1CURRICULUM VITAE

Taura L. Barr PhD RN

Business Address: Assistant ProfessorDepartment of Health RestorationWest Virginia University School of Nursing& Emergency MedicineCenter for Neuroscience, Neural Injury GroupBiomedical Research BuildingOne Medical Center DriveOffice 119PO Box 9303Morgantown WV 26506Office: 304-293-0503tlbarr@hsc.wvu.edu

Adjunct Assistant ProfessorUniversity of Pittsburgh School of Nursing

BBG Sciences LLC. Chief Scientific Officer260 Allison StreetMorgantown, WV 26506

Home Address: 950 North Liberty Street TelephoneWaynesburg PA 15370 (724) 627-7989

Marital status: Married with 4 children

Dr. Barr is an Assistant Professor in the WVU School of Nursing and Emergency Medicine. She holds faculty appointments in the Center for Neuroscience, Basic and Translational Research in Stroke. Her training has spanned from basic preclinical models of neurological disease mechanism, to qualitative research methods to understand the human response to disease and the application of genetics and genomics in clinical research. Her program of research is centered on the use of genomic methodologies to identify biomarkers of neurological disease, understand their relationship with post-stroke inflammation and immunity, and define the contributing environmental factors related to health disparity in underserved populations.   http://www.hsc.wvu.edu/wvucn/Faculty---Lab-Personnel/Barr/Barr-Home

EDUCATION/TRAINING

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UNDERGRADUATE

4/2004 University of Pittsburgh BSN Nursing

GRADUATE

9/2004-12/2008 Graduate Partnership Program Intramural PredoctoralNational Institutes of Health Research Training Department of Health Fellow- NINR; NINDS,and Human Services NIA, TranslationalNational Institute of Nursing NeuroscienceResearch10 Center Drive: 10/1C129Bethesda, Maryland 20892http://gpp.nih.gov/*Relocation to the NIH campus September 2006

9/2004-4/2009 University of Pittsburgh BSN-PhD Defense April 20, 2009 Nursing Research,“Gene expression profiling TranslationalIn human acute ischemic stroke” Neuroscience

APPOINTMENTS AND POSITIONS

ACADEMIC RESEARCH

1/2001-4/2004 University of Pittsburgh Research AssistantSchool of Nursing NeurologyCenter for Nursing Research Critical CarePittsburgh, PAMary Kerr RN PhD FAAN

8/2004-1/2006 University of Pittsburgh Doctoral studentSchool of Medicine Research volunteerSafar center for ResuscitationResearchPittsburgh, PARobert S. Clark MDAssociate Director, Molecular Biology

10/2005-4/2006 University of Pittsburgh Doctoral StudentSchool of Nursing Research volunteerHealth Promotion & Development

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Pittsburgh, PAYvette P. Conley PhD

11/2005-5/2006 University of Pittsburgh Student Worker School of Nursing Health PromotionHealth and CommunityPittsburgh, PAEllen Olshansky DNSc, RNC, FAAN

2006 (June-July) Summer Genetics Institute FellowNational Institute of Nursing ResearchBethesda, MDFrancine Nichols RN PhD

8/2006-12/2008 National Institute of Intramural Neurological Disorders Predoctoraland Stroke ResearchStroke Diagnostics and Training Fellow,Therapeutics section of the Translational Stroke branch StrokeBethesda, MdSteven Warach MD PhD

1/2007-4/2009 National Institute of Aging Research Volunteer, Laboratory of Neurogenetics GPP Fellow,Bethesda, Md Translational Andrew Singleton PhD NeuroscienceMar Matarin PhD

6/2008-4/2009 National Institute of Research VolunteerNeurological Disorders and GPP FellowStroke Translational Clinical Investigations StrokeSection of the Stroke BranchBethesda, MdJohn Hallenbeck MDPaola Castri MD, PhD

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PROFESSIONAL/WORK EXPERIENCE

1/2001-3/2004 UPMC Presbyterian Hospital Nursing AssistantUnit 4FNeurovascular ICUPittsburgh, PA

2003 (May-August) UPMC Presbyterian Hospital Nurse InternUnit 10CIntermediate ICUPittsburgh, PA

4/2004-1/2005 UPMC Presbyterian Hospital Registered NurseUnit 4FNeurovascular/Neurotrauma ICUPittsburgh, PA

9/2006- 8/2008 Suburban Hospital Registered NursePost-Anesthesia Care Unit Clinician IIBethesda, MD

4/2008-1/2009 Progressive Nursing Staffers Registered NurseTraveler-ICU SpecialtyMaryland Hospitals

12/2008 -6/2010 Tissue Injury UnitNational Institute of Nurse Specialist Nursing Research (Research)Bethesda, MD GS-0610, Grade 12Raymond Dionne DDS PhD Step 01

7/2010-Present Department of Health Restoration Assistant Professor

West Virginia University School of Nursing,Center for Neuroscience, Neural Injury Group

5/2011-Present Dual Appointment Assistant ProfessorDepartment of Emergency Medicine

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West Virginia University

June 2012-Spring 2013 Scientific Advisory Committee ChairVuEssence Inc. Odessa, FL

November 2012-Present Mueller Law Offices ConsultantAustin, Tx

January 2013-Present University of Pittsburgh School of Nursing Adjunct Faculty

TEACHING EDUCATION/EXPERIENCE

6/2001 Certified phlebotomy training course offered by the Universityof Pittsburgh

1/2003-3/2004 Preceptor for all new-hire nursing assistantson Neurovascular/Neurotrauma ICUPittsburgh, Pa

1/2007-4/2008 Preceptor for new-hire registered nursesin Post-anesthesia care unitSuburban Hospital, Md

10/2007-3/2008 Introduction to the Principles and Practice of Clinical researchTraining ClassOffered by the NIH Clinical Research Center

4/2008 Workshop: Scientific writing and manuscript developmentOffered by the Office of Intramural Training and Education on the NIH campus

1/2008 Workshop: Scientists teaching science- An introduction to best practices in science educationOffered by the Office of Intramural Training and Education on the NIH campus

2/2008 Leadership Skills Workshop Offered by the Office of Intramural Training and Education on the NIH campus

5/2009-8/2009 Summer Student MentorSarma Klimanis, Junior BSN Nursing Student

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Florida State UniversityProject: Protein profile of AKAP-7 in stroke patients With blood brain barrier disruption

September 2009-March 2010 Post-baccalaureate student MentorIndira Gowda BSN RN

July 2010-present Post-doctoral student MentorReyna VanGildner PhD

September 2010-May 2011 First Grade CCD instructorSt. Ann’s Catholic ChurchWaynesburg, PA

October 28, 2010 Inflammatory Profile for Stroke Diagnosis: Information for NursesCE Seminar

January-May 2011 Neuroscience Graduate Student Rotation MentorPaula Webster

June 2011-August 2011 Medical Student Summer Research MentorSarah Ellison

June 2011-August 2013 Undergraduate Nursing Student Research MentorNoelle Lucke-Wold

July 2011-April 2013 Post-Doctoral student mentorStephanie Rellick

August 2011-September 2013 Neurosurgery Resident Research rotation mentorBrian Young MD

September 2011-Present Adjunct AppointmentUniversity of PittsburghSchool of Nursing

October-November 2011 Medical Student Research Rotation MentorChristopher C. Spears

May-August 2012 Kyle Stinehart, 2nd year Medical StudentSummer Research mentor

Summer 2012, 2013 WVU Summer Undergraduate Research Program Mentor

Spring 2012-Present WVU Teaching Scholars Program

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Spring 2013-Present Mentor, Research Training Program in the Behavioral & Biomedical Sciences (BBS), WVUDanielle Doll Training Fellow

CLASSES TAUGHT

November 2011 Guest LecturerNURS: PhD course, Measurement in Nursing, Physiologic measures

Spring 2011; Spring 2012 Neuroscience PhD Journal Club, Co-Course Coordinator NBAN 793, 1cr

Summer 2011; Fall 2011 Nursing Independent study NUR495, Course Coordinator, 1-3crSpring 2012; Summer 2012 Fall semester 2011 Noelle Lucke-Wold Undergraduate Nursing

Fall 2012 Fall semester 2012 Kate McCarthy Undergraduate Nursing

June 2011, 2012 Guest LecturerNUR 727 Health Assessment and CommunicationThe Translation of Genomic Methodologies to Human Ischemic Stroke

January-May 2011 Guest Lecturer2012, 2013 BMS 740: Neurobiology II Elective Module

Fall 2012 NUR 493R/488: Special topics Genetics and Genomics in Health and Disease, Course Coordinator, 2cr

Spring 2012 NUR 627: Research and Systematic Analysis, Co-instructor, 5cr

Spring 2012, 2013 PUBH 691 Academic Associates 3crLecturer

Spring 2013 NUR 704 Health Care Leadership 3crCo-Course Coordinator

CLASSES DEVELOPED, YET TO BE OFFERED

Spring 2014 Graduate Level Course: Stroke: From Bench to Bedside to Community 2crCo-Course Coordinator

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Fall 2014 Incorporating Genetics/Genomics into Nursing CurriculumOnline course for WVU nursing faculty/ instructorsCourse Coordinator, Continuing Education Credits

DISSERTATION COMMITEES SERVED ON

2011-2012 Amy Prostko PhD Neuroscience

2010-2013 Ryan Turner MD/PhD Neuroscience

2011-Presesnt Alisa Elliott PhD Neuroscience

2012-Present Daniell Doll PhD NeuroscienceCommittee Chair 2012-2013

2012-Present Steve Brooks PhD Cellular and Integrative PhysiologyCommittee Chair 2012-2013

2013-Present Sara Fournier PhD Exercise Physiology

2013-Present Jiahong Sun PhD Neuroscience

UNDERGRADUATE HONORS COMMITTEES SERVED ON

January 2013-Present Frank (Tony) Lacy BS Biology StudentPrimary Mentor January-August 2013

INVITED LECTURES

9/2007 NINR Council“Gene Expression Profiling of Complex Diseases”Bethesda, Md

6/2008 Summer Genetics InstituteLecture, Genetics/GenomicsNational Institute of Nursing ResearchBethesda Md

8/2008 Stroke Team Grand RoundsNational Institutes of Health“Gene Expression Profiling and Biomarker Discovery in Ischemic Stroke”Suburban Hospital Bethesda Md

9/2009 Summer Genetics Institute

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Lecture “Gene expression profiling and advances in

methodologies”National Institute of Nursing ResearchBethesda MD

11/2009 NINR Research Festival“Genomic approaches for the characterization of neurological

disease”Graduate Partnerships Program, National Institute of Nursing ResearchBethesda MD

11/2010 NIH Clinical Center Grand Rounds“An Inflammatory Profile for Stroke Diagnosis and Outcome Prediction”NIH Clinical CenterBethesda MD

11/2010 WVU Neurology Grand RoundsAn inflammatory profile for stroke diagnosis and outcome predictionHealth Sciences CenterMorgantown, WV

3/2011 Ruby Memorial Hospital, Nursing Research Council Retreat“Role of the Nurse Scientist in Clinical Translational Stroke Research”Ruby Memorial HospitalMorgantown, WV

3/2011 WVU Emergency Medicine Grand Rounds“An inflammatory profile for stroke diagnosis and outcome prediction”Health Sciences CenterMorgantown, WV

5/2011 Annual Sigma Theta Tau ConferenceFeatured Speaker“Inflammatory and Immune Profiles of Ischemic Stroke”Health Sciences CenterMorgantown, WV

6/2011 NINR Summer Genetics Institute“Bedside to Bench and Back: Gene Expression Profiling for the Characterization of Human Neurological Disease” Bethesda, MD June 2011

6/2011 WVU Neuroscience Retreat 9

“Inflammatory and Immune Profiles of Ischemic Stroke: Bedside to Bench & Back”, Stonewall Jackson Resort

6/2011 CNRM Biomarkers Meeting “Characterization of the Human Blood Transcriptome Response to TBI: Study Update”, USUHS, Bethesda MD

11/2011 NHGRI Workshop “What Does It Mean to be Genomically Literate?”“West Virginia Community Genetics Forum”Rockville, MD

5/2012 NINR National Advisory Council, open session Scientific Presentation

“Mechanisms of Stroke Induced Immune Suppression”Bethesda, MD

6/2012 National Community Committee Genomics Webinar“West Virginia Community Genetics Forums”Web-based

7/2012 WV-INBRE Steering Committee Meeting“Monitoring Gene Expression to Predict Stroke Recovery”Morgantown, WV

8/2012 WVU Mary Babb Randolf Cancer Center Osborn retreat “CTLA4 signaling and Stroke Recovery”Morgantown, WV

11/2012 American Heart Association, Scientific Sessions“Genomics of Stroke and Translation into the Emergency

Department”Los Angeles, CA November 3-8, 2012

3/2013 WVU LIINC HSC Graduate Student DinnerDanielle Doll (Mentee)A Biolmarke Algorithm for Determing Time ofStroke Symptom Onset

6/2013 NINR Summer Genetics Institute“Gene Expression Profiling for the Characterization of Human Neurological Disease” Bethesda, MD June 2013Presented by Steven Brooks (Mentee)

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COMMUNITY PRESENTATIONS

8/2/2011 “Family Health History, Genes and the Environment”Mount Hope Youth CenterMount Hope, WV

12/1/2011 “Family Health History, Genes and the Environment”McDowell County Visitor and Veterans CenterKimball, WV

2/16/2012 “Family Health History, Genes and the Environment”Calhoun County Committee on AgingGrantsville, WV

7/19/2012 “Family Health Stories and Knowing Disease Risk”Calhoun County Committee on AgingGrantsville, WV

INVITED MEETINGS

September 2010 First Annual GenoCommunity Think TankWVU RepresentativeSt. Louis, MO

November 2011 National Human Genome Research Institute (NHGRI) workshop “What Does It Mean to be Genomically Literate?”Rockville, MD November 17-18, 2011.

April 2012 Personal Genetics Education Project and the 2012 Genomes Environments Traits (GET) ConferenceApril 24-25, 2012Harvard Medical SchoolBoston, MA

April 2013 Personal Genetics Education Project (pgEd) - and the 2013 Genomes Environments Traits (GET) Conference

INVITED MEMBERSHIPS

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September 2010-August 2013 Affiliated FacultyWVU Injury Control Research Center (ICRC)

March 2011-Present Affiliated Faculty, WVU Prevention Research Center (PRC)

June 2012-present Affiliated FacultyWVU Center for Cardiovascular and Respiratory Sciences

LICENSURE/CERTIFICATIONS

2004 (August)-Present Pennsylvania RN License #RN557830

2000-Present Basic CPR

2006 (September)-2012 Maryland RN License #R175589

2006-2011 Advanced Cardiac Life Support

2007-Present NIH Stroke Scale Certification

2010 (September)-Present West Virginia RN License #79595

CE CREDITS

October 22, 2010 Building Knowledge for NursingWVU Healthcare and Sigma Theta Tau7.9 contact hours

September 9, 2010 Using Theory to Create an Innovative Learning ExperienceRoger Carpenter PhD RN1 contact hour

3/2011 Ruby Memorial Hospital, Nursing Research Council Retreat“Role of the Nurse Scientist in Clinical Translational Stroke Research”Ruby Memorial HospitalMorgantown, WV

5/2011 Annual Sigma Theta Tau ConferenceFeatured Speaker“Inflammatory and Immune Profiles of Ischemic Stroke”Health Sciences CenterMorgantown, WV8 credits

5/2011 WVU Hospitals“An inflammatory profile for stroke diagnosis and outcome

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prediction”1 contact hour

5/2011 WVU Healthcare Stroke ConferenceFlatwoods, WV 6 contact hours

11/2012 Annual Sigma Theta Tau ConferenceFeatured Speaker“West Virginia Community Genetics Project”Health Sciences CenterMorgantown, WV8.2 credits

GRANT FUNDING & COLLABORATIVE RESEARCH

Completed

2005 Grant submission titled “Assessment of Poly (ADP-ribose) polymerase -1 activity via poly(adp-ribose) expression in cerebrospinal fluid after severe traumatic brain injury in adults”, Application to Norma J. Shoemaker Grant 2006, Society of Critical Care Medicine (unfunded); received internal funding through the Safar Center for Resuscitation Research, Pittsburgh PA

2006 “Gene expression profiling of human acute ischemic stroke”; Internal funding National Institute of Neurological Disorders and Stroke; National Institute on Aging

2008 “KCNK17 Polymorphisms in acute ischemic stroke”; internal funding National Institute on Aging

2009 “Characterization of the human blood genomic response to traumatic brain injury”. Center for Neuroscience and Regenerative Medicine (Department of Defense and Uniform Services University) Sub-project proposal grant; Co-PI: Taura Barr PhD RN $250,000 for 2 years, June 1, 2009. Madigan Army Medical Center IRB #145947-1

2010 “Combined approach to lysis utilizing Eptifibatide (Integrillin) and rt-PA (Activase, Altiplase, recombinant) in Acute Ischemic Stroke-Enhanced Regimen (CLEAR-ER Stroke Trial)” H-22009 PI: Todd Crocco MD, Emergency Medicine WVU; Co-investigator: T. Barr

2010 “Evaluating the functional role of A-kinase anchor protein 7 (AKAP7) in blood brain barrier disruption following stroke” Supplement to RO1 NS061954; PI: Jason Huber PhD Basic Pharmaceutical Sciences, WVU; Co-PI: Taura Barr PhD RN; $73,500

2011 “Genomic Expression of Chronically Ill Lonely Older Adults” WVU School of Nursing Pilot Funding. PI: Laurie Theeke, Co-Investigator: T. Barr The objective of this project is

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to describe the relationship between serum cytokines with gene expression of select inflammatory makers in chronically ill lonely older adults. $6,000 Protocol #H22191, WVU IRB.

2011 “Quality of Life in Stroke Survivors Living in Appalachia” WVU School of Nursing Pilot Funding. PI: Patricia Horstman MSN, Co-Investigator: T. Barr The objective of this project is to describe the experience of surviving stroke for adults living in Appalachia. $1,000. Protocol #H23361

2011 West Virginia Community Genetics Forum. NHGRI Intramural Contract. PI: Taura Barr Our proposed Community Genetics Forums will establish a model of community engagement centered on the importance of family health history and understanding individual risk for disease to educate and empower WV communities at large. $21,500. Protocol #H23358, WVU IRB.

2011 “Phospho-kinase Screening to Characterize Biomarkers of Ischemic Stroke”. WVU Internal Senate Grant Application, PI: Taura Barr, The objective of this study is to identify functional mediators of immune pathway signal transduction in the aged rat brain. $10,200

2011 “Monitoring gene expression post-stroke to predict stroke outcome”. Marshall University Genomic Core, INBRE and ACORN network PI: Taura Barr The objective of this study is to examine the relationship between the change in the peripheral blood gene expression over time and ischemic stroke outcome. $24,500

2011 “Gene Expression Profiling for Outcome Prediction following Mild Traumatic Brain Injury”. WVU Internal Clinical Genomics Discovery Grant, PI: Taura Barr, The purpose of this project is to elucidate the genomic mechanisms of clinical variability in human mTBI through the use of gene expression profiling of peripheral whole blood. $5,000

2011 “Validation of a Gene Expression Profile of Ischemic Stroke”. NIH Intramural Contract. PI: Taura Barr. The objective of this contract is to extend and commercialize a nine gene profile for ischemic stroke diagnosis. $67,340 Protocol #H22566, WVU IRB.

2011 “West Virginia Prevention Research Center” US DHHS/CDC PI: Geri Dino, CO Investigator: T. Barr $615,000 ($6,171 salary support for T. Barr )

2012 The West Virginia Community Genetics Family Health History Awareness Project; National Human genome Research Institute PI: Taura Barr, $99,000, 9/24/2012-9/23/2013 research and support at 5%

In Progress2011 NIH RO1 NS 061954 Supplement; Collaborative Activities to Promote Translational

Research (CAPTR) program 8/2/2010-3/31/2013, Evaluating the functional role of A-kinase anchor protein 7 (AKAP7) in blood-brain barrier disruption following Stroke, $60,500 PI: Jason Huber, PhD West Virginia University, Basic Pharmaceutical Sciences Co-Investigator: Taura Barr

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2012 “A GPS (Genomic Profile of Ischemic Stroke) for Stroke Recovery” Robert Wood Johnson, Nurse Faculty Scholars Program. PI: T. Barr $300,000 September 2012-August 2015 60% salary support

2012 “WV IDeA Clinical Translational Research”. PI: Uma Sundaram MD, Role: Research Scholar Taura Barr 10% salary support

Submitted Not Funded in 2013

2013 NIH NRSA Predoctoral Fellowship Application, Steven Brooks (Mentee).

2013 West Virginia Stroke COBRE Application; National Institutes of Health. Sub-Project PI: Taura Barr, $250,000; January 2013-December 2018.

2013 NIH Innovator Award application, The Effectiveness of thet LISTEN intervention on Loneliness, Biophysical measures of chronic illness and facial expression, PI: Laurie Theeke; Co-investigator Taura Barr

Submitted Under Review

NIH R13, West Virginia Stroke Immune System Interaction Conference (PI JWS), $30,000 requested

Grants in Preparation

West Virginia Stroke COBRE Application Resubmission; National Institutes of Health. Sub-Project PI: Taura Barr, $250,000; June 2014-May-2019.

PA-13-264 Synergizing Omic and Symptom Science (RO1), A Genomic Biosignature of Post-Stroke Immune Dysfunction, PI Taura Barr

PUBLICATIONS*Denotes mentee and/or Corresponding author

Book Chapters1. Barr, T.*, Sacco, D., Olshansky, E. Sexually Transmitted Diseases In Medical Surgical

Nursing: A pathophysiologic approach. Lippincott Williams, Philadelphia PA 20072. Van der Brug, M; Matarin, M; Barr, T*; Characterization of RNA in Biochemical and

Molecular Biological Assessments IN Animal Models of Acute Neurological Injuries II; Editor Chen, J.; Xu, X.-M.; Xu, Z.C.; Zhang, J.H. (Eds.) 2012, 700 p. 171 illus., 119 in color.

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3. VanGilder, R., Huber, J., Barr, T*; Brain Gene Expression in Stroke, IN Transcriptome Analysis of Multifactorial Diseases Affecting the CNS; Editor Matarin, M.

Book Chapters in Press1. Brooks, S.; VanGilder, R; Barr, T*. “Genomics for the Advancement of Clinical

Translation in Stroke” Special edition, Rational basis for clinical translation in stroke therapy in Frontiers in Neurotherapeutics

Manuscripts 1. Barr, T.*, Conley, Y. Poly (adp-polymerase)-1 and brain injury: Implications for nursing practice. J Neurosci Nurs . 2007 Oct;39(5):278-84. (4 Citations, Google Scholar)

2. Barr T, Alexander, S., Crago, B., Horowitz, M., Yonas, H., Kerr, M. The Impact of Endovascular Coiling Versus Surgical Clipping on Functional Outcome After Intracranial Aneurysm Rupture. 2008 March; Neurosurgery Quarterly 18 (1):16-21. (6 Citations, Google Scholar)

3. Barr T*, Latour LL, Lee KY, Schaewe T, Luby M, Chang G, El-Zammar Z, Alam S, Kidwell C, Warach S. Blood–Brain Barrier Disruption in Humans Is Independently Associated With Increased Matrix Metalloproteinase-9. 2010 Stroke 41(3):e123-e128. (28 Citations, Google Scholar)

4. Sarnik, A; Conley, Y; Okonkwo, D; Barr, T; Fink, E; Szabo, C; Kochanek, P; Clark, R. Influence of PARP-1 Polymorphisms in Patients after Traumatic Brain Injury. 2010 Journal of Neurotrauma 27:1-7 (9 Citations, Google Scholar)

5. Barr T*, Alexander S, Conley Y. Gene Expression Profiling for Discovery of Novel Targets in Human Traumatic Brain Injury. Biological Research in Nursing 2011 Apr;13(2):140-53 (2 Citations, Google Scholar)

6. Barr, T*; Conley, Y; Dillman, A; Ding, J; Warach, S; Singleton, A; Matarin, M; Genomic biomarkers and cellular pathways of ischemic stroke by RNA gene expression profiling. Neurology 2010; 75:1–1 (5 Citations, Google Scholar)

7. Kwako, L; Glass, N; Campbell, J; Melvin, K; Barr, T; Gill, J; Traumatic Brain Injury in Intimate Partner Violence: A Critical Review of Outcomes and Mechanisms. Trauma, Violence and Abuse July 2011 vol. 12 no. 3 115-126 (2 Citations, Google Scholar)

8. VanGilder, R (mentee); Rosen, C.; Barr, T.; Huber, J. Targeting the neurovascular unit for treatment of neurological disorders. Pharmacology and Therapeutics 2011 Jun;130(3):239-47 (9 Citations, Google Scholar)

9. Horstman, P; Theeke, L.; Culp, S.; Barr, T.; Gutmann, L; Domico, J; Lucke-Wold, A; Quality of Life and Loneliness in Stroke Survivors Living in Appalachia. Journal of Neuroscience Nursing, in Press.

10. VanGilder, R. (Mentee); Davidov, D.; Stinehart, K.; Huber, J; Turner, R; Wilson, K; Haney, E; Davis, S; Chantler, P; Theeke, L; Rosen, C; Crocco, T; Gutmann, L; Barr, T*. Systematic

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Review of Hs-CRP and Long-term Ischemic Stroke Prognosis, Journal of Clinical Neuroscience, Accepted.

11. Vincent Mysliwiec, MD1; Jessica Gill, PhD2; Hyunhwa Lee, PhD2, Tristin Baxter, AAS1; Roslyn Pierce, BS1; Taura Barr, PhD3, Barry Krakow MD, Bernard Roth MD. Sleep Disorders in US Military Personnel: A High Rate of Comorbid Insomnia and Obstructive Sleep Apnea, CHEST, 2013 144(2):549-57.

12. Brooks, S (Mentee); Spears, C; Cummings, C; VanGilder, R; Stinehart, K; Gutmann, L; Domico, J; Culp, S; Carpenter, J; Rai, A; Barr, T*. The Neutrophil-Lymphocyte Count Ratio predicts Outcome in Acute Ischemic Stroke Patients undergoing Endovascular Therapy, Journal of Neurointerventional Surgery Accepted.

13. Barr, T*; VanGilder, R.; Rellick, S.; Doll, D.; Brooks, S.; Chen, D.; Denvir, J.; Warach, S.; Singleton, A.; Matarin, M. A genomic profile of the immune response to stroke with implications for stroke recovery. Circulation, in revision

14. Lee, H.; Barr, T; Gill, J; Kim, H; Advancing Nursing Research with Genomic Approaches. Nursing Research, in revision.

15. Gill, J.; Lee, H.; Barr, T.; Baxter, T.; Heinz, M.; Rak, H.; Mysliwiec, V. Health Related Quality of Life Declines in U.S. Military Personnel are Associated with Service-Related Disorders and Inflammation. Psychosomatic Medicine, Under Review.

16. T. Barr1* J. Huber1, R.Turner1, R.VanGilder1, J.Ding2, C.L. Rosen1, M.Matarin3; A. Singleton2; S. Warach4. A-kinase anchor protein 7 (AKAP7) associated Blood Brain Barrier Disruption following Ischemic Stroke. Science Translational Medicine, in revision

17. Lee, H; Cabrejos, A; Barr, T; Gahlaez, I; Baxter, T; Heinzelmann, M; Mysliwiec, V; Gill, J Symptom Cluster Profiles of PTSD, Depression, Post-concussive syndrome and Sleep Disturbance in US Military Personnel who were Deployed. Sleep, Under Review

Manuscripts in Preparation

18. Barr, T*; VanGilder, R; Chantler, P; Huang, S. Toll like receptor and T cell signaling in Stroke and Atherosclerosis. Cardiovascular Genetics.

19. Barr, T*; Mallow, J; Theeke, L; Crawford, P; Prendergast, E; Conner, C; Richards, T; Reed, D; Stabler, M; Luo, J; Dino, G. Family Health Stories and Epigenetics in Rural Appalachia: The West Virginia Community Genetics Forums. Genome Medicine 20. Barr, T*; Mallow, J; Theeke, L; Crawford, P; Prendergast, E; Conner, C; Richards, T; Reed, D; Stabler, M; Luo, J; Dino, G. Genomic Knowledge in Rural Appalachia: The West Virginia Genome Community Project. The American Journal of Nursing

21. Barr, T*; Mallow, J; Theeke, L; Crawford, P; Prendergast, E; Conner, C; Richards, T; Reed, D; Stabler, M; Luo, J; Dino, G. A Method of Engagin rural Appalachian communities in genetics education and family health history awareness: The West Virginia Genome Community Project. Journal of Medicial Genetics.

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22. Theeke, L. Barr, T; Rellick, S; VanGilder, R; McBurney, A; Lucke-Wold A. Genomic Expression of Chronically ill lonely older adults. Biological Research in Nursing

23. Theeke, L; Barr, T; Mallow, J; Horstman, P; Lucke-Wold, A. Stepping Forward: Life after Stroke in Appalachia. International Journal of Stroke.

24. Reed, M; Doll, D; Simpkins, J; Barr, T*. Aging and Stroke: The Human Condition. Book Chapter

25. VanGilder, R (mentee); Turner, R; Monseau, A; Minardi, J; Gurka, K; Davidov, D; Davis, S; Barr, T; Coben, J. Visits to United States Emergency Departments for Post-Concussive Syndrome. Journal of Emergency Medicine.

Community Publications

1. Documenting Family health history, preventing chronic health problems. Hur Herald: Calhoun county West Virginia News, March 9, 2013

POSTER PRESENTATIONS

1. Palfreyman, T., Beatty, M. (2004). Comparison of coiling versus clipping on sixmonth outcomes following subarachnoid hemorrhage. SCCM Society of Critical Care Medicine. Orlando, Fl., February 2004.

2. Palfreyman, T., Beatty, M. (2004). Comparison of coiling versus clipping on sixmonth outcomes following subarachnoid hemorrhage. Eastern Nursing Research Society. Boston, Ma, March 2004.

3. Barr, T., Conley, Y., Latour, L., Singleton, A., Warach, S. (2007) Blood Brain Barrier Disruption and Gene Expression Following Acute Ischemic Stroke in Humans. Graduate Partnership Program Research Festival. Bethesda, Md, May 2007.

4. Barr T, Matarin M, Ding J, Conley Y, Warach S, Singleton S. (2008) Genetic mechanisms of acute ischemic stroke. NINR Summer Genetics Institute. Bethesda Md, June 2008.

5. Barr, T; Latour, L; Kidwell, C; Lee, K; Merino, J; Warach, S. (2009) Age is the major risk factor of early blood brain barrier disruption in acute ischemic stroke. American Heart Association International Stroke Conference in San Diego February 2009.

6. Barr, T; Nalls, M; Singleton, A; Arepalli, S; Rich, S; Hardy, J; Meschia, J; Matarin, M. (2009) Polymorphisms in KCNK17 are not associated with ischemic stroke. Eastern Nursing Research Society, Boston, Ma, March 2009.

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7. Barr, T; Matarin, M; Ding, J; Conley, Y; Warach, S; Singleton, A. (2009) In search of a gene expression profile for acute ischemic stroke. Eastern Nursing Research Society, Boston, Ma, March 2009.

8. Klimanis, S (Mentee); Castri, P; Barr, T. (2009) AKAP7: A novel candidate for blood brain barrier disruption. NIH Summer Student Research Festival, Bethesda Md, August 2009.

9. Barr, T; Conley, Y; Dillman, A; Ding, J; Warach, S; Singleton, A; Matarin, M; In search of a gene expression profile for acute ischemic stroke. GPP Research Festival, Bethesda Md, November 2009

10. Barr, T; Conley, Y; Dillman, A; Ding, J; Warach, S; Singleton, A; Matarin, M; Inflammatory regulation as a biomarker of ischemic stroke diagnosis: evidence from gene expression profiling. AHA International Stroke Conference 2010, San Antonio Texas February 23-25.

11. Barr, T; Conley, Y; Dillman, A; Ding, J; Warach, S; Singleton, A; Matarin, M; Inflammatory regulation as a biomarker of ischemic stroke diagnosis: evidence from gene expression profiling. NIH, NCRR Third Biennial National IDeA Symposium of Biomedical Research Excellence (NISBRE) 2010, Bethesda MD, June 16-18.

12. Barr, T; Conley, Y; Dillman, A; Ding, J; Warach, S; Singleton, A; Matarin, M; Gene expression profiling for ischemic stroke diagnosis. The Center for the Advancement of Nursing Science Conference, 2010, Washington DC, September 27-29.

13. Barr, T; Conley, Y; Dillman, A; Ding, J; Warach, S; Singleton, A; Matarin, M; Gene expression profiling for ischemic stroke diagnosis. NINR’s 25th Anniversary Scientific Symposium: Bringing Science to Life, 2010, Bethesda MD, September 30

14. Barr, T; Reyna VanGilder; Alexa Richie; Jason Huber; Dongquan Chen; Steve Davis; Laurie Gutmann; Todd Crocco; Jeffrey Coben; Charles Rosen; James Meschia. Validation of a Gene Expression Profile for Ischemic Stroke and Outcome Prediction. United States Critical Illness and Injury Trials Group (USCIITG) Annual Fall Meeting, 2010, Bethesda MD, November 9-10

15. VanGilder R (Mentee); Warach, S; Chen D; Denvir, J; Singleton A; Matarin, M; Barr, T. Immune Suppression post Ischemic Stroke may be Regulated by TLR4 and CTLA4 signaling. Van Leire Research Day, 2010, WVU Health Sciences Center, March 10 2011.

16. Sarah Ellison (Mentee), Stephanie L. Rellick, Ph.D, Reyna VanGilder, Ph.D., Taura L. Barr, RN, Ph.D. Gene Expression: A Potential Clinical Diagnostic for Ischemic Stroke Summer Student Seminar WVU Health Sciences Center, March 10 2012.

17. Christopher Chauncey Spears (Mentee); Christopher Cummings; Laurie Gutmann; Jennifer Domico; Stacey Culp; Jeffrey Carpenter; Ansaar Rai; Taura L. Barr. The Neutrophil-Lymphocyte Count Ratio as a Predictor of Ischemic Stroke Prognosis. Van Leire Research Day, 2012, WVU Health Sciences Center, March 2012.

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18. Sarah Ellison (Mentee), Stephanie L. Rellick, Reyna VanGilder, James Denvir, Todd Crocco, Laurie Gutmann, Taura L. Barr. A Genomic Profile of Stroke Recovery. Van Leire Research Day, 2012, WVU Health Sciences Center, March 2012.

19. Noelle Lucke-Wold (Mentee), Stephanie L. Rellick, Reyna VanGilder, Jason Huber, Brian Yung, Charles Rosen, Taura L. Barr. MMP-9 as a Peripheral Marker of Brain Injury. 2nd Place Student Poster, Van Leire Research Day, 2012, WVU Health Sciences Center, March 2012.

20. VanGilder RL (mentee), Turner R, Rellick SL, Barr TL, Rosen CL, Huber JD. The Effects of Lipopolysaccarhide Preconditioning on a Diffuse Axonal Injury. TBI National Capital Area TBI Research Symposium, Bethesda MD, May 22 2012.

21. Brooks (Mentee) , Doll , Rellick, VanGilder; Huber, Rosen, Cantor, Sallam, Barr. A Gene Profile for Predicting Time of Stroke Onset. WVU Center for Neuroscience Retreat, Snowshoe Resort WV, July 27-28, 2012.

22. VanGilder (Mentee), Rellick, James Denvir, Todd Crocco, Laurie Gutmann, Barr. A Genomic Profile of Stroke Recovery. WVU Center for Neuroscience Retreat, Snowshoe Resort WV, July 27-28, 2012.

23. Stinehart (mentee); Spears; Cummings; Gutmann; Domico; Culp; Carpenter; Rai; Barr. The Neutrophil-Lymphocyte Count Ratio as a Predictor of Ischemic Stroke Prognosis. WVU Center for Neuroscience Retreat, Snowshoe Resort WV, July 27-28, 2012.

24. Lucke-Wold (mentee), Rellick, VanGilder, Huber, Yung, Rosen, Barr. MMP-9 as a Peripheral Marker of Brain Injury. WVU Center for Neuroscience Retreat, Snowshoe Resort WV, July 27-28, 2012.

25. Lucke-Wold (mentee), Rellick, VanGilder, Huber, Yung, Rosen, Barr. MMP-9 as a Peripheral Marker of Brain Injury. The Council for the Advancement of Nursing Science National Meeting, Washington DC September 13-15, 2012.

26. Invitation to Present Poster at West Virginia University's Linking Innovation, Industry and Commercialization (LIINC) event. Barr, T. Genomic Biomarkers of Stroke and Cardiovascular Disease. January 2013

27. Steven D Brooks (Mentee); Kyle Stinehart; Stephanie Rellick; Danielle Doll; Reyna VanGilder; Taura Barr. Arginase-1 and S100a12 are Novel Candidates for the Study of Post Stroke Immune Suppression. AHA International Stroke Conference, Honolulu HI February 2013.

28. Reyna VanGilder (Mentee); Stephanie Rellick; Jason Huber; Charles Rosen; Ryan Turner; Taura Barr. An Association Between Tlr And Jak Signaling Following Cerebral Ischemia: A Translational Approach. AHA International Stroke Conference, Honolulu HI February 2013.

29. Danielle N Doll1 (Mentee); Steven D Brooks1; Stephanie L Rellick1; Reyna L VanGilder1; Alan Cantor2; Maha Sallam3; Taura L Barr1. A Biomarker Algorithm that

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Represents Time from Stroke Symptom Onset. AHA International Stroke Conference, Honolulu HI February 2013.

30. Taura L Barr1; Reyna VanGilder1; Stephanie Rellick1; Steven Brooks1; Danielle Doll1; Ann Noelle Lucke-Wold1; Dongquan Chen2; James Denvir3; Steven J Warach4; Andrew B Singleton5; Mar Matarin6. A Genomic Profile of Immune Mediated Mechanisms Associated with Stroke Recovery. AHA International Stroke Conference, Honolulu HI February 2013.

31. Vincent Mysliwiec, MD, FCCP; Jessica Gill, PhD; Hyunhwa Lee, PhD; Tristin Baxter, AAS; Morgan Heinzelmann, PhD; Taura L. Barr, PhD; Bernard J. Roth, MD, FCCP. Prospective Observational Study of Military Personnel with Obstructive Sleep Apnea: Changes in Symptoms of Service Related Illnesses and IGF-1 Expression. CHEST Conference October 2013

32. Everett Nixon, Stephanie Rellick, Taura Barr and James Simpkins, Assessment of the mitochondrial function in human lymphocytes, Van Liere Poster, March 1, 2013.

33. Stephanie L. Rellick, Debbie Piktel, Taura L. Barr, James W. Simpkins and Laura F. Gibson, The bone marrow microenvironment induces a dormant phenotype in leukemic cells, Van Liere Poster, March 1, 2013.

34. Brooks, S (Mentee); Stinehart; Spears; Cummings; Gutmann; Domico; Culp; Carpenter; Rai; Barr*. A Neutrophil-lymphocyte ratio cut-point predicts poor outcome after endovascular stroke therapy. (First place poster award) WVU Stroke Conference April 2013.

34. DN Doll, SL Rellick, TL Barr, JW Simpkins, Neuronal mitochondrial function and neuronal cell viability are affected by pro-inflammatory and anti-inflammatory cytokines. 2013 Neuroscience Retreat, Stonewall Report, WV, June 23-24, 2013. (Second Place-Graduate Student Division)

35. VanGilder, R (mentee); Chantler, P.; Huang, S.; Barr, T. Analysis of a Genomic Immune Profile in Stroke and Atherosclerosis. Neuroscience Retreat, Stonewall Report, WV, June 23-24, 2013.

36. Doll, D; Rellick, S; Barr, T; Simpkins, J. Neuronal mitochondrial function and neuronal cell viability are affected by pro-inflammatory cytokines. Society for Neuroscience November 2013 San Diego Ca.

36. Barr, T.; Lucke-Wold, N.; Mallow, J.; Horstman, P. Theeke, L. Life After Stroke in Appalachia. Southern Nursing Research Society Annual Meeting. February 2014,

37. Theeke, L.; Barr, T.; Rellick, S.; Mallow, J. Genomic Expression Changes of Chronically Ill Lonely Older Aduts who Participated in the LISTEN intervention trial. Southern Nursing Research Society Annual Meeting. February 2014, Submitted.

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ORAL RESEARCH PRESFENTATIONS1. Barr, T., Lai, Y., Alexander, S., Conley, Y., Clark, R.S. (2006) Poly (adp-ribose)

quantification in an adult traumatic brain injury population. The International Society of

Nurses in Genetics conference in New Orleans October 2006

2. Barr, T., Lai, Y., Alexander, S., Conley, Y., Clark, R.S. (2006) Poly (adp-ribose) quantification in an adult traumatic brain injury population. The Center for the Advancement of Nursing Science Conference in Washington DC October 2006.

3. Barr, T., Latour, L., Lee, K., Schaewe, T., Luby, M., Chang, G., El-Zammar, Z., Alam, S., Kidwell, C.,

Warach, S. (2008) MMP-9 and Blood brain barrier disruption in humans. American Heart Association International Stroke Conference in New Orleans February 2008.

4. Barr, T., Latour, L., Lee, K., Schaewe, T., Luby, M., Chang, G., El-Zammar, Z., Alam, S., Kidwell, C.,

Warach, S. (2008) MMP-9 and Blood brain barrier disruption in humans. The Center for the Advancement of Nursing Science Conference in Washington DC October 2008.

5. VanGilder, R. (mentee), Warach, S., Chen, D., Singleton, A., Matarin, M., Barr, T. (2010) Inflammatory Regulation through TLR Signaling may play a role in Ischemic Stroke Outcome. Sigma Theta Tau Research Conference, Morgantown WV, October, 2010.

6. Barr, T. "Genomic Characterization of Ischemic Stroke and Clinical Translation" WVU Stroke Conference, Flatwoods WV May 2011

7. Barr, T. "Monitoring Gene Expression Post-Ischemic Stroke to Predict Outcome" ACoRN/INBRE Conference Marshall University, Huntington WV July 2011

8. Barr, T, Crawford, P. (2011) “West Virginia Community Genetics Forum”. What does it mean to be Genomically literate, Rockville MD November 2011.

9. Lee, H., Wang D., Pierce R., Baxter T., Dionne R., Kim H., Mysliwiec V., Barr, T. Gene expression profiling in mild traumatic brain injury, post-traumatic stress disorder and their comorbid condition among post-deployed military service members. Amer Soc Neurochem, Baltimore 2012

10. Barr, T. Family Health History and Epigenetics in Rural Appalachian Communities: The West Virginia Community Genetics Forum. Appalachian Health Summit, Lexington Ky March 29, 2012.

11. Doll, D. (Mentee) A Gene Profile for Predicting Time of Stroke Onset. SIGMA THETA TAU ALPHA RHO CHAPTER RESEARCH CONFERENCE ADVANCING INTERPROFESSIONAL HEALTH RESEARCH, Morgantown WV November 1, 2012

12. Barr, T. Family Health Stories as a Tool to Educate Communities about Genomics and Individual Risk for Disease SIGMA THETA TAU ALPHA RHO CHAPTER RESEARCH

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CONFERENCE ADVANCING INTERPROFESSIONAL HEALTH RESEARCH, Morgantown WV November 1, 2012

PATENTS

1. WIPO Patent Application WO/2011/106322 Biomarkers for Acute Ischemic Stroke

2. Submitted Invention Disclosure with West Virginia University, A Biomarker Algorithm for Determining the Time of Stroke Symptom Onset February 2013.

3. Submitted Employee Invention Report with the National Insitute of Neurological Disorders and Stroke, A kinase anchor protein 7 (AKAP7) and blood brain barrier disruption March 2013

HONORS/AWARDS

2001 Phi Eta Sigma Honor Society

2001-2004 Undergraduate Deans List

2001 Undergraduate Scholars awardMonetary award

2002 Undergraduate Conway Endowed Student Nursing AwardMonetary Award

2003 Lucas and Chaffee Memorial Undergraduate Scholars AwardMonetary Award

2003 Sigma Theta Tau, Eta Chapter inductee

2004 BSN Graduation, Honors

2004 BSN Graduation Speaker, Elected

2004-12/2008 Pre-doctoral Intramural Research Training AwardGraduate Partnership Program ScholarNIH/NINRTuition reimbursement and monthly stipend5 Years of Funding

2007 Cover Story, Pitt Nurse, Fall 2007 “From bench to practice to policy”, page 5-8

2009 Inductee, 2010 Who’s Who Among Executives and Professionals Throughout the World

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2009 Cover Story, Pitt Nurse Fall 2009 “Nurses discover hidden links through summer ‘gene camp’

2010 Featured Story, Neurology In Focus, Genomic biomarkers and cellular pathways of ischemic stroke by RNA gene expression profiling

2010 Interview, Sciences Pages of American Academy of Neurology online

2010 First WVU Clinical Translational Science Institute KL2 Scholar

2011 New Investigator Research Award, WVU School of Nursing

2011 Post-Doctoral Fellow, R. VanGilder, selected for Cold Spring Harbor Laboratory Short Course, Molecular Neurology and Neuropathology, June 27-July 3

2012 Featured Story, WVU Health Spring 2012. Family Stories Drive Health Research

2012 2012 HSC Research Day Poster Presentation Winner, Undergraduate Mentee, Noelle Lucke-Wold

2012 WVU School of Nursing, Innovative Teaching in Graduate Education Award

2012 Featured Story with Paul Chantler, WVU Health Fall 2012. A New Era: A Translational Approach to Rural Heart Disease

2013 Feature Story: Wanted: Young Nurse Faculty. Robert Wood Johnson Foundation

2013 Danielle Doll PhD Neuroscience MenteeWVU BBS Predoctoral Fellowship Awardee

ACTIVITIES/MEMBERSHIPS

2000-2004 Member, Nursing Student AssociationUniversity of PittsburghSchool of Nursing

2001-2010 Sigma Theta Tau, Eta Chapter

2002 International Stroke ConferenceNevillewoodFarmington, Pa

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2003 2nd Annual Nursing Forum UPMCPresbyterian HospitalPittsburgh, Pa

2004 3rd Annual Nursing ForumUPMCShadyside HospitalPittsburgh, Pa

2004-2011 Member, Eastern Nursing Research Society

2004-2011 Member, Society of Critical Care Medicine

2004-2009 Member, Doctoral Nursing Student OrganizationCo-chair of endowed nursing scholarship committee

2005, 2006 Symposium on Functional Genomics2007, 2008 Natcher Conference Center

Bethesda, Maryland

2005-2006 Coordinator, Interdisciplinary Qualitative Research Meetings

2006-2011 Member, International Society of Nurses in Genetics

2006-present Journal of Professional NursingReviewer

2007-present Member, American Heart Association

2007-2008 Member, International Society of Nurses in Genetics Research Grant Committee

2009-present Journal of NeurotraumaReviewer

2009-present Biological Research in NursingReviewer

2009-present Stroke, JournalReviewer

2009-Present Grant Reviewer,Neuroscience Nurse Foundation

2010 Summer Genetics Institute ReviewerNational Institute of Nursing Research

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2010 Center for Neuroscience and Regenerative Medicine, Bethesda MD

Biomarkers Core Committee Member

August 2010-January 2013 WVU Institutional Review BoardMember

August 2010-Present Society for Clinical Translational ScienceMember

September 2010 Conference session ModeratorCouncil for the advancement of Nursing Science Conference

October 2010- Present CTSA Nurse Scientist Special Interest Group

October 2010- Present WVU Stroke Initiative Working Group

December 2010- Present WVU Cardiovascular Disease Working Group

November 2010 Interviewer for WVU HSC VP candidates

Fall 2010-Present WVU SON Graduate Faculty Committee

May 2011-July 2012 WVU School of Nursing Research Strategic Planning Advisory Committee

November 2011-February 2012 WVU SON Grants Coordinator Committee

November 2011- February 2012 WVU HSC Bioinformatics Search Committee

March 2012-January 2013 WVU SON PhD Curriculum Change Committee

March 2012-September 2013 WVU Health Sciences Research Advisory Committee

March 2012 WVU HSC Stroke Director Search Committee

May- June 2012 School of Nursing Dean 5 year Evaluation Committee

May 2012-Present Co-Development of WVU HSC initiative, Advancing Cardiovascular Health through Translational Research (ACTS)

June 2012- May 2014 Appointed to the American Heart Associations’ Council on Cardiovascular Nursing, Stroke Nursing Committee

June 2012 WVU CTSI Grant Reviewer

September 2012 CTR Grant, Community Engagement Core Co-leader

September 2012 WV Asthma Camp Genetics Education, Mentees Danielle Doll and Steven Brooks

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February 2013 Grant Reviewer, 2012 Psychological Health and Traumatic Brain Injury Research Program (PH/TBI RP) for the Department of

Defense (DoD) Congressionally Directed Medical Research

Programs (CDMRP)

January 2013-Present WVU Neuroscience Program Literature Review Committee and Curriculum Update Committee

June 2013 Guest Editor, Special Edition for Journal of Aging and Disease

Spring 2013 AHA Subject Based Peer Review Committee Member

Spring 2013-present Microcirculation, Journal Reviewer

Summer 2013-Present Thrombosis and Haemostasis, Journal Reviewer

Summer 2013-Present Annals of Clincal and Translational Neurology, Journal Reviewer

Fall 2013-Present WVU SON Grant Reviewer

Fall 2013-Present WVU SON BSN-PhD Committee, Chair

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