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120×120

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specimen,

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Region of

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relaxation

respective

mean visc

were stati

Discussjoint funct

significan

support to

degenerat

cartilage a

needed to

ADC and

non-invas

Referen440-4. Li

Li X et al.

uation of visc

Takak

gical Science, To

Center, Anesaki,

chnology, Tsukub

ve: Apparent

correlate main

ge correlate wit

for the mecha

vestigate the co

by indentation

ds: ADC of

was measured

coefficient we

mples was acq

quence with th

mm, matrix 2

d 1500 s/mm2

, medial and la

were analyzed

f interest was d

s: Morphologic

correction wer

n time and visc

ely, p<0.01, Fig

cosity coefficie

stically signifi

sion and Cotion, where it a

nt correlation ob

o the notion tha

ive cartilage. F

and incorporati

confirm this. I

viscoelasticity

sive method of

nces: Mlynár

i LP et al. Med

. Osteoarthritis

coelasticity inko Aoki1, Atsuya

okyo Metropolita

Chiba, Japan, 3B

ba, Ibaraki, Japa

diffusion coef

nly with water c

th viscoelastici

anical strength

orrelation betw

n testing.

porcine knee

d by using a 3

re measured u

quired using a

he following pa

56×256, slice

(Total scan tim

ateral femoral c

d for both MR

drawn over the

cal sagittal ima

re shown in fig

osity coefficien

g. 2-3). The me

ent values show

cant (p<0.05).

onclusion: acts as a shock

bserved betwe

at ADC can be

Further studies

ing biochemica

In conclusion,

y was observed

assessing carti

rik V et al. J M

dical Engineeri

s and Cartilage

n early degena Watanabe2, Nao

an University, Ar

Biomedical Sens

an, 4Radiology, S

fficient (ADC)

content in carti

ity of cartilage

of cartilage. T

ween ADC and

(n =20, age

3-Tesla MRI .

sing an indent

a single shot

arameters: TR/

thickness 3.0

me 1 min 48 se

condyle as wel

R imaging an

whole area of

age and ADC m

gure 1. ADC w

nt (R2=0.7532

ean relaxation

ws on table 1. A

Cartilage play

k absorber durin

en ADC and vi

also useful for

including kne

al and histolog

a significant c

d, indicating tha

ilage viscoelas

Magn Reson Ima

ng & Physics 2

e 2007; 15(7): 7

nerative cartotaka Nitta3, Ak

rakawa-ku, Tokyo

sing and Imaging

Saitama Medical

of cartilage ha

ilage. As water

e, ADC can be

The aim of this

viscoelasticity

e 6 months)

. Relaxation t

ation device T

spin echo-ech

/TE 4000/47 m

mm, b values

ec). Four sites

ll as medial an

nd indentation

superficial lay

mapping with

was correlated w

and 0.6894,

time values an

All of these dif

ys a critical rol

ng joint loadin

iscoelasticity l

r the evaluation

es with degene

gical analysis a

orrelation betw

at ADC can ser

sticity.

aging 2003; 17

2008; 30: 182–

789-797

tilage using aira Furukawa1, a

o, Japan, 2Ortho

g, National Insti

l University Hosp

as been

r content

a useful

study

y

articular

time and

The ADC

o planar

ms, FOV

s 0, 700,

s in each

nd lateral

testing.

yer.

with

nd the

fferences

e in

ng. The

ends

n of

erative

re

ween

rve as a

7(4):

–189.

Figw

Fir

Fiv

apparent diffand Mamoru Niit

opedic Surgery, T

tute of Advanced

pital, Iruma-gun

g. 1 MR imagwith distortion

ig. 2 Correlatirelaxation tim

ig. 3 Correlativiscosity coef

fusion coeffictsu4

Teikyo University

d Industrial Scie

n, Saitama, Japa

ge and ADC mn correction

tion between Ame

tion between Afficient

cient

y Chiba

ence and

n

mapping

ADC and

ADC and

3299Proc. Intl. Soc. Mag. Reson. Med. 20 (2012)