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Windows to Our Body features images created by faculty, trainees and staff of the Translational and Molecular Imaging Institute at the Icahn School of Medicine at Mount Sinai, and showcases how the state-of-the-art in medical imaging can, not only peer into the body with unprecedented precision, but reveal dynamic and captivating patterns and symmetry in the process.

If you have an interest in making a donation through the purchase of any of these images, please contact Christopher Cannistraci: [email protected]

For further information, please visit the Translational and Molecular Imaging Institute: tmii.mssm.edu

Translational and Molecular Imaging Institute

Our mission is centered around development, validation, translation and educa-

tion of innovative technology in biomedical imaging to address both basic and

clinical research problems and therefore improve human health.

The Translational and Molecular Imaging Institute serves as a research catalyst

for a new generation of translational and molecular imaging methodologies.

All images are Archival Inkjet Prints.

Minimum donation of $150.00 per image (unframed)

If you have an interest in making a donation through the purchase of any of these images,

please contact Christopher Cannistraci at [email protected]

#TMIInyc

List of Works

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Rebecca Feldman, PhD Balchandani Lab

Moments and Movement - 7T MRI, T2 TSE, Cerebellum, Coronol Oblique

Coordination is finding the right moments for your movement. This image of thecerebellum has been rotated and repeated.

Sarayu RamachandranMani Lab

Triptych - Computed Tomography of the Head and Chest

Surface rendering of lungs, heart and liver created in OsiriX.

Sarayu Ramachandran, MSMani Lab

Red Rivers - Magnetic Resonance(MR) Imaging or the Lower Extremities

Contrast-enhanced MR venography depicting vasculature in thighs

Rebecca Feldman, Ph.D.Balchandani Lab

Swippy - 7T MRI Axial Susceptibility weighted image of the human brain

Susceptibility weighted images are particularly good at imaging blood vessels in the brain.In this image the blood vessels in the brain are bright white, surrounded by a riot of colours in the rest of the brain tissue.

List of Works

Rebecca Feldman, Ph.D.Balchandani Lab

The Heart of the Brain - 7T MRI, T2 TSE, Brain

T2-weighted images of the brain presented with custom colour maps highlighting the contours of the cortex

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Rebecca Feldman, Ph.D.Balchandani Lab

Teuthida Vision - 7T MRI Coronal oblique T2 TSE human head

These images slice through the eyes, capturing just a hint of brain tissue to create the impression of an animal with large eyes and a tiny brain.

Bei Zhang, PhDBalchandani Lab

7T rabbit coil in CT scanner - 7T rabbit coil for MRI system

This is an image of components, conductive wires, cable traps of a 7T rabbit coil in CT system, and these details usually invisible in MRI system.

Paul Kennedy, PhDTaouli Lab

Ripple Effect - MR elastography of healthy and cirrhotic liver

Wave images and elastograms of healthy and cirrhotic liver showing increased wavelength in cirrhotic patient leading to elevated liver and spleen stiffness.

Alan C. Seifert, PhDXu Lab

Blowback - 7 T MRI, Human Brainstem and Cervical Spinal Cord

A sagittal slice through the brainstem and cervical spinal cord, acquired using a gradi-ent-echo pulse sequence and custom 22-channel brainstem and cervical spinal cord RF coil at 7 T.

List of Works

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14. Francesco Padormo, PhDBalchandani Lab

Phased Array - MRI of Spherical Marcol Oil Phantom

Each individual image displays the phase of a balanced steady state free precession acquisi-tion. The ‘bands’ are present due to the chemical composition of the phantom and by intentionally perturbing the shape of the magnetic field.

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Alan C. Seifert, PhDXu Lab

Brainstem in 6 Shades - 7T Multi-Echo GRE MRI of the Human Brainstem

This image contains 9 axial slices at 0.3 mm in-plane resolution through the human brainstem. The images are a root-sum-of-squares combination of four echo times, colorized in the "6 shades" colormap on one half of each frame, and overlaid with anoutline from Duvernoy's atlas on the other half.

Alan C. Seifert, PhD (arranged by Rebecca Feldman, Ph.D)Xu Lab

Midbrain Flowers - 7T Multi-Echo GRE MRI of the Human Midbrain

This image is created from a single axial slice at 0.3 mm in-plane resolution through the human midbrain at approximately the level of the substantia nigra and periaqueductal gray. The image is a root-sum-of-squares combination of four echo times, and is tiled in multiple colormaps to create the appearance of flowers.

Rebecca Feldman, Ph.D.Balchandani Lab

What’s Left Behind - 7T MRI, T2 TSE, Brain

Axial T2 TSE slices through the human brain, capturing the eyes and cortex with exquisite resolution.

Jun Tang, PhDMulder Lab (formally)

Nanoparticle Accumulation in Mouse Aortic Roots - Fluorescence microscopy of mouse aortic roots.

This picture shows that high-density lipoprotein (HDL)-based nanoparticles (red) efficiently target macrophages, the pathological immune cells in atherosclerosis, in aortic roots.

List of Works

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14. Francesco Padormo, PhDBalchandani Lab

Phased Array - MRI of Spherical Marcol Oil Phantom

Each individual image displays the phase of a balanced steady state free precession acquisi-tion. The ‘bands’ are present due to the chemical composition of the phantom and by intentionally perturbing the shape of the magnetic field.

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Alan C. Seifert, PhDXu Lab

Brainstem in 6 Shades - 7T Multi-Echo GRE MRI of the Human Brainstem

This image contains 9 axial slices at 0.3 mm in-plane resolution through the human brainstem. The images are a root-sum-of-squares combination of four echo times, colorized in the "6 shades" colormap on one half of each frame, and overlaid with anoutline from Duvernoy's atlas on the other half.

Alan C. Seifert, PhD (arranged by Rebecca Feldman, Ph.D)Xu Lab

Midbrain Flowers - 7T Multi-Echo GRE MRI of the Human Midbrain

This image is created from a single axial slice at 0.3 mm in-plane resolution through the human midbrain at approximately the level of the substantia nigra and periaqueductal gray. The image is a root-sum-of-squares combination of four echo times, and is tiled in multiple colormaps to create the appearance of flowers.

Rebecca Feldman, Ph.D.Balchandani Lab

What’s Left Behind - 7T MRI, T2 TSE, Brain

Axial T2 TSE slices through the human brain, capturing the eyes and cortex with exquisite resolution.

Jun Tang, PhDMulder Lab (formally)

Nanoparticle Accumulation in Mouse Aortic Roots - Fluorescence microscopy of mouse aortic roots.

This picture shows that high-density lipoprotein (HDL)-based nanoparticles (red) efficiently target macrophages, the pathological immune cells in atherosclerosis, in aortic roots.

List of Works

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20. Roey TsemahIndependant Artist

Willem.2014 - Digital woodcut (in its original form)

In this work, Roey brings the ancient technique of woodcut into the digital age. An ensemble of digitally chiselled elements were brought together into a single diagram illustrating a comprehensive portrait.

Hardien Dyvorne, PhD and Rebecca Feldman, PhD Balchandani Lab

Sampa Blanket - Matlab Simulation of a SAMPA RF pulse, Spatial spectral Excitation Profile

When we design the pulse sequences we use to acquire images in MRI, we have to make sure that we are selecting the region we’re interested in, and that we’re doing it as evenly as possible. Sometimes we fail at making things homogenous, but nothing is a complete failure.

Artist’s Biography

I'm a physicist who likes to hack MRIs, from hardware to sequences and imaging.

and olives but favours the Canadian ‘U’, the phrase ‘fair dinkum’, and Oxford commas. Rebecca was born in Australia, has lived in the United States and Canada, and works at the Translational and Molecular Imaging Insti-tute at the Icahn School of Medicine at Mount Sinai in New York City.

Dr. Rebecca Feldman was first introduced to image processing techniques in Matlab in Dr. Aaron Fenster’s lab at the Robart’s Research Institute (London, Ontario). She went on to obtain her BASC (Engineering Science – Electrical Option, 2003) from the University of Toronto and both her MSc (Medical Biophysics, 2005) and PhD (Medical Biophysics 2010) from the University of Western Ontario. She is now part of Dr. Balchandani’s High Field Magnetic Resonance Imaging Laboratory.

Rebecca’s work is the result of magnetic resonance imaging acquisitions and computer simulations processed and artificially coloured in Matlab, then finished and manipulated in GIMP. Her work has been inflicted on scientists and students as the cover art for Martin Zinke-Allmang’s Physics for the Life Sciences (4th Edition, 2006), in calendars compilations of MRI-based art (University of Alberta -2012, Translational and Molecular Imaging Institute – 2014, 2015, 2016), and as part of the Great Italian Art and Food Challenge at the ISMRM Annual Meeting (Italy, 2014). She has an aversion to pickles, optometrists,

Rebecca Feldman, PhD

Hadrien Dyvorne,, PhD

Paul completed his undergraduate and MSc studies in Dublin, Ireland before travelling to Edinburgh, Scotland to undertake his PhD in MR elastography. Having seen enough kilts to last a lifetime, Paul joined TMII in April 2016 as a postdoc in the Taouli lab. His work is focused on noninvasive measurement of organ mechani-cal properties, specifically the liver and kidneys. A supremely untalented artist, this is Paul’s first exhibition.

Paul Kennedy, PhD

joint Diploma as well as his PhD in Electrical and Computer Engineering in 2005 and 2010, respectively, from the National Technical University of Athens, Greece. His PhD thesis was on the optimization of preclinical and clinical PET imaging systems performance and data acquisition protocols using Monte Carlo simulations. He has co-au-thored more than 20 articles in international refereed journals and over 65 articles in peer-reviewed conference proceedings. He is a senior member of the Institute of Electrical and Electronic Engineers (IEEE) where he is primar-ily enrolled in the professional development activities of the IEEE Nuclear Plasma and Sciences (NPSS) society. Furthermore, he is a member of the Nuclear Medicine and Molecular Imaging (SNMMI) organization where he has recently been elected as the 2017-2019 Intern of the Computer and Instrumentation Council (CaIC). Dr. Karakatsanis has been certified by the American Board of Science in Nuclear Medicine (ABSNM) with a specialization in Nuclear Medicine Physics and Instrumentation.

Nicolas A. Karakatsanis, PhD

Dr. Nicolas (Nikolaos) A. Karakatsanis is currently a postdoctor-al research scientist at the Translational and Molecular Imaging Institute at Icahn School of Medicine at Mount Sinai Hospital in New York, NY, USA. His current interests focus mainly on truly quantitative PET/MR and PET/CT imaging utilizing advanced PET tracer kinetic modeling and MR-driven motion compensa-tion strategies for enhancing the theranostic value of molecular imaging particularly in cardiology, oncology and neurology. Previously, he was appointed as a research associate in the Division of Nuclear Medicine at University Hospital of Geneva, Switzerland (2014-2015) and the Division of Nuclear Medicine at Johns Hopkins University Hospital, Baltimore, MD, USA (2011-2013). Dr. Karakatsanis received his Bachelor and Masters

Dr. O'Halloran is a medical physicist working to develop and apply imaging technology to help patients with neuropsychiatric disease. Using MRI, primarily diffusion-weighted MRI, Dr. O'Halloran studies changes in the brain associated with diseases such as schizophrenia, depression, drug addiction, and epilepsy. Dr. O'Halloran is studying similar approaches to improve planning of surgical interven-tions for patients with a range of conditions including Parkinson's disease and brain tumors.

Rafael O’Halloran, PhD

Francesco Padormo, PhD

Scientific Biography: Dr Francesco Padormo obtained both his MSci (Physics, 2008) and PhD (MRI Physics, 2012) from Imperial College, London. He then became Research Associate at King’s College London, working in collaboration with the University of Oxford on Ultra-High Field MRI. In 2016 he moved to the Translational and Molecular Imaging Institute at Mount Sinai Hospital, continuing his research in the lab of Dr Priti Balchandani.

Artistic Biography: Fran Padormo attended Verulam School, UK, obtaining an end of year grade of E (Art, 2000), the lowest mark he received in his entire academic career. His lack of natural ability was much derided among family, friends, and teachers. This motivated him to abandon the arts and focus on the mathe-matical sciences. In 2015, in an attempt to broaden his horizons, he attended a course at The Art Academy, London. He was awarded an E. This is his first exhibition.

Sarayu Ramachandran, MS

Sarayu Ramachandran is best known for her work in surface and volume renderings of Magnetic Resonance (MR) and Computed Tomography (CT) images. She specializes in using the OsiriX software (Pixmeo SARL, Switzerland) to depict the human body and vascular system in spectacular color and fine detail. Sarayu completed her B. E. at the University of Mumbai and her M. S. at Columbia University, neither of which prepared her for a life in the creative arts. After graduation she worked on ultrasound imaging at the Riverside Research Institute. She joined TMII in 2009, and currently works on image analysis of cardiovascular MR images and as the data manager for clinical drug trials. Though underappreciated by her peers, she hopes that her pieces will become collectors’ items upon her untimely, and no doubt dramatic, death.

Alan, Seifert, PhD

Alan completed his Ph.D. in Bioengineering on solid-state multinuclear MRI of cortical bone at the University of Pennsylvania and joined TMII as a postdoctoral fellow in August 2015. His main research project involves technical development and translation of functional and diffusion MRI methods at 7 T for the study of pain modulation in the brainstem and spinal cord. His other research interests include radiofrequency coil engineering, high-dielectric materials for passive B1+ shimming, relaxometry, and solid-state (UTE/ZTE) imaging of myelin and calcified tissues.

biomedical engineering. He received a bachelor degree in bioengineering in 2005 and a master degree in biochemis-try/immunology in 2008, both from China. After that, he continued his study in the U.S. and received a Ph.D. degree in 2014 from Icahn School of Medicine at Mount Sinai with Drs Zahi Fayad and Willem Mulder, where he developed nanomaterial-based immunotherapies for cardiovascular diseases and cancer. Afterward, he took a postdoctoral position at Memorial Sloan Kettering Cancer Center with Dr. Thomas Reiner, where he developed cancer immuno-therapies for solid tumors and imaging probes for oncological nuclear imaging. Jun has published 24 peer-reviewed papers, given over 10 conference presentations, won 8 research awards, and filed 1 patent.

Jun Tang, PhD

Jun joined the Cancer Research Institute (CRI) in January 2017 as a senior research analyst in CRI’s Clinical Accelerator and Venture Fund, where he uses his scientific training to accelerate the clinical development of novel immuno-on-cology (IO) combination therapies. In this unique nonprofit venture fund, Jun and his colleagues identify the current IO clinical landscape, create innovative combination therapy concepts, and collaborate with leading clinical investigators to evaluate these concepts with innovative clinical trials. They also secure internal and external investment to fund the trials and feed the financial returns from successful studies back to fund the future trials. This evergreen venture model capitalizes on the unique position of CRI that connects academia, biophar-maceutical industry, philanthropists, and cancer patients.

Prior to CRI, Jun spent more than a decade on research in immunology and

Roey Tsemah

Roey Tsemah (b. 1983) is an Israeli visual artist based in Amsterdam. Fascinated by digital technologies, Roey experiments with interactivity both online and in the physical world. By creating multilayers of content, Roey invites the viewer to reexamine his perception of the here and now.

In 2015, Roey founded Whitestone - an initiative to help musicians release interactive audiovisual albums online. Whitestone works as a hub, connecting visual artists, creative developers and VR artists with musicians. It organizes hackathons, workshops and contests as well as self-initiated productions.

Bei Zhang, PhD

Bei Zhang received her PhD from the Institute of Electronics at the Chinese Academy of Science. In 2008 she came to the US and began designing and building specialized coils for MRI. In 2013 Dr. Zhang joined the Translational and Molecular Imaging Institute as an Associate Scientist to establish a coil development program.

Yiming Zhao, PhD

Yiming Zhao received his PhD in luminescent nanomaterials from Utrecht University in the Netherlands. Since 2013, he joined TMII at Icahn School of Medicine at Mount Sinai as a Postdoc Fellow and worked on nanomedi-cine and molecular imaging.

I have contacted the other author Jian Sun. However, he does not wish to show his information as he thought he was only helping with the graphic making and did not evolve in the science part. I guess it is better to only list one author then.Please find attached portrait.

Exhibition Curator

A graduate of the School of Visual Arts in New York City, Veronica Szarejko is a fine art photographer who, in 2007, was hired by the Department of Neu-roscience to manage the Digital Media Center. After receiving presentations with amazing scientific images from the various scientists at The Friedman Brain Institute, Veronica was inspired to curate an exhibition of “brain” images. Thus was born the “Art of the Brain”.

She brought this idea to fruition and now, as part of Brain Awareness Week, she curates and produces the "Art of the Brain" exhibition. This year, she was honored to be asked to curate the Translational and Molecular Imaging Institute (TMII) exhibition. The success of these exhibitions has lead to projects linking the artistic work at Mount Sinai with that of other hospitals and institutions.

Veronica still pursures her personal work. Her photo-graphs have been collected and exhibited in the United States and abroad. Her work has been displayed at the Hungarian Multicultural Center in Balatonfured, Hungry, the Society for Contemporary Photography in Kansas City, MO and The Museum of Photography in Rafaela, Argentina. Her solo credits include exhibitions at the University of Nevada in Reno, Nevada, Soho Photo Gallery in New York City and the Instituto Cultural Peruano Norteamericano in Lima, Peru, where her work is part of their permanent collection.

Veronica Szarejko