The Pursuit of Perfection: Aspects of BiochemicalEvolution, Athel Cornish-Bowden

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The term Biochemical Evolution is used todescribe the evolution of the biochemicalprocesses and components of living organisms,such as the structure and function of biologicallyimportant molecules, metabolic pathways,subcellular structures, and cells. Although arelatively new subject, this field of research hasalready received great interest from bothacademia and industry because of the principlesand theory behind biochemical evolution haveenormous potential in the creation anddevelopment of new biologically activecompounds, drugs, and treatments for disease. However, almost every book that discussesevolution has ignored the role that biochemicalevolution plays, and so in his new book, AthelCornish-Bowden attempts to fill the knowledgegap for students, professional scientists and allinterested individuals. In The Pursuit ofPerfection, the author explains how thebiochemical processes that occur in living cells,long thought to be evidence of intelligent designrather than evolution, can now be understood asthe result of natural selection. For example, theinitial impression that metabolic pathwaysconsist of an almost haphazard collection ofreactions that happen to do the job turns out tobe quite false. When detailed studies are made tosee how the actual organization of a processcompares with other ways of achieving the sameresult, the one found in living organisms is foundto be the best possible, or at least very close to it.The style, content and organization of the bookare intended to make it accessible, interesting,and fun to read for both scientists, andscientifically-minded individuals.

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Systems Biology: Simulation of Dynamic NetworkStates . Biophysical models have been used inbiology for decades, but they have been limitedin scope and size. In this book, Bernhard ?.Palsson shows how network reconstructionsthat. May 26, 2011. . Bernhard ?. Palsson.Science

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