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People Are Reading Related Topics advertisement The Effects of Masturbation on Testosterone Types of Medical Steroids Facts on Anabolic Steroids Effects of Steroids on the Body The Good and Bad Effects of Steroids The Short Term Side Effects of Steroids What Are the Side Effects of Prescription Steroids? Home / Diseases & Health Conditions / Addiction & Recovery / Medical Marijuana Use / What Are the Medical Uses of Steroids? Tweet Tweet 0 0 PRINT WHAT ARE THE MEDICAL USES OF STEROIDS? Jun 11, 2010 | By Like 1 Send Dr. Shavon Jackson-Michel Photo Credit body builder image by Alex from Fotolia.com There are two classes of steroids used in medicine. Corticosteroids are drugs derived from the adrenal sourced hormones, cortisol and corticosterone. These hormones affect the immune system by suppressing inflammation. Therefore, drugs such as prednisone affect inflammation. Additionally, anabolic or androgenic steroids are those commonly associated with weight-lifting. These steroids are derived from testosterone-like hormones and cause the body to accumulate muscle mass and rebuild tissues. In medicine, anabolic steroids can be used after a serious injury, like a burn or chronic illness. REDUCE INFLAMMATION Corticosteroids are used to treat a variety of inflammatory conditions, including but not limited to, chronic asthma and osteoarthritis. The inflammation occurring in these diseases leads to tissue damage, deterioration and increased sensitivity. In the case of asthma, this sensitivity promotes the airways to become over-reactive to allergens, exercise and other stimulants. Increased activity promotes increased bronchoconstriction and asthma attacks. The inflammation of arthritis causes the lining of the joint to become further damaged and speeds the rate of wear and tear. Professor Barnes of the Imperial College of London found that chronic conditions such as asthma unwinds portions of DNA that signal inflammation. Barnes discovered that steroids work by reversing this process, putting unwound DNA back into it wound form. PAIN TREATMENTS As a result of the powerful anti-inflammatory effects of corticosteroids, they are commonly used to treat pain conditions. The four cardinal signs of inflammation are heat, redness, pain and restricted movement. Therefore, by treating inflammation decreases in pain will result. Generally, when prescribed for pain corticosteroid will be given in low doses and for short terms, as long term steroid use is associated with many side effects. Interestingly, The American Osteopathic College of Dermatology notes that one of the side effects of long term oral steroid use is osteoporosis and a condition known as avascular necrosis. Both conditions can lead to extreme joint pain and an increased risk for fractures. TREAT AUTOIMMUNE DISEASE Oral corticosteroids are also used in conditions of autoimmunity. These conditions can include inflammatory bowel diseases, scleroderma, lupus or rheumatoid arthritis. In autoimmune diseases, the white blood cells and other immune cells attack the body's own tissues. A 1999 article from the "Australian Prescriber" journal notes that steroids are usually used in high doses for a short period of time to causes a remission or reduce the progression of the disease. The steroids create a short-term reduction in white blood cell counts by either interfering in the way they are recycled or directly killing them. WEIGHT GAIN Sponsored Links You Suffer From Stress? Make Your 2013 Stress Free. Feel Calm, Feel Great. Central HK www.pangea.com.hk RELATED SEARCHES: Back Pain Medical Medical Information MD Medical Medical Physicians Symptoms Medical Search WHAT'S HOT: The Truth About Eggs LIVESTRONG Blogs Cold & Flu Center Must See Videos Sign up for our Newsletter! FOOD FITNESS HEALTH WEIGHT LOSS LIFESTYLE TRACK CALORIES COMMUNITY BLOGS Login or Register OFFICIAL PARTNER OF THE LIVESTRONG FOUNDATION CANCER SUPPORT SHOP TEAM LIVESTRONG DONATE What Are The Medical Uses Of Steroids? | LIVESTRONG.COM http://www.livestrong.com/article/146247-what-are-the-medic... 1 of 3 4/8/13 2:08 PM

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Page 1: What Are The Medical Uses Of Steroids? | LIVESTRONG · WHAT ARE THE MEDICAL USES OF STEROIDS? Jun 11, 2010 | By Dr. Shavon Jackson-Michel Like 1 Send Photo Credit body builder image

People Are Reading Related Topics

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The Effects of Masturbation onTestosterone

Types of Medical Steroids

Facts on Anabolic Steroids

Effects of Steroids on the Body

The Good and Bad Effects of Steroids

The Short Term Side Effects ofSteroids

What Are the Side Effects ofPrescription Steroids?

Home / Diseases & Health Conditions / Addiction & Recovery / Medical Marijuana Use / What Are the Medical Uses of Steroids?

TweetTweet 00PRINT

WHAT ARE THE MEDICAL USES OF STEROIDS?Jun 11, 2010 | By Like 1 SendDr. Shavon Jackson-Michel

Photo Credit body builder image by Alex from Fotolia.com

There are two classes of steroids used in medicine.Corticosteroids are drugs derived from the adrenalsourced hormones, cortisol and corticosterone. Thesehormones affect the immune system by suppressinginflammation. Therefore, drugs such as prednisoneaffect inflammation. Additionally, anabolic orandrogenic steroids are those commonly associatedwith weight-lifting. These steroids are derived fromtestosterone-like hormones and cause the body toaccumulate muscle mass and rebuild tissues. Inmedicine, anabolic steroids can be used after aserious injury, like a burn or chronic illness.

REDUCE INFLAMMATIONCorticosteroids are used to treat a variety ofinflammatory conditions, including but not limited to,chronic asthma and osteoarthritis. The inflammationoccurring in these diseases leads to tissue damage,deterioration and increased sensitivity. In the case ofasthma, this sensitivity promotes the airways tobecome over-reactive to allergens, exercise and otherstimulants. Increased activity promotes increasedbronchoconstriction and asthma attacks. Theinflammation of arthritis causes the lining of the joint to

become further damaged and speeds the rate of wear and tear. Professor Barnes of the Imperial College ofLondon found that chronic conditions such as asthma unwinds portions of DNA that signal inflammation.Barnes discovered that steroids work by reversing this process, putting unwound DNA back into it wound form.

PAIN TREATMENTSAs a result of the powerful anti-inflammatory effects of corticosteroids, they are commonly used to treat painconditions. The four cardinal signs of inflammation are heat, redness, pain and restricted movement.Therefore, by treating inflammation decreases in pain will result. Generally, when prescribed for paincorticosteroid will be given in low doses and for short terms, as long term steroid use is associated with manyside effects. Interestingly, The American Osteopathic College of Dermatology notes that one of the side effectsof long term oral steroid use is osteoporosis and a condition known as avascular necrosis. Both conditions canlead to extreme joint pain and an increased risk for fractures.

TREAT AUTOIMMUNE DISEASEOral corticosteroids are also used in conditions of autoimmunity. These conditions can include inflammatorybowel diseases, scleroderma, lupus or rheumatoid arthritis. In autoimmune diseases, the white blood cells andother immune cells attack the body's own tissues. A 1999 article from the "Australian Prescriber" journal notesthat steroids are usually used in high doses for a short period of time to causes a remission or reduce theprogression of the disease. The steroids create a short-term reduction in white blood cell counts by eitherinterfering in the way they are recycled or directly killing them.

WEIGHT GAIN

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Anabolic steroids increase protein building and skeletal muscle mass. A 2000 Annuals of Internal Medicinearticle notes that wasting syndromes identified in conditions such as HIV/AIDS and end-stage cancer aredefined by the word cachexia. Cachexia was described as being an inflammatory event that ultimately leads tomuscle breakdown, weight loss not countered by increased food consumption, fatigue, malaise, alteredconsciousness and bone marrow suppression among many other changes. These changes were described asa hypoanabolic state and the author states that anabolic steroid use may be helpful. When taken with a highprotein diet, anabolic steroids increased weight gain.

PREVENT ANEMIAAnemia results from a deficiency of or inability of red blood cells to properly bring oxygen to the tissues. Theproduction of new red blood cells occurs in the bone marrow and this process is monitored by the kidneys.The kidneys produce the hormone, erythropoietin to signal increased red blood cells production when itsenses that the oxygen level in the blood is too low. The 2000 article states that anabolic steroids have beenused when the kidneys begin to fail in chronic kidney disease to help stimulate red blood cell production andprevent anemia.

REFERENCESThe Royal Society: "How Steroids Switch Off Inflammation: Rewinding DNA"

The American Osteopathic College of Dermatology: Steroids (Oral Cortisone)

Australian Prescriber: "Corticosteroids in Autoimmunity"

American College of Physicians-American Society of Internal Medicine: "Cachexia"

Article reviewed by Jenna Marie Last updated on: Jun 11, 2010

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