Ageless Bio-OptimaAgeless Bio-Optima The Intelligent Nutrient The Intelligent Nutrient

Presented by Nicole YowUniversity of Guelph, Canada (Bachelor of Food Science)

Hovid Marketing Sdn BhdAgeless Bio-Optima

200-300% Better

Absorption

Hovid’s MilestoneHovid’s Milestone• Started as a Herbal tea stall by Dr. Ho Kai Cheong, the founder of Ho Yan Hor® herbal Tea

• Hovid transformed into a Pharmaceutical manufacturing company by Mr. David Ho.• Quality, reliable and innovative OTC & ethical drugs

Ageless Bio-Optima

Today’s HovidToday’s Hovid Listed on the Main Board of Kuala Lumpur Stock Exchange Manufacture more than 300 products and export to over 40

countries around the world.CanadaUSAHaitiPanamaPeruChileUKDenmark

GhanaNigeriaMaltaSudanKenyaIraqYemenSri Lanka

AfghanistanKoreaHong KongTaiwanVietnamMyanmarCambodiaThailand

PhilippinesBruneiPapua New GuineaFijiAustraliaAnd more…

Ageless Bio-Optima

Mr. David HoMr. David HoManaging Director Managing Director Hovid Berhad and Carotech Hovid Berhad and Carotech BerhadBerhad

• Director of Malaysia Biotechnology Corporation  (BioTechCorp)

• Member of Malaysia Biodiesel Association (MBA)

• Member of Malaysian Organization of Pharmaceutical Industries (MOPI)

• Member of Malaysian Pharmaceutical Society (MPS)

• Member of International Society for Pharmaceutical Engineering (ISPE)

• Member of The Royal Pharmaceutical Society of Great Britain (RPSGB)         

• Member of Pharmaceutical Society of New Zealand (PSNZ)

Ageless Bio-Optima

Two Pillars of Hovid – Two Pillars of Hovid – RESEARCH AND DEVELOPMENT RESEARCH AND DEVELOPMENT

Achievements• FIRST in the world to develop process for extracting valuable

tocotrienols from palm oil• FIRST in the world to develop the self-emulsifying “Bio-Optima”

System• FIRST in Malaysia to produce effervescent tablets• FIRST in Malaysia to produce antibiotics in dispersible tablet form

• More than 30 dedicated and highly qualified in-house research scientists including several PhD holders in Hovid Chemor and USM, Malaysia.

• In collaboration with Ohio State University Medical Center, USA Kyoto University, Japan National University of Malaysia Malaysian Palm Oil Board

Ageless Bio-Optima

Certificate of Accreditation for Laboratory

Halal Certificates from JAKIM and HDC

Safety and Quality Assurance

Ageless Bio-Optima

Ageless Bio-OptimaAgeless Bio-OptimaThe innovative product from Hovid, with 2 patents involved and has won the Product Innovation Award from

MITI.

Ageless Bio-Optima

Unlimited Health Benefits of Unlimited Health Benefits of Ageless Ageless Acne Ageing Allergies Arthritis Cardiovascular Health Cataract Cancer (breast cancer) Diabetes related symptoms Fatigue Gangrene Hair Growth Heart disease High cholesterol High blood pressure

Immune function Infections Inflammation Liver Macular degeneration Muscle recovery Neuroprotection Prostate, Scar healing Skin problems Sports endurance &

recovery Tumor UV protection

Ageless Bio-Optima

Do you know how many people die of cardiovascular diseases

worldwide annually?

Answer: 1,720,000 people

Ageless Bio-Optima

Know a little about Know a little about atherosclerosisatherosclerosis

Most common cause of heart attack/stroke

Gradual process by which plaques (fat, cholesterol, calcium, etc.) are deposited in the walls of arteries

Formation of plaqueHardening and narrowing of

arteryReduced blood and oxygen

When plaque ruptures or breaks off

Heart attack

or

Ageless Bio-Optima

Atherosclerosis - strokeAtherosclerosis - stroke

Atherosclerosis can begin as early as the teenage years, but symptoms usually do not arise until later in adulthood.

Ageless Bio-Optima

Causes of AtherosclerosisCauses of AtherosclerosisHigh LDL (bad cholesterol) >100mg/dL.

LDL- vehicle that carries cholesterol in the blood

High blood pressureLack of physical activityTobacco smokeExcessive alcoholObesity

Ageless Bio-Optima

Tocotrienol (T3) & Cardiovascular Tocotrienol (T3) & Cardiovascular HealthHealth

Tocotrienols helps to reduce the risk of heart attack and stroke by 6 ways:

1. Reduces the size of plaque, thus increase the blood flow2. Lowers bad cholesterol (LDL) in body (liver)3. Lowers blood pressure4. Reduces arterial stiffness5. Inhibits the production of adhesion molecules6. Inhibits platelet cells aggregation

PlaqueAgeless Bio-Optima

T3- Powerful AntioxidantT3- Powerful Antioxidant

Tocotrienol is 40-60 times better than tocopherol, the more commonly known vitamin E in neutralizing free radicals.

Free radicals are “bad guys” that initiate many diseases and cancers.

Ageless Bio-Optima

What are free radicals?What are free radicals?

1

1a. Normal Oxygen Atom

1

1b. Unstable atom with an unpaired electron.

2. When the attacked molecule loses its electron, it becomes a free radical itself ! This begins a chain reaction.

Non-stop and cause damage to body

3Itself becomes a free radical

2

1c. Steal electron from nearest molecule to gain stability.

Ageless Bio-Optima

Sources of Free RadicalsSources of Free RadicalsFree radicals are generated from:

Internally • Internal by-product produced during oxygen

metabolism, energy production, etc. (i.e. breathing, drinking, eating)

Externally• Diet (high fat, salt, processed food, etc.)• Lifestyle (insufficient sleep, irregular meal, etc.)• Environmental stimuli (pollution, radiation, sun

exposure, nitrous oxide, pesticides, etc.)• Drugs , cigarette and alcohol • Stress

Ageless Bio-Optima

Role of antioxidantRole of antioxidant

1

Antioxidant functions by donating an electron to stabilize the free radical and stop the damage.

Tocotrienol is 40-60 times much stronger than normal vitamin E (tocopherol) in scavenging free radicals.

2 3

1 2 3Antioxidante.g. Tocotrienol

Free Radical

Ageless Bio-Optima

T3 protects brain cells from free radical damage that leads to Alzheimer’s and Parkinson’s disease.

T3 reduces brain damage in stroke patient and promote faster recovery.

T3- NeuroprotectionT3- Neuroprotection

Ageless Bio-Optima

One of The Biggest Fear of One of The Biggest Fear of Women-Women-Breast CancerBreast Cancer

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Tocotrienol- Anti-CancerTocotrienol- Anti-CancerPrevention

Preventing oxidative damage to DNA which may lead to gene mutation and become cancerous cells

Inhibition on the Growth of Cancer Cells Inhibit the delivery of nutrients and oxygen to the

cancer cells Without nutrients and oxygen, cancer cells eventually

die off

XAgeless Bio-Optima

5 years Human Clinical Study (Breast 5 years Human Clinical Study (Breast cancer) cancer) Co-ordinated with Malaysia Palm Oil Board (MPOB) 240 women with Stage 1 Breast Cancer

Tamoxifen + Placebo

Tamoxifen + T3

Subjects involved

120 120

Survival Rate 94% 98%Recurrence Rate

18% 12%

Ageless Bio-Optima

Tocotrienol- Promote hair growth Tocotrienol- Promote hair growth and prevent hair lossand prevent hair loss

• 28 volunteers, mild to moderate severe on-going hair loss

• Volunteers received either tocotrienols (50mg, twice daily) or placebo for 8 months

• T3 supplemented group showed an average of 41.8% increase in the number of hair

Ageless Bio-Optima

A A new US patent (Patent No. new US patent (Patent No. 7,211,274)7,211,274) has been granted for has been granted for Ageless as a hair growth formulation Ageless as a hair growth formulation that increases number of hair and that increases number of hair and prevents hair lossprevents hair loss

Ageless Bio-Optima

Tocotrienol – Anti-agingTocotrienol – Anti-aging 40 years old (chronological age) but enjoy the mental and

physical youthfulness of a 30 years old (biological age)?! Harmful ultraviolet (UV) can cause dark spot, pigments,

wrinkles, fine lines, sagging skin, dull, pre-mature ageing skin and even skin cancer.

Wrinkles Sagging chin Dry, wrinkled handAge spot

Ageless Bio-Optima

Tocotrienol – Anti-agingTocotrienol – Anti-agingT3 is also incorporated into “REDEMPTION”- the 1st Skin

Care products in Malaysia which contains super vitamin E, tocotrienol.

Provide double protection

Ageless Bio-Optima

Tocotrienol in Ageless Bio-Tocotrienol in Ageless Bio-OptimaOptima Each softgel of Ageless contains 50mg of

Tocotrienol

Extracted from palm fruit via a patented molecular distillation process (US patent no. 5,157,132) with ultra-high vacuum, super low temperature. No chemical solvent is used!

Ageless Bio-Optima

For a drug to act orally, it must For a drug to act orally, it must first be absorbed!first be absorbed!

absorption

elimination

Ageless Bio-Optima

Patented Bio-Optima Delivery Patented Bio-Optima Delivery SystemSystem(US Patent No. 6,596,306)(US Patent No. 6,596,306)After gentle agitation

Normal vitamin E

formulation

Bio-OptimaDelivery System

A layer of oil floating on top

Self-emulsified

Ageless Bio-Optima (on the right) emulsifies and ensures a rapid and consistent transport of tocotrienols into the blood up to 300%.

No dietary fat is required; suitable for people who has limited fat intake in their diet. Ageless Bio-Optima

Ageless Bio-OptimaAgeless Bio-OptimaThe Intelligent Nutrient

Ageless Bio-Optima consists of 50mg of natural mixed tocotrienols, carotenoids (alpha & beta), phytosterols and plant squalene is clinically proven to :

Powerful antioxidant (40-60 times better than tocopherol)

Reduces the risk of heart attack and stroke Provides neuroprotection Anti-cancer Promote hair growth Anti-ageing And more…

Ageless Bio-Optima

For more product information, please log on to www.tocotrienol.org

Thank you!

Ageless Bio-Optima