LuteovirusLuteoviridae

Leslie L. Domier

. Barley yellow dwarf virus PAV. Fig. 1

Negatively stained virion. Length of bar (nm): 25

Virion

Morphology: Icosahedral

C#

Envelope:

. Tidona, G. Darai (eds.), The Springer Index of Viruses, DOI 10.1007/978-0-387-95

Springer Science+Business Media, LLC 2011

No

Diameter (nm):

25–30

Length (nm):

–

Structural components:

Capsid

Buoyant density (g/mL):

1.39–1.40

Buoyant density method:

CsCl

Lipid composition:

None

Additional information:

919-1,

822 Luteovirus

Genome

Nucleic acid: RNA

Strandedness:

Single-stranded

Polarity:

Positive-sense

Configuration:

Linear

Segment organization:

Segment no. 1 (kb): 5.3–6.0

One segment(s):

5.3–6 (kb) total (calculated)

47.8–48.5

G + C content (%):

mRNA transcripts:

2–3

Open reading frames:

5–8

Additional information:

Luteoviruses produce 2–3 subgenomic RNAs. The largest, subgenomic RNA1, expresses the coat (P3),

movement (P4) and aphid transmission (P3-P5) proteins

Replication

Entry mechanism: Aphid feeding

Site of transcription:

Cytoplasm

Transcriptase:

Virus-encoded RNA-dependent RNA polymerase

Site of genome replication:

Unknown

Replicase:

Virus-encoded RNA-dependent RNA polymerase

Replication intermediate:

Negative sense genomic RNA

Site of virion assembly:

Cytoplasm

Egress mechanism:

Aphid feeding

Additional information:

History

Year of

event

1951

Event

Description of Barley yellow dwarf virus disease in California

References

Oswald JW, Houston BR (1951) Plant Dis Rep

11:471–475

Esau K (1957) Am J Botany 44:245–251

1957 Description of phloem tissue specificity of Barley yellow dwarf

virus

Identification of Yd2 gene for resistance to Barley yellow dwarf

1959

virus in barley

Purification of Barley yellow dwarf virions and correlation with

Rasmusson DC, Shaller CW (1959) Agron J

51:661–664

Rochow WF, Brakke MK (1964) Virology

1964

infectivity

Determination of specificity of transmission of Barley yellow

24:310–322

Rochow WF (1969) Phytopathol 59:1580–1589

1969

dwarf virus strains by aphids

Description of Soybean dwarf disease in Japan

1969 Tamada T, Goto K, Chiba I, Suwa T (1969) Ann

Phytopathol Soc Jap 35:282–285

Luteovirus 823

Year of

event

1979

Event

Use of enzyme-linked immunosorbent assay for detection and

References

Lister RM, Rochow WF (1979) Phytopathol

diagnosis of Barley yellow dwarf virus

Elucidation of role of aphid accesory salivary gland in

69:649–654

Gildow FE, RochowWF (1980) Virology 104:97–108

1980

transmission specificity

Production of monoclonal antibodies to Barley yellow dwarf

1984

virus

Determination of sequence and genomic organization of Barley

Hsu HT et al (1984) Phytopathol 74:600–605

1988

yellow dwarf virus

Determination of the sequence and genomic organization of

Miller WA et al (1988) Nucl Acids Res 16:6097–6111

1994

Soybean dwarf virus

Use of coat-protein mediated resistance to Barley yellow dwarf

Rathjen JP et al (1994) Virology 198:671–679

1997

virus

Revision of taxonomy of Barley yellow dwarf virus and other

McGrath PF et al (1997) Europ J Plant Path

103:695–710

D’Arcy CJ et al (2000) VIIth Report of the ICTV

2000

Luteoviridae members

Identification of four distinct strains of Soybean dwarf virus and

2001

thier principle aphid vectors

Bean leafroll virus shown to be a member of the Luteovirus

Terauchi H et al (2001) Arch Virol 146:1885–1898

2002

genus

Elucidation of long-distance RNA-RNA interactions in luteovirus

Domier LL et al (2002) J Gen Virol 83:1791–1798

2006

gene expression and replication

Biolistic inoculation of soybean plants with soybean dwarf virus

Miller WA, White KA (2006) Ann Rev Phytopathol

44:447–467

Yamagishi N et al (2006) J Virol Meth 137:164–167

2006

2008

Identification of Rose spring dwarf associated virus as a member Salem NM et al (2008) Virology 375:354–360

of the luteovirus genus

Soybean dwarf virus-resistant transgenic soybeans with the

2007

sense coat protein gene

TougouM et al (2007) Plant Cell Rep 26:1967–1975

Genus Members

Wild-type

Species name

Barley yellow dwarf virus PAV

Synonyms

Oat red leaf virus

strains/

isolates

Aus, IL,

Natural host

range

Monocot

Experimental

host range

Membership

status

Type species

(BYDV-PAV)

Barley yellow dwarf virus MAV

NY, P

NY, PS1

plants

Monocot

(BYDV-MAV)

Barley yellow dwarf virus PAS

plants

Monocot

Approved member

(BYDV-PAS)

Barley yellow dwarf

virus PAV-129

(BYDV-PAV-129)

Legume yellows virus

plants

Approved member

Bean leafroll virus (BLRV)

(LYV); Michigan alfalfa

virus; Pea leafroll virus

(PeLRV)

Dicot plants

Approved member

Rose spring dwarf associated

virus (RSDaV)

Dicot plants

Approved member

.N

824 Luteovirus

Wild-type

Species name

Soybean dwarf virus (SbDV)

Genome organization and expr

umbered arrows represent open

Synonyms

Subterranean clover

ession of Barley yellow

reading frames

strains/

isolates

DP, DS,

dwarf virus-

Natural host

range

Dicot plants

PAV. Fig. 2

Experimental

host range

Membership

status

Approved member

red leaf virus (SCRLV)

YP, YS

Barley yellow dwarf virus-GAV

(BYDV-GAV)

Monocot

plants

Tentative member

Nucleotide Sequences

Access

Genomic region

Complete genome

Species

BYDV-PAV

Strain

Aus

Nucleotides

5,677

number

NC_004750

References

Miller WA et al (1988) Nucl Acid Res 16:6097–6111

Complete genome

BYDV-MAV PS1 5,273 NC_003680 Ueng PP et al (1992) J Gen Virol 73:487–492

Complete genome

BYDV-PAS PAV-129 5,695 NC_002160

Complete genome

BYDV-GAV 5,685 NC_004666

Complete genome

BLRV Michigan 5,964 NC_003369 Domier LL et al (2002) J Gen Virol 83:1791–1798

Complete genome

RSDaV California 5,808 NC_010806 Salem NM et al (2008) Virology 375:354–360

Complete genome

SbDV YS 5,853 NC_003056 Terauchi H et al (2001) Arch Virol 146:1885–1898

Proteins

Protein name Number of Molecular Time of Additional

Protein name

RNA-dependent

abbreviation

P1

amino acids

339–374

weight (kDa)

38.4–43.4

expression

Early

Accession numbers

NP_840067.1;

information

RNA polymerase P1

NP_620065.1;

NP_037636.1;

NP_813790.1;

NP_563610.1;

YP_001949737.1;

NP_150430.1

Luteovirus 825

Protein name Number of Molecular Time of Additional

Protein name

RNA-dependent

abbreviation

P1-P2

amino acids

867–901

weight (kDa)

98.6–103.4

expression

Early

Accession numbers

NP_840014.2;

information

Product derived

RNA polymerase

P1-P2 fusion

NP_620064.1;

NP_037635.1;

NP_813789.1;

NP_563609.1;

YP_001949736.1;

NP_150431.2

NP_840015.1;

from -1 ribosomal

frameshift from

ORF1 into ORF2

Capsid protein P3

CP 199–220 21.7–24.4 Late

NP_620067.1;

NP_037638.1;

NP_813792.1;

NP_563612.1;

YP_001949739.1;

NP_150432.1

NP_840016.1;

Movement

protein P4

P4

142–186 17.0–20.8 Late

NP_620068.1;

NP_037639.1;

NP_813793.1;

NP_563613.1;

YP_001949740.1;

NP_150433.1

NP_840017.2;

ORF4 is translated

via leaky scanning

on subgenomic

RNA1

Aphid transmission

readthrough

protein P5

RTP

649–721 71.3–80.8 Late

NP_620066.1;

NP_037637.1;

NP_813791.1;

NP_563611.1;

YP_001949738.1;

NP_150434.2

NP_840018.1;

Translated from

subgenomic RNA1

as a fusion protein

via read-through of

ORF3 stop codon

P6

P6 41–63 4.0–6.6 Unknown

NP_620069.1;

NP_037640.1;

NP_813794.1;

YP_001949741.1

NP_840019.1;

Highly variable

protein

P7

P7 32–55 3.4–6.0 Unknown

YP_001949742.1

Reported only in

BYDV-PAV and

RSDaV

Reported only in

P8 P8 40 4.2 Unknown YP_001949743.1

RSDaV

Biology

Permissive Tissue

Species

BYDV-PAV

cell lines

Monocot

tropism

Phloem

Cytopathic effects

Filaments, vesicles,

Additional information

Protoplasts were inoculated with full-length in vitro

protoplasts

Dicot

nuclear distortion

transcripts of BYDV-PAV genomic RNA

Protoplasts were inoculated with full-length in vitro

SbDV

protoplasts

Phloem

transcripts of SbDV genomic RNA

826 Luteovirus

Diseases

Causative Affected Transmission Geographic

Disease

Barley yellow dwarf

agent

BYDVs

organisms

Monocot

Disease characteristics

Stunting, yellow-, orange-, red-,

route/vector

Aphids

Treatment

distribution

World-wide

plants

Dicot plants

purple-leaf discoloration

Rolling of leaves stunting

(circulative)

Aphids

Bean leafroll BLRV

(circulative)

Aphids

World-wide

Soybean dwarf

SbDV Dicot plants Stunting, leaf yellowing

(circulative)

Aphids

World-wide

Rose spring dwarf

RSDaV Dicot plants Dwarfing, rosetting of new

growth, bud break, vein clearing

(circulative)

World-wide

Diagnosis

Sample Detection

Method

Enzyme-linked

Species

BYDV-PAV

material

Plant sap

target

Viral antigens

References

D’Acy CJ et al (1992) Plant Dis 76:273–276

immunosorbent assay

Dot-blot

hybridization

PCR amplification of

BYDV-PAV

Plant sap Viral RNA Liu Y et al (2007) J Virol Meth 145:22–29

conserved major

capsid protein coding

region

PCR amplification of

BYDV-MAV

Plant sap Viral RNA Malmstrom CM, Shu R (2004) J Virol Meth 120:69–78

conserved major

capsid protein coding

region

Enzyme-linked

SbDV

Plant sap Viral RNA Harrison B et al (2005) Plant Dis 89:28–32

immunosorbent assay

SbDV

Plant sap Viral antigens Hewings AD, Damsteegt VD (1986) Phytopathol

76:1075–1075

References

D’Arcy CJ, Burnett PA (eds) (1995) Barley yellow dwarf: 40 years of

progress. APS Press, St Paul

Gray S, Gildow FE (2003) Annu Rev Phytopathol 41:539–566

Miller WA, Rasochova L (1997) Annu Rev Phytopathol 35:167–190

Miller WA, White KA (2006) Annu Rev Phytopathol 44:447–467

Miller WA, Liu SJ, Beckett R (2002) Mol Plant Pathol 3:177–183

Peiffer ML, Gildow FE, Gray SM (1997) J Gen Virol 78:495–503