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The Essential MicrotomeLeica RM2125 RTS Manual MicrotomeCut the high-quality sections that accurate diagnosis depends on. The Leica RM2125 RTS manual microtome has the essential features you need for safer economic sectioning and optimized workflows.

Quality is essentialWhen cutting sections from patient tissue, you want every section to count. The Leica RM2125 RTS utilizes the essential elements of proven Leica Microsystems’ technology to deliver high-quality sectioning in an economical manual package.

• Accuracy – precise feed mechanism means precise sections• Stability – PowerBase ensures stable operation for vibration-free sectioning• Security – advanced knife holder and specimen clamp securely align cutting edge to block

Safety is essentialBecause you don’t want to compromise on safety, the Leica RM2125 RTS doesn’t either. By combining the essential elements of intuitive operation and advanced safety features, the Leica RM2125 RTS helps microtomists work more safely throughout each shift.

• Only the essentials – with only the most important functions, complexity is reduced and operation simplified

• For the user – user-selectable coarse feed wheel turn direction and retraction functions so the microtome works for each individual user

• Added safety by design – a smooth running hand wheel, built-in safety guards and a rounded instrument shape with arm rests for fatigue-free sectioning

Productivity is essentialWith no time to waste, efficient sectioning is critical for overall laboratory productivity. The manual Leica RM2125 RTS has the essential features for highly productive sectioning.

• Efficient set up – a quick-exchange specimen clamp and an 8° orientation system for the object head allow rapid set up for any block

• Efficient operation – two trim steps (50 µm coarse, 10 µm fine) mean fast trimming so you can produce sections sooner

• Efficient use of space – store essential tools and accessories on top of the microtome so they are off the bench, and easy to access

Leica RM2125 RTS Technical Specifications

General Information

Section thickness setting range: 0.5 – 60 µm Total horizontal specimen feed: 25 mm Vertical specimen stroke: 59 mm Specimen retraction: ON/OFF Coarse feed wheel turn direction: User selectableSpecimen orientation: XY – 8° Trimming thickness: 10 µm, 50 µm

Dimensions

Dimensions (W x D x H): 438 mm x 472 mm x 265 mm,17.24” x 18.58” x 10.43”Weight: (without accessories): 29 kg, 63.9 lbs

Technical specifications subject to change. The Leica RM2125 RTS has been designed and manufactured in compliance with IEC requirements.

www.leica-microsystems.comOrder no.: English 1495.9977 • 95.9977 Rev A • Copyright © by Leica Biosystems Nussloch GmbH, Nussloch, Gemany, 2010 LEICA and the Leica Logo are registered trademarks of Leica Microsystems IR GmbH.

Leica RM2125 RTS with PowerBase stability

Quick-exchange specimen clamp

8° orientation system

Two trim steps for efficient operation

Leica RM2235The Manual Rotary Microtome For Outstanding Durability,Precision and Comfort

RM2235_en_Brochure_New.qxd:RM2235_en_Brochure_New.qxd 02.06.2009 10:15 Uhr Seite 1

As Durable as Ever, Enhanced Precision and ComfortLike Never Before: The New Leica RM2235

Durability is essential in a manual microtome and the

Leica RM2235 can stand up to the workload requirements

of even the busiest laboratories. The enhanced precision

of the new accessories will add convenience to block to

knife approach as well as specimen orientation.

The new Leica RM2235 manual microtome provides

unique user-friendliness, achieved through numerous new

features, most of them patented, which have never before

been offered in this class of microtome. The Leica RM2235

combines proven technology with well thought-out ergo-

nomic details and the highest safety standards.

Working in comfort is not a luxury but a necessity. A re-

laxed, ergonomic working posture is a basic prerequisite

for the high levels of speed, precision, and efficiency

required in modern laboratories. Day after day, the new

Leica RM2235 provides comfortable functionality without

compromise. The RM2235 is the instrument of choice for

all clinical histology and histopathology institutions where

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The New Approach to Manual Sectioning

� Fatigue-free operationErgonomics and user comfort wereprime considerations for the locationof the coarse feed wheel, which ispositioned close to the operator.The direction of the handwheel rota-tion to best suit your sectioning stylecan be specified at the time an orderis placed. The mechanical trimmingfunction, conveniently placed nextto the coarse feed wheel, eliminatesthe need to turn the coarse feedwheel during trimming.

� Spacious, magnetized section waste tray

The spacious section waste trayreliably collects sectioning debris.It is safely held in position bymagnets, yet is easily removable foremptying and cleaning.

� Convenient storage areaAn integrated storage tray* ensuresthat ancillary tools are on hand at alltimes. Alternatively a cooling plate withthermo element can be used for coldstorage of specimen blocks either ontop or on either side of the microtome.

Leica Design by Werner Hölbl

* not supplied with basic instrument

� Safety during sectioningSafety is ensured by the integrated,red finger protection guard of theknife holder E that uniquely shieldsthe blade edge. When used correctlythe integrated finger protection guardrules out potential injuries becauseit can even remain on the blade edgeduring sectioning.


� Fast sectioning without specimen orientationFor applications where specimen orientation is notneeded, a non-orienting fixture for specimen clampsis available as an optional accessory. The SuperMega cassette can clamp specimens up to a size of46 x 66 x 10 mm (W x H x D).

� Precision specimen orientation withclear zero reference point

This novel orientation mechanism sets new standardsof precision and is very easy to operate. Calibratedcontrols make it easy to adjust a specimen to an exactzero position indicated by red pins or a measurablevariable on the x/y axis for re-cuts.

� Lateral knife holder adjustmentThe entire width of the microtome blade can be usedwithout having to release the blade clamping mecha-nism. Using the entire knife edge is cost effective, espe-cially in laboratories with high specimen throughput.Three predefined stop positions (left, center, right)correspond to the width of a standard histology cassette.

� A special accessory: Chilled universal cassette clamp (UCC)

The UCC is kept cold by placing ice cubes or dry ice ina special compartment, which ensures that specimenblocks remain at cold temperatures throughout theentire sectioning process.

� Ergonomics and user safetyThe smooth-running safety handwheelhas an ergonomically shaped handle.A handwheel locking device for one-thumb operation locks the specimenhead in the uppermost position, whichis ideal for changing the specimenand/or blade. A second locking mecha-nism on the microtome base allowsthe object head to be locked in anyposition.

Well thought-out and proven:

• Knife holder baseuniversal knife holder base fits virtually all Leica knifeholder systems.

• Universal cassette clamp for single-hand operationdefinitely THE easiest way to clamp/remove specimens.

• Optimized microtome base plateprovides maximum rigidity – thanks to the latest technologyand new lightweight materials.

• One-piece housingmade from specially resistant plastic, without any edgeswhere debris could accumulate, which reduces cleaningto a minimum.

• Fewer clamping levers makes the Leica RM2235 easier to use by providing improvedaccess to the cutting area.

� The patented force balancingsystem

The RM2235 handwheel runs excep-tionally smoothly because it has nobalancing weight. Instead, the pa-tented force balancing system usesa spring to compensate the forcesgenerated during sectioning. Theresult: effortless operation and uni-form handwheel rotation – producingmuch better sectioning results.

Leica-patented:Spring-based forcebalancing system

Conventional:Handwheel withbalancing weight


Technical Specifications

The Leica RM2235 features at a glance:

• Precision specimen orientation with zero point reference

• Compact, ergonomic overall design

• User safety integrated into all aspects of the instrument

• Ergonomically located coarse feed wheel forfatigue-free operation

• Extremely smooth-running handwheel due topatented force compensation system

• Two safety locking mechanisms on the handwheel

• Precise knife holder lateral adjustment ensuresthat the entire width of the blade edge can be used

• Cooling plate (optional)

• Single-handed operation specimen clamps

• Universal knife holder base for different knife holders

• Disposable blade holder with integrated safetyfinger protection guard

• Spacious magnetized section waste tray

• One-piece, easy-to-clean housing

Section thickness

• Setting range: 1 – 60 µm• Setting values: 1 – 10 µm in 1 µm increments

10 – 20 µm in 2 µm increments20 – 60 µm in 5 µm increments

Section thickness indication: viewing window

Coarse feed: manual via coarse feed wheel

Trim settings: 10, 30 µm

Total horizontal specimen feed: approx. 30 mm

Vertical stroke: 70 mm

Specimen retraction: approx. 60 µm, can be deactivated

Maximum specimen size (W x H x D): 50 x 66 x 30 mm

Specimen orientation: horizontal: 8°vertical: 8°

Dimensions

• Width (including handwheel): 413 mm (16.26 in.)

• Depth (including section waste tray): 618 mm (24.33 in.)

• Height (with storage tray installed on housing): 305 mm (12.01 in.)

• Weight (without accessories): approx. 34 kg, 75 lbs

A wide range of accessories is available upon request.Technical specifications are subject to change without notice.Certifications: CE, c-CSA-us

Up-to-date development, production and quality control procedures are certified under DINEN ISO 9001 to ensure highest quality and reliability.


Leica RM2245The Manual Microtome with High-Precision Motorized Specimen Feed


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The New Leica RM2245 – EfficiencyGoes Hand in Hand with Comfort

The new Leica RM2245 semi-motorized rotary microtome

represents the perfect combination of economic efficiency

and user comfort. It is the instrument of choice for clinical

histology and histopathology applications, as well as for

industrial quality assurance.

The Leica RM2245 is designed to meet the many require-

ments of modern laboratories. This task is fulfilled without

compromise by combining proven technology and exem-

plary safety standards with functionality and ergonomic

design.

Manual sectioning is enhanced by the high-precision moto-

rized specimen feed, which results in efficient operation

with maximum section reproducibility. Operator fatigue is

reduced through the use of the patented spring system,

which eliminates the need for a heavy counter balance

weight in the handwheel. Enhanced user comfort results

in maximum workplace efficiency and high specimen

throughput.

With the Leica RM2245 there is a choice between the

conventional manual sectioning method of full handwheel

rotation and the “rocking mode”. In rocking mode, the

handwheel is only turned back and forth over a short dis-

tance. Every change in rotation direction is automatically

translated into a specimen feed or retraction movement.


The Useful Details Show a Great Design Concept

�

DLsTdm

� Safety during sectioningSafety is ensured by the integrated,red finger protection guard of theknife holder E that uniquely shieldsthe blade edge. When used correctlythe integrated finger protectionguard rules out potential injuriesbecause it can even remain on theblade edge during sectioning.

� Unobstructed work areaTo provide improved access to thecutting area, several clamping leversthat are not routinely used havebeen replaced by hidden clampingdevices without compromising stan-dard setting options.

� Convenient storage areaAn integrated storage tray* ensuresthat ancillary tools are on hand at alltimes. Alternatively a cooling platewith thermo element can be usedfor cold storage of specimen blockseither on top or on either side of themicrotome.

� Comfortable operationAll functions are controlled via a com-pact, space-saving control panel withareas in contrasting colors and touch-sensitive buttons that allow ‘blindoperation‘. Panel inclination is adjus-table, and the panel can be positionedeither on the left or right side of theinstrument.

Leica Design by Werner Hölbl * not supplied with basic instrument


� Precision specimen orientation withclear zero reference point

This novel orientation mechanism sets new standards of preci-sion and is very easy to operate. An important detail: Calibratedcontrols make it easy to adjust a specimen to an exact zeroposition indicated by red pins or a measurable variable on thex/y axis for re-cuts.

� Lateral knife holder adjustmentThe entire width of the microtome blade can be used withouthaving to release the blade clamping mechanism. Using theentire knife edge saves costs, especially in laboratories withhigh specimen throughput. Three predefined stop positions(left, center, right) correspond to the width of a standard histo-logy cassette.

� Ergonomics and user safetyThe smooth-running safety hand-wheel has an ergonomically shapedhandle. A hand-wheel locking devicefor one-thumb operation locks thespecimen head in the uppermostposition, which is ideal for changingthe specimen and/or blade. A secondlocking mechanism on the microtomebase allows locking the object headin any position.

Well thought-out and proven

• The Leica-patented Force Compensation Systemfor extremely smooth manual handwheel operation.

• The Precision Micrometer Feed Systemfrom 0.5 µm to 100 µm in sectioning mode and 1 µm to600 µm in trimming mode via stepper motor.

• The Leica Control Panel Conceptseparate and intuitive control panel for instrumentsettings and communication display integrated in theinstrument housing at eye level.

• Accessoriesa wide range of blade or knife holders and specimenholders is available for a variety of applications.

� Easy to cleanDue to the rounded shape of theLeica RM2245’s one piece housing,section waste is easily removed.The integrated slot cover preventsdebris from entering the internalmechanisms of the microtome.

� Spacious, magnetized sectionwaste tray

The spacious section waste tray re-liably collects sectioning debris. It issafely held in position by magnets,yet is easily removable for emptyingand cleaning.

� StabilityMaximum rigidity and stability areprovided by the optimized microtomebase plate.


The Leica RM2245 features at a glance:• Precision specimen orientation with zero point reference


• Section thickness totalizer and section counter

• Easy alternation between trimming and sectioning function

• Two motorized forward and backward specimencoarse feed speeds

• Programmable specimen retraction

• Low-maintenance cross roller bearings

• Single-handed operation universal cassette clamp

• Completely new knife holder concept for disposableblades, with finger guard in contrasting color

• Precise knife holder lateral movement

• User safety integrated into overall design

• Smooth-running handwheel with integratedquick-lock mechanism

• Ergonomically optimized handwheel handle

• Communication display integrated in instrument housing

• Enclosed micrometer mechanism

• Spacious magnetized section waste tray

• Intuitive control panel

• Wide range of accessories

Section thickness

• Setting range: 0.5 – 100 µm• Setting values: from 0.5 – 5 µm in 0.5 µm-increments

from 5 – 20 µm in 1 µm-incrementsfrom 20 – 60 µm in 5 µm-incrementsfrom 60 –100 µm in 10 µm-increments

• Trimming sectionthickness setting range: 1 – 600 µm

• Setting values: from 1 – 10 µm in 1 µm-incrementsfrom 10 – 20 µm in 2 µm-incrementsfrom 20 – 50 µm in 5 µm-incrementsfrom 50 – 100 µm in 10 µm-incrementsfrom 100 – 600 µm in 50 µm-increments

Object feed: 28 mm ±1 mm, feed motionvia step motor

Vertical specimen stroke: 70 mm

Sectioning modes: 2 manual modes (conventional fullhandwheel rotation and rocking mode)

Specimen retraction: 5 – 100 µm in 5 µm-increments,can be turned off

Electric coarse feed: 300 µm/s and 900 µm/s

Maximum specimen size (L x H x W): 50 x 60 x 40 mm

Specimen orientation: horizontal: 8°, vertical: 8°

Nominal supply voltages: 100/120/230/240 V AC ±10%

Nominal frequency: 50/60 Hz

Power draw: 70 VA

Dimensions basic instrument• Width (including handwheel): 413 mm• Depth (including waste tray): 618 mm• Height (with storage area on cover): 305 mm • Weight (without accessories): approx. 37 kg (87 lbs)

Dimensions control panel• W x D x H: 94 x 164 x 50 mm• Weight: approx. 0.450 kg (1 lb)

Wide range of accessories on request.Technical specification subject to change.Certificates: CE, c-CSA-us

Up-to-date development, production and quality control procedures certifiedunder DIN EN ISO 9001 to ensure highest quality and reliability.



Leica RM2255Rotary Microtome for high-Performance Motorized andManual Sectioning


The New Leica RM2255 Rotary Microtome

High-performance is an important factor when considering

the quality of rotary microtomes. A modern microtome

must also offer safety, ergonomy, efficiency, and economy.

With this in mind, Leica Microsystems designs and

manufactures microtomes that set new standards in

today’s laboratory.

The new fully automated Leica RM2255 microtome embodies

the latest technological innovations in microtomy and per-

fectly harmonizes practical features with an ergonomic

design and user safety. Its two-in-one design concept,

which allows motorized as well as manual sectioning,

provides reproducible, quality sections.

The Leica RM2255 is a blend of proven high-performance,

precision microtome technology with all the added bene-

fits customers expect from the market leader in microtomy.

The attention to detail in this new microtome, part of the

Leica RM2200 family of quality microtomes, represents

another step in the advancement of innovative, user-

oriented microtomes.


High-Performance Motorized an

� Oncomband practThe speccomffast a

� Knife holder E is our most popular knife holder andaccepts either high or low profiledisposable blades. For enhancedsafety, an integrated finger guardcovers the entire blade, even duringsectioning.

� Sw

conpartraymathecle

� Ample storage space:on an integrated storage tray providesplenty of space for your ancillary tools.For cool storage of specimen blocksright on the microtome, we recommendthe optional cooling tray with uniquecooling blocks.

� Fewer clamping levers permit unencumbered access to thecutting area. The locking pins canalso be moved from one side to theother and the levers can be reposi-tioned after locking to further clearthe work area.

� Control panelwith colored, raised keys, allows‘touch’ control so all of the opera-tor’s attention can be fully focusedon sectioning and section retrieval.The panel has adjustable inclination,a very small footprint, and can bepositioned to the left or right of theinstrument.



� Precise specimen orientation sets new standards of precision in rotary microtomes. With theuse of calibrated controls and visual aids, it is simple to adjustthe specimen to an exact zero point or in measurable variablesof up to 8° along the x-y axis.

� Lateral knife holder adjustmentallows the use of the entire length of the blade without having tochange the tension setting. Three predefined stop positions (left,center, right) that correspond to the width of a standard histologycassette may be used if desired.

Proven Technology:

• Leica’s patented gravitational forcecompensation system

makes rotating the handwheel extremely smooth andlight, which is especially beneficial during manualsectioning applications.

• Precise micrometer feed system permits precision sectioning from 0.5 µm to 100 µmvia the use of a stepper motor and low-maintenance,cross-roller bearings.

• Powerful sectioning motor is rugged enough for sectioning most hard specimenswithout producing sectioning artifacts.

• Specially designed electronics systemallows flexible operation of the instrument whileproviding precision control over the specimenadvance and cutting speeds.

• Universal knife holder baseis compatible with all routine Leica RM2200 seriesmicrotome knife holder systems that require a base.

• One-hand operated universal cassette clampis definitely THE easiest way to clamp and removespecimens.

and Manual Sectioning Sets New Standards!

� One-piece housing, combines ergonomics, aestheticsand ease-of-use while meeting thepractical requirements of the lab.The one-piece housing, made fromspecially resistant plastic, allowscomfortable access to controls andfast and easy cleaning.

� Spacious, integrated sectionwaste tray

conveniently prevents scattering ofparaffin debris. The section wastetray is securely held in position by amagnet, but is easy to remove fromthe instrument for emptying andcleaning.

� Stable microtome base platewas designed using the latest tech-nology and materials to produce arobust, stable, yet lightweight sup-port for the precision microtomemechanisms.

� Safe, smooth-running handwheelfeatures a new ergonomic handle, atraditional lock that locks anywherein the rotation, and a new easyaccess, quick-lock device to lock thespecimen in the uppermost position.For motorized sectioning, the hand-wheel handle can be centered.Safety is Leica’s number one priority.



• One-hand operated universal cassette clamp

• Completely new knife holder design with red coloredknife guard

• Precise lateral knife holder adjustment with click stopsettings

• Spacious and easy-to-clean section waste tray

• Wide range of accessories

• Compact, ergonomic design

• Ergonomically designed handwheel handle

• Smooth-running handwheel with integrated quick-lockmechanism for safety

• Enclosed micrometer feed mechanism

• Low-maintenance cross-roller bearings

• Two forward and backward coarse feed speeds

• Alternate trimming and sectioning modes, as indicatedon the display

• Speed control through the cutting window for enhancedefficiency

• Automatic, variable specimen retraction, depending onsectioning speed



• Integrated communication display

• Precise specimen orientation with zero point reference

The Leica RM2255 Features at a Glance:

Section thickness:Section thickness setting range: 0,5 – 100 µmSetting values: from 0,5 µm – 5 µm in 0,5 µm-increments

from 5 – 20 µm in 1 µm-incrementsfrom 20 – 60 µm in 5 µm-incrementsfrom 60 –100 µm in 10 µm-increments

Trimming sectionthickness setting range: 1 – 600 µmSetting values: from 1 – 10 µm in 1 µm-increments

from 10 – 20 µm in 2 µm-incrementsfrom 20 – 50 µm in 5 µm-incrementsfrom 50 – 100 µm in 10 µm-incrementsfrom 100 – 600 µm in 50 µm-increments

Object feed: 28 mm ±1 mm, feed motion via step motor

Vertical specimen stroke: 70 mm

Sectioning modes: 4

Specimen retraction:in manual operation: 5 – 100 µm in 5 µm-increments,

can be turned offin motorized operation: varying with the sectioning

speed, can be turned offElectric coarse feed: 300 µm/s und 900 µm/sSectioning speed: 0,5 – 420 mm/s ± 10%

Maximum specimen size (L x H x W): 50 x 60 x 40 mm

Specimen orientation: horizontal: 8°, vertical: 8°

Nominal supply voltages: 100 / 120 / 230 / 240 V AC ±10%

Nominal frequency: 50/60 Hz

Power draw: 340 VA

Dimensions basic instrument

Width (including hand wheel) 413 mm

Depth (including waste tray) 618 mm

Height (with storage area on cover): 305 mm

Weight (without accessories) approx. 37 kg, approx. 81 lbs

Dimensions control panel

WxDxH: 121 x 166 x 50 mm

Weight: approx. 0.66 kg, approx. 1.45 lbs

Wide range of accessories on request.Technical specification subject to change.Certificates: CE, c-CSA-us

Up-to-date development, production and quality control procedures certifiedunder DIN EN ISO 9001 ensure highest quality and reliability.


Leica RM2265The Fully Motorized, Programmable Rotary Microtome

Versatility Without Compromise:The Leica RM2265

When it comes to selecting a microtome, many factorshave to be taken into consideration and it's hard to decidewhich factor is the most important: reliability, innovativetechnology, efficiency, ergonomics or safety. Leicabelieves that each of these aspects is equally essential forthe most crucial requirement a modern microtome has tomeet: Versatility.

Leica Microsystems offers a microtome that can satisfyall of your laboratory’s requirements: the fully motorized,versatile Leica RM2265 rotary microtome. It is the top-of-the-line product in the Leica RM2200 rotary microtomeseries and is designed to produce superior sections of amultitude of specimen types with ease. Its outstandingtechnology allows it to be used for semi-thin to thick sec-tioning of soft or hard specimens; routine as well as spe-cial biomedical research applications; and industrial qual-ity assurance and materials research applications.Whether your instrument requirements are dedicated to asingle discipline or demand the versatility to perform in mul-tiple disciplines, the Leica RM2265 provides the perfectsolution for achieving constant, high-performance work-flow in your laboratory. And instead of compromising oneadvantage for another, the Leica RM2265 allows you to ben-efit from all of the latest state-of-the-art-technology in mod-ern microtomy.

With the Leica RM2265, a total of six sectioning modes areis available. In motorized operation there are four operat-ing mode selections: continuous, single or step stroke, andprogram mode. In manual operation it is possible to usethe conventional method of completing a full handwheelrotation or the intuitive “rock” mode. When the handwheelis moved back and forth over a small distance, eachchange in direction is electronically detected and auto-matically converted into an advance or retraction move-ment of the specimen arm.

A Sophisticated Approach to Versatility


■ Control panel operation The automated functions of themicrotome are controlled via a sep-arate, compact control panel. Con-trols for specific functions aregrouped together and the most usedareas contain contrasting colorsand touch-sensitive buttons thatallow “blind operation”. Panel incli-nation is adjustable, and the panelcan be positioned either on the leftor right side of the instrument.

■ Unobstructed work areaTo provide improved access to thecutting area, hidden clampingmechanisms have replaced severalclamping levers that are not rou-tinely used, without compromisingthe standard setting options.

■ Utmost versatility for manyspecial requirements

A wide choice of optional acces-sories includes a microscope carrierwith two fiber optic light guides forthe optimal illumination of the knifeand specimen.

■ Easy-to-cleanDue to the rounded shaLeica RM2265’s one-piecesection waste is easily The integrated slot coverdebris from entering thmechanisms of the microt

■ Precise specimen orientation with clear zeroreference point

This novel orientation mechanism sets new stan-dards of precision. Guided by visual indicators, theadjustment of calibrated controls makes it easy toorient a specimen to an exact zero position or to ameasurable variable on the x/y axis.

■ Universal knife holder baseThe knife holder base is suitable for holding variousdisposable blade or reusable knife holders, makingit possible to section a variety of specimen types.

■ Leica LN22 freezing deviceThe low temperature sectioning system has beenspecifically designed for use with the Leica RM2265microtome. Even the most demanding specimen canbe precisely sectioned in a thickness range from0.25 µm to 100 µm at temperatures down to –150 °C.

Well thought-out and proven

• Leica-Patented Force Compensation Systemprovides extremely smooth manual handwheel operation.

• Precision Micrometer Feed Systemprovides semi-thin to thick sectioning via stepper motor from0.25 µm to 100 µm in sectioning mode and 1 µm – 600 µm intrimming mode.

• Integrated, Intuitive Displayconveniently displays instrument settings and performanceinformation at eye level.

• Wide Range of Accessoriestailors the Leica RM2265 to meet individual needs and opti-mizes the sectioning performance of any specimen, e.g., awide assortment of holders for any type of knife or dispos-able blade and specimens of every shape; stereomicros-cope carrier; widefield magnifier; or Leica LN22 liquidnitrogen freezing device.

ape of thee housing,

removed.r preventse internaltome.

■ Ergonomics and user safetyThe smooth-running safety hand-wheel has an ergonomicallyshaped handle. A handwheel lock-ing device for one-thumb operationlocks the specimen arm in theuppermost position, which is idealfor changing the specimen and/orblade. A second locking mecha-nism on the microtome base allowslocking the object head in any posi-tion. During motorized sectioning,activation of the emergency stopbutton located on the instrumentwill immediately halt the movementof the specimen arm.

■ StabilityThe optimized microtome baseplate provides maximum rigidityand stability.

■ Magnetized section waste trayThe section waste tray is safely heldin position by magnets, yet is easilyremovable for emptying and clean-ing. If needed, a larger waste tray isoptionally available for applicationswith a high amount of sectioningdebris.

Leica RM2265 – Technical Specifications

The Leica RM2265 features at a glance:


• User safety integrated into the microtome andaccessories


• Automatic, variable specimen retraction, dependingon sectioning speed

• Two motorized forward and backward specimencoarse feed speeds

• Two separate programs for trimming andsectioning mode

• Speed control through the cutting window forenhanced efficiency

• Programmable vertical object head stop position,especially ideal for the LN22

• Communication display integrated in instrument housing

• Section thickness setting of 0.25 µm to 100 µm


• Smooth-running handwheel with integratedquick-lock mechanism

• Ergonomically optimized handwheel handle

• Low-maintenance cross roller bearings

• Enclosed micrometer mechanism

• Precision specimen orientation with zero pointreference

• Magnetized section waste tray

• Wide range of accessories for special applications

Section thickness:

• Section thicknesssetting range: 0.25 µm – 100 µm

• Setting values: 0.25 µmfrom 0.5 – 5.0 µm in 0.5 µm incrementsfrom 5 – 20 µm in 1 µm incrementsfrom 20 – 60 µm in 5 µm incrementsfrom 60 – 100 µm in 10 µm increments

• Trimming section thicknesssetting range: 1 – 600 µm

• Setting values: from 1 – 10 µm in 1 µm incrementsfrom 10 – 20 µm in 2 µm incrementsfrom 20 – 50 µm in 5 µm incrementsfrom 50 – 100 µm in 10 µm incrementsfrom 100 – 600 µm in 50 µm increments

Specimen retraction:

• Manual Operation programmable from 5 – 100 µm in 5 µmincrements; can be turned off

• Motorized Operation: varying with the sectioning speed;can be turned off

Electronic coarse feed: 300 µm/s or 900 µm/sSectioning speed range: 0.5 – 420 mm/sHorizontal specimen feed: approx. 30 mm

Vertical specimen stroke: 70 mmSectioning modes: 6 total

2 manual modes (regular and rocking mode) 4 motorized modes (continuous, single or step stroke,and program mode)

Maximum specimen size (L x H x W): 50 x 60 x 40 mm (1.96 x 2.36 x 1.57 in.)Specimen orientation: horizontal: 8°, vertical: 8°Power draw max: 340 VA

• Nominal supply voltages: 100 V / 120 V / 230 V / 240 V

• Nominal frequency: 50/60 Hz

Dimensions basic instrument

• (L x W x H): 563 x 413 x 305 mm (22.16 x 16.25 x 12 in.)(without magnifier or microscopecarrier)

• Weight (without accessories) approx. 37 kg (approx. 81 lbs)Dimensions control panel

• (W x D x H): 121 x 166 x 50 mm (4.76 x 6.53 x 1.96 in.)

• Weight: approx. 0.68 kg (approx. 1.45 lbs)

Wide range of accessories on request. Technical specification subject to change.Certificates: CE, c-CSA-us

Up-to-date development, production, and quality control procedures certified underDIN EN ISO 9001 to ensure the highest quality and reliability.

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