OFFICIAL JOURNAL OF THE CONTROLLED RELEASE SOCIETYAND THE JAPANESE SOCIETY OF DRUG DELIVERY SYSTEM

VOLUME 169, ISSUES 1– 2, 10 – 28 JULY 2013 ISSN: 0168-3659

COVER STORYJust getting into cells is not enough

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Vol. 169, Issues 1–2 JOURNAL OF CONTROLLED RELEASE 10 – 28 JULY 2013

CONTENTS

Cited in: BIOSIS/Biological Abstracts; CAB Abstracts; Chemical Abstracts Services; Current Contents (Life Sciences); EMBASE/Excerpta Medica; International Pharmaceutical Abstracts; PUBMED/MEDLINE/Index Medicus; Polymer Contents; Science Citation Index. Also covered in the abstract and citation database SciVerse Scopus®. Full text available in SciVerse ScienceDirect ®

Available online at www.sciencedirect.com

05054

Cover Story Just getting into cells is not enough

K. Park (West Lafayette, USA) 162

Reviews Layered double hydroxides as drug carriers and for controlled release of non-steroidal antiinfl ammatory drugs (NSAIDs): A review

V. Rives , M. del Arco and C. Martín ( Salamanca, Spain ) 28 Recent advances in theranostic nanocarriers of doxorubicin based on iron oxide and gold nanoparticles

J. Gautier , E. Allard-Vannier , E. Munnier , M. Soucé and I. Chourpa (Tours, France ) 48 Thermosensitive liposomes for localized delivery and triggered release of chemotherapy

T. Ta and T.M. Porter (Boston, USA ) 112 Liberation of drugs from multi-wall carbon nanotube carriers

S. Boncel , P. Zajac and K.K.K. Koziol (Gliwice, Poland; Cambridge, UK ) 126

Research Papers Ethanol-resistant polymeric fi lm coatings for controlled drug delivery

Y. Rosiaux , S. Muschert , R. Chokshi , B. Leclercq , F. Siepmann and J. Siepmann (Lille, France; Brussels, Belgium; Ewing, USA ) 1 Synergistic targeting/prodrug strategies for intravesical drug delivery — Lectin-modifi ed PLGA microparticles enhance cytotoxicity

of stearoyl gemcitabine by contact-dependent transfer L. Neutsch , E.-M. Wirth , S. Spijker , C. Pichl , H. Kählig , F. Gabor and M. Wirth ( Vienna, Austria ) 62

Intra-articular drug delivery from an optimized topical patch containing terifl unomide and lornoxicam for rheumatoid arthritis treatment: Does the topical patch really enhance a local treatment? H. Xi , D. Cun , R. Xiang , Y. Guan , Y. Zhang , Y. Li and L. Fang (Shenyang, China ) 73

SPECT/CT imaging of temperature-sensitive liposomes for MR-image guided drug delivery with high intensity focused ultrasound M. de Smet , S. Langereis , S. van den Bosch , K. Bitter , N.M. Hijnen , E. Heijman and H. Grüll (Eindhoven, Netherlands ) 82

Cell-free carrier system for localized delivery of peripheral blood cell-derived engineered factor signaling: towards development of a one-step device for autologous angiogenic therapy E. Hadjipanayi , A.T. Bauer , P. Moog , B. Salgin , H. Kuekrek , B. Fersch , U. Hopfner , T. Meissner , A. Schlüter , M. Ninkovic , H.G. Machens and A.F. Schilling ( Munich, Düsseldorf, Germany ) 91

Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood–tumor and blood–brain barriers improve outcomes in a rat glioma model M. Aryal , N. Vykhodtseva , Y.-Z. Zhang , J. Park and N. McDannold (Chestnut Hill, Boston, USA ) 103

Development and evaluation of novel solid nanodispersion system for oral delivery of poorly water-soluble drugs P. Nkansah , A. Antipas , Y. Lu , M. Varma , C. Rotter , B. Rago , A. El-Kattan , G. Taylor , M. Rubio and J. Litchfi eld ( Groton, West Lafayette, USA ) 150

Gene Delivery Cavitation-enhanced delivery of a replicating oncolytic adenovirus to tumors using focused ultrasound

M. Bazan-Peregrino , B. Rifai , R.C. Carlisle , J. Choi , C.D. Arvanitis , L.W. Seymour and C.C. Coussios (Oxford, UK; Barcelona, Spain) 40

Nanomedicine A new potential nano-oncological therapy based on polyamino acid nanocapsules

T. Gonzalo , G. Lollo , M. Garcia-Fuentes , D. Torres , J. Correa , R. Riguera , E. Fernandez-Megia , P. Calvo , P. Avilés , M.J. Guillén and M.J. Alonso ( Santiago de Compostela, Madrid, Spain ) 10

(Contents continued at inside back cover)