understanding cancer and related topics understanding nanodevices developed by: jennifer...
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Understanding Cancer and Related Topics
Understanding Nanodevices
Developed by:Jennifer Michalowski, M.S.Donna Kerrigan, M.S.Jeanne KellyBrian HollenExplains nanotechnology and its potential to improve cancer detection, diagnosis, and treatment. Illustrates several nanotechnology tools in development, including nanopores, quantum dots, and dendrimers.
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What Is Nanotechnology?
NanodevicesNanoporesDendrimersNanotubesQuantum dotsNanoshells
Tennis ballA periodWhite blood cell
Water molecule
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Nanotechnology Plays by Different Rules
Normal Scale Nanoscale
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Designing Nanodevices for Use in the Body
Too BigToo Small
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Manufacturing Nanodevices
Scattered X-rays
Atoms in crystal
Detector
NanodevicesCrystal White blood cell
CrystalX-ray beam
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Nanodevices Are Small Enough to Enter Cells
Cell
White blood cell
Water molecule
Nanodevices
Nanodevices
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Nanodevices Can Improve Cancer Detection and Diagnosis
ImagingNanotechnology Physical Exam,Symptoms
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Nanodevices Can Improve Sensitivity
and determinewhich cells arecancerous orprecancerous.
Precancerous cells
Normal cells
Nanodevices could potentiallyenter cells
Precancerous cells
Normal cells
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Nanodevices Can Preserve Patients’ Samples
Cells from patientCells preserved
Active state preserved
Cells altered Active state lost
Additional tests
Cells from patient
Nanotechnology Tests
Traditional Tests
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Nanodevices Can Make Cancer TestsFaster and More Efficient
Patient A Patient B
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Cantilevers Can Make Cancer TestsFaster and More Efficient
Cancer cell
Watermolecule
NanodevicesCantilevers
Antibodieswith proteins
Antibodies
Whiteblood cell
Bent cantilever
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Nanopores
ASingle-strandedDNA molecule
Single-strandedDNA molecule
Whiteblood cell
Watermolecule
NanodevicesNanopores
Single-strandedDNA molecule
ATCGNanopore Nanopore
Nanopore
T
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Nanotubes – Marking Mutations
Cancer cell
Watermolecule
Cancer-associatedchanges are tagged with bulkymolecules.
Bulky molecule tag
MutationDNA
Whiteblood cell
NanodevicesBulky molecule tag
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Nanotubes – Mapping Mutations
A nanotubetraces theshape of theDNA and makes a map.
Nanotube
White blood cell
Watermolecule
NanodevicesNanotube
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Quantum DotsUltraviolet
light off
Whiteblood cell
Watermolecule
NanodevicesQuantum dots
Quantum dots emit light
Ultravioletlight on
Quantumdots
Quantum dotbead
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Quantum Dots Can Find Cancer Signatures
Cancer cells
Healthy cells
Quantum dot beads
Quantum dot beads
Healthy cells
Cancer cells
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Improving Cancer TreatmentNanotechnology TreatmentTraditional Treatment
Intact noncancerous cells
Noncancerous cells
Toxins Nanodevices
Cancercells
Dead noncancerous cells
Noncancerous cells
Drugs
Deadcancercells
Deadcancercells
ToxinsCancercells
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Nanoshells
Nanoshell
Whiteblood cell
Watermolecule
Nanodevices Nanoshells
Gold
Near-infrared light onNear-infrared light off
Nanoshell absorbs heat
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Nanoshells as Cancer TherapyNanoshells
Dead cancer cells
Nanoshells
Cancer cells
Healthy cells
Intact healthy cells
Near-infrared light
Healthy cells
Cancer cells
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Nanodevices as a Link BetweenDetection, Diagnosis, and Treatment
Nanodevice
Reporting
TargetingDetection
Imaging
NanotechnologyCancer Treatment
Cancer cell
TraditionalCancer Treatment
Cancer cell
Drug
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Dendrimers
Dendrimer
Whiteblood cell
Watermolecule
Nanodevices Dendrimer
Cancer cell
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Dendrimers as Cancer Therapy
Cell deathmonitor
Reporter
Therapeuticagent
Cancerdetector
Watermolecule
Whiteblood cell
Nanodevices Dendrimer
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Nanotechnologies in Patient Care
Today 2020
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