Practice teaching coursein IVF: A guided journeythrough a modern centreRome, Italy

PRACTICE TEACHING COURSESCIENTIFIC PROGRAMME

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The course held on the following dates:

9 -10 June 2016

22-23 September 2016

OverviewThis teaching course is aimed at providing clinicians, embryologistand basic scientists working in assisted reproductive medicine, anopportunity to focus and discuss some of the most attractive advancesin the field of Assisted Reproductive Technology (ART). The course willfocus on controlled ovarian stimulation, on new laboratory techniquesand equipment for optimization of IVF procedures, as well as ongenetics in ART. Correct counseling and choosing the appropriateIVF treatment for each patient requires constant updating anddevelopment of new technologies. For this reason, participants willimprove their clinical and embryological knowledge of an IVF cycle byparticipating to an IVF unit tour guided by a dedicated tutor. Theprogramme is designed to allow different experiences to be sharedthrough a mix of biological and clinical lecture as well as clinical caseson controversial topics. Interactive “open discussion” moments andposing of “burning” questions will be most welcome to give thepossibility to exchange views.

Learning objectivesBy attending this course, participants will be able to:

• Recognise the crucial steps in the correct management of aninfertile couple

• Analyse the organisation of an IVF unit

• Evaluate the role of the new IVF technologies to improve embryoevaluation and selection

• Understand the importance of genetics in IVF and the role of pre-implantation genetic diagnosis in the modern embryology

• Recognise factors that can influence the success in assistedreproductive technology (ART)

Practice teaching course in IVF: A guided journey through a moderncentre

Target audienceThis course is designed for a small group of 12 doctors composedof 6 young clinicians or physicians paired with 6 embryologists -preferably drawn from the same IVF centres - so as to applytechniques to their daily clinical practice.

ChairsLaura RienziBiologist, Laboratory Director of G.EN.E.R.A. Center for Reproductive Medicine

Filippo Maria UbaldiGynecologist, Clinical Director of G.EN.E.R.A. Center for Reproductive Medicine

EXCEMED designed this programme in partnership with:

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CME ProviderEXCEMED is a non profit foundation dedicated, since the last fourdecades, to the development of high-quality medical educationprogramme all over the world.EXCEMED adheres to the guidelines and standards of the EuropeanAccreditation Council for Continuing Medical Education (EACCME®)which states that continuing medical education must be balanced,independent, objective, and scientifically rigorous.

Continuing medical educationEXCEMED (www.excemed.org) is accredited by the EuropeanAccreditation Council for Continuing Medical Education (EACCME®)to provide the following CME activity for medical specialists. TheEACCME® is an institution of the European Union of MedicalSpecialists (UEMS), www.uems.netThe CME course “Practice teaching course in IVF: A guided journeythrough a modern centre” held in Rome, Italy, is designated for amaximum of 11 (eleven) hours of European CME credits (ECMEC).Each medical specialist should claim only those credits that he/sheactually spent in the educational activity. EACCME® credits arerecognized by the American Medical Association (AMA) towards thePhysician's Recognition Award (PRA). To convert EACCME® credit toAMA PRA category 1 credit, please contact the AMA.

EXCEMED adheres to the principles of the Good CME Practice group(gCMEp).

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G.EN.E.R.A. Center for Reproductive Medicine

Antonio CapalboBiotechnologist Specialist in Medical GeneticsDirector of GENETYX Molecular Biology Laboratory

Danilo CimadomoMolecular Biologist, GENETYX Molecular Biology laboratory

Silvia ColamariaGynecologist, Responsible for PMA Treatment

Laura RienziBiologist, Laboratory Director

Filippo Maria UbaldiGynecologist, Clinical Director

Alberto VaiarelliGynecologist, Responsible for PMA Treatment

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Faculty

Programme

Day 1 - Thursday

Meeting point:

G.EN.E.R.A. Training CenterVia Giuseppe de Notaris, 1E - 00197 Rome, Italy

09.00 Welcome presentationL. Rienzi (Italy) - F.M. Ubaldi (Italy)

09.15 Clinical work-up Overview on clinical state of ART: strategies to improveefficiency in IVF treatment F.M. Ubaldi (Italy)

• Personalization of controlled ovarian stimulation

• New insights in ovarian exploitation

• How to reduce risks in ART

10.45 Coffee break

11.15 Laboratory technologiesOverview of the modern IVF Lab: Lab technologies neededto maximize success L. Rienzi (Italy)

• Embryo culture

• Embryo assesment today

• Oocyte and embryo vitrification: current state

12.45 Interactive discussion

13.00 Lunch

Clinical workup and laboratory technologies Session I

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14.00 Parallel sessionsA. Capalbo, D. Cimadomo, S. Colamaria, A. Vaiarelli (Italy)

15.00 Coffee break

15.30 Parallel sessionsA. Capalbo, D. Cimadomo, S. Colamaria, A. Vaiarelli (Italy)

16.30 Parallel sessionsA. Capalbo, D. Cimadomo, S. Colamaria, A. Vaiarelli (Italy)

17.30 End of the first day

Clinical cases and clinic tour Session II

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Group A

IVF unit tour

Group B

Clinical cases

Group C

Clinical cases

Group A

Clinical cases

Group B

IVF unit tour

Group C

Clinical cases

Group A

Clinical cases

Group B

Clinical cases

Group C

IVF unit tour

IVF unit tourVisit to the GENERA Centre’s Operating Theatre and Embryo Lab.Visit to the unit will be planned according to the treatments in programmeduring those days. Participants will visit the following activities:• Oocyte retrieval• Oocytes insemination• Embryos and blastocyst evaluation• Blastocyts stage biopsy for PGD PGS• Embryo transfer procedure• Oocyte and embryo cryopreservation• Testicular sperm extraction

Clinical casesThere will be description and interactive discussion concerning real cases.Participants are also invited to send their own clinical cases in advance sothat they can be studied and discussed with the experts during the clinicalcases sessions.

Day 2 - Friday

Meeting point:

G.EN.E.R.A. Training CenterVia Giuseppe de Notaris, 1E - 00197 Rome, Italy

09.15 Genetics in ART A. Capalbo (Italy) - D. Cimadomo (Italy)

• Genetic screening in infertile populations

• Pre-implantation genetic diagnosis for monogenic and chromosomal abnormalities

• Pre-implant genetic diagnosis for aneuploidy testing

• Noninvasive pre natal testing

10.45 Coffee break

11.15 Parallel sessionsD. Cimadomo (Italy) - A. Vaiarelli (Italy)

12.15 Video session

13.15 Discussion

13.45 Concluding remarks

14.00 End of the course

Closing lunch

Genetics in ARTSession III

Clinical cases and video session Session IV

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Group A

Clinical cases

Group B

Clinical cases

Group C

Clinical cases

General information

VenueThis live educational course takes place at the:

G.EN.E.R.A. Center for Reproductive Medicine, Valle Giulia ClinicVia Giuseppe de Notaris, 200197 Rome, Italy

and

G.EN.E.R.A. Training CenterVia Giuseppe de Notaris, 1E00197 Rome, Italy

LanguageThe official language of this course is English.

CME ProviderEXCEMED - Excellence in Medical Education

Senior Programme Manager: Chloé Xilinas T +39 06 420413 505 - F +39 06 420413 677chloe.xilinas@excemed.org

Medical Advisor: Alberto Vaiarellialberto.vaiarelli@gmail.com

For any logistic support please contact:

Meridiano Congress International Congress Manager: Andrea GruppusoT +39 06 88595 241 - F +39 06 88595 234 andrea.gruppuso@meridiano.it

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Disclosure of faculty relationships

EXCEMED adheres to guidelines of the European AccreditationCouncil for Continuing Medical Education (EACCME®) and all otherprofessional organisations, as applicable, which state thatprogrammes awarding continuing education credits must bebalanced, independent, objective, and scientifically rigorous.Investigative and other uses for pharmaceutical agents, medicaldevices, and other products (other than those uses indicated inapproved product labeling/package insert for the product) may bepresented in the programme (which may reflect clinical experience,the professional literature or other clinical sources known to thepresenter). We ask all presenters to provide participants withinformation about relationships with pharmaceutical or medicalequipment companies that may have relevance to their lectures. Thispolicy is not intended to exclude faculty who have relationships withsuch companies; it is only intended to inform participants of anypotential conflicts so that participants may form their ownjudgements, based on full disclosure of the facts. Further, all opinionsand recommendations presented during the programme and allprogramme-related materials neither imply an endorsement nor arecommendation on the part of EXCEMED. All presentationsrepresent solely the independent views of the presenters/authors.

The following faculty provided information regarding significantcommercial relationships and/or discussions of investigational ornon-EMEA/FDA approved (off-label) uses of drugs:

Antonio Capalbo Declared no potential conflict of interest.

Danilo Cimadomo Declared no potential conflict of interest.

Silvia Colamaria Declared no potential conflict of interest.

Laura Rienzi Declared no potential conflict of interest.

Filippo Maria Ubaldi Declared no potential conflict of interest.

Alberto Vaiarelli Declared no potential conflict of interest.

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All EXCEMED programmes are organized solely to promote the exchangeand dissemination of scientific and medical information. No forms ofpromotional activities are permitted. There may be presentations discussinginvestigational uses of various products. These views are the responsibility ofthe named speakers, and do not represent an endorsement orrecommendation on the part of EXCEMED. This programme is madepossible thanks to an educational grant received from Merck KGaA,Darmstadt, Germany.

EXCEMED - Excellence in Medical EducationHeadquarters14, Rue du Rhône - 1204 Geneva, SwitzerlandRepresentative OfficeSalita di San Nicola da Tolentino 1/b - 00187 Rome, ItalyT +39 06 420413 1 - F +39 06 420413 677

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