hiv and aids. immune system overview hiv lives in these cells
Post on 22-Dec-2015
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• provirus stage lives inside cell, integrated with cell’s genome
• virion is particle that moves from cell to cell. In case of HIV, lives in blood and other body fluids:
– blood: 1000-100,000 virions per ml – Semen: 10-50 virions per ml– Saliva, vaginal secretions—lower
concentrations
Importance of HIV as case study
3. Environment of viruses:
• Epidemiology of spread of AIDS
Importance of HIV as case study
3. Environment of viruses:
In U.S., new cases down throughout 1990’s, now on rise again—why?
• Complicated because HIV infects cells of immune system
• HIV doesn’t kill, just lowers body defenses as T-cell levels drop
Importance of HIV as case study
4. Immune Response: