lapkas mata-keratitis numularis.doc
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CHAPTER II
LITERATURE REVIEW
". C#$%&"
Cornea is clear avascular anterior part of the eyes. Cornea consist of five
layers (epithelium, bo man's membrane, stroma, decemet membrane, and
endothel). Cornea is the part of visual a is ith the greatest refractive inde , so
any abnormality of this part of the eyes, especially in centre part, ill greatly
disturb the visual acuity.
ince the cornea is avascular, it is nourished by tear, a*ueous humour, and
pericorneal blood vessels.
&phitelium
o +he outmost layer of cornea ith - um thickness, consist of
layers of nonceratini ed s*uamous epithelial.
o Provide primary protection to the deeper layer of cornea from outer
environment and selectively inhibits transport of ater and
electrolyte.
o +his part can regenerate perfectly after in/ury
0o man membrane
o "nterior part of stroma
o 1nable to regenerate
troma
o +he thickest layer of cornea
o Consist of ell arranged fine collagen fiber
2ecement membrane
o Produced by endotel
o trongest layer in cornea
o &lastic
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&ndothel
o
4onolayero +he most important part in hydration of cornea
o 1nable to regenerate
o 2amage to this part can cause corneal edema
Cornea innervated by ophthalmic branch of +rigeminal %erve. +his branch
terminates in second layer of epithelium. In/ured nerve in cornea can heal in 5
months.
0. K&$"+I+I
Keratitis is an inflammatory process in cornea. Keratitis is classified based
on location of lesion in corneal layer and cause6
0ased on location6
!. uperficial keratitis6
&pithelial keratitis (flouresence test 7)
o Keratitis pungtata superficialo Keratitis 8erpes simpleks
o Keratitis 8erpes oster
ubepithelial keratitis (flouresence test 9)
o %ummular keratitis of 2immer
o 2isiform keratitis of Westhoff
tromal keratitis (flouresence test 9)
o %europaralitik keratitis
o Keratitis et lagoftalmus
3. Profound Keratitis6
Keratitis Interstitial
Keratitis klerotikans
Keratitis 2isiformis
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0ased on cause6
0actery6 2iplococcus pneumonia, treptococcus hemolyticus,
Pseudomonas aeroginosa, etc
:irus 6 8erpes simpleks, 8erpes ooster, etc
fungi 6 Candida, "spergillus sp.
"llergic reaction
"vitaminosis "
%.: damage
2irect trauma
2ry eye
Patophysiology
ince the cornea is avascular, inflammatory process ill not as effective
and immediate as other ell vasculari ed tissues. Wandering cell in corneal
stroma ill be the first immunologic cell hich response to inflammatory process.
It ill become tissue macrophage. +his process ill then follo ed by
vasodilatation of blood vessels in limbus (this ill be seen as pericorneal
in/ection). Infiltration of P4%, macrophages, and plasma cell ill cause cornea
looks cloudy.
Corneal epithelium can be destroyed and form ulcer. uperficial ulcer ill
resolve perfectly, but the deeper one ill leave scar. If the iris involved in this
inflammatory response, inflammatory cell ill be accumulated in anterior
chamber and can be seen as hypopion.
ymptoms of keratitis include, but are not limited to6
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+earing
Pain
ensitivity to light
Inflammation of the eyelid
2ecrease in vision
$edness.
C. %1441halo? appearance. It is usually caused by
viral invasion to epithelial layer of cornea secondary to trauma in cornea.
$eplication of virus in epithel follo ed by spread of to in to stroma causes
subepithelial infiltrate formation. +his type of keratitis usually happens unilateral.
%ummular keratitis
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CHAPTER III
CASE
!. Patient identity
%ame 6 4s. 4
e 6 =emale
"ge 6 !- years old
"ddress 6 ungai Purun 0esar
&thnic 6 4elayu
@ob 6 9 (student)
$eligion 6 4oslem
Patient as e amined on "pril !; th, 3-!!
3. "namnesis
a. 4ain complaint6 hitish spots on left eye.
b. 8istory of disease 6
Patient complain ithish spots on left eye hich is painless. =our months
ago patient has her left eye entered by bug. =or about one eek she felt
slight pain, tearing, and redness in her left eye. When the symptoms
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resolved, her mother reali ed that some ithish spots formed in her left
eye. Patient complain no blurry vision since then.
c. Past clinical history6 Patient claims that there is no history of the same
symptoms before.
d. =amily history 6 +here are no one of her family have the same complaint.
5. Beneral Physical "ssessment
Beneral condition 6 good
" areness 6 composmentis
:ital igns6
8eart $ate 6 - Dminute
$espiration fre*. 6 ! Dminute
0lood Pressure 6 !--DA- mm8g
+emperature 6 5A,E oC
;. #phthalmological status
:isual acuity6
a. #2 6 ADA
b. # 6 ADA
$ight eye
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ptosis (9), lagoftalmos
(9), edema (9)
Palpebra ptosis (9), lagoftalmos
(9), edema(9)
$edness (9), discharge
(9), in/ection(9)
Conjungtiva $edness (9), discharge
(9), in/ection(9)
Clear, edema ((9) Cornea Clear, edema (9),
in iltrate !"#
clear, deep COA Clear, deep
Iris colour 6 bro n
Pupil6 circular, isokor,
reactive to light
Iri$ an% pupil Iris colour 6 bro n
Pupil6 circular, isokor,
reactive to light
Clear Len$ Clear
Clear Vitreou$ Clear
%ormal &un%u$ %ormal
&ye ball movement
hado test 6 positive for both eye
Ishihara test 6 not measure
++
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+
+
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OD OS
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:isual field test (confrontation) 6 normal
&loure$en'e te$t( not 'on%u'te%
. $esume
Patient complains painless hitish spots on her left eye. =our months
ago patient has her left eye entered by bug that cause slight pain, redness and
tearing hich resolved in a eek. Patient complains no blurry vision.
:ital signs of this patient are in normal range. :isual acuity of both
eyes are ADA. &yelids are normal. Cornea of the left eye has some hitish
grouped coin shaped spots. +he anterior chamber, lens, and vitreous body of
both eyes are clear. Iris and pupil look normal. +he flourosence test as not
conducted because patient's mother refused.
A. 2iagnose
Working 2iagnose6
%ummular keratitis #
E. Plan for e amination
9 =louresence test
. +reatment6
9 %on medicamentous6 using of protective glasses
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9 4edicamentous6
o Bentamycin eye drop -,5G ;9A ! gtt
o Prednisolon eye drop -, G 39; !gtt
F. Prognosis
#2
"d vitam 6 bonam
"d functionam 6 bonam
"d sanactionam 6 bonam
#
"d vitam 6 bonam
"d functionam 6 bonam
"d sanactionam 6 bonam
CHAPTER IV
DISCUSSION
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" girl, !- years old complained hitish spots in her left eyes. +here
as history of bug entered her left eye four months ago. he felt slight pain,
tearing, and redness for about one eek. 8er mother then reali ed that some
hitish spots formed in her cornea.
+he only abnormality found in physical e amination is the hitish
grouped coin shaped spots in patient left eye. =rom anamneses there is history of
bug entered the eye. In this case it can cause trauma hich is possibly follo ed by
secondary viral infection to the epithelial lining of cornea. Infiltration that
happens in subepithelial layer cause the coin shaped spots appearance.
Working diagnose of this patient is nummular keratitis based on the
appearance of corneal abnormality.
$ecommended therapy for this patient includes nonmedicamentous
such as earing protective glasses to prevent recurrent trauma. 4edicamentous
therapy for this patient aims to prevent secondary bacterial infection ith
antibiotic (gentamycin) and to reduce inflammatory process ith corticosteroid
(prednisolone).
C8"P+&$ :
C#%C
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" girl !- years old ith complaint of hitish painless grouped coin shaped
spots in the left eyes and history of eye trauma. Working diagnose for this patient
is nummular keratitis. +he therapy included non medicamentous ( earing
protective eye glasses) and medicamentous (gentamycin and prednisolone eye
drop).
$&==&$&%C&
Ilyas, . 3--E. Ilmu Penyakit Mata edisi ketiga . @akarta6 0alai Penerbit =K1I.
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hann, =. 3-- . Drug Doses . ! th edition.
:aughan 2B, et al. 3---. Oftalmologi umum edisi 14 . @akarta6 Widya 4edika.
!5