tru face essence ultra ethocyn tel-aviv, israel november, 9 th 2011 tru face essence ultra

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Tru Face Essence Ultra Tru Face Essence Ultra Ethocyn Ethocyn Tel-Aviv, Israel Tel-Aviv, Israel November, 9 November, 9 th th 2011 2011 Tru Face™ essence ULTRA

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Page 1: Tru Face Essence Ultra Ethocyn Tel-Aviv, Israel November, 9 th 2011 Tru Face essence ULTRA

Tru Face Essence Ultra Tru Face Essence Ultra EthocynEthocyn

Tel-Aviv, IsraelTel-Aviv, Israel

November, 9November, 9thth 2011 2011

Tru Face™ essence ULTRA

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EthocynEthocyn® ® Tru Face Essence UltraTru Face Essence UltraRETURN TO FIRMRETURN TO FIRM

A novel, proprietary ingredient specific to increasing the important elastin fiber production in skin.

Chantal BurnisonBiochemistMedically and scientifically published inventor

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Chantal BurnisonChantal Burnison

• BiochemistBiochemist• InventorInventor• AttorneyAttorney

Areas of Study:Areas of Study:• Cell PhysiologistCell Physiologist• BiochemistryBiochemistry• AttorneyAttorney

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Tru Face™ essence ULTRA

CV at www.chantalburnison.com CV at www.chantalburnison.com

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Presentation Contentswww.ethocyninfo.com

• Research and Development of Ethocyn Molecule

• The $20mm Safety and Efficacy Testing of Ethocyn

• Results of Medically Published Ethocyn Clinical Trials

• Ethocyn for Firmer, Smoother, More Beautiful Skin.

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How Ethocyn WorksHow Ethocyn WorksUnique cosmetic ingredient in TFEUUnique cosmetic ingredient in TFEU19 years and $20+ in research and19 years and $20+ in research anddevelopment. A topical, safe and development. A topical, safe and efficacious non steroidal anti-androgen.efficacious non steroidal anti-androgen.that penetrates to the dermisthat penetrates to the dermiscausing fibroblast cell to make elastin at 20 year old youth causing fibroblast cell to make elastin at 20 year old youth

levels.levels.

Research and development of Ethocyn moleculeResearch and development of Ethocyn molecule

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Ethocyn World Testing Centers

Works on:• all skin ethnicities• male and female• > than 25 years of age

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Patents Issued/Pending Around the WorldPatents Issued/Pending Around the WorldPatentsPatents• Composition of matterComposition of matter• ProcessProcess• UseUse

TradeTrade SecretsSecrets• Isomeric compositionIsomeric composition• Stereo specific synthesisStereo specific synthesis• Exo- and endo- ratio studiesExo- and endo- ratio studies• IND (investigation of new drug) submissionsIND (investigation of new drug) submissions

TrademarksTrademarks• Ethocyn®Ethocyn®

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Ethocyn Scientific & Medical PublicationsEthocyn Scientific & Medical Publications

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The Ethocyn MoleculeThe Ethocyn Molecule

• Over $20 million and over Over $20 million and over 19 years of research and 19 years of research and developmentdevelopment

• Small Mwt. 266, lipophilic Small Mwt. 266, lipophilic moleculemolecule

• Non-steroidal target tissue Non-steroidal target tissue DHT-receptor blockerDHT-receptor blocker

• Passive diffusion to dermis Passive diffusion to dermis (C14) transdermal (C14) transdermal penetration studiespenetration studies

• Safe (44 studies; 5 species) Safe (44 studies; 5 species) • Efficacious DHT receptor Efficacious DHT receptor

blocker (competitive blocker (competitive inhibition)inhibition)

EthocynEthocyn

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EthocynEthocyn is Unique, Safe and Clinically Efficaciousis Unique, Safe and Clinically Efficacious

• No other cosmetic ingredient in the world treats skin aging (skin laxity and wrinkling) No other cosmetic ingredient in the world treats skin aging (skin laxity and wrinkling) in this important wayin this important way

• Ethocyn is a proven safe and efficacious, small mwt. non steroidal anti androgenEthocyn is a proven safe and efficacious, small mwt. non steroidal anti androgen• TFEU: Formulation that has optimally combined Ethocyn at its clinically proven MTD TFEU: Formulation that has optimally combined Ethocyn at its clinically proven MTD

(maximum therapeutic dose) with extraordinary, moisturizers, antioxidants, mmp (maximum therapeutic dose) with extraordinary, moisturizers, antioxidants, mmp inhibitors, and collagen boosting ingredients.inhibitors, and collagen boosting ingredients.

• Ethocyn is a unique, patented firming ingredientEthocyn is a unique, patented firming ingredient• Ethocyn firms lax, wrinkled skin by increasing important skin elastin fibers contentEthocyn firms lax, wrinkled skin by increasing important skin elastin fibers content• Elastin fibers are the skin’s “rubber bands”Elastin fibers are the skin’s “rubber bands”

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It is important to have young skin levels of elastin fibers It is important to have young skin levels of elastin fibers

•The skin is comprised of collagen and elastin fibers. The skin is comprised of collagen and elastin fibers.

• Collagen fibers are the structural fibers of the skin. They do not stretch well.Collagen fibers are the structural fibers of the skin. They do not stretch well.

• Elastin fibers are the important “youth protein” fibers of skin. They give skin “snap back” elasticity.Elastin fibers are the important “youth protein” fibers of skin. They give skin “snap back” elasticity.

• Young skin is abundant in elastin fibers. As we age elastin fiber content decreases. Young skin is abundant in elastin fibers. As we age elastin fiber content decreases.

• Remember: Our skin’s elastin fibers are what give skin its retraction and snap. Remember: Our skin’s elastin fibers are what give skin its retraction and snap.

• It is elastin that gives young skin its firmness, smoothness, and resiliency. It is elastin that gives young skin its firmness, smoothness, and resiliency.

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Recognized Causes of Skin AgingRecognized Causes of Skin Aging

• Mechanical aging Mechanical aging

• Extrinsic agingExtrinsic aging

• Intrinsic AgingIntrinsic AgingOld SkinOld Skin Young SkinYoung Skin

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Medical Text BookMedical Text Book

School of Medicine at University of PennsylvaniaSchool of Medicine at University of PennsylvaniaB’Nai Brith Americanism AwardB’Nai Brith Americanism AwardMaison De Navarre Gold Medal AwardMaison De Navarre Gold Medal AwardAmerican Academy of Dermatology memberAmerican Academy of Dermatology member

•Authored >60 scientific papersAuthored >60 scientific papers•Given >100 scientific mtg. presentationsGiven >100 scientific mtg. presentations•Contributed >10 chapters to scientific textsContributed >10 chapters to scientific texts•Published 4 booksPublished 4 books

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Peter T. Pugliese, M.D.Peter T. Pugliese, M.D.

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Physiology of SPhysiology of Skin Sagging and Wrinkles kin Sagging and Wrinkles

• The wrinkle starts in the dermis as a decrease in the quantity and quality of elastin production by fibroblast The wrinkle starts in the dermis as a decrease in the quantity and quality of elastin production by fibroblast

• Cells which decrease in fiber causes the skin elastin fibers to lose their snap, and thus the skin becomes lax and loose. The skin sags. Cells which decrease in fiber causes the skin elastin fibers to lose their snap, and thus the skin becomes lax and loose. The skin sags.

• The skin is no longer able to retract to its original “young firm” state. As a result, sagging and crinkling occur in a pattern that is called The skin is no longer able to retract to its original “young firm” state. As a result, sagging and crinkling occur in a pattern that is called wrinkles. wrinkles.

• Ethocyn increases important skin elastin fiber quantity and quality to that of young, 20 year old skin elastin quantity and quality. This Ethocyn increases important skin elastin fiber quantity and quality to that of young, 20 year old skin elastin quantity and quality. This has been proven (p<0.001) in controlled, punch biopsy Ethocyn clinical trials at major university medical centers. has been proven (p<0.001) in controlled, punch biopsy Ethocyn clinical trials at major university medical centers.

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The Single Most Important Cause…. The Single Most Important Cause….

Peter T. Pugliese M.D.Peter T. Pugliese M.D.Internationally acclaimed author of the Internationally acclaimed author of the dermatology textbooks:dermatology textbooks:Physiology of Skin IIPhysiology of Skin II and and Advanced Professional Skin Care Advanced Professional Skin Care

““The single most important cause of age related wrinkles is the The single most important cause of age related wrinkles is the loss of skin elastin fibers, Everyone, whether female or male loss of skin elastin fibers, Everyone, whether female or male will begin to lose skin elastin fibers at age 25. will begin to lose skin elastin fibers at age 25. Elastin fibers are the restorative force on the skin.”Elastin fibers are the restorative force on the skin.”

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Only One Product in the World Can….

““Only one product in the world can restore your elastin level to Only one product in the world can restore your elastin level to that of 20 year old skin: Ethocyn.”that of 20 year old skin: Ethocyn.”

Peter T. Pugliese M.D.Peter T. Pugliese M.D.Internationally acclaimed author of the Internationally acclaimed author of the dermatology textbooks:dermatology textbooks:Physiology of Skin IIPhysiology of Skin II and and Advanced Professional Skin Care Advanced Professional Skin Care

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Important Elastin Fibers and Skin AgingImportant Elastin Fibers and Skin Aging

• Elastin levels decrease

• Skin loses contour and firmness

• Skin sags

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Ethocyn and Its Mechanism of Action

Blocks what causes fibroblasts skin Blocks what causes fibroblasts skin cells to stop producing elastin–the cells to stop producing elastin–the important youth-rendering skin’s important youth-rendering skin’s rubber bands–that we have when rubber bands–that we have when we are young. we are young.

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Intrinsic Aging and Loss of Skin Elastin Fibers

• Both men and women are born with DHT receptors in their fibroblast cells

• We are genetically predisposed to inheriting the amount, or quantity, of DHT receptors that we possess

• After 25-35 years of age, no matter what our genetic make-up, we will have more DHT receptors than anti-androgens. We need to use topical Ethocyn 2x per day

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An Androgen Enters the Skin Fibroblast cellAn Androgen Enters the Skin Fibroblast cell• Testosterone in males and AndrosteindioneTestosterone in males and Androsteindione• in females are converted to DHT intracellularlyin females are converted to DHT intracellularly

• DHT inside the skin cells binds to the DHT receptorDHT inside the skin cells binds to the DHT receptor

• Bound DHT-DHT receptor complex translocates to Bound DHT-DHT receptor complex translocates to the nucleusthe nucleus

• When bound complex hits the nucleus, this signals When bound complex hits the nucleus, this signals the nucleus to stop producing elastinthe nucleus to stop producing elastin

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Ethocyn Topical Application and Proven Penetration

The Ethocyn molecule penetrates skin dermis:• Organically synthesized, non-steroidal antiandrogen

• Has a molecular weight of 266

• Penetrates through the stratum corneum to the dermis and enters the skin fibroblast cells which are the manufacturing sites for elastin production

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• Circulating Testosterone (T) in males and Androsteindione (A) in females passively defuses into fibroblast cells

• T and A converted to DHT via 5 alpha reductase enzyme

• DHT binds to the DHT receptor

• Bound complex translocates to the nucleus When bound complex hits nuclear membrane: signals nucleus to decrease/ stop producing elastin protein• Ethocyn has an affinity for the DHT receptorEthocyn has an affinity for the DHT receptor• Competitvely blocks the DHT from binding to its Competitvely blocks the DHT from binding to its receptorreceptor• Allows for more elastin to be producedAllows for more elastin to be produced

DHT Receptor-DHT Androgen’ Fibroblast Cell Physiology:

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Ethocyn Clinical Trials Deliver at p<0.001Ethocyn Clinical Trials Deliver at p<0.001

What can one expect to experience and see using Ethocyn?•U.C.L.A. •University of Shanghai •Dermatologist Trials Worldwide•Plastic Surgeon Trials alone; andin combination with Fraxel Laser

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Research and PublicationsResearch and Publications

• Over $20 million and 19 years have been expended on Ethocyn research and development to date.

• Ethocyn is a unique, patented, clear and odorless oil concentrate invented by biochemist Chantal Burnison.

• Research aided by advanced cell-receptor laboratories, radioisotopes, and computer software.

Ethocyn research and production laboratoryEthocyn research and production laboratory

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Page 26: Tru Face Essence Ultra Ethocyn Tel-Aviv, Israel November, 9 th 2011 Tru Face essence ULTRA

Ethocyn A clinically proven, topical, efficacious target tissue,

non-steroidal ingredient.p<0.001

Ethocyn Clinical EfficacyEthocyn Clinical Efficacy

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U.C.L.A. and Other University Ethocyn Clinical Trials

• Very objective Clinical Trials’ endpoints; evaluation objective (p<0.001)Very objective Clinical Trials’ endpoints; evaluation objective (p<0.001)

• Precise quantitative assessment of skin elastin fiber content of subjects before and Precise quantitative assessment of skin elastin fiber content of subjects before and after the topical use of Ethocynafter the topical use of Ethocyn

• Clinical Protocols were reviewed and approved by the United States FDAClinical Protocols were reviewed and approved by the United States FDA

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UCLA Dept. of Dermatology Clinical TrialsUCLA Dept. of Dermatology Clinical Trials

Clinical Trials• Conducted by Dr. Richard Strick, M.D. Clinical Professor of Dermatology at U.C.L.A.

•Protocols reviewed and approved by USA FDA

• Presented Ethocyn Clinical Trials’ research at the American Academy of Dermatology Medical Conference and several other medical forums.

Dr. Richard Strick, M.D.Dr. Richard Strick, M.D.

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• 2mm Punch biopsies --actual skin -- were taken from each subject ; slides randomized-thereby hiding identity of Subjects and time sequence.

• Quantitative computer image analysis of biopsies were conducted at Baseline, 1,2,3,4 and 6 months to assure accuracy and statistically significant results (p<0.001)

• Biopsy analyses: 250+ patients, male and female; 25-77 yrs of age; different ethnicities.

Ethocyn Clinical Efficacy University Medical Center’s Phase II Ethocyn Clinical

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Detailed Protocol5 micron Verhoff-Van Giesen (VVG) stained sections for formalin fixed, paraffin embedded full depth skin punch biopsies were analyzed by standardized, semi-automated image analysis to determine elastin content ratios.A trained technician, familiar with skin tissue morphology, used a software-assisted drawing tool to define a sampling area of the dermal layer a constant distance away from the epidermal layer and containing as much of the dermal layer of the skin visible with a 4X objective. The size of this sampling area, in square microns was recorded by the system.Elastin fiber content was measured within the sampling area using a 20X objective. Elastin fibers stain black with the VVG stain. Standardized image analysis was used to detect all black fibers within the sampling area. Automatic size filters excluded stained areas which were either too large or too small to be elastin fibers. Additional image analysis filters ensured that no fiber was measured more than once, even if measurements were made in adjacent, overlapping fields of view. Finally, technicians were able to manually exclude staining that was determined by observation not to be specific for elastin.All biopsies were measured twice independently by two different technicians. When possible, three serial sections were cut from each biopsy and the best quality section was analyzed. Biopsies for which sections were of poor quality or below a reasonable minimum size were excluded. Biopsies for which the data collected by both technicians did not agree within 10%, were also excluded.Data including sampling area, elastin area, and elastin to sampling area ratio were exported to Excel for subsequent analysis. Comparisons were made via students t-test with an alpha of 0.05.Pictures are attached. The include:Two consecutive sections from the same biopsy imaged with a 4X objective.Screenshot of the BIOQUANT software inspecting a biopsy section. Screen shot shows raw sampling area and elastin data, the boundary and elastin measurements on the section.A sample paraffin block containing a biopsy.The leica microtome used to cut sections from the paraffin block.An street corner photograph of the research office block where we have our lab operations. It's not much to look it. It's one lab in a very large building of labs.A photograph of a typical BIOQUANT workstation. A skin biopsy is displayed on the screen of the workstation.The imaging system used to collect images of the sections. This is an inverted automated scanning microscope. The blue and white box with the joystick is the movement controller. The black and white tube sticking out the right above the joystick is the digital camera.The last image is the imaging tray. It allows us to orient the section so that the epidermis is always up, regardless of how the section may be mounted on the slide.Biography of BIOQUANTBIOQUANT Image Analysis Corporation was founded in 2001 to develop analytical systems and services for lifescience research. BIOQUANT systems collect the data to quantitative describe the tissues of every organ in the body from the skin to the retina to bone.Research services provided by BIOQUANT allow sponsoring companies to access the analytical capacities of BIOQUANT's systems without the need to establish their own research facilities. Through a consultative process which may include experts from BIOQUANT's large network of partnering scientists, clients are assured of comprehensive and rigorous research services.BIOQUANT is on the cutting edge of digital pathology services, having recently introduced a modularized, yet fully automated microscopy imaging platform. This platform retains the flexibility of a traditional microscopy system that is needed to adapt to novel research projects while enabling high-throughput sub-micron slide scanning. This gives sponsoring organizations access to all of their data from any internet connected computer.

Nathanael Reveal, President

Bioquant: Ethocyn Verhoeff Stained Clinical Biopsy Analyses

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Bioquant Image Analysis Corporation Photos Nashville, TN

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Double blind, punch biopsies conducted on hundreds of Subjects (25-77 years of age) at Double blind, punch biopsies conducted on hundreds of Subjects (25-77 years of age) at independent university medical centers confirm (p <0.001) Ethocyn increases your skin’s independent university medical centers confirm (p <0.001) Ethocyn increases your skin’s important elastin fiber content to the youthful levels of 20 year old individuals. Study’ important elastin fiber content to the youthful levels of 20 year old individuals. Study’ Control Group 18-25 year olds.Control Group 18-25 year olds.

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Synopsis and Conclusion: For all Subjects in all Ethocyn Clinical Trial Studies: All laboratory results both in Baseline and Final Visit were normal.

During the analysis of the lab records, no significant change between Before Treatment and After Treatment was found. This was in line with the Ethocyn C14 Clinical Trial that confirmed its 100% metabolism in the skin by beta oxidation such

that there is no parent Ethocyn compound entering systemic circulation.

Hematology:

White Blood Cells

Hemoglobin

Blood Platelet Count

Red Blood Cells

Urinalysis:

White Blood Cells

Red Blood Cells

Protein

Others

Serum Chemistry: SGPTSGOT Total Protein Cholestrol CreatininePotassiumSodium BUN Alkaline Phosphatase TrigluderidesTotal Bilirubin

 Hormone Assay:Total and Free Testosterone (TT and FT)Leutinizing Stimulating Hormone (LH)Follicle Stimulating Hormone (FSH)Estradiol.

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Ethocyn Clinical Trials’ Safety Evaluations

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A Topical, Safe, and Efficacious Cosmetic Ingredient

100% conversion via β oxidation in dermis to non-AA

Non-AA 1ºmetabolite8 - 10 hours

CONCLUSION: non-parent AA Ethocyn molecule never enters systemic circulation. Confirmed viapharmacokinetic profiles in 3 species including human C14 studies (Groningen, Holland)

O OOO

OCH2H3 OHOCH3

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U.C.L.A. Ethocyn Clinical Trial ResultsU.C.L.A. Ethocyn Clinical Trial Results

•FDA protocols: Safety and Efficacy end-points FDA protocols: Safety and Efficacy end-points

•Subjects: 40-77 years of age; Males and FemalesSubjects: 40-77 years of age; Males and Females

•6 month; 3 month Studies6 month; 3 month Studies

•Baseline elastin: 9.2% (mean) in Six Month Study;Baseline elastin: 9.2% (mean) in Six Month Study;• 8.1% (mean) in Three Month Study8.1% (mean) in Three Month Study

•End elastin: 18.2% (mean) in Six Month UCLA Study; End elastin: 18.2% (mean) in Six Month UCLA Study; •21.3% (mean) in Three Month UCLA Study 21.3% (mean) in Three Month UCLA Study

• UCLA Control Group (18-25 years old) elastin: 15.6%UCLA Control Group (18-25 years old) elastin: 15.6%

•P<0.001P<0.001

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Ethocyn Clinical Trials’ Efficacy Results

Percent Increase In Elastin Content

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Breaking the Code at U.C.L.A. Ethocyn Clinical TrialsBreaking the Code at U.C.L.A. Ethocyn Clinical Trials

EthocynEthocyn

Topical BID application of Ethocyn™ by patients aged 40-77 years of age restores elastin Topical BID application of Ethocyn™ by patients aged 40-77 years of age restores elastin production to levels normally obtained in youth (ages 18-25). The mean level of elastic production to levels normally obtained in youth (ages 18-25). The mean level of elastic tissue in Ethocyn™ treated individuals increased by 100% (in some patients over 500%) tissue in Ethocyn™ treated individuals increased by 100% (in some patients over 500%) (P<0.001). Every individual, male and female subject, had shown improvement and had (P<0.001). Every individual, male and female subject, had shown improvement and had smoother, tighter and less wrinkled skin.smoother, tighter and less wrinkled skin.

American Academy of Dermatology Medical Conference, San Francisco, CaliforniaAmerican Academy of Dermatology Medical Conference, San Francisco, CaliforniaRichard Strick, M.D.Richard Strick, M.D.Diplomat of American Academy of DermatologyDiplomat of American Academy of DermatologyClinical Professor of Dermatology, U.C.L.A. School of MedicineClinical Professor of Dermatology, U.C.L.A. School of Medicine

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Ethocyn Clinical Trials and Plastic Surgery

Jeffrey D. Hoefflin, M.D., F.A.C.S, F.I.C.S.

• Fully trained General surgeon, plastic surgeon• Dual Board Certified Surgeon• Diplomate, The American Board of Plastic Surgery• Fellow, The American College of Surgeons• Fellow, The International College of Surgeons• Fellow, Bay Surgical Society• Member, Los Angeles Society of Plastic Surgeons

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• Next generation of ‘safe’ and efficient’ lasers

• Less downtime compared to traditional lasers

• Can be performed in office setting

• Five to seven day healing process

• Indications: pigment dyschromias, hyperpigmentation,

•melasma, all levels of rhytids.

Fractionated Laser Resurfacing

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• 2009 Ethocyn and Laser Resurfacing Study

• Fraxel Fractionated CO2 – Full Face Laser Skin Resurfacing

• Topical BID application of Ethocyn®

• Patient age range (aged 28-62 years) Mean elastic tissue level in treated individuals increased 100% (p<0.001).

• Every individual (male and female) showed improvement and had smoother, tighter and less wrinkled skin.

Laser Resurfacing Study Protocols Dr. Jeffrey Hoefflin M.D., F.A.C.S., FICS

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Dr. Hoefflin Ethocyn + Laser Study • 8 weeks Clinical Trials’ Study; 20 Patients: Aged 28-62 yrs.• Ethocyn application BID on one side and placebo on other.

Double Blind, Placebo Controlled• Laser Procedure after 45 days of Ethocyn BID (2x per day)

regimen• Interrupt Ethocyn application 5 days (post surgically)• Resume Ethocyn application• Physician and patients subject to analysis• Conclusion, Patients Using Ethocyn Remarked More Younger,

Firmer Skin on Ethocyn Treated Side

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Ethocyn and Laser Resurfacing Patient Example

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Ethocyn and Laser Resurfacing Patient Example

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Ethocyn and Laser Resurfacing Patient Example

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• Topical BID application of Ethocyn®

• Patients (aged 28-62 years) – elastin restored to youth levels (ages 18-25)

• Mean elastic tissue level in treated individuals increased 100% (p<0.001).

• Every individual (male and female) showed improvement and had smoother, tighter and less wrinkled skin.

Ethocyn Optimizes Laser Results

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• 2mm Punch biopsies --actual skin-- were taken from each subject

• Quantitative computer image analysis of biopsies were conducted to assure accuracy and statistically significant results (p<0.001)

Dr. Hoefflin Ethocyn + Laser Clinical Trial 2010

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Ethocyn Medical Conferences and Publications 2011-2012

Qara Raymi Dermatology Conference, Lima, PeruAugust 26-29, 2011

American Society of Plastic & Reconstructive Surgery:Oct 2011 - Volume 128 - Issue 4S - p 110doi: 10.1097/01.prs.0000406341.77839.a2American Society of Plastic Surgery- Poster; Sept 23-27, 2011 in Denver, Colorado.

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Advantages of Topical Ethocyn Tru Face Essence Ultra• All serums formulated at clinically efficacious dose( Dose Response Studies: 15%, 10%, 5%, 0.5%, 0.25%, 0.0025%)

• Non-phototoxic

• Hypoallergenic

• Non-irritating

• Non-fragrance

• Proprietary anti-inflammatory, collagen boosting ingredient formulation, with excellent mmp inhibitor ingredients

• Multi-functional formulation simplifies your daily skin care regimen

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Ethocyn Tru Face Essence Ultra Formulated with Superior Collagen Boosting & Elastin and Collagen Preservation

Ingredients

49Jeffrey D. Hoefflin, M.D., F.A.C.S. - ETHOCYN

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Ethocyn Tru Face Essence Ultra Formulated with Superior Antioxidants

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How to Use Ethocyn and Tru Face Essence How to Use Ethocyn and Tru Face Essence Ultra Ultra

Ethocyn Application: • Metabolizes in the body within 8 to 10 hours–therefore it should be applied TWICE DAILY, morning and evening.

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Ethocyn and Sun Exposure

• Non-Phototoxic – You CAN go in the sun without worrying about redness or swelling.

• Try to protect your skin from the sun because the sun causes elastin fibers in the skin to become hard and non-resilient; a condition known as elastosis.

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Ethocyn

Increases your skin’s ‘Rubber Bands’ (elastin fibers) to that of 20 year old skin with Ethocyn containing Tru Face Essence Ultra serum for…Firmer…. Smoother… More Snap Back, Beautiful Skin

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Ethocyn Announements

“A major breakthrough in the fight against skin aging.”-Dr. Bruce Hensel, Channel 4 News

Ethocyn’s importance previewed on USA television news stations when Dr. Richard Strick presented at AAD Medical Conference“Ethocyn gives skin the elastin fiber content of 20 year old skin.”

–Dr. Richard Strick UCLA Dermatology Professor

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Numerous Television News BroadcastsCovering Ethocyn clinical trials’ medical conference publications

““The Fountain of Youth in a bottle” The Fountain of Youth in a bottle”

-Hard Copy Investigative News Report-Hard Copy Investigative News Report

““Studies show this product works Studies show this product works differently fromdifferently from

others, and experts say it does work” others, and experts say it does work”

-NBC (Channel 4) Television News Report-NBC (Channel 4) Television News Report

““What’s in this little bottle couldWhat’s in this little bottle couldturn back the hands of time”turn back the hands of time”

-KTLA (Channel 5) Television News Report-KTLA (Channel 5) Television News Report

““The compound actuallyThe compound actually restores elasticity to aging skin.”restores elasticity to aging skin.”

-KTLA (Channel 5) Television News Report-KTLA (Channel 5) Television News Report

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Page 56: Tru Face Essence Ultra Ethocyn Tel-Aviv, Israel November, 9 th 2011 Tru Face essence ULTRA

Medical Directors of U.S. University Dermatology Departments state:“Ethocyn is the most effective cosmetic product available.”

Interview of Dr. Tina Alster, Clinical Professor of Dermatology at Georgetown University School of Medicine.Her patients include politicians, newscasters, models and lawyers.Dr. Alster said, “To treat and prevent my own eye skin-area wrinkles: I use a drop of Chantal Ethocyn Vial Serum every morning and evening around my eyes…I recommend Ethocyn to all my patients.”

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Ethocyn Users’ Testimonials

““I feel like ethocyn is actually repairing I feel like ethocyn is actually repairing my skin.”my skin.”““It’s the perfect little magic drop.” It’s the perfect little magic drop.”

““I feel younger, I feel like I look I feel younger, I feel like I look younger.” younger.” ““The ethocyn essence vial’s are The ethocyn essence vial’s are

Easy to use and gave me great results.” Easy to use and gave me great results.”

““Within two weeks I saw a big difference.”Within two weeks I saw a big difference.”““The ethocyn changed my skin in a wayThe ethocyn changed my skin in a way I’ve never seen before.” I’ve never seen before.”

““The tightness in my skin came back, The tightness in my skin came back, I think everybody should know about I think everybody should know about Ethocyn.” Ethocyn.”

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Page 58: Tru Face Essence Ultra Ethocyn Tel-Aviv, Israel November, 9 th 2011 Tru Face essence ULTRA

Ethocyn Users’ TestimonialsEthocyn Users’ Testimonials

““It really just feels good” It really just feels good”

““The lines have disappeared, I’m not feeling The lines have disappeared, I’m not feeling uncomfortable any more.” uncomfortable any more.”

““Next to being a baby, this is the bestNext to being a baby, this is the best my skin has ever looked.” my skin has ever looked.”

““My lines have disappeared, the sagginess My lines have disappeared, the sagginess has lifted.” has lifted.”

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Ethocyn Treatment ProductsUsed everyday by men and women who care about skin health and beauty

Karen Philips, a working American wife, decided to test Ethocyn herself by using the product on only half of her face, twice a day, for 120 days. The results of her “half face test” are seen in this picture.

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THE FUTURE IS NOW

Tru Face™

essence ULTRA

Everyday. Twice a day.Everyday. Twice a day.

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