what%to%expect%before%entering% clinics…%% · ↓ pcv/ n ts (i.e., 25%/7 g/dl) ↑ pcv/n ts...
TRANSCRIPT
What%to%expect%before%entering%clinics…%%
Justine A. Lee, DVM, DACVECC, DABT CEO, VetGirl [email protected] @VetGirlOnTheRun @drjustinelee
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Introduc7on%
Jus7ne%A.%Lee,%DVM,%
DACVECC,%DABT%
CEO,%VetGirl%%
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Find us on social media
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! VetGirl%ELITE%($199)%=%free%for%veterinary%students!%
! Call%in%from%Smart%Phone!%
! Email%/%contact%with%ANY%ques7ons%
Come%prepared%
HOW$TO$GET$A$GOOD$HISTORY$
How%to%take%a%good%history%
• Introduce%yourself%then%take%control%– 18%second%rule%
• Pet%their%pet!%
• Quick,%but%thorough%– 15^20%minutes%
• EMR/UVIS%– Type%as%you%go%– Spelling!%– Professional!%
How%to%take%a%good%history %%
• Presen7ng%complaint%(PC)%
• Details%– Dates,%quan77es,%vomi7ng%vs.%regurg,%dysuria,%hematuria%(stream?),%7me%of%toxin,%7me%of%going%down%
– Start%from%the%beginning:%PMHX%– The%three%Ts:%
• Trauma%• Toxins%• Ticks%
• �Is%there%anything%else%I%can…?�%
Presen7ng%it%to%the%Doc%
• Totally%different%from%what%the%o%will%tell%us%
• Quick,%efficient,%organized%
• Start%with:%– Signalment%– PC%– Physical%exam%findings%– Problem%list%– Your%plan%
• Rule%outs%%• Diagnos7cs%
#1%Physical%examina7on%
• Efficient%• Easily%repeatable%
– Serial%exams%
• Inexpensive%• Fine^tuned%%• Focused/targeted%• Subjec7ve%
• Tips:%%– Palpate%aler%euthanasia%– Palpate%under%anesthesia%– Palpate%abnormal%
%
What%people%forget:%%Importance%of%TPR/weight%
• Always%weigh%the%pa7ent%daily%
• Don�t%use%the%carrier%(too%much%variability!)%
• Note%what%scale%you%weighed%the%pa7ent%on%(on%ICU%sheet)%
Weight%• Example:%30%kg%dog,%10%%dry%
– Dehydra7on:%30%kgs%X%0.1%X%1000%mls%=%3000%mls%replacement%
– I%L%=%1%kg%
– You%expect&this%dog%to%gain%to%33%kgs%once%hydrated!%
• Take%home%message:%weight%SID^QID!%
THE$ICU$SHEET$
ICU%sheets%
• How%to%cross%out%an%error%
• Document,%document,%document!%– Observa7ons%– To%x^ray,%AUS,%visi7ng%o%
• Every%other%line%
• Black%ball%point%pen%%%
You&touch&the&animal?&&You&write&it&down.&
• mcg%vs.%mg%vs%%μg%"%1000%mcg%to%1%mg%%
• 0.75%mls%vs%75%mls%%• Honesty,%honesty,%honesty!%
Examples%of%documenta7on%
• Catheter%placement%
• Labeling%catheters%
• Unblocking%a%cat%–%what%was%it%like?%
• Subjec7ve%–%does%the%pa7ent%look%nauseated?%
• FAST%ultrasound%exam%%
ICU%sheets%
• Save%those%lines!%%– Need%a%CBC%drawn%at%8%am?%%– Flip%+%lube%eyes%
• Assess%your%own%pa7ent%frequently%yourself!%
• Order%your%drugs%efficiently%– Cost%effec7ve%– Wasteful%– Recycle/return%ziploc%bags%to%pharmacy%
Be%efficient%
• Disconnec7ng%dog%for%AUS%–%take%it%outside%before%or%aler%(unless%they%need%a%cysto)%
• Minimizes%#%of%hep%flushes/disconnec7ng%"%errors%• Weight?%
• Save%a%walk%for%ICU%techs%if%he�s%already%out%
• Owners%=%walk%dogs%
• S7cking%dogs/mean%cats%
Don’t%get%biuen…%
FORMULAS$TO$KNOW…$
• No%longer%“shock%dose”%of%fluids%(60^90%ml/kg):%
– Instead:%1/3%of%a%shock%bolus%aliquot%(20^30%mls/kg)%
• Blood%transfusion%dose:%10^20%mls/kg%
• DPL%dose:%20%ml/kg%
%
• 3^5%days,%5^7%days,%10^14%days%
CLINICOPATHOLOGIC$TESTING$
BIG%4%vs.%CBC/CHEM/UA%
• ER%=%40%%outpa7ent%
• Would%you&spend%$300%for%blood%work%each%7me%your%dog%vomited?%
• BIG%4%+%EG8%vs.%complete%blood%work%
↓ PCV/ N TS (i.e., 25%/7 g/dL) ↑ PCV/N TS
(i.e., 65%/7 g/dL) N PCV/↓ TS (i.e., 40%/5 g/dL)
N PCV/↑ TS (i.e., 40%/9 g/dL)
↑ PCV/↑TS (i.e., 66%/8 g/dL)
↓ PCV/ ↓ TS (i.e., 25%/5 g/dL)
Hemolytic anemia Polycythemia vera Protein-losing enteropathy (PLE)
Multiple myeloma Hemocon- centration Chronic blood
loss (Melena) Aplastic anemia Hyperthyroidism Protein-losing
nephropathy (PLN)
Feline infectious peritonitis (FIP) Blood loss
(subacute)
Pure red blood cell aplasia Cushings Liver failure (lack
of production of albumin)
Chronic globulin stimulation (i.e., dental, skin disease)
Anemia of chronic disease Hemorrhagic
Gastroenteritis (HGE)
Acute blood loss (with splenic contraction)
Severe dehydration + anemia (i.e., CRF)
Is the sample hemolyzed? Icteric? # IMHA
EPO-producing tumor (renal) Third spacing Lipemic serum
BIG%4:%%Don’t%forget%that%blood%smear!%
• Checking%for%the%presence%of%WBC%
– Parvovirus%puppies%
• Checking%for%the%presence%of%platelets%– Epistaxis,%bruising%from%ITP%
– 1%plt/HPF%=%10,000%–%15,000%plt%
• Checking%for%the%presence%of%spherocytes%– DDX:%IMHA%
– Found%in%80%%of%IMHA%pa7ents%
Coag%Quickies%
• Prothrombin%(PT):%extrinsic%+%common%– Elevated%quickly%with%Vitamin%K%roden7cides%– Vitamin%K%dependent%factors:%II,%VII,%IX,%X%– Half^life%of%VII:%7%hours%
• Ac7vated%par7al%thromboplas7n%7me%(PTT):%intrinsic%+%common%
• Ac7vated%clo{ng%7me%(ACT):%intrinsic%+%common%+%platelets)
• ACT%=%PTT%
Coag%quickies:%
• PT/PTT%never&affected%by%thrombocytopenia!%
• Buccal%mucosal%bleeding%7me%(BMBT)%and%ACT%– If%thrombocytopenic%(<50,000),%don�t%bother%
• Clinical%thrombocytopenia%– <%20^30,000%platelets%%
DRUG$CALCULATIONS$
Basic%calcula7ons%
• %%=%�0�%+%mg/ml%
• Lasix%5%%=%50%mg/ml%
• 50%%Dextrose%=%500%mg/ml%
• 25%%Mannitol%=%??%
When%in%doubt…%
• If%it%doesn�t%feel%right,%it�s%not.%
• If%it’s%not%clear,%it%doesn’t%go%IV%(for%the%most%part).%– Sucralfate%IV%– AlOH%IV%– Clinicare%IV%
• Ask%
• Intern%director%screaming%at%intern%
– Digoxin%dosing%
Drug%administra7on%
• Drug%in%mgs%X%concentra7on%of%ml%=%amount%%% % % % % %mgs%
• Dog:%30%kgs,%%Dose:%Pepcid%0.5%mg/kg%SID%IV%
• 30%kgs%X%0.5%mgs/kg%=%15%mgs%
• 15%mgs%X%1%ml/10%mgs%=%15/10%=%1.5%mls%
Con7nuous%Rate%Infusions%(CRIs)%• Calculate%fluid%rate%
• Calculate%how%many%�hours�%are%in%that%whole%bag%of%fluids%
• Calculate%dose/hour%
• Mul7ple%the%#%of%hours%in%the%bag%by%the%dose/hour%
• Convert%to%mls%=%how%many%mls%to%add%into%the%total%bag%of%fluids%
CRI%of%5%mcg/kg/minute%of%Dopamine,%%30%kg%dog%
• Fluid%rate%of%5%mls/hour%
• 250%ml%bag%of%0.9%%saline/5%mls%per%hour%=%50%hours%in%the%bag%
• 5%mcg%X%30%kgs%X%60%minutes%=%9000%mcg/hour%– 9000%mcg/hour%=%9%mgs/hour%
• 50%hours%in%a%bag%X%9%mgs/hour%=%450%mgs/bag%
• 450%mgs/bag%X%1%ml/40%mgs%=%11.25%mls/bag%
Dextrose%CRIs%% % % %%%%%C1%X%V1%=%C2%X%V2%
%• Make%a%2.5%%dextrose%mix%to%IVF%%
• 50%%dextrose%=%500%mg/ml%
• (50%)(X%ml)%=%(2.5%)(1000%ml)%
• (X%ml)%=%50%ml%
• Remove%50%mls%from%a%liter%bag%of%fluids%and%replace%it%with%50%ml%of%50%%dextrose%
Seriously,%the%hardest%part%of%EG?%% % % %C1%X%V1%=%C2%X%V2%%
• Make%a%7%%ethanol%solu7on%with%Everclear%(check%proof&8&190%proof,%95%%alcohol):%%
• (95%)(X%ml)%=%(7%)(1000%ml)%
• (X%ml)%=%74%ml%
• Remove%74%mls%from%a%liter%bag%of%fluids%and%replace%it%with%74%ml%of%190%proof%vodka%
VENOUS$BLOOD$GASES…$JUST$GUESS$METABOLIC$ACIDOSIS$
KISS:%interpre7ng%blood%gas%
1. pH% % %7.35^7.45%
2. BE% % %^3%to%+3%
3. pCO2% % %30^35%mmHg%
4. HCO3 % %20^24%mmHg%
5. pO2% % %80^100%mmHg%
Tips%on%acid^base%• #1%disturbance:%metabolic%acidosis%
• pCO2%%%=%acid%
• HCO3%=%buffers%acid!%
• Venous%pCO2%vs.%arterial%pCO2%%– Difference%of%5^10%mmHg%
%
pH% % %7.35^7.45%BE% % %^3%to%+3%pCO2% %30^35%mmHg%HCO3 %20^24%mmHg%pO2%% %80^100%mmHg%
Steps%of%blood^gas%analysis%
1. pH%=%acidemic%vs.%alkalemic?%
2. BE%=%truest%component%of%metabolic%component%
3. pCO2%=%evalua7on%of%respiratory%component%
4. Hypoxic?%
5. A^a%gradient%%A:%[760%mmHg%X%FIO2]%
%%%%%%150%–%[pCO2X%1.2]%
6. Compensatory?%
pH% % %7.35^7.45%BE% % %^3%to%+3%pCO2% %30^35%mmHg%HCO3 %20^24%mmHg%pO2%% %80^100%mmHg%
Expected%magnitude%of%compensa7on%to%a%primary%event%
Primary Event
Expected compensation
Metabolic Acidosis
Each 1 mEq/L ↓ HCO3- PaCO2 ↓ by 0.7 mmHg
Expected PaCO2 = 35 – [(22-HCO3) X 0.7] mmHg
Metabolic Alkalosis
Each 1 mEq/L ↑ HCO3- PaCO2 ↑ by 0.7 mmHg
Expected PaCO2 = 35 + [(22-HCO3) X 0.7] mmHg
Expected compensation
Respiratory Acidosis Acute Chronic
Each 1 mmHg ↑ pCO2 HCO3
- ↑ by 0.15 mEq/L Expected HC03 = 22 + [(pCO2 – 35) X 0.15] Each 1 mmHg ↑ pCO2 HCO3
- ↑ by 0.35 mEq/L Expected HC03 = 22 + [(pCO2 – 35) X 0.35]
Respiratory Alkalosis Acute Chronic
Each 1 mmHg ↓ pCO2 HCO3
- ↓ by 0.25 mEq/L Expected HC03 = 22 - [(35 - pCO2) X 0.25] Each 1 mmHg ↓ pCO2 HCO3
- ↓ by 0.55 mEq/L Expected HC03 = 22 - [(35 - pCO2) X 0.55]
11%yo%FS%Dachshund%• Venous%• pH% % %6.940%
• PCO2% %26.2%mmHg%
• PO2% %52.2%mmHg%
• BE% % %^27%mmol/L%
• HCO3 %5.9%
• O2%Sat %71.6%%
• Severe%metabolic%acidosis%with%compensatory%respiratory%alkalosis%
• PaCO2:%35–%[(22^HCO3)X0.7]%
%
• Compensatory%
pH% % %7.35^7.45%BE% % %^3%to%+3%pCO2% %30^35%mmHg%HCO3 %20^24%mmHg%pO2%% %80^100%mmHg%
10%yo%FS%Bichon%• PC:%Cushings,%PTE%• Room%air%
• Arterial%• pH% % %7.334%
• PCO2% %23.7%mmHg%
• PO2% %81.3%mmHg%
• BE% % %^13.3%mmol/L%
• HCO3 %12.5%
• O2%Sat %94.8%%
pH% % %7.35^7.45%BE% % %^3%to%+3%pCO2% %30^35%mmHg%HCO3 %20^24%mmHg%pO2%% %80^100%mmHg%
10%yo%FS%Bichon%• Arterial%• pH% % %7.334%• PCO2% %23.7%mmHg%• PO2% %81.3%mmHg%• BE% % %^13.3%mmol/L%• HCO3 %12.5%• O2%Sat %94.8%%
• Mixed%acid%base:%%Metabolic%acidosis%and%respiratory%alkalosis%
• PaCO2%=%35%–%[(22^HCO3)%X%0.7]%mmHg%=%28%
• Compensa7on%for%m.%acidosis%should%be%a%pCO2%of%28.%%Dog%is%hyperven7la7ng%(not%overcompensa7ng!)%
• A^a:%%81^[150^23.7(1.2)]%=%40%
• Pulmonary%parenchymal%disease!%%
pH% % %7.35^7.45%BE% % %^3%to%+3%pCO2% %30^35%mmHg%HCO3 %20^24%mmHg%pO2%% %80^100%mmHg%
ASSESSING$FLUID$NEEDS$(HYPOVOLEMIA$VS.$DEHYRATION)$BETTER$
For%those%of%you%mathema7cally%impaired%under%cor7sol%s7mula7on…%
• Shocky%dog?%• No%calculator?%• Add%a%“0”%to%the%pound%weight%
• 77%lb%dog%presents%tachycardiac,%shocky,%pale,%poor%pulse%quality%aler%HBC%– 77%+%0%=%770%mls!%
Physical%assessment%of%dehydra7on%
% dehydration Clinical signs
<5% Not detectable
5-6% Subtle loss of skin elasticity
6-8% Definite delay in return of skin to normal position Slight prolongation of CRT Possibly dry mm
10-12% Tented skin stands in place Definite prolongation in CRT Sunken eyes Dry mm Possible signs of shock
12-15% Definite signs of shock Death imminent
Evalua7ng%hydra7on:%%10%%dry%Labrador,%30%kgs%
$PCV/TS $ $Sp$Gr. $ $Weight$%55/9 %% %1.029 %%% %30%kgs%
%40/7 % %1.024 %%% %31%kgs%
%35/5 % %1.015^1.018% %33%kgs%
Not%assessing%hydra7on%beuer!%
• Sp.%gravity%1.015^1.018%
• Urine%volume%
• Drinking%water%in%the%cage%
SQ%fluids:%%How%much%can%you%give?%
• Dose%=%�maintenance%fluids�%
• 30%kg%dog%X%50%ml/kg/day%=%1500%mls%
• 1%L%SQ%once%
BEING$SCARED$TO$PENETRATE$BODY$CAVITIES$
%[With%a%18%g%needle%and%the%good%thrust%of%the%hand,%there%is%no%body%cavity%you%can’t%penetrate…]%
– House&of&God,%Dr.%Shem%
%
Thoracocentesis%• Supplies:%
– 20%cc%syringe%– 3%way%stopcock%– 16^22%ga.%needle%or%%%%%buuerfly%catheter%
– Extension%se{ng%
– Empty%bowl%
– +/^%seda7on%• Butorphanol:%%0.2^0.8%mg/kg%IM%or%IV%
• Diazepam:%%%%%0.1^0.25%mg/kg%IV%%
Abdominocentesis%
• Shave%a%large%area%• Alcohol%spray%%
– 2%minute%contact%7me,%degreaser%
• Scrub%• Gloves?%
Loca7on%for%performing%FAST%
• Caudal%to%the%xyphoid%• Cranial%to%the%bladder%• Right%gravity^dependent%%• Lel%gravity^dependent%
Figure%courtesy%of%Boysen%SR%from%IVECCS%proceedings%2006.%
Your%job%
• Know%your%pa7ent%– Take%good%care%of%them!%– Treat%the%pa7ent%the%same%way%
you%would%if%it%was%your%pet.%
• Learn%how%to%do%�tedious�%procedures%– Keeping%pa7ents%clean%and%dry%– Doppler%– Strong%work%ethic%
• Team%work%
• Communicate%
• Read%up%at%home%– 5^minute%guide%– Not%Wikipedia%
• Stay%hydrated%
Baby%boomer%vs.%X%vs.%Y%• Strong%work%ethic%
– Put%in%your%7me%and%hours%
– Deteriora7on%in%veterinary%medicine%
• You%don�t%go%home%un7l%the%clinician%goes%home%
• Play%nicely%
• Love%up%your%technical%staff%
• Only%year%to%learn%
• You%can%do%anything%as%a%veterinarian…%
• Save%lives%and%experiment%– CSF%taps%on%cats%
• Learn%how%to%prac7ce%�street�%medicine%– Learning%from%people%you%didn�t%think%you%could%learn%from!%
• Trust%your%physical%exam%
• Learn%from%your%mistakes…%
• Complete%your%bucket%list%
%@VetGirlOnTheRun%%%VetGirlOnTheRun%%%[email protected]%%[email protected]%%%%%%%%
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