nmiopth

Nuclear Medicine Week 2006

Nuclear Medicine In Opthalmology

Dr.V.SIVASUBRAMANIYAN

Dept.Of Nuclear Medicine

SRI SATHYA SAI INSTITUTE OF HIGHER MEDICAL SCIENCES,

Prashanthinilaym.

? NUCLEAR MEDICINE

INTERNAL ADMINISTRATION OF RADIO-ACTIVE ISOTOPES FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES IS TERMED AS NUCLEAR MEDICINE

DIAGNOSTIC APPLICATIONS

DACRYOSCINTIGRAPHY GALLIUM SCAN I-131 MIBG SCANS I-131 BZA SCANS RADIOIMMUNOSCINTIGRAPHY PET – CT EVALUATION

NUCLEAR THERAPY

Gamma emitters

Brachytherapy

Radio-immunotherapy

Yttrium Application in Pterygium

Yt.90 LIMBAL APPLICATION

Pterygium Treatment Protocol

Includes Post-surgical Limbal Yt-90 appication with applicator

Reduces the recurrence to < 5 %

Nasolacrimalduct Apparatus

LACRIMAL PASSAGE IMAGING

INVSIVE IMAGING CONTRAST

DACRYOCYSTOGRAPHY NON-INVASIVE IMAGING DACRYOSCINTIGRAPHY Helical C.T evaluation M. R dacryocystography

Contrast Dacryocystography

Advantage Good Anatomical Delineation Therapeutic Sometimes Disadvantages Radiation Burden Contrast Reactions Non- Physiological

DACRYOSCINTIGRAPHY

Scintigraphic evaluation of Nasolacrimal Duct evaluation

Radiopharmaceutical – Tc99m Pertech.

Dose 50 microcurie

METHODOLOGY

Route : TOPICAL APPLICATION Position: Supine or Sitting Site : Lower eyelid Instrumentation :

Micropipette,Gc Dynamic Acquisition Delayed Images

INDICATIONS

Advantage Dacryoscintigraphy

Absolutely Non-invasive

Dry Run instruction possible

No Contrast agents

No hazards of Allergic reactions

RADIATION DOSE TO LENS

NORMAL EYE 2.2x10(-5) Rad/micro curie

Obstructed EYE 4.0X10(-3)Rad/micro curie

J.ROBERTSON etal Radiology Vol 133,

747-750, 1979

Cost Benefit Analysis

No additional Financial burden Micro-curie dose only Helps in limiting the Wastage Machine time is scheduled in a

such a way other major studies are nor affected.

MR DACRYOCYSTOGRAPHY

Advantage Good Soft Tissue Delineation Funcitonal evaluation possible Disadvantage Costly Not affordable

Thank You