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WAYNE STATE UNIVERSITY
Professional Record
NAME: Robert Arking Date Prepared: Sept. l985
Date Revised: March 2007
Office Address: 3103 Biological Science Bldg.
Telephone No.: (3l3) 577-289l/2850
577-6891 (FAX)
email: [email protected] [email protected]
DEPARTMENT/COLLEGE: Biological Sciences/Liberal Arts
ADJUNCT APPOINTMENTS: Faculty Associate, Institute of Gerontology
PRESENT RANK & DATE OF RANK: Professor (1994)
WSU APPOINTMENT HISTORY: Year Appointed/Rank - l975, Assistant Professor
Year Awarded Tenure - l98l
Year Promoted to Associate Professor - l98l
Other WSU - Faculty Associate, Institute of Gerontology - 1984
DATE & PLACE OF BIRTH: July l, l936, Brooklyn, New York
CITIZEN OF: U.S.A.
EDUCATION: (List all degrees; institutions and locations)
High School: Atlantic City High School; Atlantic City, N.J.
Baccalaureate: Dickinson College, Carlisle, PA
Graduate: Temple University, Philadelphia, PA, Ph.D., 1967
Postgraduate: NIH Postdoctoral Fellow, University of Virginia, Charlottesville, VA, 1967-68 (in
the laboratory of Prof. Dietrich Bodenstein)
Research Associate and Research Assistant Professor, Developmental Biology
Center, University of California at Irvine, 1970-75 (in the laboratory of Prof.
Howard Schneiderman).
Participant in National Science Foundation's Summer Workshop in "Molecular
Techniques in Developmental Biology; UCSD, LaJolla, CA, July l970
FACULTY APPOINTMENTS AT OTHER INSTITUTIONS (all years):
Assistant Professor, Department of Zoology, University of Kentucky, Lexington, l968-70
Visiting Professor: Division of Biology, University of Michigan, Ann Arbor. Fall l982.
I learned cDNA cloning techniques in the lab of Dr. Robert Helling.
Visiting Professor, Dept. of Biological Sciences, Pusan National University, Korea,
Winter 2001. I was invited to accept a Korean Government “Expert Brain Pool”
Visiting Professorship so as to teach my course in the Biology of Aging to their
graduate students, do research in this area and mentor their faculty in the
intricacies of aging research
Fulbright-University of Salzburg Distinguished Chair in Natural Science, Winter, 2006
PROFESSIONAL SOCIETY MEMBERSHIP(S) (with dates):
Genetics Society of America (l963-2007)
Society for Developmental Biology (l979-1990)
American Society of Zoologists (l975-1990)
American Association for the Advancement of Science (l963-)
Sigma Xi (l968-)
New York Academy of Science (l970-78)
Gerontology Society of America (l985-)
American Aging Association (1999-)
British Society for Research on Ageing (2005-)
HONORS/AWARDS:
1964-66. NSF Predoctoral Cooperative Fellow, Temple Univ. (in the laboratory of Prof. Ralph
Hillman)
1967-68. NIH Postdoctoral Fellow, Univ. of Virginia (in the laboratory of Prof. Dietrich
Bodenstein).
1987-88 Summer Scholar, WSU Institute of Gerontology
1990ff Chair, Biological Sciences Section and Vice-President, Gerontology Society of America
1999; GSA Council 1998-2000; GSA Executive Committee 1999-2000; GSA
Membership Committee 2000-2004; Biological Sciences Executive Committee
1998-2004; BS Membership Committee 1990-1991; Mentor to Student Section,
Gerontology Society of America 1990-91; BS Fellowship Committee 1991-1998,
2005-2008; Public Policy Committee 2007-2010;
1998ff Editorial Board, Rejuvenation Research (formerly Journal of Anti-Aging Medicine)
2000 Faculty Recognition Award, Wayne State University (for outstanding scholarship)
2001ff Undergraduate Officer & Chair of Undergraduate Committee; responsible for
developing, implementing, and guiding the Dept’s B.S. and B.A. programs
(enrollment =~800 students).
2001 Visiting Professor, Dept. of Biological Sciences, Pusan National University, Korea,
Winter 2001. I was invited to accept a Korean Government “Expert Brain Pool”
Visiting Professorship so as to teach my course in the Biology of Aging to their
graduate students, do research in this area and mentor their faculty in the
intricacies of aging research
2002 Nominated by GSA Nominating Committee as one of two candidates for President-
elect, Gerontology Society of America. (I lost)
2002 Faculty Teaching Award, CLAS, Wayne State University
2002 Guest Editor, Journal of the American Aging Association (AGE), for Fall 2002 issue
dealing with "Genetics of Aging"
2004ff Treasurer & Exec. Board member, WSU AAUP/AFT chapter; Negotiating team member,
2002.
2005ff National Scientific Review Panel, American Federation for Aging Research (serves as
the review panel for most foundation (non-NIH) funded aging research
2006 Fulbright-University of Salzburg Distinguished Chair in Natural Sciences, Winter term
2006ff Member, Leadership Planning Committee for the Dean, College of Science and
Technology, Temple University, Phila. PA. (select committee; nominated without
my knowledge on basis of scholarship)
2007ff Member, WSU Retention Committee (select committee in the Provost’s Office to
address problems & solutions regarding undergraduate recruitment, retention,
and success)
BIOGRAPHICAL CITATIONS: American Men & Women of Science
Who’s Who in America
Who's Who in Technology Today
Who’s Who in Science and Engineering
Who’s Who Among America’s Teachers
Who's Who in the Midwest
TEACHING
A. Years at Wayne State: 32
B. Years at Other Colleges/Universities: 2 - University of Kentucky, l968-l970
C. Courses Taught at Wayne State University in Last Five Years
1. Level * Course Times Taught in Past 5 Years
Bio 390/590 Undergraduate Biology Research 10
Bio 6994* Technical Communication in Molecular Biotechnology 2
Bio 5610 Vertebrate Embryology 4
Bio 5620 Developmental Biology 4
Bio 5750/7750 Biology of Aging 6
Bio 1030 Biology for Non-majors 1
*The indicated courses were taught as voluntary overloads
2. Graduate Professional School
Lecturer, First Annual WSU/IOG Summer Institute on Issues in Aging, July 1988.
Topic entitled "Modifying the Aging Process".
Lecturer, WSU Institute of Gerontology Faculty Development Program in Gerontology, 1990.
A federally funded program to teach faculty from area colleges the fundamentals of gerontology so
that they might teach a general course in gerontology on their home campus. Responsible
for instructing these faculty in the biological aspects of aging.
Lecturer, Intensive Review of "Geriatric Medicine Program, Beaumont Hospital, 1990; 1994, 1998,
2002, 2005.
This program was designed to prepare clinically oriented physicians for their Geriatrics Board
Examinations. Responsible for lecturing on the Concepts and Theories of Biogerontology
(1990), and Biology of Aging, Themes and Concepts, (1994 ff). The program director is
Michael Madden, M.D.
Lecuturer, Intensive Review of Geriatric Medicine. Botsford Hospital Sept. 1998.
The title of my talk was "Biology of Aging: Why? How? When?
Lecturer, Molecular Toxicology 761. I have given a lecture on Toxicology and Aging for the past
fifteen years
Lecturer, WSU Institute of Gerontology “Research in the Biology of Aging”, for their Introductory
Course and Capstone Course. 1999, 2000.
Lecturer, Dept of Geriatrics, Beaumont Hospital, 2001, 2003, 2005. Research And Knowledge in
the Biology of Aging.
D. Graduate Committees Served On: (as Director) Ph.D. Dissertations Directions
Steven P. Dudas (1993)
M.S. Thesis Directed
Anthony Parente (1980), Joseph Pedelty (1983), Sandra Bergh (1984), Robert Pretzlaff
(1898), Christine Neslund (1992), Allen G. Force (1993), Dae-Sung Hwangbo (2001);
James Nelson (2003).
M.S. In Molecular Biotechnology: Program Director-Advisor
1993: Tania Hilmer, Susan M. Wykes, Robert Topping
1994: Kirit Pindolia, Thomas R. McKeon, Siqin Luo, Steven Buck
1995: Heather Leone, Dominique Wilson, Mark Bowers, David Gervasi, Kevin Ward,
Priya Menon, Scott Myrand, Hans Johnson, Russell Clift
1996: Yao Lin, Guo Lin, Irfan Lodhi, Kang Song
1997: Anita Murthy, Leslie Nixon, Kalpana Sathrasala, Chitra Sridar, Purnima Kurnool
1998: Aviva Levine, Bryan Prince, John Vettraino, Meng lim, Ibrahim Kadura, Arundhati
Majumder, Rana Sharara, Hakim Shahid, Deepa Biloikar, Amale Bonfeliga, Deepa
Biloikar. Emily Eugester, Brian Fayz, Samer Muala, Neil Cheddie, Jay Koepke.
1999: Brian Peterson, Sharmilli Moturi.
B.S. Essays Directed
(Research/Honors students who published paper in a referred journal: 1975-present)
Aaron Zveei, Elliot Feldman, Ashesh Saraiya, Karen Kalata, Steven Buck, Robert
Wells, Angela Berrios, Richard Putnam, Bernard Vlach, Richard Smith, Susan
Dwyer, Susan LaGrou, Allen Force, Sherif Soliman, John Vettraino. Jung Won Soh
E. Courses or Curriculum Development Coordinator, Molecular Biotechnology Program, 1990-2000. I was the initiator, architect and
chairman of the ad hoc committee which designed the Department's proposed M.S. Curriculum in
Molecular Biotechnology. This program is a career oriented, laboratory based graduate program
designed to teach students the knowledge and techniques associated with genetic engineering. It is
a campus wide program incorporating the knowledge and technical skills of faculty from a number
of departments throughout the University. The successful graduate from this program will have an
excellent working knowledge of recombinant DNA technologies and the terms on which they are
based. The need to present both theory and practice is reflected on the structured sequence of the
curriculum. It has proven to be both successful (in terms of student applications). The program has
attrracted to Wayne well-qualified graduates of good schools. The future of the Program is assured
now that it has attracted funding from upper administration and will become an interdisciplinary
program.
During my time at Wayne, I have developed eight new courses in order to meet the changing
needs of our students. Biology 5620 (Developmental Biology) was inaugurated in Winter l976
and has been offered every year since then. I “gave it away” this year to a new faculty person.
Biology 709 (Developmental Genetics) was first offered in Winter l979. I taught it for ca. 15
years and then „gave‟ it to other faculty with active research programs in that field. Biology 181
(Evolution for Non-majors) was developed in collaboration with Professors Levine and Cosgriff
and was offered in Spring l983& 1984. Biology 5750/7750 (Biology of Aging) was first offered
in Fall l985. This course has been adopted by the WSU Institute of Gerontology as a required
core course in their Master's and certificate programs. The lecutres in this course served as the
genesis for my book on this topic. The student response, as judged by SET scores, has been most
gratifying. BIO 7510 (Eucaryotic Gene Structure and Function) was developed as the second
semester of the department‟s two semester advanced genetic sequence. It is an intensive text and
literature-based review and analysis of modern genetics. It was first offered in Winter 1992. I
"gave away" this course to a molecular geneticist who joined the faculty in 1995. BIO 506
(Seminar in Molecuar Biotechnology), Bio 701 (Introduction to Molecular Biotechnology) and
Bio 800 (Seminar on Biotechnology were developed in connection with the Molecular
Biotechnology Program and were first offered in Fall 1991. They have evolved into Biology
6994 (Communication in Molecular Biotechnology) which emphasizes effective communication
of research results.
II. RESEARCH
A. Research Grants in Progress, Funded None.
B. Research Grants, Pending None
C. Research in Progress, Not Funded 1. Analysis of the Constituitive Dietary Restriction Mechanisms Operative in the Long
lived La Strain of Drosophila.
2. The Role of Mitochondria in the Extended Longevity Phenotype of Drosophila
D. Past Funded Research Mutational Analysis of Longevity Assurance Genes. NIA-NIH. 1 May 1994-30 April
1998. $399,020 total direct costs.
Pan-gene Blot Analysis of Longevity Assurance Gene kExpression in a Genetically
Selected Long Lived Strain of Drosophila. (With Dr. M.S.H. Ko of the WSU Center for
Molecular Biology). 1 March 1994-28 February 1995. $10,000 direct costs.
Shock Aging Research Foundation, "Molecular Genetic Analysis of Extended Longevity
in Drosophila". January 1993-December 1993. $10,000 direct costs.
WSU Research Stimulation Fund, "Molecular Genetic Analysis of Aging in Drosophila".
January 1993-December 1993. $2,000.
Glenn Foundation ofr Medical Research. "Genetic and Molecular Analysis of Aging in
Drosophia". April 1991-March 1992. $2,000 direct cost.
WSU Bioedical Research Support Program. "Antioxidant Regulation of Longevity in
Drosophila. July 1989-June 1990. $4,500.
WSU Center for Molecular Biology. "Isolation of the Imaginal Disc Specific Genes of
Drosophila. August 1988-July 1990. $6,500.
WSU Presidential Excellence Award. "A Continuing Molecular and Genetic Analysis of
Aging in Drosophila". April 1987-March 1988. $5,000.
WSU Institute of Gerontology. A Genetic and Molecular Analysis of Aging in
Drosophila". September 1986-August 1988. $32,000.
Selection of Long-lived Drosophila. NIA-NIH. December 1979 - January 1985. ca.
$300,000 total direct costs
Pattern Formation in Drosophila. NSF. 1976-1984. Average of ca. $70,000/year total
direct costs, for total sum of ~$560,000.
D. Past Fellowships, Grants and Special Awards Arking, R. "A Continuing Genetic and Molecular Analysis of Aging in Drosophila".
Summer Scholar Award, 1988, from WSU Institute of Gerontology.
Arking, R. "Molecular Biotechnology Laboratory Development", Graduate Assistant
Stipend for Curriculum Development. ORSP Educational Development Program,
Summer 1991.
Sabbatical Leave Award, Winter 1989, 1996, 2002, 2005
1989, Used this period of time to finish writing the 1st edition of my book
1996, Used this period of time to revise and write the 2nd edition of my book.
2002. Used this period of time to revise and write the 3rd edition of my book.
2006. Named as Fulbright Distinguished Chair of Natural Sciences at the University of
Salzburg; used this time to write the Ellison Medical Foundation proposal, to write a
paper for publication, and to develop the basis for a subsequent book.
U.S. CRDF funded proposal to host a workshop on "Biology of Longevity in Humans
and "Non-Humans" in Dec. 1996. Total Award=$8,000.
Korean Government “Expert Brain Pool Visiting Professorship”, Winter 2001
Guest Editor, AGE (J. American Aging Association) for Winter 2001 issue dealing with
"Genetics of Aging"
III. PUBLICATIONS
A. Scholarly Books Published/Edited (all years)
Arking, R. (1991). "Biology of Aging: Observations and Principles". xii plus 420 pp.
Prentice-Hall, Englewood Cliffs, NJ. (This is a 13 chapter, 125,000 word text presenting
the facts and theories regarding biological aging processes as seen in a wide variety of
organisms and at a variety of different organizational levels). The book is considered by
reviewers to be"....the best book in the field".)
Arking, R. (1998). "Biology of Aging: Observations nad Principles". 2nd edition
(considered by a reviewer at the time to be".....still the best book available in the field.”)
Arking, R. 2006. “Biology of Aging: Observations and Principles”, 3rd
edition. Oxford
University Press, New York. (xii plus 604 pp, 189 figures, 99 tables)
B. Chapters Published (all years) (N=20)
Arking, R. and M. Clare. (1986). Genetics of Aging: Effective selection for increased
longevity in Drosophila. In: K. Collatz and R. Sohal, eds. Insect Aging: Strategies and
Mechanisms. Springer-Verlag, Berlin. Pages 2l7-236.
Arking, R. (l987). Genetic and environmental determinants of longevity in Drosophila.
In: "Evolution of longevity in Animals: A Comparative Approach", (A.D. Woodhead
and K.H. Thompson, eds). Brookhaven Symposia in Biology, No. 34. Plenum Press,
New York. Pages 1-22.
Arking, R. (1991). Modifying the Aging Process: Chapter 1 in "Health, Illness, and
Disability in Later Life" (R. Young and E. Olson, Eds). Sage Press, Newbury Park, CA.
Arking R. (1995). "Antioxidant Genes and (Other Mechanisms Involved in the Extended
Longevity of Drosphila". In: Antoioxidants and Aging (R. Cutler, editors):pp 123-139,
Birkhauser, Basel.
Arking, R. (1995). Flies. Pp. 374-376 in : Encyclopedia of Aging, 2nd
ed. (G.L. Maddox
et al., eds). Springer Publishing Co., New York.
Johnson, T., Arking, R., Bertrand, H., Driscoll, M., Esser, K., Griffiths, A., Harley, C.,
Jazwinski, S.M., Kirkwood, T. And Osiewacz, H. ( (1995). Research on Diverse Model
systems and The Genetic Basis of Aging and longevity. In: Molecular Aspects of Aging:
A Dahlem Workshop (K. Esser and G. Martin, eds.) Pp. 61-76, John Wiley, Chichester.
Arking, R. And Woodruff, R.W. (1999). Using Drosophila in Experimental Aging
Research. In: Methods in Aging Research (B.P.Yu, ed). Pp 145-165, CRC Press, Boca
Raton.
Arking, R. (2001). Models for the study of aging: Flies. Encyclopedia of Aging, 3rd
ed.
(Gl.L. Maddox et al., eds). Springer Publishing Co., New York.
Arking, R. (2002). Oxidative Stress and Longevity Determinant Genes of Drosophila.
Chap 66 (pp. 1231-1245) in: Oxidative Stress and Aging: Advances in Basic Science (R.
G. Cutler and H. Rodriguez, eds.). World Scientific Publ. Co., Singapore.
Arking, R. (2001). The Biology of Aging: What Is It and When Will It Become Useful?.
In: International Review of Geriatric Endocrinology vol. 12: 469-487 W.B. Saunders,
Philadelphia.
Arking, R. (2003). Extending Human Longevity: A Biological Probability. In: So You
Want To Live Forever: Biological, Ethical and Social Implications (S. Post and M.
Fossell, eds.). Templeton Foundation.Oxford Press. In press
Arking, R. (2003). Theories of Biological Aging. In: Encyclopedia of Bioethics, 3rd
ed.,
(S. Post, ed.). Macmillian Publishing Co., In press.
Arking, R. 2003. Aging: A Biological Perspective. American Scientist 91(6):508-515.
Arking, R. (2004). Biological Theories of Aging. In: Encyclopedia of Bioethics, 3rd
ed.
(S. Post, ed.). Macmillan.
Arking, R. 2004. A New Age for Aging? Ethical and Scientific Questions (Meeting
Review). Rejuvenation Research, 7 (1): 53-60.
Arking, R. (2005). Models for the study of aging: Flies. Encyclopedia of Aging, 4th
ed..
(R. Sprott et al., editors). Springer Publishing Co. New York.
Arking, .R 2004. Extending human longevity: A biological probability. Chapter 8 in “The
Fountain of Youth: Cultural, Scientific, and Ethical Perspectives on a Biomedical Goal”,
SG Post and RH Binstock, eds. Oxford University Press, New York
Arking, R., V. Novoseltsev and J. Novoseltseva.. 2004. The human life span is not that
limited: Effects of multiple longevity phenotypes. In Anti-Aging Medicine: The Hype and
the Reality (S. J. Olshansky, ed.). Gerontology Soc. America, 2005. (reprint of research
paper 46)
Arking, R. 2005. Biology, Fruit Flies, and Humans: Can Extended Longevity Stretch from
One to the Other? The Gerontologist 45:418-425. (Review Essay)
Arking, R. (2006). Gene Expression and the Extended Longevity Phenotypes of
Drosophila. Chap. 21 in “Handbook of Models for Human Aging” (M. Conn, ed),
Elsevier.
C. Journal Articles Published (all years)
1.Published in Referred Journals (N=51)
Arking R. and Shaaya, E. (l969). Effect of ecdysone on protein synthesis in the larval fat
body of Calliphora. J. Insect Physiol. l5, 287-296.
Arking R. (l970). Phenogenetics of the eyeless-Dominant mutant of Drosophila
melanogaster. I. Development of the lethal larvae. J. Exp. Zool. l7l, 285-296.
Arking, R. (l975). Temperature-sensitive cell lethal mutants of Drosophila: Isolation and
characterization. Genetics 80, 5l9-537.
Arking, R., Putnam, R., and Schubiger, M. (l975). Phenogenetics of the eyeless-
Dominant mutant of Drosophila. II. The involvement of the nervous system, J. Exp.
Zool. l93, 30l-3l2.
Smith, R., and Arking R. (l975). The effects of juvenile hormone analogues on the
embryogenesis of Drosophila. J. Insect Physiol. 2l, 723-732.
Arking R. (l975). Mapping a gradient in the Drosophila leg disc by means of "genetic
surgery." In: Developmental Biology (D. McMahan, ed.). W.A. Benjamin. pp. 290-295.
Arking, R. and Vlach, R. (l976). The direct selection of mutants of Drosophila resistant
to juvenile hormone analogues. J. Insect Physiol. 22, ll43-ll5l.
Arking, R. (l978). Tissue, age and stage specific patterns of protein synthesis during the
development of Drosophila melanogaster. Develop. Biol. 63, ll8-l27.
Arking, R. and Parente, A. (l980). Effects of RNA inhibitors on the development of
Drosophila embryos permeabilized with a new technique. J. Exp. Zool. 2l2, l83-l98.
Parente, A. and Arking, R. (l980). Effect of DNA inhibitors upon DNA synthesis and
development of Drosophila embryos. J. Exp. Zool. 2l2, l95-204.
Pedelty, J. and Arking, R. (l98l). Metamorphosis of the humeral disc of Drosophila. J.
Exp. Zool. 2l6, l4l-l48.
Sodja, A., Arking, R. and Zafar, R. (l982). Actin gene expression during embryogenesis
of Drosophila melanogaster. Develop. Biol. 90: 363-368.
Bergh, S. and Arking, R. (l984). Developmental profile of the heat shock response in
early embryos of Drosophila. J. Exp. Zool. 23l: 379-39l.
Luckinbill, L.A., Arking, R., Clare, M., Cirocco, W. and Buck, S. (l984). Selection for
delayed senescence in Drosophila melanogaster. Evolution 38: 996-l003. Note: this
paper has been selected for on-line re-publication in “Classic Papers in Aging (D. M.
Waller, ed.) at http://sageke.sciencemag.org/cgi/content/abstract/sageke;2001/1/cp7
Arking, R. (l987). Successful selection for increased longevity in Drosophila: Analysis
of the survival data and presentation of a hypothesis on the genetic regulation of longevity.
Experimental Gerontology 22:l99-220.
Arking, R., Buck, S., Wells, Robert, A., and Robert Pretzlaff. (l988). Metabolic rates in
genetically based long-lived strains of Drosophila. Experimental Gerontology, 23:59-76.
Arking, R. (1988). Genetic Analysis of Aging Processes in Drosophila. Experimental
Aging Research 14(3):125-135.
Pretzlaff, R. and Arking, R. (1989). Patterns of amino acid incorporation in long lived
genetic strains of Drosophila. Experimental Gerontology. 24(1):67-81.
Arking, R. and Dudas, S.P. (1989). A Review of Genetic Investigations into Aging
Processes of Drosophila. J. American Geriatrics Society. 37:757-773.
Arking, R., and Wells, R.A. (1990). Genetic alteration of normal aging processes is
responsible for extended longevity in Drosophila. Developmental Genetics. 11:141-148.
Arking R., Buck, S., Berrios, A., Dwyer, S. And Baker, G.T. (1991). Elevated paraquat
resistance can be used as a bioassay for longevity in a genetically based long-lived strain of
Drosophila. Developmental Genetics. 12:362-370.
Buck, S., Dudas, S., Wells, r.A., Baker, G.T. And Arking, R. (1993). Chromosomal
localization and regulation of the longevity determinant genes in a selected strain of
Drosophila melanogaster. Heredity: 71:11-22.
Buck, S., Nicholson, M., Dudas, S., Wells, R., Force, a., Baker, G.T. And Arking R. (1993).
Larval regulation of adult longevity in a genetically selected long lived strain of Drosophila.
Heredity: 71:23-32.
Arking, R., Dudas, S.P. And Baker, G.T. (1993). Genetic and environmental factors
regulating the expression of an extended longevity phenotype in a long lived strain of
Drosophila. Genetica: 91:127-142.
Dudas, S.P. And Arking R. (1995). A coordinate up-regulation of antioxidant gene activities
is associated with the delayed onset of senescence in a long-lived strain of Drosophila.
Journal of Gerontology: Biological Sciences: 50A: B117-B127.
Arking, R. And Buck S. (1995). Selection for increased longevity in Drosophila
melanogaster: A reply to Lints. Gerontology: 41: 69-75.
Force, A.G., Staples, T., Soliman, S. and Arking, R. (1995). Comparative biochemical and
stress analysis of genetically selected Drosophila strains with different longevities
Developmental Genetics 17:340-351.
Arking, R., Force, A.G., Dudas, S.P., Buck, S. and Baker, G.T. (1997). Factors contributing
to the plasticiy of the extended longevity phenotypes of Drophilla. Exp. Gerontol. 31:623-
643.
Hari, R., Burde, V. And Arking R. (1998). Immunological confirmation of elevated levels of
CuZn Superoxide Dismutase protein in an artificially selected long-lived strain of Drosophila
melanogaster. Exp. Gerontol. 33:227-237.
Kuether, K. and R. Arking, 1999. Drosophila Selected for Extended Longevity Are More
Sensitive to Heat Shock. AGE 22:175-180.
R. Arking, V. Burde, K. Graves, R. Hari, S. Soliman, A. Saraiya, K. Sathrasala, S. Buck, N.
Wehr, and R. Levine. 2000. Selection for longevity specifically alters antioxidant gene
expression and oxidative damage patterns in Drosophila. Exp. Gerontol. 35(2): 167-185
R. Arking, V. Burde, K. Graves, R. Hari, S. Soliman, A. Saraiya, K. Sathrasala, and S. Buck.
2000. Identical longevity phenotypes are characterized by different patterns of gene
expression and oxidative damage. Exp. Gerontol. 35(3): 353-373.
Buck, S., J. Vettraino and R. Arking. 2000. Extended longevity of adult Drosophila is
associated with significant developmental lethality. J. Gerontology: Biol. Sci. 55A:B292-
B301.
Arking, R. 2001. Gene expression and regulation in the extended longevity phenotypes of
Drosophila. N.Y. Acad. Sci. Annals 928: 157-167.s.
Vettraino, J., S. Buck and R. Arking. 2001. Direct selection for paraquat resistance in
Drosophila involves reciprocal effects on the P450 system and the antioxidant defense
system but does not extend longevity. J. Gerontol.: Biol.Sci.: 56A: B415-B425.
Arking, R. and C. Giroux. 2001. Antioxidant genes, hormesis, and demographic longevity. J.
Anti-Aging Medicine:4: 125-136.
Arking, R. S. Buck, D.S. Hwangbo and M. Lane. 2002. Metabolic alterations and shifts in
energy allocations are corequisites for the expression of extended longevity genes in
Drosophila. NY Acad Annals: 959: 251-262 (online www.annalsnyas.org).
Novoseltsev, V.N., R. Arking, J.A. Novoseltseva and A.I. Yashin. 2002. Evolutionary
optimality applied to Drosophila experiments: hypothesis of constrained reproductive
efficiency. Evolution: 56(6): 1136-1149.
Buck, S.A. and R. Arking. 2002. Metabolic alterations in genetically selected Drosophila
strains with different longevities. J. American Aging Assoc.: 24:151-162..
Arking, R. S. Buck, D.S. Hwangbo and M. Lane. 2002. Genomic plasticity, energy
allocations, and the extended longevity phenotypes of Drosophila. Ageing Research
Reviews: 1:209-228.
Arking, R., J. Novoseltsev, D-S. Hwangbo, V. Novoseltsev and M. Lane. 2002. Different
age-specific demographic profiles are generated in the same normal-lived Drosophila strain
by different longevity stimuli. J Gerontol A Biol Sci Med Sci 2002 57: B390-398.
Kim, Y.S., H.j. Nam, N.D. Kim, H.Y. Chung, R. Arking and M.A. Yoo. 2002. The role of
xanthine dehydrogenase and aging on the innate immune response of Drosophila. J.
American Aging Assoc.24:187-194.
Novoseltsev, V.N., R. Arking, A.I. Yashin and J.A. Novoseltseva. 2002. Mathematical
modeling of life history in humans and animals (In Russian). Proc. Inst. XV, pp129-152.
Arking, R., V. Novoseltsev and J. Novoseltseva.. 2003. The human life span is not that
limited. J. Gerontology: Biol. Sci. In press.
Novoseltsev, V.N., R. Arking, J.R. Careey, J.A. Novoseltseva and A.I.Yashin. 2004. Hidden
trade-offs and individual fecundity in Drosophila and medflies. Submitted.
Novoseltsev, V.N., R. Arking, A.I. Yashin and J.A. Novoseltseva. 2002. Mathematical
modeling of life history in humans and animals (In Russian; abstract in English). Proc. Inst.
Control Sciences: Section “Control in Organizational and Medico-Biological Systems”: vol.
XV, pp129-152.
Arking, R., V. Novoseltsev and J. Novoseltseva.. 2004. The human life span is not that
limited: Effects of multiple longevity phenotypes. J. Gerontology: Biol. Sci. 59A:697-704.
(Reprinted as Review Paper 15)
Novoseltsev, VN, R. Arking, JR Carey, JA Novoseltseva and AI Yashin. Individual
fecundity in Drosophila and Medflies. Pp. 206-216 in Longevity, Aging and Degradation
Models, vol. 1 (V. Antonov, C. Huber, M Nikulin and V. Polischook, eds.). St. Petersburg
2004.
Novoseltsev VN, Arking R, Carey JR, Novoseltseva JA, Yashin AI. 2004. How an
individual fecundity pattern looks in Drosophila and medflies. Ann N Y Acad Sci. 1019:577-
580.
Noveseltsev, VN, R. Arking, JR Carey, JA Novoseltseva and AI Yashin. 2005. Individual
fecundity and senescence in Drosophila and medfly. J Gerontol A Biol Sci Med Sci. 60:953-
962.
Arking, R (2005). Multiple Longevity Phenotypes and the Transition from Health to
Senescence. Ann. N.Y. Acad. Sci. 1057:1-12.
Arking, R. 2007. Human reproductive costs and the predicted response to dietary restriction.
Rejuvenation Research: In press.
Invited Review Articles (N=19)(some duplicate listings with review article listing above)
Arking, R. and M. Clare. (1986). Genetics of Aging: Effective selection for increased
longevity in Drosophila. In: K. Collatz and R. Sohal, eds. Insect Aging: Strategies and
Mechanisms. Springer-Verlag, Berlin. Pages 2l7-236.
Arking, R. (1987). Genetic and environmental determinants of longevity in Drosophila. In:
Evolution of Longevity in Animals: A Comparative Approach (A.D. Woodhead and
K.H.Thompson, eds), pp 1-22. Brookhaven Symposia in Biology No. 34. Plenum Press,
New York.
Arking, R. (1988). Genetic Analysis of Aging Process in Drosophila. Experimental Aging
Research 14 (3):125-135.
Arking, R. (1989). Variations in the evolutionary rates shown by DNA molecular clocks.
McGraw Hill 1989 Yearbook of Science and Technology (Robert Arking, consulting
editor). Pp. 255-257.
Arking, R. And Dudas, S.P. (1989). A Review of Genetic Investigations into Aging
Processes of Drosophila. J. American Geriatrics Society. 37:757-773.
Arking, R. (1991). Modifying the Aging Process: Chapter 1 in "Health, Illness, and
Disability in Later Life" (R. Young and E. Olson, Eds). Sage Press, Newbury Park, CA.
Arking, R. (1995). Antioxidant Genes and Other Mechanisms Involved in the Extended
Longevity of Drosophila. Pp. 123-139 in: Antioxidants and Aging (R. Cutler et al., eds).
Bitkhauser-Verlag, Basel.
Arking, R. (1995). Flies. Pp. 374-376 in: Encyclopedia of Aging, 2nd ed. (G.L. Maddox et
al., eds). Springer Publishing Co., New York.
Johnson, T., Arking, R. and eight others (1995). Research on Diverse Model Systems and
the Genetic Basis of Aging and Longevity. In: Molecular Aspects of Aging: A Dahlem
Workshop Report. (K. Esser and G. Martin, eds.). John Wiley, Chichester.
Arking, R. and R.Woodruff (1999). Using Drosophila in Experimental Aging Research. Pp
145-165 In: Methods in Aging Research (B.P.Yu, ed.). CRC Press, Boca Raton, FL
Arking, R. (1999), "Drosophila As a Model System. In "The Encyclopedia of Aging," 3rd
edition (George Maddox, chief Editor). Springer Publishing Co. New York.
Arking, R. (2001). Models for the study of aging: Flies. Encylopedia of Aging, 3rd
ed..
Arking, R. (2001). Oxidative Stress and Longevity Determinant Genes of Drosophila. In:
Oxidative Stress and Aging: Advances in Basic Science (R. G. Cutler and H. Rodriguez, eds.).
World Scientific Publ. Co. In press.
Arking, R. (2001). The Biology of Aging: What Is It and When Will It Become Useful?. In:
International Review of Geriatric Endocrinology vol. 12: 469-487 W.B. Saunders,
Philadelphia.
Arking, R. (2003). Extending Human Longevity: A Biological Probability. In: So You Want
To Live Forever: Biological, Ethical and Social Implications (S. Post and M. Fossell, eds.).
In Press.
Arking, R. (2003). Theories of Biological Aging. In: Encyclopedia of Bioethics, 3rd
ed., (S.
Post, ed.). In press.
Arking, R. (2004). Biological Theories of Aging. In: Encyclopedia of Bioethics, 3rd
ed. (S.
Post, ed.). Macmillan.
Arking, R. (2005). Models for the study of aging: Flies. Encyclopedia of Aging, 4th
ed.. (R.
Sprott et al., editors). Springer Publishing Co. New York.
Arking, .R 2004. Extending human longevity: A biological probability. Chapter 8 in “The
Fountain of Youth: Cultural, Scientific, and Ethical Perspectives on a Biomedical Goal”, SG
Post and RH Binstock, eds. Oxford University Press, New York
Arking, R. (2006). Gene Expression and the Extended Longevity Phenotypes of Drosophila.
Chap. 21 in “Handbook of Models for Human Aging” (M. Conn, ed), Elsevier.
3. In Preparation (N=2)
Jung, WS, S. Hojic, and R. Arking. Dietary restriction in Drosophila depends on
mitochondrial type and is constrained by extended longevity.
Balan, V., G. Miller, K Balan, ZZ Chong, F Li, M VanBerkum, R. Arking, K Maiese and G.
Tzivion. Lifespan extension and neuronal cell protection by the Drosophila
nicotinamidase D-NAAM.
G. Astracts Published (all years) (N=34 plus)
Arking, R. And Hillman, R. (1966). The developmental genetics of the eyeless-Dominant
locus in Drosophila melanogaster. Amer.Zool. 6:512.
Arking, R. And Hillman, R. (1967). Analysis of the mode of action of the eyeless-dominant
allele. Drosoph. Inform. Serv. 42:69-70.
Arking, R. (1973). Developmental effects of a temperature-sensitive cell lethal. Genetics ,
74:59.
Arking, R. And Timberlake, W.E. (1977). Tissued specific protein patterns of Drosophila as
an indication of differential gene activity. J. Supramolecular Structure: Suppl. 1:84.
Quill, T.F. And Arking, R. (1977). Description of a new sex linked homeotic utant and an
analysis of the role of cell death in this mutant. Proc. Midwest. Regional Develop. Bil.
Conf. p. 54.
Arking, R. (1978). A new sex linked temperature sensitive mutant of Drosophila which
causes a dorsal-ventral transformation as a result of cell death. Genetics 88:s4.
Parente, A. And Arking, R. (1980). A convenient method of collecting moderately large
numbers of eggs from D. Melanogaster. Dros. Inform. Serv. 55:164-165 (Note).
Sodja, A., Zafar, R. And Arking, R. (1981). Differential actin gene expression in Drosophila
melanogaster. Proceedings of the Cleveland Symposium on Macromolecules and
International Congress on Recombinant DNA, p. 39. Elsevier Publishing Co.
Arking, R. (1985) Gompertz analysis of survival data obtained from 25 generations of
successful selection for increased longevity in Drosophila. The Gerontologist 25:216.
Arking, R., Wells, R., Buck S. And Prretzlaff R. (1986). Increased metabolic potential of
long lived strains of Drosophila. The Gerontologist 26 (Oct.):75A.
(The poster presentation of this abstract (#40) won my students a shared 1st prize in the
GSA’s George Sacher Student Presentation Award for 1986).
Arking, R. (1987). Letter to the Editor. Experimental Gerontology 22:223-226.
Arking, R. And Witten, M. (1987). Theoretical analysis of longevity changes in Drosophila
melanogaster. The Gerontologist 27:149A.
Pretzlaff, R. And Arking, R. (1987). Protein synthesis and aging in D. Melanogaster. The
Gerontologist 27:150A.
Buck S., Wells, R.A. And Arking, R. (1987). A biomarker of senescence and impending
death in Drosophila. The Gerontologist 27:149A.
Wells, R.A., Buck, S., Ali, R., Marzoug, O. And Arking, R. (1987). Localization of the
longevity gene in D. Melanogaster. The Gerontologist 27:149A.
The poster presentations of the above two abstracts (#44, 45) won my student a shared 1st
prize in the GSA’s George Sacher Student Presentation Award for 1987. This was
their second win in two years.
Neslund, C.M., Wells, R.A. And Arking, R. (1988). Behavioral genetic anlysis of a long lived
strain of Drosophila melanogaster. The Gerontologist 29:226A.
Baker, G.T. III and Arking, R. (1988). Biophysiologic events as markers of species specific
life spans. The Gerontologist 29:244A.
Arking, R. and Wells, R.A. (1989). On the use of functional age biomarkers in a
comparative genetic analysis of aging in Drosophila. The Gerontologist 29: 185A.
Dudas, S. and Arking, R. (1990). Genetic expression in longlived strains of Drosophila. The
Gerontologist 30:115A.
Force, A.G. And Arking, R. (1991). Comparative gene expression patterns as a
paleobiological tool in reconsructiong the history of the vertebrate limb. Argonne
Symposium for Undergraduates in Science, Argonne National Laboratory, Argonne,
IL, November 1991.
Dudas, S.P. And Arking, R. (1992). Mechanisms underlying the inducibility of extended
longevity in Drosophila. Invited poster presented at the Gordon Conference on the
Biology of Aging, August 1992.
Dudas S. And Arking, R. (1992) Genetic expression in long-lived strains of Drosophila. The
Gerontologist 32:121A.
Arking, R., Dudas, S.P., Buck, S., Force, A.G. (1993). Larval regulation of adult gene activity
and of adult longevity. 34Th Annual Drosophila Research Conference Program,
Abstract 279A.
Arking, R., Dudas, S.P., Buck, S., Force, A., Nicholson, M., and Baker, G.T., III. (1993).
Genetic and Molecular Analysis of Longevity Assuranc ce Genes in Drosohila. J.
Cellualar Biochemistry Supplement 17D:143, Abstract 012 (Keystone Symposia)
Force, A., Staples, T., and Arking R. (1993). Similar suites of physiological characters are
correlated with both long lived and short lived strains of Drosophila. The
Gerontologist 33:.
Soliman, S. And Arking, R. (1994). Antioxidant gene activity patterns and oxidative damage
in short-lived strains of Drosophila. The Gerontologist 34:
Arking, R., Ventrinno, P., Vongpunsawad, S. And Shabash, P. (1995). Separation of
enhanced antioxidant activity from extneded longevity. The Gerontologist. 35:55
Soliman, S., Saraiya, A., Wehr, N., Sedki, B., Levine, R. And Arking, R. (1996). Patterns of
paraguat resistance and oxidative damge in long lived and short lived strains of
Drosophila. The Gerontologist 36:22.
Baker, G.T. III, Buck, S., Graves, K. And Arking, R. (1996). Selection associated allelic
changes in genes supporting high levels of antioxidant resistance in long-lived strains
of Drosophila. The Gerontologist 36:205.
Burde, V., Hari, R. And Arking, R. (1996). Immunological detection of high levels of CuZU
SOD protein in long-lived Drosophila strains, The Gerontologist 36:295.
M.A. Lane, D.S. Hwangbo, E. Feldman and R. Arking . Downregulation of Insulin Signaling
Increases longevity in Drosophila. Geron. Soc. America (Biol. Sci.) October 2000.
R. Arking. Introductory Remarks. Symposium on Nutrition and Aging. Geron. Soc. America,
Nov. 1999
R. Arking, The search for genes that modulate aging in Drosophila.. Geron. Soc. America,
Nov., 1999.
Hwangbo, D-S, M. Lane and R. Arking. Synergistic interaction between the insulin signaling
system and the antioxidant defense system results in a significant longevity extension.
Geron. Soc. America, Nov. 2001.
R. Arking and C.N. Giroux. 2003. Gene networks, individual senescence, and timeless aging.
Biogerontology 4 suppl. 1:4
V. N. Novoseltsev, R. Arking, J. R. Carey, J. A. Novoselseva, and A. I. Yashin. 2003. How
an individual fecundity pattern looks in Drosophila and Medflies. Biogerontology 4
suppl. 1: 74.
H. Book Reviews 1.National/International (N=7)
An invited book review of "Evolutionary Biology of Aging" by Michael R. Rose.
Experimental Gerontology 29:225-230. 1994.
An invited book review of "Human Aging: Biological Perspective" by Augustine G.
DiGiovanna. The Gerontologist. 1995.
An invited review of "Time of Our Lives" by Tom Kirkwood. J. Anti-Aging Medicine 4:
An invited review of “The Mitochondrial Free Radical Theory of Aging” by Aubrey D.N.J.
de Grey. J. Anti-Aging Medicine 5: in press
An invited review of “Intercellular Signaling in Age-related Degenerative Diseases”, M.
Mattson (ed.). J. Anti- Aging Med. 5: in press
“ A New Age for Aging: Biological and Ethical Questions”. Review of 10th
Int. Mtg of Intern.
Assoc. Biomed. Gerontol., Sept 03. Rejuvenation Research: in press.
Arking, R. 2005. Biology, Fruit Flies, and Humans: Can Extended Longevity Stretch from
One to the Other? The Gerontologist 45:418-425. (Essay based on review of four
books)
L. Papers/Posters Presented (in additon to these compiled under "Abstracts Published"). (N=16 plus)
Genetic Analysis of Pattern Formation in Drosophila. Invited Speaker. Conference on
Mosaicism in Drosophila, University of California at San Diego, La Jolla, California-
September 1974.
Mapping of a gradient in the Drosophila leg disc by means of "genetic surgery". ICN-
UCLA Conference on Developmental Biology. 1975.
Direct selection of mutant resistant to juvenile hormone analogues. Seventeenth
Annual Drosophila Genetics Conference. 1975.
Metamorphosis of the Humeral Disc of Drosophila. Twenty-first Annual Drosophila
Genetics Conference, 1979.
Effects of Nucleotide inhibitors on the emryonic development of Drosophila. Twenty-
first Annual Drosophila Genetics Conference. 1979.
Patterns of Protein Synthesis during Embryogenesis of Drosophila. Wenty-second
Annual Drosophila Genetics Conference, 1980 and Midwest Regional Developmental
Biology Conference, 1980.
Developmental Modulation of Protein and RNA Patterns During Drosophila
Embryogenesis. Twenty-fourth Annual Drosophila genetics Conference, 1982.
The Effect of Heat Shock on Early Drosophila Embryos. Twenty-fourth Annual
Drosophila Genetics Conference, 1982.
Selection for Delayed Senescence in Drosophila. Thirty-eighth Annual Meeting.
Gerontological Society of America, 1985.
Genetic and Physiological Delieneation of Aging Pheno type: Use of Biomarkers.
Paper presented at Aging Workshop, 28th National Drosophila Research Conference,
May 1987 (note: I co-organized the workshop and chaired the session).
Force, A. And Arking, R. Comparative gene expression patterns as a paleobiological
tool in reconstructing the history of the vertebrate limb. Argonne Symposium for
Undergraduates in Science, Novemer 1991.
Baker, G.T., III and Arking, R. Theories of an intervention in the processes of aging.
The 3rd Anniversary International Symposium of Korea Gerontology Center, October
30, 193.
Arking, R., Vettraino, J., Vongpunsawad, s., and Shabash. Separtion of enhanced
antioxidant activity from extended longevity. The Gerontologist 35:55. Paper
presented 18 Nov. 1995.
2.Local/Regional Genetic analysis of Endocrine Processes. Zoecon Corporation, Palo alto, Claifornia,
March 1972.
Genetic Analysis of Pattern Formation in Drosophila melanogaster. Midwestern
Regional Developmental Biology Conference, 1976.
Developmental Effects of a New Cell Lethal Mutation. Mid-America Drosophila
Geneticists Meeting, 1978.
M. INVITED SPEAKER OR PARTICIPATION IN VARIOUS CONFERENCES:
1. National/International Meeting (N=33)
Invited Speaker and Participant in Symposium on "Determinants of Lifespan"
sponsored by the Gerontological Society of America in November l985. I presented a
talk entitled "Genetic and Environmental Determinants of Lifespan in Drosophila."
Invited Speaker and Participant in Brookhaven Symposia in Biology Number 34
"Aging Processes in Animals", held in October, 1986. I presented a talk entitled
"Genetic and Environmental Determinants of Longevity in Drosophila" which was
published as a book chapter in l987.
Invited Speaker and Participant in the Gordon Conference on the Biology of Aging
(July, l986). I presented a talk entitled "Increased Metabolic Potential in Genetically
Selected Long-Lived Strains of Drosophila."
Invited Participant in the Gordon Conference on the Biology of Aging (February,
1988). I presented a paper entitled "Localization of the Longevity Determinant Genes
of Drosophila".
Invited speaker and participant in symposium on "Changes in Genetic Mechanisms in
Aging" held as part of the XIV International Congress of Gerontology in Mexico,
June, 1989. The symposium was organized by Dr. Judith H. Ford (Australia). The
title of my talk was "Genetic Analysis of Aging Mechanisms in Drosophila".
Invited speaker and participant in symposium on "Genetic Analysis of Aging and
Longevity" held as part of the 19th Annual Meeting of the American Aging
Association, October, 1989 in Washington, D.C. The symposium was organized by
Dr. J.P. Phillips (Canada). The title of my talk is "Genetics of Aging in Drosophila:
Analysis of the Extended Longevity Phenotype".
Invited speaker and participant in Third Serling Symposium on The Biology of Aging;
Sept. 1990 in Jerusalem, Israel. The symposium was organized by Prof. Amiela
Globerson. The title of my talk was "Genetic and Molecular Analysis of the Extended
Longevity Phenotype in Drosophila".
Invited speaker and participant in symposium on "Molecular Genetics of Aging" held
in Boston, November 1990, in conjunction with the Gerontology Society of America
National meeting. The symposium was organized by Prof. J. Michael Jazwinski
(LSU). The title of my talk was "Genetic and Molecular Characterization of the
Major Life-Span Determining Loci of Drosophila."
Invited speaker and participant in symposium on "Aging and Genetic Plasticity" to be
held in San Francisco in November 1991 in conjunction with the Gerontology Society
of America National Meeting. The symposium is being organized by Dr. G.T. Baker
III (NIA). The title of my talk will be "Genetic and Environmental Regulation of
Longevity in Drosophila".
Invited speaker and co-chair of a symposium on "Molecular Genetic Mechanisms of
Aging in Drosophila" held in Washington, D. C. In November 1992 in conjunction
with the Gerontology Society of America National Meeting. My talk was entitled,
"Mechanisms underlying the inducibility of longevity in a long lived strain of
Drosophilia".
Invited speaker and participant in Keystone Symposia on "Molecular Biology of
Aging", held at Lake Tahoe in March 1993. The title of my talk was "Genetic and
Molecular Analysis of Longevity Assurance Genes in Drosophila. The symposia was
organized by T.J. Johnson and C. Finch.
Invited speaker and participant in Dahlem Workshop on Molecular Aspects of Aging,
to be held in Berlin 13-18 February 1994. The conference was organized by Karl
Esser and George Marhn. Only 3 people have been invited to this international
conference. Our task willl be to write a series of group reports to be published as a
book, which will critically review the field and offer suggestions for future research
directions.
Invited speaker and participant in the SFRR Asia/Oxygen Society Conference on
"oxidative Stress and Aging" held in Hawaii on March 22-26, 1994. The title of my
presentation was "Antioxidant Genes and Other Mechanisms Involved in the Extended
Longevity of Drosophila". The conference was organized by John Bertram, Richard
Cutler, Akitane Mori and Lester Packer.
Invited speaker and participant in Gordon Conference on The Biology of Aging. Jan.
1997. The conference wasorganized by T.E. Johnson.
Invited speaker and organizer of a symposium "Searching for Aging Genes in
Drosphilla", held at the Gerontology Society of America National Meeting in Nov.
1998.
Organized Presidential Symposium on Nutrition and Aging. Nov. 1998. Gerontology
Soc. America.
Invited speaker at a symposium entitled "Metabolic Mechanisms of Longevity:
Divergent Models, Convergent Pathways", at the American Aging Assoc. In June
1999.
Co-organized a Symposium on "New Prospects for Identifying Longevity
Mechanisms in Invertebrates" at the American Aging Assoc. Meeting in June 1999.
Invited speaker at Student Symposium of Gerontology Soc. Amer. Nov. 1999 on
"Future Advances In Biogerontology Research"
Organized the 1999 National Meeting of the Biological Sciences Section of the
Gerontology Society of America, San Francisco, Nov. 1999.
Invited speaker and participant in conference in Vascular Aging and Angiogenesis
held in Pusan, Korea 26 February 2000.
Invited Speaker at a Templeton Foundation sponsored symposium "Extended Life-
Eternal Life" which brought biologists and theologians to discuss the ethics of
longevity extension. Philadelphia, P.A., March 5-6, 2000.
Invited speaker at a NIA sponsored Seventh Annual Training Course in Aging
Research held at the University of Michigan in June 1999. The topic of my talk was
“Stress Resistance and Longevity in Drosophila”.
Invited speaker at Student Symposium of Gerontology Soc. Amer. Nov. 1999 on
"Future Advances In Biogerontology Research"
Invited speaker at the Annual Meeting of the Intern. Assoc. Biomedical Gerontology,
“Gene Expression and Regulation in the Extended Longevity Phenotypes of
Drosophila”. Kyongju, Korea. February 21-24, 2000.
Invited speaker at the Conference on Vascular Aging and Angiogenesis, “Is There a
Core Set of Antioxidant Genes Involved in Resistance to Oxidative Stress?”, Pusan
National University, Pusan, Korea, February 26, 2000.
Invited Speaker at a Templeton Foundation sponsored symposium “Extended Life-
Eternal Life” which brought biologists and theologians together to discuss the ethics
of longevity extension. Philadelphia, PA, March 5-6, 2000.
Invited speaker at at the Pusan National University Genome Center Symposium on
Human Genome Analysis, “Complex Phenotypes and Post-Genomic Analysis, Pusan
National University, Pusan, Korea, February 22, 2001.
Invited speaker at the 2nd
International Symposium on Vascular Aging and
Angiogenesis, “Multiple Responses to Cellular Stress”. Pusan National University,
Pusan, Korea. June 2, 2001
Invited speaker at the Annual Meeting of the Intern. Assoc. Biomedical Gerontology,
“Multiple Genetic Mechanisms of Extended Longevity in Drosophila” ,Vancouver,
Canada, June 26-30, 2001.
Invited speaker at the Annual Meeting of the Gerontol. Soc. America “Anti-aging
Medicine: the Hype and the Reality” (S.J. Olshansky, org.). My talk was titled “ The
human life span is not that limited: Effects of multiple longevity phenotypes”.
Washington DC, Nov. 2004
Invited keynote speaker at the WSU-UM Joint Conference of the Institutes of
Gerontology. My talk is entitled “Extending Human Longevity: Biological
Mechanisms & Societal Implications”. Detroit, MI. April 5 2005.
Invited speaker at the Fourth Stromboli Conference on Aging & Cancer, themed as the
“Reversal of Aging: Myth and Reality”. Stromboli, Italy. June 5-11, 2005. My talk
was titled “A Mechanistic View of the Transition from the Health Span to the
Senescent Span”).
Invited speaker at the 2007 Anthropology and Health Conference on Hvar Island
Croatia for the Croatian Institute for Anthropological Research.
The Conference will focus on “Evolutionary Biology,
Age-Related Disease, Cellular Senescence, and the Biodemography of
Human Longevity”. My talk will be entitled “Gene expression, mitochondria, and
extended health span in Drosophila”.
Invited speaker at the 2007 European MiMAGE (Mitochondrial Consortium) Summer
School in Switzerland in September 2007. My talk will be entitled “Gene expression,
mitochondria, and extended health span in Drosophila”.
Invited speaker at the 2007 Yukawa International Symposium, Kyoto University, on
“What is Life: The Next 100 Years of Yukawa’s Dream”. My talk will deal with a
broad overview of the biology of aging.
In addition to the above invited talks I also:
Organized two symposia for the 1998 national meeting of the Biological
Sciences Section of the Gerontology Soc. of America. held in Philadelphia,
November 1998
Organized the 1999 national meeting of the Biological Sciences Section of
the Gerontology Soc. of America held in San Francisco, November 1999.
Co-organized one symposia for the June 1999 meeting of the American
Aging Association.
2.Local or Regional Talks (N=30)
As a representative of the University, I gave a series of lectures to various adult educational
and social groups throughout the metropolitan Detroit area on the general topic of "The
Human Use of the New Genetics."(1977-1978).
Seminar Speaker - genetic Analysis of Pattern Formation in Drosophila - Departments of
Biology, Oakland University 1976; University of Detroi - May,1976; Department of
Biology, University of Detroit; Department of Biology, Central Michigan University -
1977, 1978.
Seminar Speaker - Molecular Aspects of Embryogenesis in Drosophila - Department of
Zoology, Michigan State University, 1979; department of Anatomy, Howard University,
School of Medicine, 1980;
Department of Biology, University of Nebraska at Lincoln, 1980; Department of Biology,
Hope College, 1981; Division of Life Sciences , University of Michigan, 1981
Seminarr Speaker - Genetic Analysis of Aging in Drosophila - Institute of Gerontology,
Wayne State University, 1984; Department of Biology, Hope College, 1984; Department of
Biology, McMaster University, 1985; Department of Biology, University of Michigan,
1986; Department of Biology, Central State University, 1986; Department of Biology,
University of Guelph, 1987; University of Michgan-Dearborn, 1987; Ohio Weslyan
University, 1987; Aquinas College, 1988. Gerontology Research Center, National Institute
on Aging, 1992. Institute of Gerontology, University of Michigan, 1993. Institute of
Gerontology, Wayne State University, 1993. Department of Biology, Oakland Univrsity,
1993;Department of Nutrition and Food Science, Wayne State University, 1993. Institute
of Gerontology, University of Michigan 1998. Botsford Hospital Conference on Aging
1998. NIA-NIH mini course on Biology of Aging July 1999. Department of Nutrition and
Food Science, Wayne State University, September 1999. Department of Biochemistry,
University of Louisville, Sept. 2000; Department of Food and Nutrition, Pusan Nat.
University, April 2001, Dept of Geriatrics, Beaumont Hospital, Detroit, June 2002; Dept.
of Molecular Genetics, University of Guelph, Nov 2002;
WSU-UM Institutes of Gerontology Joint Meeting, April 2005; Dept of Pharmacy,
WSU, May 10, 2005; University of Salzburg, March 2006; University of Innsbruck,
TBA 2006, University of Vienna, TBA 2006.
N. OTHER SCHOLARLY WORK Organized campus-wide "Developmental Biology Interest Group’ (1979,1980).
Co-organizer with Dr. Ann Sodja of symposium on Developmental Genetics of
Drosophila at National AAAS meeting held in Detroit, May, 1983.
Invited Participant in NIA sponsored conference on Future Directions in Biomarker
Research, November 1986.
Co-organizer (with Dr. George T. Baker III) of an Aging Workshop held as part of the
Drosophila Genetics Conference, May 20-24, 1987. This represented in part a
successful culmination of efforts by the Gerontology Society of America to encourage
mainstream genetic analyses of the aging processes. It also represented the first time
this conference had a formal session on this topic.
Co-organizer (with Mary Lou Pardue and George T. Baker, III) of a workshop entitled
"Drosophila: The Molecular-Genetic Mechanisms of Aging" which was held in
November 1992 in conjunction with the National Meeting of the Gerontology Society
of America. The goal of the workshop was to critically examine the progress and
problems made to date in understanding the molecular genetic mechanism of aging
operative in Drosophila.
Reviewer of papers having to do with genetics of aging and submitted for presentation
at th XV International Association of Gerontology Meeting in August 1993.
Chair of session entitled "Genetic Factors of Longevity", at the XV International
Association of Gerontology Meeting Budapest, August 1993 (position declined due to
lack of travel funds).
Co-organizer (with Leonard Gavrilov and Donald Ingram) of a workshop entitled
"Workshop on the Biology of Longevity in Humans and Non-Humans", which was
held in December 1996 at the Gerontology Research Center-Nat. Inst. On Aging. The
goal of the workshop was to critically analyze new data bearing on the effects of
parental longevity and age of reproduction on offspring longevity. The workshop was
funded by the U.S. Civilian Research Defense Fund.
Organized two symposia for the 1998 national meeting of the Biological Sciences
Section of the Gerontology Soc. of America. held in Philadelphia, November 1998
Organized the 1999 national meeting of the Biological Sciences Section of the
Gerontology Soc. of America held in San Francisco, November 1999.
Co-organized one symposium for the June 1999 meeting of the American Aging
Association.
IV. SERVICE
A. Adminsitrative Appointments at Wayne State None.
B. Admistrative Appointments at Other College/University Member, External Advisory Board, Biotechnology Program, Ferris State
Univ., 1991-98
C. Committee Assignments
1. University Committee Membership University Ethics Education Committee, 1987-89
Advisory Committee, Institute of Gerontology, 1987-93
Sabbatical Review Advisory Committee, 1990-91, 1996-97
Internal Review Advisory Panel, Dept. Of Nurse Anesthsia 1991
Scholarship and Fellowships Review Panel, 1992-93
Research Award Evaluation Committee 1993, 1997, 2004
Library Committee, 1993-95
University Honors Council, 1997-present
Promotion and Tenure Committee - both Faculty and Staff - 1998
Faculty Recognition Award Committee - 2002, 2004
Research Committee (AAUP liason) 2002 ff
Provost Select Committee on Student Retention, 2007
2. College Committee Membership Committee on Spring/Summer Within Load Assignment (Bio. Sci.), 1985
Chair Review Committee, 1985; 1998.
COS Undergraduate Committee, 2001- present
Merit Salary Committee, 2005-2006
Promotion & Tenure Committee, 2006-2008
3.Departmental Committees Chaired Coordinator, Molecular Biotechnology Program 1986-2000
Undergraduate Officer Sept 1993-Dec 1995; Sept 2001- present)
Chairman of an ad hoc committee charged with redesigning and updating the
Biology Department Graduate bulletin and Poster (1976,1978,1980,
1982; member 1989)
Space Officer, 1989-90 Completed space inventory and helped to prepare
estimate on which the program requests for Science Hall renovation
and the new Biology Building were initially based.
Chairman, Cell, Developmental and Neurobiology Division, 1983-85;1985-88; 2000,
2005, 07.
4. Departmental Committee Membership Member, ad hoc Blue Ribbon Task Force Charged with reviewing, improving
and implementing administrative solutions to various problems
associated with the department’s move to temporary quarter. Fall,
1988.
Standing Departmental Committees:
Graduate Committee, 1976-82; 1992-93
Undergraduate Committee, 1993-present
Seminar Committee, 1976-77
Space Committee, 1982-85
Executive Committee, 1985-86; continued on new Policy Committee, 1986-88, 1993-
94, 2000
Promotion and Tenure Committee, 1983-84, 1991-92; 1992-93; 1996-97, 2001-02
Salary Committee, 1984-85, 1997-98, 2001-02
Microbiologist Search Committee, 1989-90
Cell Biologist Search Committee, 1990-91; 1991-92; 1992-93; 1994-95; 1996-97
Curriculum Committee, 1976-1978
Prepared various reports having to do with curriculum anlysis and planning
D. Positions Held in Professional Associations Nominated by GSA Nominating Committee as one of two candidates for
President-elect, Gerontology Society of America, 2002. (I lost)
Nominated as candidate for Editor, J. of Gerontology: Biol. Sci. 2006 (I
declined the honor since it was not what I wanted to do)
Chair, Biological Sciences Section, Gerontology Society of America 1997-
2000.
(Served on the Executive Council for three years; scheduled the 1998 National
Meeting and organized the national meeting in 1999).
Member, Membership Committee, Biological Sciences Section, Gerontology
Society of America 1990-91; 2000-2003.
Member, Fellowship Committee, Biological Sciences Section, Gerontology
Society of America 1991-present
Asked to serve as Mentor to Student Section, Gerontology Society of America
1990-91
Organized conferences and workshops for various professional organizations
(see entry under "Other Scholarly Work").
F. Professional Consultations
NIH Special Study Section Minority Dissertation Proposals on Drosphilia Aging
1997.
National Review Panel, American Federation for Aging Research
Ad hoc grant reviewer: NIA, NSF, University of Michigan, University of Florida,
Tenure reviews for: University of Michigan, Michigan State University, University of
Connecticut, University of West Virginia, University of Richmond,
G. Journal/Editorial Activities (list journals and dates)
Editorial Board member, Rejuvenation Research 1997-present
Book review editor; Journal of Anti-Aging Medicine 1999-2002
Ad hoc reviewer for Genetics, Developmental Genetics and Developmental Biology (1976-83).
Ad hoc reviewer for Gerontology, Exp. Gerontology, Mechanisms of Ageing & Develop, J.
Gerontology: Biol. Sciences, Biogerontology, Pesticide Biology, Toxicology &
Pesticides., Insect Physiology, J. Physiology: Endocrine.
Ad hoc reviewer for NSF Developmental Biology Program (1973-88), NSF Genetic Biology
Program (1995- present); NIH Biology of Aging Program (1997 - present); Univ. of
South Florida Research Program (1999)
Ad hoc manuscript reviewer for Oxford University Press, Academic Press, Princeton
University Press, Michigan Academy of Science, Arts and Letters.
Other Professionally Related Service (Please Specify)
As a representative of the University, I gave a series of Lectures to various adult education
and social groups throughout the Metropolitan Detroit area on the general topic of "The
Human Use of the New genetics". 1977-78.
As a representative of the University , I have spoken at various freshman recruitment events
sponsored by the Admission Office (ca 1980-87).
Faculty Advisor; Biological Sciences Graduate Student Association, 1983-85