Upload File

central metabolism cofactor biosynthesis · ppp9 pi h h2o ppi h h2o h2o dad-5 h[p] atp adp h pi h2o...

  • Home
  • Documents
  • Central Metabolism Cofactor Biosynthesis · ppp9 pi h h2o ppi h h2o h2o dad-5 h[p] atp adp h pi h2o succoa lipoate atp glx 2p4c2me xu5p-D h2o cbl1 ppi h[e] h2o h dad-5 gthrd asp-L
1
Inorganic Ion Transport 2 2 2 Ubiquinol thiL 2 5 Cofactor Biosynthesis Riboflavin Molybdenum Synthesis 3 Heme Biosynthesis 4 Lipoate dead end 2 NAD/NADP Metabolism Fe-S clusters ATP Synthase 3 2 CoA 3 3 dead end Biotin Enterochelin Converted to GLX 8 Vitamin B12 Transhydrogenase 2 Thiamin 2 (see Central Metabolism Map) Menaquinone methionine synthase Vitamin B6 2 2 Folate 2 3 3 Isoprenoid atp lipoate[e] adocbip h[p] h[p] h adp adp pi h2o pydam g3p h gbbtn[p] adp 10fthf h h nmn[p] h[p] dad-5 h etoh nadh co2 adp amet 2dhp dhnpt atp rdmbzi atp h nh4 lac-L[e] ppi nadph h h[p] o2 nad h h amet h adp pi dxyl sufse crnDcoa glyclt h gtp h2o2 4fe4s atp ahdt ppi pi nadh atp 6pgc h2o nadh h2o for pheme[p] thmnp pi pppi cys-L 4adcho adp mql8 h2o atp fe3 ni2 lipopb pi iscssh h2o h2o h ppi co2 atp amp atp na1 5drib h2o 23dhb h co2 h h nadp g3p adp bmoco1gdp sufbcd nadph h pi pydxn[p] bglycogen bbtcoa coa mn2[p] 4hthr fum[e] thf fmnh2 mg2 h pi btn[e] ala-L h nadh h h cys-L atp coa h2o glc-D[p] h pmeACP fe2 co2 ppi mobd[p] h[p] ppi h h pyr pi nad h2o adp 5apru akg 6hmhptpp fru[e] h2o adp 12ppd-R h dhpmp h2o for h h h octa dhpt amp h atp h ac[p] h pan4p fe2 ctp nadp pi h h na1[p] nadp h[p] for nadp h2o nad ppi gcald ppi atp nh4 h[p] h h adp pi mptamp octapb bwco1gdp adp ppi nadp fadh2 h2o nad adpglc atp q8h2 accoa h h2o ichor 4r5au h q8 h dmbzid co2 pi co2 nadp 3pg nadh co2 atp h2o glyclt[p] co2 glu-L h h2[p] gmp cmp h2o pyr ade cobalt2[p] pi 2tpr3dpcoa nad ppi nadh adp cu2 atp atp asp-L k[p] h2o h fum fe2 h succ h h h2o dhgly xyl-D h for h2o h2o pi h nad h mobd[e] f6p[p] nadph h[p] h2o gtp h2o h2o ppi 5mthf pi nadp nac h[p] co2 pyr[e] pi akg pi g1p[e] h co2 h2o adp ribflv tyr-L ahcys atp atp 4mhetz atp acald ctbt[p] h pydxn h h 2dmmql8 atp g6p h h[p] amet h2o ACP co2 atp o2 h atp frdp lac-D[p] adp pi iscssh cpmp 14dhncoa nad h h pi pyr ppi for[e] h crn[e] glutrna h h h h h adp h h cu2 glyc[e] h ppi mg2[p] fum h2o pi h2o nh4 pi[p] co2 pi iscssh h2o glu-L cph4 g6p[p] h adp h[p] atp prpp h2o fadh2 h ppi mlthf h2o h h mg2[e] r5p cu2 iscu fad atp h ala-L ipdp nadph h2o coa h2o 2me4p h h adp opmeACP gbbtn lipoate[p] cobalt2 h h pi moco h cpppg3 2oph h2o fe2 pi pdx5p nad h atp nadph nadp sufbcd-2fe2s2 h coa 2dmmq8 atp pi h2o gtp 5aop pi nadh h[p] h 5prdmbz crn-D iscu 2fe1s nadh mqn8 ncam na1 crn-D co2[p] h adocbi nadp atp h nicrnt ppi h h ppi nadph co2 pi h2o 2sephchc 2mecdp amp atp cbl1[e] h2o adp co2 sufbcd ppi cit[p] nadh adprib atp cu2[e] h2o nad adp nadp ppi h2o q8h2 nad 2pg bwco 23ddhb pi h co2 h2o mpt atp cl[p] nad h2o adp h2o adp pi pi co2 5fthf nmn[e] agdpcbi h[p] fe2 iscs h nh4 h 2omhmbl h cdg ahcys h[p] pnto-R h2o adp q8 cl pep adp coa akg h[p] ahcys adp glyc3p[e] nad co2 nadp coa pi[p] 2fe2s amet sufsesh 2fe2s amp 23dhba h h h[p] nad atp f1p h2o dhap nmn nadh h2o adp nad co2 fadh2 h acald ppi o2 h2o h2o acon-T adp h h[p] nadp nadp mal-L[e] pi ni2[e] h2o2 nadh h2o h2o h h2o mql8 pep pi iscu-2fe2s2 pi h pi cu2 ppi h2o atp h h h h ocACP glu-L h2o adp g6p[e] pyr meoh[e] h2o rib-D[e] h2o co2 amet atp nadh h nad h gtp h ppi lac-D[e] mobd adp for nad co2 h atp btn[p] nadph glyc dmpp h h fadh2 f6p bwcogdp nad h amp h[p] h[p] h2o2 pyr dhf h ppi pydam[p] nadph h2o ppi pppi amp adp h ppi pi lipoamp h nad h adp amp h[p] ctp h2o h h2o h icit h[p] h2o pi atp nad cbi[p] amp h ppi mn2[e] 2fe2s atp acald[e] pydx pi amet h nh4 lac-D ac fe2 h2o oaa atp h h[p] h bmoco h 4hbz h[p] ppi 2ohph h fadh2 fe2 h2o nadph 5aprbu quln h atp ade h2o 2dmmql8 ala-B[p] preq0 mql8 iscu-2fe2s sufse h adp coa h2o o2 cu[e] malACP nadh 6hmhpt ogmeACP pi thmmp nadh atp h h akg[p] h nad adp ppi fad sufbcd-2fe2s atp atp h acon-C h nadh moadcoo k[e] nadh cu pydx5p ru5p-D glu1sa mthgxl nadph 2fe1s thm h[p] h adocbl[e] for ppi glyc3p cbl1[p] h2o lald-D adp btn ahcys h nad h nadh ca2 ala-D pyr adp h nad amp ac[e] h h2o h atp nh4 h2o h[p] nadph h succ nadph uppg3 tungs h cbi h h2o nadph h nicrnt pi co2 h2o coa nad h h flxr atp h[p] nadp pi h2o nad atp h co2 nad h2o[p] ppi udcpdp h[p] nadph h fadh2 wco akg[e] s17bp glu-L o2 iscssh atp hgmeACP h pi 4crsol h2o nadp fad co2 h atp pap pi ppbng adp ppi o2 na1[p] glyclt[e] amp lac-L[p] adp adp h h2o amet h2o fadh2 accoa pnto-R[e] h[p] h ctp lac-L sufbcd o2[p] h h h[p] nadp nadh adp zn2 succ[e] dmlz h2o nadh h pi succ[p] h pheme[e] amp nadh h h h adp h na1[p] 4ampm h2o nadh h h adp aconm h[p] fe2 nadh for[p] h tungs[e] thmpp ca2[e] nadph nh4 13dpg nadp h2o pi h2[e] moadamp h h xyl-D[e] thm[e] moadcosh h dtbt nadh h crn adp na1 fru[p] atp mptamp mqn8 nh4 mal-L[p] atp pi meoh dhmpt h ahcys dhna h h iscs h2o adp ACP adp adp atp glyc3p[p] h h 5drib ppi 4fe4s atp atp h o2 h2o nh4 pi amp air atp h2o adp amp iscu h atp h2o h[p] atp h cl[e] pep h 23dhbzs h fum[p] amp iscs enter h pyr pep pheme atp nad coa h atp pi h adp nad 12ppd-R[p] h ru5p-D h atp nad h[p] nadh s7p h etoh[p] chor h[p] nadph ni2[p] ala-L ppi gtp prpp 3ophb amob h pyr nadh nadh pydx[e] sucbz amp lgt-S cbi[e] gbbtn[e] h2o h btnso nadph h pyr pyr gtp amet h e4p h2o2 atp pyr sbzcoa atp 2mahmp h sufbcd-4fe4s atp apoACP cys-L bmocogdp mql8 malcoa 3mob h 8aonn ctbtcoa atp nad nad h2o atp pi[p] h[p] ohpb dhmptp h h[p] h2o coa ppi actp nadh nadp ACP adp nadp atp no h2o sufbcd h2o adp atp nadp h h scl pi pi h2o crn-D[e] h 4ppcys dxyl5p xyl-D[p] dnad h h nadph pi adp h fad atp adp h nadh adp pnto-R[p] na1[e] gtp h iscu-4fe4s atp fdp ACP pi 2ommbl h h h h h amet 2fe1s h2o pep dhap coa fe3 ser-L q8 gln-L h sheme h atp h pydam[e] h h2 ppi h 4c2me amp h adp n2o meoh[p] co2 h succ fmn h h2o ala-B h h[p] h2o ppp9 pi h h2o ppi h h2o h2o dad-5 h[p] atp adp h pi h2o succoa lipoate atp glx 2p4c2me xu5p-D h2o cbl1 ppi h[e] h2o h dad-5 gthrd asp-L pi[p] nac mocogdp 4mpetz h2o octdp egmeACP atp pydxn[e] dha ahcys gly adocbl nad pi mql8 h[p] h dpcoa seramp trnaglu iasp iscs pi nad h adp pi amet nadp o2 zn2[p] fad cu2 h ppi pi h2o2 2shchc sufsesh dscl co2[e] etoh[e] h glycogen f6p[e] nad co2 cu2 pppi h 25drapp o2 pyr atp q8 6pgl h2o atp iscu 4abz pimACP met-L adp h r5p 4per h 2omph pyam5p dann dxyl5p nadp cu2[p] succ hmbil grdp h[p] ppi h2o h adp nadph adp nadp r5p coa h[p] ca2[p] gmeACP ac dad-5 ala-B[e] h mqn8 tungs[p] q8h2 mlthf nad atp 3fe4s adocbl[p] h2o epmeACP succ[p] h h nadp nadh h preq1 h 12ppd-R[e] mn2 h 2ddg6p ala-L hemeO nadh h[p] cobalt2[e] cmp adp h coa h zn2[e] h2o[p] mococdp glyc[p] nadp nadph atp ahcys g1p[p] met-L cit nadh h2o nad h h adp pi e4p amp athtp q8h2 pi h hpmeACP met-L fad db4p h crn[p] h h nadph atp amet adp glc-D[e] pi ade adp h2o methf h[p] k h amet nadh coa ppi gtp fad pi nadh h2o pi ppi nadph h2o adp rbflvrd h adp atp phthr h mal-L co2 pyr[p] glc-D cu[p] acald[p] co2 4ppan h2o h pi pi pi pi flxso nadh h2o crn-D[p] nadph atp adp pydx[p] nadp malcoame xylu-D h thm[p] atp atp adp fum h pi atp 4ahmmp pant-R h h h2o h malACP h2o h2o g1p pppg9 atp h co2 atp thf nadph nadph h adp cit[e] h2o h[p] atp met-L rib-D mqn8 crn-D[p] coa rib-D[p] atp 2ombzl atp ppi h h for crncoa h h h2mb4p nad atp q8h2 h h2o atp ctbt GLCtex ADOCBLtonex L-LACD2 MECDPDH5 BMOGDS2 XYLK MALt2_3pp OPMEACPS CPH4S G6PP DHFS H2tex OCTNLL FBA3 BTNtex GLCptspp CO2tex DXPS FESR FADRx2 FORtppi COBALT2tex GLYCL F6Ptex NADDP UDCPDPS CUtex FADRx MTHFD NADS1 CRNDCAL2 GLCP RPE ICHORS MN2tpp G6Pt6_2pp AOXSr2 PPCDC OPHHX3 OPHBDC 2MAHMP OGMEACPD CTBTCAL2 12PPDRtpp NADN 4HTHRS FBA NADK CLt3_2pp AKGDH EGMEACPR EPMEACPR FLVRx SHCHCS3 ACKr GLCP2 OGMEACPR LDH_D DHFR MNt2pp OAADC DM_AMOB PFK_3 OCTDPS DHNAOT4 MALS DHBS PYRtex FRUptspp OMPHHX3 FOMETRi ME2 MG2tpp DHNPA2r LCARR CPPPGO2 E4PD CRNDt2rpp ADOCBLabcpp MALt3pp UPP3MT Kabcpp LIPOt2pp DPCOAK HEX1 F6PA GLUTRS DB4PS ADCL FORt2pp CBIuabcpp NI2abcpp HBZOPT ACBIPGT ADOCBIK S2FE2SS2 DBTS LIPAMPL XYLt2pp SUCCt2_3pp ACtex MEPCT ACONTb CO2tpp PYDXtpp PNTOtex I2FE2SR MG2uabcpp PPCK CRNDabcpp NAtex DHNCOAT OPMEACPR ASPO5 MOHMT CPMPS I2FE2SS2 GLYC3Ptex PTAr BSORy CBL1abcpp 12PPDRtex G3PD2 DHBSH ADCS I4FE4SR TPRDCOAS TUNGStex MTHFR2 ALDD2x OHPBAT I2FE2SS CITt3pp NI2tex FCLT CRNCBCT OMMBLHX3 ASP1DC CUt3 CTBTt2rpp PNTK OMBZLM SERASr IPDPS HEMEOS ThDPAT ALATA_D2 TKT2 MALt2_2pp MG2tex ACALD RZ5PP GLBRAN2 NMNN GCALDD FESD1s GTPCII2 LALDO2x DHBD AMMQLT8 PYK PYDXNK AKGt2rpp MOGDS G6PDH2r FHL ACPS1 GLCptspp IPDDI CBLAT ACALDtex PYDAMtpp ZN2t3pp CRNDtex MPTS HMPK1 TALA DXYLK FRD3 FORtex ASPO6 CTBTabcpp PGK CU1abcpp PANTS NADTRHD S4FE4ST MNtex CITtex DHPS2 CHRPL MN2t3pp L-LACtex NAt3pp NMNAT ETOHtrpp CBItonex NNAM ICHORSi ADOCBLS CRNCAR Kt3pp CPPPGO THMabcpp XYLI1 MG2t3_2pp D-LACtex S2FE2SR FMNRx2 UPP3S ALCD2x PYRt2rpp ZN2abcpp DHPPDA2 PYDAMK PERD DM_5DRIB GLGC MPTSS DNTPPA CAt6pp GLCS1 BWCOGDS1 CRNCDH NAt3_2pp EDD GLYCtpp AMAOTr FRUK FBP LIPOS FTHFLi Kt2pp CRNtex XYLtex TMPK ASPO4 RIBabcpp ENTCS BSORx SUCBZL RBK DMATT THMtex LIPOCT GBBTNtex PYDXPP DHAPT FUMt2_3pp MALtex CU2abcpp FUMt2_2pp DHMPTR NNDMBRT SHCHF BWCOGDS2 PGM AMPMS2 GLYC3Pt6pp G1Ptex ICYSDS BMOGDS1 PDX5PO2 PPC PDX5PS 5DOAN CRNt7pp SUCCt3pp BMOCOS UPPDC1 FMNRx LGTHL SUCCtex I4FE4ST OGMEACPS BALAtex CRNBTCT NAt3_1p5pp CRNCAL2 LIPOtex MOX MEOHtex MECDPS BWCOS PPPGO3 ACONTa GTPCI CLtex CITt7pp DHPTPE ICL CCGS EDA RBFSb Zn2tex ALATA_L2 NNATr CRNt8pp NNDPR CRNt2rpp D-LACt2pp COBALT2abcpp XYLabcpp CA2t3pp PYDXK PYDXtex DM_4CRSOL GLYCLTtex NADPPPS FRUpts2pp DPR I2FE2ST MOCDS GLYC3Pabcpp MGSA MDH3 G1SAT OPMEACPD TUNGSabcpp SUCCt2_2pp GLYCLTt4pp MOBDtex PYDXNtex PTPATi PGL OMMBLHX FESD2s APRAUR CA2tex TYRL MTHFC THFAT PGMT BTS5 ACONMT MPTAT HMBS COBALT2tpp PDH GND AKGtex GLCt2pp G3PT CBIAT G1PPpp ICDHyr TMK MALCOAMT SEPHCHCS CS PHEMEtiex PMPK MDH CU1Opp PPPGO ENO Ktex TDP CU2tex TKT1 PPNCL2 PGI GLYK MOADSUx PNTOt4pp ACALDtpp ZNabcpp OPHHX H2tpp DNMPPA ASPO3 RBFSa DHNPTE NMNtex GRTT FRUtex ZN2tpp HPPK2 L-LACt2rpp NI2tpp SCYSDS CDGS NMNDA FUMtex DMQMT ATPS4rpp PHEMEabcpp HETZK ALDD2y PMEACPE L-LACD3 F6Pt6_2pp SUCBZS NMNt7pp PFK CU2tpp CITL NAMNPP S2FE2SS PYDAMtex PDXPP RPI RIBtex COBALT2t3pp MOCOS LIPATPT FUM MDH2 THD2pp CDGR FRD2 G6Ptex RBFK S2FE2ST QULNS GLYCLTt2rpp HYPOE GAPD GLDBRAN2 DXPRIi MOBDabcpp ETOHtex TMPPP CDPMEK BTNt2ipp 5DOAN ACONIs CBL1tonex DHNCOAS SUCOAS CRNabcpp PYDXNtpp PDX5POi NI2t3pp ACS NMNPtpp WCOS OHPHM PMDPHT ICHORT TPI GLYCtex FTHFD BALAt2pp DMPPS ACt2rpp ME1 FLVR PYAM5PO GLYOX OMPHHX SHCHD2 S4FE4SR SUCDi PPBNGS FMNAT MEOHtrpp GLUTRR THZPSN3 PPS NI2uabcpp PFL GLYCDx Central Metabolism Figure S4

Upload: others

Post on 14-Jul-2020

14 views

Category:

Documents


0 download

Report

TRANSCRIPT

Page 1: Central Metabolism Cofactor Biosynthesis · ppp9 pi h h2o ppi h h2o h2o dad-5 h[p] atp adp h pi h2o succoa lipoate atp glx 2p4c2me xu5p-D h2o cbl1 ppi h[e] h2o h dad-5 gthrd asp-L

Inorganic Ion Transport

2

2

2

Ubiquinol

thiL

2

5

Cofactor Biosynthesis

Riboflavin

Molybdenum Synthesis

3

Heme Biosynthesis

4

Lipoate

dead end

2

NAD/NADP Metabolism

Fe-S clusters

ATPSynthase

3

2

CoA

33

dead end

Biotin

Enterochelin

Converted to GLX

8

Vitamin B12

Transhydrogenase

2

Thiamin

2

(see Central Metabolism Map)Menaquinone

methionine synthase

Vitamin B6

2 2

Folate2

33

Isoprenoid

atp

lipoate[e]

adocbip

h[p]

h[p]

h

adp

adp

pi

h2o

pydam

g3p

h

gbbtn[p]

adp

10fthf

h

h

nmn[p]

h[p]

dad-5

h

etoh

nadh

co2

adp

amet

2dhp

dhnpt

atp

rdmbzi

atp

h

nh4

lac-L[e]

ppi

nadph

h

h[p]

o2

nad

h

h

amet

h

adp

pi

dxyl

sufse

crnDcoa

glyclt

h

gtp

h2o2

4fe4s

atp

ahdt

ppi

pi

nadh

atp

6pgc

h2o

nadh

h2o

for

pheme[p]

thmnp

pi

pppi

cys-L

4adcho

adp

mql8

h2o

atp

fe3

ni2

lipopb

pi

iscssh

h2o

h2o

h

ppi

co2

atp

amp

atp

na1

5drib

h2o

23dhb

h

co2

h

h

nadp

g3p

adp

bmoco1gdp

sufbcd

nadph

h

pi

pydxn[p]

bglycogen

bbtcoa

coa

mn2[p]

4hthr

fum[e]

thf

fmnh2

mg2

h

pi

btn[e]

ala-L

h

nadh

h

hcys-L

atp

coa

h2o

glc-D[p]

h

pmeACP

fe2

co2

ppi

mobd[p]

h[p]

ppi

h

h

pyr

pi

nad

h2o

adp

5apru

akg

6hmhptpp

fru[e]

h2o

adp

12ppd-R

h

dhpmp

h2o

for

h

h

h

octa

dhpt

amp

h

atp

h

ac[p]h

pan4p

fe2

ctp

nadp

pi

h

h

na1[p]

nadp

h[p]

for

nadp

h2o

nad

ppi

gcald

ppi

atp

nh4

h[p]

h

h

adp

pi

mptamp

octapb

bwco1gdp

adp

ppi

nadp

fadh2

h2o

nad

adpglc

atp

q8h2

accoa

h

h2o

ichor

4r5au

h

q8

h

dmbzid

co2

pi

co2

nadp

3pg

nadh

co2

atp

h2o

glyclt[p]

co2

glu-L

h

h2[p]

gmp

cmp

h2o

pyr

ade

cobalt2[p]

pi

2tpr3dpcoa

nad

ppi

nadh

adp

cu2

atp

atp

asp-L

k[p]

h2o

h

fum

fe2

h

succ

h

h

h2o

dhgly

xyl-D

h

for

h2o

h2o

pi

h

nad

h

mobd[e]

f6p[p]

nadph

h[p]

h2o

gtp

h2o

h2o

ppi

5mthf

pi

nadp

nac

h[p]

co2

pyr[e]

pi

akg

pi

g1p[e]

h

co2

h2o

adp

ribflv

tyr-L

ahcys

atp

atp

4mhetz

atp

acald

ctbt[p]

h

pydxn

h

h

2dmmql8

atp

g6p

h

h[p]

amet

h2o

ACP

co2

atp

o2

h

atp

frdp

lac-D[p]

adp

pi

iscssh

cpmp

14dhncoa

nad

h

h

pi

pyr

ppi

for[e]

h

crn[e]

glutrna

h

h

h

h

h

adp

h

h

cu2

glyc[e]

h

ppi

mg2[p]

fum

h2o

pi

h2o

nh4

pi[p]

co2

pi

iscssh

h2o

glu-L

cph4

g6p[p]

h

adp

h[p]

atp

prpp

h2o

fadh2

h

ppi

mlthf

h2o

h

h

mg2[e]

r5p

cu2

iscu

fad

atp

h

ala-L

ipdp

nadph

h2o

coa

h2o

2me4p

h

h

adp

opmeACP

gbbtn

lipoate[p]

cobalt2

h

h

pi

moco

h

cpppg3

2oph

h2o

fe2

pi

pdx5p

nad

h

atp

nadph

nadp

sufbcd-2fe2s2

h

coa

2dmmq8

atp

pih2o

gtp

5aop

pi

nadh

h[p]

h

5prdmbz

crn-D

iscu

2fe1s

nadh

mqn8

ncam

na1

crn-D

co2[p]

h

adocbi

nadp

atp

h

nicrnt

ppi

h

h

ppi

nadph

co2

pi

h2o

2sephchc

2mecdp

amp

atp

cbl1[e]

h2o

adp

co2

sufbcd

ppi

cit[p]

nadh

adprib

atp

cu2[e]

h2o

nad

adp

nadp

ppi

h2o

q8h2

nad

2pg

bwco

23ddhb

pi

h

co2

h2o

mpt

atp

cl[p]

nad

h2o

adp

h2o

adp

pi

pi

co2

5fthf

nmn[e]

agdpcbi

h[p]

fe2

iscs

h

nh4

h

2omhmbl

h

cdg

ahcys

h[p]

pnto-R

h2o

adp

q8

cl

pep

adp

coa

akg

h[p]

ahcys

adp

glyc3p[e]

nad

co2

nadp

coa

pi[p]

2fe2s

amet

sufsesh

2fe2s

amp

23dhba

h

h

h[p]

nad

atp

f1p

h2o

dhap

nmn

nadh

h2o

adp

nad

co2

fadh2

h

acald

ppi

o2

h2o

h2o

acon-T

adp

h

h[p]

nadp

nadp

mal-L[e]

pi

ni2[e]

h2o2

nadh

h2o

h2o

h

h2o

mql8

pep

pi

iscu-2fe2s2

pi

h

pi

cu2

ppi

h2o

atp

h

h

h

h

ocACP

glu-L

h2o

adp

g6p[e]

pyr

meoh[e]

h2o

rib-D[e]

h2o

co2

amet

atp

nadh

h

nad

h

gtp

h

ppi

lac-D[e]

mobd

adp

for

nad

co2

h

atp

btn[p]

nadph

glyc

dmpp

h

h

fadh2

f6p

bwcogdp

nad

h

amp

h[p]

h[p]

h2o2

pyr

dhf

h ppi

pydam[p]

nadph

h2oppi

pppi

amp

adp

h

ppi

pi

lipoamp

h

nad

h

adp

amp

h[p]

ctp

h2o

h

h2o

h

icit

h[p]

h2o

pi

atp

nad

cbi[p]

amp

h

ppi

mn2[e]

2fe2s

atp

acald[e]

pydx

pi

amet

h

nh4

lac-D

ac

fe2

h2o

oaa

atp

h

h[p]

h

bmoco

h

4hbz

h[p]

ppi

2ohph

h

fadh2

fe2

h2o

nadph

5aprbu

quln

h

atp

ade

h2o

2dmmql8

ala-B[p]

preq0

mql8

iscu-2fe2s

sufse

h

adp

coa

h2o

o2

cu[e]

malACP

nadh

6hmhpt

ogmeACP

pi

thmmp

nadh

atp

h

h

akg[p]

h

nad

adp

ppi

fad

sufbcd-2fe2s

atp

atp

h

acon-C

h

nadh

moadcoo

k[e]

nadh

cu

pydx5p

ru5p-D

glu1sa

mthgxl

nadph

2fe1s

thm

h[p]

h

adocbl[e]

for

ppi

glyc3p

cbl1[p]

h2o

lald-D

adp

btn

ahcys

h

nad

h

nadh

ca2

ala-D

pyr

adp

h

nad

amp

ac[e]

h

h2o

h

atp

nh4

h2o

h[p]

nadph

h

succ

nadph

uppg3

tungs

h

cbi

h

h2o

nadph

h

nicrnt

pi

co2

h2o

coa

nad

h

h

flxr

atp

h[p]

nadp

pi

h2o

nad

atp

h

co2

nad

h2o[p]

ppi

udcpdp

h[p]

nadph

h

fadh2

wco

akg[e]

s17bp glu-L

o2

iscssh

atp

hgmeACP

h

pi

4crsol

h2o

nadp

fad

co2

h

atp

pap

pi

ppbng

adp

ppi

o2

na1[p]

glyclt[e]

amp

lac-L[p]

adp

adp

h

h2o

amet

h2o

fadh2

accoa

pnto-R[e]

h[p]

h

ctp

lac-L

sufbcd

o2[p]

h

h

h[p]

nadp

nadh

adp

zn2

succ[e]

dmlz

h2o

nadh

h

pi

succ[p]

h

pheme[e]

amp

nadh

h

h

h

adp

h

na1[p]

4ampm

h2o

nadh

h

h

adp

aconm

h[p]

fe2

nadh

for[p]

h

tungs[e]

thmpp

ca2[e]

nadph

nh4

13dpg

nadp

h2o

pi

h2[e]

moadamp

h

h

xyl-D[e]

thm[e]

moadcosh

h

dtbt

nadh

h

crn

adp

na1

fru[p]

atp

mptamp

mqn8

nh4

mal-L[p]

atp

pi

meoh

dhmpt h

ahcys

dhna

h

h

iscs

h2o

adp

ACP

adp

adp

atp

glyc3p[p]

h

h

5drib

ppi

4fe4s

atp

atp

h

o2

h2o

nh4

pi

amp

air

atp

h2o

adp

amp

iscu

h

atp

h2o

h[p]

atp

h

cl[e]

pep

h

23dhbzs

h

fum[p]

amp

iscs

enter

h

pyr

pep

pheme

atp

nad

coa

h

atp

pi

h

adp

nad

12ppd-R[p]

h

ru5p-D

h

atp

nad

h[p]

nadh

s7p

h

etoh[p]

chor

h[p]

nadph

ni2[p]

ala-L

ppi

gtp

prpp

3ophb

amob

h

pyr

nadh

nadh

pydx[e]

sucbz

amp

lgt-S

cbi[e]

gbbtn[e]

h2o

h

btnso

nadph

h

pyr

pyr

gtp

amet

h

e4p

h2o2

atp

pyr

sbzcoa

atp

2mahmp

h

sufbcd-4fe4s

atp

apoACP

cys-L

bmocogdp

mql8

malcoa

3mob

h

8aonn

ctbtcoa

atp

nad

nad

h2o

atp

pi[p]

h[p]

ohpb

dhmptp

h

h[p]h2o

coa

ppi

actp

nadh

nadp

ACP

adp

nadp

atp

no

h2o

sufbcd

h2o

adp

atp

nadp

h

h

scl

pi

pih2o

crn-D[e]

h

4ppcys

dxyl5p

xyl-D[p]

dnad

h

h

nadph

pi

adp

h

fad

atp

adp

h

nadh

adp

pnto-R[p]

na1[e]

gtp

h

iscu-4fe4s

atp

fdp

ACP

pi

2ommbl

h

h

h

h

h

amet

2fe1s

h2o

pep

dhap

coa

fe3

ser-L

q8

gln-L

h

sheme

h

atp

h

pydam[e]

h

h2

ppi

h

4c2me

amp

h

adp

n2o

meoh[p]

co2

h

succ

fmn

h

h2o

ala-B

h

h[p]

h2o

ppp9

pi

h

h2o

ppi

h

h2o

h2o

dad-5

h[p]

atp

adp

h

pi

h2o

succoa

lipoate

atp

glx

2p4c2me

xu5p-D

h2o

cbl1

ppi

h[e]

h2o

h

dad-5

gthrd

asp-L

pi[p]

nac

mocogdp

4mpetz

h2o

octdp

egmeACP

atp

pydxn[e]

dha

ahcys

gly

adocbl

nad

pi

mql8

h[p]

h

dpcoa

seramp

trnaglu

iasp

iscs

pi

nad

h

adp

pi

amet

nadp

o2

zn2[p]

fad

cu2

h ppi

pi

h2o2

2shchc

sufsesh

dscl

co2[e]etoh[e]

h

glycogen

f6p[e]

nad

co2

cu2

pppi

h

25drapp

o2

pyr

atp

q8

6pgl

h2o

atp

iscu

4abz

pimACP

met-L

adp

h

r5p

4per

h

2omph

pyam5p

dann

dxyl5p

nadp

cu2[p]

succ

hmbil

grdp

h[p]

ppi

h2o

h

adp

nadph

adp

nadp

r5p

coa

h[p]ca2[p]

gmeACP

ac

dad-5

ala-B[e]

h

mqn8

tungs[p]

q8h2

mlthf

nad

atp

3fe4s

adocbl[p]

h2o

epmeACP

succ[p]

h

h

nadp

nadh

h

preq1

h

12ppd-R[e]

mn2

h

2ddg6p

ala-L

hemeO

nadh

h[p]

cobalt2[e]

cmp

adp

h

coa

h

zn2[e]

h2o[p]

mococdp

glyc[p]

nadp

nadph

atp

ahcys

g1p[p]

met-L

cit

nadh

h2o

nad

h

h

adp

pi

e4p

amp

athtp

q8h2

pi

h

hpmeACP

met-L

fad

db4p

h

crn[p]

h

h

nadph

atp

amet

adp

glc-D[e]

pi

ade

adp

h2o

methf

h[p]

k

h

amet

nadh

coa

ppi

gtp

fad

pi

nadh

h2o

pi

ppi

nadph

h2o

adp

rbflvrd

h

adp

atp

phthr

h

mal-L

co2

pyr[p]

glc-D

cu[p]

acald[p]

co2

4ppan

h2o

h

pi

pi

pi

pi

flxso

nadh

h2o

crn-D[p]

nadph

atp

adp

pydx[p]

nadp

malcoame

xylu-D

h

thm[p]

atp

atp

adp

fum

h

pi

atp

4ahmmp

pant-R

h

h

h2o

h

malACP

h2o

h2o

g1p

pppg9

atp

h

co2

atp

thf

nadph

nadph

h

adp

cit[e]

h2o

h[p]

atp

met-L

rib-D

mqn8

crn-D[p]

coa

rib-D[p]

atp

2ombzl

atp

ppi

h

h

for

crncoa

h

h

h2mb4p

nad

atp

q8h2

h

h2o

atp

ctbt

GLCtex

ADOCBLtonex

L-LACD2

MECDPDH5

BMOGDS2

XYLK

MALt2_3pp

OPMEACPS

CPH4S

G6PP

DHFS

H2tex

OCTNLL

FBA3

BTNtex

GLCptspp

CO2tex

DXPS

FESR

FADRx2

FORtppi

COBALT2tex

GLYCL

F6Ptex

NADDP

UDCPDPS

CUtex

FADRx

MTHFD

NADS1

CRNDCAL2

GLCP

RPE

ICHORS

MN2tpp

G6Pt6_2pp

AOXSr2

PPCDC

OPHHX3

OPHBDC

2MAHMP

OGMEACPD

CTBTCAL2

12PPDRtpp

NADN

4HTHRS

FBA

NADK

CLt3_2pp

AKGDH

EGMEACPR

EPMEACPR

FLVRx

SHCHCS3

ACKr

GLCP2

OGMEACPR

LDH_D

DHFR

MNt2pp

OAADC

DM_AMOB

PFK_3

OCTDPS

DHNAOT4

MALS

DHBS

PYRtex

FRUptspp

OMPHHX3

FOMETRi

ME2

MG2tpp

DHNPA2r

LCARR

CPPPGO2

E4PD

CRNDt2rpp

ADOCBLabcpp

MALt3pp

UPP3MT

Kabcpp

LIPOt2pp

DPCOAK

HEX1

F6PA

GLUTRS

DB4PS

ADCL

FORt2pp

CBIuabcpp

NI2abcpp

HBZOPT

ACBIPGT

ADOCBIK

S2FE2SS2

DBTS

LIPAMPL

XYLt2pp

SUCCt2_3pp

ACtex

MEPCT

ACONTb

CO2tpp

PYDXtpp

PNTOtex

I2FE2SR

MG2uabcpp

PPCK

CRNDabcpp

NAtex

DHNCOAT

OPMEACPR

ASPO5

MOHMT

CPMPS

I2FE2SS2

GLYC3Ptex

PTAr

BSORy

CBL1abcpp12PPDRtex

G3PD2

DHBSH

ADCS

I4FE4SR

TPRDCOAS

TUNGStex

MTHFR2

ALDD2x

OHPBAT

I2FE2SS

CITt3pp

NI2tex

FCLT

CRNCBCT

OMMBLHX3

ASP1DC

CUt3

CTBTt2rpp

PNTK

OMBZLM

SERASr

IPDPS

HEMEOS

ThDPAT

ALATA_D2

TKT2

MALt2_2pp

MG2tex

ACALD

RZ5PP

GLBRAN2

NMNN

GCALDD

FESD1s

GTPCII2

LALDO2x

DHBD

AMMQLT8

PYK

PYDXNK

AKGt2rpp

MOGDS

G6PDH2r

FHL

ACPS1

GLCptspp

IPDDI

CBLAT

ACALDtex

PYDAMtpp

ZN2t3pp

CRNDtex

MPTS

HMPK1

TALA

DXYLK

FRD3

FORtex

ASPO6

CTBTabcpp

PGK

CU1abcpp

PANTS

NADTRHD

S4FE4ST

MNtex

CITtex

DHPS2

CHRPL

MN2t3pp

L-LACtex

NAt3pp

NMNAT

ETOHtrpp

CBItonex

NNAM

ICHORSi

ADOCBLS

CRNCAR

Kt3pp

CPPPGO

THMabcpp

XYLI1

MG2t3_2pp

D-LACtex

S2FE2SR

FMNRx2

UPP3S

ALCD2x

PYRt2rpp

ZN2abcpp

DHPPDA2

PYDAMK

PERD

DM_5DRIB

GLGC

MPTSS

DNTPPA

CAt6pp

GLCS1

BWCOGDS1

CRNCDH

NAt3_2pp

EDDGLYCtpp

AMAOTr

FRUKFBP

LIPOS

FTHFLi

Kt2pp

CRNtex

XYLtex

TMPK

ASPO4

RIBabcppENTCS

BSORx

SUCBZL

RBK

DMATT

THMtex

LIPOCT

GBBTNtex

PYDXPP

DHAPT

FUMt2_3pp

MALtex

CU2abcpp

FUMt2_2pp

DHMPTR

NNDMBRT

SHCHF

BWCOGDS2

PGM

AMPMS2

GLYC3Pt6pp

G1Ptex

ICYSDS

BMOGDS1

PDX5PO2

PPC

PDX5PS

5DOAN

CRNt7pp

SUCCt3pp

BMOCOS

UPPDC1

FMNRx

LGTHL

SUCCtex

I4FE4ST

OGMEACPS

BALAtex

CRNBTCT

NAt3_1p5pp

CRNCAL2

LIPOtex

MOX

MEOHtex

MECDPS

BWCOS

PPPGO3

ACONTa

GTPCI

CLtex

CITt7pp

DHPTPE

ICL

CCGS

EDA

RBFSb

Zn2tex

ALATA_L2

NNATr

CRNt8pp

NNDPR

CRNt2rpp

D-LACt2pp

COBALT2abcpp

XYLabcpp

CA2t3pp

PYDXK

PYDXtex

DM_4CRSOL

GLYCLTtex

NADPPPS

FRUpts2pp

DPR

I2FE2ST

MOCDS

GLYC3Pabcpp

MGSA

MDH3

G1SAT

OPMEACPD

TUNGSabcpp

SUCCt2_2pp

GLYCLTt4pp

MOBDtex

PYDXNtex

PTPATi

PGL

OMMBLHX

FESD2s

APRAUR

CA2tex

TYRL

MTHFC

THFAT

PGMT

BTS5

ACONMT

MPTAT

HMBS

COBALT2tpp

PDH

GND

AKGtex

GLCt2pp

G3PT

CBIAT

G1PPpp

ICDHyr

TMK

MALCOAMT

SEPHCHCS

CS

PHEMEtiex

PMPK

MDH

CU1Opp

PPPGO

ENO

Ktex

TDP

CU2tex

TKT1

PPNCL2

PGI

GLYK

MOADSUx

PNTOt4pp

ACALDtpp

ZNabcpp

OPHHX

H2tpp

DNMPPA

ASPO3

RBFSa

DHNPTE

NMNtex

GRTT

FRUtex

ZN2tpp

HPPK2

L-LACt2rpp

NI2tpp

SCYSDS

CDGS

NMNDA

FUMtex

DMQMT

ATPS4rpp

PHEMEabcpp

HETZK

ALDD2y

PMEACPE

L-LACD3

F6Pt6_2pp

SUCBZS

NMNt7pp

PFK

CU2tpp

CITL

NAMNPP

S2FE2SS

PYDAMtex

PDXPP

RPIRIBtex

COBALT2t3pp

MOCOS

LIPATPT

FUM

MDH2

THD2pp

CDGR

FRD2

G6Ptex

RBFK

S2FE2ST

QULNS

GLYCLTt2rpp

HYPOE

GAPD

GLDBRAN2

DXPRIi

MOBDabcpp

ETOHtex

TMPPP

CDPMEK

BTNt2ipp

5DOAN

ACONIs

CBL1tonex

DHNCOAS

SUCOAS

CRNabcpp

PYDXNtpp

PDX5POi

NI2t3pp

ACS

NMNPtpp

WCOS

OHPHM

PMDPHT

ICHORT

TPI

GLYCtex

FTHFD

BALAt2pp

DMPPS

ACt2rpp

ME1

FLVR

PYAM5PO

GLYOX

OMPHHX

SHCHD2

S4FE4SR

SUCDi

PPBNGS

FMNAT

MEOHtrpp

GLUTRR

THZPSN3

PPS

NI2uabcpp

PFL

GLYCDx

Central Metabolism

Figure S4

LASER PROCESSING LABORATORY · Rubis, 694 nm Au, Ni and C Pure H2O Pure H2O Pure H2O, NaCl, phtalazine Pure H2O, SDS, CTAB SDS Pure H2O Pure H2O Tsuji (2002), (2003) - Nd:YAG, 1064,

MITOCHONDRIA STRUCTURE - libvolume8.xyzlibvolume8.xyz/zoology/semester2/cellbiology/ultrastructureof... · reaksi pembentukan energi c6 (h2o)6 + h2o o2 + 4h + + 4 e nadp + + 2 h +

H2O World - H2O Rains with Databricks Cloud

Supplementary Information Ludwig LiCoPO4 Microwave ...0.2 C 130 mAh/g 10 LCP/C LiCH 3COO ∙ H2O NH 4CoPO 4 ∙ H2O (from (NH 4)3PO 4 ∙ 3 H2O) ethanol 400 °C 2 h nanosheets (2 nm

Dissociation of H 2 O:H 2 O ↔ H + + OH - K w = a H+ a OH- a H2O Under dilute conditions: a i = [i] And a H2O = 1 Hence: K w = [H + ] [OH - ] At 25 o C

Name_____________________€¦  · Web viewa. common names: NH3 (ammonia), H2O2 (hydrogen peroxide) and H2O (water) b. molecules that begin with H (except H2O) 1. no prefix for H

h2o - Amazon Web Servicesh2o-release.s3.amazonaws.com/h2o/rel-tukey/6/docs-website/h2o-r/h2... · h2o.week ... ModelAccessors . . . . . . . . . . . . . . . . . . . . . . . . . .

Package ‘h2o’ - mran.microsoft.com · Package ‘h2o’ June 17, 2018 Version 3.20.0.2 Type Package Title R Interface for 'H2O' Date 2018-06-15 Description R interface for 'H2O',

PPI all pages v2.qxd - The PPI Group

H2O for Medicine and Intro to H2O in Python

1 L H2O = 1 kg H2O Thus, 75 kg body weight X 60% body water = 45 kg H2O = 45 L H2O

Lisa H. Coleman (SAIC) - David A. Rutan (AS&M) - CERES...8 0.4375 0.4975 22857 20101 1 O3 & H2O 1 O3 & H2O 9 0.4975 0.5950 20101 16807 1 O3 & H2O 1 O3 & H2O 10 0.5950 0.6896 16807

CHEM 2410 Fall 2017 Mid-Term Exam 2 10-25-17 Time: … Exam 2 for WebSite.pdfA) H2O/H+ B) H2O/Peroxide C) OH- D) BH3 E) 1) BH3 2) HO-, H2O2, H2O . 14) Which of the following structures

H2O World - H2O Deep Learning with Arno Candel

,H O) Ta (O,OH) (H O), a new microlite- group mineral from ......Revision 1 32 33 ABSTRACT 34 35 Hydrokenomicrolite, ( ,H2O)2Ta2(O,OH)6(H2O) or ideally 2Ta2[O4(OH)2](H2O), is a new

Peptic ulcer surgery in the PPI and H. pylori era 2017... · Peptic ulcer surgery in the PPI and H. pylori era Dr Leanne Prodehl Surgical Gastroenterology Unit - Charlotte Maxeke

S H O PPI N G L I CHFI ELD - Rowley Hughes Thompson

H2O, the secret of lifefac.ksu.edu.sa/sites/default/files/buffers.pdf · H2O, the secret of life.Water is neutral but it ionizes to a small degree H2O H+ + OH- 1 mole H2O = 18 g 1

Acids and Bases H-A + H2O A- + H3O+ Acids and Bases Acids and

Anti-H 2 PPI Anti-H 2 : ricerca di un lead compound da agonista ad antagonista

Chem 104A, UC, Berkeleynanowires.berkeley.edu/teaching/104a/201418.pdfHCl + NaOH ---> H2O+ NaCl stronger acid stronger base ... Hn A H2O Hn 1A H3O NH H O NH ... BH CO H B C O AlCl

Productionizing H2O Models with Apache Spark · 2018-10-18 · Productionizing H2O Models with Apache Spark Jakub Háva, [email protected] https: ... Spark Transformers H 2O MOJO Model

PPI · Phone +49 (0) 9872 9788-0 | Fax +49 (0) 9872 9788-77 | | [email protected] Ampoules Ampullen Ampoules Ampollas PPI Quality. Packaging. Solutions. Form C d h Ampoules Ampullen

H2 O Glue Other Products Other Proro H2O · H2O Glue Stic H2O Glue AqAqu H2O Glue Adh H2O Glue Poo H2O Glue SlipSp id 2 rwater appll H O Glue roro 2 Other P H O Glue 1.800.220.1966

Week 1 H2O Properties, Solutes Interactions & Types of H2O

Drug Class Review on Proton Pump Inhibitors...Prevention of NSAID-induced ulcer: PPI vs H2-RA 20 Question 2i. Helicobacter pylori eradication: PPI vs PPI 22 Question 2j. H. pylori

H2O on Hadoop - Amazon S3s3.amazonaws.com/h2o-release/h2o/master/1663/docs...H2O – The Open Source Math Engine. H2O on Hadoop Introduction H2O is the open source math & machine learning

H2O World - Collaborative, Reproducible Research with H2O - Nick Elprin

AP* Stoichiometry Free Response Questions KEY...= 0.0637 mol H2O or 3.21 g BeC2O4⋅3 H2O − 2.06 g BeC2O4 = 1.15 g H2O 0.0639 molH O 1802 g mol H O 1.15 g H O 2 2 1 2 =. − use

Machine Learning with R and H2O - H2O.ai Documentationdocs.h2o.ai/h2o/latest-stable/h2o-docs/booklets/RBooklet.pdf · Machine Learning with R and H2O by Mark Landry with assistance

PPI SERVICE PPI CAUTION! PPI - Precision Power Manuals/Precision_Power... · Thank you for choosing PPI audio epuipment. Now, HANG ON! PPI products are engineered and manufactured

ベンゼン環を含む - Coocantakahiko.life.coocan.jp/univ/2012/121107_25_aromatic.pdfOH ONa NaOH +H2O ONa O Na O C O O H C O O OH C O O Na Na OH C O OH O H H OH COOH +H2O 62 LEFEFCp

PHOTOSYNTHESIS · Photosynthesis in purple non-sulfur bacteria CO2 + 2CH3CHOHCH3 C(H2O) + 2CH3COCH3+ H2O isopropanol acetone CO2 + 2 CH3CHOHCOOH C(H2O) + 2 CH3COHCOOH + H2O lactate

UDICELL and EXACTFLO Filters - ASK Chemicals › ... › Minibooklet_Filters_EN.pdf · 2019-06-12 · UDICELL and EXACTFLO Filters 6 Ppi 10 ppi 15 ppi 20 ppi 30 ppi. UDICELL Zirconia

GBM in H2O with Cliff Click: H2O API