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    Physiologic and Psychologic Changes During

    Pregnancy:

    1. Presumptive Signs- those that are least indicative of pregnancy,taken as single entities, they could easily

    indicate other conditions

    - largely subjective

    a. Breast changes

    b. Nausea and vomitingc. Amenorrhea

    d. Frequent urination

    e. Fatigue

    f. Uterine enlargementg. Quickening

    h. Linea nigra

    i. Melasma

    j. Striae gravidarum

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    MELASMA

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    Sstri

    STRIAE GRAVIDARUM

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    2. Probable Signs-

    a. Serum laboratory test

    hCG- a hormone created by the chorionic villi inthe placenta.

    *Reaches a measurable level (50mIU/ml) 7-

    9 days after conception

    *Peaks at about 100mIU/ml but by the 60th

    -80thday after this it declines again and is

    no longer detectable in the serum.

    b. Chadwicks Sign- color change of the vagina from pink

    to violetc. Goodellssign- softening of the cervix

    d. Hegarssign- softening of the lower uterine segment

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    CHADWICK S SIGN WITH LEUKORRHEA

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    e. Sonographic evidence of gestational sac

    f. Ballotement- when lower uterine segment istapped on a bimanual

    examination, the fetus can be

    felt to rise against theabdominal wall.

    g. Braxton Hicks contractions- periodic

    uterine tighteningh. Fetal outline felt by the examiner

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    3. Positive Signs

    a. Sonographic evidence of the fetal outline

    b. Fetal heart audible

    * 18-20 weeks of pregnancy audible by anordinary stethoscope 120-160 bpm

    c. Fetal movement felt by the examiner- 20th-24th

    weeks AOG

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    PsychologicaL Changes During Pregnancy

    1. Social Influences

    2. Cultural Influences

    3. Family Influences

    4. Individual Influences

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    The Psychological Tasks of Pregnancy:

    First Trimester: Accepting the pregnancy- spends time

    recovering from shock of learning they are

    pregnant and concentrate on what it feels like

    to be pregnant.

    Second Trimester: Accepting the baby- moves through

    emotions such as narcissism and introversion as they

    concentrate on what will happen and what it feels

    like to be pregnant.

    Third Trimester: Preparing for parenthood

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    EMOTIONAL RESPONSES TO PREGNANCY:

    1. Ambivalence- interwoven feelings of wanting and not wanting

    2. Grief

    3. Narcissism-reaction to self-intrusion; self centeredness

    4. Introversion vs. Extroversion

    5. Body Image and Boundary

    Body Image- the way your body appears to yourself

    Body Boundary- a zone of separation you perceive between yourself

    and objects or other people

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    6. Stress

    7. Couvade syndrome- men experiencing physicalsymptoms such as nausea,

    vomiting etc. to some degree or

    even more intensely than their

    partners do.

    8. Emotional lability

    9. Changes in sexual desire

    10. Changes in the expectant family

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    PHYSIOLOGIC CHANGES OF PREGNANCY

    A. Reproductive System

    A1. Uterine Changes- increase in length, depth, widthweight, wall thickness and

    volume

    12thweek- uterus is firm and sphenoid under the

    abdominal wall just above the

    symphysis pubis

    20th

    -22nd

    week- fundus is at the level of the umbilicus

    36thweek- fundus is at the level of the xiphoid process

    38th-40thweek- lowers

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    *Increase of blood flow to the uterus- pre-pregnancy- 15-20

    ml/min by the end of pregnancy- 500-750 ml/min 75 % of

    which is going to the placenta

    *Uterus is more anteflexed, larger, softer to touch than usual

    *6th week of pregnancy- lower uterine segment just above thecervix becomes soft (HegarsSign)

    * 12thweek of pregnancy- Braxton Hicks contractions begin

    *16

    th

    -20

    th

    week of pregnancy- Ballottment may be noted*20th-24thweek- fetal outline may be palpated

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    A2. Amenorrhea- due to suppression to FSH

    Other possible reasons: uterine infection,

    climate change, worry, chronic illness such assevere anemia or stress

    A3. Cervical Changes- becomes vascular and edematous

    - becomes soft in consistency (GoodellsSign) due to the high estrogen level

    Operculum- mucus plug which acts to seal out bacteria during

    pregnancy and to help prevent infection in the

    fetus and membranes.

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    A4. Vaginal Changes

    Estrogen- causes the vaginal epithelium and underlyingtissue becomes hypertrophic and enriched

    with glycogen.

    *Changes in color from pink to dark violet (Chadwicks

    Sign)

    *pH of vaginal secretions decreases from 7 to 4-5 due to

    the action of Lactobacillus acidophilus and Doderlein

    bacillus

    A5. Ovarian Changes

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    B. Breast Changes

    *Estrogen- causes a feeling of fullness, tingling sensation and

    tenderness* Hyperplasia of the mammary alveoli

    * Areola darkens and its diameter increases from about 3.5 cm

    to 5 or 7.5 cm (1.5-2-3 inches)

    *There is formation of secondary areola, increase in vascularity,

    blue veins become prominent over the surface of the breast,

    sebaceous glands of the areola (Montgomery tubercles)

    enlarge.

    *16th week of pregnancy- colostrums is expelled from thenipples in a form of thin watery fluid which is high in protein

    and considered to be a precursor of breast milk

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    SYSTEMIC CHANGES

    A. Integumentary System

    A1. Striae gravidarum- pink or reddish streaks appearing on the sides of the

    abdominal wall and sometimes on the thighs.

    A2. Diastasis- separation of rectus muscle, bluish grooveat the site of the

    separation

    *At the 28thweek AOG the depression of the umbilicus becomes

    obliterated and smooth.A3. Linea nigra- dark line running from the umbilicus to the symphysis pubis

    A4. Melasma/ chloasma or the mask of pregnancy

    A5. Vascular spiders- small, fiery-red branching spots commonly found on

    the thighs.

    A6. Increased perspiration

    A7. Palmar erythema- due to increased estrogen level in the body

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    B. Respiratory system

    * NO change in vital capacity

    * Tidal volume is increased by 30-40 %*Respiratory rate is increased by 1-2 cpm/minute (18-

    20cpm/min)

    * Residual volume- decreased by 20 %

    * Plasma PCO2- decreased by 27-32 mHg

    * PlasmaO2- increased to 104-108 mmHg

    * Blood pH- increased to 7.40-7.45

    *Respiratory minute volume- increased by 40%* Expiratory reserve- decreased by 20%

    *Increased ventilation

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    D. Cardiovascular System

    D1. Blood volume increases by at least 30% and

    possibly as much as 50%

    Normal blood loss for NSVD- 300-400 ml

    Normal blood loss for CS- 800-1000 ml

    * The increase in blood volume peaks at the 28th-32nd

    week

    D2. Iron needs- 800 mg during pregnancy

    True anemia- either a hemoglobin concentration of

    less than 11.5 g/100 ml or a Hct of less than 30 %

    D3. Folic acid- helps in preventing neural tube defects

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    D4. Heart- increase in cardiac output by 25-50%

    HR increases by 10 bpm

    *Innocent heart murmurs may be heard r/t altered heart

    position and decreased blood viscosity.* Palpitations are also common due to the stimulation of

    SNS

    D5. Regional blood flow- impaired to the lower extremities

    D6. BP- does not normally rise

    D7. Supine hypotension syndrome- light headedness,faintness and palpitations

    Interventions: lie on the left side and rise from bed slowly

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    D8. Blood Constitution

    *Increase in circulating fibrinogen (as much as

    50 %) due to increased level of estrogen

    *Increase in clotting factors VII, VIII, IX, and X

    and platelet count

    *Increase in WBC* Decrease in total protein which may be a

    cause of ankle edema

    *Increase in body lipid by 1/3 and cholesterolby 90-100%

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    E. Gastrointestinal system

    *Slow intestinal peristalsis and emptying of the

    stomach

    *heartburn, constipation andf flatulence is common

    *Nausea and vomiting is common due to increase l

    level of hCG and progesterone or as a

    systemic reaction to the increased level of estrogenand decreased level of glucose.

    *Subclinical jaundice may be experienced

    *Hypertrophy of the gumlines and possible bleeding

    of the gingival tissue*Decreased pH in the mouth

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    F. Urinary System

    *Glomerular filtration rate- increased by 50 %* Renal plasma flow- increased by 25-80 %

    * BUN- decreased by 25%

    * Plasma creatinine level- decreased by 25%

    * Renal threshold for sugar- decreased to allowspillage

    * Bladder capacity- increased by 1000 ml

    * Diameter of ureters- increased by 25%

    * Frequency of urination- increased in the 1sttrimester and the last two weeks of

    pregnancy to 10-12 times/day

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    ANKLE EDEMA

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    G. Skeletal System

    * Ca and Ph needs are increased

    * There is softening of pelvic ligaments and joints which

    causes the waddling gait

    H. Endocrine System

    *Placenta- produces hCG, estrogen, progesterone, hPL,

    relaxin and prostaglandinsEstrogen- causes breast changes and palmar erythema

    Progesterone- maintains endometrium inhibiting uterine

    contractions;aids in the preparation of the

    breasts for lactation.Relaxin- secreted primarily by the corpus luteum

    - inhibits uterine contractions; softens the cervix

    and the collagen in joints

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    hCG- secreted by the trophoblast in the placenta

    stimulates estrogen and progesterone synthesis until the

    placenta can take its role.hPL- also known as human chorionic somatomammotropin hormone

    - serves as the antagonist to insulin, freeing fatty acids for

    energy

    Prostaglandin- affects smooth muscle contractility to such an

    extent they may be the trigger that initiates labor at

    term

    *Pituitary gland- halted FSH and LH release because of increased

    levels of estrogen and progesterone

    - late in pregnancy it produces oxytocin

    - produces prolactin which prepares the breasts for

    lactation

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    *Thyroid and parathyroid glands- glands enlarges and

    BMR increases by 20%

    *Protein based-iodine, butanol-extractable iodine,and thyroxine are all elevated as well.

    * Adrenal glands- increased function due to increased

    level of corticosteroid and

    aldosterone.

    - aids in suppressing inflammatory

    reaction , helps in regulating theglucose metabolism in the woman

    Increase in aldosterone aids in promoting sodium

    reabsorption

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    Estimating Pelvic Sizepelvic pelvimetry and fetal

    sonography

    *Estimation should be done at least by the 24thweek ofpregnancy because by this time there is danger that the fetal

    head will reach a size that will interfere with safe passage

    and birth if pelvic measurements are small

    TYPES OF PELVES:

    1. Android

    2. Anthropoid

    3. Gynecoid

    4. Platypelloid

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    Common Measurements:

    1. Diagonal conjugate- distance between the anterior

    surface of the sacralprominence and the anterior

    surface of the inferior margin of

    symphysis pubis

    -considered to be the most usefulmeasurement for the estimation

    of pelvic size.

    -suggests the anteroposterior

    diameter of the pelvic inlet* Measured while the client is in a lithotomy position

    >12.5 cm- adequate for childbirth (average fetal head

    is 9 cm)

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    3. Ischial tuberosity diameter- distance

    between the ischial tuberosity or thetransverse diameter of the outlet. Made

    at the medial or lowermost aspect of the

    ischial tubersities at the level of the anus(11 cm)

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    LEOPOLDS MANEUVER

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    LEOPOLDS MANEUVER

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    DISSCOMFORTS DURING THE FIRST TRIMESTER

    1. Breast Tenderness

    2. Palmar Erythema

    3. Constipation

    4. Nausea Vomitting and Pyrosis

    5. Fatigue

    6. Muscle cramps- due to decreased Calcium and increased Phosphorus

    7. Hypotension

    8. Varicosities- Let client rest in Simsposition or with legs raised for 15-20

    min 2x a day

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    9. Hemorrhoids- modified Simsposition or knee chest position

    for 10-15 min.

    -apply Witch hazel or cold compress to relieve

    pain

    10. Heart palpitations

    11. Frequency of urination- reduce caffeine intake and practiceKegelsexercise

    12. Abdominal discomfort

    13. Leukorrhea- a whitish vaginal discharge or increased vaginal

    secretions brought about by increased

    estrogen level and blood supply to the vaginal

    epithelium and cervix.

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    DISCOMFORTS DURING MIDDLE AND LATE

    PREGNANCY

    1. Backache- Pelvic rocking and tilting exercise

    2. Headache

    3. Dyspnea

    4. Ankle edema

    5. Braxton Hicks Contractions

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    Danger Signs of Pregnancy:

    1. Vaginal bleeding

    2. Persistent vomiting

    3. Chills and fever

    4. Sudden escape of clear fluid from the

    vagina

    5. Abdominal or chest pain

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    6. PIH

    6a. rapid wt. gain (over 2 lbs/week in the 2nd

    trimester and 1lb/week in the 3rdtrimester)

    6b. Swelling of the face and the fingers

    6c. Flashes of light or dots before the eyes6d. Dimness or blurring of vision

    6e. Severe continuous headache

    6f. decreased urine output

    7. Increased or decreased fetal movement

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    VARICOSITIES

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    HEMORRHOIDS

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    ELASTIC STOCKINGS

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    LEFT SIDE LYING POSITION

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    SQUATTING

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    TAILOR SITTING

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    PREVENTION OF EXPOSURE TO

    TERATOGENSTeratogen- any factor, chemical

    and physical thatadversely affects the

    fertilized ovum,

    embryo or fetus.

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    Maternal Infection

    TO- TOxoplasmosis

    * a protozoan infection spread through uncooked

    meat, and through handling cat stool in soil or cat

    litter.

    * Effect to fetus: CNS damage, hydrocephalus,

    microcephaly, intracerebralCalcification and retinal deformities.

    *Dx: Serum analysis

    *Tx: sulfonamides- but this can lead to increased

    bilirubin in the newbornPyrimethamine- antiprotozoal drug but an

    antifolic acid drug at the

    same time

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    R Rubella

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    R- Rubella

    *otherwise known as German measles

    *Effect to fetus: deafness, mental or motor

    challenges, cataract, cardiac

    defects (PDA or pulmonary

    stenosis), retarded

    intrauterine growth,thrombocytopenic purpura,

    dental and facial clefts.

    *Dx. Rubella titer- > 1:8 suggests immunity< 1:8 susceptible to viral

    invasion

    Greatly increased- suggests recent infection

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    RUBELLA

    C- Cytomegalovirus (CMV)

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    C- Cytomegalovirus (CMV)

    * a member of the herpes virus family

    *MOT: Droplet

    * Effect to the fetus: neurologically

    challenged (hydrocephalus, microcephaly

    spasticity with eye damage [optic atrophy

    and chorioretinitis]) deafness, chronic liverdisease, skin covered with large petechiae

    (blueberry muffin lesions)

    *Dx. Isolation of CMV antibodies in theserum

    * No treatment

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    CHILD AFFECTED WITH CMV

    H- Herpes simplex

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    H Herpes simplex

    *1sttrimester- congenital anomalies or

    spontaneous miscarriage

    *2nd or 3rd trimester- premature birth, intrauterinegrowth retardation and

    continuing infection

    Other viral infection

    RubeolaCoxsackievirus

    Mumps

    Varicella (chickenpox)

    Poliomyelitis

    Influenza

    Viral hepatitis

    Parvovirus B19- causative agent of Erythema infectiosum (5th

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    Parvovirus B19 causative agent of Erythema infectiosum (5

    dise. ) attacks the RBC

    -associated with fetal death in early pregnancy

    and anemia and congenital heart defect in late pregnancy

    Syphylis- caused by Trepenoma pallidum

    *causes damage to the fetus after the 16th-18thweek of

    intrauterine life when the cytotrophoblastic layerof the

    placental villi has atrophied* causes deafness, cognitive challenge, osteochondritis and

    death

    *Dx. VDRL and rapid plasma regain- remains high for more than

    2oo days*infants born of a mother with syphilis- remains to be (+) up to

    3 mos. even if the dse has

    already been treated.

    *Tx. Benzathine penicillin

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    SYPHILIS

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    Lyme disease- Borrelia burdorferi

    *Tx. Tetracycline or doxycycline-

    not safe for pregnant womenPenicillin- drug of choice

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    TRICHOMONIASIS & VAGINITIS

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    AMELIA

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    PHOCOMELIA