the synthetic bone company angstrom medica, inc. 150-a new boston street woburn, ma 01801...
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The Synthetic Bone Company™
Angstrom Medica, Inc. 150-A New Boston Street Woburn, MA 01801 781.933.6121 www.angstrommedica.com
Utilizing Nanotechnology
to
Develop Medical Devices
Edward S. Ahn, Ph.D.
Angstrom Medica, Inc. - Proprietary and Confidential
Why Nanotechnology?
All interactions occur at an interface
Maximize interactions by maximizing interface
Increase surface area to volume ratio
Unique size dependent properties
Angstrom Medica, Inc. - Proprietary and Confidential
Nanotechnology and the Medical Device
PhysicianInput
ProductDefinition
RegulatoryApproval
Manufacturing Sales
Does nanotechnologysolve a compelling
clinical need?
510(k) or PMA?
Can you make it?
FINANCING
Do the potential rewards out weigh risks?
Angstrom Medica, Inc. - Proprietary and Confidential
Defining The Product
Compelling Clinical Need What kind of product?
Incremental product improvementRevolutionary procedure
IssuesTechnology looking for a homeHow do clinicians contextualize nanotechnology?Are there more conventional alternatives?
Angstrom Medica, Inc. - Proprietary and Confidential
Angstrom’s ProductsSpinal Fusion Devices Angstromplasty
Hip Fracture Prevention
100 nm100 nm
Bone Screws
Angstrom Medica, Inc. - Proprietary and Confidential
FDA Approval
Same but different strategy First nanomedical device approved by FDA
Nanocrystalline CaP bone void filler
Incremental product improvement Should be 510(k)
Bone screws and spinal fusion devices
Revolutionary Procedure May require clinical trials
Angstromplasty
Angstrom Medica, Inc. - Proprietary and Confidential
Manufacturing
Nanotechnology = Expensive? InfrastructureSpecialized talentMulti-step processingLimited outsourcingReproducibility and Reliability
Nanotechnology is stochastic
Angstrom Medica, Inc. - Proprietary and Confidential
Angstrom’s Manufacturing Process
100 nm
Precipitation Forging Machining
Angstrom Medica, Inc. - Proprietary and Confidential
Financing
Grants Angel Investors Strategic Partners Institutional Investors
Technical Risk Marketing Risk Execution Risk
engineering small miracles™
Angstrom Medica, Inc. 150-A New Boston Street Woburn, MA 01801 781.933.6121 www.angstrommedica.com