Quinones 

The quinones represent a class of organic compounds that are formally "derived from aromatic compounds [such as benzene ornaphthalene] by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of doublebonds", resulting in "a fully conjugated cyclic dione structure". The class includes some heterocyclic compounds. A large scaleindustrial application of quinones is for the production of hydrogen peroxide. Natural quinones show a biological orpharmacological activity, and some of them show anti-tumoral activity. They embody some claims in herbal medicine. Somequinone derivatives are used for coloring substances (dyes and pigments) and oxidizing agents.

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Quinones Inhibitors & Modulators

(-)-AlkanninCat. No.: HY-N6012

(-)-Alkannin, found in , is used asAlkanna tinctoriaa food coloring. (-)-Alkannin shows anticanceractivity, arrests cell cycle, and induces

. (-)-Alkannin improves hepaticapoptosisinflammation in a Rho-kinase pathway.

Purity: 99.58%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg

(Rac)-Arnebin 1 ((Rac)-β,β-Dimethylacrylalkannin;

(Rac)-β,β-Dimethylacrylshikonin) Cat. No.: HY-N5112

(Rac)-Arnebin 1 ((Rac)-β,β-Dimethylacrylalkannin)is the racemate of β,β-Dimethylacrylalkanninand/or β,β-Dimethylacrylshikonin.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

1,2,3,7-TetramethoxyxanthoneCat. No.: HY-N4293

1,2,3,7-Tetramethoxyxanthone is a xanthoneisolated from .Polygala tenuifolia

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

1-Hydroxy-2-methylanthraquinoneCat. No.: HY-N1625

1-Hydroxy-2-methylanthraquinone exhibitsantimicrobial, antioxidant, pesticidal, andanti-inflammatory activities.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

2-Hydroxy-1-methoxyanthraquinoneCat. No.: HY-N5125

2-Hydroxy-1-methoxyanthraquinone could be isolatedfrom the stem bark of .Morinda lucida Benth(Rubiaceae) and possesses antibacterialactivity.<br/>.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

2-HydroxyanthraquinoneCat. No.: HY-W012352

2-Hydroxyanthraquinone, a natural compound,possesses antitumor and immunosuppressiveactivity.<br/>.

Purity: >98%Clinical Data: No Development ReportedSize: 500 mg

3-HydroxymorindoneCat. No.: HY-N7894

3-Hydroxymorindone is an anthraquinone and apigment.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

3-IsomangostinCat. No.: HY-N6845

3-Isomangostin, extracted from shell, is a potent MutTGarciniamangostana.L.

homologue 1 ( ) inhibitor with an valueMTH1 IC50

of 52 nM. 3-Isomangostin would be an attractivechemical tool for the development of anticanceragents.

Purity: >98%Clinical Data: No Development ReportedSize: 5 mg, 10 mg

6-HydroxyrubiadinCat. No.: HY-N2714

6-Hydroxyrubiadin, a natural anthraquinone, may bea potential therapeutic candidate for thetreatment of inflammation and inflammatorydiseases.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

8-Methyl Chrysophanol (Chrysophanol 8-methyl ether) Cat. No.: HY-N7618

8-Methyl Chrysophanol is an anthraquinone isolatedfrom the bark of .Senna macranth

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg

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AcetylshikoninCat. No.: HY-N2181

Acetylshikonin, derived from the root of, has anti-cancer andLithospermum erythrorhizon

antiinflammation activity. Acetylshikonin is anon-selective inhibitorcytochrome P450against all P450s ( values range from 1.4-4.0IC50

μM).

Purity: 98.10%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 20 mg

Aclacinomycin A hydrochloride (Aclarubicin hydrochloride) Cat. No.: HY-N2306A

Aclacinomycin A hydrochloride (Aclarubicinhydrochloride), a fluorescent molecule and thefirst described non-peptidic inhibitor showingdiscrete specificity for the CTRL(chymotrypsin-like) activity of the 20S

.proteasome

Purity: 95.16%Clinical Data: LaunchedSize: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg

AlizarinCat. No.: HY-N0563

Alizarin is a natural dye extracted from the rootsof madder plant and has been widely used as apigment in textile fabrics and paintings.

Purity: 99.17%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 500 mg, 1 g, 5 g

Aloe emodin (Rhabarberone; 3-Hydroxymethylchrysazine) Cat. No.: HY-N0189

Aloe emodin is a hydroxyanthraquinone present inAloe vera leaves, has a specific in vitro and invivo antitumor activity. IC50 value: Target: invitro: aloe-emodin treatment led to thedissociation of heat shock protein 90 (HSP90) andER α and increased ER α ubiquitination.

Purity: 98.32%Clinical Data: No Development ReportedSize: 100 mg, 500 mg

Aloe-emodin-8-O-β-D-glucopyranosideCat. No.: HY-N2451

Aloe-emodin-8-O-β-D-glucopyranoside, a compoundisolated from , is a moderateSaussrurea lappainhibitor of human protein tyrosine phosphatase

with an of 26.6 μM.1B (hPTP1B) IC50

Purity: >98%Clinical Data: No Development ReportedSize: 5 mg, 10 mg

Aloesin (Aloeresin) Cat. No.: HY-N2460

Aloesin (Aloeresin) is an active constituent ofthe herb aloe vera and displays anti-inflammatoryactivity, ultraviolet protection, andantibacterium effects. Aloesin exerts itsanticancer effect through the MAPK signalingpathway.

Purity: 99.92%Clinical Data:Size: 10 mM × 1 mL, 500 μg, 1 mg, 5 mg, 10 mg

Aloin (Aloin-A; Barbaloin-A) Cat. No.: HY-N0123

Aloin(Aloin-A; Barbaloin-A) is a natural antitumoranthraquinone glycoside with iron chelating andnon-atherogenic activities. IC50 value: Target: invitro: Aloin significantly inhibited HUVECsproliferation, migration and tube formation invitro.

Purity: 98.32%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 50 mg, 100 mg

Aloin B (Aloin-B; Isobarbaloin) Cat. No.: HY-N0886

Aloin B is one isomer of Aloin; Aloin is aphysiologically active anthraquinone present inaloe.

Purity: 99.87%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 5 mg, 10 mg

Aloin(mixture of A&B)Cat. No.: HY-N6013

Aloin (mixture of A&B) is anthraquinonederivative isolated from . Aloin (mixtureAloe veraof A&B) has diverse biological activities suchas anti-inflammatory, immunity, antidiabetic,antioxidant, antibacterial, antifungal, andantitumor activities.

Purity: 98.03%Clinical Data: No Development ReportedSize: 1 mg, 5 mg, 10 mg

Altertoxin I (Dihydroalterperylenol) Cat. No.: HY-N6724

Altertoxin I (Dihydroalterperylenol) is aquinone-type mycotoxin produced by Alternaria

fungi, which is mutagenic and cytotoxic,alternataand can weakly disrupts metabolic communication.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

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AnthraquinoneCat. No.: HY-N0354

Anthraquinone is used as a precursor for dyeformation.

Purity: 98.14%Clinical Data: No Development ReportedSize: 100 mg

Anthraquinone-2-carboxylic acidCat. No.: HY-W031757

Anthraquinone-2-carboxylic acid is a majoranthraquinone isolated from , withBrazilian taheeboanti-inflammatory activity and antinociceptive.

Purity: ≥97.0%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 250 mg, 500 mg

Aurantio-obtusinCat. No.: HY-N0261

Aurantio-obtusin is an anthraquinone isolated from, with anti-Inflammatory,Semen Cassiae

anti-oxidative, anti-coagulating andanti-hypertension activities.

Purity: 99.45%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 20 mg

BuparvaquoneCat. No.: HY-17581

Buparvaquone is a hydroxynaphthoquinoneantiprotozoal drug related to parvaquone andatovaquone.

Purity: 99.82%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg

CasanthranolCat. No.: HY-B2134

Casanthranol is a concentrated mixture ofanthranol glycosides from cascara sagrada (driedbark of ) and used as a laxative inRhamnus p.constipation and various medical conditions,stimulant laxative Casanthranol encourages bowelmovements by acting on the intestinal wall…

Purity: >98%Clinical Data: LaunchedSize: 500 mg

ChrysoobtusinCat. No.: HY-133860

Chrysoobtusin is an anthraquinone derivativeisolated from Semen Cassiae. Semen Cassiae haslong been used to protect liver, brighten eyes,and relieve constipation.

Purity: 99.39%Clinical Data: No Development ReportedSize: 5 mg

Chrysophanol (Chrysophanic acid) Cat. No.: HY-13595

Chrysophanol (Chrysophanic acid) is a naturalanthraquinone, which inhibits EGF-inducedphosphorylation of and suppresses activationEGFRof and / .AKT mTOR p70S6K

Purity: 99.73%Clinical Data: No Development ReportedSize: 50 mg, 100 mg

Chrysophanol 8-O-glucosideCat. No.: HY-N2395

Chrysophanol 8-O-glucoside, from the roots of, shows moderate inhibitionRumex acetosa elastase

activity.

Purity: >98%Clinical Data: No Development ReportedSize: 5 mg, 10 mg

Coenzyme Q10 (CoQ10; Ubiquinone-10) Cat. No.: HY-N0111

Coenzyme Q10 is an essential cofactor of theelectron transport chain and a potent antioxidantagent.

Purity: ≥98.0%Clinical Data: LaunchedSize: 100 mg, 200 mg, 500 mg, 1 g, 5 g

Coenzyme Q9 (Ubiquinone Q9; CoQ9; Ubiquinone 9) Cat. No.: HY-101415

Coenzyme Q9 (Ubiquinone Q9), the major form ofubiquinone in rodents, is an amphipathic molecularcomponent of the electron transport chain thatfunctions as an endogenous antioxidant. CoenzymeQ9 attenuates the diabetes-induced decreases inantioxidant defense mechanisms.

Purity: ≥98.0%Clinical Data: No Development ReportedSize: 1 mg, 5 mg, 10 mg

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Cryptotanshinone (Cryptotanshinon; Tanshinone c) Cat. No.: HY-N0174

Cryptotanshinone is a natural compound extractedfrom the root of Bunge thatSalvia miltiorrhizashows antitumor activities. Cryptotanshinoneinhibits with an of 4.6 μM.STAT3 IC50

Purity: 98.17%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 10 mg, 50 mg

DamnacanthalCat. No.: HY-108485

Damnacanthal is an anthraquinone isolated from theroot of . Damnacanthal is aMorinda citrifoliahighly potent, selective inhibitor of p56lck

activity.tyrosine kinase

Purity: ≥98.0%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

Danshenxinkun ACat. No.: HY-N3680

Danshenxinkun A is a natural compound that couldbe isolated from Tanshen and is used in the studyfor heart diseases.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg

Danshenxinkun BCat. No.: HY-N6922

Danshenxinkun B is an antioxidative component oftanshen (Salvia miltiorhiza Bung) .

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

Danthron (Dantron; Chrysazin; 1,8-Dihydroxyanthraquinone) Cat. No.: HY-B0923

Danthron is a natural product extracted from thetraditional Chinese medicine . Danthronrhubarbfunctions in regulating glucose and lipidmetabolism by activating .AMPK

Purity: 98.70%Clinical Data: LaunchedSize: 10 mM × 1 mL, 100 mg

Daunorubicin (Daunomycin; RP 13057; Rubidomycin) Cat. No.: HY-13062A

Daunorubicin (Daunomycin; RP 13057; Rubidomycin)is a inhibitor with potenttopoisomerase IIantineoplastic activities. Daunorubicin(Daunomycin; RP 13057; Rubidomycin) inhibits DNA

in sensitive and resistantand RNA synthesisEhrlich ascites tumor cells.

Purity: >98%Clinical Data: LaunchedSize: 1 mg, 5 mg

Daunorubicin hydrochloride (Daunomycin hydrochloride; RP

13057 hydrochloride; Rubidomycin hydrochloride) Cat. No.: HY-13062

Daunorubicin (Daunomycin) hydrochloride is a inhibitor with potenttopoisomerase II

antineoplastic activities. Daunorubicinhydrochloride inhibits inDNA and RNA synthesissensitive and resistant Ehrlich ascites tumorcells.

Purity: 99.37%Clinical Data: LaunchedSize: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg, 200 mg, 500 mg

Dehydrobruceine ACat. No.: HY-N8257

Dehydrobruceine A is a low potent antitrypanosomalagent, with an of 88.5 nM for IC50 Plasmodium

.falciparum

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

DeoxyshikoninCat. No.: HY-N2187

Deoxyshikonin is isolated from Lithospermum Sieb with antitumor activity.erythrorhizon

Purity: 99.96%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 5 mg

Diacerein (Diacerhein; Diacetylrhein) Cat. No.: HY-N0283

Diacerein (Diacerhein), a interleukin-1 betainhibitor, is a slow-acting medicine of the classanthraquinone used to treat joint diseases.

Purity: 98.78%Clinical Data: LaunchedSize: 10 mM × 1 mL, 50 mg, 100 mg

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DihydroevocarpineCat. No.: HY-N2517

Dihydroevocarpine induces cytotoxicity in acutemyeloid leukemia via suppressing the mTORC1/2activity.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

Dihydroisotanshinone ICat. No.: HY-B1919

Dihydroisotanshinone I, a bioactive compoundpresent in danshen, can inhibit the migration ofboth androgen-dependent and androgen-independentprostate cancer cells. Dihydroisotanshinone I alsoinduces and in these lungapoptosis ferroptosiscancer cells.

Purity: 99.52%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg

Dihydrotanshinone ICat. No.: HY-N0360

Dihydrotanshinone I is a natural compoundextracted from which hasSalvia miltiorrhiza Bungebeen widely used for treating cardiovasculardiseases. Dihydrotanshinone I exhibitsentry-blocking effect for MERS-CoV.

Purity: 99.22%Clinical Data: No Development ReportedSize: 10 mg, 25 mg, 50 mg

Doxorubicin (Hydroxydaunorubicin) Cat. No.: HY-15142A

Doxorubicin (Hydroxydaunorubicin), a cytotoxicanthracycline antibiotic, is an anti-cancerchemotherapy agent. Doxorubicin inhibits

with an of 2.67 μM, thustopoisomerase II IC50

stopping DNA replication.

Purity: >98%Clinical Data: LaunchedSize: 1 mg, 5 mg

Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride) Cat. No.: HY-15142

Doxorubicin (Hydroxydaunorubicin) hydrochloride, acytotoxic anthracycline antibiotic, is ananti-cancer chemotherapy agent. Doxorubicinhydrochloride is a potent human DNA topoisomerase and inhibitor with s ofI topoisomerase II IC50

0.8 μM and 2.67 μM, respectively.

Purity: 99.47%Clinical Data: LaunchedSize: 10 mM × 1 mL, 50 mg, 100 mg, 200 mg, 500 mg, 1 g

Embelin (Embelic acid; Emberine; NSC 91874) Cat. No.: HY-17473

Embelin (Embelic acid), a potent, nonpeptidic XIAPinhibitor ( =4.1 μM), inhibits cell growth,IC50

induces , and activates caspase-9 inapoptosisprostate cancer cells with high levels of XIAP.

Purity: 98.75%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 10 mg, 50 mg

Emodin (Frangula emodin) Cat. No.: HY-14393

Emodin (Frangula emodin), an anthraquinonederivative, is an anti- compound. EmodinSARS-CoVblocks the SARS coronavirus spike protein andangiotensin-converting enzyme 2 (ACE2)interaction. Emodin inhibits ( ).casein kinase-2 CK2Anti-inflammatory and anticancer effects.

Purity: 99.39%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 50 mg, 100 mg, 200 mg

Emodin-1-O-β-D-glucopyranosideCat. No.: HY-N2394

Emodin-1-O-β-D-glucopyranoside, isolated frommedicinal plant Polygonum cuspidatum Sieb. &Zucc, is a potent and noncompetitive bacterial

inhibitor with an ofneuraminidase (BNA) IC50

0.85 μM.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg, 10 mg

Emodin-1-O-β-gentiobiosideCat. No.: HY-N8143

Emodin-1-O-β-gentiobioside is an anthraquinone.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

EmodinanthroneCat. No.: HY-N9362

Emodinanthrone, an anthraquinone, is a sprecursorof Emodin (HY-14393) with antibiotic activity.Emodinanthrone inhibits respiration-driven solutetransport at micromolar concentrations in membranevesicles of .Escherichia coli

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

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Fuscaxanthone CCat. No.: HY-N6247

Fuscaxanthone C is an xanthone isolated from thestem bark of .Garcinia fusca

Purity: >98%Clinical Data: No Development ReportedSize: 5 mg

Gambogellic acidCat. No.: HY-N4304

Gambogellic acid is an xanthone isolated from theprocessed gamboge, with antitumor activity.

Purity: >98%Clinical Data: No Development ReportedSize: 5 mg, 10 mg

GeldanamycinCat. No.: HY-15230

Geldanamycin is a inhibitor withHsp90antimicrobial activity against many Gram-positiveand some Gram-negative bacteria. Geldanamycin hasanti-influenza virus activities.H5N1

Purity: 99.78%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 5 mg, 10 mg

Huanglongmycin NCat. No.: HY-N10115

Huanglongmycin N is a DNA topoisomerase Iinhibitor ( = 14 μM).EC50

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

IsobutylshikoninCat. No.: HY-N2592

Isobutylshikonin is a kind of shikonin pigmentsfrom hairy root culture of Lithospermum

.canescens

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

IsocryptotanshinoneCat. No.: HY-N6651

Isocryptotanshinone is a potent signal transducerand activator of transcription 3 ( ) andSTAT3protein tyrosine phosphatase 1B inhibitor,PTP1Bwith an of 56.1 μM for PTP1B.IC50

Purity: ≥98.0%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

IsoeleutherinCat. No.: HY-129055

Isoeleutherin is a naphthopyran derivativeisolated from withE. americana Merr. Et Heyneanti- , anti-viral, and anti-tumor activities.fungalIsoeleutherin plays an important role in selectivemodulation of T helper cell-mediated immuneresponses.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg

Juglone (5-Hydroxy-1,4-naphthalenedione) Cat. No.: HY-N6949

Juglone is a yellow pigment found in black walnut( ). Juglone also shows Juglans regia antimicrobialactivity.

Purity: ≥97.0%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 20 mg

LapacholCat. No.: HY-N6961

Lapachol is a naphthoquinone that was firstisolated from (Bignoniaceae).Tabebuia avellanedae

Purity: ≥97.0%Clinical Data: No Development ReportedSize: 10 mg, 50 mg, 100 mg

LawsoneCat. No.: HY-N2493

Lawsone is a naphthoquinone dye isolated fromleaves of that showsLawsonia inermisantimicrobial and antioxidant activity.

Purity: ≥95.0%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 500 mg

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Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone) Cat. No.: HY-N7116

Lawsone methyl ether(2-Methoxy-1,4-naphthoquinone), isolated from

. and ,Impatiens balsamina L Swertia calycinaexhibits potent antifungal and antibacterialactivities.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

Lucidin 3-O-glucosideCat. No.: HY-N7975

Lucidin 3-O-glucoside is an anthraquinoneanalogue.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

Menadione (Vitamin K3) Cat. No.: HY-B0332

Menadione, a synthetic naphthoquinone, can beconverted to active vitamin K2 in vivo. Target:Others Menadione (Vitamin K3) is a syntheticanalogue of of 1,4-naphthoquinone with a methylgroup in the 2-position.

Purity: 98.07%Clinical Data: LaunchedSize: 10 mM × 1 mL, 500 mg, 1 g

MiltironeCat. No.: HY-N1951

Miltirone is a natural compound present in theroot of . Miltirone is aSalvia miltiorrhizacentral partial agonist,benzodiazepine receptorwith an of 0.3 μM.IC50

Purity: 99.74%Clinical Data: No Development ReportedSize: 5 mg

NorswertianolinCat. No.: HY-N6617

Norswertianolin acts as a activator and isCSEisolated from G. acuta. Norswertianolin may be apotential agent for cardiovascular diseases.

Purity: 99.27%Clinical Data: No Development ReportedSize: 5 mg, 10 mg

ObtusifolinCat. No.: HY-N2098

Obtusifolin, isolated from the seeds of Cassia, regulates the gene expression andobtusifolia

production of MUC5AC mucin in airway epithelialcells via inhibiting pathway.NF-kB

Purity: 99.80%Clinical Data: No Development ReportedSize: 5 mg, 10 mg

Ochromycinone ((Rac)-STA-21) Cat. No.: HY-18061

Ochromycinone ((Rac)-STA-21) is a naturalantibiotic and a inhibitor. OchromycinoneSTAT3can inhibits DNA binding activity, STAT3 STAT3dimerization. Ochromycinone has anticancer andantimicrobial activity.

Purity: 98.29%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Phloretin (NSC 407292; RJC 02792) Cat. No.: HY-N0142

Phloretin (NSC 407292; RJC 02792) is a flavonoidextracted from Prunus mandshurica, hasanti-inflammatory activities. Phloridzin is aspecific, competitive and orally active inhibitorof in thesodium/glucose cotransportersintestine (SGLT1) and kidney (SGLT2).

Purity: 99.78%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 250 mg, 500 mg

Physcion (Parietin; Rheochrysidin) Cat. No.: HY-N0108

Physcion (Parietin) is an anthraquinone isolatedfrom traditional Chinese medicine Radix et RhizomaRhei, acts as an inhibitor of 6-phosphogluconate

, with an and a of 38.5 μMdehydrogenase IC50 Kd

and 26.0 μM, respectively.

Purity: 99.10%Clinical Data: No Development ReportedSize: 10 mg, 25 mg, 50 mg, 100 mg

Plumbagin (2-Methyljuglone) Cat. No.: HY-N1497

Plumbagin (2-Methyljuglone) is a naphthoquinoneisolated from , exhibitsPlumbago zeylanica Lanticancer and antiproliferative activities.

Purity: 99.65%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 50 mg

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Polygalaxanthone XICat. No.: HY-N6803

Polygalaxanthone XI, a xanthone glycoside isolatedfrom the cortexes of , can bePolygala tenuifoliaused in the study of expectorant, sedative, andtranquilizing agent.

Purity: >98%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 20 mg

ProtohypericinCat. No.: HY-N4139

Protohypericin is a naturally occurringnaphthodianthrone derived from plant Hypericum

. Radioiodinated protohypericin isperforatumused in Tumor necrosis targeted radiotherapy.

Purity: >98%Clinical Data: No Development ReportedSize: 5 mg, 10 mg

PseudohypericinCat. No.: HY-N0685

Pseudohypericin and its congener Hypericin are themajor hydroxylated phenanthroperylenedionespresent in Hypericum species. Pseudohypericinshows anti-HIV activity.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

PurpurinCat. No.: HY-N0571

Purpurin is a natural anthraquinone compound from L.. Purpurin hasRubia tinctorum

antidepressant-like effects.

Purity: 98.26%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 100 mg

Pyrroloquinoline quinone (PQQ; Methoxatin) Cat. No.: HY-100196

Pyrroloquinoline quinone (PQQ), a redox co-factor,is an anionic, redox-cycling orthoquinone.Pyrroloquinoline quinone is isolated from culturesof methylotropic bacteria and tissues of mammals.Pyrroloquinoline quinone is an essential nutrientfor mammals and is important for immune function.

Purity: 99.53%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Pyrroloquinoline quinone disodium salt (PQQ disodium salt; Methoxatin disodium salt) Cat. No.: HY-100196A

Pyrroloquinoline quinone disodium salt, a redoxco-factor, is an anionic, redox-cyclingorthoquinone. Pyrroloquinoline quinone disodiumsalt is isolated from cultures of methylotropicbacteria and tissues of mammals.

Purity: ≥98.0%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg

QuestinCat. No.: HY-137990

Questin is an antibacterial agent isolated frommarine Aspergillus flavipes. Questin exhibitsantibacterial activity against , V. harveyi V.

, , and anguillarum V. cholerae V. with MIC values of 31.25 µg/mL,parahemolyticus

62.5 µg/mL, 62.5 µg/mL, and 125 µg/mL.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

Quinizarin (1,4-Dihydroxyanthraquinone) Cat. No.: HY-D0226

Quinizarin (1,4-Dihydroxyanthraquinone), a part ofthe anticancer agents such as Doxorubicin,Daunorubicin, and Adriamycin, interacts with DNAby intercalating mode ( =86.1 μM).Kd

Purity: ≥98.0%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 500 mg

Rhein (Rheic Acid; Rhubarb yellow; Monorhein) Cat. No.: HY-N0105

Rhein is a lipophilic anthraquinone extensivelyfound in medicinal herbs, and has manypharmacological effects, includingepatoprotective, nephroprotective,anti-inflammatory, antioxidant, anticancer, andantimicrobial activities.

Purity: 99.73%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 100 mg, 200 mg, 500 mg

Rhein 8-Glucoside (Rhein 8-O-β-D-Glucopyranoside) Cat. No.: HY-N6082

Rhein 8-Glucoside (Rhein 8-O-β-D-Glucopyranoside)is an anthraquinone glycoside that has been foundin rhubarb. Purgative activity.

Purity: >98%Clinical Data: No Development ReportedSize: 5 mg, 10 mg

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Rifamycin SCat. No.: HY-125365

Rifamycin S, a quinone, is an antibiotic against (including ).Gram-positive bacteria MRSA

Rifamycin S is the oxidized forms of a reversibleoxidation-reduction system involving twoelectrons.

Purity: 99.22%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 50 mg, 100 mg

RubiadinCat. No.: HY-N0444

Rubiadin is a dihydroxy anthraquinone isolatedfrom . Rubiadin has a potentRubia cordifolia

activity.antixidant

Purity: >98%Clinical Data: No Development ReportedSize: 5 mg, 10 mg

Rubiadin-1-methyl etherCat. No.: HY-N1956

Rubiadin-1-methyl ether is a natural anthraquinoneisolated from How, andMorinda officinalisinhibits osteoclastic bone resorption viainhibition on the phosphorylation of NF-κB p65and the degradation of IκBα as well as decrease inthe nuclear translocation of p65.

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

Sennoside ACat. No.: HY-N0365

Sennoside A is an anthraquinone glycoside, foundin large quantities in leaves and pods of Senna( ). Sennoside A is a Cassia angustifolia HIV-1inhibitor effective on HIV-1 replication.

Purity: 99.71%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg

Sennoside BCat. No.: HY-N0366

Sennoside B is an anthraquinone glycoside, foundin large quantities in leaves and pods of Senna( ). Sennoside B can inhibitCassia angustifoliaPDGF-stimulated cell proliferation by binding toPDGF-BB and its receptor and by down-regulatingthe PDGFR-beta signaling pathway.

Purity: 99.44%Clinical Data: No Development ReportedSize: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg

Sennoside CCat. No.: HY-N1972

Sennoside C is an anthraquinone glycoside, foundin leaves and pods of Senna ( ).Cassia angustifolia

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

Sennoside DCat. No.: HY-N1973

Sennoside D is an anthraquinone glycoside, foundin leaves and pods of Senna ( ).Cassia angustifolia

Purity: >98%Clinical Data: No Development ReportedSize: 1 mg, 5 mg

Shikonin (C.I. 75535; Isoarnebin 4) Cat. No.: HY-N0822

Shikonin is a major component of a Chinese herbalmedicine named zicao. Shikonin is a potent

inhibitor with an TMEM16A chloride channel IC50

of 6.5 μM. Shikonin is a specific pyruvate kinase inhibitor and can also inhibit M2 (PKM2) TNF-α

and pathway.NF-κB

Purity: 99.80%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Tanshinone IIA (Dan Shen ketone) Cat. No.: HY-N0135

Tanshinone IIA (Tan IIA) is one of the maincompositions in the root of red-rooted salvia.Tanshinone IIA may suppress angiogenesis bytargeting the protein kinase domains of

/ .VEGF VEGFR2

Purity: 99.74%Clinical Data: Phase 4Size: 10 mg, 25 mg, 50 mg

Tanshinone IIA sulfonate sodium (Sodium Tanshinone IIA

sulfonate; Tanshinone IIA sodium sulfonate) Cat. No.: HY-N1370

Tanshinone IIA sulfonate (sodium) is a derivativeof tanshinone IIA, which acts as an inhibitor ofstore-operated Ca entry (SOCE), and is used to2+

treat cardiovascular disorders.

Purity: ≥98.0%Clinical Data: LaunchedSize: 10 mg, 25 mg

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ThymoquinoneCat. No.: HY-D0803

Thymoquinone is a nature product isolated from N.. Thymoquinone possess antioxidant,sativa

anti-inflammatory, anti-cancer, antitumoractivities and hepatoprotective properties.

Purity: ≥98.0%Clinical Data: Phase 2Size: 10 mM × 1 mL, 100 mg

Vitamin K1 (Phylloquinone; Phytomenadione) Cat. No.: HY-N0684

Vitamin K1 a naturally occurring vitamin requiredfor blood coagulation and bone and vascularmetabolism.

Purity: ≥98.0%Clinical Data: LaunchedSize: 10 mM × 1 mL, 500 mg, 1 g, 5 g

Xanthopurpurin (Purpuroxanthin) Cat. No.: HY-N7619

Xanthopurpurin, an anthraquinone glycoside,isolated from the roots of , shows mainlyRubia akanestrong inhibition of collagen-induced plateletaggregation.

Purity: 97.68%Clinical Data: No Development ReportedSize: 1 mg

β,β-Dimethylacrylalkannin (Arnebin 1) Cat. No.: HY-N5112A

β,β-Dimethylacrylalkannin (Arnebin 1) is anapthoquinone isolated from Arnebia nobilisReichb.f, increases collagen and involucrincontent in skin cells.

Purity: 98.03%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 20 mg

β,β-Dimethylacrylshikonin (Isoarnebin I) Cat. No.: HY-N5112B

β,β-Dimethylacrylshikonin (Isoarnebin I) is anaphthoquinone derivative isolated from Arnebia

, promotes angiogenesis by inducing eNOS,nobilisVEGF and HIF-1α expression through thePI3K-dependent pathway.β,β-Dimethylacrylshikoninhas anti-tumor activity.

Purity: 99.64%Clinical Data: No Development ReportedSize: 5 mg, 10 mg, 20 mg

β-Lapachone (ARQ-501; NSC-26326) Cat. No.: HY-13555

β-Lapachone (ARQ-501;NSC-26326) is a naturallyoccurring O-naphthoquinone, acts as a

inhibitor, and induces apoptosistopoisomerase Iby inhibiting cell cycle progression.

Purity: 99.85%Clinical Data: Phase 2Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg

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