INFLAMMATORY JOINT DISEASES

BY DARTI WIBISONO

22/04/2023 created by darti

created by darti

INFLAMMATORY JOINT DISEASES

OSTEOARTHRITIS

RHEUMATOID ARTHRITIS GOUT

SYNOVITIS BURSITIS

22/04/2023

Rheumatoid nodles

SYNOVITIS

created by darti

ARTHRITIS

BURSITIS

22/04/2023

created by darti

BURSITIS

22/04/2023

created by darti

Inflammation of Tendonitis/bursitis

22/04/2023

OSTEOARTHRITISDEGENERATIVE ARTHRITIS

DEGENERATIVE JOINT DISEASE

22/04/2023 created by darti

created by darti

DD

RA is a systemic disease, which means it can affect other organs in the body

GOUT is a disorder of purine metabolism.There is hyperuricemia (serum uric acid > 7 mg/dl)

22/04/2023

created by darti

OSTEOARTHRITIS

22/04/2023

created by darti

THE SUBCHONDRAL BONE REACTION IN OA

-SCLEROTIC -

OSTEOPOROTIC -CYSTIC

LESION

Pract.: -Ganglion

cysts-Bursitis

22/04/2023

created by darti

• The main target tissue is the synovial membrane of joints(synovitis/polyarthritis)

• Pathology,Early

• An active chronic inflammation of the synovial membrane.

Intermediate• Destruction of cartilage by enzymatic action and

granulation tissue spreading over the articular surface (PANNUS)

Late• Severe distorted joint

RHEUMATOID ARTHRITIS

22/04/2023

created by darti

SYNOVITIS

22/04/2023

PANNUS

It is an ingrowth of synovial material into a joint

created by darti22/04/2023

RHEUMATOID NODULE

The Histological appearance :• Central area of well

demarcated fibrinoid necrosis

• Palisade of histiocytes• Well collagenised

granulation tissue

Bamboo-spine : Bony union on the priphery of

the intervertebral

disc

created by darti22/04/2023

Giant Cell arteritis

created by darti

Temporal arteritis

An inflammatory condition affecting medium sized blood vessels that supply head,eyes

and optic nerves

Vision loss

22/04/2023

Giant Cell(Temporal)Arteri

tis A biopsy is recommended. 

The procedure is performed with local anesthesia.  This test allows doctors to definitively diagnose temporal arteritis.

created by darti22/04/2023

Giant Cell Arteritis,Temporal arteritis

Granulomatous arteritisSystemic Necrotizing

Vasculitis

Obliterated

lumen

created by darti22/04/2023

created by darti

GOUT

The arthritis of gout begins as acute inflammatory process affecting

ussually a great toe

microscopic

Urate crystsls deposited

22/04/2023

created by darti

MUSCLE/LIGAMENT ATROPHY

22/04/2023

created by darti

Atrophy of skeletal muscle.

There are two possible causes for the atrophy: 1) disuse 2) loss of nerve supply.

The presence of cross striations indicate that this is striated muscle and the peripheral location of the nuclei distinguishes it from cardiac muscle.

22/04/2023