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Dear friends,readers,supporters I hope you all are doing great, first of all I would like to say thanks for successful completion of this year of Microbioz India and by the end of this year Microbioz team going to complete its three successful year.We are going to launch our annual edition with Cover story entitled by: “Boost your brain power with microbes “.The cover story explains how does healthier microbes helps in boosting our brain strength.

TRANSCRIPT

Page 1: December 2015 issue of Microbioz India
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ear friends,readers,supporters I hope you all are doing great, first of all I would like to say thanks for successful completion of this year of Microbioz India and by the end of this year Microbioz team going to complete its three successful year. Dear friends once again we are going to introduce you all about role of our microbes in maintaining quality control of pharmaceutical and other R & D laboratory entitled by: “Boost your brain power with microbes “.The cover story explains how does healthier microbes helps in boosting our brain.

Apart from cover story magazine also rich research news information collected from worldwide sources the research may help our audience for stay updated with current research news information happening across the globe. Apart from research news information magazine focus in few aspects of biotech and Pharma business news updates. Find annual updates on scientists speak in favour of Microbioz India.

Dear friends Microbioz India magazine from since last one year dedicated to build huge academic audiences and as we know our team members ,authors always tried to win heart of each audience for expel out quality cover story and maintain magazine contents in each edition and we ensure you all for doing same in near future. Collect lot of open scholarship position for pursuing higher education in the field of Microbiology, Biotechnology and Medical Sciences from reputed Universities of across the globe.

In last phase of this magazine how we can forget to announce the names of winners of our November 2015 edition of crossword, Dear friends we request you to all for earlier submission of your answers and other feedbacks about magazine editions.

Chief Editor Mr.Jeetendra Kumaar

Page 5: December 2015 issue of Microbioz India

Dear friends,readers,supporters I hope you all are doing great, first of all I would like to say thanks for successful completion of this year of Microbioz India and by the end of this year Microbioz team going to complete its three successful year.

Bye year 2015 with few unforgettable memories among we all we lost few and achive success over few targets, Number of pathogenic disease out breaks expels out their original effects in all around year few…Read more..

Thanks to professors and eminent scientists of around the globe interviewed by Microbioz India in this year, we all welcome appreciating words for Microbioz Magazine.

Scientists from University of Georgia explains large quantity of microbes present in each litre of sea water represent a structural community of microbes which in turn helps in understanding of global climatic change, a review report published in journal Science by University of Georgia marine scientist Mary Ann Moran.

In last phase of this magazine how we can forget to announce the names of winners of our November 2015 edition of crossword, Dear friends we request you to all for earlier submission of your answers and other feedbacks about magazine editions.

Cover Story: Boost your Brain Power with Food Microbes

Top most infectious disease in news coverage : 2015

Scientist speak for Microbioz India : 2015

Study on ocean microbes : Research news information

Scholarship news updates Collect lot of open scholarship position for pursuing higher education in the field of Microbiology, Biotechnology and Medical Sciences from reputed Universities of across the globe.

December Crossword:Microbioz India

Exclusive Research news & Biotech, Pharma Business news information in our latest edition

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H.O: 631/63, Chinhat, Lucknow, U.P., India: 226012 www.microbiozindia.com [email protected]

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FFor healthy life we should

maintain our internal microbial ecology means we should maintain healthier microbes in our GI tract, these microbes some what makes friendly relationship inside our body so try to keep eating food rich with these microbes here we will try to explain few selected foods which can help in improving healthier gut microbiota which in turn boosts in coping up with stress. According to blog Prevention.com the more types of friendly gut bacteria we harbor, the better job of digestion the gut does, and the less chance that a particular food or food component will upset it or trigger a harmful inflammatory response.

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Healthier Microbes in foods

For healthy life we should maintain our internal microbial ecology means we should maintain healthier gut microbes in our GI tract, these microbes some what makes friendly relationship inside our body so try to keep eating food rich with these microbes here we will try to explain few selected foods which can helps in improving healthier gut microbiota which in turn boosts in coping up with stress. According to blog Prevention.com the more types of friendly gut bacteria we harbor, the better job of digestion the gut does, and the less chance that a particular food or food component will upset it or trigger a harmful inflammatory response.

Almonds

"Almond" is also the name of the edible and widely cultivated seed of this tree. Within the genus Prunus, it is classified with the peach in the subgenus Amygdalus, distinguished from the other subgenera by the corrugated shell (endocarp) surrounding the seed. The fruit of the almond is a drupe, consisting of an outer hull and a hard shell with the seed (which is not a true nut) inside. Shelling almonds refers to removing the shell to reveal the seed helps in maintain gut microlflora.

Asparagus

Also known as world’s healthiest green food, the fleshy green spears of asparagus are both succulent and tender and have been considered a delicacy since ancient times. This highly prized vegetable arrives with the coming of spring, when its shoots break through the soil and reach their 6-8 inch harvest length. In California the first crops are picked as early as February, however, their season generally is considered to run from April through May. You may have heard about two foods — chicory root and Jerusalem artichoke — that are widely recognized as providing health benefits for our digestive tract. These health benefits involve a special area of digestive support called "prebiotics" offered by a compound known as inulin. Which in turn boosts microbial flora in gut.

Bananas The banana is an edible fruit, botanically a berry, produced by several kinds of large herbaceous flowering plants in the

genus Musa. In some countries, bananas used for cooking may be called plantains. The fruit is variable in size, color and firmness, but is usually elongated and curved, with soft flesh rich in starch covered with a rind which may be green, yellow, red, purple, or brown when ripe.

Burdock root

Counteract calcium loss during urination and build strong bones by supplementing with a banana. Improve your mood and reduce PMS symptoms by eating a banana, which regulates blood sugar and produces stress-relieving relaxation. Musa species are native to tropical Indomalaya and Australia, and are likely to have been first domesticated in Papua New Guinea. They are grown in at least 107 countries, primarily for their fruit, and to a lesser extent to make fiber, banana wine and banana beer and as ornamental plants.

Cereal grains (whole wheat, barley, rye)

A cereal is any true grass cultivated for the edible components of its grain (botanically, a type of fruit called a caryopsis), composed of the endosperm, germ, and bran. Cereal grains are grown in greater quantities and provide more food energy worldwide than any other type of crop; they are therefore staple crops. Some plants often referred to as cereals, like buckwheat and quinoa, are considered instead pseudo cereals, since they are not grasses.

Cover Story…

Microbioz India, December 2015 www.microbiozindia.com Page No. 10

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Researchers are now beginning to understand the ways in which bacteria living in the human gut—the gut microbiota—communicate with and influence brain health. The concept of a faulty "gut/brain axis" has been associated with various neurologic and psychiatric outcomes and is thought to be explained, at least in part, by immune dysfunction and inflammation triggered by poor gut health.

Chicory root

Common chicory, Cichorium intybus, is a somewhat woody, perennial herbaceous plant of the dandelion family usually with bright blue flowers, rarely white or pink. Many varieties are cultivated for salad leaves, chicons (blanched buds), or for roots (var. sativum), which are baked, ground, and used as a coffee substitute and additive. It is also grown as a forage crop for livestock.[5] It lives as a wild plant on roadsides in its native Europe, and now common in North America, China, and Australia where it has become widely naturalized.

Endive

Endive is a leaf vegetable belonging to the genus Cichorium, which includes several similar bitter leafed vegetables. Species include endive (Cichorium endivia), Cichorium pumilum, and common chicory (Cichorium intybus). Common chicory includes chicory types such as radicchio, puntarelle, and Belgian endive.

Garlic

Allium sativum, commonly known as garlic, is a species in the onion genus, Allium. Its close relatives include the onion, shallot, leek, chive.and rakkyo.With a history of human use of over 7,000 years, garlic is native to central Asia,[4] and has long been a staple in the Mediterranean region, as well as a frequent seasoning in Asia, Africa, and Europe. It was known to Ancient Egyptians, and has been used for both culinary and medicinal purposes.

Fermented vegetables (kimchi, sauerkraut)

Fermentation is the process by which yeast or bacteria convert sugar to alcohol, and it occurs when bread leavens or beer and wine are made. While the buzz about kimchi, sauerkraut, and other foods exaggerates their perks, research has shown fermented foods can improve your health in at least a few ways.

Cultured dairy products (buttermilk, yogurt, kefir, cheese)

Cultured dairy foods enjoy a long and vibrant history. In every society that historically consumed dairy foods, cultured yogurt and other probiotic dairy foods earned a much-loved and much-respected place in the indigenous diets. That place was rightly deserved, too. While culturing milk and cream inevitably offered the practical benefit of enabling dairy foods to last longer; it also enhanced their nutrient profile.

Fermented grains and beans

Beans and legumes are notoriously wonderful as a cheap source of plant-based protein. They contain a variety of micronutrients as well, including B vitamins, iron, and calcium. Unfortunately, beans are also notorious for causing intestinal discomfort. If you’re ready to switch to a wholefoods, plant-based diet, congratulations!! I’m absolutely thrilled to guide you! Non-gluten grains, beans, nuts and seeds are a big part of the Yogitrition Plan–I want you to eat them regularly, and I want you to reap the full benefits.

Cover Story…

Microbioz India, December 2015 www.microbiozindia.com Page No. 11

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Gut Microbes in stress management

We all well known and its well excepted that gut microbiota plays an important role in coping with stress management, obesity, diabetes elated disorder and many other brain related things. According to report published in Business insider India, Mark Lyte is studied this relationship since last 30 years and When he first started this work, "it was dismissed as a curiosity," according to a recent profile of research into the gut-brain connection in The New York Times, but over time, as Lyte and others continued to publish their research, they uncovered more and more compelling evidence that bacteria could not only affect but could perhaps even be a causal factor in mental disorders - something that implies they could also be eventually used to treat these same conditions.

Stress changes the composition, diversity and number of intestinal bacteria, said the team at Ohio State University. The communities of bacteria become less varied, and there are greater numbers of potentially harmful bacteria. The study is published in the March 2011 issue of the journal Brain, Behavior, and Immunity.

According to Robert Preidt a report published in health day, "These changes can have profound implications for physiological function," lead researcher Michael Bailey said in a journal news release. "When we reduced the number of bacteria in the intestines using antibiotics, we found that some of the effects of stress on the immune system were prevented. This suggests that not only does stress change the bacteria levels in the gut, but that these alterations can, in turn, impact our immunity."

The four dominant phyla in the human gut are Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria. Most bacteria belong to the genera Bacteroides, Clostridium, Faecalibacterium, Eubacterium, Ruminococcus, Peptococcus, Peptostreptococcus, and Bifidobacterium.

Stomach Microbiota and brain relationship

It was occasion of 4th Gut Microbiota for Health World Summit 2015 and Researcher Elaine Hsiao from the California Institute of Technology (Caltech) during her interview for “Drug microbiota world watch” explains, how the gut microbiota influences our brain and how our brain, in turn, affects the gut microbiota. An essential dialogue for finding out how the so-called “second brain” can influence our behavior and how it relates to the rest of our nervous system. “The gut is often called the second brain because it has its very own nervous system”.

No doubt number stories and research article completely suggests and confirms our GI tract micro flora connected with number psychiatric behaviors which includes stress, emotions like mood and depressions.recnetly an article published in blog mind full by Jennifer Wolkin in month of August 2015,Most of us can relate to the experience of having butterflies in our stomach, or to a visceral gut-wrenching feeling, and how often are we told not to ignore our “gut-instinct” or “gut-feeling” when making a decision. Even from our simple slang, it’s clear just how symbolically connected the gut is to our emotions. Now, there’s tangible proof to support these popular metaphors. Research has shown that the body is actually composed of more bacteria than cells. We are more bug than human! Collectively, these trillions of bacteria are called the microbiome. Most of those bacteria reside in our gut, sometimes referred to as the gut microbiota, and they play multiple roles in our overall health.

Cover Story…

Microbioz India, December 2015 www.microbiozindia.com Page No. 12

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The gut is no longer seen as an entity with the sole purpose of helping with all aspects of digestion. It’s also being considered as a key player in regulating inflammation and immunity. A healthy gut consists of different iterations of bacteria for different people, and this diversity maintains wellness. A shift away from “normal” gut microbiota diversity is called dysbiosis, and dysbiosis may contribute to disease. In light of this, the microbiome has become the focus of much research attention as a new way of understanding autoimmune, gastrointestinal, and even brain disorders.

Researchers are now beginning to understand the ways in which bacteria living in the human gut—the gut microbiota—communicate with and influence brain health. The concept of a faulty "gut/brain axis" has been associated with various neurologic and psychiatric outcomes and is thought to be explained, at least in part, by immune dysfunction and inflammation triggered by poor gut health.

Serotonin a well known brain neurotransmitter and it is esteemed that 90 percent of the body serotonin produced in the digestive tract. In fact, altered levels of this peripheral serotonin have been linked to diseases such as irritable bowel syndrome, cardiovascular disease, and osteoporosis. New research at Caltech, published in the April 9 issue of the journal Cell, shows that certain bacteria in the gut are important for the production of peripheral serotonin. According to, Elaine Hsiao from California Institute of Technology (CALTEC), "More and more studies are showing that mice or other model organisms with changes in their gut microbes exhibit altered behaviors," "We are interested in how microbes communicate with the nervous system. To start, we explored the idea that normal gut microbes could influence levels of neurotransmitters in their hosts." Credit goes to California Institute of Technology,(CALTECH).

References

California Institute of Technology, Gut microbiota watch, medicine.net, www.medscape.com,www.mindful.org www.nytimes.com Montiel-Castro, A. J.; González-Cervantes, R. M.; Bravo-Ruiseco, G.; Pacheco-López, G. (2013). "The microbiota-gut-brain axis: Neurobehavioral correlates, health and sociality". Frontiers in Integrative Neuroscience 7. doi:10.3389/fnint.2013.00070.Jump up ^ Foster, J. A.; McVey Neufeld, K. A. (2013). "Gut–brain axis: How the microbiome influences anxiety and depression". Trends in Neurosciences 36 (5): 305–312. doi:10.1016/j.tins.2013.01.005. PMID 23384445.Jump up ^ Cryan, J. F.; Dinan, T. G. (2012). "Mind-altering microorganisms: The impact of the gut microbiota on brain and behavior". Nature Reviews Neuroscience 13 (10): 701–712. Doi: 10.1038/nrn3346. PMID 22968153.www.yogitrition.com www.nourishedkitchen.com www.shape.com

Cover Story…

Microbioz India, December 2015 www.microbiozindia.com Page No. 13

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Featured Article…

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Featured Article…

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Flu

Flu is also one of highly contagious viral infections caused by series of flu virus, On Thursday, October 15th, the Food and Agriculture Organization (FAO) of the United Nations released a warning announcing the start of a fourth wave of avian influenza H7N9. The H7N9 strain particularly threatens the poultry industry and those working directly with animals. Since its initial emergence in China in 2013, the country has seen a steady rise of human infections of H7N9.In start of year disease place a role in media as a disease history, because there is no commercially available vaccine in existence, prevention of H7N9 is key to protection from infection. Prevention of H7N9 includes practicing proper hand hygiene, respiratory hygiene, and food safety. According to the World Health Organization (WHO), influenza viruses become inactivated by “normal temperatures for cooking meat products”.

Cholera

Recently the ministry of health of the Democratic Republic of the Congo (DRC), has informed WHO about a wide outbreak of Cholera in the country, since the beginning of the year, 19,705 cases have been reported in DRC. As of 29 November, the following provinces had reported cases: South Kivu (4,906), ex-Katanga (4,565), Maniema (3,971), North Kivu (3,294) and ex-Oriental (2,969). A high number of cases are still reported in the province of South Kivu where the situation is particularly worrying because of the presence of camps hosting refugees from Burundi. Courtesy: Outbreak news today. According to report by above news source, Water sanitation and hygiene activities, such as water chlorination, are being implemented. Communication and health education activities are also continuing.

The MoH and WHO conducted joint risk assessment missions in South Kivu, Maniema and Kisangani. Following their recommendations, an updated control and response plan was developed. WHO also provided technical support and coordination for the implementation of prevention and control measures. The implementation of oral cholera vaccine campaigns is being discussed with national authorities.

References

BBC news, Outbreak news today, www.healthmap.org http://www.fao.org/ag/againfo/programmes/en/empres/news_151015.html#sthash.qkl9Gflp.dpuf

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Featured Article…

Microbioz India, December 2015 www.microbiozindia.com Page No. 18

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SScientists from University of Georgia explains large quantity of microbes present in each litre of sea water represent a structural

community of microbes which in turn helps in understanding of global climatic change, a review report published in journal Science by University of Georgia marine scientist Mary Ann Moran. The ocean microbes are organism studied first and almost cover maximum part of earth surface. According to researcher, "Marine microbes make up a vast biological network," said Moran, a Distinguished Research Professor in the UGA Franklin College of Arts and Sciences. "Microbes are responsible for virtually all the photosynthesis that occurs in the ocean, as well as the cycling of carbon, nitrogen, phosphorus and other nutrients and trace elements. They literally run the oceans."

"Improved understanding of the function of microbiomes is crucial, not only in the ocean but in systems as varied as the human body, agricultural soils and groundwater," Moran said. "The next decade will bring a period of rapid learning about how microbes communicate, redistribute materials and regulate activities that have implications for environmental integrity and human health."

Note: The above story is for information purpose for more information goes through original story source.

Story Source:

University of Georgia

Journal References

Mary Ann Moran. The global ocean microbiome. Science, December 2015 doi: 10.1126/science.aac8455

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Study on ocean microbes may help for better understanding of climatic change

News Infocus….

Microbioz India, December 2015 www.microbiozindia.com Page No. 20

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AAccording to study published in BMJ reaction triggered in egg allergy and asthmic child through Flu vaccine recent study shows, the vaccine is

also appropriate for young people with well-controlled asthma or recurrent wheeze.

LAIV is a nasal spray vaccine developed specifically for young people, but there are limited safety data for its use in young people with egg allergy and/or asthma. Some guidelines recommend against using LAIV in children under 5 years with a history of recurrent wheeze or asthma.

According to study,

A total of 779 young people (aged 2-18 years) with egg allergy were recruited from 30 UK allergy centres and immunized with LAIV. Some 315 (40%) had experienced an allergic reaction to egg in the past 12 months, 270 (35%) had experienced previous anaphylaxis to egg, and 445 (57%) had doctor diagnosed asthma or recurrent wheeze. Participants were observed for at least 30 minutes after vaccination and followed-up by telephone 72 hours later. Those with a history of recurrent wheeze or asthma underwent further follow-up four weeks later.

It also provides evidence to support the revised Department of Health guidance for the 2015/16 season that, with the exception of children "with severe anaphylaxis to egg which has previously required intensive care, children with an egg allergy can be safely vaccinated with Fluenz Tetra® in any setting (including primary care and schools)."

1. Note: The above story is for information purpose for more information goes through original story source.

Story Source: BMJ

Journal References

Paul J Turner, Jo Southern, Nick J Andrews, Elizabeth Miller, Michel Erlewyn-Lajeunesse. Safety of live attenuated influenza vaccine in young people with egg allergy: multicentre prospective cohort study. BMJ, 2015; h6291 DOI: 10.1136/bmj.h6291

Reaction triggered in egg allergy and asthmic child through Flu vaccine: Study shows

News Infocus….

Microbioz India, December 2015 www.microbiozindia.com Page No. 21

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Bacterial cells having BT-genes may help in treatment of roundworm infections

IIn recent research study scientist find intestinal nematodes and round worms infects billions of people around the globe, Now researcher find

success over treatment of these infections through insertion of naturally occuring BT-genes in harmless bacterium and insertion in humans through Probiotics dairy products. The research is published in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.

According to research study,

Normally, molecules of substantial size can only escape from a cell either if cellular machinery in the cell membrane actively exports them, or if the microbe breaks open in a process called lysis. "We observed that large proteins could be released from this particular bacterium without cell lysis or an active export system," said Todd Klaenhammer, PhD, Distinguished University Professor in the Department of Food, Bioprocessing and Nutrition Sciences, at North Carolina State University, Raleigh. He said the mechanism for this "leaky Lactococcus phenomenon" is not completely understood. Importantly, the leaky behavior did not interfere with normal bacterial cell growth or viability, he said.

"What if someday children who are infected with parasitic round worms could simply eat a dish of locally made fermented milk or yogurt and be cured," said lead author Evelyn Durmaz, MS, a research associate at North Carolina State University. Klaenhammer also noted that "Our laboratories are currently investigating the possibilities of using probiotic bacteria and food safe bacteria to orally deliver vaccines and other biotherapeutics directly to the GI tract."

Note: The above story is for information purpose for more information goes through original story source.

Story source: American Society for Microbiology

Journal References

Evelyn Durmaz, Yan Hu, Raffi V. Aroian, Todd R. Klaenhammer. Intracellular and extracellular expression of Bacillus thuringiensis crystal protein Cry5B in Lactococcus lactis for use as an anthelminthic. Applied and Environmental Microbiology, 2015; AEM.02365-15 DOI: 10.1128/AEM.02365-15

News Infocus….

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West Nile and Dengue virus infections treated: Peroxisomes may help

RResearcher from University of Alberta, faculty of medicine and dentistry recently opens a new secret over treatment of West Nile and Dengue

virus treatment, in new discovery scientists examines a previously unknown connection between flaviviruses--a classification of viruses that include West Nile virus, Dengue virus and tick-borne encephalitis virus--and organelles (a specialized subunit within a cell) known as Peroxisomes that help coordinate the body's immune responses. Postdoctoral fellow Jaehwan You and PhD student Shangmei Hou, the lead authors on the study, found

That flaviviruses induce degradation of a protein called Pex19, which is essential for the building of new Peroxisomes, setting off a chain reaction that could leave the body more vulnerable to viral infection. The research published in December edition of the Journal of Virology.

According to research,

"Peroxisomes, as it turns out, are required for production of an antiviral molecule called interferon lambda," says Tom Hobman, senior author and professor of cell biology at the U of A. "Interferon lambda is produced by infected cells and has been shown to inhibit replication of multiple viruses. We hypothesized that loss of Peroxisomes results in the loss of the ability of the cells to produce this interferon, which indeed was found to be the case.

"It looks like the virus may be targeting Peroxisomes to prevent antiviral defense by the cell."

Note: The above story is for information purpose for more information goes through original story source.

Story source: University of Alberta Faculty of Medicine & Dentistry

Journal References

Jaehwan You, Shangmei Hou, Natasha Malik-Soni, Zaikun Xu, Anil Kumar, Richard A. Rachubinski, Lori Frappier, Tom C. Hobman. Flavivirus infection impairs Peroxisomes biogenesis and early anti-viral signaling. Journal of Virology, 2015; JVI.01365-15 DOI: 10.1128/JVI.01365-15

News Infocus….

Microbioz India, December 2015 www.microbiozindia.com Page No. 23

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Millions of bacterial presence in water pipes

RResearcher from University of Lund, Swedish published a research describing existence of millions of bacteria in water pipes. The discovery of

researchers in Applied Microbiology and Water Resources Engineering show that the diversity of species of bacteria in water pipes is huge and those bacteria may play a larger role than previously thought. Among other things, the researchers suspect that a large part of water purification takes place in the pipes and not only in water purification plants.

The concern research published in Microbes and Environments. Catherine, Professors Peter Rådström and Kenneth Persson, and colleagues Björn Canbäck and Tomas Johansson and doctoral student, Katharina Lührig.

According to researchers,

"A previously completely unknown ecosystem has revealed itself to us. Formerly, you could hardly see any bacteria at all and now, thanks to

techniques such as massive DNA sequencing and flow cytometry, we suddenly see eighty thousand bacteria per millilitre in drinking water," says

researcher Catherine Paul enthusiastically.

"From having been in the dark with a flashlight, we are now in a brightly lit room, but it is only one room. How many different rooms are in the

house is also an interesting question!" she continues.

"We suspect there are 'good' bacteria that help purify the water and keep it safe -- similar to what happens in our bodies. Our intestines are full

of bacteria, and most the time when we are healthy, they help us digest our food and fight illness, says Catherine Paul.

Note: The above story is for information purpose for more information goes through original story source.

Story source: University of Lund, Sweden

Journal References

Katharina Lührig, Björn Canbäck, Catherine J. Paul, Tomas Johansson, Kenneth M. Persson, Peter Rådström. Bacterial Community Analysis of

Drinking Water Biofilms in Southern Sweden. Microbes and environments, 2015; 30 (1): 99 DOI: 10.1264/jsme2.ME14123

News Infocus….

Microbioz India, December 2015 www.microbiozindia.com Page No. 24

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Flu vaccine is less effective in elderly

AA research work published in Cell press: Immunity, describing Flu vaccine effectiveness, Scientists describing around November-December in

each year Flu virus effects huge number of peoples around the world, the findings also reveal novel molecular signatures that could be used to predict which individuals are most likely to respond positively to vaccination.

According to researcher,

"We provide novel evidence of a potential connection between the baseline state of the immune system in the elderly and reduced responsiveness to vaccination," say co-senior study authors Shankar Subramaniam of the University of California, San Diego, and Bali Pulendran of Emory University. "By providing a more complete picture of how the immune system responds to vaccination, our findings may help guide the development of next-generation vaccines that offer long-lasting immunity and better protection of at-risk populations."

Note: The above story is for information purpose for more information goes through original story source.

Story source: Cell press

Journal References

Nakaya and Hagan et al. Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures. Immunity, 2015 DOI: 10.1016/j.immuni.2015.11.012

News Infocus….

Microbioz India, December 2015 www.microbiozindia.com Page No. 25

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Famous Indian Homoeopathy brand Dr.Batra’s awarded by best “Healthcare Clinic award” in Europe

Dr.Batra’s one of most famous Indian Homoeopathy brand awarded by best “Health care Clinic award” in Europe at ceremony in Oxford.

The brand recently opens its new base in Wembley area of the city and was honored by Oxford University and British Business Society, Award is received by brand chairman and founder, Dr.Mukesh Batra in town hall ceremony at Oxford in this week.

Accordind to Dr.Mukesh,

"It is an honour to be recognized amongst clinics in 40 countries as the Best Healthcare Clinic. At our clinics we have always endeavoured to provide the best of doctors and medical services to our patients. This is a matter of pride and prestige not only for our clinics but the service and dedication of our doctors as well, on same occasion Dr.Mukesh also announce the name of CEO of the year.

Story Credit: Economic Times

Dr.Mukesh Batra, Brand chairman and founder

Biotech Business…

Microbioz India, December 2015 www.microbiozindia.com Page No. 26

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Amgen wins quick approval for its cancer fighter drug “Imlygic”

AAmgen a California based pharmaceutical company wins quick approval for its cancer fighter drug in Europe just after two

months of its FDA approval.

The Thousand Oaks, CA-based company said today that the European Commission had approved Imlygic to treat inoperable melanoma that has spread, except for those patients whose cancer has spread to the brain, bone, lungs and gut.

The injection uses a genetically modified strain of the herpes virus, the so-called cold sore virus, to invade tumors and replicate itself, killing cancer and spurring an immune response to multiply its effect. Injecting Imlygic into melanoma lesions shrank tumors at a statistically significant rate in its Phase III trial.

Original Story source: http://www.fiercepharma.com/

Biotech Business…

Microbioz India, December 2015 www.microbiozindia.com Page No. 27

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Fully Funded PhD Position for International Students at IST Austria, 2016-2017

About Scholarship Institute of Science and Technology Austria (IST Austria) is inviting applications for fully funded PhD position starting in September 2016. This

position is open to applicants from all over the world to pursue a career in science. The PhD program is typically 4 to 5 years in length, depending on whether the student has been admitted with a bachelor’s or master’s degree, as well as on the student’s individual progress. The submission deadline is January 8, 2016.

Eligibility Highly qualified students from all disciplines of the natural sciences, mathematics, computer sciences, and any related interdisciplinary areas, who

are committed to pursuing their scientific career in an international research environment, are invited to apply. All applicants must hold a master’s or bachelor’s degree (or equivalent), or anticipate the completion of the degree before September 2016.

Participating students are expected to be proficient in written and oral English.

How to Apply Apply for PhD program by submitting your application using online application form. To complete your application, you will need the following:

Your resume/CV: include your educational history since high school, relevant work experience, additional qualifications, list of publications (if any) and scholarships, awards, etc. (if any)

Statement of purpose: a 1-2 page essay in which you explain Why you want to enter our PhD program, the research area(s) you find the most interesting and Which professor(s) you may be interested in studying with

Three referees who taught or supervised your work in academic setting: you will need to enter their names, institutions, and email addresses.

Deadline

The submission deadline is January 8, 2016.

For Details: http://ist.ac.at/graduate-school

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Ecosystem controls of competition for nitrogen between plant roots and soil microbes: PhD project

About Project Understanding the nitrogen cycle is crucial to understanding ecosystems and how they respond to change. Most nitrogen enters soil as protein.

This is cleaved to amino acids and short peptides before it can be taken up by microbes and plant roots. It is known that there is fierce competition between microbes and plants for these forms of nitrogen at the root surface and that the outcome of competition varies between plant species, soils and ecosystems.

Eligibility Full studentships are available to UK and EU candidates who have been ordinarily resident in the UK throughout the 3-year period immediately

preceding the date of an award. EU candidates who have not been resident in the UK for the last 3 years are eligible for "tuition fees-only" awards.

How to Apply

Apply online

Deadline

Sunday, January 24, 2016

For Details Bangur University

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Discovery of novel pharmaceuticals from marine and desert microorganisms: PhD project

About Project Microorganisms from extreme environments such as the deep sea and hyper arid deserts have been shown to produce a range of complex

natural products with high biological activity. In this project you will investigate the chemistry of these compounds and their potential for treating a range of diseases. Via collaborations we obtain desert and marine samples from which you will isolate unique bacterial and fungal strains. Cultivating these under different conditions gives rise to varied metabolic profiles.

Eligibility Applicants must hold, or expect to receive, a first or upper second class honours degree (or equivalent) in Chemistry, biochemistry or pharmacy

with knowledge of Organic chemistry, Nuclear magnetic resonance spectroscopy and mass spectrometry.

How to Apply

Formal applications can be completed online: http://www.abdn.ac.uk/postgraduate/apply. You should apply for PhD in Chemistry, to ensure that your application is passed to the correct College for processing. Please ensure that you quote the project title and supervisor on the application form. Informal inquiries can be made to Professor M Jaspars, ([email protected]) with a copy of your curriculum vitae and cover letter. All general enquiries should be directed to the Graduate School Admissions Unit ([email protected]).

Deadline

Applications are accepted in all around the year.

For Details

Aberdeen University

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Bacteriophages as agents of rumen microbiome regulation of feed efficiency and methane emissions: PhD Project

About Project The work to be carried out in this proposed studentship involves investigating the effect of phages on rumen function, with

particular emphasis on identifying those which result in a reduction in methane emissions, an increase in digestibility of the feed and a beneficial change in the colonisation strategy of the rumen microbes on fresh forage. The goal is to identify phages that can be utilised as part of a feed additive strategy to create rumen conditions more conductive to increased productivity and lower methane emissions in ruminant production systems.

Eligibility

Applicants must hold, or expect to receive, a first or upper second class honours degree (or equivalent) in Chemistry, biochemistry or pharmacy with knowledge of Organic chemistry, Nuclear magnetic resonance spectroscopy and mass spectrometry.

How to Apply

To apply, please submit the following to the Postgraduate Admissions Office (email [email protected] or address below) by 8th January 2016:

A completed Postgraduate Application Form, plus two references submitted by the deadline. Application and reference forms may be downloaded from http://www.aber.ac.uk/en/postgrad/howtoapply/apply-offline/.

A completed KESS participant application form (put the reference number AU10013 in the top right hand box) and an up-to-date CV. KESS application forms are available to download at the link below. http://www.aber.ac.uk/en/rbi/staff-students/knowledge-economy-skills-scholarships/

A PhD proposal of up to 1,000 words where you expand on your experience and interests and describe why you are a good candidate for this research studentship. Please refer to the Project Description.

Deadline: Friday, January 22, 2016

For Details: Aberystwyth University

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Improving productivity in extensively managed grazing ruminants: PhD Project

About Project The UK uplands carry around 12 million breeding ewes and more than a million suckler cattle (representing over 60% of the UK

total). The nutritional quality of grazed herbage varies throughout the grazing season however, the feeding of supplementary concentrates to grazing livestock is not a practical option as it is time-consuming and expensive. Low moisture feed blocks are a commercially available product that allows all animals, extensive or intensive, to be supplemented with readily available energy and minerals.

Eligibility

Applicants should hold, or expect to obtain, a minimum of a first or good upper-second class honours degree (or equivalent) in a relevant subject Applicants with expertise in animal science, rumen microbiology are particularly welcome.

How to Apply

Contact the lead supervisor Prof Jamie Newbold ([email protected]) to discuss the project, or for general queries Michelle Allen ([email protected]). For information on IBERS see View Website and for how to apply see View Website - please enter the lead supervisor name under “Project title applied for”.

Deadline

Sunday, January 31, 2016

For Details

Aberystwyth University

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Do extreme weather events promote greenhouse gas production and emission from agricultural soils? (GHG-Extreme): PhD Project

About Project The UK is experiencing increasing frequencies of extreme weather events, which are a major threat to agriculture. Extreme

weather impacts on soil processes and function through interacting effects on soil biological, chemical and physical factors that control both production and emissions of the greenhouse gases (GHG) nitrous oxide, methane and carbon dioxide. You will explore relationships (and ‘tipping points’) between soil conditions, soil processes and fluxes of these gases in laboratory- and plot-scale experiments following simulated flooding and drought.

Eligibility

Applicants should hold a minimum of a UK Honours Degree at 2:1 level (or equivalent Masters) in environmental, biological, microbiological, physical sciences. A strong grasp of mathematics and experience of laboratory and field practical work would be advantageous.

How to Apply

Apply through online go through website for details, Full studentships are available to UK and EU candidates who have been ordinarily resident in the UK throughout the 3-year period immediately preceding the date of an award. EU candidates who have not been resident in the UK for the last 3 years are eligible for "tuition fees-only" awards (no maintenance grant).

Deadline: Sunday, January 24, 2016

For Details: Bangor University

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Advancement & Optimization of Ancient DNA Protocols: PhD Project

About Project The Archaeogenetics department at the Max Planck Institute for the Science of Human History in Jena, Germany, is offering a PhD

position on innovative method development for ancient DNA research beginning in summer 2016. The overarching research topic at the institute is the use of novel scientific approaches from high throughput sequencing of ancient DNA from human populations and their pathogens to explore research questions related to human history & demography, gene-culture coevolution, and adaptation to infectious disease. The main foci are the relationship between humans and pathogens through time, human population dynamics on a (pre)-historical time-scale, and in tandem with microbial evolution.

Eligibility

The Max Planck Society is committed to employing more handicapped individuals and especially encourages them to apply. The Max Planck Institute is not a faculty, but is affiliated to, among others, the Eberhard-Karls University in Tübingen and the Friedrich Schiller University in Jena, Germany. Doctoral degrees will be granted by one of the affiliated universities.

How to Apply

Please apply online at https://s-lotus.gwdg.de/mpg/mjws/ag_phd_2016.nsf/registration

Deadline

Wednesday, February 10, 2016

For Details

Max Planck Institute for the Science of Human History

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Molecular Palaeopathology and Ancient Pathogen Genomics: the relationship between humans and pathogens through time: PhD Project

About Project The Archaeogenetics department at the Max Planck Institute for the Science of Human History in Jena, Germany, is offering a PhD position in

Ancient Pathogen Genomics beginning in summer 2016. The overarching research topic at the institute is the use of novel scientific approaches from high throughput sequencing of ancient DNA from human populations and their pathogens to explore research questions related to human history & demography, gene-culture coevolution, and adaptation to infectious disease. The main foci are the relationship between humans and pathogens through time, human population dynamics on a (pre)-historical time-scale, and in tandem with microbial evolution.

Eligibility

The Max Planck Society is committed to employing more handicapped individuals and especially encourages them to apply. The Max Planck Institute is not a faculty, but is affiliated to, among others, the Eberhard-Karls University in Tübingen and the Friedrich Schiller University in Jena, Germany. Doctoral degrees will be granted by one of the affiliated universities.

How to Apply Please apply online at https://s-lotus.gwdg.de/mpg/mjws/ag_phd_2016.nsf/registration

Deadline: Wednesday, February 10, 2016

For Details: Max Planck Institute for the Science of Human History

Note: The credit of these scholarships goes to scholarshippoitions.com and findphd.com

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