-2911
RNA Pol II general factors (Orphanides et al.), 2657-2683 Review
role of chromatin in activation and repres-
sion (Kingston et al.), 905-920 Review
CIF as cofactor for TFIID-dependent initiator function (Kaufmann et al.), 873-886
EKLF in human ~-globin gene com- petition {Wijgerde et al.), 2894- 2902
EVES motif in c-Myb regulation (Dash et al.), 1858-1869
NF-KB in recrui tment of RNA poly- merase II to the HIV-1 promoter (Pazin et al.), 37-49
NURF in activation (Kingston et al.), 905-920 Review
p53 (Ko and Prives), 1054-1072 Re- view
GENES & DEVELOPMENT 3253
S. cerevisiae NHP6A/B in stimula- tion (Paull et al.), 2769-2781
short-range repressors in Drosophila embryos (Gray and Levine), 700--710
silencers in inheritance of repres- sion in yeast (Holmes and Broach), 1021-1032
SWI/SNF in activation (Kingston et al.}, 905-920 Review
TBP in rDNA expression in S. cere- visiae (Steffan et al.), 2551-2563
UAF in RNA pol I preinitiation complex formation (Keys et al.), 887-903
sequence-specific DNA binding of B-cell POU domain coactivator OCA-B (Cepek et al.), 2079- 2088
TAF-like function for SV40 large T an- tigen (Damania and Alwine), 1369-1381
targeting of retrotransposon Ty 1 to up- stream regions of RNA pol II- transcribed genes (Devine and Boeke), 620--633
Transfer RNA, anticodon as signal se- quence for import into mito- chondria (Rusconi and Cech), 2870-2880
Transformation malignant, in Rb +/- mice {Nikitin
and Lee), 1870-1879 suppression by PKC-~ (Kieser et al.),
1455-1466 Transformer proteins, role in recruiting
SR proteins to the doublesex splicing enhancer (Lynch and Maniatis), 2089-2101
Transforming growth factor a, gene in- activation as compared to kera- tinocyte growth factor gene inactivation (Guo et al.), 165- 175
Transforming growth factor [~ family regulation of tumor cell plasticity by
TGF-[~ (Oft et al.), 2462-2477 role of MIS in mammalian sexual dif-
ferentiation (Mishina et al.), 2577-2587
sog prevention of Dpp autoactivation and suppression of neurogenesis (Biehs et al.), 2922-2934
Transgenesis, Tcl as potential vector (Vos et al.), 755-761
Transgenic flys for studying binding of TFIID to down-
stream basal promoter element {Burke and Kadonaga), 711-724
for studying the regulation of Rasl- mediated signaling by PP2A (Wassarman et al.), 272-278
Transgenic mice abnormal kidney development in ani-
mals expressing wild-type p53 (Godley et al.l, 836-850
de novo generation of prion infectivity (Telling et al.), 1736--1750
in study of tissue-specific inactivation of p53 tumor suppression (Bow- man et al.], 826-835
Translation down-regulation of LIN-14 mediated
by 3' UTR (Ha et al.), 3041- 3050
initiation, ribosome jumping in virus- infected and heat shocked cells {Yueh and Schneider), 1557- 1567
regulation of nanos mRNA (Daha- nukar and Wharton), 261 0-2620
repression of unlocalized nanos mRNA (Smibert et al.), 2600- 2609
Transmembrane proteins. See also Seven-transmembrane proteins
as encoded by Drosophila porcupine (Kadowaki et al.), 3116-3128
possible structure of the mouse patched gene product (Goodrich et al.), 301-312
Transport, nucleocytoplasmic, regula- tion of mRNA export during stress in yeast (Saavedra et al.), 1608-1620
Transposition of C. elegans Tcl in vitro (Vos et al.),
755-761 conjugating plasmids as preferred tar-
gets for Tn7 (Wolkow et al.), 2145-2157
integration of Ty5 into regions of si- lent chromatin {Zou et al.), 634- 645
severe reduction of P element excision in mus309 mutants (Beall and Rio), 921-933
targeting of Ty 1 to upstream regions of RNA pol III-transcribed genes (Devine and Boeke), 620-633
Transposon tagging, use in cloning Glossyl5 in maize (Moose and Sisco), 3018-3027
Transposons conjugating plasmids as preferred tar-
gets for Tn7 (Wolkow et al.), 2145-2157
in vitro transposition of Tcl in C. ele- gans (Vos et al.), 755-761
integration of Ty5 into regions of si- lent chromatin (Zou et al.), 634- 645
masked expression of yeast copper transport gene by Ty2 (Knight et al.), 1917-1929
targeting of Tyl to upstream regions of RNA pol III-transcribed genes (Devine and Boeke), 620--633
used to study dif resolvase site inser- tions in E. coli (Kuempel et al.), 1162-1171; Corrigendum, 1709
Traveling waves, in chemical and biolog-
ical systems (Sager}, 2237-2250 Review
TRD. See Rapid deletion, telomeric TRF4, role in mitotic chromosome con-
densation in S. cerevisiae (Castaflo et al.), 2564-2576
Trk family, role of TrkB and TrkC in pro- moting neuron survival (Min- ichello and Klein), 2849-2858
tRNA. See Transfer RNA Tst-1, effects of gene deletion in mice
{Bermingham et al.), 1751-1762 Tube, functional interactions with pelle
kinase and Toll receptor (Norris and Manley), 862-872
Tubulogenesis E-cadherin in Drosophila epithelial
cell rearrangement (Uemura et al.), 659-671
role of trachealess in Drosophila (Isaac and Andrew), 103-117
Tumor cells, regulation of plasticity by TGF-~ and Ha-Ras (Oft et al.), 2462-2477
Tumor formation. See Tumorigenesis Tumor necrosis factor receptor, role of
TANK in signaling pathway {Cheng and Baltimore), 963- 973
Tumorigenesis in ATM-def ic ient mice (Xu et al.),
2411-2422 cooperativity of p53 and SCID genes
(Nacht et al.), 2055-2066 down-modulation of apoptosis leading
to tumor progression (Naik et al.), 2105-2116
in MIS receptor-deficient mice (Mish- ina et al.), 2577-2587
role of ATM (Hawley and Friend), 2383-
2388 Review p21 in ras-tumor progression (Mis-
sero et al.), 3065-3075 p53 (Ko and Prives), 1054-1072 Re-
view Src-family kinases {Lowell and Soft-
ano), 1845-1857 Review tissue-specific inactivation of p53 tu-
mor suppression in mice (Bow- man et al.), 826--835
Tupl. See also SSN6/TUP1 interaction with histones H3 and H4
(Edmondson et al.), 1247-1259 Ty 1, targeting of integration to upstream
regions of RNA pol III-tran- scribed genes (Devine and Boeke), 620-633
Ty2, effect on expression of yeast copper transport gene (Knight et al.), 1917-1929
TyS, preferential integration into regions of silent chromatin (Zou et al.), 634-645
Tyrosine kinase receptors. See Receptor tyrosine kinases
3254 GENES & DEVELOPMENT
U1 snRNA, role in 5' splice site selec- tion (Hwang and Cohen), 338- 35O
U I snRNP interaction with
CPSF (Lutz et al.), 325-337 Mudl3p, yeast homolog of CBP20
(Colot et al.), 1699-1708 role of CBC in association with the
cap-proximal 5' splice site {Lewis et al.), 1683-1698
U2 snRNA CUS1 as suppressor of cold-sensitive
mutations {Wells et al.), 220-232 redundancy of interactions with U6 sn-
RNA {Field and Friesen), 489- 501
U2AF, function of the 35-kD subunit (Zuo and Maniatis), 1356-1368
U6 snRNA effects of U1 snRNA on 5' splice site
selection (Hwang and Cohen), 338-350
redundancy of interactions with U2 snRNA (Field and Friesen), 489- 501
U937 cells, vitamin D 3 and induced dif- ferentiation of (Liu et al.), 142- 153
UAF. See Upstream activation factor UBF. See Upstream binding factor Ubiquitin
APC-dependent degradation of Pdslp {Cohen-Fix et al.), 3081-3093
protection of E2F-1 from proteasome degradation pathway by Rb (Hofmann et al.), 2949-2959
regulation of cyclin E turnover by cdk2 (Clurman
et al.), 1979-1990 E2F degradation by Rb family pro-
teins and adenovirus transform- ing proteins (Hateboer et al.), 2960-2970
Ultraviolet cross-linking, for study of U2 snRNP proteins in spliceosome assembly (Gozani et al.), 233- 243
unc-86, coupling of cell lineage asymme- try with transcription (Baumeis- ter et al.), 1395-1410
Untranslated region, 3', role in down- regulation of LIN-14 (Ha et al.), 3041-3050
UP element, role in transcription and DNA binding by e~CTD in E. coli (Gaal et al.), 16-26
Upstream activation factor requirement for TBP in recruitment of
core factor (Steffan et al.), 2551- 2563
role in RNA pol I preinitiation com- plex formation (Keys et al.), 887-903
Upstream binding factor, comparison with UAF (Keys et al.), 887-903
Ureteric bud, defective differentiation accompanied by wild-type p53 transgene expression (Godley et al.), 836-850
USF, role of U1 snRNA in 5' splice site selection (Hwang and Cohen), 338-,350
UTR, 3'. See Untranslated region, 3'
V
V(D)J recombination. See Recombina- tion, V(D)J
v-raf, suppression of transformation by PKC-~ (Kieser et al.), 1455-1466
vab-7, role in C. elegans posterior pat- terning (Ahringer), 1120-1130
Vasa, role of interaction with Oskar in Drosophila pole plasm forma- tion (Breitwieser et al.), 2179- 2188
Vein, role in Drosophila EGF pathway (Schnepp et al.), 2302-2313
Veins, regulation of araucan and caupol- ican during Drosophila wing patterning (Gomez-Skarmeta and Modolell), 2935-2945
vestigial tail, as a hypomorphic allele of Wnt-3a (Greco et al.), 313-324
Virus-host interactions, POD organiza- tion and adenovirus replication (Doucas et al.), 196-207
Vitamin D3 induction of p21 (Liu et al.), 142-153 response element, in p21 promoter
(Liu et al.), 142-15,3
W
WAF-1. See p21 Whn, regulation of epithelial growth and
differentiation (Brissette et al.), 2212-2221
Wing, role of Delta in Drosophila devel- opment (Doherty et al.), 421- 434
Winged helix proteins, regulation of kid- ney development by BF-2 (Ha- tini et al.), 1467-1478
Wingless involvement of ~-catenin in signaling
pathway (Miller and Moon), 2527-2539 Review
role of porcupine in processing (Kad- owaki et al.), 3116-3128
wingless family role of wingless in segmentation and
specification of Drosophila me- soderm (Azpiazu et al.), 3183- 3194
vestigial tail as a hypomorphic allele of Wnt-3a (Greco et al.), 313- 324
wingless activation by Cubitus inter- ruptus (Alexandre et al.), 2003- 2013
Wings, regulation of araucan and caupolican during development in Drosophila (G6mez- Skarmeta and Modolell), 2935- 2945
Wnt proteins
LIN-17 as receptor for LIN-44 in C. elegans (Sawa et al.), 2189-2197
MyoD induction blocked by domi- nant-negative Wnt in Xenopus embryos (Hoppler et al.), 2805- 2817
signaling involvement of [3-catenin {Miller
and Moon), 2527-2539 Review role of [~-catenin and Xgsk-3 in Xe-
nopus (Yost et al.), 1443-1454 Wnt-3a, regulation of mouse axial devel-
opment (Greco et al.), 313-324 Wound healing, and keratinocyte growth
factor {Guo et al.), 165-175
X chromosome, DNA hypomethylation and gene silencing (Panning and Jaenisch), 1991-2002
Xenopus APC-dependent degradation of Pdslp
(Cohen-Fix et al.), 3081-3093 effect of dominant-negative Wnt on
embryogenesis (Hoppler et al.), 2805-2817
role of [3-catenin and Xgsk-3 (Yost et al.), 1443-1454
role of Sucl homolog Xe-p9 in cell-cy- cle control (Patra and Dunphy), 1503-151
Xer, determinants of selectivity in site- specific recombination (Blakely and Sherratt), 762-773
XerC-D system, restriction of dif site ac- tivity in E. coil (Cornet et al.), 1152-1161
Xeroderma pigmentosa, role of XPB and XPD in p53-dependent apopto- sis (Wang et al.), 1219-1232
Xgsk-3, regulation of ~-catenin {Yost et al.), 1443-1454
Xist activation of expression in response to
DNA hypomethylation (Pan- ning and Jaenisch), 1991-2002
role of DNA methylation in regulating expression of imprinted genes (Tucker et al.), 1008-1020
XPB, role in p53-dependent apoptosis {Wang et al.), 1219-1232
XPD, role in p53-dependent apoptosis (Wang et al.), 1219-1232
GENES & DEVELOPMENT 3255
Yeast, budding. See also Saccharomyces cerevisiae
activation of CUP1 in strains lacking SOD1 (Liu and Thiele), 592-603
ceramide-activated protein phos- phatase (Nickels and Broach), 382-394
CUS1 gene product role in spliceo- some assembly (Wells et al.), 220-232
determinants of late origin activation (Friedman et al.), 1595-1607
DIG1 and DIG2 as two novel MAP ki- nase targets in S. cerevisiae (Cook et al.), 2831-2848
epigenetic effects on transcription caused by mutations in a nu- clear actin-related protein (Jiang and Stillman), 604-619
function of human TOR homolog RAFT1 (Alarcon et al.), 279-288
glucose regulation of SNF1 complex interactions (Jiang and Carlson), 3105-3115
identification of Mudl3p as homolog of CBP20 (Colot et al.), 1699- 1708
in vivo function of yTAFn90 (Apone et al.), 2368-2380
preferential integration of Ty5 into re- gions of silent chromatin (Zou et al.), 634-645
redundancy of MSH3 and MSH6 in mismatch repair (Marsischky et al.), 407-420
regulation and specification of replica-
tion origins (Diffley), 2819- 2830 Review
regulation of mRNA export during stress (Saavedra et al.), 1608- 1620
single-stranded telomere end-binding protein properties of Est 1 (Virta- Pearlman et al.), 3094-3104
Spkl/Rad53 regulation by Mecl-de- pendent protein phosphoryla- tion (Sun et al.), 395--406
targeting of retrotransposon Tyl to up- stream regions of RNA pol II- transcribed genes (Devine and Boeke), 620-633
TBP role in rDNA transcription (Stef- fan et al.), 2551-2563
3'--* 5' exonuclease role in 5.8S RNA synthesis (Mitchell et al.), 502- 513
U2 snRNP proteins role in spliceo- some assembly (Gozani et al.), 233-243
Yeast, fission. See also Schizosaccharo- myces pombe
regulation of Atfl by Spcl in response to stress
{Shiozaki and Russell), 2276-- 2288
Atfl by stress-activated kinase Styl (Wilkinson et al.), 2289- 2301
S-phase onset by ORC1 homolog orpl (Grallert and Nurse), 2644- 2654
role of dmfl/rnidlin positioning of di- vision septum (Sohrmann et al.), 2707-2719
Rum l inhibition of Cdc2 kinase and interaction with Cdc18 (Jalle- palli and Kelly), 541-552
Z
ZEBRA protein, use to study the role of TFIIA-TFIID complex forma- tion in gene activation (Chi and Carey), 2540-2550
Zebrafish dino and swirl role in dorsoventral pat-
terning (Hammerschmidt et al.), 2452-2461
pescadillo and dead eye role in embry- onic development (Allende et al.), 3141-3155
PKA regulation of Hedgehog signaling in developing embryos (Ham- merschmidt et al.), 647-658
prospects for insertional mutagenesis (Schier et al.), 3077~3080 Mini- review
Zinc-finger proteins activation of patched by Cubitus in-
terruptus in response Hedgehog signaling (Alexandre et al.), 2003-2013
identification of KAP-1 as KRAB do- main corepressor (Friedman et al.), 2067-2078
as short-range transcriptional repres- sors in Drosophila (Gray and Levine), 700-710
specificity of LIM-based interactions (Arber and Caroni), 289-300
Zn finger proteins. See Zinc finger proteins ZO-1, identification of Drosophila homolog
(Takahisa et al.), 1783--1795
3256 GENES & DEVELOPMENT
Biology ofProteolysis ] A ril 23 - 27, 1997 ~,ii!!~!~ i
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Organized by: Charles S. Craik, University o f California, San Francisco
Susan Gottesman, National Cancer Institute Mark Hochstrasser, University o f Chicago
Yuri Lazebnik, Cold Spring Harbor Laboratory
Toplcs : and Session:~ Chairs : Indude ~.:
Spatial and Temporal Controls in Development
(Kathryn Anderson) Signal Transduction (Tom Maniatis)
Protein Quality Control and Chaperones
~ i c h . H a r t l )
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ii::: i i i iii:ii: i i iii!i i :! i !! i i i if: ! : ! i i i:!
CSHL particularly encourages junior scientists to present their data at the meeeting. All oral and poster
presentations will bc selected on the basis of scientific merit,
Abstract Deadl ine: January 29, 1997
Cell & Molecular Biology ofAplysia & Related Invertebrates April 16 - 20 / January 22
Regulation of Liver Gene Expression in Health and Disease April 30 - May 4 / February 5
Tyrosine Phosphorylation & Cell Signaling
May 7 - 11 / February 12 Genome M a p p i n g & Sequencing
May 14- 18 / February 19 Retroviruses
May 20 - 25 / February 26 62nd Symposium: Pattern Formation During Development
May 28 - June 2 / March 5
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and photonficrography options. Just go
where your research takes you, and so
we. To arrange a demonstration
new Olympus Provis AX-70 ~ii!
/"~ th'cr(~ope at your convenience,
i!~:~!I I t i I ~ information on the difference
I i make for you, p lease call
Reader Service No. 650
~ p u s and Research.
Seeing Eye to Eye.
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