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ELISA KitsEnzyme-linked Immunosorbent Assays

Metabolic Syndrome BiomarkersObesity/Type 2 Diabetes MarkersInsulin Resistance MarkersCardiovascular Markers

Inflammatory Diseases BiomarkersRheumatoid ArthritisNeuroinflammation Markers

Cancer & Autoimmune Diseases Biomarkers

Cymax™ Cytokine ELISA Kits

Biomarkersadiponectin 2anGPtl3 2anGPtl6 2baff 2caspase-1 2dlk1 3GPX1 3GPX3 3il-1a 3il-33 3il-36b 4il-36g 4il-36ra 4il-37 4il-38 4irisin 4nampt/Visfatin 5Periostin 5Progranulin 5rbP4 5– 6relM-b 6resistin 6Sirtuin 1 6Vaspin 6Zinc-a-2-Glycoprotein 6cymax™ cytokine eliSa kits [interleukins, interferon, tnf-a, etc.] 7oxidative Stress Marker assays 8trace element assays 8

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2nd Edition

Nuovi ELISA Kit

Tel 0571 568147 - vb@vincibiochem.it

APRIL (human) ELISA Kit

AG-45B-0012-KI01 96 wells Assay Range: 7.8 to 500 pg/ml. Sensitivity: 7 pg/ml. Sample Type: Cell Culture Supernatant, Plasma, Serum. Colorimetric sandwich assay. APRIL is implicated in the regulation of tumor cell growth, is involved in monocyte/macrophage-mediated immunological processes and functions as an important survival factor for plasmablasts and bone marrow plasma cells. Manual

APRIL/BAFF (human) Tandem ELISA Kit

AG-45B-4501-KI02 2 x 96 wells Assay Range: 7.8 to 500 pg/ml for APRIL (human) ELISA Kit; 15.6 – 500 pg/ml for BAFF (human) ELISA Kit. Sensitivity: 7 pg/ml for APRIL (human) ELISA Kit; 8 pg /ml for BAFF (human) ELISA Kit. Sample Type: Cell Culture Supernatant, Plasma, Serum. Assay Type: Sandwich.The new Tandem format includes 1 x BAFF (human) ELISA kit (AG-45B-0001) and 1 x APRIL (human) ELISA (AG-45B-0012) kit that can be used to measure both BAFF (human) and APRIL (human) in biological fluids. Manual

Asprosin (human) Matched Pair Detection Set

AG-46B-0011-KI01 1 Set Assay Range: 0.156 to 10 ng/ml. Sensitivity: 150 pg/ml. Sample Type: Cell Culture Supernatant. Detection Type: Colorimetric. Assay Type: Sandwich. Asprosin function could serve as a potentially unique therapeutic target against obesity, diabetes or metabolic diseases. Manual

CD40L (human) ELISA Kit

AG-45B-0018-KI01 96 wells Assay Range: 0.03125 to 2 ng/ml. Sensitivity: 20 pg/ml. Sample type: Cell Culture Supernatant, Plasma, Serum. Colorimetric sandwich assay. CD40-CD40L interactions are crucially involved in development of autoimmune disease and have also impact on growth regulation of certain carcinomas. Manual

Erythroferrone (human) ELISA Kit

AG-45B-0014-KI01 96 wells Assay Range: 0.3125 to 20 ng/ml. Sensitivity: 270 pg/ml. Sample type: Cell Culture Supernatant, Plasma, Serum. Colorimetric sandwich assay. Erythroferrone is a biomarker for different types of anemia, for cardiology and potentially also for metabolic diseases. Manual

FGL1 (human) ELISA Kit

AG-45B-0022-KI01 96 wells Assay Range: 7.8 to 500pg/ml. Sensitivity: 1.8pg/ml. Sample Type: Cell Culture Supernatant, Plasma, Serum. Colorimetric sandwich assay. Fibrinogen-like protein 1 was initially identified as an overexpressed transcript in hepatocyte carcinoma and as a transcript enriched in regenerating liver. FGL1 is expressed at lower levels in brown and white adipose in the setting of liver injury. Recently, FGL1 has also been shown to be upregulated in human cancers and FGL1 is a major functional ligand of LAG-3. Manual

Gasdermin D (mouse) ELISA Kit

AG-45B-0011-KI01 96 wells Assay Range: 15.6 to 1000 pg/ml. Sensitivity: 14pg/ml Sample Type: Cell Culture Supernatant, Cell Lysate. Colorimetric sandwich assay. Detects full-length and cleaved mouse Gasdermin D (C-terminus). The cleavage of the intracellular gasdermin D by caspases leads to a particular form of inflammatory cell death called pyroptosis. Manual

ICOSL (B7-H2/CD275) (human) ELISA Kit

AG-45B-0017-KI01 96 wells Assay Range: 0.0625 to 4 ng/ml. Sensitivity: 55 pg/ml. Sample type: Cell Culture Supernatant, Plasma, Serum. Colorimetric sandwich assay. ICOSL sheds from the cell membrane and the soluble form of ICOSL (sICOSL), found in plasma and sera, can be a potential biomarker for autoimmune diseases and some cancers. Manual

IL-36alpha (human) ELISA Kit

AG-45B-0013-KI01 96 wells Assay Range: 7.8 to 500pg/ml. Sensitivity: 4 pg/ml. Sample type: Cell Culture Supernatant, Plasma, Serum. Colorimetric sandwich assay. Detects natural and recombinant human IL-36alpha (IL-1F6). IL-36 family members may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination. Manual

IL-36alpha/IL-36gamma (human) Tandem ELISA

AG-45B-4502-KI02 2 x 96 wells Assay Range: 7.8 to 500 pg/ml for IL-36α (human) ELISA Kit; 3.9 – 250 pg/ml for IL-36γ (human) ELISA Kit. Sensitivity: 4 pg/ml for IL-36α (human) ELISA Kit; 3 pg /ml for IL-36γ (human) ELISA Kit. Sample type: Cell Culture Supernatant, Serum. Colorimetric sandwich assay. The new Tandem format includes 1 x IL-36alpha (human) ELISA kit (AG-45B-0013) and 1 x IL-36gamma ELISA kit (AG-45B-0008) that can be used to measure both IL-36alpha (human) and IL-36gamma (human) in biological fluids. Manual

PD-1 (human) ELISA Kit

AG-45B-0015-KI01 96 wells Assay Range: 3.125 to 200 pg/ml. Sensitivity: 1.6 pg/ml. Sample Type: Cell Culture Supernatant, Plasma, Serum. Assay Type: Sandwich. Soluble checkpoints, such as sPD-1 or sPD-L1, are involved in positive or negative immune regulation and changes in their serum/plasma levels affect the development, prognosis and treatment of cancer. Manual

PD-L1 (human) ELISA Kit

AG-45B-0016-KI01 96 wells Assay Range: 2.34 to 150pg/ml. Sensitivity: 0.8pg/ml. Sample Type: Cell Culture Supernatant, Plasma, Serum. Assay Type: Sandwich. Manual

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2Metabolic SyndroMe bioMarkerS inflaMMatory diSeaSeS bioMarkerS cancer & autoiMMune diSeaSeS bioMarkerS

GloSSary: CVD: Cardiovascular Disease; NAFLD: Non-Alcoholic Fatty Liver Disease; SLE: Systemic Lupus Erythematosus; RA: Rheumatoid Arthritis

Adiponectin Metabolic Syndrome, Obesity, Insulin Resistance, Type 2 Diabetes (T2D), CVD, NAFLD, Obesity-related Inflammation, Various Cancers

adiponectin (human) eliSa kit the Standard AG-45A-0001Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.5 to 32 ng/mlSensitivity: 100 pg/ml Sample type: Serum, Plasma, Urine, Cell Culture Supernatant

adiponectin (mouse) eliSa kit AG-45A-0004Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Mouse Range: 0.125 to 8 ng/mlSensitivity: 50 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

adiponectin (rat) eliSa kit AG-45A-0005Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Rat Range: 0.375 to 24 ng/mlSensitivity: 50 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

ANGPTL3Metabolic Syndrome, CVD, NAFLD, Insulin Resistance, Rheumatoid Arthritis, Atherosclerosis

anGPtl3 (human) eliSa kit AG-45A-0014Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.156 to 10 ng/mlSensitivity: 75 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

anGPtl3 (mouse/rat) dual eliSa kit AG-45A-0015Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Mouse / Rat Range: 0.016 to 1 ng/mlSensitivity: 15 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

ANGPTL6 Metabolic Syndrome, Type 2 Diabetes (T2D), Obesity, Insulin Resistance, Preeclampsia

anGPtl6 (human) eliSa kit AG-45A-0016Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 1.56 to 100 ng/mlSensitivity: 1.2 ng/ml Sample type: Serum, Plasma, Cell Culture Supernatant

BAFF Autoimmune Diseases (Sjögren’s Syndrome, SLE, Pancreatitis & Hepatitis), Lymphomas, Inflammatory Diseases (Polymyositis, RA, Sarcoidosis)

baff, Soluble (human) eliSa kit (hypersensitive) AG-45B-0001 Available Size: 96 wells

Species reactivity: Human Range: 15.6 to 500 pg/mlSensitivity: 8 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

baff, Soluble (human) Matched Pair Detection Set AG-46B-0001 Reagents to perform 5 x 96 wells

Species reactivity: Human Range: 16 to 1000 pg/ml Sensitivity: 16 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

High Quality ELISA Kits Developed & Manufactured by

• Extensively validated • High Specificity, Sensitivity & Accuracy • Reproducible Results with low Inter- and Intra-Assay Variation• Many Citations in Peer-reviewed Key Literature References

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For updated prices and additional information visit www.adipogen.com or contact your local distributor.

3Metabolic SyndroMe bioMarkerS inflaMMatory diSeaSeS bioMarkerS cancer & autoiMMune diSeaSeS bioMarkerS

Caspase-1 Assay for measuring Inflammasome Activation

caspase-1 (mouse) eliSa kit AG-45B-0002 Available Size: 96 wells

Species reactivity: Mouse Range: 0.15 to 10 ng/mlSensitivity: 33 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

caspase-1 (mouse) Matched Pair Detection Set AG-46B-0003 Reagents to perform 5 x 96 wells

Species reactivity: Mouse Range: 0.15 to 10 ng/ml Sensitivity: 50 pg/ml Sample type: Cell Culture Supernatant

DLK1Metabolic Syndrome, Various Cancers, Preeclampsia, Steatosis

dlk1, Soluble (human) eliSa kit AG-45A-0032Y Available Size: 96 wells

Species reactivity: Human Range: 0.47 to 30 ng/ml Sensitivity: 336 pg/ml Sample type: Serum, Cell Culture Supernatant

GPX1 Various Cancers, Insulin Resistance, Obesity, Type 2 Diabetes (T2D)

GPX1 (human) eliSa kit AG-45A-0037Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.0625 to 4 ng/ml Sensitivity: 45 pg/ml Sample type: Plasma

GPX3 Hypertension, Type 2 Diabetes (T2D), CVD, Atherosclerosis, Amyotrophic Lateral Sclerosis (ALS)

GPX3 (human) eliSa kit AG-45A-0020Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.5 to 32 ng/ml Sensitivity: 100 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

IL-1a Assay for measuring Inflammasome Activation and corresponding Inflammatory Diseases

il-1a (mouse) eliSa kit AG-45B-0003 Available Size: 96 wells

Species reactivity: Mouse Range: 15.6 pg/ml to 1 ng/mlSensitivity: 9 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

il-1a (mouse) Matched Pair Detection Set AG-46B-0004 Reagents to perform 5 x 96 wells

Species reactivity: Mouse Range: 15.6 to 2000 pg/ml Sensitivity: 10 pg/ml Sample type: Cell Culture Supernatant

IL-33 Rheumatoid Arthritis, Autoimmune Diseases, Inflammatory Diseases, Various Cancers, Obesity, Diabetic Nephropathy, Atherosclerosis

il-33 (human) eliSa kit the Standard AG-45A-0033Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.016 to 1 ng/ml Sensitivity: 5 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

4Metabolic SyndroMe bioMarkerS inflaMMatory diSeaSeS bioMarkerS cancer & autoiMMune diSeaSeS bioMarkerS

GloSSary: COPD: Chronic Obstructive Pulmonary Disease; IBD: Inflammatory Bowel Disease, PCOS: Polycystic Ovary Syndrome

IL-36b Skin Inflammation

il-36b (human) Matched Pair Detection Set AG-46B-0009 Reagents to perform 5 x 96 wells

Species reactivity: Human Range: 15.6 to 1000 pg/mlSensitivity: 10 pg/ml Sample type: Cell Culture Supernatant

IL-36g Skin Inflammation, Psoriasis, Lung & Bowel Inflammation

il-36g (human) eliSa kit AG-45B-0008 Available Size: 96 wells

Species reactivity: Human Range: 3.9 to 250 pg/ml Sensitivity: 3 pg/ml Sample type: Serum, Cell Culture Supernatant

il-36g (human) Matched Pair Detection Set AG-46B-0010 Reagents to perform 5 x 96 wells

Species reactivity: Human Range: 3.9 to 250 pg/ml Sensitivity: 1 pg/ml Sample type: Cell Culture Supernatant

IL-36Ra Skin Inflammation

il-36ra (human) Matched Pair Detection Set AG-46B-0006 Reagents to perform 5 x 96 wells

Species reactivity: Human Range: 0.78 to 50 ng/mlSensitivity: 0.5 ng/ml Sample type: Cell Culture Supernatant

IL-37 Inflammatory Diseases, Autoimmune Diseases (SLE), Various Cancers, Asthma, Atherosclerosis

il-37 (human) eliSa kit AG-45A-0041Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.016 to 1 ng/ml Sensitivity: 10 pg/ml Sample type: Serum, Plasma

IL-38 Allergic Inflammation, Asthma, Autoimmune Diseases (SLE)

il-38 (human) Matched Pair Detection Set AG-46B-0007 Reagents to perform 5 x 96 wells

Species reactivity: Human Range: 0.031 to 2 ng/mlSensitivity: 20 pg/ml Sample type: Serum, Cell Culture Supernatant

Irisin Energy Metabolism, Obesity, Type 2 Diabetes (T2D), Insulin Resistance, COPD

irisin competitive eliSa kit AG-45A-0046Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human / Monkey / Mouse / Rat Range: 0.001 to 5 µg/mlSensitivity: 1 ng/ml Sample type: Serum, Plasma, Cell Culture Supernatant

LIT: Irisin, a novel myokine is an independent predictor for sarcopenia and carotid atherosclerosis in dialysis patients: M.J. Lee, et al.; Atheroscler. 242, 476 (2015) • Irisin levels in the progression of diabetes in sedentary women: I.D. Duran, et al.; Clin. Biochem. 48, 1268 (2015) • Chronic CNS oxytocin signaling preferentially induces fat loss in high-fat diet-fed rats by enhancing satiety responses and increasing lipid utilization: J.E. Blevins, et al.; Am. J. Physiol. 310, R640 (2016) • Eicosapentaenoic acid regulates brown adipose tissue metabolism in high-fat-fed mice and in clonal brown adipocytes: M. Pahlavanni, et al.; J. Nutr. Bioche. 39, 101 (2017)

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5Metabolic SyndroMe bioMarkerS inflaMMatory diSeaSeS bioMarkerS cancer & autoiMMune diSeaSeS bioMarkerS

Nampt / Visfatin Diabetes, Obesity, Sepsis, IBD, Crohn’s Disease, Rheumatoid Arthritis, Preeclampsia, Various Cancers

nampt [Visfatin/Pbef] (human) eliSa kit the Standard AG-45A-0006Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.125 to 8 ng/mlSensitivity: 30 pg/ml Sample type: Serum

nampt [Visfatin/Pbef] (human) (intracellular) eliSa kit AG-45A-0008Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.25 to 16 ng/ml Sensitivity: 30 pg/ml Sample type: Cell Lysate

nampt [Visfatin/Pbef] (mouse/rat) dual eliSa kit AG-45A-0007Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Mouse / Rat Range: 0.5 to 32 ng/mlSensitivity: 50 pg/ml Sample type: Serum

Periostin Asthma, Allergic Inflammation, Various Cancers, Metastasis in Epithelial Tumors, Renal Injury, Osteoarthritis

Periostin (human) eliSa kit AG-45B-0004 Available Size: 96 wells

Species reactivity: Human Range: 78 to 5000 pg/mlSensitivity: 15 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

Periostin (mouse) eliSa kit AG-45B-0005 Available Size: 96 wells

Species reactivity: Mouse Range: 31 to 2000 pg/mlSensitivity: 10pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

Periostin (human) Matched Pair Detection Set AG-46B-0005 Reagents to perform 5 x 96 wells

Species reactivity: Human Range: 80 to 5000 pg/ml Sensitivity: 30 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

Periostin (mouse) Matched Pair Detection Set AG-46B-0002 Reagents to perform 5 x 96 wells

Species reactivity: Mouse Range: 31 to 2000 pg/ml Sensitivity: 20 pg/ml Sample type: Serum, Cell Culture Supernatant

Progranulin FTLD, Rheumatoid Arthritis, Various Cancers, Type 2 Diabetes (T2D), Bipolar Disorder

Progranulin (human) eliSa kit the Standard AG-45A-0018Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.063 to 4 ng/ml Sensitivity: 32 pg/ml Sample type: Serum, Plasma, Urine, Cell Culture Supernatant, CSF

Progranulin (mouse) eliSa kit AG-45A-0019Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Mouse Range: 0.125 to 8 ng/ml Sensitivity: 60 pg/ml Sample type: Serum, Cell Culture Supernatant

Progranulin (rat) eliSa kit AG-45A-0043Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Rat Range: 0.063 to 4 ng/mlSensitivity: 40 pg/ml Sample type: Serum, Cell Culture Supernatant

RBP4 Insulin Resistance, Microalbuminuria, Type 2 Diabetes (T2D), CVD, Obesity, NAFLD, PCOS, Ovarian Cancer

rbP4 (human) eliSa kit (Quantitative) the Standard AG-45A-0035Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.39 to 25 ng/ml Sensitivity: 380 pg/ml Sample type: Serum, Plasma, Urine, Cell Culture Supernatant

6Metabolic SyndroMe bioMarkerS inflaMMatory diSeaSeS bioMarkerS cancer & autoiMMune diSeaSeS bioMarkerS

rbP4 (human) competitive eliSa kit AG-45A-0010Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.001 to 5 μg/ml Sensitivity: 1 ng/ml Sample type: Serum, Plasma, Urine, Cell Culture Supernatant

rbP4 (mouse/rat) dual eliSa kit AG-45A-0012Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Mouse / Rat Range: 0.188 to 12 ng/ml Sensitivity: 60 pg/ml Sample type: Serum, Urine, Cell Culture Supernatant

RELM-b Potential Gut-Inflammation, Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis

relM-b (human) Matched Pair Detection Set AG-46A-0001 Reagents to perform 5 x 96 wells

Species reactivity: Human Range: 0.016 to 1 ng/ml Sensitivity: 10 pg/ml Sample type: Human Feces

ResistinInsulin Resistance, Type 2 Diabetes (T2D), Obesity, NAFLD, Various Inflammatory Diseases

resistin (human) eliSa kit AG-45A-0023Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.125 to 8 ng/ml Sensitivity: 100 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

Sirtuin 1 Metabolic Syndrome, Type 2 Diabetes , Alzheimer’s Disease, Various Cancers, Inflammatory Diseases

Sirtuin 1 (human) (intracellular) eliSa kit AG-45A-0029Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.032 to 2 ng/mlSensitivity: 30 pg/ml Sample type: Cell Lysate

Vaspin Type 2 Diabetes (T2D), Obesity, Insulin Resistance, CVD, NAFLD, Inflammatory Diseases

Vaspin (human) eliSa kit the Standard AG-45A-0017Y Available Sizes: 96 wells / Twin Plex

Species reactivity: Human Range: 0.016 to 1 ng/mlSensitivity: 12 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

Visfatin see Nampt on Page 5

Zinc-a-2-glycoprotein (ZAG) Obesity, Various Cancers, Diabetic Nephropathy, Preeclampsia

ZaG (human) turboeliSa kit AG-48B-1000 Available Size: 96 wells

Species reactivity: Human Range: 0.9375 to 60 ng/mlSensitivity: 0.23 ng/ml Sample type: Serum, Plasma, Cell Culture Supernatant

ZaG (human) Matched Pair Detection Set AG-46B-0008 Reagents to perform 5 x 96 wells

Species reactivity: Human Range: 0.0156 to 1 ng/mlSensitivity: 100 pg/ml Sample type: Serum, Plasma, Cell Culture Supernatant

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Autoimmune Disease Biomarkers APRIL & BAFF

NEW APRIL (human) ELISA Kit The BEST on the Market !

BAFF, Soluble (human) ELISA Kit (hypersensitive) The RELIABLE Assay

APRIL (human) ELISA KitAG-45B-0012 96 wells

BAFF, Soluble (human) ELISA Kit (hypersensitive)AG-45B-0001 96 wells

NEW

The B cell-stimulating molecules, BAFF (B cell activating factor also known as BLyS; TALL-1; CD257 or TNFSF13B) and APRIL (a prolif-eration-inducing ligand, also known as CD256 or TNFSF13), are critical factors in the maintenance of the B cell pool and humoral im-munity. They are implicated in several human autoimmune diseases with autoreactive B cell involvement, including systemic lupus erythematosus (SLE), Sjogren’s syndrome (SS), IgA nephropathy (IgAN) and rheumatoid arthritis (RA). APRIL might also function in enhancing proliferation of some tumor cells, especially B cell malignancies and BAFF levels are increased in some lymphoid cancers.

The APRIL (human) ELISA Kit (Prod. No. AG-45B-0012) is a sandwich ELISA for specific quantitative determination of human APRIL in serum, plasma and cell culture supernatants. This ELISA Kit shows both high specificity and high sensitivity, which is a clear advantage compared to other APRIL (human) ELISA Kits from key competitors.

The BAFF, Soluble (human) ELISA Kit (Prod. No. AG-45B-0001) is a sandwich ELISA for specific quantitative determination of human BAFF in serum, plasma and cell culture supernatants. This ELISA Kit does not cross-react with mouse BAFF and has been chosen by sev-eral CROs for its high specificity and high sensitivity.

UNIQUE

Specificity: Serum from a healthy patient is left untreated or treated with 1 µg/ml of the APRIL receptor, TACI (human):Fc (human) (Prod. No. AG-40B-0079). APRIL levels were measured using the APRIL (human) ELISA Kit (Prod. No. AG-45B-0012).

Specificity: Serum from a healthy patient or patient with multiple sclerosis is left untreated or treated with 0.5 μg/ml of a BAFF receptor, TACI (human):Fc (human) (AG-40B-0079). BAFF levels are measured using the BAFF, Soluble (human) ELISA Kit (hypersensitive) (AG-45B-0001).

Best-In-Class APRIL & BAFF ELISA Kits

Sensitivity: 7 pg/ml Range: 7.8 to 500 pg/ml Sample: Cell Culture Supernatant, Plasma, Serum

Sensitivity: 8 pg/ml Range: 15.6 to 500 pg/ml Sample: Cell Culture Supernatant, Plasma, Serum

ng/m

l APR

IL in

ser

um

Serum + TACI-Fc Serum

1,401,201,000,800,600,400,200,00 0

10

20

30

40

50

BAFF

[ng/

ml]

TACI (h):Fc 500ng/ml- + - +

healthy Multiple myeloma

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This ELISA Kit is for Research Use Only (RUO).

Erythroferrone (human) ELISA Kit The only Specific & Sensitive Assay on the Market!

Erythroferrone (also called Myonectin, CTRP15, Fam132B or ERFE) is a hormone produced by erythroblasts in the

bone marrow in response to erythropoietin controlling iron storage release or is a myokine abundantly expressed in

skeletal muscle tissue, upregulated by voluntary exercise. Erythroferrone/Myonectin is a potential clinical biomarker

for assessing erythropoiesis in patients with blood disorders, to study iron homeostasis for cardiovascular/heart

protection, and potentially for metabolic disorders.

NEW Erythroferrone (human) ELISA Kit

AG-45B-0014 96 wells

Sensitivity: 270 pg/ml

Range: 0.3125 to 20 ng/ml

Sample: Cell Culture Supernatant, Plasma, Serum

This Erythroferrone (human) ELISA Kit is a Sandwich assay

based on two antibodies and is to be used for the in vitro

quantitative determination of human Erythroferrone in

cell culture supernatants, serum and plasma. Levels of

Erythroferrone measured by this ELISA kit in serum and

plasma correspond to mouse protein levels (~ 500 ng/ml).

J U S T RELEASED

FEATURES OF THIS ASSAY

4 High Specificity

4 High Sensitivity

4 High Reproducibility

4 Tested & Validated on many Samples

4 Swiss Quality Guarantee

MANUFACTURED IN SWITZERLANDMANUFACTURED IN SWITZERLANDMANUFACTURED IN SWITZERLAND

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Gasdermin D Signaling & Inflammasome Research

Gasdermin D (mouse) ELISA Kit

Gasdermin D (mouse) ELISA KitAG-45B-0011 96 wells

Detects full-length and cleaved C-terminal mouse Gasdermin D in cell culture superna-tants and cell extracts. Does not cross-react with human Gasdermin D.

NEW

Pyroptosis is an inflammatory programmed cell death that is initiated in response to pathogen- or host-derived perturbations of the cytosol. In human and mice pyroptosis is induced by inflammatory caspases, such as caspase-1 and -11 that are activated by inflammasomes. Gasdermin D (GSDMD) is a central mediator of pyroptotic cell death. It contains a functional N-terminal domain and an inhibitory C-terminal domain. Upon caspase-1/11 cleavage of the linker located between the two domains of Gasdermin D, the cleaved N-terminal fragment of Gasdermin D oligomerizes and forms pores on the host cell membrane, leading to cell death called pyroptosis.

AdipoGen Life Sciences is the leading manufacturer and supplier of inflammasome signaling research reagents. The validated high quality inflammasome research tools are used and published daily by the experts in the inflammasome research field.

The Gasdermin D (mouse) ELISA Kit (Prod. No. AG-45B-0011) is a sandwich ELISA for quantitative determination of mouse Gasder-min D in cell culture supernatants and in cell extracts. This ELISA is specific for the measurement of natural and recombinant mouse Gasdermin D (full-length and C-terminus cleaved fragment). It does not detect human Gasdermin D.

UNIQUE

FIGURE 1 FIGURE 2Specificity:

Gasdermin D is tested from supernatants of Bone Marrow-Derived Macrophages cells (BMDMs)transfected with LPS from different knockout mice strains (see Figure 1). Only the supernatants from WT and NLRP3-/- strains contain the protein Gasdermin D. Gasdermin D is also tested from cell extracts (lysed with a Triton X-100 buffer) of Bone Marrow-Derived Macrophages cells from WT and Gasdermin D knockout mice strains (see Figure 2).

A New Tool to Measure Pyroptosis:

Sensitivity: 14 pg/ml

Range: 15.6 to 1000 pg/ml

Sample: Cell Culture Supernatant, Cell Lysate

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7Metabolic SyndroMe bioMarkerS inflaMMatory diSeaSeS bioMarkerS cancer & autoiMMune diSeaSeS bioMarkerS

• high Specificity, Sensitivity & accuracy• reproducible results with low inter- and intra-assay Variation• Very competitive Prices• developed by the leading antibody & Protein Manufacturer

CYTOKINE ELISA Kits

PRODUCT NAME PID DETECTION RANGE SENSITIVITY SIZE

cymax™ eGf (human) eliSa kit YIF-LF-EK0296 3.9 – 250 pg/ml 0.055 pg/ml 1 x 96 wellscymax™ G-cSf (human) eliSa kit YIF-LF-EK0294 31.2 – 2000 pg/ml 2.790 pg/ml 1 x 96 wellscymax™ GM-cSf (mouse) eliSa kit YIF-LF-EK0283 3.9 – 250 pg/ml 1.53 pg/ml 1 x 96 wellscymax™ ifn-g (human) eliSa kit YIF-LF-EK0288 15.6 – 1000 pg/ml 15.262 pg/ml 1 x 96 wellscymax™ ifn-g (mouse) eliSa kit YIF-LF-EK0289 3.9 – 250 pg/ml 0.831 pg/ml 1 x 96 wellscymax™ il-1a (human) eliSa kit YIF-LF-EK0290 3.9 – 250 pg/ml 0.521 pg/ml 1 x 96 wellscymax™ il-1a (mouse) eliSa kit YIF-LF-EK0282 1.56 – 100 pg/ml 0.356 pg/ml 1 x 96 wellscymax™ il-1b (human) eliSa kit YIF-LF-EK0276 3.9 – 250 pg/ml 1.90 pg/ml 1 x 96 wellscymax™ il-1b (mouse) eliSa kit YIF-LF-EK0284 12.5 – 800 pg/ml 20 pg/ml 1 x 96 wellscymax™ il-2 (human) eliSa kit YIF-LF-EK0257 6.25 – 400 pg/ml 1.0052 pg/ml 1 x 96 wellscymax™ il-2 (mouse) eliSa kit YIF-LF-EK0279 3.9 – 250 pg/ml 0.207 pg/ml 1 x 96 wellscymax™ il-3 (human) eliSa kit YIF-LF-EK0272 31.25 – 2000 pg/ml 15.45 pg/ml 1 x 96 wellscymax™ il-3 (mouse) eliSa kit YIF-LF-EK0267 6.25 – 400 pg/ml 1.214 pg/ml 1 x 96 wellscymax™ il-4 (human) eliSa kit YIF-LF-EK0258 1.56 – 100 pg/ml 0.3757 pg/ml 1 x 96 wellscymax™ il-4 (mouse) eliSa kit YIF-LF-EK0268 7.8 – 500 pg/ml 0.707 pg/ml 1 x 96 wellscymax™ il-4 (rat) eliSa kit YIF-LF-EK0273 7.8 – 500 pg/ml 1.155 pg/ml 1 x 96 wellscymax™ il-5 (human) eliSa kit YIF-LF-EK0259 3.9 – 250 pg/ml 1.062 pg/ml 1 x 96 wellscymax™ il-5 (mouse) eliSa kit YIF-LF-EK0269 15.6 – 1000 pg/ml 2.556 pg/ml 1 x 96 wellscymax™ il-6 (human) eliSa kit YIF-LF-EK0260 4.68 – 300 pg/ml 1.160 pg/ml 1 x 96 wellscymax™ il-6 (mouse) eliSa kit YIF-LF-EK0270 7.8 – 500 pg/ml 1.138 pg/ml 1 x 96 wellscymax™ il-6 (rat) eliSa kit YIF-LF-EK0224 62.5 – 4000 pg/ml 26.643 pg/ml 1 x 96 wellscymax™ il-8 (human) eliSa kit YIF-LF-EK0262 0.78 – 50 pg/ml 0.278 pg/ml 1 x 96 wellscymax™ il-9 (human) eliSa kit YIF-LF-EK0281 1.56 – 100 pg/ml 0.252 pg/ml 1 x 96 wellscymax™ il-10 (human) eliSa kit YIF-LF-EK0263 7.8 – 500 pg/ml 0.820 pg/ml 1 x 96 wellscymax™ il-10 (mouse) eliSa kit YIF-LF-EK0298 31.25 – 2000 pg/ml 15.747 pg/ml 1 x 96 wellscymax™ il-12 (p70) (human) eliSa kit YIF-LF-EK0264 7.8 – 500 pg/ml 4.79 pg/ml 1 x 96 wellscymax™ il-12 (p70) (mouse) eliSa kit YIF-LF-EK0271 7.8 – 500 pg/ml 4.16 pg/ml 1 x 96 wellscymax™ il-12/il-23 p40 (mouse) eliSa kit YIF-LF-EK0297 15.6 – 1000 pg/ml 2.898 pg/ml 1 x 96 wellscymax™ il-13 (mouse) eliSa kit YIF-LF-EK0299 7.8 – 500 pg/ml 7.153 pg/ml 1 x 96 wellscymax™ il-15 (human) eliSa kit YIF-LF-EK0308 7.8 – 500 pg/ml 0.305 pg/ml 1 x 96 wellscymax™ il-17 (human) eliSa kit YIF-LF-EK0295 31.25 – 2000 pg/ml 2.134 pg/ml 1 x 96 wellscymax™ il-17 (mouse) eliSa kit YIF-LF-EK0303 10.9 – 700 pg/ml 3.573 pg/ml 1 x 96 wellscymax™ lt-a [tnf-b] (human) eliSa kit YIF-LF-EK0307 31.25 – 2000 pg/ml 7.762 pg/ml 1 x 96 wellscymax™ McP-1 (rat) eliSa kit YIF-LF-EK0305 15.6 – 1000 pg/ml 8.221 pg/ml 1 x 96 wellscymax™ tnf-a (human) eliSa kit YIF-LF-EK0193 15.6 – 1000 pg/ml 1.47 pg/ml 1 x 96 wellscymax™ tnf-a (mouse) eliSa kit YIF-LF-EK0275 7.8 – 500 pg/ml 2.535 pg/ml 1 x 96 wellscymax™ tnf-a (rat) eliSa kit YIF-LF-EK0280 12.5 – 800 pg/ml 3.159 pg/ml 1 x 96 wellscymax™ trail (human) eliSa kit YIF-LF-EK0266 23.4 – 1500 pg/ml 0.065 pg/ml 1 x 96 wells

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Unique High Quality ImmunoAssays

PRODUCT NAME PID DETECTION RANGE SAMPLES TYPES SIZE

dityrosine [dt] eliSa kit JAI-KDT-010E 0.05 – 12 µmol/L UR 1x 96 wells

8-ohdG check eliSa kit JAI-KOG-200SE 0.5 – 200 ng/mL UR 1x 96 wells

8-ohdG check eliSa kit (high Sensitivity) JAI-KOG-HS10E 0.125 – 10 ng/mL PL, SE, UR 1x 96 wells

hexanoyl-lys [hel] eliSa kit JAI-KHL-700E 2 – 700 nmol/L SE, UR 1x 96 wells

total antioxidant capacity (Pao) test kit JAI-KPA-050 21.9 – 4378 µmol/L (cupric ion reducing power)

PL, SE 1x 96 wells

PRODUCT NAME PID DETECTION RANGE SAMPLES TYPES SIZE

iron assay kit (ferrozine Method) JAI-CFE-005 5 – 1000 µg/dL CL, PL, SA, SE, TS, UR 100 tests

iron assay kit (nitroso-PSaP Method) JAI-CFE-010 10 – 1000 µg/dL CL, PL, SA, SE, TS, UR 100 tests

uibc assay kit (bathophenanthroline Method) JAI-CBC-800 10 – 800 µg/dL PL, SE 100 tests

copper assay kit (3,5-dibr-PaeSa Method) JAI-CCU-400 3 – 400 µg/dL CL, PL, SA, SE, TS, UR 100 tests

Zinc assay kit (5-br-PaPS Method) JAI-CZN-001 4 – 1000 µg/dL CL, PL, SA, SE, TS, UR 100 tests

calcium assay kit (chlorophosphonazo-iii Method) JAI-CCA-020 0.2 – 20 mg/dL CL, PL, SA, SE, TS, UR 200 tests

calcium assay kit (o-cresolphthalein Method) JAI-CCA-030 0.2 – 30 mg/dL CL, PL, SA, SE, TS, UR 200 tests

Magnesium assay kit (Xylidyl blue-i Method) JAI-CMG-035 0.2 – 3.5 mg/dL CL, PL, SA, SE, TS, UR 100 tests

Oxidative Stress Marker Assays

Trace Element Colorimetric Assays

Specific Marker for Psoriasis New Anti-Inflammatory Cytokine

Sample types: CL=Cell Lysate; PL=Plasma; SA=Saliva; SE=Serum; TS=Tissue Supernatant; UR=Urine

U N I Q U E IL-36g & IL-37 ELISA Kits

il-36g (human) eliSa kitAG-45B-0008 96 wells

IL-36g is a specific marker for Psoriasis. This assay is highly specific for human IL-36g. Does not cross-react with human IL-36a and IL-36b.

Sensitivity: 3 pg/ml | range: 3.9 to 250 pg/ml Sample: Serum, Cell Culture Supernatant

il-37 (human) eliSa kitAG-45A-0041Y 96 wells | TwinPlex

IL-37 is a new anti-inflammatory cytokine. This assay detects natural and recombinant monomeric and dimeric human IL-37.

Sensitivity: 10 pg/ml | range:  16 to 1000 pg/ml Sample: Serum, Plasma

LIT: Homodimerization attenuates the anti-inflammatory activity of interleukin-37: A.M. Ellisdon, et al.; Sci. Immunol. 2, eaaj1548 (2017)

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EUROPE/REST OF WORLDAdipogen InternationalTEL +41-61-926-60-40FAX +41-61-926-60-49info@adipogen.com

NORTH & SOUTH AMERICAAdipogen Corp.TEL +1-858-457-8383FAX +1-858-457-8484info-us@adipogen.com

For local distributors please visit our website.

In Italy: Vinci-Biochem SrlContatto diretto: tel. 0571 568 147vb@vincibiochem.itwww.vincibiochem.it

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