1 2 think about… 6.1 the process of human nutrition 6.2 the human digestive system 6.3 ingestion...

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1

2

Think about…

6.1 The process of human nutrition

6.2 The human digestive system

6.3 Ingestion of food

6.4 Movement of food along the alimentary canal

6.5 Digestion of food

6.6 Absorption of digested food

6.7 Assimilation of absorbed food

6.8 Egestion

Recall ‘Think about…’

Summary concept map

3

Weight loss surgery can help obese people lose weight

4

small bag created at the top of stomach

it connects directly to ileum

food bypasses larger stomach and duodenum

ileum

stomach

duodenum

5

1 What is the roleof the stomach

6

2 How does the surgery help peoplelose weight

7

3 What will happenif the food does notpass through the ileum also

8

2 digestion (消化 )

1 ingestion (攝食 )

6.1 The processes of human nutrition

complex and insoluble food molecules

food

simple and soluble food molecules

9

5 egestion (排遺 )

3 absorption (吸收 )

4 assimilation (同化 )

1 ingestion (攝食 )

6.1 The processes of human nutrition

digested food

faeces

2 digestion (消化 )

10

The five main processes of

and .

nutrition in humans are

absorptiondigestion

ingestion

egestionassimilation

, ,

6.1 The processes of human nutrition

11

6.2 The human digestive system

What does our digestive system

(消化系統 ) consist of?

12

6.2 The human digestive system

Digestive system

Alimentary canal(消化道 )

Glands(腺 )

13

Alimentary canal

1 mouth cavity

2 pharynx (咽 )

3 oesophagus (食道 )

4 stomach

6.2 The human digestive system

14

5 small intestineduodenum

ileum

6 large intestinecolon

rectum7 anus (肛門 )

Alimentary canal6.2 The human digestive system

15

Glands

pancreas (胰 )

liver

salivary glands

6.2 The human digestive system

16

its associated .glands

Our digestive system consists of the andalimentary canal

1

6.2 The human digestive system

17

oesophagus

anus

small intestine

stomach

mouth cavity

pharynx

large intestine

start

end

2 Alimentary canal:

6.2 The human digestive system

18

,

liver

pancreassalivary glands3 Associated glands:

,

6.2 The human digestive system

19

6.3 Ingestion of food

mouth cavity• food is taken in through the mouth

20

• mastication (咀嚼 ): chewing food into small pieces

teeth

6.3 Ingestion of food

21

1 Incisors (門齒 )

• for biting and cutting food

A) Types of teeth

chisel-shaped (鑿形的 )

flat sharp edges

one root

6.3 Ingestion of food

22

2 Canine (犬齒 )

• for tearing flesh

• well-developed in carnivores

one root

pointed and curved

A) Types of teeth6.3 Ingestion of food

23

3 Premolar (前臼齒 )

• for cutting and grinding food

A) Types of teeth

1 or 2 roots

broad top with cusps

6.3 Ingestion of food

24

4 Molar (臼齒 )

• similar to premolar but larger

A) Types of teeth

2 or 3 roots

6.3 Ingestion of food

25

B) Structure of a tooth

crown (齒冠 )

neck (齒頸 )

root (齒根 )

• divided into

6.3 Ingestion of food

26

1 Enamel (琺瑯質 )

• the outermost, hardest region

• protects teeth from wearing off

• non-living and is made mainly of calcium salt

6.3 Ingestion of food

27

1 Enamel (琺瑯質 )

• replaced by cement  (牙骨質 )

Around the roots…

• fibres from cement form periodontal membrane (牙周膜 )

periodontalmembrane

cement

6.3 Ingestion of food

28

2 Dentine (牙本質 )

• the middle region of the tooth

• contains strands of living cytoplasm

6.3 Ingestion of food

29

living cells

3 Pulp cavity (髓腔 )

nerve fibres

blood vessels

6.3 Ingestion of food

30

blood vessels

• detect temperature and pressure

• supply oxygen and nutrient

nerve fibres

• remove waste

3 Pulp cavity (髓腔 )

6.3 Ingestion of food

31

C) Dentition of humans

• represented by a dental formula (齒式 )

• dentition (齒系 ): number and arrangement of different types of teeth

6.3 Ingestion of food

32

C) Dentition of humans

2 incisors

1 canine

2 premolars

3 molars

• on each side of the upper jaw:

6.3 Ingestion of food

33

C) Dentition of humans

2 incisors

1 canine

2 premolars

3 molars

• on each side of the lower jaw:

6.3 Ingestion of food

34

C) Dentition of humans• dental formula of an adult:

21232123

i , c , pm , m 22

11

22

33

6.3 Ingestion of food

35

• appear during the first two years

21022102

• dental formula:

D) Milk teeth and permanent teeth

• first set of teeth:milk teeth (乳齒 )

6.3 Ingestion of food

36

D) Milk teeth and permanent teeth

• replace milk teeth between the ages of 6 and 12

• second set of teeth:permanent teeth (恆齒 )

• will not be replaced when lost

6.3 Ingestion of food

37

D) Milk teeth and permanent teeth

milk teeth

permanent teeth

6.3 Ingestion of food

38

and cut up by . The proces

s of chewing food into small piece

s is called

1 Food is put into the

mastication

mouth cavity

teeth

.

6.3 Ingestion of food

39

2 Match the functions of different types of teeth:

incisors canine

premolars

molars

biting and cutting

tearing flesh

crushing and grinding

6.3 Ingestion of food

40

root

neck

crown

3a Label the structure of the tooth.

6.3 Ingestion of food

41

pulp cavity

dentine

enamel

3b Label the structure of the tooth.

6.3 Ingestion of food

42

4a refers to the number and arrangement of different types of teeth in a mammal.

Dentition

It can be represented by a

.dental formula

6.3 Ingestion of food

43

4b Humans have two sets of teeth

in a lifetime:

i)

ii) permanent teeth

milk teeth

6.3 Ingestion of food

44

6.4 Movement of food along the alimentary canal

What will happen to us after

mastication?

45

1 Swallowing

Food is chewed

The tongue shapes the food into a

bolus

• before swallowing:

teeth

bolus (食團 )

tongue

Animation

6.4 Movement of food along the alimentary canal

46

• during swallowing:

1 Swallowing

1 The tongue pushes the bolus towards pharynx

6.4 Movement of food along the alimentary canal

47

• during swallowing:

1 Swallowing

2 The soft palate (軟腭 ) moves up to prevent the bolus from entering the nasal cavity

6.4 Movement of food along the alimentary canal

48

1 Swallowing• during swallowing:

3 The epiglottis (會厭 ) covers the trachea

4 The bolus enters the oesophagus

6.4 Movement of food along the alimentary canal

49

2 Peristalsis (蠕動 )

circular

muscle

(環肌 )

longitudinal muscle (縱肌 )

lumen (管腔 )

• rhythmic contraction and relaxation of the muscles

alimentary canal

6.4 Movement of food along the alimentary canal

50

circular muscles relax, longitudinal muscles contract

circular muscles contract, longitudinal muscles relax

food

food moved forward

2 Peristalsis (蠕動 )

6.4 Movement of food along the alimentary canal

51

1 Food is moved from the mouth cavity down the oesophagus by

the oesophagus towards the anus by .peristalsis

swallowing and down from

6.4 Movement of food along the alimentary canal

52

of the and

muscles in the wall of alimentary

canal. It causes the food to move

forward along the canal.

2 Peristalsis is the rhythmic

circular

contraction and relaxation

longitudinal

6.4 Movement of food along the alimentary canal

53

undigested food molecules

alimentary canal

blood

6.5 Digestion of food• undigested food is too large to pass

through the wallwall of alimentary canal

(differentially permeable)

54

digested food molecules

6.5 Digestion of food• digestion makes the food smaller,

simpler and soluble for absorption

alimentary canal

blood

55

Physical digestion (機械消化 )

smaller surface area larger surface area

• increases surface area for action of digestive juices (消化酶 )

physical action

• breaks down food into smaller pieces

food

6.5 Digestion of food

56

• examples:

1 Chewing by teeth

2 Churning (劇烈攪動 ) in the stomach

Physical digestion (機械消化 )

6.5 Digestion of food

57

4 Emulsification (乳化 ) by bile salts

lipidssmall droplets

3 Peristalsis along alimentary canal

Physical digestion (機械消化 )• examples:

6.5 Digestion of food

58

Chemical digestion (化學消化 )

digestive enzymes (消化酶 )

large, complex small, simple

• chemical reactions in which large, complex food molecules are broken down

6.5 Digestion of food

59

• three types of digestive enzymes

1 Carbohydrases (碳水化合酶 )

complex carbohydrates simpler sugars

e.g. amylase, sucrase and maltase

6.5 Digestion of food

60

2 Proteases (蛋白酶 )e.g. pepsin, trypsin and peptidases

protein

polypeptides

peptides amino acids

• three types of digestive enzymes

6.5 Digestion of food

61

3 Lipase (脂肪酶 )e.g. pancreatic lipase

fat fatty acids glycerol

• three types of digestive enzymes

6.5 Digestion of food

62

Digestion in mouth cavity• food is chewed into small pieces

and mixed with salivaAnimation

6.5 Digestion of food

63

salivary glands

Digestion in mouth cavity

• secreted by salivary glands

Saliva

• slightly alkaline

6.5 Digestion of food

64

Digestion in mouth cavity

i) salivary amylase

starch maltose

• consists ofSaliva

ii) mucus (黏液 )

- moistens and lubricates (潤滑 ) food

6.5 Digestion of food

65

Digestion in mouth cavity

• consists of

iii) water

- dissolves soluble substances in food

Saliva

6.5 Digestion of food

66

Digestion in stomach

oesophagus

Structure of the stomach

duodenum

muscle bag

6.5 Digestion of food

67

cardiac sphincter (賁門括約肌 )- closes the entrance

pyloric sphincter (幽門括約肌 )

- regulates the release of food into duodenum

Digestion in stomachStructure of the stomach

6.5 Digestion of food

68

stomach wall (450)

gastric glands inside pits

• gastric glands secrete gastric juice (胃液 )

Digestion in stomachStructure of the stomach

6.5 Digestion of food

69

Gastric juice

i) proteases• contains

protein peptides

Digestion in stomach6.5 Digestion of food

70

Digestion in stomachGastric juice

ii) hydrochloric acid- provides an acidic medium

for the action of proteases- kills most bacteria in food

• contains

HCl

bacteria

6.5 Digestion of food

71

Digestion in stomachGastric juice

iii) mucus- protects stomach from

being damaged by proteases and hydrochloric acid

• contains

proteases & HCl

mucus

6.5 Digestion of food

72

Digestion in stomach

churning & chemical digestion

food

called chyme (食糜 )

semi-solid paste

6.5 Digestion of food

73

• released to duodenum through bile duct (膽管 )

Digestion in small intestine

1 Bile• three digestive juices

• secreted by liver

• stored in gall bladder

6.5 Digestion of food

74

• released to duodenum through bile duct (膽管 )

• stored in gall bladder

• secreted by liver

Digestion in small intestine

1 Bile• three digestive juices

6.5 Digestion of food

75

Digestion in small intestine1 Bile• has no enzymes but containsi) bile salts

- emulsify lipids into small droplets

lipidslarger surface

areasmaller surface area

emulsification

6.5 Digestion of food

76

Digestion in small intestine1 Bile

iii) sodium hydrogencarbonate

ii) bile pigments

- neutralizes the acidic chyme

- give green colour to bile

- provides an alkaline medium for the actions of enzymes in duodenum

6.5 Digestion of food

77

Bile is produced by the gall bladder.

Digestion in small intestine1 Bile

6.5 Digestion of food

78

Bile is produced by the liver and temporarily stored in the gall bladder.

Digestion in small intestine1 Bile

6.5 Digestion of food

79

6.3

Investigation of the effect of bile salts on oil

1 Add 10 drops of bile salt solution to 1 cm3 of peanut oil.

peanut oil

bile salt solution

Animation

6.5 Digestion of food

80

6.3

2 Stopper the test tube and shake for 30 seconds. Observe the mixture and note any changes. shake

Results and discussion

An emulsion (乳狀物 ) is formed. This shows that bile salts can break down lipids into tiny droplets.

6.5 Digestion of food

81

• released to duodenum through pancreatic duct

Digestion in small intestine2 Pancreatic juice

• secreted by pancreas

• slightly alkaline

pancreas

pancreatic duct

6.5 Digestion of food

82

Digestion in small intestine2 Pancreatic juice

• contains:

i) pancreatic amylase

starch maltose

6.5 Digestion of food

83

Digestion in small intestine2 Pancreatic juice

• contains:

ii) protease

protein peptides

6.5 Digestion of food

84

Digestion in small intestine2 Pancreatic juice

• contains:

peptides amino acids

ii) protease

6.5 Digestion of food

85

Digestion in small intestine2 Pancreatic juice

• contains:

iii) lipase

lipid fatty acids glycerol

6.5 Digestion of food

86

Digestion in small intestine2 Pancreatic juice

• contains:

iv) sodium hydrogencarbonate- neutralizes the acidic chyme

- provides an alkaline medium for the actions of enzymes in duodenum

6.5 Digestion of food

87

Digestion in small intestine3 Intestinal juice

• secreted by the glands on the wall of the small intestine

ileum

duodenum

6.5 Digestion of food

88

Digestion in small intestine3 Intestinal juice

• contains mucus

• slightly alkaline

ileum

duodenum

• no enzymes

6.5 Digestion of food

89

Digestion in small intestine• some specialized cells on the wall also

involved in digestion

ileum

duodenum

specialized cells

6.5 Digestion of food

90

Digestion in small intestine• enzymes present on their cell membrane

enzymeshere

ileum

duodenum

6.5 Digestion of food

specialized cells

91

Digestion in small intestine• The enzymes include:

i) carbohydrases

disaccharides monosaccharides

6.5 Digestion of food

92

ii) proteases

Digestion in small intestine

peptides amino acids

• The enzymes include:

6.5 Digestion of food

93

Digestion in small intestine

• Digestion completed at the end of ileum

monosaccharides

amino acids

fatty acids

glycerol

ready for

absorption

6.5 Digestion of food

94

makes the food ,

and for absorption.

1 The food we take in is tooto pass through the wall of the

alimentary canal, which is

differentially permeable. Digestion

large

smaller simpler

soluble

6.5 Digestion of food

95

Physical digestion is mainly brought about by action of the teeth, in the stomach, along the alimentary canal, and

of lipids by bile salts.

peristalsis

churning

chewing2a

emulsification

6.5 Digestion of food

96

Physical digestion increases the of food for chemical digestion.

surface area

2b

6.5 Digestion of food

97

involves chemical reactions in which large, complex food molecules are broken down into smaller, simpler forms. The reactions are catalysed by .digestive enzymes

Chemical digestion3a

6.5 Digestion of food

98

Some digestive enzymes are

present in the

secreted by the .

3bdigestive juices

digestive glands

6.5 Digestion of food

99

4a Digestion of carbohydrates:Mouth cavity

starch maltosein

Duodenum

starch maltosepancreatic amylase

pancreatic juice

salivasalivary amylase

in

6.5 Digestion of food

100

carbohydrases

4a Digestion of carbohydrates:Small intestine

disaccharides monosaccharides

on the cell membranes of the specialized cells in the intestinal wall

6.5 Digestion of food

101

proteasesgastric juicein

pancreatic juiceproteases

in

4b Digestion of proteins:Stomach

protein

Duodenumprotein, peptides,

amino acidspeptides

peptides

6.5 Digestion of food

102

Small intestine

peptides amino acidson the cell membrane

of the specialized cells in the intestinal wall

proteases

6.5 Digestion of food

4b Digestion of proteins:

103

in

bile salt

bile

4c Digestion of lipids:Duodenum

lipidssmall droplets

lipidsfatty acids,glycerolpancreatic juice

lipasein

6.5 Digestion of food

104

6.6 Absorption of digested food

mainly takes place in ileum

105

• allows sufficient time for absorption

1 Long intestine

It’s 7m long!

Adaptation of small intestine for food absorption

6.6 Absorption of digested food

106

cross-section of small intestine

2 Highly-folded intestinal wall and numerous villi (絨毛 )

epithelium covered with villi

Adaptation of small intestine for food absorption

6.6 Absorption of digested food

107

inner surface of ileum

epithelium covered with villi

Adaptation of small intestine for food absorption

2 Highly-folded intestinal wall and numerous villi (絨毛 )

6.6 Absorption of digested food

108

Adaptive features of villi

• increases surface area for absorption

1 Finger-like projections

6.6 Absorption of digested food

109

• reduces the distance for diffusion of food molecules

Adaptive features of villi

2 Thin epithelium

6.6 Absorption of digested food

110

3 Presence of lacteal and a network of blood capillaries

• carry away the absorbed food molecules rapidly

Adaptive features of villi

blood capillary

lacteal

6.6 Absorption of digested food

111

4 Movement of villi caused by peristalsis

• keeps a steep concentration gradient of food molecules

Adaptive features of villi6.6 Absorption of digested food

112

monosaccharides

amino acids

water-soluble vitamins

active transport

diffusion

Absorption of digested foodInto the blood

minerals

Animation

6.6 Absorption of digested food

113

hepatic vein

hepatic portal vein all parts of

the body

Absorption of digested foodInto the blood

liver

6.6 Absorption of digested food

114

Absorption of digested foodInto the lymph

lumen epithelium lacteal

fatty acid

glycerol

fatty acid

glycerollipid lipid

6.6 Absorption of digested food

115

all parts of the body

lymph vessel

Absorption of digested foodInto the lymph

6.6 Absorption of digested food

116

Absorption of water

water

osmosis

blood capillary

• most water is absorbed in stomach and small intestine

6.6 Absorption of digested food

117

6.4

Simulation of digestion and absorption in the small intestine using dialysis tubing

1 Tie a knot at one end of a dialysis tubing. Fill the tubing with equal volumes of starch solution and amylase solution.

6.6 Absorption of digested food

118

6.4

2 Tie the other end of the tubing.

3 Immerse the tubing in water at 37°C.

dialysis tubing

water at 37oC

starch and amylase

6.6 Absorption of digested food

119

6.4

4 Test the water outside the tubing immediately for starch and reducing sugars using iodine solution and Benedict’s solution respectively. Perform the same tests after one hour.

6.6 Absorption of digested food

120

6.4

Results and discussion

• At the beginning of the experiment, neither starch nor reducing sugars are present in the water. However, reducing sugars are detected after one hour.

6.6 Absorption of digested food

121

6.4

Results and discussion

• These results show that amylase helps break down starch into reducing sugars and only the reducing sugar molecules are small enough to pass through the dialysis tubing.

6.6 Absorption of digested food

122

Absorption1 is the movement of

food molecules from the

alimentary canal into the

circulatory system. It takes place

mainly in the ileum.

6.6 Absorption of digested food

123

2a

Adaptation Significance

Increase surface area for

absorption

Highly-folded wall and nume

rous villi

How is the small intestine adapted for food absorption?

6.6 Absorption of digested food

124

Adaptation Significance

Reduces the distance for

diffusion of food molecules

Thin epithelium

2b How is the small intestine adapted for food absorption?

6.6 Absorption of digested food

125

Adaptation Significance

Carry away the absorbed food

molecules rapidly

2c

Presence of lacteal and a network of blood capillaries

How is the small intestine adapted for food absorption?

6.6 Absorption of digested food

126

Adaptation Significance

Keeps a steep concentration

gradient of food molecules

Movement of villi caused by peristalsi

s

2d How is the small intestine adapted for food absorption?

6.6 Absorption of digested food

127

diffusion and active transport. They are carried to the liver via the .

3a Monosaccharides, amino acids, minerals and water-soluble vitamins are absorbed into the

hepatic portal vein

blood capillaries of the villi by

6.6 Absorption of digested food

128

before entering the

.

3b Fatty acids and glycerol diffuse

into the epithelium of the villi.

Here they recombine to form

lacteals

lipids

6.6 Absorption of digested food

129

6.7 Assimilation of absorbed food

• the uptake and use of absorbed food molecules for metabolism

130

energyglucose

i) for releasing energy

The fate of absorbed food1 Glucose

respiration

6.7 Assimilation of absorbed food

131

ii) excess glucose is converted into glycogen or lipid in liver

glycogen

lipid

stored in

stored

liver / muscle

under skin / around internal organs

The fate of absorbed food1 Glucose

6.7 Assimilation of absorbed food

132

The fate of absorbed food2 Amino acidsi) for making proteins

ii) excess amino acids are deaminated in liver

proteins for growth

proteins for repair

enzymes

antibodies

hormones

6.7 Assimilation of absorbed food

133

The fate of absorbed food3 Lipidsi) as energy reserve

ii) for making cell membrane

iii) for protecting internal organs or reducing heat loss

subcutaneous fat

6.7 Assimilation of absorbed food

134

The roles of the liver

• blood glucose level > normal

glucoseliver

• blood glucose level < normal

glucoseliver

glycogen

glycogen

1 Regulate blood glucose level

6.7 Assimilation of absorbed food

135

• main site for storing glycogen

glycogen

2 Storage of glycogen, iron and fat-soluble vitamins

The roles of the liver6.7 Assimilation of absorbed food

136

• stores fat-soluble vitamins

vitamin A

vitamin D

2 Storage of glycogen, iron and fat-soluble vitamins

The roles of the liver6.7 Assimilation of absorbed food

137

• for storing iron from the breakdown of red blood cells

iron

2 Storage of glycogens, iron and fat-soluble vitamins

The roles of the liver

red blood cells

6.7 Assimilation of absorbed food

138

• secretes bile

• changes carotene to vitamin A

• produces heat

3 Production of bile, vitamin A and heat

The roles of the liver

metabolic activities

heat

6.7 Assimilation of absorbed food

139

4 Deamination

excess amino acids

ureaamino group

carbohydrates

lipids

remaining parts

The roles of the liver6.7 Assimilation of absorbed food

140

toxins

(e.g. alcohol,

drugs)

harmless

substances

The roles of the liver5 Detoxification (解毒 )

6.7 Assimilation of absorbed food

141

Assimilation1 is the uptake and

use of absorbed food molecules by cells for metabolism.

6.7 Assimilation of absorbed food

142

for making cell membrane

as energy reserve

for releasing energy

for making proteins

2 How are the absorbed food molecules assimilated inside cells? glucose

amino acids

lipids

6.7 Assimilation of absorbed food

143

• stores , and iron

blood glucose level

glycogen

fat-soluble vitamins

bile vitamin A

heat

• produces , and

• regulates3 The roles of the liver include:

6.7 Assimilation of absorbed food

144

• deaminates excess

• detoxifies mild toxins

amino acids

3 The roles of the liver include:

6.7 Assimilation of absorbed food

145

6.8 Egestion

• the process of expelling faeces (糞便 ) from the body

• faeces consist of

dietary fibre secretions from alimentary canal

bacteria dead cells

• also called defaecation (排糞 )

146

faeces stored in rectum temporarily

anal sphincter muscle relaxes and rectum muscle contracts to push the faeces out

6.8 Egestion

147

is the process of expelling Egestion

faeces from the body.

6.8 Egestion

148

1 What is the role of the stomach?• The stomach churns to break down

food into smaller pieces physically.

• It secretes proteases to chemically digest proteins.

• It also releases hydrochloric acid which kills most bacteria in food.

149

2 How does the surgery help people lose weight?

Without passing through the stomach and duodenum, the food cannot be fully digested. Therefore, fewer food molecules are absorbed by the body.

150

3 What will happen if the food does not pass through the ileum also?

It may result in malnutrition as most consumed food is undigested and the body cannot get enough nutrients for healthy growth.

151

Nutrition

ingestion

digestion

consists of

absorption

assimilation

egestion

occurs mainly in

villi

occurs in

body cells

152

involves

digestion

physical digestion

chemical digestion

brought about by

enzymes

153

physical digestion

brought about by

chewing by teeth

churning in stomach

emulsification of lipids by bile salts

peristalsis

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