8/6/2019 LAL0108 Low Res

1/48

Life after liver transplant

Fighting liver disease

8/6/2019 LAL0108 Low Res

2/48

2

l

l

l

l

Life after liver transplant

0800 652 7330

www.britishlivertrust.org. uk

8/6/2019 LAL0108 Low Res

3/48

Fighting liver disease 3

Contents

8/6/2019 LAL0108 Low Res

4/48

4

l

l

l

l

l

l

l

l

l

l

l

The liver

8/6/2019 LAL0108 Low Res

5/48

Fighting liver disease 5

How liver disease develops

8/6/2019 LAL0108 Low Res

6/48

6

8/6/2019 LAL0108 Low Res

7/48

Fighting liver disease 7

Looking ahead

8/6/2019 LAL0108 Low Res

8/48

8

Immunosuppression

Rejection

8/6/2019 LAL0108 Low Res

9/48

Fighting liver disease 9

What are the warning signs o rejection?

l

l

l

l

l

l

8/6/2019 LAL0108 Low Res

10/48

10

What are the side eects o immunosuppression?

l

l

l

l

l

How does immunosuppression work?

8/6/2019 LAL0108 Low Res

11/48

Fighting liver disease 11

Medications

8/6/2019 LAL0108 Low Res

12/48

12

Ive heard I cant drink graperuit juice, is that true?

8/6/2019 LAL0108 Low Res

13/48

Fighting liver disease 13

Ten tips or taking your medication:

8/6/2019 LAL0108 Low Res

14/48

14

Side effectsNote: This is a list of potential side effects only

Not all side effects associated with these medications

are experienced by all people

You should report all side effects to medical staff

promptly

Cyclosporin(Neoral)

Calcineurin inhibitor

(CNI)

capsules/tablets/liquid

dont take with grapefruit

never to be given withtacrolimus

do not take before blood

tests at outpatient clinic

Tacrolimus(Prograf)

Calcineurin inhibitor

(CNI)

capsules

dont take with grapefruit

never to be given withcyclosporin

do not take before blood

tests at outpatient clinic

Kidney damage (nephrotoxicity) l l

High blood pressure (hypertension) l l

Headache l l

Tremors l l

Tingly hands and/or feet l l

Hyperglycaemia l lUpset stomach or nausea l l

Increased hair growth l

Thickening of the gums l

Diarrhoea or constipation l

Skin rash l

Hair loss or thinning l

Insomnia l l

Mental confusion l l

Sensitivity to sunlight l lGout l

Increase in cholesterol l

Impaired wound healing

Acne

Fluid retention

Feelings of anxiety

Lack of concentration

Moodswings

Weight gainDiabetes/increased blood sugar levels l

Increased risk of infection

Eye changes or visual problems l

Softening of the bones

Liver abnormality

Mouth ulcers

Aching joints l

Increased appetite

Thinning of the bones (osteoporosis)Fragile skin

8/6/2019 LAL0108 Low Res

15/48

8/6/2019 LAL0108 Low Res

16/48

16

Inection

Common inections ollowing transplantation

8/6/2019 LAL0108 Low Res

17/48

Fighting liver disease 17

8/6/2019 LAL0108 Low Res

18/48

18

How do I know I have an inection?

l

l

l

l

l

What can I do to prevent inection?

l

l

l

l

8/6/2019 LAL0108 Low Res

19/48

Fighting liver disease 19

l

l

l

l

l

l

l

l

What vaccines should I be given?

How can I avoid ood poisoning inections?

8/6/2019 LAL0108 Low Res

20/48

20

l

l

l

l

l

l

l

l

l

l

Can I take antibiotics or my inection?

Renal impairment

What causes renal impairment?

8/6/2019 LAL0108 Low Res

21/48

Fighting liver disease 21

l

l

l

l

l

l

l

l

Other known CKD actors are obesity and smoking

8/6/2019 LAL0108 Low Res

22/48

Malignancy

Lymphoprolierative disease

Skin cancers

22

8/6/2019 LAL0108 Low Res

23/48

Fighting liver disease 23

Cervical cancer

Colorectal carcinoma

Oropharyngeal carcinoma

Hepatocellular carcinoma (HCC)

8/6/2019 LAL0108 Low Res

24/48

24

Cardiovascular risks

l

l

l

l

l

l

8/6/2019 LAL0108 Low Res

25/48

Fighting liver disease 25

Diabetes

8/6/2019 LAL0108 Low Res

26/48

26

Viral hepatitis

Hepatitis C (HCV)

8/6/2019 LAL0108 Low Res

27/48

Fighting liver disease 27

l

l

l

l

Liestyle issues

8/6/2019 LAL0108 Low Res

28/48

28

Alcohol

Alcohol use was not the cause o my liver disease can I still

drink?

8/6/2019 LAL0108 Low Res

29/48

Fighting liver disease 29

I have had alcohol related liver disease can I still drink?

l

l

l

8/6/2019 LAL0108 Low Res

30/48

30

What about shandy or alcohol ree drinks surely they cant

hurt?

l

l

l

l

l

How can I manage without drinking alcohol?

8/6/2019 LAL0108 Low Res

31/48

Fighting liver disease 31

l

l

l

l

l

l

l

8/6/2019 LAL0108 Low Res

32/48

32

l

l

l

l

8/6/2019 LAL0108 Low Res

33/48

Fighting liver disease 33

Can I use illicit drugs ater transplant?

Surely cannabis is OK?

I am on a methadone programme. Should I stop it?

8/6/2019 LAL0108 Low Res

34/48

34

Alcohol and drug misuse

Alcohol Concern

8/6/2019 LAL0108 Low Res

35/48

Fighting liver disease 35

www.downyourdrink.com

www.drinkaware.co.uk

Drinkline (The National Alcohol Helpline)

Frank (ormerly the National Drugs Helpline)

Narcotics Anonymous (NA)

Alcoholics Anonymous (AA)

8/6/2019 LAL0108 Low Res

36/48

36

Living everyday lie

Diet ater liver transplant

When can I go back to my usual routine?

When can I take up exercise?

8/6/2019 LAL0108 Low Res

37/48

Fighting liver disease 37

What about travel?

8/6/2019 LAL0108 Low Res

38/48

38

Will I be able to have a normal sex lie ater liver

transplantation?

Can I have a baby ollowing liver transplantation?

8/6/2019 LAL0108 Low Res

39/48

Fighting liver disease 39

Planning ahead

Complementary and alternative medicines

8/6/2019 LAL0108 Low Res

40/48

40

Useul words

Acute

Anaemia

Autoimmune disease

Bile

Chronic

Cirrhosis

Creatinine

DNA

8/6/2019 LAL0108 Low Res

41/48

Fighting liver disease 41

Fibrosis

Glomerular ltration rate (GFR)

HBIG

Hyperlipidemia

Infammation

Intravenous

Liver unction tests (LFTs)

Lymphocyte

Lymphoprolierative

8/6/2019 LAL0108 Low Res

42/48

42

Malignant

NASH

Portal hypertension

Prophylaxis

8/6/2019 LAL0108 Low Res

43/48

Fighting liver disease 43

Who else can help?

Support groups

Liver Transplant Support

UK Transplant

8/6/2019 LAL0108 Low Res

44/48

44

Transplant Support Network (TSN)

Live Lie Then Give Lie

The Transplant Trust

8/6/2019 LAL0108 Low Res

45/48

Fighting liver disease 45

Further inormation

l

l

l

l

l

l

l

l

l

l

Special thanks

8/6/2019 LAL0108 Low Res

46/48

46

Can you make a dierence?

Friend o the British Liver Trust

Call us on

0800 652 7330

Email us at

ino@britishlivertrust.org.uk

Make a donation via our website at

www.britishlivertrust.org.uk

or write to

British Liver Trust

8/6/2019 LAL0108 Low Res

47/48

Fighting liver disease 47

I enclose a cheque/postal order made payable to the British

Liver Trust

I wish to pay by credit card:

MasterCard Visa CAF CharityCard

Please debit my card with the sum o .............................

Card No. ................................................................................

Expiry date ............................................................................

Name ......................................................................................

Address .................................................................................

................................................Postcode ...............................

Telephone ..............................................................................

Email ......................................................................................Signature ...............................Date .......................................

8/6/2019 LAL0108 Low Res

48/48

British Liver Trust

Tel: Fax:

Email:

Web: