nmiopth
TRANSCRIPT
Nuclear Medicine Week 2006
Nuclear Medicine In Opthalmology
Dr.V.SIVASUBRAMANIYAN
Dept.Of Nuclear Medicine
SRI SATHYA SAI INSTITUTE OF HIGHER MEDICAL SCIENCES,
Prashanthinilaym.
? NUCLEAR MEDICINE
INTERNAL ADMINISTRATION OF RADIO-ACTIVE ISOTOPES FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES IS TERMED AS NUCLEAR MEDICINE
DIAGNOSTIC APPLICATIONS
DACRYOSCINTIGRAPHY GALLIUM SCAN I-131 MIBG SCANS I-131 BZA SCANS RADIOIMMUNOSCINTIGRAPHY PET – CT EVALUATION
NUCLEAR THERAPY
Gamma emitters
Brachytherapy
Radio-immunotherapy
Yttrium Application in Pterygium
Yt.90 LIMBAL APPLICATION
Pterygium Treatment Protocol
Includes Post-surgical Limbal Yt-90 appication with applicator
Reduces the recurrence to < 5 %
Nasolacrimalduct Apparatus
LACRIMAL PASSAGE IMAGING
INVSIVE IMAGING CONTRAST
DACRYOCYSTOGRAPHY NON-INVASIVE IMAGING DACRYOSCINTIGRAPHY Helical C.T evaluation M. R dacryocystography
Contrast Dacryocystography
Advantage Good Anatomical Delineation Therapeutic Sometimes Disadvantages Radiation Burden Contrast Reactions Non- Physiological
DACRYOSCINTIGRAPHY
Scintigraphic evaluation of Nasolacrimal Duct evaluation
Radiopharmaceutical – Tc99m Pertech.
Dose 50 microcurie
METHODOLOGY
Route : TOPICAL APPLICATION Position: Supine or Sitting Site : Lower eyelid Instrumentation :
Micropipette,Gc Dynamic Acquisition Delayed Images
INDICATIONS
Advantage Dacryoscintigraphy
Absolutely Non-invasive
Dry Run instruction possible
No Contrast agents
No hazards of Allergic reactions
RADIATION DOSE TO LENS
NORMAL EYE 2.2x10(-5) Rad/micro curie
Obstructed EYE 4.0X10(-3)Rad/micro curie
J.ROBERTSON etal Radiology Vol 133,
747-750, 1979
Cost Benefit Analysis
No additional Financial burden Micro-curie dose only Helps in limiting the Wastage Machine time is scheduled in a
such a way other major studies are nor affected.
MR DACRYOCYSTOGRAPHY
Advantage Good Soft Tissue Delineation Funcitonal evaluation possible Disadvantage Costly Not affordable
Thank You