Health & Social CareIndustrial Innovation

Mr Andrew FowlieScottish Government

Health Innovations TeamSHINE North Sea Region Program 2014 2020

Imaging

Non Imaging Diagnostics

In VitroDiagnostics

Surgical & Clinical

EquipmentTherapeutic

Devices -Active

Therapeutic Devices -PassiveDigital

Health & Care

Science , Clinical &

Technology

Scotlands Medical Technologies Landscape

http://www.vascutek.com/http://www.aurumbiosciences.com/about-us/

Areas of Strength

Connected Healthcare

Precision Medicine

Pharma Services

Medical Technologies

Regenerative Medicine

Animal Health

Areas of Strength

Scotland hosts one of the most sizeable Life Sciences clusters in Europe

Pharmaceutical Services in Scotland % of Pharmaceutical Services Sector by

Company

1111

13

1822

14

713

Drug Discovery

Pre Clinical CRO

Clinical CRO

Pharmaceutical ManufactureSpecialist Product

Specialist Service

Clinical Trials Support

Statistical, Regulatory, Logistics & Quality

Over 150 companies, employing more than 9,000people with a turnover of 1.2 bn

A comprehensive supply chain supporting every stage of drug discovery, development and manufacturing

Refined testing and manufacturing expertise in fast-growing antibody-drug conjugate (ADC) market

Global leaders in pharmaceutical manufacture AMRI, BASF, Capsugel, GSK and SAFC recognize the advantages of operating in Scotland

Preferred clinical trial site for Pfizer, PPD, Quintiles and Roche

Responsive tissue acquisition and data linkage

Pharmaceutical Services in Scotland

Chart1

11

11

13

18

22

14

7

13

Revenue Shares by Subsectors

Sheet1

Revenue Shares by Subsectors

Drug Discovery11

Pre Clinical CRO11

Clinical CRO13

Pharmaceutical Manufacture18

Specialist Product22

Specialist Service14

Clinical Trials Support7

Statistical, Regulatory, Logistics & Quality13

Strengths of Medical Technologies in Scotland

% of Medtech Sector by Company Over c250 companies employing over 9,000 people and with a turnover of 1.2bn

Comprehensive medtech supply chain - c100+ companies, with capabilities in design, prototype and manufacture

Strong history of healthcare innovation

Ideal testing environment for the development of new medical technologies & diagnostics with NHS facilitated access to patients & professionals

Global leaders in medtech manufacture J&J, Medtronic, Terumo, Toshiba, Nikon, Ossr recognise the advantages of operating in Scotland.

Fast and supportive regulatory system

8%8%

12%

13%

3%6%

15%

12%

23%

Imaging

Non Imaging Diagnostics(exc in vitro diagnostics)In vitro Diagnostics

Surgical Instruments andOther Clinical EquipmentResearch Equipment

Active / Drug DeliveryTherapeutic DevicesPassive TherapeuticDevicesPersonal Care / AssistedLiving

Strengths of Medical Technologies in Scotland

Scotlands Precision Medicine LandscapeScotlands Precision Medicine Landscape

Improving Quality, Reducing Costs

1 2 3 4 5

QUALITY INITIATIVES COST REDUCTION PROGRAMMES

Costs more cost neutral improves quality quality neutral reduces qualityreduces costs

Connected and Distributed Care Models

New Models of Care:

Accelerating the Pace of Change

Business Opportunities

Technology Barriers

1100 known mobile apps available that may support people with diabetes

2% of people use them 40% Smart Phone use in Scotland Low level of health use of technology for remote support

Technology Barriers

1. Fears around privacy (e.g. of patients own data) and regulation;2. Perceived or real difficulty in achieving clinical benefit;3. Perceived or real difficulty in achieving economic benefit;4. Poor integration with health care processes;5. The apparent existence of too many mobile options available with limited evidence behind them, making it difficult for patients to know which, if any, would be useful.

Convergence

mobile computing (smart phone as a diagnostic tool/ body worn /in vitro monitoring)

digital manufacturing (3d printing etc) robotics (surgery, dispensing, devices etc) artificial intelligence (anticipatory care, forecasting,

informed decision making etc) networks & sensors (remote ECG, cloud enabled care etc) systems biology (regenerative medicine, genomics etc)

Policy and Resources

1. Core Health and Social Care Delivery Plan and usual range of support plans

2. Economic Plan- Innovation and Productivity-Scottish Government- CAN DO

3. UK Industrial Strategy4. Post BREXIT Emerging Policy

Innovation Supply Process

Registration Health Technology Assessment (HTA) Implementation

National /local procurement

Registration and Signposting

Industry/Enterprise input

Link to NHS/Social Care

Support for IMTO process

Early engagement and advice

Key stages of an innovation process for Scotland include the following;

Links to Network,

Performance and Delivery

HIAP Innovation stakeholders

SHTG

Demand Led - Open Innovation

THE KEY DRIVER OF INNOVATION IS SOLVING CUSTOMER PROBLEMS THOUGH CONTRACTS IN A

BUSINESS ENVIRONMENT

Creating Markets for Things that Dont Exist

David Connell

Cambridge University Centre for Business Research

OPEN INNOVATION

The process of innovating with others for shared risk and reward to produce mutual benefits for each

organisation, creating new products, processes or ideas that could not otherwise have been achieved

alone, or enabling them to be achieved more quickly, cheaply or efficiently

Vision:Build our life science industry into a global hub

that makes the UK the home of clinical research and medical innovation

A globally-unique and internationally competitive life sciences ecosystem supported by collaboration across industry, the NHS, academia and research funders to delivering health and wealth

Ensuring the UK has the talent and skills to underpin future life sciences success

SKILLS

Building on the Accelerated Access Review, enabling the

NHS to embrace cost-effective innovations for patients

Supporting collaboration on real world evidence, enabling

innovators and the NHS to research new technologies

Building on strengths in discovery research and

supporting translation of our world-class science base

Enabling SME growth and supporting infrastructure

across the regions of the UK

NHS DIGITALSCIENCE GROWTH

Health Advanced Research Programme: Bringing together a coalition of funders to anticipate a future vision of healthcare and create new industries in the UK based on grand challenges, such as healthy ageing, diagnosis-led healthcare, and AI

A joint programme of delivery between industry, NHS and Government to monitor and oversee implementation will be agreed through a Life Sciences Sector Deal

Working with the best global partners and driving new opportunities for trade and investment

GLOBAL BRITAIN

REGULATION

Securing patient safety and delivering the best ecosystem for life sciences

An industry-led vision for the life sciences sector that will be underpinned by new investment and create the foundations to support growth and attract new industries into the UK in the post-Brexit environment

Life Sciences Industrial Strategy

Our partnership

13/10/2017 Slide 32

Health & Social CareIndustrial InnovationDianummer 2Scotlands Medical Technologies LandscapeAreas of StrengthPharmaceutical Services in ScotlandStrengths of Medical Technologies in ScotlandScotlands Precision Medicine LandscapeDianummer 8Dianummer 9Dianummer 10Dianummer 11Dianummer 12Dianummer 13Dianummer 14Dianummer 15Dianummer 16Dianummer 17Dianummer 18Dianummer 19Technology BarriersTechnology Barriers Convergence Dianummer 23Policy and ResourcesDianummer 25Innovation Supply ProcessDianummer 27Demand Led - Open InnovationOPEN INNOVATIONDianummer 30Life Sciences Industrial StrategyOur partnership