INFLAMMATORY JOINT DISEASES
BY DARTI WIBISONO
22/04/2023 created by darti
created by darti
INFLAMMATORY JOINT DISEASES
OSTEOARTHRITIS
RHEUMATOID ARTHRITIS GOUT
SYNOVITIS BURSITIS
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Rheumatoid nodles
SYNOVITIS
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ARTHRITIS
BURSITIS
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BURSITIS
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created by darti
Inflammation of Tendonitis/bursitis
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OSTEOARTHRITISDEGENERATIVE ARTHRITIS
DEGENERATIVE JOINT DISEASE
22/04/2023 created by darti
created by darti
DD
RA is a systemic disease, which means it can affect other organs in the body
GOUT is a disorder of purine metabolism.There is hyperuricemia (serum uric acid > 7 mg/dl)
22/04/2023
created by darti
OSTEOARTHRITIS
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THE SUBCHONDRAL BONE REACTION IN OA
-SCLEROTIC -
OSTEOPOROTIC -CYSTIC
LESION
Pract.: -Ganglion
cysts-Bursitis
22/04/2023
created by darti
• The main target tissue is the synovial membrane of joints(synovitis/polyarthritis)
• Pathology,Early
• An active chronic inflammation of the synovial membrane.
Intermediate• Destruction of cartilage by enzymatic action and
granulation tissue spreading over the articular surface (PANNUS)
Late• Severe distorted joint
RHEUMATOID ARTHRITIS
22/04/2023
created by darti
SYNOVITIS
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PANNUS
It is an ingrowth of synovial material into a joint
created by darti22/04/2023
RHEUMATOID NODULE
The Histological appearance :• Central area of well
demarcated fibrinoid necrosis
• Palisade of histiocytes• Well collagenised
granulation tissue
Bamboo-spine : Bony union on the priphery of
the intervertebral
disc
created by darti22/04/2023
Giant Cell arteritis
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Temporal arteritis
An inflammatory condition affecting medium sized blood vessels that supply head,eyes
and optic nerves
Vision loss
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Giant Cell(Temporal)Arteri
tis A biopsy is recommended.
The procedure is performed with local anesthesia. This test allows doctors to definitively diagnose temporal arteritis.
created by darti22/04/2023
Giant Cell Arteritis,Temporal arteritis
Granulomatous arteritisSystemic Necrotizing
Vasculitis
Obliterated
lumen
created by darti22/04/2023
created by darti
GOUT
The arthritis of gout begins as acute inflammatory process affecting
ussually a great toe
microscopic
Urate crystsls deposited
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created by darti
MUSCLE/LIGAMENT ATROPHY
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created by darti
Atrophy of skeletal muscle.
There are two possible causes for the atrophy: 1) disuse 2) loss of nerve supply.
The presence of cross striations indicate that this is striated muscle and the peripheral location of the nuclei distinguishes it from cardiac muscle.
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