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Lecture 2 Basics: Bonds and polarity Vocabulary: Ionic bond Covalent bond Hydrogen bond Bonding capacity Electronegativity Polar / Nonpolar Hydrophobic / Hydrophilic Solvent / solute Dissolution/Solubility 7.1 Types of chemical bonds: _______________ _________________ ________________ 7.2 Ionic bonds Formed between: Lecture 2 Page1

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Lecture 2 Basics: Bonds and polarity

Vocabulary:

Ionic bond

Covalent bond

Hydrogen bond

Bonding capacity

Electronegativity

Polar / Nonpolar

Hydrophobic / Hydrophilic

Solvent / solute

Dissolution/Solubility

7.1 Types of chemical bonds:

_______________ _________________ ________________

7.2 Ionic bonds

Formed between:

Bonds form:

7.3 Covalent bonds and polarity

Forms when:

Bonding capacity:

Electronegativity:

Covalent bonds form molecules:

Polar covalent bonds:

Examples of polar and nonpolar molecules:

Hydrogen

Oxygen

Water

Methane

7.4 Hydrogen bonds

Defined as:

7.5 Results of hydrogen bonding:

Cohesion:

Water is a solvent:

Hydrophilic vs Hydrophobic molecules:

7.6 Polarity in a cell – the plasma membrane

Lipid Bilayers

Lecture 2 Class Notes

Activity 1: (this page intentionally left blank)

Activity 2:

Molecule

P/NP/A

Why?

O – C – O

H – O – H

Functional Group

Structure

P/NP and why

Hydroxyl

Carbonyl

Carboxyl

Amino

Sulfhydryl

Phosphate

Methyl

Activity 3: Properties of a membrane protein - aquaporins

Aquaporins are channels that allow water to cross the plasma membrane. The diagram shows that aquaporins form tetramers (groups of four, doi:10.1038/ncpendmet0980). Describe what parts of the aquaporin channel protein are likely to have nonpolar functional groups.

The image (shown in class) shows a cross-section through a single aquaporin channel (Nature 407, 599-605 (5 October 2000) | doi:10.1038/35036519):

Are water molecules able to maintain hydrogen bonding as they travel through the channel? Why is this important?

What does the asparagine (Asn) do?

How is the asparagine maintained in the protein, given its location in the membrane?

Lecture 2 Page1

Lecture 2

Page

1

Lecture

2

Basics:

Bonds and polarity

Vocabulary:

Ionic bond

Covalent bond

Hydrogen bond

Bonding capacity

Electronegativity

Polar / Nonpolar

Hydrophobic / Hydrophilic

Solvent / solute

Dissolution/Solubility

7

.1

Types of chemical bonds:

_______________

_________________

________________

7.2 Ionic bonds

Formed between:

Lecture 2 Page1

Lecture 2 Basics: Bonds and polarity

Vocabulary:

Ionic bond

Covalent bond

Hydrogen bond

Bonding capacity

Electronegativity

Polar / Nonpolar

Hydrophobic / Hydrophilic

Solvent / solute

Dissolution/Solubility

7.1 Types of chemical bonds:

_______________ _________________ ________________

7.2 Ionic bonds

Formed between: