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The Role of Philanthropy in Funding Research

Carolyn AldigéCarolyn Aldigé

President and FounderPresident and Founder Prevent Cancer FoundationPrevent Cancer Foundation

February 9, 2008February 9, 2008

Our Mission

The mission of the Prevent Cancer Foundation is cancer prevention and early detection through research, education and community outreach to all populations, including children and the underserved.

Our Focus

Cancers that can be prevented through lifestyle changes or detection and treatment in the early stages.

Breast Cervical Colorectal Lung Oral Prostate Skin Testicular

Accomplishments

Since 1985, we have provided more than $97 million in support of cancer prevention research, education and outreach programs nationwide.

We’ve played a pivotal role in developing a body of knowledge that is the basis for important prevention and early detection strategies.

Federal Funding for Medical Research

National Institutes of Health (NIH) is the largest provider of outside funding for grants in training, research, fellowships, construction and laboratories.

The NIH invests over $29.5 billion annually in medical research.

More than 80% of the NIH’s funding is awarded through almost 50,000 competitive grants to more than 325,000 researchers at over 3,000 universities, medical schools, and other research institutions in every state and around the world.

Federal Funding for Medical Research

NIH funding levels to remain flat again in 2008 (the FY 2008 domestic spending bill includes $29.5 billion for the NIH) – a less than 1 percent increase. (Congress asked for a 3.6 percent increase.)

NIH funding continues to fail to keep pace with the 3.7 percent biomedical inflation rate.

AAMC says lack of NIH funding growth threatens the momentum of medical research progress.

Industry Funding for Medical Research

R&D investments made by research-based pharmaceutical companies.

Total investments in biotechnology and pharmaceutical R&D by America's research-based companies reached $51 billion in 2005.

Leads the world in investing in the search for new cures and treatments.

Regarded as the most research-intensive industry in America.

Philanthropic Funding - Other Foundations

The Robert Wood Johnson Foundation is the nation's largest philanthropy devoted exclusively to improving the health and health care of all Americans.

In 2006, it awarded approximately $400 million in grants in: Building human capital Childhood obesity Health insurance coverage Public health Quality/equality Vulnerable populations

Philanthropic Funding - Other Foundations

Howard Hughes Medical Institute is a recognized leader in biomedical research.

300 HHMI investigators direct Institute research laboratories on the campuses of universities and other research organizations throughout the United States.

By appointing scientists as Hughes Investigators — rather than awarding research grants — HHMI is guided by the principle of "people, not projects."

The Institute solicits nominations from these institutions, with the aim of identifying researchers who have the potential to make significant contributions to science.

Philanthropic Funding – Other Foundations

Doris Duke Charitable Foundation supports four national grantmaking programs including medical research.

The foundation has approved approximately 260 grants totaling $152 million in its Medical Research Program.

The foundation awards competitive grants under three grant-making strategies: Building the clinical research career ladder Improving African health through research Expanding clinical research frontiers

Organizations that Fund Cancer Research

American Association for Cancer ResearchAmerican Cancer SocietyAmerican Society of Clinical OncologyLance Armstrong FoundationMultiple Myeloma Research FoundationPancreatic Cancer Action NetworkProstate Cancer FoundationSusan G. Komen for the Cure

Organizations that Advocate for Cancer Research Funding

C3 – Colorectal Cancer CoalitionFriends of Cancer ResearchIntercultural Cancer Council CaucusInternational Myeloma FoundationNational Breast Cancer CoalitionNational Coalition for Cancer ResearchNational Prostate Cancer coalitionOvarian Cancer National AllianceSarcoma Foundation of America

Prevent Cancer Foundation Research Grants and Fellowships

Since 1985, peer-reviewed grants and fellowships have been awarded to more than 300 scientists from more than 150 of the leading academic medical centers nationwide.

We provide funding for innovative projects expected to lead to future funding from other peer-reviewed sources; can be basic, clinical, translational or population-based research

We receive and fund applications twice a year. Awards are for two years at $40,000 annually. Second year contingent upon satisfactory progress report at

end of year one.

Research Grants and Fellowships

Basic, clinical, translational and population-based research projects

Education programs in cancer prevention Early detection projects Behavioral intervention projects

Innovative Cancer Prevention Studies

Expanding our understanding of cancer and diet. Identifying new drugs or compounds that may prevent cancer.

Revealing genetic abnormalities that may make us susceptible to cancer.

Addressing the mutation process that turns normal cells into cancerous ones.

Understanding the body's immune system and how it can fight the disease.

Identifying markers that will help detect cancer at earlier, more curable stages.

Eligibility for Grants

Researchers at the instructor or assistant professor level.

More senior researchers who have shifted their area of interest toward primary and secondary cancer prevention.

Researchers at any academic level who need seed funding to test an innovative hypothesis.

Researchers from non-profit institutions (including academic institutions) are eligible to apply.

Eligibility for Fellowships

Postdoctoral level applicants only. Therefore, only graduate students who will have their doctoral degree before the project start date are eligible.

Researchers from non-profit institutions (including academic institutions) are eligible to apply.

Grant and fellowship applicants must state in writing that they have not received any funding from the tobacco industry for four years.

Semi-annual grants and fellowship selection process is a peer-review process similar to that used by the National Institutes of Health.

Research proposals are reviewed by members of a distinguished Scientific Review Panel from institutions such as:

National Cancer Institute Lombardi Cancer Center M.D. Anderson Cancer Center University of Pennsylvania Fox Chase Cancer Center Johns Hopkins Cancer Center Medical University of South Carolina

Grant Evaluation

Criteria for Awarding Grants

Must be prevention related Clarity of specific aims and significance to

cancer prevention Quality of the institutional research environment Methodology Relevance of supporting data Competence of principal investigator and

supporting personnel Appropriateness of project size to resources and

timeline Budget

Secondary Criteria

Selection of different cancer sites Selection of different areas of prevention Geographic location and other diversity factors

Scientific Review Panel Grading System

A - Outstanding B - Excellent C - Good D - Needs Improvement

Feedback provided Some awards contingent upon immediate revision Some resubmissions encouraged

Where Our Funds Come From

Mail appealsPlanned gifts

• Bequests• Charitable gift annuity• Charitable lead trust• Charitable remainder trust• Tangible property, e.g., real estate and securities

United Way, CFC and workplace campaignsOnline donationsMemorial giftsCause-related marketing (Buy and Give)

Research endowment

Special Events

Annual Spring Gala

Bad Beat on Cancer Annual Texas Hold'em Tournament

Annual Sporting Clays Invitational

Beneficiary Events

Holden Cup – MAPGA Tournament

18 Holes for Hope golf tournament

Climb for a Cause and a Cure

Play for Prevention

Partnerships for Funding Research

Individuals – Memorials and Tributes

Other Foundations• Susan G. Komen for the Cure• Living in Pink• Charles A. Kraenzle Colon Cancer Foundation• Family Foundations

Corporations• AstraZeneca• Bristol-Myers Squibb• Eli Lilly

Partnerships for Awarding Grants

American Association for Cancer Research (AACR)

American Society of Clinical Oncology (ASCO)

International Association of the Study of Lung Cancer (IASLC)

Intercultural Cancer Council (ICC)

American Society of Preventive Oncology (ASPO)

Value of Advocacy in Fundraising

Advocacy is defined as: Active support of an idea or cause, especially the act of

pleading or arguing for something. Speaking out on issues of concern. Organized activism to change policies, practices, and

beliefs.

Lobbying is defined as: Seeking to influence the passage or defeat of legislation or

administrative rules and regulations. Efforts to influence legislation by influencing the opinion of

legislators, legislative staff and government administrators directly involved in drafting legislative proposals.

Value of Advocacy in Fundraising

Congressional Families Cancer Prevention Program is a bipartisan network of spouses of Members of the House, the Senate, Cabinet and Supreme Court who share an interest in advancing cancer prevention, early detection and education.

Spouses:• Give presentations to civic and community groups.• Make radio and television presentations or public

service announcements.• Organize health fairs and conferences.• Write opinion/editorial pieces for publication.• Hold an annual awards luncheon.

Value of a Collective Voice

National Coalition for Cancer Research (NCCR)

Cancer Leadership Council (CLC)

One Voice Against Cancer (OVAC)

Coalition for the Advancement of Medical Research (CAMR)

Health Research Alliance

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THANK YOU!

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