Practice teaching coursein IVF: A guided journeythrough a modern centre22-23 September 2016Rome, Italy

PRACTICE TEACHING COURSESCIENTIFIC PROGRAMME

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OverviewThis teaching course is aimed at providing clinicians, embryologistand basic scientists working in assisted reproductive medicine, anopportunity to focus and discuss some of the most attractive advancesin the field of Assisted Reproductive Technology (ART). The course willfocus on controlled ovarian stimulation, on new laboratory techniquesand equipment for optimization of IVF procedures, as well as ongenetics in ART. Correct counseling and choosing the appropriateIVF treatment for each patient requires constant updating anddevelopment of new technologies. For this reason, participants willimprove their clinical and embryological knowledge of an IVF cycle byparticipating to an IVF unit tour guided by a dedicated tutor. Theprogramme is designed to allow different experiences to be sharedthrough a mix of biological and clinical lecture as well as clinical caseson controversial topics. Interactive “open discussion” moments andposing of “burning” questions will be most welcome to give thepossibility to exchange views.

Learning objectivesBy attending this course, participants will be able to:

• Recognise the crucial steps in the correct management of aninfertile couple

• Analyse the organisation of an IVF unit

• Evaluate the role of the new IVF technologies to improve embryoevaluation and selection

• Understand the importance of genetics in IVF and the role of pre-implantation genetic diagnosis in the modern embryology

• Recognise factors that can influence the success in assistedreproductive technology (ART)

Practice teaching course in IVF: A guided journey through a moderncentre

Target audienceThis course is designed for a small group of doctors composed ofclinicians or physicians and embryologists - preferably drawn fromthe same IVF centres - so as to apply techniques to their daily clinicalpractice.

ChairsLaura RienziBiologist, Laboratory Director of G.EN.E.R.A. Center for Reproductive Medicine

Filippo Maria UbaldiGynecologist, Clinical Director of G.EN.E.R.A. Center for Reproductive Medicine

EXCEMED designed this programme in partnership with:

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CME ProviderEXCEMED is a non profit foundation dedicated, since the last fourdecades, to the development of high-quality medical educationprogrammes all over the world.EXCEMED adheres to the guidelines and standards of the EuropeanAccreditation Council for Continuing Medical Education (EACCME®)which states that continuing medical education must be balanced,independent, objective, and scientifically rigorous.

Continuing medical educationEXCEMED (www.excemed.org) is accredited by the EuropeanAccreditation Council for Continuing Medical Education (EACCME®)to provide the following CME activity for medical specialists. TheEACCME® is an institution of the European Union of MedicalSpecialists (UEMS), www.uems.netThe CME course “Practice teaching course in IVF: A guided journeythrough a modern centre” held in Rome, Italy, is designated for amaximum of 9 (nine) hours of European CME credits (ECMEC). Eachmedical specialist should claim only those credits that he/sheactually spent in the educational activity. EACCME® credits arerecognized by the American Medical Association (AMA) towards thePhysician's Recognition Award (PRA). To convert EACCME® credit toAMA PRA category 1 credit, please contact the AMA.

EXCEMED adheres to the principles of the Good CME Practice group(gCMEp).

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G.EN.E.R.A. Center for Reproductive Medicine

Antonio CapalboBiotechnologist Specialist in Medical GeneticsDirector of GENETYX Molecular Biology Laboratory

Danilo CimadomoMolecular Biologist, GENETYX Molecular Biology laboratory

Silvia ColamariaGynecologist, Responsible for PMA Treatment

Laura RienziBiologist, Laboratory Director

Filippo Maria UbaldiGynecologist, Clinical Director

Alberto VaiarelliGynecologist, Responsible for PMA Treatment

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Faculty

Programme

Thursday, 22 September

Meeting point:

G.EN.E.R.A. Training CenterVia Giuseppe de Notaris, 1E - 00197 Rome, Italy

09.00 Welcome presentationF.M. Ubaldi (Italy)

09.05 Clinical work-up Overview on clinical state of ART: strategies to improveefficiency in IVF treatment F.M. Ubaldi (Italy)

• Personalization of controlled ovarian stimulation

• New insights in ovarian exploitation

• How to reduce risks in ART

10.35 Coffee break

11.00 Genetics in ART A. Capalbo (Italy) - D. Cimadomo (Italy)• Genetic screening in infertile populations • Pre-implantation genetic diagnosis for monogenic andchromosomal abnormalities

• Pre-implant genetic diagnosis for aneuploidy testing• Non invasive pre natal testing

12.30 Interactive discussion

13.00 Lunch

Clinical workup and laboratory technologies Session I

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14.00 Laboratory technologiesOverview of the modern IVF Lab: Lab technologies neededto maximize success L. Rienzi (Italy)• Embryo culture• Embryo assesment today• Oocyte and embryo vitrification: current state

15.00 Coffee break

15.30 Management of high responders and prevention of OHSSS. Colamariai (Italy)

16.30 End of the first day

IVF Lab Session II

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Friday, 23 September

Meeting point:

G.EN.E.R.A. Training CenterVia Giuseppe de Notaris, 1E - 00197 Rome, Italy

09.30 Management of poor responder / Natural cycle IVFA. Vaiarelli (Italy)

10.30 Coffee break

Parallel sessions - D. Cimadomo (Italy) - A. Vaiarelli (Italy)

13.00 Video session and clinical cases discussionD. Cimadomo (Italy) - A. Vaiarelli (Italy)

13.45 Concluding remarks

14.00 End of the course

Closing lunch

Clinical cases and clinic tourSession III

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Group A

IVF unit tour

Clinical cases presentations

Group B

Clinical cases presentations

IVF unit tour

11.00

12.00

IVF unit tourVisit to the GENERA Centre’s Operating Theatre and Embryo Lab.Visit to the unit will be planned according to the treatments in programmeduring those days. Participants will visit the following activities:• Oocyte retrieval• Oocytes insemination• Embryos and blastocyst evaluation• Blastocyts stage biopsy for PGD PGS• Embryo transfer procedure• Oocyte and embryo cryopreservation• Testicular sperm extraction

Clinical casesThere will be description and interactive discussion concerning real cases.Participants are also invited to send their own clinical cases in advance sothat they can be studied and discussed with the experts during the clinicalcases sessions.

General information

VenueThis live educational course takes place at the:

G.EN.E.R.A. Center for Reproductive Medicine, Valle Giulia ClinicVia Giuseppe de Notaris, 200197 Rome, Italy

and

G.EN.E.R.A. Training CenterVia Giuseppe de Notaris, 1E00197 Rome, Italy

LanguageThe official language of this course is English.

CME ProviderEXCEMED - Excellence in Medical Education

Senior Programme Manager: Chloé Xilinas T +39 06 420413 505 - F +39 06 420413 677chloe.xilinas@excemed.org

Medical Advisor: Alberto Vaiarellialberto.vaiarelli@gmail.com

For any logistic support please contact:

Meridiano Congress International Congress Manager: Andrea GruppusoT +39 06 88595 241 - F +39 06 88595 234 andrea.gruppuso@meridiano.it

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Disclosure of faculty relationships

EXCEMED adheres to guidelines of the European AccreditationCouncil for Continuing Medical Education (EACCME®) and all otherprofessional organisations, as applicable, which state thatprogrammes awarding continuing education credits must bebalanced, independent, objective, and scientifically rigorous.Investigative and other uses for pharmaceutical agents, medicaldevices, and other products (other than those uses indicated inapproved product labeling/package insert for the product) may bepresented in the programme (which may reflect clinical experience,the professional literature or other clinical sources known to thepresenter). We ask all presenters to provide participants withinformation about relationships with pharmaceutical or medicalequipment companies that may have relevance to their lectures. Thispolicy is not intended to exclude faculty who have relationships withsuch companies; it is only intended to inform participants of anypotential conflicts so that participants may form their ownjudgements, based on full disclosure of the facts. Further, all opinionsand recommendations presented during the programme and allprogramme-related materials neither imply an endorsement nor arecommendation on the part of EXCEMED. All presentationsrepresent solely the independent views of the presenters/authors.

The following faculty provided information regarding significantcommercial relationships and/or discussions of investigational ornon-EMEA/FDA approved (off-label) uses of drugs:

Antonio Capalbo Declared no potential conflict of interest.

Danilo Cimadomo Declared no potential conflict of interest.

Silvia Colamaria Declared no potential conflict of interest.

Laura Rienzi Declared no potential conflict of interest.

Filippo Maria Ubaldi Declared no potential conflict of interest.

Alberto Vaiarelli Declared no potential conflict of interest.

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Better outcomes for patients start here.With over 40 years in the field, EXCEMED has been delivering CME-accredited programmes longer than any other provider

in Europe, and now offers CME worldwide.

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absolute best in CME. With four decades of achievement behind us and access to the world’spremiere medical experts, better outcomes for patients start here. About EXCEMED.

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All EXCEMED programmes are organized solely to promote the exchangeand dissemination of scientific and medical information. No forms ofpromotional activities are permitted. There may be presentations discussinginvestigational uses of various products. These views are the responsibility ofthe named speakers, and do not represent an endorsement orrecommendation on the part of EXCEMED. This independent programme issupported by independent educational grants received from Merck KGaA,Darmstadt Germany, and MVZ Fertility Center Hamburg.

EXCEMED - Excellence in Medical EducationHeadquarters14, Rue du Rhône - 1204 Geneva, SwitzerlandRepresentative OfficeSalita di San Nicola da Tolentino 1/b - 00187 Rome, ItalyT +39 06 420413 1 - F +39 06 420413 677

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