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OFFICIAL JOURNAL OF THE CONTROLLED RELEASE SOCIETYAND THE JAPANESE SOCIETY OF DRUG DELIVERY SYSTEM

VOLUME 204, 28 APRIL 2015 ISSN: 0168-3659

COVER STORYThin-film freeze-drying for lyophilization of vaccines

Vol. 204 JOURNAL OF CONTROLLED RELEASE 28 APRIL 2015

CONTENTS

Cited in: BIOSIS/Biological Abstracts; CAB Abstracts; Chemical Abstracts Services; Current Contents (Life Sciences); EMBASE/Excerpta Medica; International Pharmaceutical Abstracts; PUBMED/MEDLINE/Index Medicus; Polymer Contents; Science Citation Index. Also covered in the abstract and citation database Scopus®. Full text available in ScienceDirect ®

Available online at www.sciencedirect.com

05054

Editorial

EditorialK. Park A1

Cover Story Thin-film freeze-drying for lyophilization of vaccines

K. Park (West Lafayette, USA) 98

Review Radio frequency responsive nano-biomaterials for cancer therapy

N.S. Rejinold , R. Jayakumar and Y.-C. Kim ( Daejeon, Republic of Korea; Kochi, India ) 85

Research Papers Sponge-mediated lentivirus delivery to acute and chronic spinal cord injuries

A.M. Thomas , J.L. Palma and L.D. Shea ( Evanston, Illinois; Evanston, Chicago, USA) 1 Macrophage mediated biomimetic delivery system for the treatment of lung metastasis of breast cancer

J. Fu , D. Wang , D. Mei , H. Zhang , Z. Wang , B. He , W. Dai , H. Zhang , X. Wang and Q. Zhang ( Beijing, China ) 11 Laser mimicking mosquito bites for skin delivery of malaria sporozoite vaccines

C. Zhou , X. Chen , Q. Zhang , J. Wang and M.X. Wu ( Boston, Cambridge, USA ) 30 A method of lyophilizing vaccines containing aluminum salts into a dry powder without causing particle aggregation or

decreasing the immunogenicity following reconstitution X. Li , S.G. Thakkar , T.B. Ruwona , R.O. Williams III and Z. Cui ( Austin, USA ) 38

Oil and drug control the release rate from lyotropic liquid crystals I. Martiel , N. Baumann , J.J. Vallooran , J. Bergfreund , L. Sagalowicz and R. Mezzenga ( Zurich, Lausanne, Switzerland ) 78

Gene Delivery Kinome-level screening identifies inhibition of polo-like kinase-1 (PLK1) as a target for enhancing non-viral transgene expression

M.D. Christensen , J.J. Elmer , S. Eaton , L. Gonzalez-Malerva , J. LaBaer and K. Rege ( Tempe, USA ) 20

Nanomedicine Dendrimer-like alpha- D -glucan nanoparticles activate dendritic cells and are effective vaccine adjuvants

F. Lu , A. Mencia , L. Bi , A. Taylor , Y. Yao and H. HogenEsch ( West Lafayette, USA ) 51 Multiple sessions of liposomal doxorubicin delivery via focused ultrasound mediated blood–brain barrier disruption: A safety study

M. Aryal , N. Vykhodtseva , Y.-Z. Zhang and N. McDannold ( USA ) 60 Evaluation of drug loading, pharmacokinetic behavior, and toxicity of a cisplatin-containing hydrogel nanoparticle

M.P. Kai , A.W. Keeler , J.L. Perry , K.G. Reuter , J.C. Luft , S.K. O'Neal , W.C. Zamboni and J.M. DeSimone ( Raleigh, Chapel Hill, USA ) 70

Graphical Abstracts Contents Listing $doi: 10.1016/S0168-3659(15)00192-3 e1

Calendar I

Additional material available online.