Siemens Healthcare Diagnostics, a global leader in clinical diagnostics, provides healthcare professionals in hospital, reference, and physician office laboratories and point-of-care settings with the vital information required to accurately diagnose, treat, and monitor patients. Our innovative portfolio of performance-driven solutions and personalized customer care combine to streamline workflow, enhance operational efficiency, and support improved patient outcomes.

MicroScan is a trademark of Siemens Healthcare Diagnostics Inc.

Not available for sale in the U.S.

Product availability may vary from country to country and is subject to varying regulatory requirements. Please contact your local representative for availability.

Order No. A91DX-MM-131347-GC1-4A00 11-2013 | All rights reserved © 2013 Siemens Healthcare Diagnostics Inc.

Global Siemens Headquarters Siemens AG Wittelsbacherplatz 2 80333 Muenchen Germany

Global Siemens Healthcare Headquarters Siemens AG Healthcare Sector Henkestrasse 127 91052 Erlangen Telephone: + 49 9131 84 - 0 Germany

www.siemens.com/healthcare

www.siemens.com/diagnostics

Your First Choice in Resistance DetectionMicroScan Gram Negative Conventional Panels

www.siemens.com/microbiology

Answers for life.

For more than 30 years, MicroScan® Systems have been exclusively focused on ID/AST testing, offering unmatched experience, expertise, and technical support to help guide physicians and improve patient care.

MicroScan Dried Overnight Gram Negative Panels from Siemens now continue a tradition of quality and innovation. They are designed to help keep your laboratory staff at the forefront of identification and susceptibility testing and are compatible with all MicroScan instruments.

• Provide clinically relevant identification from an extensive database of gram-negative microorganisms

• Confirm or screen for extended- spectrum beta-lactamases (ESßL) with routine panels

• Perform and interpret tests both manually or on MicroScan instrumentation

Global Division Siemens Healthcare Diagnostics Inc. 511 Benedict Avenue Tarrytown, NY 10591-5005 USA www.siemens.com/diagnostics

Versatility for your unique testing needs

Experience flexibility and choice through dynamic MicroScan menu options designed to streamline testing and help boost your efficiency.

• Manage changing formulary needs with a broad antimicrobic menu and more than 95 MicroScan panel choices (available globally)

• Select ID-only, AST-only, and ID/AST combination panels for workflow flexibility

• Utilize a one-panel format for all Siemens microbiology instruments for simplified testing procedures and streamlined workflow

Aligns with most EUCAST guidelines

Stay ahead of emerging resistance— the trusted way.

First-time accuracy The MicroScan system uses a growth-based, non-ID-dependent direct testing method, which allows for better detection of emerging resistance. The system does not rely on historical data: It provides a real-time advantage for accuracy and uses direct MIC* technology to detect emerging and low-level resistance. This means fewer confirmatory tests are needed, providing you with accurate results the first time. This functionality aligns with most CLSI guidelines to improve detection of resistance mechanisms without additional confirmation tests.

*Minimum inhibitory concentration

Panel Name Neg Combo 53

Neg Combo 58

Neg EN Combo 70

Neg NF Combo 71

Neg BP Combo 45

Neg BP Combo 46

Neg BP Combo 49

Neg/Urine Combo 56

Neg/Urine Combo 57

Neg/Urine Combo 59

Neg/Urine Combo 69 Neg MIC 39 Neg MIC 40 Neg MIC 44

SMN 10371524 10479100 10713832 10713833 10479095 10479104 10713834 10479092 10479098 10479101 10713831 10479097 10479105 10713830

Legacy Catalog Number B1016 – 142 B1016 – 158 B1016 – 177 B1016–178 B1016 – 153 B1016–162 B1016 – 179 B1016 – 150 B1016 – 156 B1016 – 159 B1016 – 176 B1016 – 155 B1016 – 163 B1016 – 175

Languages E, ES, GR, NO, PL, PT, TR

E, ES, GR, PL, PT

DE, E, ES, FR, GR, IT, PL, PT, TR

DE, E, ES, FR, GR, IT, PL, PT, TR

DE, E, GR, IT, NO, PL

DE, E, FR, GR, IT, NO, PL

DE, E, ES, FR, GR, IT, PL, PT, TR E, GR, NO, PL E, FR, NO E, ES, GR, PL, PT DE, E, ES, FR, GR,

IT, PL, PT, TR E, FR, NO DE, E, FR, GR, IT, NO, PL, PT

DE, E, ES, FR, GR, IT, KO, PL, PT, TR

Abbr. Antimicrobic Agent µg/mL µg/mL µg/mL µg/mL µg/mL µg/mL µg/mL µg/mL µg/mL µg/mL µg/mL µg/mL µg/mL µg/mL Abbr.

Ak Amikacin 8 – 32 8 – 32 8 – 32 8 – 32 8–16 8–16 16–32 8–16 8 – 16 – 8 – 16 4 – 16 8 – 16 8 – 32 AkAmx Amoxicillin – – – – – – – – 4 – 8 – – 1– 8 – – AmxAug Amoxicillin/K Clavulanate 8/4 – 16/8 – 8/4 – 16/8 – 8/4–16/8 2/1–8/4 – 2/1–8/4 4/2 – 8/4 8/4 – 16/8 4/2 – 16/8 2/1– 8/4 2/1 – 8/4 8/4 – 16/8 AugAm Ampicillin 8 – 16 – 8 – 16 – 8–16 2–8 8–16 2–8 – 8 – 16 8 – 16 – 0.5 – 8 8 – 16 AmA/S Ampicillin/Sulbactam – 4/2 – 16/8 – 8/4 – 16/8 – – 8/4–16/8 – – – – – 1/0.5 – 8/4 8/4 – 16/8 A/SAzt Aztreonam 1, 8 – 16 1– 16 – 1– 16 1, 8 – – 1, 8–16 1, 8 – 16 – – 1– 16 1, 8 – 16 1, 4 – 16 AztCfz Cefazolin 8 – 16 – – – 8–16 – – – – 8 – 16 – – – – CfzCpe Cefepime 1, 8 – 16 1– 16 1, 4 – 16 1, 4 – 16 1, 8 1, 4–8 8–16 1, 4–8 1, 8 1, 8 – 16 – 0.5 – 8 0.5 – 8 1– 16 CpeCfe Cefixime – – – – – – – – 1– 2 – – 1– 2 – – CfeCft Cefotaxime 1– 32 – 1– 16 8 – 32 1–32 1–2, 16 1–2, 8–32 1–2, 16 1– 2, 16 1– 32 1– 16 0.5 – 2, 16 0.5 – 2, 16 1– 32 CftCfx Cefoxitin 8 – 16 – 8 – 16 – 8–16 8 8 8 8, 32 8 – 16 8 – 16 2 – 8, 32 8 – 16 8 – 16 CfxCpd Cefpodoxime – – – – – 1 – – – – – – 0.5 – 1 – CpdCaz Ceftazidime 1, 4 – 16 1– 32 1– 8 1– 16 1, 8–16 1, 4–8 1, 4–16 1, 4–8 1, 4 – 8 1– 16 1– 16 0.5 – 8 0.5 – 8 1– 16 CazCax Ceftriaxone – – – – – – – – – – – – 0.5 – 2 – CaxCrm Cefuroxime 4 – 16 – 8 – 16 – 4–8 4–8 4–16 4–8 8 4 – 16 8 – 16 – 1– 8 4 – 16 CrmCf Cephalothin 8 – 16 – 8 – 16 – – – – 8 8, 32 8 – 16 – 8 – 32 – 8 – 16 CfC Chloramphenicol – – – – – 8 – – – – – – 8 8 – 16 C

Cp Ciprofloxacin 0.5 – 2 0.5 – 2 0.5 – 2 0.5 – 2 0.5–1 0.5–1 1–2 0.5–1 0.5 – 2 0.5 – 2 0.5 – 2 0.25 – 2 0.5 – 1 0.5 – 2 CpCl Colistin – 2 – 4 – 2 – 4 – 2–4 2–4 2–4 2 – 4 – – 2 2 2 – 4 Cl

Dor Doripenem – – – 1– 4 – – – – – – – 1, 4 1– 4 1– 4 DorEtp Ertapenem 0.5 – 4 – 0.5 – 1 – 0.5–1 0.5–1 0.5–1 0.5–1 0.5 – 1 0.5 – 1 0.5 – 1 0.5 – 1 0.5 – 1 0.5 – 1 Etp

Cft/CA ESßL Confirmation – Cefotaxime/ K Clavulanate 0.5/4 – 1/4, 4/4 – 0.5/4 – 1/4, 4/4 – 0.5/4,

4/4–8/4 0.5/4, 4/4 0.5/4, 4/4 0.5/4, 4/4 0.5/4, 4/4 0.5/4 – 4/4 0.5/4 – 4/4 0.5/4, 4/4 0.5/4, 4/4 0.5/4 – 4/4 Cft/CA

Caz/CA ESßL Confirmation – Ceftazidime/ K Clavulanate 0.25/4, 2/4 – 0.25/4, 2/4 – 0.25/4, 2/4 0.25/4, 2/4 0.25/4, 2/4 0.25/4, 2/4 0.25/4, 2/4 0.25/4 –

0.5/4,2/40.25/4 –

0.5/4, 2/4 0.25/4, 2/4 0.25/4, 2/4 0.25/4 – 0.5/4, 2/4 Caz/CA

Fos Fosfomycin – 16 – 64 – – 32 32 32 – 64 32 32 16 – 64 32 – 64 32 32 32 – 64 FosGm Gentamicin 2 – 8 1– 8 2 – 8 2 – 8 2 – 4 2 – 4 4 – 8 2 – 4 2 – 4 2 – 8 2 – 8 1– 4 2 – 4 2 – 8 GmImp Imipenem 1– 8 1– 8 1– 8 1– 8 2 – 8 2 – 8 1– 8 2 – 8 2 – 8 1– 8 1– 8 0.5 – 8 1– 8 1– 8 ImpLvx Levofloxacin – 1– 4 1– 4 1– 4 1– 2 1– 2 2 – 4 1– 2 – – 1– 4 – 1– 2 1– 4 LvxMec Mecillinam – – – – – – – 8 8 – – 8 – – MecMer Meropenem – 1– 8 1– 8 1– 8 2 – 8 2, 8 1 – 8 2 – 8 – – 1 – 8 – 0.5 – 8 1– 8 MerMin Minocycline – 4 – 8 – 4 – 8 – – – – – – – – – 4 – 8 MinMxf Moxifloxacin – – – – – 0.5 – 1 0.5 – 1 0.5 – 1 – – – – 0.5 – 1 – MxfNA Nalidixic Acid 16 – – – – – 16 16 8 – 16 16 16 8 – 16 – 16 NAFd Nitrofurantoin – – – – 32 – 64 64 32 – 64 64 64 32 – 64 32 – 64 64 64 32 – 64 Fd

Nxn Norfloxacin – – – – 0.5 – 1 0.5 – 1 – – 0.5 – 1 0.5 – 1 0.5 – 1 0.5 – 1 0.5 – 1 0.5 – 1 NxnOfl Ofloxacin – – – – – – – – 0.5 – 1 – – 0.5 – 4 0.5 – 1 – OflPi Piperacillin – – – 8 – 16, 64 8 – 16 4 – 16 16,64 8 – 16 – – – 8 – 16, 64 4 – 16 8 – 16, 64 Pi

P/T Piperacillin/Tazobactam 8 – 16, 64 8 – 64 8 – 16, 64 8 – 16, 64 8 – 16 4 – 16 16,64 8 – 16 8 – 16 8 – 16, 64 8 – 16, 64 4 – 16, 64 4 – 16 8 – 16, 64 P/TTe Tetracycline – – – – 4 – 8 4 – 8 4 – 8 – 4 – 8 – – – 4 – 8 4 – 8 TeTi Ticarcillin – 8 – 32 – 16, 64 – – – – 8 – 16 – – 8 – 64 – – Ti

Tim Ticarcillin/K Clavulanate – – – – – – – 8 – 16 8 – 16 – – 8 – 64 – – TimTgc Tigecycline 1– 2 0.5 – 2 1– 2 1– 2 1– 2 1– 2 1– 2 1– 2 1– 2 – – 1– 4 0.25 – 2 1– 2 TgcTo Tobramycin 2 – 8 2 – 8 2 – 8 2 – 8 2 – 4 2 – 4 4 – 8 2 – 4 2 – 4 2 – 8 2 – 8 1– 4 2 – 4 2 – 8 ToT Trimethoprim – – – – – 8 – 8 – – – – 8 – T

T/S Trimethoprim/Sulfamethoxazole 2/38 2/38 2/38 – 4/76 2/38 – 4/76 2/38 – 4/76 2/38 – 4/76 2/38 – 4/76 2/38 – 4/76 2/38 – 4/76 2/38 – 4/76 2/38 – 4/76 2/38 – 4/76 2/38 – 4/76 2/38 – 4/76 T/S

Total Antimicrobics/Panel 22 18 21 20 27 30 27 31 31 22 22 31 35 33

Panel DefinitionsNeg Combo: Provides gram-negative identification and susceptibility results on one panel. Drug selection provides both Enterobacteriaceae and Non-Enterobacteriaceae coverage, as well as systemic reporting.

Neg EN Combo (Neg Entero Combo Panel Type 70):† Provides gram-negative identification and susceptibility results on one panel. Drug selection provides Enterobacteriaceae coverage, as well as urine and systemic reporting.

Neg NF Combo (Neg Non-Entero Combo Panel Type 71):† Provides gram-negative identification and susceptibility results on one panel. Drug selection provides Non-Enterobacteriaceae coverage, as well as urine and systemic reporting.

Neg BP (Breakpoint) Combo: Provides gram-negative identification and susceptibility results on one Enterobacteriaceae and Non-Enterobacteriaceae coverage, as well as urine and systemic reporting. Panel contains shorter dilutions around the breakpoints, allowing for a broader drug menu.

Neg/Urine Combo: Provides gram- negative identification and susceptibility results on one panel. Drug selection provides both Enterobacteriaceae and Non-Enterobacteriaceae coverage, as well as urine and systemic reporting

Neg MIC panels: Provides gram-negative susceptibility results only and longer dilution schemes for better detection of emerging resistance. Drug selection provides both Enterobacteriaceae and Non-Enterobacteriaceae coverage, as well as urine and systemic reporting.

†Not for sale in the U.S., China, or Japan

Legend: DE – German E – English ES – Spanish FR – French GR – Greek IT – Italian NO – Norwegian PL – Polish PT – Portuguese TR – Turkish