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ACKNOWLEDGEMENT

I would like to express my sincere gratitude and heartfelt thanks to my

supervisor Dr. S.M. Shanta Kumar, Principal V.L. College of Pharmacy, Raichur,

for his guidance, advice, kind cooperation, constant encouragement and support to

complete my thesis successfully.

I wish to express my sincere gratitude and respectful thanks to my co-

supervisor Dr. N. Rama Rao, Prof. & Principal, Chalapathi Institute of

Pharmaceutical Sciences, Guntur, for his invaluable guidance, ideas and continuous

support to carryout this research work.

I am very much indebted to my beloved husband, Dr. K.M.K. Swamy,

Professor, Dept of Pharmaceutical Chemistry, V.L. College of Pharmacy, Raichur, for

his help, intellectual support and constant encouragement throughout the way in

completing this thesis. Without his source of inspiration, cooperation, moral support

and freedom of work to complete this thesis, it wouldn’t have seen the light of day.

I express my deep sense of gratitude and heartful thanks to Dr. Y. Anand

Kumar, Prof and HOD, Dept. of Pharmaceutics, for his help, keen interest, valuable

suggestions and shared intelligent thoughts during my thesis work.

It is my pleasure to thank Dr. V. Hemanth Kumar, Vice-Principal, Dr. N.

Venkat Rao, Dr. Pramod Kumar, Dr. N. Shrinivasulu, Dr. Rajeeva, and

Zahherruddin V.L. College of Pharmacy, Raichur, for their help and good wishes

during the course of the study.

I cordially thank Dr. Laxmayya and Dr. Somashekar Shyale for their help

and valuable suggestions. My special thanks to Smt. V.L. Patil, Prof. A.M.E’s Dental

College, Raichur, for her warm wishes and encouragement to complete my research

work.

Thanks to my colleagues Mrs. Hafsa Mohammedi and Mr. Manish for their

good wishes. I also thank Dr. Sunil, Smt. Pradnya Patil, NET College of Pharmacy,

Raichur for their kind cooperation.

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I thank Dr. Juyoung Yoon, Prof. Department of Chemistry, EWHA Woman’s

University, Seoul, South Korea for providing NMR data. I would like to thank Dr.

Vithal Jadhav and Dr. Rekha Jadhav for helping me in getting DSC studies.

I express my sincere gratitude and heartfelt thanks to my father-in-law Shri.

K.M. Shankaraiah, mother-in-law Smt. K.M. Kotramma, father Shri. K.M.

Vamadevaiah, mother Smt. K.M. Vimaladevi without whose blessings and

encouragement it would not have been possible to complete my research work.

I owe special thanks to my brother-in-laws K.M. Halaswamy, K.M. Ajjaiah,

co-sisters, brothers K.M. Vageesh, K.M. Basavaraj, sisters Smt. Veeramma, Smt.

Bharathi and all the family members for their good wishes, help and encouragement

during the course of my study.

It is a pleasant aspect to express my profound, evergreen love and thanks to

my children Master K.M. Anoop Swamy and Master K.M. Swaroop Swamy whose

understanding and cooperation made this work possible. Their love and tolerance

served as a source of inspiration, strength, and determination at each and every front

of my life.

Finally, I would like to thank all the teaching and non-teaching staff of V.L.

College of Pharmacy for their help during my research work.