date prepared october 10, 2014 - northeastern universitydate prepared october 10, 2014 name gregory...

Date Prepared October 10, 2014

Name Gregory M. Miller Ph.D.

Office Address Northeastern University

Bouve College of Health Sciences

Department of Pharmaceutical Sciences and Center for Drug Discovery

Mugar 312D

360 Huntington Ave.

Boston, MA 02115

Home Address 21 Curtiss Circle, Sudbury, MA 01772

Work Phone (617)-373-6985

Cell Phone (508) 930-8027

Work Email [email protected]

Work FAX (617)-373-6985

Place of Birth Bronx, New York

Education

1986 B.A. Psychology Ithaca College, NY

1991 M.A. Psychology-

Neuropsychology

Queens College, City University of

New York

1993 Ph.D. Biomedical Sciences Mount Sinai School of Medicine, City

University of New York

Postdoctoral Training

09/93-01/94 Research Fellow

in Medicine, Division

of Endocrinology and

Metabolism

Neuroendocrinology

and Neurobiology of

Reproduction

Mount Sinai School

of Medicine,

New York, NY

01/94-01/97

Research Fellow in

Medicine,

Neuroendocrine Unit

Neuroendocrinology

and Pituitary Tumor

Biology

Massachusetts

General Hospital and

HMS, Boston, MA

01/10 Responsible Conduct of Research (RCR) HMS, Boston, MA

03/13 PRIM&R, Public Responsibility in Medicine Baltimore, MD

and Research; IACUC 101 Training and

IACUC Research Animal Oversight

2

Faculty Academic Appointments

01/97-05/97 Instructor Medicine Harvard Medical School

05/97-12/04 Instructor Psychiatry Harvard Medical School

01/05 – 07/12

07/12 – 08/14

Assistant Professor

Associate Professor

Psychiatry

Psychiatry

Harvard Medical School


09/14 – 06/15 Visiting Associate

Professor

Psychiatry Harvard Medical School

08/14 – 06/15 Associate Professor Department of

Pharmaceutical

Sciences and Center

for Drug Discovery

Northeastern

University

Appointments at Hospitals/Affiliated Institution

1/95 – 5/97 Assistant in

Biochemistry

Neuroendocrine Unit,

Medicine

Massachusetts General Hospital,

Boston, Massachusetts

9/14 – 6/15 Visiting Scientist Dept. of Psychiatry Beth Israel Deaconess Medical

Center

Major Administrative Leadership Positions

1997-2005 Division Manager

Division of Neurochemistry

New England Primate Research

Center, Harvard Medical School

2006-2008

Acting Chair, Division of Neurochemistry



2006-2014

Director, Primate Genetics Core



2007-2011 Director of Research and Compliance

Mouse Behavioral Laboratory



2012-2014 Director, Summer Undergraduate and

Summer Veterinary Internship Programs



3

Professional Service – Academic

2009 Member, Renovation Committee New England Primate Research


2010/2011 Chair, Search Committee for new Faculty in

Genetics



2012 Member, Animal Records Information

Technology Team



2013 Appointed Member

NEPRC IACUC (dissolved)



Professional Service, National and International

2007 - present Genomic Banking

Consortium

National Center for Research Resources

(now Office of the Director, NIH)

2007 - present Genetics Consortium National Center for Research Resources

(now Office of the Director, NIH)

2008-2009 Member

Publications Committee

College on Problem of Drug Addiction

2009-2012

Chair



2012-2016 Board Member

Board of Directors


2012-2014

Nominations Committee College on Problem of Drug Addiction

2014- Senior Oversight



Membership in Professional Societies

1992-present Society for Neuroscience Member

2001-present College on Problems of Drug Dependence

2001-2008 Associate Member

2008-present Member

2005-present Research Society on Alcoholism Member

2006-present International Society of Psychiatric Genetics Member

4

2007-present American Society for Pharmacology and

Experimental Therapeutics

Member

2013-present

Public Responsibility in Medicine and Research

(PRIM&R)

Member

Grant/Center Review Activities

2007 Grant Reviewer

October, 2007

Neurological Foundation of New

Zealand

2007 The Mount Sinai Center for Personalized

Medicine Review Panel

Andrea and Charles Bronfman

Philanthropies, New York, NY

October, 2007 Center Reviewer

June, 2008 Center Reviewer

2008 Grant Reviewer

February, 2008

National Science Foundation, The

Hague, the Netherlands

2008 Grant Reviewer Netherlands Genomic Initiative

May, 2008 Ad hoc Reviewer

2008-2010

Grant Reviewer

NSF

September, 2008 Ad hoc Reviewer

October, 2009 Ad hoc Reviewer

September, 2010 Ad hoc Reviewer

2009 B/START study Section NIDA/ NIH

March, 2009 Ad hoc Reviewer

2010 ZDA1 GXM-A (09) 1

March, 2010

NIDA/ NIH

Ad hoc Reviewer

2011 INIA WEST NIAAA/NIH

May, 2011 Reviewer

2011 INIA STRESS NIAAA/NIH

June, 2011 Reviewer

2011 ZAA1 GG (21) Ad hoc Reviewer

July, 2011 NIAAA/NIH

2012 Grant Reviewer Health Research Council of

February, 2012 New Zealand

5

2012 Harvard Catalyst Harvard Medical School

April, 2012 Reviewer

2013 ZRG1 NMB-A (02) S CSR

NIH Study Section

May/June, 2013

Grant Reviewer

2013 Grant Reviewer The Leverhulme Trust

Visiting Professorship Grant London, UK

2014 ZRG1 MDCN-B(05) CSR

NIH Study Section

November 2014

Grant Reviewer

Editorial Activities (2007-)

2007, 2010, 2011 BMC Genomics

2007 American Journal of Primatology

2007, 2008, 2010 Molecular Psychiatry

2007 PNAS

2008 Archives of General Psychiatry

2008, 2009 Bioorganic and Medicinal Chemistry

2008 Journal of Molecular Biology

2008 Pharmacological Review

2008 BMC Neuroscience

2009 Journal of Lipid Research

2009 Molecular Pharmacology

2009 Biochemical Pharmacology

2010 Neuropharmacology

2010 Psychoneuroendocrinology

2010 Journal of Neural Transmission

2010 Human Genetics

2011 Schizophrenia Research

2011 Neuroscience & Biobehavioral Reviews

2011 Journal of Neuroimmune Pharmacology

2011 Psychopharmacology

2012 Neuropsychopharmacology

2012 Chemical Biology & Drug Design

2012 Progress in Neuro-Psychopharmacology & Biological Psychiatry

2012 Genes, Brain and Behavior

2012 Journal of Neurochemistry

2012 Journal of Medical Primatology

6

2012 Synapse

2013 Translational Developmental Psychiatry

2013 Pharmacogenetics and Genomics

2014 Journal of Pharmacology and Experimental Therapeutics

2014 International Journal of Neuropsychopharmacology

2014 Physiology and Behavior

2. Other Editorial Roles

2009 Issue Editor, Genetic Tools for Understanding

the Primate Genome

Methods

2009-2012 Editor, News and Views Section Drug and Alcohol Dependence

Report of Funded and Unfunded Projects

Funding Information

Past

1991-1994 Endocrinology Training Grant

NIDDK/ T32DK07645

Graduate Trainee

Terry Davies, MD (PI)

1994-1995 Endocrine Training Grant

NIDDK/ P32DK07028

Postdoctoral Trainee

Anne Klibanski, MD (PI)

1996-1997 Somatostatin Receptors in Pituitary Tumors

NIDDK/ NRSA F32DK09281

PI (salary)

1997-2006 Evaluation of novel cocaine medications

NIDA/R01 11558

Co-I; PI Bertha K. Madras

1998-2008 Molecular probes for cocaine recognition sites

NIDA/ R01 06303 (Merit Award to Bertha K. Madras)

Co-I (1998-2006); PI Bertha K. Madras

Managing PI

(2006-2008; $731,859)

To explore neurochemistry of psychostimulant drugs of abuse and

therapeutics that target the brain monoamine transporters.

7

2004-2014 P51OD011103 (NEPRC Base grant)

NIH/OD/ORIP

Core Scientist; Jeffrey Flier PI

New England Primate Research Center Base Grant

Institutional support

2004-2010 Trace amine receptors in nonhuman primates

NIDA/ R01 016606

PI ($1,160,534)

To explore a newly-identified receptor family in primate brain.

2005-2007 NEPRC New Lab Start-up Package/ Promotion to Assistant Professor

New England Primate Research Center


PI (two years of salary plus $50,000/year for two years)

To establish an independent laboratory at NEPRC.

2006-2009 A monkey model of human mu-opioid receptor physiogenetics

NIDA/ R21 021180

PI ($457,399)

To explore comparable functionality of rhesus and human opioid receptor

polymorphisms.

2007-2009 Naturalistic modeling of alcoholism genotype/ phenotype relationships

and naltrexone pharmacogenomics in rhesus monkeys

NEPRC Pilot Project (competitive)

PI ($80,000 Direct Cost)

To establish a pharmacogenomic preclinical platform using rhesus

monkeys for medications development for alcoholism.

2007-2010 Alcohol abuse pharmacogenomics:building naturalistic rhesus monkey

models

NIAAA/ R21 016194

PI ($443,823)

To assess novel polymorphisms and explore genotype/phenotype

relationships in rhesus monkeys related to human alcoholism.

2007-2010 Methamphetamine effects via Trace Amine Associated Receptor 1

NIDA/ R21 022323

PI ($472,788)

To assess Trace Amine Associated Receptor 1 functionality with regard to

mechanisms of methamphetamine action in brain.

8

2008-2011 Neurogenetics of serotonin regulation: building naturalistic rhesus monkey

models

NIMH/ R21 077995

PI ($429,413)

To assess neurogenetic effects of polymorphisms in serotonergic genes.

2009-2011 TAAR1 polymorphisms in rhesus monkeys

NIDA/ R03 025802

PI ($173,500)

To identify and characterize Trace Amine Associated Receptor 1 genetic

variants in rhesus monkeys and humans.

2009-2010 Alcohol abuse pharmacogenomics: building naturalistic rhesus monkey

models

NIAAA/ R21 Supplement 016194-02S1

PI ($111,749)

To continue the productive research assessing novel polymorphisms and

exploring genotype/phenotype relationships in rhesus monkeys related to

human alcoholism.

2009 Methamphetamine Effects via Trace Amine Associated Receptor 1

NIDA/ R21 Supplement 022323-02S1

PI ($11,267)

To fund a summer student, Kate Sullivan, to work on a project using

Trace Amine Associated Receptor 1 Knockout Mice.

2009-2011 Development of a cognitive biomarker for alcoholism


Originator, Co-I; Donna Platt PI ($100,000 Direct Cost)

To search for biomarkers related to cognitive function in genetically-

identified alcohol-drinking rhesus monkeys prior to and after long-term

alcohol exposure.

2010-2011 A marmoset model of methamphetamine-induced cognitive, motor and

neurological effects


PI ($40,000 Direct Cost)

To investigate behavioral effects of methamphetamine mediated by Trace

Amine Associated Receptor 1.

2009-2014 Drug Abuse-related Neurobiology and Genetic Variance Modeled in

Rhesus Monkeys

NIDA/ K02 025697

PI ($615,275)

Independent Scientist Award (for salary support/career development)

https://commons.era.nih.gov/commons/genericStatus.do?actionRole=nonPI&applID=7941634&uhf-token=rlwIpAPFi%2Bq6rmgWq0tXKx9Uqno%3D

9

2009-2014 Opioid Receptor Polymorphisms and Nonhuman Primate Models of

Alcohol Abuse

NIAAA/ R01 016828

Co-I; Donna Platt PI ($2.060,315)

To assess a novel polymorphism and explore naltrexone

pharmacogenomics in rhesus monkeys related to human alcoholism.

*This grant succeeds R21 021180 (GMM-PI)

Current

2010-2015 Epigenetic Regulation of Serotonin: Relevance to HIV and

Methamphetamine Abuse

NIDA/ R21 030177 (3 yr RFP)

PI ($947,744 )

To investigate epigenetic mechanisms of serotonergic genes in normal and

SIV-infected rhesus monkeys.

(Currently Subcontracted to Northeastern University, Miller-PI)

2012-2014

Naltrexone and AIDS progression

1R21DA034420

PI ($437,500.00)

To investigate Low Dose Naltrexone as a novel therapeutic intervention for

HIV using previously SIV-infected rhesus macaques.

(Currently Subcontracted to Northeastern University, Miller-PI)

2010-2015 Functional genetic evolution of human brain behavior

5R01AA19688

Co-I; Eric Vallender PI ($1,956,412)

To investigate functional polymorphisms in rhesus monkeys

(Currently suspended due to PI relocation)

2013- Unrestricted Faculty Research Funds

PI (~$180,000)

These funds are transferable to a new institution or can be used for any

academic-related endeavor.

(Currently in transfer to Northeastern University

Current Unfunded Projects

2014 2R01DA011558-10A1 (MPI)

Novel psychostimulant drugs of abuse: behavior, biology, pathology.

Miller PI; Madras PI

Impact Score: 44, Percentile Score: 46.0

10

2014 1R21DA036708-01

Immunological actions of methamphetamine via trace amine associated receptor 1

Miller-PI

Impact Score: 58

2014 1R01AA021189-01A1

Trace amine associated receptor 1 in alcohol behaviors and treatments

Miller-PI

Impact Score: 49

2014 TAAR1-Cannabinoid Receptor Signaling Interactions in Drug Abuse

R21 submission 10/16/14

Report of Local Teaching and Training

Teaching of Students in Courses

1998 Substance Abuse: Addictive Process

ABS PS 521 M.O.

4th

year medical students


1 class: Neurobiology of

Opiates

Formal Teaching (Residents/Clinical and Research Fellows/Graduates/Undergraduates)

1988-1989 Psychology 101

Undergraduates

Queens College, City University of New York,

Flushing, NY

Taught 2 semesters, 2 classes per week

1991-1992 Neuroendocrinology

Arthur M. Fishberg Center for

Neurobiology

Mount Sinai School of Medicine, New York,

NY

Graduate students in

Neurobiology

Teaching Assistant, 2 semesters

2003, 2005 Cell Biology of Addiction

Cold Spring Harbor

Course Assistant

2008 Beth Israel Deaconess Medical

Center Psychiatry Residents

training in Neuroscience

Department of Psychiatry

Residents

Initiated and organized NEPRC tour and lecture

series presented by NEPRC Neuroscience

faculty. Presented 1 lecture: Comparable

Functional Polymorphisms in Rhesus Monkey

and Human Neuropsychiatric Genes

11

Teaching in Continuing Medical Education Courses

1997 Neurobiology of Addiction Boston, MA

CME: Treating the Addictions

Cambridge Health Alliance and Department of

Psychiatry, Harvard Medical School

2008 The Neurobiology and Genetic Susceptibility of

Addiction

Boston, MA

CME: Treating the Addictions.

Cambridge Health Alliance and Department of

Psychiatry, HMS

Ratings by 661 Attendees (mean):

Teaching ability: 3.56/4

Level of Knowledge: 3.84/4

The objective was met: 3.55/4

New Concepts Learned: 3.56/4

Training and Menotorship

1996-1997 Mentoring of an Endocrinology Resident

Joseph Pinzone, MD

Neuroendocrine Unit, MGH

Daily mentorship, 1 year

1997-1998 Menotoring and training of an Assistant

Professor

Larry Gracz, PhD

Division of Neurochemistry, NEPRC

Daily mentorship, two

consecutive summers

1997-2005 Mentoring of Postdoctoral Fellows:

Richard De La Graza, PhD

Martin Goulet, PhD

Jeffrey Brown, PhD

Servet Yatin, PhD

Danqing Xiao, PhD

Christopher Vericco, PhD

Amy Jassen, PhD

Over 8 years as Manager of

the Division of

Neurochemistry and

Instructor in Psychiatry, I

mentored seven postdoctoral

fellows; daily mentorship.

All seven have co-published

manuscripts with me.

1997-2005 Supervision and training of undergraduate

summer students,

NEPRC Summer Pre-Baccalaureate Program

Over 8 years, I supervised 2-

4 students per year.

2001- Training and mentoring of

graduate/medical/veterinary school-bound

Research Technicians

Mentored, trained and

published with post-

bachelorette technicians

12

Examples of mentoring of post-bachelorette research technicians: Reflects my strong

commitment to the academic advancement of post-bachelorette young adults who were hired as

research technicians in my lab.

1. Jacob Bendor, PhD Postdoctoral Fellow, UCSF Neurology

Trained at Rockefeller University with Paul Greengard

Summer student in my lab 2001 and 2002; Research Technician I in my lab 2003 and 2004

Publication: Miller GM, Bendor J, Tiefenbacher S, Yang H, Novak M, Madras BK. A Mu-opioid

receptor single nucleotide polymorphism in rhesus monkey: Association with stress response and

aggression. Molecular Psychiatry 2004; 9(1):99-108.

2. Sara Hakim Graduate Student, The Albert Einstein College of Medicine

Summer student in my lab 2005 and 2006; Research Technician I in my lab 2007 and 2008

Publications:

Chen GL, Novak MA, Hakim S, Xie Z, Miller GM. Tryptophan hydroxylase-2 gene

polymorphisms in rhesus monkeys: association with hypothalamic-pituitary-adrenal axis function

and in vitro gene expression. Molecular Psychiatry, 2006;11(10):914-28; Vallender EJ, Priddy

CM, Hakim S, Yang H, Chen G-L, Miller GM. Functional variation in the 3’ UTR of the

serotonin transporter in human and rhesus macaque. Genes, Brain and Behavior 2008;7(6):690-7.

3. Cassandra Priddy Graduate Student, Carnegie Mellon University

Research Technician I 2006-2007; Research Technician II 2007-2008

Publications: Vallender EJ, Priddy CM, Chen G-L, Miller GM. Human Expression Variation in

the mu Opioid Receptor is Paralleled in the Rhesus Macaque. Behavior Genetics,

2008;38(4):390-395; Vallender EJ, Priddy CM, Hakim S, Yang H, Chen G-L, Miller GM.

Functional variation in the 3’ UTR of the serotonin transporter in human and rhesus macaque.

Genes, Brain and Behavior 2008;7(6):690-7.

2005-2013 Supervision and training of undergraduate

summer students in my lab

NEPRC Summer Pre-Baccalaureate Program

>30 undergraduate summer

students were trained in my lab

over this period, averaging 6-

7/summer in 2009, 2010 2011

and 2012

Undergraduate students whom I have successfully financed with Foundation or NIH Awards:

1. Liz Calder (2006) Awarded an Irene and Eric Simon Brain Research Foundation Summer

Fellowship to work in my lab.

2: Kate Sullivan (2009) Funded with an NIH R21 Supplement 022323-02S1 to work in my

lab.

2007- Supervision and training of undergraduate

summer students in my lab in collaboration

with the Department of Psychology

University of Massachusetts, Amherst MA

One student accepted each

summer from the laboratories of

Drs. A. Lacreuse, J. Meyer or

M. Novak.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16847459&query_hl=1&itool=pubmed_docsum

http://carnegie-mellon.academia.edu/

13

2011 International:

Joint preparation of an International Brain Research Organization John G.

Nicholls Fellowship Application, “Modeling of Genetic Variations in Glutamate

Receptor NR1 in Rhesus Monkeys: A Translational Approach to Develop Novel

Pharmacological Agents for Treating Alcohol Dependence.” - and –

Joint preparation of a Branco Weiss Fellowship Application, “Modeling of

Genetic Variations in Glutamate Receptor Genes in Rhesus Monkeys: A Novel

Translational Approach to Develop Pharmacological Agents for Treating

Alcohol Dependence.”

for a postdoctoral fellowship in my lab for:

Kiran Kumar Akula Assistant Professor of Pharmacology

University Institute of Pharmaceutical Sciences

Panjab University, Chandigarh-160014, India

* Although neither application was funded, I was able to arrange for Dr. Akula

to receive a travel award from the College on Problems of Drug Dependence to

attend a satellite NIDA Mini-convention - Frontiers in Addiction Research, and

personally financed him further to attend the annual meeting of the Society for

Neuroscience, November, 2011 with our group.

Dr. Akula is now a Postdoctoral Fellow, Legacy Research, Portland, Oregon.

Formally Supervised Postdoctoral Trainees

2005-2013 Guo-lin Chen, PhD., Instructor in Psychiatry (promoted 12/13)

Division of Neuroscience, NEPRC, HMS

Postdoctoral Fellow, Miller Lab, NEPRC 2005-2013

15 publications in my lab/ 10 are first authorship

Co-I and major contributor; R21 DA030177 Epigenetic Regulation of

Serotonin: Relevance to HIV and Methamphetamine Abuse, 6/10-2/14

Winner of Best Paper in Neuroscience at NEPRC - 2012 Winner of the 3rdt

Annual Roger T. Kelleher Award for Excellence in Neuroscience and Behavior

for: Chen G-L and Miller GM. Advances in Tryptophan Hydroxylase-2 Gene

Expression Regulation: New Insights into Serotonin-Stress Interaction and

Clinical Implications. American Journal of Medical Genetics Part B:

Neuropsychiatric Genetics. Mar;159B(2):2012, 152-71.

2005-2012 Zhihua Xie, PhD., Independent Consultant, Biobanking Strategies

Research Associate, Division of Neuroscience, NEPRC


11 publications in my lab/ 7 are first authorship

Best paper in Neuroscience at NEPRC: 2010 Winner of the 1st Annual Roger T.

Kelleher Award for Excellence in Neuroscience and Behavior for: Xie Z and

Miller GM. A Receptor Mechanism for Methamphetamine Action in Dopamine

Transporter Regulation in Brain. J. Pharmacol. Exp. Ther. 2009;330(1):316-25.

1R21DA029733-01A1: Monoaminergic Mechanisms of Opioidergic Function

in Rhesus Monkey Brain. Xie, PI; not funded.

14

2006-2009

Eric J. Vallender, PhD., Assistant Professor in Psychiatry

Division of Neuroscience, NEPRC, HMS


Instructor, Miller Lab, NEPRC 2009-2012

>20 publications 2005-2013

Awarded NRSA MH082507, Modeling the Neurogenetics of Serotonin

Regulation 10/07-10/10

Awarded R01 AA019688 Functional Genetic Evolution of Human Brain and

Behavior, 8/10-7/15 Vallender-PI; Miller Co-I

Selected as an NEPRC “Super-Instructor” following a national search and given

an extensive laboratory start-up package

Promotion to Assistant Professor 6/12, Harvard Medical School

2009-2010 Spencer Lynn, PhD. Assistant Professor, Boston College, Dept. Psychology

Visiting Research Scientist, Northeastern University, Dept. Psychology

1 publication in my lab

Awarded R01 MH093394-01 The Utility of Threat Detection in Generalized

Social Anxiety Disorder: Score 14, percentile 6.0

Personal Statements from Postdoctoral Mentees not Formally Affiliated with my Lab

(unedited)

Michael Panas, Ph.D., Postdoctoral Fellow in the laboratory of Norman Letvin, Department of Medicine, Beth Israel

Deaconess Medical Center, Harvard Medical School.

1 publication coauthored with me: Panas MW et al. Trace Amine Associated Receptor 1 Signaling in Activated

Lymphocytes. Journal of Neuroimmune Pharmacology. 2012 In press.

Our work together was completely independent from his work with Dr. Letvin.

“I have known Dr. Miller since I did a lab rotation at the Harvard Primate Center as a summer student. We have kept in touch over the subsequent 5 years as I worked on my PhD in an Immunology lab at Harvard. In 2010 Dr. Miller approached me with exciting data that spanned both neuroscience and immunology and offered a collaboration that led to a manuscript. He opened his laboratory up to me: inviting me to meetings, allowing me to perform research in his lab, and inviting me to give presentations of the work generated in our collaboration. He has always made himself available for discussion, and always has constructive criticism on the experiments that I suggest. After I graduated, Dr. Miller has taken special effort to augment the skills that I will need as a successful post doctoral candidate. He emphasizes a comprehensive understanding of the literature, and I often find emails from him with relevant papers attached. He has also given me opportunities to familiarize myself with the grant system through allowing me assist in the writing process of two of his grants. In the past year, my PhD adviser has been battling cancer, and Dr. Miller has stepped up and been a wonderful surrogate adviser. Most importantly, he has been a guiding light as I applied to post doctoral positions. He has taken the time to listen and discuss with me my goals, so that I knew what to look for in a lab. He has even gone so far as to personally communicate with my potential future PIs. Ultimately, in part because of his assistance, I found a lab at Stanford University that fits my interests and I will begin there in September 2012. I cannot emphasize enough the excellent support and mentoring that Dr. Miller has contributed to my career. I am grateful for my opportunity to collaborate and publish with him, and I hope that he will continue to guide me in my career as a post doctoral fellow.”

Michael Panas, Ph.D.

15

Cindy Achat-Mendes Ph.D., Postdoctoral Fellow in the laboratory of Roger Spealman at NEPRC.

1 publication coauthored with me: Achat-Mendes e al. Augmentation of methamphetamine-induced behaviors in

transgenic mice lacking the trace amine-associated receptor 1. Pharmacol Biochem Behav. Apr;101(2):201-207, 2012.

Our work together was completely independent from her work with Dr. Spealman.

“Dr. Gregory Miller has been one of my most supportive and inspiring colleagues. Our relationship began when Dr. Miller introduced me to a class of receptors (trace amine associated receptors; TAAR1) that was novel to the area of drug addiction research. Based on our mutual scientific interests, Dr. Miller encouraged me to pursue my interests in methamphetamine reward in his laboratory. Our collaboration involved investigating the role of TAAR1 on abuse-related behaviors of methamphetamine. In particular, Dr. Miller helped me interpret our findings in the context of receptor mechanisms involved in methamphetamine’s neurochemical effects. Dr. Miller facilitated the presentation of our findings at the Society for Neuroscience by providing me with financial support for this meeting. This scientific collaboration culminated in the successful publication of our manuscript entitled “Augmentation of methamphetamine-induced behaviors in transgenic mice lacking the trace amine-associated receptor 1” which was published in the journal Pharmacology, Biochemistry and Behavior. Dr. Miller has been supportive also of my scientific endeavors that do not pertain to TAAR1. Over the past years he has encouraged me to attend and participate in various conferences and meetings that would benefit my postdoctoral experience. For example, he recommended me for participation in a Cold Spring Harbor Laboratory workshop on Learning and Memory for which I was accepted. He also recommended me for membership to the College of Problems and Drug Dependence for which he is now a Board Member. As a mentor, Dr. Miller’s best qualities are his approachable and enthusiastic attitudes. He has earnestly and willingly mentored me in areas of grantsmanship and in the opportunities and challenges of the postdoctoral position. Importantly, he has shared his positive and negative experiences as a Postdoctoral Fellow and Assistant Professor which has afforded me a depth of understanding that will no doubt benefit my transition from Postdoctoral Fellow to Assistant Professor.”

Cindy Achat-Mendes Ph.D.

Spencer Lynn Ph.D., Research Associate (now an Assistant Professor), Department of Psychology, Northeastern

University

2 publications coauthored with me: Karmacharya et al. Behavioral effects of clozapine: Involvement of trace amine

pathways in C. elegans and M. musculus. Brain Research 2011, Jun 1;1393:91-9.

Panas H et al. Normal thermoregulatory responses to 3-iodothyronamine, trace amines and amphetamine-like

psychostimulants in trace amine associated receptor 1 knockout mice. Journal of Neuroscience Research

2010;88(9):1962-9.

Awarded R01 MH093394-01 The Utility of Threat Detection in Generalized Social Anxiety Disorder: Score 14,

percentile 6.0

“Dr. Miller operates on the principal that generosity of spirit enables generativity of ideas. He is tremendously outgoing, generous, and supportive as a mentor. He supplemented my training far beyond our initial collaboration. For example, he invited me to take an oversight role within his mouse laboratory, he encouraged me to develop techniques in his laboratory that were novel to both of us, and he welcomed my contribution to on-going studies outside of our initial collaboration. He supported my attendance and presentation at a national conference (Society for Neuroscience) and shared his advice and perspective on managing personnel and on scientific conduct. Our work together led to two peer-reviewed publications and an R21 application to NIMH. In these concrete ways, Greg has made a strong impact on my professional development, and I am a better scientist for it. I greatly appreciate the opportunities I had to develop skills and pursue ideas under his mentorship.”

Spencer K. Lynn, Ph.D.

Koji Yasuda M.S, DVM, Postdoctoral Fellow/Pathology Resident, Division of Comparative Pathology, NEPRC and 1st

year Ph.D. Student in Biomedical Sciences and Public Health in the Graduate School of Arts and Sciences, Harvard

University.

“My name is Koji Yasuda and I am a research fellow/pathology resident in the division of comparative pathology at the New England Primate Research Center. I was introduced to Greg in April of this year by my division’s acting chair Susan Westmoreland in regards to our interests in bringing the microbiome and metabolomic research to the primate

http://www.ncbi.nlm.nih.gov/pubmed/22079347


16

center. Since then Greg has introduced me to various investigators at the center as well as other institutions (Broad Institute, MIT Neuroscience, Metabolon Inc.), and guided me to attend a metabolomic workshop and a microbiome webinar that has enabled us to move forward on the microbiome/metabolomic research. Greg is also currently guiding me with writing a primate center based grant, and we will work together to prepare a manuscript on our initial microbiome/metabolomic study that is currently underway. Greg’s mentorship and guidance has been and will continue to be an essential part of my professional development. I admire Greg’s outstanding scientific wisdom and vision for the future in science and the society.”

Koji Yasuda M.S, DVM

Fumiaki Yoshida M.D., Ph.D., Postdoctoral Fellow, MIT Media Lab, McGovern Institute for Brain Research at MIT

“Since meeting at the Neuroscience 2011 (November, Wasington DC), I was given an intensive mentorship from Professor Miller. Although I am a postdoctoral associate at “MIT” not at “Harvard”, he kindly invites me to have once a month personal meeting at the New England Primate Research Center other than online communication. He keeps advising me about how to produce valuable scientific results as well as how to develop my professional career with full of real enthusiasm. He thoughtfully assisted my NIH K99 carrier development award application. During our scientific discussion, his comments from pharmacological aspects are also precious for a person who does not have background in this area like me. I have been learning at Kyushu University- Japan, University College London, University of Oxford- UK and MIT- USA but no one has been comparable to him as a mentor. I am really fortunate to have met him and I will definitely hope to maintain this relationship for all my life.”

Fumiaki Yoshida M.D., Ph.D.

Kiran Kumar Akula M.Pharm, Ph.D., Assistant Professor of Pharmacology, University Institute of Pharmaceutical

Sciences, Panjab University, Chandigarh, India. Currently: Postdoctoral Fellow, Legacy Research, Portland, Oregon.

Dr. Akula was attracted to my research program and after several communications I decided to help him with two

international grant applications. With my assistance, Dr. Akula received a travel award from the College on Problems of

Drug Dependence to attend the NIDA Mini-convention - Frontiers in Addiction Research. I financed and arranged for

him to also attend the annual meeting of the Society for Neuroscience, November 11, 2011, and to meet and reside with

my lab group during that meeting.

“I feel honored to write about Dr. Miller, a pioneer in the field of addiction research spanning pharmacogenomics and primate research. We worked together in preparing a couple of research grants and I was indeed fortunate to get that chance to learn from his meticulous writing skills in presentation of all the current scientific facts elegantly with his efficiency in substance abuse research. His eclectic mentorship, punctuality, timely efforts in meeting deadlines and overall, his ability to put a productive team together are commendable. He was highly considerate in encouraging and helping ambitious students like me in our participation in scientific conventions like Neuroscience2011, held in Washington DC. His impeccable personality makes him go well with all his peers and in my association I found him as one of my best mentors, leading by example and as a compassionate human being. I strongly support his personality and expertise for the promotion to Associate Professor and beyond".

Kiran Kumar Akula M.Pharm, Ph.D.

Personal Statements from Undergraduate Students Whom I Have Mentored (unedited)

Students were formally accepted into the highly competitive New England Primate Research Center Summer

Undergraduate Training Program (SUTP).

“My experience at the New England Primate Research Center during the summer of 2010 proved one of the most interesting, challenging, and enjoyable experiences of my life. Working in the Greg Miller lab, I was given a great amount of attention and the opportunity to collaborate on the lab’s highest priority projects. With the entire lab staff as mentors, I was able to learn many techniques and conduct on my own, PCR, bacteria growth, plasmid DNA, cell growth and transfection, RNA isolation, and run multiple complete assays. In the end, I was able to produce a poster that highlighted the major project I had been working on throughout the summer with Eric Vallender, exploring the differences in expression of MAOA across multiple primate species. Though this was an unbelievable hands-on

17

experience, I was also encouraged to think critically about data, research past and present experiments, and explore ideas of my own. I was given the resources – both, the support of my mentors and scientific materials – to learn and grow as an individual in the scientific and academic worlds. Before my experience at the NEPRC, I had little background in laboratory science, but with the excellent mentorship of this program, I have gained the skills necessary to continue lab work and collaboration, as well as the confidence to research and bring forth ideas of my own.”

Paul Antion, Washington University in St. Louis ’12 (Blue Ventures Education Coordinator) “I want to express my appreciation for giving me the opportunity to work at the NEPRC this summer. Thank you for taking me on-board as an intern, for overseeing my projects, for providing endless help and support, and for a truly awesome experience. I am strongly reconsidering a career in research, as I now realize the extent of variation that exists between different labs. Working at the NEPRC this summer surprised me. A collaborative work environment and variety of research projects made for a stimulating and enjoyable day-to-day experience. An internship at the NEPRC is a window into question-based science; it’s an opportunity to experience truly investigative research and apply your coursework. From cell culture to bioinformatics, it taught me that the best research strives to not only further our understanding, but also address real diseases and disorders afflicting society. Unlike other research labs I have worked in, the NEPRC allowed me to initiate and mold my own projects. In a summer spent with the NEPRC, you may or may not “discover a novel nonsynonymous single-nucleotide polymorphism,” but you’ll definitely discover what it means to do research in a place with more resources than you have time to take advantage of. I am so grateful that I was accepted to work at the NEPRC this summer, and I will miss the joy of working with its people as much as its energy of discovery.”

Erin Sadler, William and Mary, ’12 (Accepted to Eastern Virginia Medical School in Norfolk, VA, 2013) Comments from the High School graduates that I selected and hired as temporary employees:

Personal Statements from Incoming College Freshman Whom I Have Mentored (unedited)

I had a strong interest in providing an unprecedented opportunity for up to three top-performing new High School

graduates to have a summer internship experience in my lab, which was denied by the NEPRC administration. A rule

was set forth at that time that all SUTP interns must have completed their freshman year of college. I circumvented this

policy by hiring three local High School students, whom were all 18 years old, as temporary employees to work in my

lab. I originated a recruitment strategy aimed at high school science department heads. I recruited three of the most

outstanding students from local high schools. These students were integrated with and treated the same as students who

were formally accepted into the SUTP program.

“The guidance that I have received as part of my experience at the New England Primate Research Center Division of Neurochemistry has been extremely valuable. I have conducted a wide variety of projects here- including analyzing scientific articles and grants, finding single nucleotide polymorphisms, making cDNA out of RNA from two different brain regions, finding which genes relate to neurotoxicity, and using the Lightcycler machine to find changes in gene expression due to TAAR1 and also to do melt curve genotyping of the OPRM gene. My co-workers have exposed me to an even greater variety of projects; working with the other summer interns has been extremely beneficial and collaborating on our research presentation poster session has been a significant culminating experience. Creating graphs, abstracts, and reports has helped me not only with presenting my summer research, but this learning experience will help me with any future project that I choose to take on. It is fascinating to learn how our research can benefit society and how determining the role of the particular gene that I am researching relates to neurotoxicity and in turn, can lead to improved personalized medicine and smarter drug development. This unique, exciting opportunity has further fueled my interest in research and medicine- it has already led me to apply for a Genome Revolution focus group at Duke and furthered my plans to major in neuroscience. I now have a strong skill set to bring with me to college and as a neuroscience major, this experience will be invaluable. The people here have really been mentors to me on my path to a scientific career. The New England Primate Research Center has abundant resources and as a summer intern, I was even able to attend lectures by Harvard faculty members. I have received phenomenal guidance and advice from my mentor and co-workers. I am extremely grateful to Greg Miller for providing me with the opportunity to intern at the New England Primate Research Center.”

Alexandra Young, Duke University ‘15

18

“I entered my summer term at the NEPRC without an adequate understanding of what the life of a scientist is like. High school biology courses and Hollywood portrayals of scientists had left me with a skewed perception of what a career in research entailed. In fact, it is near impossible to accurately comprehend the lifestyle of a scientist and the inner workings of the research and funding process until one jumps into the fray and works right alongside minor or leading scientists of the day. And that is exactly what the NEPRC provides, an opportunity to taste a career in research in any one of a multitude of fields. I know that for me, about to enter college at UVA, having a sense of what it would mean to pursue a career in research is incredibly valuable. It helps me decide if such a career is really what I want, or if I would rather pursue other interests. In turn, that brings some order to the chaotic scene of course selection, which, especially for a freshman, is a daunting task. Of course, a summer internship at the NEPRC has a substantial academic value as well. My experience here has been more hands on than anything I could have imagined in high school. The independence given in designing and executing projects is phenomenal, and unparalleled by any other institution offering a similar position to summer students. As such, learning here does not revolve around textbook memorization, but rather personal discovery and firsthand involvement. At the NEPRC, you are only restricted by the limits of your own drive and initiative. I give this experience my highest recommendation.”

Jonathan Weinstein, U. Virginia ‘15

“This summer has been such a growing and learning experience and I couldn’t be happier that I took this opportunity. It was the first time I was able to actively be a part of the “real world” and do something worthwhile. Having the chance to receive training at a prestigious research lab before beginning my undergraduate education is not something very common and will be looked highly upon by future professors and employers. Having this internship challenged me in how to be more of an independent thinker. I was given the chance to work on my own projects and obtain data, which I then learned how to interpret and analyze. With the data received I was able to go through the process of investigating whether future experiments can be completed based on my results. Not only was I able to practice working as an independent thinker, I was also able to learn how to better work as a member of a collaborative group. Working at a research lab is unlike any other job a person my age could ever experience- especially this particular lab. I was given the ability and tools to learn anything I wanted to if I took the initiative. Working at this lab taught me that there are always resources to assist you in life; it’s just up to you to figure out what to do with those resources- if you do anything at all. Good opportunities can appear in life, but it’s up to the individual to be proactive and take advantage of them or sit around and watch them slip away. Leaving this lab, I can still say that I am not quite sure what I want to do in life, but even if I don’t further my education in the science or research direction, I have learned valuable lessons this summer that will carry with me through the rest of my life.”

Ashley Reynolds, Skidmore ‘15

Report of Local, Regional, National and International Invited Scientific

Presentations

Local

2000 Molecular Approaches to Attention Deficit Hyperactivity Disorder

NEPRC Summer Internship Program

New England Primate Research Center, Southborough, MA

2002 Genes and Drug Addiction



2002 Point mutations of the human dopamine transporter reveal differential binding of

an amine and a nonamine ligand

Neuroscience Seminar Series

McLean Hospital, Belmont, MA

19

2003 Genetic Diversity of Drug Targets in the Brain



2004 Genetic Variations and Phenotypic Associations Common to Rhesus Monkeys

and Humans

New Faculty Search Seminar


2005 Rhesus Monkey Models in Neurobiology, Neuropsychiatry and AIDS

Boston University-NEPRC symposium


2005 Naturalistic Modeling of Human Functional Polymorphisms in Rhesus Monkeys

Research Symposium


2008 What are the Roles of Trace Amine-Associated Receptor 1 in Primates?

Division of Behavioral Biology, NEPRC


2008 Trace Amine Receptor 1 in Brain Monoaminergic Systems

Division of Comparative Pathology


2008 Trace Amine Associated Receptor 1 in Brain Monoaminergic Systems



2008 The Neurobiology and Genetic Susceptibility of Addiction



2008 Comparable Functional Polymorphisms in Rhesus Monkey and Human

Neuropsychiatric Genes

The Behavioral Genetics Laboratory


2011 Drug addiction research at the New England Primate Research Center

Division of Primate Resources Animal Care Staff


2011 The Biogenic Amine/Amphetamine Receptor TAAR1: What’s It Doing in Brain

Monoaminergic Systems?



20

2013

Models of polygenetic psychiatric and addictive disorders

Grand Rounds

Center for Addiction Medicine

Massachusetts General Hospital, Boston, MA

Report of Regional, National and International Invited Teaching and

Presentations

No presentations below were sponsored by outside entities

2008 Trace Amine-Associated Receptor 1 in Brain Monoaminergic Systems

Invited Speaker, Boston University Medical School, Boston, MA

2009 The Neurobiology and Genetic Susceptibility of Addiction

Invited Speaker

Summer Undergraduate Research Fellowship (SURF) Program Seminar Series

The Massachusetts College of Pharmacy and Health Sciences, Boston, MA

2010 The Role of TAAR1 in Monoamine Transporter Regulation and Methamphetamine

Action

Invited Speaker, Center for Drug Discovery Annual Symposium

Northeastern University, Boston, MA

2013 Trace Amine Associated Receptor 1 in the Monoamine System and its Role in

Modulating the Effects of Drugs of Abuse

Invited Speaker, Department of Pharmaceutical Sciences

Bouvé College of Health Sciences


2014 TAAR1 and Drugs of Abuse

Invited Speaker, Center for Drug Discovery Annual Symposium


National

1999 Point mutations in the human dopamine transporter reveal differential binding

of an amine and a non-amine ligand

Oral presentation/ selected abstract

Society for Neuroscience Annual Meeting, Miami Beach, Florida

2000 Single Nucleotide Polymorphisms Distinguish Multiple Dopamine Transporter

Alleles in Primates: Implications for Association With ADHD and Other

Neuropsychiatric Disorders


Society for Neuroscience Annual Meeting, New Orleans, Louisiana

21

2001 Genetic Diversity of Drug Targets in the Brain: Relevance to Drug Response?,


College on Problems of Drug Dependence Annual Meeting, Scottsdale,

Arizona.

2001

Single Nucleotide Polymorphisms Distinguish Multiple Dopamine Transporter

Alleles in Primates

Cold Spring Harbor Laboratory

Cold Spring Harbor, NY

2002 Cloning of rhesus monkey TAR-1, a novel GPCR for “trace” amines


Society for Neuroscience Annual Meeting, Orlando, Florida

2003 A Mu-opioid Receptor Single Nucleotide Polymorphism in Rhesus Monkey:

Association With Stress Response And Aggression


Society for Neuroscience Annual Meeting, New Orleans, Louisiana

2003 Genetic Variations And Phenotypic Associations Common To Rhesus

Monkeys And Humans

Invited Presentations

Cell Biology of Addiction Course

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

2006 Rhesus monkey Trace Amine Receptor 1

Invited Presentation

Lundbeck Research USA Inc., Mahwah, NJ

2006

Neurobiology and Physiogenetics of Neuropsychiatric


NCRR Workshops on the Rhesus Monkey Genome, NIH, Bethesda, MD

2006

Trace amine receptor 1 in Brain Monoaminergic Systems


Eli Lilly, Indianapolis, IN

2007 Using non-human primates to model the genetics of human neuropsychiatric

Disorders


NCRR Workshops on the Rhesus Monkey Genome, NIH, Bethesda, MD

2008

Developing Non-Human Primate Genetic Models of Human Neuropsychiatric

and Addictive Disease


Society for Neuroscience Annual Meeting, Washington, DC

22

2008 Session 314.Stress, depression and monoamines

Session Chair

Society for Neuroscience Annual Meeting, Washington, DC

2008 What are the Roles of Trace Amine Associated Receptor 1 in Primates?

Session Organizer and Invited Presentation

The 41st Winter Conference on Brain Research, Snowbird, UT

2008 Trace Amine-Associated Receptor 1 in Brain Monoaminergic Systems

Selected by the Department of Physiology & Pharmacology Graduate Students

as the annual invited speaker

Oregon Health & Science University, Portland, OR

2008 Monkey Genes Come in Human Flavors: Translational Models of Human

Neuropsychiatric and Substance Abuse Disorders in Rhesus Monkeys

Invited by the APA Committee on Animal Research and Ethics

The 116th

Annual Meeting of the American Psychological Association

Boston, MA

2009 Non-Human Primate Genetic Models of Human Neuropsychiatric and

Addictive Disease. The Behavioral Genetics of Co-Morbidity: More Than Just

Overlapping Phenotypes

Invited NIDA-sponsored Presentation

The 42st Winter Conference on Brain Research, Copper Mountain, CO

2009 Trace Amine-Associated Receptor 1 (TAAR1) as a Monoaminergic Modulator


Oregon National Primate Research Center, Beaverton, OR

2010 Oral Communications Session 16. Transmitting Information on Serotonin

Session Chair

College on Problems of Drug Dependence Annual Meeting, Scottsdale,

Arizona.

2011

Advancing the Rhesus Monkey Model for Opioid Research: Discovery of a

Novel Nonsynonymous Variant in the Kappa Opioid Receptor Gene


College on Problems of Drug Dependence Annual Meeting, Hollywood,

Florida

2011 Oral Communications 2 Genetics: Code Read

Session Chair

College on Problems of Drug Dependence Annual Meeting, Hollywood,

Florida

23

2011 The Biogenic Amine/Amphetamine Receptor TAAR1: What’s It Doing in

Brain Monoaminergic Systems?


Department of Physiology

Emory School of Medicine, Atlanta, GA

2013 Trace Amine Associated Receptor 1 in the Monoamine System and its Role in

Modulating the Effects of Drugs of Abuse.


Dept. Integrative Physiology and Neuroscience

College of Veterinary Medicine

Washington State University, Pullman, WA

2013

Studies on Trace Amine Associated Receptor 1


TMED - Translational Medicine & Early Development

Sunovion Pharmaceuticals Inc.

Marlborough, MA

2013 Trace amine-associated receptor 1 is a methamphetamine receptor that

differentially controls DAT and NET internalization


Symposium XIII: New Tools Provide New Insights Into Methamphetamine’s

Actions

College on Problems of Drug Dependence Annual Meeting

San Diego, CA

2013 Trace amine associated receptor 1 modulation of the rewarding and

immunological effects of drugs of abuse supports its relevance as a therapeutic

target.

Invited Speaker

Session Chair

Panel Session 1. Kicking Over the Traces

Noncatecholic Biogenic Amines and Their Receptors

American College of Neuropsychopharmacology

52nd Annual Meeting

Hollywood, Florida

International

2002 Genetic Diversity of Drug Targets in the Brain: Similarities Between Human

and Rhesus Monkey m-Opioid Receptor Variants


College on Problems of Drug Dependence

Quebec City, Quebec, Canada

24

2005 Rhesus monkeys as naturalistic models for deciphering genotype/phenotype

relationships relevant to human neuropsychiatric disorders

Invited Session Speaker

The 2nd

International Conference on Primate Genomics & Human Disease

Seattle, Washington.

2008 Comparable functional polymorphisms in rhesus monkeys and human

neuropsychiatric genes


The 3nd


Seattle, Washington.

2010 Translational Genetic and Pharmacogenomic Modeling of Human

Neuropsychiatric and Drug Addiction Phenotypes

Program Committee Member and Invited Session Speaker

The 4th


Seattle, WA

2010 Session 3. Primate Genomics and AIDS

Session Chair

The 4th


Seattle, WA

2010 The TAAR1 Receptor Orchestrates Trace Amine, Common Biogenic Amine

and Psychostimulant effects in Brain Monoaminergic Systems


The 14th

Biennial International Amine Oxidase Workshop

Edmonton, Alberta, Canada

2011 Exploiting the Parallel Functional Polymorphisms and Pharmacogenomic

Responsivity Between Rhesus Monkeys and Humans for Drug Discovery:

A New Avenue for Preclinical Modeling to Advance Personalized Medicine for

Psychiatric and Addictive Disease.

Target Meeting 1st World Drug Discovery Online Conference

http://www.targetmeeting.com

2012 Session 2. Genomic and Primate Models of Health and Disease

Session Chair

The 5th


Houston, TX

2012 A Systematic Phenotyping Strategy to Transform the Use of Rhesus Monkeys

in Biomedical Research


The 5th


Houston, TX

25

2012 Trace Amine Associated Receptor 1 is a Catecholamine Receptor that

Differentially Controls DAT and NET Internalization


Theme B. Catecholamine Transporter Genetics

The Tenth International Catecholamine Symposium, Pacific Grove, California

2013 Trace Amine Associated Receptor 1 (TAAR1) Signaling Differentially

Regulates Dopamine and Norepinephrine Transporter Internalization

Invited Symposium Speaker

Session: Anatomy and physiology of dopamine systems

Topic: New Mechanisms by Which Trace Amine-Associated Receptors

Modulate Dopamine Neuron Activity

Dopamine 2013, Alghero, Italy

Report of Education of Patients and Service to the Community

Activities

2010- 2013 Member, Executive Committee

2013- Member, Board of Directors

Community Connections Outreach on Substance Abuse

Sudbury, Massachusetts

2012 Organizer, “What were you thinking?”

Presentation of the teen brain

Lincoln Sudbury Regional High School

Sudbury, Massachusetts

Report of Scholarship

Peer reviewed publications in print or other media

1. Gibson MJ, Miller GM, Silverman A-J. Pulsatile luteinizing hormone secretion in normal

female mice and hypogonadal female mice with preoptic area implants. Endocrinology

1991;128:965-71.

2. Wu TJ, Segal AZ, Miller GM, Gibson MJ, Silverman A-J. FOS expression in gonadotropin-

releasing hormone neurons: enhancement by steroid treatment and mating. Endocrinology

1992;131:2045-50.

3. Silverman A-J, Roberts JL, Dong KW, Miller GM, Gibson MJ. Intrahypothalamic injection

of a cell line secreting gonadotropin-releasing hormone results in cellular differentiation and

reversal of hypogonadism in mutant mice. Proceedings of the National Academy of Sciences

(USA) 1992;89:10668-72. PMCID: PMC50402

26

4. Miller GM, Silverman A-J, Roberts JL, Dong KW, Gibson MJ. Functional assessment of

intrahypothalamic implants of immortalized gonadotropin-releasing hormone secreting cells in

female hypogonadal mice. Cell Transplantation 1993;2(3):251-7.

5. Miller GM, Gibson MJ. Opioidergic modulation of N-methyl-D,L-aspartic acid (NMA)-

stimulated LH release in young adult but not older male mice. Neuroendocrinology 1994;59:277-

84.

6. Miller GM, Silverman A-J, Gibson MJ. Neuromodulation of transplanted GnRH neurons in

male and female hypogonadal mice with preoptic area brain grafts. Biology of Reproduction

1995;52:572-83.

7. Miller GM, Alexander JM, Bikkal HA, Katznelson L, Zervas NT, Klibanski A. Somatostatin

receptor subtype gene expression in pituitary adenomas. Journal of Clinical Endocrinology and

Metabolism 1995;80:1386-92.

8. Miller GM, Alexander JM, Klibanski A. Gonadotropin-releasing hormone mRNA expression

in gonadotroph tumors and normal human pituitary. Journal of Clinical Endocrinology and

Metabolism 1996;81:80-3.

9. Gibson MJ, Wu TJ, Miller GM, Silverman A-J. What nature's knockout teaches us about

GnRH Activity: Hypogonadal mice and neuronal grafts. Hormones and Behavior

1997;31(3):212-220.

10. Madras BK, Miller GM, Meltzer PC, Brownell A-L, Fischman AJ. Molecular and regional

targets of cocaine in primate brain: liberation from prosaic views. Addiction Biology

2000;5:351-9.

11 Miller GM, De La Garza R, Novak MA, Madras BK. Single nucleotide polymorphisms

distinguish multiple dopamine transporter alleles in primates: Implications for association with

attention deficit hyperactivity disorder and other neuropsychiatric disorders. Molecular

Psychiatry 2001;6:50-8.

12 Miller GM, Yatin SM, De La Garza R, Goulet M, Madras BK. Cloning of dopamine,

norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity.

Molecular Brain Reserach 2001;87(1):124-43.

13 Goulet M, Miller GM, Bendor J, Liu S, Meltzer PC, Madras BK. Non-amines, drugs without

an amine nitrogen, potently block serotonin transport: novel antidepressant candidates? Synapse

2001;42:129-40.

14 Miller GM, Madras BK. Polymorphisms in the 3’-untranslated region of human and monkey

dopamine transporter genes affect reporter gene expression. Molecular Psychiatry 2002;7(1):44-

55.

15 Madras BK, Miller GM, Fischman AJ. The dopamine transporter: Relevance to attention

deficit hyperactivity disorder (ADHD). Behavioral Brain Research 2002;130(1-2):57-63.

27

16 Yatin SM, Miller GM, Norton C, Madras BK. Dopamine transporter-dependent and –

independent c-fos induction by dopamine transporter substrates and inhibitors. Synapse

2002;45(1):52-65.

17 Madras BK, Fahey MA, Miller GM, De La Garza R, Spealman RD, Meltzer PC, George SR,

O’Dowd BF, Bonad AA, Livni E, Fischman AJ. Non-amine based dopamine transporter

(reuptake) inhibitors retain properties of amine-based progenitors. European Journal of

Pharmacology 2003;479:41-51

18 Miller GM, Bendor J, Tiefenbacher S, Yang H, Novak M, Madras BK. A Mu-opioid receptor

single nucleotide polymorphism in rhesus monkey: Association with stress response and

aggression. Molecular Psychiatry 2004;9(1):99-108.

19 Madras BK, Miller GM, Yatin SM. Dopamine and norepinephrine transporter-dependent

immediate early gene production in vitro: new insights into psychostimulant-induced presynaptic

neuroadaptation. Journal of Neuroscience Methods 2005;143(1):69-78.

20 Madras BK, Miller GM, Fischman AJ. The Dopamine Transporter and Attention Deficit

Hyperactivity Disorder (ADHD). Biological Psychiatry 2005;57(11):1397-1409.

21 Jassen AK, Brown JM, Panas HN, Miller GM, Xiao D, Madras BK. Variants of the primate

vesicular monoamine transporter-2. Molecular Brain Research 2005;139(2):251-7.

22 Yatin SM, Miller GM, Madras BK. Dopamine and norepinephrine transporter-dependent c-

Fos production in vitro: relevance to neuroadaptation. Journal of Neuroscience Methods

2005;143(1):69-78. 23. Miller GM, Verrico CD, Jassen A, Konar M, Yang H, Panas H, Bahn M, Johnson R and

Madras BK. Primate trace amine receptor 1 modulation by the dopamine transporter. Journal of

Pharmacology and Experimental Therapeutics 2005;313(3):983-994.

24. Xiao D, Miller GM, Jassen AK, Westmoreland SV, Pauley D, Madras BK. Ephrin/Eph

Receptor Expression in Brain of Adult Nonhuman Primates: Implications for Neuroadaption.

Molecular Brain Research, 2006;1067(1):67-77.

25. Jassen AK, Yang H, Miller GM, Calder E, Madras BK. Receptor regulation of axon

guidance molecule gene expression. Molecular Pharmacology 2006;70(1):71-7.

26. Kumar, R, Orsoni1 S, Norman1 L, Tirado1 G, Verma1 AS, Staprans S, Miller G, Buch SJ,

Kumar A. Morphine Addiction Causes Pronounced Virus Replication in Cerebral Compartment

and Accelerated Onset of AIDS in SIV/SHIV-infected Indian Rhesus Macaques. Virology

2006;354(1):192-206.

27. Chen GL, Novak MA, Hakim S, Xie Z, Miller GM. Tryptophan hydroxylase-2 gene

polymorphisms in rhesus monkeys: association with hypothalamic-pituitary-adrenal axis

function and in vitro gene expression. Molecular Psychiatry 2006;11(10):914-28.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16847459&query_hl=1&itool=pubmed_docsum

28

28. Madras BK, Xie Z, Lin Z, Jassen AJ, Panas H, Lynch L, Johnson RS, Livni E, Spencer TJ,

Bonab AA, Miller GM, Fischman AJ. Modafinil Occupies Dopamine and Norepinephrine

Transporters in vivo and Modulates the Transporters and Trace Amine Activity in vitro. Journal

of Pharmacology and Experimental Therapeutics 2006;319(2):561-9.

29. Newman RM, Hall L, Connole M, Chen G-l, Sato S, Yuste E, Diehl W, Hunter E, Kaur A,

Miller GM and Johnson WE. Balancing selection and the evolution of functional polymorphism

in old world monkey trim5alpha. Proceeding of the National Academy of Science (USA),

2006;103(50):19134-9. PMCID: PMC1679755

30. Verrico CD, Miller GM, Madras BK. MDMA (Ecstasy) and Human Dopamine,

Norepinephrine and Serotonin Transporters: Implications for MDMA-Induced Neurotoxicity and

Treatment. Psychopharmacology 2007;189(4):489-503.

31. Xie, Z, Westmoreland S, Bahn ME, Chen G-L, Yang H, Vallender E, Yao WD, Madras BK,

Miller GM. Rhesus monkey trace amine-associated receptor 1 signaling: enhancement by

monoamine transporters and attenuation by the D2 autoreceptor in vitro. Journal of

Pharmacology and Experimental Therapeutics 2007;321(1):116-27.

32. Xie Z and Miller GM. Trace Amine-Associated Receptor 1 is a Modulator of the Dopamine

Transporter. Journal of Pharmacology and Experimental Therapeutics 2007;321(1):128-36.

33. Zhang JP, Vinuela A, Neely MH, Grant SG, Miller GM, Isacson O, Caron MG, Yao WD.

Inhibition of the Dopamine D1 Receptor Signaling by PSD-95. Journal of Biological Chemistry.

2007;282(21):15778-89. PMCID: PMC2649122

34. Chen GL and Miller GM. Rhesus Monkey Tryptophan Hydroxylase-2 Coding Region

Haplotypes Affect mRNA Stability. Neuroscience 2008;155(2):485-91. PMCID: PMC2644555

35. Chen G-L, Vallender EJ, Miller GM. Functional Characterization of the Human TPH2 5'

Regulatory Region: Untranslated Region and Polymorphisms Modulate Gene Expression In

Vitro. Human Genetics 2008;122(6):645-57. PMCID: PMC2734478

36. Lee AS, Gutierrez-Arcelus M, Perry GH, Vallender EJ, Johnson WE, Miller GM, Korbel JO

and Lee C. Analysis of copy number variation in the rhesus macaque genome identifies

candidate loci for evolutionary and human disease studies. Human Molecular Genetics 2008;

17(8):1127-36.

37. Xie Z and Miller GM. -Phenylethylamine Alters Monoamine Transporter Function via

Trace Amine-Associated Receptor 1: Implication for Modulatory Roles of Trace Amines in

Brain. Journal of Pharmacology and Experimental Therapeutics 2008;325(2):617-628.

38. Xie Z, Westmoreland SV, Miller GM. Modulation of Monoamine Transporters by Common

Biogenic Amines via Trace Amine-Associated Receptor 1 and Monoamine Autoreceptors in

HEK293 Cells and Brain Synaptosomes. Journal of Pharmacology and Experimental

Therapeutics 2008;325(2):629-640.

39. Vallender EJ, Priddy CM, Chen G-L, Miller GM. Human Expression Variation in the mu

Opioid Receptor is Paralleled in the Rhesus Macaque. Behavior Genetics 2008;38(4):390-395.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Madras+BK%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Xie+Z%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Lin+Z%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Jassen+AJ%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Panas+H%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Lynch+L%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Johnson+RS%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Livni+E%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Spencer+TJ%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Bonab+AA%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Miller+GM%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Fischman+AJ%22%5BAuthor%5D

29

40. Vallender EJ, Priddy CM, Hakim S, Yang H, Chen G-L, Miller GM. Functional variation in

the 3’ UTR of the serotonin transporter in human and rhesus macaque. Genes, Brain and

Behavior 2008;7(6):690-7.

41. Xie Z, Vallender EJ, Yu N, Kirstein S, Yang H, Bahn M, Westmoreland SV, Miller GM.

Cloning, expression and functional analysis of rhesus monkey trace amine-associated receptor 6:

Evidence for lack of monoaminergic association. Journal of Neuroscience Research

2008;86(15):3435-46. PMCID: PMC2644554

42. Verrico CD, Lynch L, Fahey MA, Fryer A-K, Miller GM and Madras BK. MDMA-induced

impairment in primates: antagonism by a selective norepinephrine or serotonin, but not by a

dopamine/norepinephrine transport inhibitor. Journal of Psychopharmacology 2008;22(2):187-

202.

43. Vallender EJ, Lynch L, Novak MA, Miller GM. Polymorphisms in the 3' UTR of the

serotonin transporter are associated with cognitive flexibility in rhesus macaques. American

Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2009;150B(4):467-75. PMCID:

PMC2702718

44. Chen GL and Miller GM. 5'-Untranslated Region of the Tryptophan hydroxylase-2 Gene

Harbors an Asymmetric Bidirectional Promoter but not Internal Ribosome Entry Site in vitro.

Gene 2009;435(1-2):53-62. PMCID: PMC2670360

45. Xie Z and Miller GM. A Receptor Mechanism for Methamphetamine Action in Dopamine

Transporter Regulation in Brain. Journal of Pharmacology and Experimental Therapeutics

2009;330(1):316-25. PMCID: PMC2700171

46. Ferguson B, Capitanio J, Folks T, Hotchkiss C, Johnson Z, Kean L, Kubisch HM, Lank S,

Lyons L, Miller GM, Nylander J, O'Connor D, Vallender EJ, Wiseman R. Resource brief: the

National Non-Human Primate DNA Bank. Methods. 2009;49(1):3-4. PMCID: PMC3172814

47. Kanthaswamy S, Capitanio JP, Dubay CJ, Ferguson B, Folks T, Ha JC, Hotchkiss CE,

Johnson ZP, Katze MG, Kean LS, Kubisch HM, Lank S, Lyons LA, Miller GM, Nylander J,

O’Connor DH, Palermo RE, Smith DG, Vallender EJ, Wiseman RW, Rogers J. Resources for

Genetic Management and Genomics Research on Non-Human Primates at the National Primate

Research Centers (NPRCs). Journal of Medical Primatology 2009;38 Suppl 1:17-23.

48. Xie Z and Miller GM. Trace amine-associated receptor 1 as a monoaminergic modulator in

brain. Biochemical Pharmacology 2009 78(9);1095-04. Review. PMCID: PMC2748138

49. Chen GL, Novak MA, Meyer JS, Kelly BJ, Vallender EJ, Miller GM. The Effect of Rearing

Experience and TPH2 Genotype on HPA Axis Function and Aggression in Rhesus Monkeys: a

Retrospective Analysis. Hormones and Behavior 2010;57(2):184-91. PMCID: PMC2815197

50. Vallender EJ, Ruedi-Bettschen D, Miller GM*, Platt DM. A pharmacogenetic model of

naltrexone-induced attenuation of alcohol consumption in rhesus monkeys. Drug and Alcohol

Dependence 2010;109(1-3):252-6. PMCID: PMC2875311 *Corresponding author

http://www.ncbi.nlm.nih.gov/pubmed/19706346?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

http://www.ncbi.nlm.nih.gov/pubmed/19706346?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Chen%20GL%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Novak%20MA%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Meyer%20JS%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Kelly%20BJ%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Vallender%20EJ%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Miller%20GM%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract

30

51. Vallender EJ, Xie Z, Westmoreland SV, Miller GM. Functional evolution of the trace amine

associated receptors in mammals and the loss of TAAR1 in dogs. BMC Evolutionary Biology

2010;10:51. PMCID: PMC2838891

52. Chen GL, Novak MA, Meyer JS, Kelly BJ, Vallender EJ, Miller GM. TPH2 5'- and 3'-

Regulatory Polymorphisms Are Differentially Associated with HPA Axis Function and Self-

Injurious Behavior in Rhesus Monkeys. Genes, Brain and Behavior 2010;9(3):335-347. PMCID:

PMC2990963

53. *Panas H, *Lynch L, Vallender E, Xie Z, Chen GL, Lynn S, Scanlan T and Miller GM.

Normal thermoregulatory responses to 3-iodothyronamine, trace amines and amphetamine-like

psychostimulants in trace amine associated receptor 1 knockout mice. Journal of Neuroscience

Research 2010;88(9):1962-9. PMC Journal - In Process *Shared first-authorship; both are Research Assistant III’s in my lab.

54. Miller GM. The Emerging Role of Trace Amine Associated Receptor 1 in the Functional

Regulation of Monoamine Transporters and Dopaminergic Activity. Journal of Neurochemistry

2011;116(2):164-76. PMCID: PMC3005101 Review, contains new data not published elsewhere.

55. Karmacharya R, Lynn SK, Demarco S, Ortiz A, Wang X, Lundy MY, Xie Z,

Cohen BM, Miller GM, Buttner EA. Behavioral effects of clozapine: Involvement of trace

amine pathways in C. elegans and M. musculus. Brain Research 2011, Jun 1;1393:91-9. PMCID:

PMC3107707

56. Westmoreland SV, Annamalai L, Lentz MR, Ratai EM, Assaf B, Boisvert K, Huynh T,

Vallender EJ, Miller GM, Madras BK, Gonzalez RG. Growth associated protein-43 and Ephrin

B3 Induction in the Brain of Adult SIV-infected Rhesus Macaques. Journal of Neurovirology.

2011. In press. PMC Journal - In Process

57. Lewin AH, Miller GM, Gilmour B. Trace amine-associated receptor 1 is a stereoselective

binding site for compounds in the amphetamine class. Bioorganic & Medicinal Chemistry Dec

1;19(23):7044-8, 2011. PMCID: PMC3236098

58. Achat-Mendes C, Lynch LJ, Sullivan KA, Vallender EJ, Miller GM. Augmentation of

methamphetamine-induced behaviors in transgenic mice lacking the trace amine-associated

receptor 1. Pharmacol Biochem Behav. Apr;101(2):201-207, 2012. PMCID: PMC3288391

59. Chen G-L and Miller GM. Advances in Tryptophan Hydroxylase-2 Gene Expression

Regulation: New Insights into Serotonin-Stress Interaction and Clinical Implications. American

Journal of Medical Genetics Part B: Neuropsychiatric Genetics. Mar;159B(2):152-171, 2012

PMC Journal - In Process

60. Miller GM. Avenues for the Development of Therapeutics That Target Trace Amine

Associated Receptor 1 (TAAR1). Journal of Medicinal Chemistry, Mar 8;55(5):1809-1814,

2012. PMCID: PMC3618978

61. Panas MW, Xie Z, Panas HN, Hoener MC, Vallender EJ, Miller GM. Trace Amine

Associated Receptor 1 Signaling in Activated Lymphocytes. Journal of Neuroimmune

Pharmacology Dec;7(4):866-76, 2012 PMC Journal - In Process

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Chen%20GL%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Novak%20MA%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Meyer%20JS%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Kelly%20BJ%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Vallender%20EJ%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Miller%20GM%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract

http://www.sciencedirect.com/science/journal/09680896




31

62. Chen GL, Miller GM. Tryptophan Hydroxylase-2: An Emerging Therapeutic Target for

Stress Disorders. Biochem Pharmacol. 2013 Feb 19 [Epub ahead of print], In press.

63. Chen GL, Miller GM. Extensive Alternative Splicing of the Repressor Element Silencing

Transcription Factor Linked to Cancer. PLOSOne 2013 Apr 16;8(4):e62217. PMCID:

PMC3628349

64. Lynch J*, Sullivan KA*, Vallender EJ, Rowlett JK, Platt DM, Miller GM. Trace Amine

Associated Receptor 1 Modulates Behavioral Effects of Ethanol. Substance Abuse: Research and

Treatment. 2013, Jun 4;7:117-126. PMC Journal - In Process * both are Research Assistant III’s in my lab.

65. Vallender EJ and Miller GM. Non-Human Primate Models in the Genomic Era: A Paradigm

Shift. Institute for Laboratory Animal Research Journal 2013 54: 154-165.

66. Dharmendra B Goswami DB, Ogawa LM, Ward JM, Miller GM, Vallender EJ. Large-scale

polymorphism discovery in macaque G-protein coupled receptors. BMC Genomics 2013,

14:703. PMC Journal - In Process

67. Cho JA, Zhang X, Miller GM, Lencer WI, Nery FC. 4-phenylbutyrate Attenuates the ER

Stress Response and Decreases Cyclic AMP Accumulation in DYT1 Dystonia Cell Models.

PLOSOne 2014, PONE-D-14-21412R1 in press.

Non-peer reviewed scientific or medical publications/materials in print or other media

1. Madras B, Miller GM, De La Garza R, Dougherty DD, Bonab AA, Spencer TJ, Rauch SL,

Fischman AJ. Brain Imaging of the dopamine transporter in ADHD. 6th

International World

Congress for Biomedical.Sciences 2000;113. PMC Journal - In Process

2. Gibson MJ, Saitoh Y, Miller GM, Silverman A-J. Functional GnRH neuronal transplants in

the hypogonadal mouse. In: Crowley WF Jr, Conn PM, editors. Modes of Action of GnRH and

GnRH analogs. New York, New York: Springer-Verlag, 1992:144-57.

3. Miller GM, Zhang X, Klibanski A. Pituitary tumors: future perspectives. In: Kovacs, K.

editors. Diagnosis and management of pituitary tumors. Totowa, New Jersey: Humana Press

Inc., 2001, pgs 462-6.

4. Miller GM and Madras BK. Genetic Variations and Phenotypic Associations Common to

Rhesus Monkeys and Humans. In: SA Wolfe-Coote, editor. The Laboratory Primate. Tygerberg,

South Africa: Medical Research Council of South Africa, Elsevier Publishing Inc., 2005.

5. Ferguson B, Miller GM. Genetic tools for understanding the primate genome. Methods

2009;49(1):1-2. Editorial.

Thesis

1. Miller GM. Neuromodulation of luteinizing hormone secretion in the mouse [dissertation].

New York (NY): City Univ. New York, 1993.



date prepared october 10, 2014 - northeastern universitydate prepared october 10, 2014 name gregory...

Documents